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10,11-Dehydrocurvularin
It is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including curvularia, penicillium and alternaria. It inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in alternaria alternata. Synonyms: (4R,8E)-4,5,6,7-Tetrahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10(1H)-dione; (+)-(10E,15R)-10,11-Dehydrocurvularin; ent-Dehydrocurvularin; (R)-10,11-Dehydrocurvularin; 4,5-[[(7R)-1-Oxo-2-octene-1,7-diyl]oxy(1-oxoethane-1,2-diyl)]benzene-1,3-diol. Grade: >98% by HPLC. CAS No. 1095588-70-7. Molecular formula: C16H18O5. Mole weight: 290.31.
10,11-dihydropicromycin
10,11-dihydropicromycin is produced by the strain of Streptomyces venezuelae. It has anti-gram-positive bacterial activity. Synonyms: Dihydropicromycin; Picromycin, 10,11-dihydro-; 14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradecan-6-yl 3,4,6-trideoxy-3-(dimethylamino)hexopyranoside. CAS No. 27656-56-0. Molecular formula: C28H49NO8. Mole weight: 527.69.
10-Decarbamoyloxy-9-dehydromitomycin B
10-Decarbamoyloxy-9-dehydromitomycin B is a mitane antibiotic produced by Streptomyces caespitosus KY 2072. It has anti-Gram-positive bacteria and anti-tumor cell activity. Synonyms: Mitomycin H; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxy-8-methylene-, (1aS-(1a-alpha,8a-alpha,8b-alpha))-. CAS No. 74148-44-0. Molecular formula: C15H16N2O4. Mole weight: 288.30.
10-Decarbomethoxyaclacinomycin A
10-Decarbomethoxyaclacinomycin A is an anthracycline antibiotic produced by Streptomyces galilaeus MA144-Mlt mutant strain KE303. It has anti-tumor and gram-positive bacteria activity. Synonyms: 7-epi-10-Decarbomethoxyaclacinomycin A. CAS No. 76264-91-0. Molecular formula: C40H51NO13. Mole weight: 753.83.
10-Deoxymethymycin
It is produced by the strain of Streptomyces venezuelae. 10-Deoxymethymycin is a biochemical. Synonyms: Antibiotic YC 17; YC-17. Grade: >98%. CAS No. 11091-33-1. Molecular formula: C25H43NO6. Mole weight: 453.61.
10-Dihydrosteffimycin A
It is produced by the strain of Actinoplanes utahensis. 10-Dihydrosteffimycin A has anti-gram-positive bacterial activity. Synonyms: 3,4,10,12-tetrahydroxy-2,8-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 6-deoxy-2-O-methylhexopyranoside. CAS No. 75086-96-3. Molecular formula: C28H32O13. Mole weight: 576.54.
10-Dihydrosteffimycin B
It is produced by the strain of Chaetomium sp. BB 427. 10-Dihydrosteffimycin B has anti-gram-positive bacterial activity. Synonyms: 3,4,10,12-Tetrahydroxy-2,8-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 6-deoxy-2,4-di-O-methylhexopyranoside. CAS No. 75086-97-4. Molecular formula: C29H34O13. Mole weight: 590.57.
10-Hydroxyundeca-2,4,6,8-tetraynamide
10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic produced by Mycena viridimarginata 7638. It has anti-gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity. Synonyms: 10-Hydroxy-undeca-2,4,6,8-tetraynamide. CAS No. 83475-37-0. Molecular formula: C11H7NO2. Mole weight: 185.18.
10-Norparvulenone
It is originally isolated from Microsphaeropsis sp. FO-5050. 10-Norparvulenone inhibits viral Sialidase by IC50 of 21 μg/mL and inhibits influenza virus A/PR/8/34 replication in MDCK cells. Synonyms: MLS004711975; 3,4-dihydro-4,8-dihydroxy-7-(hydroxymethyl)-6-methoxy-1(2H)-naphthalenone. CAS No. 618104-32-8. Molecular formula: C12H14O5. Mole weight: 238.24.
1,10-Phenanthroline monohydrochloride monohydrate
1,10-Phenanthroline monohydrochloride monohydrate is a herterocyclic compound with antimycotic and anticancer properties. Synonyms: 1,10-phenanthroline hydrochloride hydrate; 1,10-Phenanthroline, hydrochloride, hydrate (1:1:1); o-Phenanthroline monohydrochloride monohydrate. Grade: ≥95%. CAS No. 18851-33-7. Molecular formula: C12H8N2.HCl.H2O. Mole weight: 234.68.
11-Deacetoxywortmannin
11-Deacetoxywortmannin is an antibiotic produced by Aspergillus janus NRRL 3807 and Penicillum funiculosum NRRL 3363. It has a strong anti-fungal and anti-inflammatory effect, and has an anti-edema effect. Synonyms: 11-Desacetoxywortmannin. CAS No. 31652-69-4. Molecular formula: C21H22O6. Mole weight: 370.39.
11-Demethyltomaymycin
11-Demethyltomaymycin is an antibiotic produced by Streptomyces achromogenes var. tomayrnyceticus. Antiviral. Synonyms: 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 2-ethylidene-1,2,3,10,11,11a-hexahydro-8,11-dihydroxy-7-methoxy-. CAS No. 55511-85-8. Molecular formula: C15H18N2O4. Mole weight: 290.31.
11-Deoxy-13-deoxodaunorubicin
11-Deoxy-13-deoxodaunorubicin is an anthracycline antibiotic produced by Micromonospora peucetica B211 F.I. It has anti-gram-positive bacteria, negative bacteria and tumor activity. CAS No. 71800-92-5. Molecular formula: C27H31NO8. Mole weight: 497.54.
11-Deoxy-13-dihydrodaunorubicin
11-Deoxy-13-dihydrodaunorubicin is an anthracycline antibiotic produced by Microjnonospora peucetica B211 F. I. It has anti-gram-positive bacteria, negative bacteria and tumor activity. CAS No. 71800-90-3. Molecular formula: C27H31NO9. Mole weight: 513.54.
11-Hydroxynovobiocin
11-Hydroxynovobiocin is a novobiocin homolog produced by Sebekia benihana UC 5762 (NRRL 11111). It has anti-gram-negative bacteria effect, and its activity is equivalent to 30% of novobiocin. Molecular formula: C31H36N2O12. Mole weight: 628.62.
11-Keto-9(E),12(E)-octadecadienoic acid
11-Keto-9(E),12(E)-octadecadienoic acid is originally isolated from Trichoderma sp. F5594. It can enhance the fibrinolytic activity of endothelial cells. Molecular formula: C18H30O3. Mole weight: 294.43.
11-O-Methylpseurotin A
11-O-Methylpseurotin A is a fungal metabolite originally isolated from Sporothrix sp. It decreases survival of hof1δ mutant strains of S. cerevisiae. Synonyms: (5S,8S,9R)-8-Benzoyl-9-hydroxy-2-[(1S,2S,3Z)-1-hydroxy-2-methoxy-3-hexen-1-yl]-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione. Grade: ≥98%. CAS No. 956904-34-0. Molecular formula: C23H27NO8. Mole weight: 445.46.
1,2,4-Trihydroxybenzene, a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes. It is a common intermediate in the biodegradation of many aromatic compounds. Synonyms: 1,2,4-Trihydroxybenzene; 2,5-Dihydroxyphenol; 2-Hydroxy-1,4-hydroquinone; 2-Hydroxy-p-benzohydroquinone; 2-Hydroxyhydroquinone; 4-Hydroxycatechol; HHQ; Hydroxyhydroquinone; NSC 2818. Grade: ≥98%. CAS No. 533-73-3. Molecular formula: C6H6O3. Mole weight: 126.11.
12-Hydroxy-6-epi-albrassitriol
12-Hydroxy-6-epi-albrassitriol is produced from cultures of Aspergillus sp. Synonyms: 6-epi-12-Hydroxyalbrassitriol; 1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-1,4-dihydroxy-5,5,8a-trimethyl-, [1S-(1α,4β,4aα,8aβ)]-; 1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-1,4-dihydroxy-5,5,8a-trimethyl-, (1S,4R,4aS,8aS)-. Grade: 98.0%. CAS No. 178330-78-4. Molecular formula: C15H26O4. Mole weight: 270.36.
1-(3,4-Dichlorophenyl)-3-(thiazol-2-yl)thiourea
It is a thiourea derivative synthesized from 1,3-thiazole. It inhibits biofilm formation in wild type and methicillin-resistant strains of staphylococcus epidermidis. Synonyms: 1-(3,4-Dichlorophenyl)-3-(2-thiazolyl)thiourea. Grade: ≥95%. Molecular formula: C10H7Cl2N3S2. Mole weight: 304.22.
1,3,6-Tri-O-methylarthothelin
4,5-Dichloro-6-O-Methylnorlichexanthone is a xanthone compound derived from Australian lichen. Molecular formula: C17H13Cl3O5. Mole weight: 403.6.
It is a halogen-containing thiourea derivative synthesized from 1,3-thiazole. It inhibits biofilm formation in wild type and methicillin-resistant strains of staphylococcus epidermidis. Synonyms: 1-(3-Chloro-4-fluorophenyl)-3-(2-thiazolyl)thiourea. Grade: ≥95%. Molecular formula: C10H7ClFN3S2. Mole weight: 287.76.
1,3-Diphenethylurea
N,N'-Diphenylethylurea is a phenylalanine metabolite isolated from marine Streptomyces. Synonyms: N,N'-bis(2-phenylethyl)urea; N,N'-Diphenethylurea; N,N'-Bis(phenethyl)urea; N-(2-phenylethyl)[(2-phenylethyl)amino]carboxamide; Glimepiride Impurity 40. Grade: ≥ 95 %. CAS No. 5467-84-5. Molecular formula: C17H20N2O. Mole weight: 268.35.
13-Hydroxyglucopiericidin A
13-Hydroxyglucopiericidin A is an antibiotic produced by Streptomyces sp. OM-5689. It has strong anti-tumor cell activity. CAS No. 132150-13-1. Molecular formula: C31H47NO10. Mole weight: 593.70.
14α-Hydroxypaspalinine is a secondary metabolite of indole isolated from Aspergillus niger. 14-α-hydroxypaspalinine is a member of the paspalinine-causing toxin family and is usually related to the toxicity of animals to pasture. Synonyms: Hydroxypaspalinine, 14-alpha-. Grade: >95% by HPLC. CAS No. 151341-77-4. Molecular formula: C27H31NO5. Mole weight: 449.54.
1,4-Diaminobutane dihydrochloride
It is an NMDA receptor agonist produced by the breakdown of amino acids after the death of an organism. It is a polyamine plant growth regulator affecting the synthesis of macromolecules and the development of root systems in plants. Uses: Used in biochemical research. Synonyms: 1,4-Butanediamine Dihydrochloride; Putrescine Dihydrochloride; Putrescine Hydrochloride; Tetramethylenediamine Dihydrochloride. Grade: ≥ 98 %. CAS No. 333-93-7. Molecular formula: C4H12N2.2HCl. Mole weight: 161.07.
14-O-Acetylindolactam V
14-O-Acetylindolactam V is an antibiotic isolated from the Actinomyces NA34-17. 14-O-Acetylindolactam V has the effect of inducing early Epstein-Barr virus antigen. Synonyms: 2S)-1-Methyl-5alpha-(acetoxymethyl)-2beta-isopropyl-1,2,4,5,6,8-hexahydro-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonine-3-one; [(2S,5S)-1-methyl-3-oxo-2-(propan-2-yl)-2,3,4,5,6,8-hexahydro-1H-[1,4]diazonino[7,6,5-cd]indol-5-yl]methyl acetate. CAS No. 91403-61-1. Molecular formula: C19H25N3O3. Mole weight: 343.42.
15-Acetoxyscirpenol is a trichothecene mycotoxin isolated from predominantly. Synonyms: MAS; 15-Monoacetoxyscirpenol; 15-Deacetylanguidin; 4-Deacetylanguidin; YD0111000; 15-Mono-O-acetylscirpenol; Trichothec-9-ene-3-alpha,4-beta,15-triol, 12,13-epoxy-, 15-acetate. CAS No. 2623-22-5. Molecular formula: C17H24O6. Mole weight: 324.37.
15-Acetyl-DON
15-Acetyl-DON is a mycotoxin produced by the fungi Fusarium culmorum and Fusarium graminearum. It can inhibit protein synthesis. Synonyms: (3α,7α)-15-(Acetyloxy)-12,13-epoxy-3,7-dihydroxy-trichothec-9-en-8-one; 15-Acetylvomitoxin; 15-O-Acetyl-4-deoxynivalenol; Deoxynivalenol 15-Acetate; 15-Acetyl Deoxynivalenol; 15-Acetoxy-3alpha,7alpha-dihydroxy-12,13-epoxytrichothec-9-en-8-one; (3alpha,7alpha)-15-(acetyloxy)-12,13-epoxy-3,7-dihydroxytrichothec-9-en-8-one. Grade: ≥98%. CAS No. 88337-96-6. Molecular formula: C17H22O7. Mole weight: 338.35.
15-Deoxy-15-oxolankamycin
It is produced by the strain of Streptomyces violaceoniger. 15-Deoxy-15-oxolankamycin has a weak anti-gram-positive effect, with anti-Staphylococcus aureus activity equal to half that of Lankamycin. Molecular formula: C42H70O16. Mole weight: 830.99.
15-Deoxyspergualin
It is produced by the strain of Bacillus laterosporus. 15-Deoxyspergualin has anti-tumor and immunosuppressive effects and is used for kidney transplantation and autoimmune diseases. Synonyms: Gusperimus; Deoxyspergualin. Grade: >98%. CAS No. 98629-43-7. Molecular formula: C17H37N7O3. Mole weight: 387.52.
1,5-Dideoxy-1,5-imino-D-mannitol
It is produced by the strain of Streptomyces lavendulae GC-148. Synonyms: (-)-1-Deoxynojirimycin. CAS No. 146747-37-7. Molecular formula: C6H13NO4. Mole weight: 163.17.
16,17-Dehydrorifamycin G is an antibiotic produced by Nocardia mediterranei R-21 (DSM 1415). It has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity. Molecular formula: C36H45NO12. Mole weight: 683.74.
16,17-Dihydrorifamycin S
Produced by the strain of Nocardia mediterranei T101. It has anti-gram-negative bacterial activity. CAS No. 51874-02-3. Molecular formula: C37H47NO12. Mole weight: 697.77.
It is produced by the strain of Streptosporangium sp. 1656. It has weak anti-fungal and anti-yeast activity. Synonyms: 1,6-Phenazinediol, 2-chloro-; 7-chloro-6-hydroxy-5H-phenazin-1-one; 7-chloro-6-hydroxyphenazin-1(5H)-one. Grade: >95%. CAS No. 93768-40-2. Molecular formula: C12H7N2O2Cl. Mole weight: 246.65.
1,6-Dihydroxyphenazine
It is produced by the strain of Streptomyces thioluteus M6-62a. It mainly has the antifungal effect, also has the inhibitory effect against the human type tuberculosis bacillus. Synonyms: 1,6-Phenazinediol; 6-hydroxyphenazin-1(5h)-one; 6-hydroxy-5H-phenazin-1-one; 2,5-diMethoxylnaphthalene. Grade: ≥95%. CAS No. 69-48-7. Molecular formula: C12H8N2O2. Mole weight: 212.20.
1,6-Dimethoxy-phenazine
It is a simple phenazine produced by several species of streptomyces. It is a weakly active antibacterial metabolite with activity against Sarcina lutea and mycobacteria. Dimethoxyphenazine and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives. Synonyms: Crystalloiodinine B. Grade: >98% by HPLC. CAS No. 13398-79-3. Molecular formula: C14H12N2O2. Mole weight: 240.26.
16-Hydroxyroridin L-2
16-Hydroxyroridin L-2 is a trichothecene group antibiotic produced by Myrothecium roridum CL-514.2. It is a mycotoxin with anti-tumor activity. CAS No. 87292-18-0. Molecular formula: C29H38O10. Mole weight: 546.60.
16-Methyloxazolomycin
16-Methyloxazolomycin is an antimicrobial and cytotoxic antibiotic produced by a Streptomyces sp. Synonyms: 16R-Methyloxazolomycin. Molecular formula: C36H51N3O9. Mole weight: 669.80.
17-Hydroxy-18-dehydroneogrifolin is isolated from the edible bodies of the mushroom Albatrellus confluens. Synonyms: 1,3-Benzenediol, 4-[(2E,6E,10S)-10-hydroxy-3,7,11-trimethyl-2,6,11-dodecatrien-1-yl]-5-methyl-; (S)-17-Hydroxy-18,20-ene-neogrifolin. Grade: 96.0%. CAS No. 1630936-42-3. Molecular formula: C22H32O3. Mole weight: 344.49.
17-O-Demethylgeldanamycin is an ansa antibiotic produced by Streptomyces hygroscopicus B-434. Anti-tumor activity. Synonyms: 17-Desmethylgeldanamycin; Des-O-methylgeldanamycin; 17-Des-O-methylgeldanamycin. CAS No. 52762-28-4. Molecular formula: C28H38N2O9. Mole weight: 546.61.
18-Norkaur-16-en-3-one. CAS No. 100227-34-7. Molecular formula: C19H28O. Mole weight: 272.42.
19,20-Epoxycytochalasin C
It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro and inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum. Synonyms: (3S,3aR,4E,7S,9R,9aR,10aS,11S,11aR,14S,14aR)-11-(acetyloxy)-6,7,9,9a,10a,11,14,14a-octahydro-3,9-dihydroxy-1,2,7,9-tetramethyl-14-(phenylmethyl)-3H-oxireno[9,10]cycloundec[1,2-d]isoindole-8,12(3aH,13H)-dione. Grade: >99% by HPLC. CAS No. 189351-79-9. Molecular formula: C30H37NO7. Mole weight: 523.62.
19,20-Epoxycytochalasin D
It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum. Synonyms: (1S,3S,3aR,4E,7S,9R,9aR,10aS,11S,11aR,14S,14aR)-11-(Acetyloxy)-3,3a,6,7,9,9a,10a,11,14,14a-decahydro-3,9-dihydroxy-1,7,9-trimethyl-2-methylene-14-(phenylmethyl)-1H-oxireno[9,10]cycloundec[1,2-d]isoindole-8,12(2H,13H)-dione; [1aS-(1aR*,2R*,2aS*,5R*,5aS*,6R*,8R*,8aS*,9E,12R*,14S*,14aS*)]-2-(Acetyloxy)-5,5a,6,7,8,8a,11,12,14,14a-decahydro-8,14-dihydroxy-6,12,14-trimethyl-7-methylene-5-(phenylmethyl)-2H-oxireno[9,10]cycloundec[1,2-d]isoindole-3,13(1aH,4H)-dione. Grade: >99% by HPLC. CAS No. 191349-10-7. Molecular formula: C30H37NO7. Mole weight: 523.62.
19-epi Tacrolimus is an impurity of Tacrolimus. Tacrolimus is an immunosuppressant that can inhibit the activity of FK-506 binding protein. Grade: ≥90% by HPLC. Molecular formula: C43H69NO12. Mole weight: 792.01.
1-Cyclohexyl-3-(1,3-thiazole-2-yl)thiourea
It is a thiourea derivative synthesized from 1,3-thiazole. It has activity against HIV-1 and CVB-5 virus. Synonyms: 1-Cyclohexyl-3-(2-thiazolyl)thiourea; 1-cyclohexyl-3-(thiazol-2-yl)thiourea; (cyclohexylamino)(1,3-thiazol-2-ylamino)methane-1-thione. Grade: ≥95%. CAS No. 71071-22-2. Molecular formula: C10H15N3S2. Mole weight: 241.38.
1-Deamino-1-hydroxysagamicin
1-Deamino-1-hydroxysagamicin is an aminoglycoside antibiotic produced by micromonospora sagarmiensis SU-2 (KY11509). It has anti-gram-positive and negative bacteria activity. Synonyms: SU-3. CAS No. 72614-86-9. Molecular formula: C20H40N4O8. Mole weight: 464.55.
(1'E)-Dechloromycorrhizin A
(1'E)-Dechloromycorrhizin A is an antibiotic produced by Lachnum papyraceum. It has weak anti-gram-positive bacteria, yeast, and mold activity, and has a strong nematicidal effect. Synonyms: (+)-Dechloromycorrhizin A. Molecular formula: C14H16O4. Mole weight: 248.27.