Producers of Peptide coupling reagents and amino acid protecting groups. Targating to all solid-phase or solution-phase peptide synthesis, utilizes Boc, CBZ, PNZ or Fmoc chemistry.
| Product | Description | |
|---|---|---|
| 1-[2-(Dimethylamino) ethyl]-1H-tetrazole-5-thiol | 1-[2-(Dimethylamino)ethyl]-1H-tetrazole-5-thiol. Group: Tetrazole Derivatives. Alternative Names: C5H11N5S. CAS No. 61607-68-9. |  Luxembourg Bio Technologies |
| 1-(3-Dimethylaminopropyl) -3-ethylcarbodiimide | 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide. Group: Carbodiimide Derivatives. Alternative Names: C8H7N3. CAS No. 1892-57-5. | Luxembourg Bio Technologies |
| 1-[3-(Dimethylamino) propyl]-3-ethylcarbodiimide methiodide | 1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide. Group: Carbodiimide Derivatives. Alternative Names: C9H20IN3. CAS No. 22572-40-3. | Luxembourg Bio Technologies |
| 1,3-Di-tert-butylcarbodiimide | 1,3-Di-tert-butylcarbodiimide. Group: Carbodiimide Derivatives. Alternative Names: C9H18N2. CAS No. 691-24-7. | Luxembourg Bio Technologies |
| 1,4-BDMT | Benzylic thiol scavenger used in TFA cleavages of peptide resins. Group: Thiol scavengers. Alternative Names: 1,4-Benzenedimethanethiol. CAS No. 105-09-9. | Luxembourg Bio Technologies |
| 1-Ethyl-1H-1,2,3,4-tetrazole-5-thiol | 1-Ethyl-1H-1,2,3,4-tetrazole-5-thiol. Group: Tetrazole Derivatives. Alternative Names: C3H6N4S. CAS No. 15217-53-5. | Luxembourg Bio Technologies |
| 1-{[(p-nitrobenzyl)oxy]carbonyl}-1H-benzotriazole | Protecting Groups for Amino Acid Building Blocks. Group: Protecting Groups for Amino Acid Building Blocks. Alternative Names: C14H10N4O4. CAS No. 86832-06-6. | Luxembourg Bio Technologies |
| 1-tert-Butyl-3-ethylcarbodiimide | 1-tert-Butyl-3-ethylcarbodiimide. Group: Carbodiimide Derivatives. Alternative Names: C7N2H14. CAS No. 1433-27-8. | Luxembourg Bio Technologies |
| 5-(Benzylthio)-1H-tetrazole | 5-(Benzylthio)-1H-tetrazole. Group: Tetrazole Derivatives. Alternative Names: C8H8N4S. CAS No. 21871-47-6. | Luxembourg Bio Technologies |
| 6-Cl-HOBt | Reagent in peptide synthesis, has also been introduced into solid-phase synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 6-Chloro-1-hydroxybenzotriazole. CAS No. 26198-19-6. | Luxembourg Bio Technologies |
| 6-Cl-HOBt in AcN | Designed to limit epimerization and increase efficiency during peptide synthesis and to ensure easy of use and safe shipping. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 6-Cl-Hydroxybenzotriazole in Acetonitrile. CAS No. 26198-19-6. | Luxembourg Bio Technologies |
| 6-Cl-HOBt in DMF | Designed to limit epimerization and increase efficiency during peptide synthesis and to ensure easy of use and safe shipping. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 6-Cl-Hydroxybenzotriazole in N,N -Dimethylformamide. CAS No. 26198-19-6. | Luxembourg Bio Technologies |
| 6-Cl-HOBt in NMP | Designed to limit epimerization and increase efficiency during peptide synthesis and to ensure easy of use and safe shipping. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 6-Cl-Hydroxybenzotriazole in N-Methylpyrrolidone solution. CAS No. 26198-19-6. | Luxembourg Bio Technologies |
| Benzoyl isothiocyanate | Benzoyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: C8H5NOS. CAS No. 523-55-8. | Luxembourg Bio Technologies |
| CDMT | It is a stable, crystalline compound, with good solubility in organic solvents, and is commercially available in large quantities. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 2-Chloro-4,6-dimethoxy-1,3,5-triazine. CAS No. 3140-73-6. | Luxembourg Bio Technologies |
| COMU® | Fast coupling efficiency, very low or non-existent tendencies for racemization. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: (1-Cyano-2-ethoxy-2-Oxoethylidenaminooxy) Dimethylamino-morpholino-carbenium hexafluorophosphate. CAS No. 1075198-30-9. registered patent of Luxembourg Bio Technologies. | Luxembourg Bio Technologies |
| Cyclohexyl isothiocyanate | Cyclohexyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: C6H11NCS. CAS No. 1122-82-3. | Luxembourg Bio Technologies |
| DCI | DCI Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 4,5- Dicyanoimidazole. CAS No. 1122-28-7. | Luxembourg Bio Technologies |
| DIC | Advantage over N,N-Dicyclohexylcarbodiimide in solid phase peptide syntheses that the urea by-product is more soluble in organic solvents and hence more readily separated from the polymer support. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: N,N-Diisopropylcarbodiimide. CAS No. 693-13-0. | Luxembourg Bio Technologies |
| DMT-Cl | Used in the coupling stage of nucleoside (hydroxyl protecting agent). Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 4,4?-Dimethoxytrityl chloride. CAS No. 40615-36-9. | Luxembourg Bio Technologies |
| EDC·HCl | EDC·HCl, usually known as water soluble carbodiimide, is a versatile modern coupling agent. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1-Ethyl-3-(3-Dimethyllaminopropyl) Carbodiimide hydrochloride. CAS No. 25952-53-8. | Luxembourg Bio Technologies |
| Ethoxycarbonyl isothiocyanate | Ethoxycarbonyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: SC4NO2H5. CAS No. 16182-04-0. | Luxembourg Bio Technologies |
| ETT | The convenient activator for RNA synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 5-(Ethylthio)-1H-tetrazole. CAS No. 89797-68-2. | Luxembourg Bio Technologies |
| HATU | Similar to HBTU, but reacts faster with less epimerization during coupling. Nevertheless, HATU is preferred to HBTU in most rapid coupling protocols (while it is utilized in the same manner as HBTU). Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1- [Bis (Dimethylamino) Methylene] -1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate. CAS No. 148893-10-1. | Luxembourg Bio Technologies |
| HBTU | HBTU is coupling reagent for peptide synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: N-[(1H-benzotriazol-1-Yl) (Dimethylamino) Methylene] -N-methylmethanaminium hexaflourophosphate N-oxide. CAS No. 94790-37-1. | Luxembourg Bio Technologies |
| HCTU | Aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superior results to TBTU in the synthesis of difficult peptides, in hindered couplings, and cyclizations. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. | Luxembourg Bio Technologies |
| HDMA | Increased coupling efficiency and lower racemization compared to HATU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1- [ (Dimethylamino) (Morpholino) Methylene] -1H-[1,2,3]triazolo[4,5-b]pyridine-1-ium 3-oxide hexafluorophosphate. CAS No. 958029-37-3. Registered patent of Luxembourg Bio Technologies. | Luxembourg Bio Technologies |
| HDMC | Aminium-type coupling reagent derived from dimethylmorpholino urea. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 6-chloro-1- ( (Dimethylamino) (Morpholino) -methylene)-1H-benzotriazolium hexafluorophosphate 3-oxide. CAS No. 1082951-62-9. Registered patent of Luxembourg Bio Technologies. | Luxembourg Bio Technologies |
| HOBt Hydrate | Developed by W. König and R. Geiger in 1970 was the most popular additive during the last decades. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Hydroxybenzotriazole hydrate. CAS No. 123333-53-9. | Luxembourg Bio Technologies |
| HOBt Hydrate in AcN | Designed to limit epimerization and increase efficiency during peptide synthesis and to ensure easy of use and safe shipping. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Hydroxybenzotriazole hydrate in AcN. CAS No. 123333-53-9. | Luxembourg Bio Technologies |
| HOBt Hydrate in DMF | Designed to limit epimerization and increase efficiency during peptide synthesis and to ensure easy of use and safe shipping. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Hydroxybenzotriazole hydrate in DMF. CAS No. 123333-53-9. | Luxembourg Bio Technologies |
| HOBt Hydrate in NMP | Designed to limit epimerization and increase efficiency during peptide synthesis and to ensure easy of use and safe shipping. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Hydroxybenzotriazole hydrate in NMP. CAS No. 123333-53-9. | Luxembourg Bio Technologies |
| HOPO | Can be used as an additive during peptide synthesis to reduce racemization and thereby increase chiral purity of the final product. Its solubility in water makes it especially useful during solution-phase peptide synthesis. HOPO has also shown to be useful in other applications, including the functionalization of self-assembled monolayers. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 2-Hydroxypyridine-N-oxide. CAS No. 13161-30-3. | Luxembourg Bio Technologies |
| i-Butyl isothiocyanate | i-Butyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: C5H9NS. CAS No. 591-82-2. | Luxembourg Bio Technologies |
| Isopropyl isothiocyanate | Isopropyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: C4H7NS. CAS No. 2253-73-8. | Luxembourg Bio Technologies |
| K-Oxyma | Potassium salt of OxymaPure, suitable coupling choice when peptides are assembled in highly acid-labile solid-supports, avoiding premature release of the peptide from the resin. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 2-Cyano-2-(hydroxyimino)acetic acid ethyl ester, potassium salt, Ethyl (hydroxyimino)cyanoacetate potassium salt. CAS No. 158014-03-0. | Luxembourg Bio Technologies |
| n-Butyl isothiocyanate | n-Butyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: CH3(CH2)3NCS. CAS No. 592-82-5. | Luxembourg Bio Technologies |
| n-Propyl isothiocyanate | n-Propyl isothiocyanate. Group: Thiocyanates Derivatives. Alternative Names: CH3CH2CH2NCS. CAS No. 628-30-8. | Luxembourg Bio Technologies |
| Oxyma-B | One of the best oxime additives currently available for racemization-free peptide synthesis. Its ability to preserve chiral purity in peptide coupling reactions exceeds that of both OxymaPure® and HOAt. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 5-(hydroxyimino)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione. CAS No. 5417-13-0. | Luxembourg Bio Technologies |
| OxymaPure® | Used with carbodiimide coupling methodology, for amide bond formation. remarkable capacity to suppress racemization and an impressive coupling efficiency in both automated and manual synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Ethyl (hydroxyimino) cyanoacetate, " 2-cyano-2-(hydroxyimino)acetate". CAS No. 3849-21-6. | Luxembourg Bio Technologies |
| PyAOP | A phosphonium salt derived from HOAt, is generally more efficient than BOP and PyBOP as coupling reagent. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: (7-Azabenzotriazol-1-Yloxy) Tripyrrolidinophosphonium hexafluorophosphate. CAS No. 156311-83-0. | Luxembourg Bio Technologies |
| PyBOP | Analogue of the BOP coupling reagent which does not form carcinogenic HMPA as by-product. May be used in place of BOP in peptide synthesis without loss of coupling efficiency. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: (Benzotriazol-1-Yloxy) Tripyrrolidinophosphonium hexafluorophosphate. CAS No. 128625-52-5. | Luxembourg Bio Technologies |
| PyBroP | Halogenphosphonium coupling reagent, was developed as an alternative to the BOP reagent, avoiding the release of the toxic HMPA in the activation step. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Bromo tri pyrrolidinophosphonium hexafluorophosphate. CAS No. 132705-51-2. | Luxembourg Bio Technologies |
| PyOxim® | Highly efficient coupling reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: [Ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinylphosphonium hexafluorophosphate. CAS No. 153433-21-7. | Luxembourg Bio Technologies |
| TBTU | Popular in situ activation reagents in solid and solution phase peptide synthesis. In addition to having high reactivity, TBTU have also been shown to limit enantiomerization during fragment condensation. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(Benzotriazol-1-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 125700-67-6. | Luxembourg Bio Technologies |
| TCFH | A safe, affordable reagent for ester and difficult amide synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: Chloro-N,N,N,N-tetramethylformamidinium hexafluorophosphate. CAS No. 207915-99-9. | Luxembourg Bio Technologies |
| TCTU | Used for peptide solid-phase synthesis. Suitable for automatic multiple peptide synthesizers. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 330641-16-2. | Luxembourg Bio Technologies |
| TOTU | The use of TOTU is possible both in classical peptide synthesis and in solid-phase peptide synthesis, belongs to the same family of COMU and HOTU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O- [ (Ethoxy carbonyl) Cyanomethylenamino] -N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 136849-72-4. | Luxembourg Bio Technologies |
| TPTU | Applied in large scale applications for the synthesis of Pharmaceuticals, in particular in situations where sensitive functionality is present on the coupling partners, and as a consequence, mild reaction conditions are required. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(2-Oxo-1(2H)pyridyl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 125700-71-2. | Luxembourg Bio Technologies |
| TSTU | TSTU is a peptide coupling reagent converts carboxylates to N-succinimidyl active esters. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: N,N,N?,N?-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate. CAS No. 105832-38-0. | Luxembourg Bio Technologies |
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