BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| MEK1 Derived Peptide Inhibitor 1 | It is a peptide composed of the first 13 amino acids of the human mitogen-activated protein kinase kinase-1 (MEK1). It inhibits the in vitro activation of ERK2 by MEK1. Synonyms: H-Met-Pro-Lys-Lys-Lys-Pro-Thr-Pro-Ile-Gln-Leu-Asn-Pro-OH; L-methionyl-L-prolyl-L-lysyl-L-lysyl-L-lysyl-L-prolyl-L-threonyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-asparagyl-L-proline. Grades: >98%. Molecular formula: C68H118N18O17S. Mole weight: 1491.84. |  |
| Melectin | Melectin is a novel antimicrobial peptide from the venom of the cleptoparasitic bee Melecta albifrons. Melectin not only possesses antimicrobial activity against sensitive and resistant bacteria but also shows antitumor activity. It exhibits moderate cytotoxicity. Molecular formula: C96H167N25O19S2. Mole weight: 2039.63. | |
| Membrane-Permeable Sequence, MPS | It corresponds to the membrane-permeable sequence designed from the carboxyl terminus of Gα subunits targeting G protein subunits. It is a membrane-translocating hydrophobic sequence specifically derived from the h-region of K-FGF (Kaposi fibroblast growth factor) signal peptide sequence. Synonyms: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Lys-OH. Grades: >98%. Molecular formula: C75H135N17O17. Mole weight: 1547.01. | |
| Mersacidin | Mersacidin is a type-B lantibiotic containing 3-methyllanthionine and S-(2-aminovinyl)-3-methylcysteine residues and four intra-chain thioether bridges. It is obtained from Bacillus sp. HIL Y-85,54728 and is active in vivo against methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: M87-1551; GTPL11014. Grades: >98% by HPLC. CAS No. 128104-18-7. Molecular formula: C80H120N20O21S4. Mole weight: 1826.19. | |
| Metchnikowin-2 | Metchnikowin-2 has antibacterial and antifungal activities. The source of Metchnikowin-2 is Drosophila melanogaster. | |
| (±)-Methionine | (±)-Methionine is an essential amino acid involved in various biochemical processes in humans and mammals. It is also in poultry meal as a source of nutrition. Synonyms: DL-2-Amino-4-(methylthio)butyric acid. Grades: >98%. CAS No. 59-51-8. Molecular formula: C5H11NO2S. Mole weight: 149.21. | |
| Methyl 2-(benzylamino)acetate hydrochloride | Methyl 2-(benzylamino)acetate hydrochloride (CAS# 17136-35-5 ) is a useful research chemical. Synonyms: Bzl-Gly-OMe Hydrochloride; N-benzylglycine methyl ester Hydrochloride; Glycine, N-(phenylmethyl)-, methyl ester Hydrochloride; Methyl benzylglycinate hydrochloride; n-alfa-benzyl-glycine methyl ester HCl; NSC-145674; N-(Phenylmethyl)glycine methyl ester HCl; Benzyl glycine methyl ester hydrochloride. Grades: ≥ 99 % by HPLC. CAS No. 17136-35-5. Molecular formula: C10H13NO2.HCl. Mole weight: 215.67. | |
| Methyl 4-chlorocarbonylbenzoate | Methyl 4-chlorocarbonylbenzoate, is a building block, that can be used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of benzophenone residues. and also for the synthesis of novel novel bulky hydrophobic retinoids, having therapeutic potential. Synonyms: MMT-CL; Terephthalic Acid Monomethyl Ester Chloride; Benzoic acid, 4-(chlorocarbonyl)-, methyl ester; Methyl terephthaloyl chloride; 4-Chlorocarbonylbenzoic acid methyl ester; 4-carbomethoxybenzoylchloride; methyl p-chloroformylbenzoate. Grades: 98 % (HPLC). CAS No. 7377-26-6. Molecular formula: C9H7ClO3. Mole weight: 198.60. | |
| Methyl 6-iodopicolinate | Methyl 6-iodopicolinate (CAS# 849830-15-5) is a useful research chemical. Synonyms: 6-Iodo-pyridine-2-carboxylic acid methyl ester; 6-Iodopyridine-2-carboxylic acid methyl ester. CAS No. 849830-15-5. Molecular formula: C7H6INO2. Mole weight: 263.03. | |
| Methyl L-pyroglutamate | Methyl L-pyroglutamate, renowned for its exceptional efficacy, serves as a natural compound. Elucidating its multifaceted role as a neuroprotective modality, this natural compound remarkably amplifies the abundance of neurotransmitters, namely acetylcholine, within the intricate neural terrain. Impressively, this scientific compound simultaneously empowers progressive cognitive restoration, bolstering the study against Alzheimer's disease and the age-related decay of our cognitive faculties. Synonyms: Methyl L-Pyroglutamate. Grades: ≥ 95%. CAS No. 4931-66-2. Molecular formula: C6H9NO3. Mole weight: 143.14. | |
| Methylphenyl sulfide | Methylphenyl sulfide can be used in the synthesis of methyl phenyl sulfoxide via oxidation. Synonyms: Thioanisole; PhSMe. Grades: ≥ 98 %. CAS No. 100-68-5. Molecular formula: C7H8S. Mole weight: 124.21. | |
| Meucin-24 | Meucin-24 was found in scorpion Mesobuthus eupeus. The synthetic meucin-24 inhibits the development of P. berghei ookinetes, kills intraerythrocytic P.falciparum, and is cytotoxic to the Drosophila S2 cell at micromolar concentrations. | |
| Meucin-25 | Meucin-25 was found in scorpion Mesobuthus eupeus. This synthetic cationic peptide inhibits the development of Plasmodium berghei ookinetes, kills intraerythrocytic P.falciparum, and is cytotoxic to the Drosophila S2 cell at micromolar concentrations. Synonyms: BeL-170; Non-disulfide-bridged peptide 5.2. | |
| Mfa-hst5 | Mfa-hst5 is from Macaca fascicularis and has antifungal, Candida spp. and Criptococcus spp. activities. | |
| MiAMP2b | MiAMP2b is isolated from Macadamia integrifolia and has antifungal activity. Synonyms: Vicilin-like Antimicrobial peptide 2b. | |
| Micasin | Micasin is an antibacterial peptide with potent activity against both Gram-positive and Gram-negative bacteria. Synonyms: Fungal defensin micasin; Fungal defensin-like peptide. | |
| Microbisporicin A1 | Microbisporicin A1 is isolated from Microbispora corallina and has antimicrobial activity. | |
| Microcin 7 | Microcin 7 is a small peptide produced and excreted to the culture medium by stationary-phase Escherichia coli cells harboring the pMccC7 plasmid (formerly named pRYC7). This peptide inhibited the growth of the enterobacteria phylogenetically closer to E. coli, apparently by blocking protein biosynthesis. | |
| Microcin C7 | Microcin C7 is an antibacterial peptide which is active against enterobacteria including species of Klebsiella, Salmonella, Shigella, Yersinia and Proteus, and strains of E.coli. Synonyms: MccC7. | |
| Microcin J25 | The bacteriocin microcin J25 (MccJ25) inhibits the growth of Gram-negative pathogens including Salmonella and Shigella species, and Escherichia coli. Synonyms: MccJ25. | |
| Midgut defensin | Midgut defensin is isolated from Haemaphysalis longicornis and has antibacterial activity. | |
| Misgurin | A novel antimicrobial peptide, named misgurin, was isolated and characterized from the loach (mudfish), Misgurnus anguillicaudatus. Misgurin showed a strong antimicrobial activity in vitro against a broad spectrum of microorganisms without significant hemolytic activity and was about 6 times more potent than magainin 2. Molecular formula: C106H189N41O29. Mole weight: 2501.88. | |
| MMGP1 | MMGP1 is an antifungal peptide which was found to possess potent antifungal activity against C. albicans. | |
| Modified defensin | Modified defensin is a synthetic construct peptide and has antibacterial activity. | |
| Moricin | Moricin is a novel antibacterial peptide that shows antibacterial activity against Staphylococcus aureus and it was isolated from the hemolymph of the silkworm, Bombyx mori. The peptide showed antibacterial activity against several Gram-negative and -positive bacteria and had a higher activity against Gram-positive bacteria than cecropin B1, a major antibacterial peptide of B. mori. Synonyms: Moricin-1; Moricin-2. | |
| Moricin-like peptide A | Moricin-like peptide A has antibacterial and antifungal activity. The source of Moricin-like peptide A is Galleria mellonella [Greater wax moth]. | |
| Moricin-like peptide B | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram positive bacteria and gram negative bacteria. | |
| Moricin-like peptide C1 | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram positive bacteria and gram negative bacteria. | |
| Moricin-like peptide C2 | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram positive bacteria and gram negative bacteria. | |
| Moricin-like peptide C3 | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram positive bacteria and gram negative bacteria. | |
| Moricin-like peptide C4 | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram positive bacteria and gram negative bacteria. | |
| Moricin-like peptide D | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram positive bacteria and gram negative bacteria. | |
| MPGΔNLS, HIV related | It is a 27-residue peptide derived from the hydrophobic fusion peptide of HIV-1 gp41 (for efficient crossing of the cell membrane) and the hydrophilic nuclear localization sequence of SV40 large T antigen (for the nuclear addressing of the peptide). It contains a single mutation in which the second lysine in NLS has mutated to serine. Synonyms: H-Gly-Ala-Leu-Phe-Leu-Gly-Phe-Leu-Gly-Ala-Ala-Gly-Ser-Thr-Met-Gly-Ala-Trp-Ser-Gln-Pro-Lys-Ser-Lys-Arg-Lys-Val-OH. Grades: 97%. Molecular formula: C126H201N35O33S. Mole weight: 2766.27. | |
| Mp_mastoparan MP | Mp_mastoparan MP was found in Venom, wasps, Mischocyttarusphthisicus. Mp_mastoparan MP has antimicrobial activity. | |
| MPS-Gαi3 | It is a cell penetrating peptide. Synonyms: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Lys-Asn-Asn-Leu-Lys-Glu-Cys-Gly-Leu-Tyr-OH. Grades: >95%. Molecular formula: C120H205N29O31S. Mole weight: 2582.19. | |
| MP-VB1 | MP-VB1 showed strong antimicrobial activities against bacteria and fungi and induced mast cell degranulation, but displayed almost no hemolytic activity towards human blood red cells. | |
| MR10 | | |
| Mram 8 | Mram 8 is isolated from Viola philippica which is a plant from the Violaceae family. | |
| MSI-594 | MSI-594 is a highly active AMP with a broad-spectrum of activities against bacteria, fungi, and virus. | |
| M-theraphotoxin-Gr1a | This cationic hydrophobic peptide inhibits a lot of different channels and has an antimicrobial activity. It also exhibits antimicrobial activities against the Gram-positive bacteria B.subtilis (MIC=0.5 μM), S.aureus (MIC=2-4 μM), and S.epidermidis (MIC=4-8 μM), and Gram-negative bacteria S.typhimurium (MIC=32.64 μM), P.aeruginosa (MIC=8-16 μM), and E.coli (MIC=8-16 μM). Synonyms: M-TRTX-Gr1a; GsMTx-4. | |
| Mucroporin | Mucroporin is a cationic host defense peptide that has antibacterial activity by breaking membranes. Mucroporin is more effective on Gram-positive than on Gram-negative bacteria. Synonyms: Antimicrobial peptide 36.21; Non-disulfide-bridged peptide 4.5. | |
| Mucroporin-like peptide | Mucroporin-like peptide is an antimicrobial peptide found in Lychas mucronatus (Chinese swimming scorpion), and has antibacterial activity. Synonyms: Leu-Phe-Phe-Leu-Pro-Ser-Leu-Ile-Gly-Gly-Leu-Ile-Ser-Ala-Phe-Lys; NDBP13. Grades: ≥97%. Molecular formula: C87H135N17O19. Mole weight: 1723.13. | |
| Mundticin | Mundticin is an antimicrobial peptide found in Enterococcus mundtii ATO6, and has antibacterial activity. Synonyms: Mundticin ATO6 (Bacteriocin); Mun ATO6. Grades: >85%. Molecular formula: C186H289N55O58S2. Mole weight: 4287.83. | |
| Mundticin KS | Mundticin KS is an antimicrobial peptide found in Enterococcus mundtii NFRI 7393, and has antibacterial activity. Synonyms: Mun KS. Grades: >85%. Molecular formula: C186H289N55O58S2. Mole weight: 4287.83. | |
| Murepavadin | Murepavadin is a Pseudomonas specific peptidomimetic antibiotic. CAS No. 944252-63-5. Molecular formula: C73H112N22O16. Mole weight: 1553.8. | |
| Murepavadin TFA | Murepavadin (TFA), a 14-amino acid cyclic peptide, is a highly effective, specific antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Murepavadin (TFA) targets the lipopolysaccharide transport protein D. Synonyms: POL7080 (TFA); Cyclo(Ala-Ser-d-Pro-Pro-Thr-Trp-Ile-Dab-Orn-d-Dab-Dab-Trp-Dab-Dab).TFA; Murepavadin trifluoroacetic acid. Grades: >98%. Molecular formula: C73H112N22O16.C2HF3O2. Mole weight: 1667.83. | |
| Mussel Defensin MGD-1 | Mussel Defensin MGD-1 is an antimicrobial peptide found in Mediterranean mussel, Mytilus galloprovincialis. It has activity against gram-positive bacteria. Synonyms: MGD1 antimicrobial peptide; Mediterranean mussel defensin 1. Grades: >85%. | |
| Mussel defensin MGD-2 | Mussel defensin MGD-2 is an antimicrobial peptide found in Mediterranean mussel, Mytilus galloprovincialis, and has antibacterial and antifungal activity. Synonyms: MGD2 antimicrobial peptide; Mediterranean mussel defensin 2. Grades: >85%. | |
| Mutacin 1140 | Mutacin 1140 is an antimicrobial peptide found in Streptococcus mutans, and has antibacterial activity against a broad spectrum of Gram-positive bacteria. Synonyms: MU1140; L-Phenylalanyl-L-lysyl-D-cysteinyl-L-tryptophyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-(2S)-2-amino-3-mercaptobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-arginyl-(2Z)-2-amino-2-butenoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-[(1Z)-2-mercaptoethenyl]-L-cysteinamide, cyclic (3-7),(8-11),(16-213),(19-211)-tetrakis(thioether); Lantibiotic mutacin-1140; lanA; Mutacin III. Grades: >85%. CAS No. 218133-96-1. Molecular formula: C103H138N28O23S4. Mole weight: 2264.65. | |
| Mutacin IV | Mutacin IV is an antimicrobial peptide found in Streptococcus mutans UA140, and has antibacterial activity. Mutacin IV is a nonlantibiotic bacteriocin encoded by the nlm operon, which contains two genes, nlmA and nlmB, organized in tandem. Synonyms: NlmA and NlmB. Grades: >98%. | |
| Myeloid antimicrobial peptide | BMAPs (bovine myeloid antimicrobial peptides) are bovine cathelicidins that share many structural and functional features with human cathelicidin. | |
| Myeloid antimicrobial peptide BMAP-27 | BMAP-27 is a 26 amino-acid peptide with amidated C-terminus. It has shown potent antimicrobial effects against various species of bacteria and parasites. BMAP-27 was the most effective at killing Staphylococcus aureus, Streptococcus uberis, and Escherichia coli, and this was dependent on its amphipathic structure and cationic charge. However, it seems to have hemolytic effects on cultured blood cells, as well as cytotoxic effects to hematopoietic cells and activated human lymphocytes. | |
| Myeloid antimicrobial peptide BMAP-28 | A bovine myeloid antimicrobial peptide (BMAP-28) belongs to the cathelicidin family and exerts potent antimicrobial activity in order to protect animals from bacterial and fungal infections. Moreover, it has been indicated that the antimicrobial effect of BMAP-28 can be enhanced by altering its cationic and hydrophobic amino acid residues. | |
| Myeloid cathelicidin 1 | Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Synonyms: CATH-1 protein; CAP18; eCATH-1. | |
| Myeloid cathelicidin 2 | Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Synonyms: eCATH-2. | |
| Myeloid cathelicidin 3 | Cathelicidin-derived antimicrobial peptides are a component of the peptide-based host defense of neutrophils and epithelia, with a widespread distribution in mammals. A broad spectrum of antimicrobial activity was demonstrated for eCATH-1 and eCATH-3, while the equine cathelicidin, eCATH-2 had antibacterial activity restricted to E. coli, S. aureus. Furthermore, eCATH-3 showed potent activity against some fungi like C. neoformans and Rhodotorula rubra, but its activity depends on the salt concentration being strongly inhibited at the physiological salt concentration. Synonyms: eCATH-3. | |
| Myrcludex B atto | An atto-dye-labeled MyrB (Myrcludex B). Myrcludex B is an inhibitor of HBV and HDV infections. Synonyms: MyrB-atto. Grades: 95%. | |
| Myticin C | Myticins, antimicrobial peptides that have been previously characterized, were constitutively expressed in a fraction of mussel hemocytes and showed antiviral activity against OsHV-1. Moreover, myticin C peptides showed antiviral activity against human herpes simplex viruses 1 (HSV-1) and 2 (HSV-2). Synonyms: Myt C. | |
| Mytilus defensin | MGD1 (Mytilus galloprovincialis defensin 1), a new member of the arthropod defensin family, is a 4 kDa antibacterial peptide previously isolated from the plasma of Mediterranean mussels. Its biological activity is directed against both gram-positive and gram-negative bacteria but it is not cytotoxic towards human erythrocytes nor protozoa. Synonyms: MGD-1; Mytilus galloprovincialis defensin 1. | |
| Mytilusl defensin | Mytilusl defensin has antimicrobial activities. Synonyms: mytilin. | |
| Mytimycin | The antifungal peptide mytimycin (MytM) is synthesized by hemocytes of the Mediterranean mussel, Mytilus galloprovincialis. Synonyms: MytM. | |
| Myxinidin | Myxinidin, a novel antimicrobial peptide from the epidermal mucus of hagfish, Myxine glutinosa L. Myxinidin showed activity against a broad range of bacteria and yeast pathogens at minimum bactericidal concentration (MBC) ranging from 1.0 to 10.0 microg/mL. | |
| N1-Boc-N4-Fmoc-piperazine-2-carboxylic acid | Synonyms: 4-FMOC-1-BOC-PIPERAZINE-2-CARBOXYLIC ACID; 1-N-BOC-4-N-FMOC-PIPERAZINE-2-CARBOXYLIC ACID; 1-(TERT-BUTOXYCARBONYL)-4-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-2-PIPERAZINECARBOXYLIC ACID; 1-BOC-4-FMOC-PIPERAZINE-2-CARBOXYLIC ACID; N-1-BOC-N-4-FMOC-2-PIPERAZINE CARBO. Grades: ≥ 98% (Assay). CAS No. 218278-58-1. Molecular formula: C25H28N2O6. Mole weight: 452.5. | |
| N1,N5-Bis-Boc-spermidine | Synonyms: 1,6-Bis-Boc-1,6,10-triazadecane. Grades: ≥ 99% (HPLC). CAS No. 68076-39-1. Molecular formula: C17H35N3O4. Mole weight: 345.5. | |
| N-(2,4-Dinitrophenyl)-L-proline | Synonyms: Dnp-Pro-OH; (S)-1-(2,4-Dinitrophenyl)pyrrolidine-2-carboxylic acid. CAS No. 1655-55-6. Molecular formula: C11H11N3O6. Mole weight: 281.22. | |
| N-[2-(Boc-amino)ethyl]glycine ethyl ester hydrochloride | Synonyms: N-(Boc-aminoethyl)-Gly-OEt HCl; Ethyl [2-(Boc-amino)ethylamino]acetate hydrochloride; Ethyl N-[(2-Boc-amino)ethyl]glycinate hydrochloride. Grades: ≥ 97% (NMR). CAS No. 347890-34-0. Molecular formula: C11H22N2O4·HCl. Mole weight: 282.76. | |
| N- (2-Chlorobenzyloxycarbonyloxy) succinimide | This reagent is used to introduce the 2-chloro-Z group for protection of the side chain function of lysine. Synonyms: Z(2-Cl)-OSu; 2-Chlorobenzyl succinimidyl carbonate; 2,5-Pyrrolidinedione, 1-[[[(2-chlorophenyl)methoxy]carbonyl]oxy]-; 2,5-dioxoazolidinyl [(2-chlorophenyl)methoxy]formate. Grades: ≥ 99% (HPLC). CAS No. 65853-65-8. Molecular formula: C12H10ClNO5. Mole weight: 283.66. | |
| N-[3-(2-Furyl)acryloyl]succinimide | Synonyms: Furacryl-OSu; FA-OSu. Grades: 99%. CAS No. 56186-54-0. Molecular formula: C11H9NO5. Mole weight: 235.20. | |
| N-(3-Hydroxypropyl)trifluoroacetamide | N-(3-Hydroxypropyl)trifluoroacetamide (CAS# 78008-15-8) is a useful research chemical compound. Synonyms: Tfa-β-Ala-ol; Tfa-NH-(CH2)3-OH; N-Trifluoroacetyl-β-alaninol; 3-[(Trifluoroacetyl)amino]-1-propanol; 2,2,2-trifluoro-N-(3-hydroxypropyl)acetamide; N-(3-hydroxypropyl)-2,2,2-trifluoroacetamide. CAS No. 78008-15-8. Molecular formula: C5H8F3NO2. Mole weight: 171.13. | |
| N4-Fmoc-piperazine-2-carboxylic acid | Synonyms: N4-Fmoc-Piz-2-carboxylic acid. Grades: ≥ 95% (HPLC). CAS No. 219312-90-0. Molecular formula: C20H22N2O4. Mole weight: 352.388. | |
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