American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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JNJ 303 Quick inquiry Where to buy Suppliers range | JNJ 303 has been found to be a potent IKs blocker (IC50 = 64 nM) as well as a 11β-HSD1 inhibitor. Synonyms: JNJ303; JNJ-303; JNJ 303; AC-1; AC 1; AC1; 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3. 3. 1. 13, 7]dec-2-yl]-propanamide. Grades: ≥98% by HPLC. CAS No. 878489-28-2. Molecular formula: C21H29ClN2O4S. Mole weight: 440.98. | |
JNJ-31020028 Quick inquiry Where to buy Suppliers range | JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor. JNJ-31020028 bound with high affinity (IC50 = 8.07, human) and was 100-fold selective versus human Y(1), Y(4), and Y(5) receptors. JNJ-31020028 was demonstrated to be an antagonist (pK(B) = 8.04) in functional assays. Synonyms: JNJ31020028; JNJ 31020028; JNJ-31020028. Grades: 98%. CAS No. 1094873-14-9. Molecular formula: C34H36FN5O2. Mole weight: 565.6. | |
JNJ-37822681 dihydrochloride Quick inquiry Where to buy Suppliers range | JNJ-37822681 dihydrochloride is a potent, specific, centrally active and fast-dissociating antagonist of dopamine D2 receptor with a moderate binding affinity to dopamine D2L receptor (Ki = 158 nM). It has the potential to treat schizophrenia and bipolar disorder. Synonyms: 3-Pyridazinamine, N-(1-((3,4-difluorophenyl)methyl)-4-piperidinyl)-6-(trifluoromethyl)-, hydrochloride (1:2); N-(1-(3,4-difluorobenzyl)piperidin-4-yl)-6-(trifluoromethyl)pyridazin-3-amine dihydrochloride; N-[1-(3,4-Difluorobenzyl)-4-piperidinyl]-6-(trifluoromethyl)-3-pyridazinamine dihydrochloride. Grades: ≥98%. CAS No. 2108806-02-4. Molecular formula: C17H19Cl2F5N4. Mole weight: 445.26. | |
JNJ-38877605 Quick inquiry Where to buy Suppliers range | JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. Synonyms: JNJ-38877605; JNJ 38877605; JNJ38877605. Grades: >98%. CAS No. 943540-75-8. Molecular formula: C19H13F2N7. Mole weight: 377.36. | |
JNJ-38877618 Quick inquiry Where to buy Suppliers range | JNJ-38877618 is a potent and selective inhibitor of hepatocyte growth factor receptor (HGFR; MET) that exhibits inhibitory effects against solid tumors. Synonyms: OMO-1; HY-111050; 6-[Difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]quinoline. CAS No. 943540-74-7. Molecular formula: C20H12F2N6. Mole weight: 374.35. | |
JNJ-39327041 Quick inquiry Where to buy Suppliers range | JNJ-39327041 is a bio-active chemical compound. Synonyms: JNJ-39327041; JNJ 39327041; JNJ39327041. N-[(4R)-4-(3,4-dimethoxyphenyl)-4-[7-(4-ethylpiperazin-1-yl)-3-oxo-1H-isoindol-2-yl]butyl]-1,2-dimethylimidazole-4-sulfonamide;JNJ39327041;1H-Imidazole-4-sulfonamide, N-((4R)-4-(3,4-dimethoxyphenyl)-4-(4-(4-ethyl-1-piperazinyl)-1,3-dihydro-1-oxo-2H-isoindol-2-yl)butyl)-1,2-dimethyl-. Grades: 95%. CAS No. 1093069-32-9. Molecular formula: C31H42N6O5S. Mole weight: 610.77. | |
JNJ-39758979 dihydrochloride Quick inquiry Where to buy Suppliers range | JNJ-39758979 is a potent and selective histamine H4 antagonist (Ki = 12.5 nM) with >80-fold selectivity for H4 over other histamine receptors. It was shown to inhibit histamine-induced pruritus in healthy subjects. Synonyms: 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1620648-30-7. Molecular formula: C11H19N5·2HCl. Mole weight: 294.22. | |
JNJ-39933673 hemihydrate Quick inquiry Where to buy Suppliers range | TA-1887 is a selective Sodium Glucose Cotransporter 2 Inhibitor with pronounced antihyperglycemic effects in high-fat diet-fed KK (HF-KK) mice. It may be used for treatment of Type 2 Diabetes in the future. Uses: Type 2 diabetes. Synonyms: JNJ-39933673 hemihydrate; TA-1887 hemihydrate; JNJ 39933673 hemihydrate; TA 1887 hemihydrate; JNJ39933673 hemihydrate; TA1887 hemihydrate; (2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluoro-1H-indol-1-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol hemihydrate;1003005-29-5(Free). Grades: 98%. CAS No. 1404307-42-1. Molecular formula: 2(C24H26FNO5).H2O. Mole weight: 872.95. | |
JNJ-40355003 Quick inquiry Where to buy Suppliers range | JNJ-40355003 is a selective fatty acid amide hydrolase (FAAH) inhibitor. JNJ-40355003 can elevate the plasma levels of anandamide, oleoyl ethanolamide, and palmitoyl ethanolamide in animal model. Synonyms: JNJ-40355003; JNJ 40355003; JNJ40355003; 4-((3-(4-chlorophenoxy)phenyl)methyl)-N-3-pyridinyl-1-Piperazinecarboxamide. Grades: 98%. CAS No. 1394894-41-7. Molecular formula: C23H23ClN4O2. Mole weight: 422.91. | |
JNJ-40411813 Quick inquiry Where to buy Suppliers range | JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM. Synonyms: JNJ-40411813; JNJ 40411813; JNJ40411813; ADX71149; ADX 71149; ADX-71149. Grades: >98%. CAS No. 1127498-03-6. Molecular formula: C20H25ClN2O. Mole weight: 344.88. | |
JNJ-40418677 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 1146594-87-7. Pack Sizes: 5MG, 25MG. Mole weight: 480.44. Catalog: AP1146594877. Assay: ≥98% (HPLC). | |
JNJ-41443532 Quick inquiry Where to buy Suppliers range | This active molecular is a CCR2 receptor antagonist which is applicated for the treatment of type-2 diabetes mellitus under the development of Janssen Research & Development. In 2010, Phase-I clinical trials in Type-2 diabetes mellitus was on-going. in Belgium and USA. Uses: Type-2 diabetes mellitus. Synonyms: JNJ-41443532; JNJ 41443532; JNJ41443532; JNJ-41443532 Free Base; N-(2-((1-(trans-4-hydroxy-4-(5-thiazolyl)cyclohexyl)-3-azetidinyl)amino)-2-oxoethyl)-3-(trifluoromethyl)Benzamide. Grades: 98%. CAS No. 1228650-83-6. Molecular formula: C22H25F3N4O3S. Mole weight: 482.52. | |
JNJ 42041935 Quick inquiry Where to buy Suppliers range | JNJ 42041935. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: 1-(6-Chloro-5-(trifluoromethoxy)-1H-benzo[d]imidazol-2-yl)-1H-pyrazole-4-carboxylic Acid,1-[6-Chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1H-pyrazole-4-carboxylic Acid. CAS No. 1193383-09-3. Pack Sizes: 10MG. IUPAC Name: 1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]pyrazole-4-carboxylic acid. Molecular formula: C12H6ClF3N4O3. Mole weight: 346.65. Catalog: APS1193383093. SMILES: OC (=O)c1cnn (c1)c2nc3cc (OC (F) (F)F)c (Cl)cc3[nH]2. Format: Neat. Shipping: Room Temperature. | |
JNJ-42041935 Quick inquiry Where to buy Suppliers range | JNJ 42041935. CAS No. 1193383-09-3. | |
JNJ-42041935 Quick inquiry Where to buy Suppliers range | JNJ-42041935 is a potent (pK(I) = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes. JNJ-42041935 is a new pharmacological tool, which can investigate PHD inhibition and demonstrate that PHD inhibitors offer great promise for the treatment of inflammation-induced anemia. Synonyms: JNJ-42041935; JNJ 42041935; JNJ42041935. Grades: 98%. CAS No. 1193383-09-3. Molecular formula: C12H6ClF3N4O3. Mole weight: 346.65. | |
JNJ-42153605 Quick inquiry Where to buy Suppliers range | JNJ-42153605 is a selective positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor (EC50 = 17 Nm) with an acceptable pharmacokinetic profile in rodent and nonrodent species. Synonyms: 3-(cyclopropylmethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine; 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl(1,2,4)triazolo(4,3-a)pyridine; JNJ-42153605; JNJ 42153605; JNJ42153605. CAS No. 1254977-87-1. Molecular formula: C22H23F3N4. Mole weight: 400.44. | |
JNJ-42165279 Quick inquiry Where to buy Suppliers range | JNJ-42165279 is a fatty acid amide hydrolase (FAAH) inhibitor developed by Janssen Pharmaceutica and IC50 value is 70 nM. It is described as a covalently binding but slowly reversible selective inhibitor of FAAH. Phase II human trials for the treatment of anxiety disorders and major depressive disorder is on-going. Uses: Anxiety disorders and major depressive disorder. Synonyms: N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide; JNJ-42165279; JNJ 42165279; JNJ42165279. Grades: 98%. CAS No. 1346528-50-4. Molecular formula: C18H17ClF2N4O3. Mole weight: 410.81. | |
JNJ-42165279 hydrochloride Quick inquiry Where to buy Suppliers range | JNJ-42165279 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor. JNJ-42165279 covalently inactivates the FAAH enzyme, but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. Synonyms: JNJ-42165279 hydrochloride; JNJ 42165279 hydrochloride; JNJ42165279 hydrochloride; 1-Piperazinecarboxamid?e, N-(4-chloro-3-pyridinyl)?-4-[(2,?2-difluoro-1,?3-benzodioxol-5-yl)?methyl]?-, hydrochloride (1:1). CAS No. 1346528-52-6. Molecular formula: C18H17ClF2N4O3. HCl. Mole weight: 447.3. | |
JNJ-42259152 Quick inquiry Where to buy Suppliers range | This molecular is a phosphodiesterase 10A PET tracer. Related studies show that PDE10A activity can be reliably quantified and simplified using a reference tissue model with the frontal cortex as reference and a 60-min acquisition period. Uses: Phosphodiesterase 10a pet tracer. Synonyms: JNJ-42259152; JNJ 42259152; JNJ42259152. UNII-B1QHA9M0I6;2-((4-(1-(2-fluoroethyl)-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)-3,5-dimethylpyridine. Grades: 98%. CAS No. 1301167-87-2. Molecular formula: C24H23FN4O. Mole weight: 402.46. | |
JNJ 42396302 Quick inquiry Where to buy Suppliers range | JNJ 42396302 is an Antipsychotics originated by Janssen-Cilag. But no development has been reported yet. Uses: Antipsychotics. Synonyms: JNJ 42396302; JNJ42396302; JNJ-42396302. UNII-P5M4972608;3-(6-(2-methoxyethyl)-3-pyridinyl)-2-methyl-8-(4-morpholinyl)-Imidazo(1,2-b)pyridazine. Grades: 98%. CAS No. 1298030-18-8. Molecular formula: C19H23N5O2. Mole weight: 352.43. | |
JNJ4796 Quick inquiry Where to buy Suppliers range | JNJ4796 is an oral active influenza virus fusion inhibitor. Synonyms: EZ7; JNJ-4796; JNJ 4796. Grades: 98%. CAS No. 2241664-16-2. Molecular formula: C28H27N9O3. Mole weight: 537.6. | |
JNJ 47965567 Quick inquiry Where to buy Suppliers range | JNJ 47965567 has been found to be a selective P2X7 antagonist and is brain penetrant. Synonyms: JNJ-47965567; JNJ 47965567; JNJ47965567. 2-(Phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl-3-pyridinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1428327-31-4. Molecular formula: C28H32N4O2S. Mole weight: 488.64. | |
JNJ 47965567 Quick inquiry Where to buy Suppliers range | JNJ 47965567. Group: Biochemicals. Grades: Highly Purified. CAS No. 1428327-31-4. Pack Sizes: 10mg. Molecular Formula: C28H32N4O2S, Molecular Weight: 488.64. US Biological Life Sciences. | Worldwide |
JNJ 5207787 Quick inquiry Where to buy Suppliers range | JNJ 5207787 has been found to be a selective NPY Y2 antagonist (IC50 = 0.1 μM). Synonyms: JNJ-5207787; JNJ 5207787; JNJ5207787; (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide; trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]acrylamide. Grades: ≥98% by HPLC. CAS No. 683746-68-1. Molecular formula: C32H38N4O2. Mole weight: 510.67. | |
JNJ 5207852 Quick inquiry Where to buy Suppliers range | JNJ 5207852. Group: Biochemicals. Alternative Names: 1-[3- (4- ( (Piperidin-1-yl) methyl) phenoxy) propyl]piperidine. Grades: Highly Purified. CAS No. 398473-34-2. Pack Sizes: 10mg. Molecular Formula: C20H32N2O, Molecular Weight: 316.48. US Biological Life Sciences. | Worldwide |
JNJ 5207852 dihydrochloride Quick inquiry Where to buy Suppliers range | Cas No. 398473-34-2. | |
JNJ-54717793 Quick inquiry Where to buy Suppliers range | JNJ-54717793 is a selective antagonist with a preference for Ox1R over Ox2R. Ox1R and Ox2R were indicated to play important roles in the control of sleep-wake, the regulation of food intake, addiction, reward, mood, panic, anxiety and stress. JNJ-54717793 disrupted REM time sleep in Ox2R knockout mice model, and attenuated panic in a CO2-induced model. Uses: Disrupt rem time sleep, attenuate panic. Synonyms: JNJ 54717793; JNJ54717793. CAS No. 1628843-99-1. Molecular formula: C22H18F4N6O. Mole weight: 458.41. | |
JNJ 55511118 Quick inquiry Where to buy Suppliers range | JNJ 55511118 has been found to be an AMPA receptor modulator and could probably be used as an anticonvulsant. Synonyms: JNJ-55511118; JNJ 55511118; JNJ55511118; 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: ≥98% by HPLC. CAS No. 2036081-86-2. Molecular formula: C14H8ClF3N2O2. Mole weight: 328.67. | |
JNJ-632 Quick inquiry Where to buy Suppliers range | JNJ-632 is a modulator of hepatitis B virus (HBV) capsid assembly. It induces the formation of morphologically intact viral capsids, as demonstrated by size exclusion chromatography and electron microscopy studies. Uses: Antiviral agents. Synonyms: N-(4-fluoro-3-methylphenyl)-3-[[(3S)-oxolan-3-yl]sulfamoyl]benzamide. Grades: ≥98%. CAS No. 1572510-42-9. Molecular formula: C18H19FN2O4S. Mole weight: 378.42. | |
JNJ 63533054 Quick inquiry Where to buy Suppliers range | JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain and cell penetrant. JNJ 63533054 is selective for GPR139 over a panel of GPCRs, ion channels and transporters, including GPR142. Synonyms: 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide; GTPL8766; GTPL 8766; GTPL-8766; JNJ 63533054; JNJ63533054; JNJ-63533054. Grades: 98%. CAS No. 1802326-66-4. Molecular formula: C17H17ClN2O2. Mole weight: 316.785. | |
JNJ-64413739 Quick inquiry Where to buy Suppliers range | JNJ-64413739 is a potential P2X7 receptor positron emission tomography (PET) tracer, which is potent and selective of human and mice P2X7 receptor. Uses: Potential p2x7 receptor positron emission tomography (pet) tracer. Synonyms: JNJ 64413739; JNJ64413739. Molecular formula: C17H13F4N7O. Mole weight: 407.3. | |
JNJ-64619178 Quick inquiry Where to buy Suppliers range | JNJ-64619178 is a selective PRMT5 inhibitor with potent in vitro and in vivo activity. JNJ-64619178 binds simultaneously to the SAM- and protein substrate- binding pockets of the PRMT5/MEP50 complex with a pseudo-irreversible mode-of-action. It can be developed as the treatment of some malignancies. Uses: Enzyme inhibitors. Synonyms: (1S,2R,3S,5R)-3-[2-(2-Amino-3-bromoquinolin-7-yl)ethyl]-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol. CAS No. 2086772-26-9. Molecular formula: C22H23BrN6O2. Mole weight: 483.36. | |
JNJ-7706621 Quick inquiry Where to buy Suppliers range | JNJ-7706621 is a novel cell cycle inhibitor that showed potent inhibition of several cyclin-dependent kinases (CDK) and Aurora kinases and selectively blocked proliferation of tumor cells of various origins but was about 10-fold less effective at inhibiting normal human cell growth in vitro. In human cancer cells, treatment with JNJ-7706621 inhibited cell growth independent of p53, retinoblastoma, or P-glycoprotein status; activated apoptosis; and reduced colony formation. At low concentrations, JNJ-7706621 slowed the growth of cells and at higher concentrations induced cytotoxicity. Synonyms: JNJ-7706621; JNJ-7706621; JNJ-7706621. CAS No. 443797-96-4. Molecular formula: C15H12F2N6O3S. Mole weight: 394.36. | |
JNJ-7706621 Quick inquiry Where to buy Suppliers range | JNJ-770662 is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. JNJ-770662 has been shown to induce growth suppression and mitotic defects, these results suggest that JNJ-7706621 could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma. Group: Biochemicals. Alternative Names: N3-[4-(Aminosulfonyl)phenyl]-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazole-3,5-diamine; 4- [ [5-Amino-1- (2, 6-difluorobenzoyl) -1H- [1, 2, 4] triazol-3-yl] amino] benzenesulfonamide; JNJ 770662. Grades: Highly Purified. CAS No. 443797-96-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
JNJ-7777120 Quick inquiry Where to buy Suppliers range | JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors. Synonyms: JNJ7777120; JNJ-7777120; JNJ 7777120. Grades: >98%. CAS No. 459168-41-3. Molecular formula: C14H16ClN3O. Mole weight: 277.75. | |
JNJ7777120 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 459168-41-3. Pack Sizes: 5MG, 25MG. Mole weight: 277.75. Catalog: AP459168413. Assay: ≥98% (HPLC). | |
JNJ7925476 HCl Quick inquiry Where to buy Suppliers range | JNJ7925476 HCl is a novel triple monoamine uptake inhibitor. It blocks the serotonin transporter (SERT), norepinephrine transporter (NET) and dopamine transporter (DAT) in the central nervous system. Its ED50 values for SERT, NET, and DATwere 0.18, 0.09 and 2.4 mg/kg, respectively in rat brain. It is used as a TRI antidepressant. It was under the development by Johnson & Johnson. Uses: Jnj7925476 hcl is used as a tri antidepressant. Synonyms: JNJ-7925476; JNJ 7925476; JNJ7925476; JNJ-7925476 HCl. Pyrrolo(2,1-a)isoquinoline, 6-(4-ethynylphenyl)-1,2,3,5,6,10b-hexahydro-, hydrochloride (1:1), (6R,10bS)-rel-;Pyrrolo(2,1-a)isoquinoline, 6-(4-ethynylphenyl)-1,2,3,5,6,10b-hexahydro-, hydrochloride, trans-;JNJ-7925476 HCl;(6S,10bR)-6-(4-ethynylphenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline hydrochloride. Grades: >98%. CAS No. 109085-56-5. Molecular formula: C20H20ClN. Mole weight: 309.84. | |
JNJ DGAT2-A Quick inquiry Where to buy Suppliers range | JNJ DGAT2-A has been found to be a DGAT2 inhibitor (IC50 = 140 nM) and also a useful intermediate. Synonyms: JNJ-DGAT2-A; JNJDGAT2A; JNJ DGAT2 A; 3-Bromo-4-[2-fluoro-4-[[4-oxo-2-[[2- (pyridin-2-yl) ethyl]amino]-1, 3-thiazol-5- (4H) ylidene]methyl]phenoxy]benzonitrile. Grades: ≥98% by HPLC. CAS No. 1962931-71-0. Molecular formula: C24H16BrFN4O2S. Mole weight: 523.38. | |
JNK-IN-7 Quick inquiry Where to buy Suppliers range | Covalent modification of IRAK1 by JNK-IN-7 is a possibility and subsequent biochemical kinase assay revealed anIC50 of ~10 nM against IRAK1. JNK-IN-7 exhibited binding inhibition of 95% or more to approximately 14 kinases at the concentration of 1.0 μM. JNK-IN-7 was next tested for its ability to inhibit the enzymatic activity of a panel of 121 kinases at a concentration of 1.0 μM. Synonyms: JNK-IN-7; JNK inhibitor;JNKIN7; JNK IN 7; JNK-IN-7. Grades: >98%. CAS No. 1408064-71-0. Molecular formula: C28H27N7O2. Mole weight: 493.56. | |
JNK-IN-8 Quick inquiry Where to buy Suppliers range | JNK-IN-8 inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM, respectively. Uses: Protein kinase inhibitors. Synonyms: JNK-IN-8; JNK-IN 8; JNK-IN8; JNK Inhibitor XVI; c-Jun N-terminal Kinase Inhibitor XVI. Grades: >98%. CAS No. 1410880-22-6. Molecular formula: C29H29N7O2. Mole weight: 507.59. | |
JNK Inhibitor II (Anthra[1,9-cd]pyrazol-6(2H)-one, 1,9-pyrazoloanthrone, SP600125, SAPK Inhibitor II) Quick inquiry Where to buy Suppliers range | A potent, cell-permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50=40nM for JNK-1 and JNK-2 and 90 nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold greater selectivity for JNK as compared to ERK1 and p38-2 MAP kinases. Inhibits the phosphorylation of c-Jun and blocks the expression of IL-2, IFN-y, TNF-a, and COX-2 in cells. Blocks IL-1-induced accumulation of phospho-Jun and induction of c-Jun transcription. Group: Biochemicals. Grades: Highly Purified. CAS No. 129-56-6. Pack Sizes: 5mg, 25mg, 50mg. Molecular Formula: C14H8N2O, Molecular Weight: 220.2. US Biological Life Sciences. | Worldwide |
JNK Inhibitor III, Cell-Permeable Quick inquiry Where to buy Suppliers range | The JNK Inhibitor III, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 4413.22. Catalog: IAR42417778. Assay: ≥95% (HPLC). | |
JNK Inhibitor III, Cell-Permeable, Negative Control Quick inquiry Where to buy Suppliers range | The JNK Inhibitor III, Cell-Permeable, Negative Control controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 4413.22. Catalog: IAR42417779. Assay: ≥95% (HPLC). | |
JNK Inhibitor II, Negative Control - CAS 54642-23-8 Quick inquiry Where to buy Suppliers range | The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 54642-23-8. Pack Sizes: 1MG. Mole weight: 234.25. Catalog: AP54642238. Assay: ≥97% (HPLC). | |
JNK Inhibitor I, (L)-Form, Cell-Permeable Quick inquiry Where to buy Suppliers range | The JNK Inhibitor I, (L)-Form, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 3923.55. Catalog: IAR42417772. Assay: ≥97% (HPLC). | |
JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control Quick inquiry Where to buy Suppliers range | The JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 1MG. Mole weight: 1589.90. Catalog: IAR42417773. Assay: ≥97% (HPLC). | |
JNK Inhibitor IX Quick inquiry Where to buy Suppliers range | JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6.7 for JNK2 and JNK3, respectively. Synonyms: TCS JNK 5a, TCS-JNK-5a, JNK Inhibitor IX, SC-202671, SC 202671, SC202671. Grades: >98%. CAS No. 312917-14-9. Molecular formula: C20H16N2OS. Mole weight: 332.42. | |
JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable Quick inquiry Where to buy Suppliers range | The JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 2MG. Mole weight: 2883.42. Catalog: IAR42417781. Assay: ≥97% (HPLC). | |
JNK Inhibitor VI, TI-JIP153-163 Quick inquiry Where to buy Suppliers range | The JNK Inhibitor VI, TI-JIP153-163 controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 2MG. Mole weight: 1341.60. Catalog: IAR42417780. Assay: ≥97% (HPLC). | |
JNK Inhibitor XIV, SR-3306 Quick inquiry Where to buy Suppliers range | The JNK Inhibitor XIII, SR-3306 controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. Pack Sizes: 10MG. Mole weight: 490.56. Catalog: IAR42417787. Assay: ≥95% (HPLC). | |
JNK Inhibitor XVI, JNK-IN-8 ( (E) -3- (4- (dimethylamino) but-2-enamido) -N- (3-methyl-4- ( (4- (pyridin-3-yl) pyrimidin-2-yl) amino) phenyl) benzamide) Quick inquiry Where to buy Suppliers range | A cell-permeable, selective, and irreversible type 2 inhibitor of c-Jun N-terminal kinases (JNK) (IC50=4.67nM, 18.7nM, 980pM for JNK1, JNK2, and JNK3, respectively). Forms a covalent adduct with the conserved cysteine residue (Cys116 in JNK1) and binds to JNK in an extended type 2 conformation. Blocks the phosphorylation of c-Jun in cells (EC50=486nM in HeLa cells; 338nM in A375 cells). Exhibits greater cellular specificity for JNK when compared to 40 other kinases screened using a cell-based assay. Shows weaker binding to KIT mutants (IC50=92nM for V559D and 56nM for T670I) and RIOK2 (120nM). Does not show any significant inhibitory activity against various other kinases, including ERK, p38, Akt, MSK, and RSK. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
JNK Inhibitor XV, IQ-1S (11H-Indeno[1,2-b]quinoxalin-11-one oxime, sodium salt) Quick inquiry Where to buy Suppliers range | A cell-permeable indenoquinoxalinone-oxime (IQ) compound that acts as a potent, non-toxic, reversible, ATP-competitive, high-affinity inhibitor of JNK (=390, 360 and 87nM for JNK1, JNK2 and JNK3, respectively) with moderate selectivity over CK1d, PI 3-Ky, and MKNK2 (IC50=1.4, 1.2, and 1.8uM, respectively). Shown to reduce c-Jun-Ser63 phosphorylation, and block the production of LPS-induced TNF-a (IC50 = 250nM) and IL-6 (IC50=610nM) in MonoMac-6 monocytic cells and in human hPBMCs, respectively. Also shown to inhibit NF-kB/AP-1 reporter activity (IC50=1.8uM) in human THP1-Blue monocytic cells and diminish nitric oxide production in murine J774-A.1 macrophages (IC50=12.5uM). Exhibits favorable pharmacokinetics properties and efficiently reduces ovalbumin-induced CD+ T-cell immune inflammation in a murine delayed-type hypersensitivity model (12.5mg/kg, two per day dosage, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H?N?Ona, Primary Target: JNK1,2,3. US Biological Life Sciences. | Worldwide |
Jojoba Castor Beads Quick inquiry Where to buy Suppliers range | Tiny, spherically shaped beads consisting of natural jojoba oil and castor oil, round shape warrants effective but gentle exfoliation, not animal tested. 40/60 mesh size, white/vanilla color, ideal for exfoliation on delicate skin such as the face, lip and cuticle exfoliation. Uses: Facial scrubs, specialty bar soap, body washes, body scrubs, shower gels. Group: Sensory Modifiers. CAS No. 92457-12-0 / 8001-78-3. Product ID: ACM92457120. Appearance: Small, round beads, faint odor. | |
Jojoba Gel Quick inquiry Where to buy Suppliers range | Anhydrous transparent viscous gel consisting of jojoba oil (Simmondsia chinensis) combined with polymers (ethylene-propylene-styrene copolymer & ethylene-butylene-styrene copolymer). Uses: All kinds of emulsions (creams, lotions, cleansers, hair creams, makeup foundations), lip care products, massage oils, baby oils. Group: Skin Actives. CAS No. 61789-91-1 / 66070-58-4 / 68648-89-5. Product ID: ACM61789911-3. Appearance: Viscous pale yellow fluid, odorless. | |
Jojoba oil Quick inquiry Where to buy Suppliers range | Jojoba oil. Group: Heterocyclic Organic Compound. Alternative Names: jojobaoilfromsimmondsiachinensis; Jojobawax; WaxesandWaxysubstances, jojoba; OIL OF JOJOBA;OIL, JOJBA;EMALEX J J O-V;JOJOBA BEAN OIL;JOJOBAE OELUM. CAS No. 61789-91-1. Mole weight: 0. Density: 0.87g/mL at 20°C. Safty Description: 24/25. | |
Jojoba Oil Golden Quick inquiry Where to buy Suppliers range | Jojoba Oil Golden. | CA, FL & NJ |
Jojoba Oil, USDA Certified Organic Quick inquiry Where to buy Suppliers range | Organic pure liquid wax (not an oil as such) derived from the seeds of a plant (simmondsia chinensis) growing in the Sonora desert in the USA, composed of different liquid wax esters similar to human sebaceous, based on fatty acids & fatty alcohols (no triglycerides), cold-pressed, insoluble in water. Uses: Lotions, creams, nourishing skin & hair care products, body washes, shampoos, baby products, sun care & after sun products, makeup products, bath oils, facial rinses, hair rinses. Group: Emollients/Oils/Wax. CAS No. 61789-91-1. Product ID: ACM61789911-2. Appearance: Clear oily golden liquid, no or faint odor. | |
Jojoba Pearls, Green Quick inquiry Where to buy Suppliers range | Jojoba pearls are tiny, spherically shaped beads consisting of hydrogenated natural jojoba oil (= jojoba wax), round shape warrants effective but gentle exfoliation. Ultrafine pearl size (40/60 mesh size or 250-425 microns) is ideal for exfoliation on delicate skin such as the face, lip and cuticle exfoliation. Uses: Shampoos, specialty bar soap, lotions, creams, body washes, body scrubs, shower gels. Group: Surfactants/Emulsifiers. CAS No. 61789-91-1 / 12001-99-9. Product ID: ACM61789911-5. Appearance: Small, round green beads, faint odor. | |
Jojoba Pearls, Orange Quick inquiry Where to buy Suppliers range | Jojoba pearls are tiny, spherically shaped beads consisting of hydrogenated natural jojoba oil (= jojoba wax), round shape warrants effective but gentle exfoliation. Ultrafine pearl size (40/60 mesh size or 250-425 microns) is ideal for exfoliation on delicate skin such as the face, lip and cuticle exfoliation. Uses: Shampoos, specialty bar soap, lotions, creams, body washes, body scrubs, shower gels. Group: Surfactants/Emulsifiers. CAS No. 61789-91-1 / 2379-74-0 / 51274-00-1. Product ID: ACM61789911-7. Appearance: Small, round orange beads, faint odor. | |
Jojoba Pearls, Red Quick inquiry Where to buy Suppliers range | Jojoba pearls are tiny, spherically shaped beads consisting of hydrogenated natural jojoba oil (= jojoba wax), round shape warrants effective but gentle exfoliation. Ultrafine pearl size (40/60 mesh size or 250-425 microns) is ideal for exfoliation on delicate skin such as the face, lip and cuticle exfoliation. Uses: Shampoos, specialty bar soap, lotions, creams, body washes, body scrubs, shower gels. Group: Surfactants/Emulsifiers. CAS No. 61789-91-1 / 2379-74-0. Product ID: ACM61789911-6. Appearance: Small, round red beads, faint odor. | |
Jojoba Pearls, White Quick inquiry Where to buy Suppliers range | Jojoba pearls are tiny, spherically shaped beads consisting of hydrogenated natural jojoba oil (= jojoba wax), round shape warrants effective but gentle exfoliation. Ultrafine pearl size (40/60 mesh size or 250-425 microns) is ideal for exfoliation on delicate skin such as the face, lip and cuticle exfoliation. Uses: Shampoos, specialty bar soap, lotions, creams, body washes, body scrubs, shower gels. Group: Surfactants/Emulsifiers. CAS No. 61789-91-1. Product ID: ACM61789911-4. Appearance: Small, round white beads, faint odor. | |
Jojoba Protein HP, Hydrolyzed Quick inquiry Where to buy Suppliers range | Hydrolyzed (fragmented) proteins enzymatically extracted from the jojoba plant, 100% natural, MW 1800-2400 kD. Precipitations of proteins in the bottom of the container is normal. Uses: Lotions, creams, sun care products & after sun products, hair shampoos, leave-in-conditioners, hair mousse, shower gels, makeup products (mascara, foundations). Group: Skin Actives. CAS No. 100684-35-3 / 7732-18-5 / 122-99-6 / 24634-61-5. Product ID: ACM100684353. Appearance: Dark brown, cloudy, faint odor. | |
Jolkinolide B Quick inquiry Where to buy Suppliers range | Jolkinolide B. Group: Biobased Products. Alternative Names: 1,4-Dibutyl-N-(2,6-dimethylphenyl)piperazine-2-carboxamide,nitrous acid. Grades: 98%. CAS No. 37905-08-1. Product ID: BBC37905081. Molecular formula: C20H26O4. Mole weight: 330.42. IUPAC Name: (1S, 3R, 8R, 10R, 11R, 12R, 17R)-5, 12, 16, 16-tetramethyl-2, 7, 9-trioxahexacyclo[9.8.0.01, 3.04, 8.08, 10.012, 17]nonadec-4-en-6-one. Appearance: Powder. Density: 1.28±0.1 g/ml. SMILES: CC1=C2[C@@H]3[C@]4 (O3)CC[C@H]5[C@] ([C@@H]4[C@@H]6[C@]2 (O6)OC1=O) (CCCC5 (C)C)C. | |
Jolkinolide B Quick inquiry Where to buy Suppliers range | Jolkinolide B. Group: Biochemicals. Grades: Plant Grade. CAS No. 37905-08-1. Pack Sizes: 10mg. Molecular Formula: C20H26O4, Molecular Weight: 330.42. US Biological Life Sciences. | Worldwide |
Jones reagent Quick inquiry Where to buy Suppliers range | Jones reagent. Alternative Names: Chromium(6+) trioxide; Chrome (trioxyde de) [French]; I14-18129; Chromium trioxide, anhydrous; UN1463; Epitope ID:158535; Chromium trioxide solution in sulfuric acid; Monochromium trioxide; AC1L24SL; Chromium trioxide, anhydrous [UN1463] [Oxidizer]. CAS No. 65272-70-0. Molecular formula: CrO3;CrO3;CrO3. Mole weight: 99.993g/mol. IUPAC Name: trioxochromium. Exact Mass: 99.925g/mol. EC Number: 215-607-8. Melting Point: 385 ° F (NTP, 1992);197 deg C;197 °C;387°F (Decomposes). Solubility: Very soluble (NTP, 1992);In water, 169 g/100 g water at 25 deg C;In water, 1667 g/L (EU Method A.6 (Water Solubility));In water, 167.299 lb/100 lb water at 70 deg F;Soluble in ethyl alcohol, ethyl ether, sulfuric and nitric acids;Soluble in sulfuric acid and organic solvents;Chromium(VI) oxide dissolves in water to form chromic acids; the solubility depends only slightly on temperature. A saturated solution contains 166 g of CrO3 at 20 deg C and 199 g of CrO3 at 90 deg C per 100 mL of water.;Solubility in water, g/100ml: 61.7 (good);63%. Density: 2.7 (NTP, 1992);2.70;2.7 g/cm³;2.70 (CrO3). SMILES: O=[Cr](=O)=O. InChI: InChI=1S/Cr.3O. InChIKey: WGLPBDUCMAPZCE-UHFFFAOYSA-N. H-Bond Acceptor: 3. Monoisotopic Mass: 99.925g/mol. | |
Joro spider toxin(jstx-3) Quick inquiry Where to buy Suppliers range | Off-white lyophilized solid. Group: Heterocyclic Organic Compound. Alternative Names: JSTX-3;JORO SPIDER TOXIN;JORO-SPIDER-TOXIN, [125I];JORO SPIDER TOXIN JSTX-3; N1- (5- (3- (3- (4-Aminobutylamino) propylamino) propanamido) pentyl) -2- (2- (2, 4-dihydroxyphenyl) acetamido) succinamide; (S) -N-[5-[[3-[[4-[ (3-Aminopropyl) amino]butyl]amino]propionyl]amino]. CAS No. 112163-33-4. Molecular formula: C27H47N7O6. Mole weight: 565.71. | |
Josamycin Quick inquiry Where to buy Suppliers range | Josamycin. Uses: For analytical and research use. Group: European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Alternative Names: Josamycin, (4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methylbutanoyl)-a-l-ribo-hexopyranosyl]-3-(dimethylamino)-ß-d-glucopyranosyl]oxy]-10-hydroxy-5-methoxy-9,16-dimethyl-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-2-one. CAS No. 16846-24-5. IUPAC Name: [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate. Molecular formula: C42H69NO15. Mole weight: 828.00. Catalog: APS16846245. SMILES: CO[C@H]1[C@@H] (CC (=O)O[C@H] (C)C\C=C\C=C\[C@H] (O)[C@H] (C)C[C@H] (CC=O)[C@@H]1O[C@@H]2O[C@H] (C)[C@@H] (O[C@H]3C[C@@] (C) (O)[C@@H] (OC (=O)CC (C)C)[C@H] (C)O3)[C@@H] ([C@H]2O)N (C)C)OC (=O)C. Format: Neat. Product Type: API. Shipping: Ice pack (-20°C). | |
Josamycin Quick inquiry Where to buy Suppliers range | Josamycin is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Synonyms: YL-704A3; YL 704A3; YL 704 A3; Leucomycin A3; Turimycin A5; Kitasamycin A3; Josamycine. Grades: 95%. CAS No. 16846-24-5. Molecular formula: C42H69NO15. Mole weight: 828. | |
Josamycin Quick inquiry Where to buy Suppliers range | light yellow powder. Group: Main Products. Alternative Names: antibioticyl-704a3; kitasamycina3; leucomycinv, 3-acetate4(supb)-(3-methylbutanoate); turimycina5; JOSAMYCIN; LEUCOMYCIN V,3-AC-ETA 4B-(3-METHYLBUTANOATE);LEUCOMYCIN V,3-ACETA 4BETA-(3-METHYL BUTANOATE);LEUCOMYCIN A3. Grades: 98%. CAS No. 16846-24-5. Molecular formula: C42H69NO15. Mole weight: 827.99. IUPAC Name: josamycin. Exact Mass: 827.46700. Boiling Point: 877.8ºC at 760mmHg. Melting Point: 131.5?. Flash Point: 484.7ºC. Density: 1.2g/cm3. | |
Josamycin 10 μg/mL in Acetonitrile Quick inquiry Where to buy Suppliers range | Josamycin 10 μg/mL in Acetonitrile. Uses: For analytical and research use. Group: Pharma & Vet Compounds & Metabolites; Pharma & Vet Compounds & Metabolites. Alternative Names: Josamycin, (4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methylbutanoyl)-a-l-ribo-hexopyranosyl]-3-(dimethylamino)-ß-d-glucopyranosyl]oxy]-10-hydroxy-5-methoxy-9,16-dimethyl-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-2-one. CAS No. 16846-24-5. IUPAC Name: [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6S)-6-[[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate. Molecular formula: C42H69NO15. Mole weight: 828.00. Catalog: APS16846245A. SMILES: CO[C@H]1[C@@H] (CC (=O)O[C@H] (C)C\C=C\C=C\[C@H] (O)[C@H] (C)C[C@H] (CC=O)[C@@H]1O[C@@H]2O[C@H] (C)[C@@H] (O[C@H]3C[C@@] (C) (O)[C@@H] (OC (=O)CC (C)C)[C@H] (C)O3)[C@@H] ([C@H]2O)N (C)C)OC (=O)C. Format: Single Solution. Shipping: Room Temperature. |