BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| UV Cleavable Biotin-PEG2-alkyne | UV Cleavable Biotin-PEG2-alkyne contains a UV cleavable fragemnt, the reagent is reactive with azide containing molecule via click chemistry. Please contact us for GMP-grade inquiries. Synonyms: Azido-C3-UV-biotin; UV Cleavable Biotin-PEG2-Alkyne; AKOS040742953; BP-22689; HY-140927; CS-0115915; [1-[3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]phenyl]-2-oxo-2-phenylethyl] hex-5-ynoate; 1-(3-((2,13-Dioxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9-dioxa-3,12-diazaheptadecyl)oxy)phenyl)-2-oxo-2-phenylethyl hex-5-ynoate. Grade: 0.98. Molecular formula: C38H48N4O9S. Mole weight: 736.9. |  |
| UV Cleavable Biotin-PEG2-Azide | UV Cleavable Biotin-PEG2-Azide is a biotin linker. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound. Captured target can be released under mild photolysis conditions (365 nm) and results in a significant decrease of background signal due to non-specifically bound proteins. Please contact us for GMP-grade inquiries. Synonyms: [2-[2-[2-[2-[2-[5-[(3aS,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]-6-phenacylphenyl] 6-azidohexanoate; 1654739-36-2. Grade: 0.98. CAS No. 1654739-36-2. Molecular formula: C38H51N7O9S. Mole weight: 781.9. | |
| V5 Epitope Tag Peptide | V5 Epitope Tag Peptide, a tag peptide derived from a small epitope present on the P and V proteins of the paramyxovirus of simian virus 5, is used as a blocking peptide in WB or ELISA for the V5 Epitope tag antibody. Synonyms: H-Gly-Lys-Pro-Ile-Pro-Asn-Pro-Leu-Leu-Gly-Leu-Asp-Ser-Thr-OH; L-Threonine, glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-prolyl-L-asparaginyl-L-prolyl-L-leucyl-L-leucylglycyl-L-leucyl-L-α-aspartyl-L-seryl-; Glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-prolyl-L-asparaginyl-L-prolyl-L-leucyl-L-leucylglycyl-L-leucyl-L-α-aspartyl-L-seryl-L-threonine. Grade: ≥95%. CAS No. 141074-86-4. Molecular formula: C64H108N16O20. Mole weight: 1421.64. | |
| Valerenic acid | Valerenic acid is a positive allosteric modulator of GABAA receptors displaying selectivity for receptors containing β2 or β3 subunits. Valerenic acid exhibits sedative, anticonvulsant and anxiolytic effects in vivo. Valerenic acid also acts as a partial agonist of 5-HT5A receptors. Synonyms: valerinic acid; (-)-valerenic acid. Grade: ≥99% by HPLC. CAS No. 3569-10-6. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Validamycin A | The major analogue of a family of cyclitol disaccharides isolated from streptomyces hygroscopicus var. Limoneus. It is a potent antifungal agent used to control fungi in crop production and acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi. Synonyms: jinggangmycin; Antibiotic T 7545A. Grade: >95% by HPLC. CAS No. 37248-47-8. Molecular formula: C20H35NO13. Mole weight: 497.49. | |
| Validamycin B | Validamycin B is an impurity of Validamycin that is resistant to rice sheath blight disease and Pellicularia sasakii. Synonyms: Antibiotic T-7545-B; Val-B; (1R,2R,3S,4S,5R,6S)-2,3,5-trihydroxy-6-(hydroxymethyl)-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside; 1,5-Dideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol. CAS No. 102583-47-1. Molecular formula: C20H35NO14. Mole weight: 513.49. | |
| Validamycin C | An impurity of Validamycin. Validamycin is an antibiotic and fungicide. Synonyms: BRN 4835203; (3-{[4-(hexopyranosyloxy)-2,3-dihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-4,5,6-trihydroxycyclohex-1-en-1-yl)methyl hexopyranoside; 2-(hydroxymethyl)-6-[[3-[[5-(hydroxymethyl)-4-[6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,3-bis(oxidanyl)cyclohexyl]amino]-4,5,6-tris(oxidanyl)cyclohexen-1-yl]methoxy]oxane-3,4,5-triol. CAS No. 12650-70-3. Molecular formula: C26H45NO18. Mole weight: 659.63. | |
| Valinomycin | A hydrophobic cyclodepsipeptide with potent antitumour activity; a highly selective potassium ionophore; a biosensor to detect potassium efflux. Synonyms: Potassium ionophore I; valino; Valinomicin; NSC122023; Antibiotic N-329 B; cyclo[-D-O-Val-D-Val-L-O-Ala-L-Val]3; BRN 0078657; (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone. Grade: >95% by HPLC. CAS No. 2001-95-8. Molecular formula: C54H90N6O18. Mole weight: 1111.32. | |
| Valnemulin | Valnemulin is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. Synonyms: Econor; Biotilina. Grade: >99% by HPLC. CAS No. 101312-92-9. Molecular formula: C31H52N2O5S. Mole weight: 564.82. | |
| Valnemulin hydrochloride | The hydrochloride salt form of Valnemulin is a wide-spectrum antibiotic that has been found to have strong antibacterial activity especially against mycoplasma and spirochete, and is commonly used as a veterinary drug. It can prevent and control swine dysentery, ileitis, colitis and other intestinal diseases, as well as swine asthma and other respiratory diseases. Synonyms: Valnemulin HCl; UNII-W1GDP58BNQ; W1GDP58BNQ. Grade: >90%. CAS No. 133868-46-9. Molecular formula: C31H53ClN2O5S. Mole weight: 601.28. | |
| Valorphin | Valorphin is an endogenous hemoglobin β-chain (33-39) fragment. Valorphin has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM. Synonyms: H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH. Grade: 95%. CAS No. 144313-54-2. Molecular formula: C44H61N9O11. Mole weight: 892.01. | |
| Valorphin TFA | Valorphin TFA is an endogenous hemoglobin β-chain (33-39) fragment. It has opioid analgesic activity, and binds to rat mu-opioid receptor, with an IC50 of 14 nM. Synonyms: H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH.TFA; L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutamine trifluoroacetic acid. Grade: ≥95%. Molecular formula: C46H62F3N9O13. Mole weight: 1006.03. | |
| Val-Pro-Pro | Val-Pro-Pro is an angiotensin-converting enzyme inhibitor. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: L-Valyl-L-prolyl-L-proline; L-Proline, 1-(1-L-valyl-L-prolyl)-. Grade: >98%. CAS No. 58872-39-2. Molecular formula: C15H25N3O4. Mole weight: 311.38. | |
| Vancomycin | Tricyclic glycopeptide antibiotic. Inhibits cell wall synthesis in Gram-positive bacteria. Pharmacologically active in vivo. Synonyms: Vancocin; Vancomycinum; Vancomicina; Vancomycine; (S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-((S)-6-hydroxy-2-imino-hexahydro-pyrimidin-4-yl)-9,12-bis-hydroxymethyl-2,5,8,11,14-pentaoxo-6-[1-ureido-meth-(Z)-ylidene]-1,4,7,10,13pentaaza-cyclohexadec-15-yl}-amide. Grade: >98%. CAS No. 1404-90-6. Molecular formula: C66H75Cl2N9O24. Mole weight: 1449.25. | |
| Vancomycin EP Impurity A | Vancomycin EP Impurity A is a glycopeptide antibiotic produced by Nocardia orientalis A51568.1. Activity against gram-positive bacteria. Synonyms: N2.1-demethylvancomycin B; N-Demethyl Vancomycin B; Norvancomycin; A51568 A. Grade: 95%. CAS No. 91700-98-0. Molecular formula: C65H73Cl2N9O24. Mole weight: 1435.22. | |
| Vancomycin hydrochloride | The salt of a glycopeptide antibiotic isolated from amycolatopsis orientalis. Vancomycin hydrochloride exhibits potent activity against Gram-positive bacteria, and high effects against MRSA in vitro and in vivo. It interferes with cell wall synthesis by binding to D-alanine-D-alanine residues. Synonyms: Vancomycin HCl; Vancomycin Monohydrochloride. Grade: Assay: 900 ug/mg. CAS No. 1404-93-9. Molecular formula: C66H75Cl2N9O24.HCl. Mole weight: 1485.72. | |
| Venturicidin A | The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A1. Grade: >95% by HPLC. CAS No. 33538-71-5. Molecular formula: C41H67NO11. Mole weight: 749.97. | |
| Venturicidin B | The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A2; (1R,2E,7R,8E,10R,12R,13S,17R)-7-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-17-hydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-2,10,12,20-tetramethyl-14,21-dioxabicyclo[15.3.1]henicosa-2,8,19-trien-15-one. Grade: >95% by HPLC. CAS No. 33538-72-6. Molecular formula: C40H66O10. Mole weight: 706.94. | |
| (±)-Verapamil-[d3] HCl | One of the isotopic labelled form of (±)-Verapamil, which is a calcium channel blocker and could be used as antiarrhythmic and antihypertensive agent. Synonyms: 5-((3,4-Dimethoxyphenethyl)(methyl-d3)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile monohydrochloride. Grade: 95% by HPLC; 98% atom D. Molecular formula: C27H36D3ClN2O4. Mole weight: 494.09. | |
| Verrucarin A | It is produced by the strain of Myrothecium verrucaria NRRL 3003. Verrucarin A has the effect of anti-Gram-negative bacteria and fungi, inhibiting Newcastle disease virus, tobacco Mosaic virus, and S-37 sarcoma and Yoshida sarcoma in animals. Synonyms: Muconomycin A; Antibiotic 379Y; VER A; (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione; NSC 126728. Grade: 95%. CAS No. 3148-9-2. Molecular formula: C27H34O9. Mole weight: 502.55. | |
| Verrucarin J | Verrucarin J is produced by the strain of Myrothecium verrucaria NRRL 3003. The ED50 of Verrucarin J on giant cell tumor P-815 cells was about 0.001 μg/mL. Uses: For research used only. Synonyms: Muconomycin B; 2',3'-Didehydro-2'-deoxyverrucarin A; Verrucarin A, 2',?3'-didehydro-2'-deoxy-, (2'E)?-; Verrucrin J; Verrucosporin J. Grade: ≥98%. CAS No. 4643-58-7. Molecular formula: C27H32O8. Mole weight: 484.54. | |
| Verticillin A | Verticillin A is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: [10b,10'b(11H,11'H)-Bi-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone, 2,2',3,3',5a,5'a,6,6'-octahydro-11,11'-dihydroxy-2,2',3,3'-tetramethyl-, (3S,3'S,5aR,5'aR,10bS,10'bS,11S,11'S,11aS,11'aS)-; [10b,10'b(11H,11'H)-Bi-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone, 2,2',3,3',5a,5'a,6,6'-octahydro-11,11'-dihydroxy-2,2',3,3'-tetramethyl-, [3S-[3α,5aβ,10bβ(3'R*,5'aS*,10'bR*,11'R*,11'aR*),11β,11aα]]-; Verticillin A, (+)-; (6S,6'S)-19,19'-Dideoxy-6,6'-dihydroxychetocin. CAS No. 889640-30-6. Molecular formula: C30H28N6O6S4. Mole weight: 696.84. | |
| Verticillin C | Verticillin C is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: Verticillin C. Grade: 95%. CAS No. 51798-48-2. Molecular formula: C30H28N6O7S5. Mole weight: 744.90. | |
| Verucopeptin | It is an antibiotic produced by the strain of Actinomadura verrucosospora Q886-2. It has weak antimicrobial effect and can prolong the survival time of mice transplanted with melanoma. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Synonyms: 2-hydroxy-N-(17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl)-2-[2-hydroxy-5-methoxy-6-[(E)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide. Grade: 98%. CAS No. 138067-14-8. Molecular formula: C43H73N7O13. Mole weight: 896.08. | |
| Vidarabine | 9-β-D-Arabinof uranosyladenine is a nucleoside antibiotic produced by Streptomyces antibioticusm and Str. herbaceusm. It has a strong weeding effect on a variety of monocotyledonous and dicotyledonous plants. Synonyms: Ara-adenosine; 9-β-D-Arabinofuranosyladenine; 9-(b-D-Arabinofuranosyl)adenine; Adenine arabinoside; Arabinosyladenine; Spongoadenosine; Araadenosine; Arabinosyl adenine; (2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 9-β-D-Arabinofuranosyl-9H-purin-6-amine; Adenine Arabinofuranoside. Grade: ≥95%. CAS No. 5536-17-4. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| Violacein | It is a nitrogenous heterocyclic indole antibiotic produced by the strain of Chromobacterium violaceum. It has anti-gram-positive bacteria, fungi and protozoa effects. The serum has an effect on its activity. Synonyms: (3E)-3-[5-(5-Hydroxy-1H-indol-3-yl)-2-oxo-1,2-dihydro-3H-pyrrol-3-yliden]-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-, (3E)-. Grade: ≥ 95% (violacein and deoxyviolacein), Violacein ≥ 80%. CAS No. 548-54-9. Molecular formula: C20H13N3O3. Mole weight: 343.34. | |
| Viomycin | Tuberactinomycin B is a member of the tuberactinomycin family of antibiotics used for the treatment of multidrug-resistant tuberculosis. Tuberactinomycin B inhibits group I intron splicing and prokaryotic protein synthesis, and freezes bacterial ribosomes in either the pre-or post-translational state. Uses: The treatment of multidrug-resistant tuberculosis. Synonyms: Tuberactinomycin B; Celiomycin; Florimycin; Viomicina; Viomycine; Viomycinum. CAS No. 32988-50-4. Molecular formula: C25H43N13O10. Mole weight: 685.69. | |
| Viomycin sulfate | It is a peptide antibiotic produced by the strain of Str. puniceus 1314-5 and Str. floridae A5014. It has broad-spectrum antibacterial and strong anti-mycobacterium effect. 1-10 μg/mL of Viomycin can inhibit the growth of most tuberculosis bacilli, the main effect is to inhibit the protein synthesis of bacteria, but bacteria are prone to develop drug resistance. In clinical application, it is only used as a second-line drug to treat tuberculosis. Synonyms: Tuberactinomycin B sulfate salt; celicomycin-sulfate; florimycin sulfate; Vinacetin A sulfate; hexanamide, 3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[[(aminocarbonyl)amino]methylene]-3-[(4R,6S)-2-amino-3,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadec-15-yl]-, (3S)-, sulfate (1:1) (salt). CAS No. 37883-00-4. Molecular formula: C25H43N13O10.H2O4S. Mole weight: 783.77. | |
| VIP (6-28) (human, rat, porcine, bovine) | VIP (6-28) (human, rat, porcine, bovine) is an effective antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) on cAMP. Synonyms: Aviptadil (6-28); Vasoactive Intestinal Peptide (6-28). CAS No. 69698-54-0. Molecular formula: C126H207N37O34S. Mole weight: 2816.28. | |
| VIP Antagonist | VIP antagonist, a hybrid of neurotensin (6-11) and VIP (7-28), is a competitive antagonist of VIP-binding to glial cells. In rats with reduced masculine potency, it significantly inhibits VIP-stimulated sexual behavior. It antagonizes VIP receptors on non-small cell lung cancer cells, thereby inhibiting tumor growth in vivo and in vitro. Synonyms: [Lys1,Pro2,5,Arg3,4,Tyr6]VIP, human, porcine, rat, ovine; H-Lys-Pro-Arg-Arg-Pro-Tyr-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2; L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-threonyl-L-alpha-aspartyl-L-asparagyl-L-tyrosyl-L-threonyl-L-arginyl-L-leucyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-asparagyl-L-seryl-L-isoleucyl-L-leucyl-L-asparaginamide; [Lys1,Pro2,5,Arg3,4,Tyr6]-Vasoactive Intestinal Peptide human, porcine, rat. Grade: 95%. CAS No. 125093-93-8. Molecular formula: C154H257N49O40S. Mole weight: 3467.06. | |
| Virantmycin | It is produced by the strain of Str. nitrosporeus AM-2722. It has antiviral effect. It inhibits four RNA viruses and four DNA viruses with MIC (μg/mL) of 0.008-0.04 and 0.005-0.03, respectively. It has weak antifungal effect. Synonyms: 6-Quinolinecarboxylic acid, 3-chloro-2-(3,4-dimethyl-3-penten-1-yl)-1,2,3,4-tetrahydro-2-(methoxymethyl)-, (2R,3R)-; NSC 374127; 6-Quinolinecarboxylic acid, 3-chloro-2-(3,4-dimethyl-3-pentenyl)-1,2,3,4-tetrahydro-2-(methoxymethyl)-, (2R-cis)-; (-)-Virantmycin. Grade: 99%. CAS No. 76417-04-4. Molecular formula: C19H26C1NO3. Mole weight: 351.87. | |
| Virginiamycin | Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 (75%) and virginiamycin S1 (25%). It is an antibiotic used primarily in the treatment of staphylococcal infections, and to a less extent streptococcal infections. Uses: Anti-bacterial agents. Synonyms: Pristinamycin. CAS No. 11006-76-1. Molecular formula: C71H84N10O17. Mole weight: 1349.48. | |
| Virginiamycin B | Pristinamycin IA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Mikamycin B; Ostreogrycin B; Pristinamycin IA; Streptogramin B; Syncothrecin B1; Synergistin B; Vernamycin Balpha; Antibiotic PA 114B. Grade: 95%. CAS No. 3131-3-1. Molecular formula: C45H54N8O10. Mole weight: 866.96. | |
| Virginiamycin S1 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin S; Staphylomycin S1; Antibiotic 1754Z3B; Virginiamycin factor S; NSC177858; Stephylomycin; Eskamicin; Cebin V; Factor S; Glycine, N-[(3-hydroxy-2-pyridinyl)carbonyl]-L-threonyl-D-2-aminobutanoyl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-2-piperidinecarbonyl-L-2-phenyl-, r-lactone. Grade: >99% by HPLC. CAS No. 23152-29-6. Molecular formula: C43H49N7O10. Mole weight: 823.89. | |
| Viridicatin | It is a quinoline aromatic antibiotic produced by the strain of Pen. viridicatum, Pen. cyclopium SM-72 and Pen. puberulum. It has anti-gram-positive bacteria and mycobacteria effects. Synonyms: 2,3-dihydroxy-4-phenylquinoline; 2(1H)-Quinolinone, 3-hydroxy-4-phenyl-. Grade: >99% by HPLC. CAS No. 129-24-8. Molecular formula: C15H11NO2. Mole weight: 237.25. | |
| (?)-Viriditoxin | (-)-Viriditoxin is a mycotoxin originally isolated from A. viridinutans. Exhibits broad activity against Gram-positive bacteria. Bacterial cell division protein FtsZ inhibitor (IC50=8.2μg/ml). Inhibits the GTPase activity of FtsZ in vitro (IC50 = 7.0 μg/ml). Induces apoptosis and autophagy and inhibits cell growth at G2/M in human prostate cancer cells. Activates ATP hydrolysis and induces calcium sensitized swelling of rat liver mitochondria. Synonyms: UNII-6TAK972FMC; 6TAK972FMC. Grade: ≥98%. CAS No. 1381782-08-6. Molecular formula: C34H30O14. Mole weight: 662.59. | |
| Virstatin | Virstatin is an inhibitor of the virulence transcriptional activator ToxT of V. cholerae. It prevents expression of the two major V. cholerae virulence factors, cholera toxin (CT) and the toxin coregulated pilus, by inhibiting ToxT. Synonyms: Isodibut; 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid; 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid; 4-(N-(1,8-naphthalimide))-n-butyric acid; 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid. Grade: ≥98%. CAS No. 88909-96-0. Molecular formula: C16H13NO4. Mole weight: 283.28. | |
| Virustomycin A | Virustomycin A is a 18-membered macrolide antibiotic originally isolated from Streptomyces sp. AM-2604. It is effective against infectious and plant pathogenic fungi. It is active against trichomonads and various RNA and DNA viruses. Synonyms: AM 2604A; Antibiotic AM 2604A; [2R-[2R*[1S*[2R*,4R*,5S*,6R*(E)],2R*,3S*],3S*,4E,6E,9R*,10S*,11S*,12R*,13R*,14E,16Z]]-2-[3-(11-Ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen-2-yl)-2-hydroxy-1-methylbutyl]tetrahydro-2-hydroxy-5-methyl-6-(1-propenyl)-2H-pyran-4-yl Ester 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoic Acid; 23-O-De(4-O-aminocarbonyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-23-O-[4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,4-dioxo-2-butenyl]concanamycin A. Grade: ≥98%. CAS No. 84777-85-5. Molecular formula: C48H71NO14. Mole weight: 886.08. | |
| Vitamin D3 | Cholecalciferol is a naturally occurring form of vitamin D which is obtained from dietary sources, such as fish, or through the conversion of 7-dehydrocholesterol by ultraviolet light. It is subsequently metabolized to 25-hydroxyvitamin D3 and the active form 1,25-dihydroxyvitamin D3 by cytochrome P450 isoforms in the liver. It could prevent proliferation of cancer cells. Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; Cholecalciferol; Duphafral D3 1000; Delsterol; Deparal; Ebivit; Oleovitamin D3; Provitina; Ricketon; Vi-De3; Videkhol; Vigorsan; Vitinc Dan-Dee-3; Colecalciferol. Grade: >98%. CAS No. 67-97-0. Molecular formula: C27H44O. Mole weight: 384.64. | |
| VKGILS-NH2 | VKGILS-NH2 is a reversed control peptide for SLIGKV-NH2, which is a protease-activated receptor 2 (PAR2) agonist. Synonyms: retro-PAR-2 (1-6) amide (human); retro-SLIGKVamide; Thrombin Receptor-Like 1 (6-1) amide (human); Proteinase Activated Receptor 2 (6-1) amide (human); PAR-2 (6-1) amide (human). Grade: 98%. CAS No. 942413-05-0. Molecular formula: C28H54N8O7. Mole weight: 614.79. | |
| Voriconazole | Voriconazole is an antifungal medication used to treat a number of fungal infections, including aspergillosis, candidemia, and esophageal candidiasis. Synonyms: UK-109496; UK 109496; UK109496; UK109,496; UK-109,496; UK 109,496; Voriconazole; Vfend. Grade: >98%. CAS No. 137234-62-9. Molecular formula: C16H14F3N5O. Mole weight: 349.31. | |
| VSV-G Peptide | VSV-G Peptide, vesicular stomatitis virus G (VSV-G) protein fragment, is commonly engineered onto the N- or C- terminus of a protein of interest so that the tagged protein can be analyzed and visualized using immunochemical methods. Synonyms: H-Tyr-xiThr-Asp-xiIle-Glu-Met-Asn-Arg-Leu-Gly-Lys-OH; L-tyrosyl-(3xi)-L-threonyl-L-alpha-aspartyl-(3xi)-L-isoleucyl-L-alpha-glutamyl-L-methionyl-L-asparagyl-L-arginyl-L-leucyl-glycyl-L-lysine. Molecular formula: C57H94N16O19S. Mole weight: 1339.52. | |
| WF-3681 | WF-3681 is an aldose reductase inhibitor produced by Chaetomella raphigera Swift No. 3681. Synonyms: WF 3681. CAS No. 105364-56-5. Molecular formula: C13H12O5. Mole weight: 248.23. | |
| WKYMVM | WKYMVm is a selective agonist for the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM) that is expressed on immune cells. WKYMVm induces Ca2+ mobilization and superoxide production in, and chemotaxic migration of, monocytes and neutrophils. Synonyms: Trp-Lys-Tyr-Met-Val-D-Met-NH2; Leukocyte chemoattractant peptide; W-Peptide. CAS No. 187986-17-0. Molecular formula: C41H61N9O7S2. Mole weight: 856.11. | |
| WKYMVM 2TFA | WKYMVM 2TFA is a selective agonist of the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM), and FPR3 (EC50 = 3 nM) and is expressed on immune cells. It induces Ca2+ mobilization and superoxide production, as well as chemotactic migration of monocytes and neutrophils. Synonyms: H-Trp-Lys-Tyr-Met-Val-D-Met-NH2.2TFA; L-tryptophyl-L-lysyl-L-tyrosyl-L-methionyl-L-valyl-D-methioninamide trifluoroacetic acid; (2R,5S,8S,11S,14S,17S)-17-Amino-14-(4-aminobutyl)-11-(4-hydroxybenzyl)-18-(1H-indol-3-yl)-5-isopropyl-2,8-bis[2-(methylsulfanyl)ethyl]-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecan-1-amide trifluoroacetate; W-Peptide TFA salt; WKYMVm TFA salt. Grade: ≥95%. Molecular formula: C41H61N9O7S2.2C2HF3O2. Mole weight: 1084.16. | |
| Wortmannin | It is an antibiotic produced by the strain of Pen. wortmanni 989. It has strong antifungal effect. It is a specific covalent inhibitor of phosphoinositide 3-kinases (PI3Ks) and Polo-Like kinase 1 (PLK1). It is a commonly used cell biology reagent that has been used previously in research to inhibit DNA repair, receptor-mediated endocytosis and cell proliferation. Uses: Immunosuppressive agents. Synonyms: Antibiotic SL-2052; (1alpha,11alpha)-11-(Acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan-3,7,17-trione; (1S,6bR,9aS,11R,11bR)-1-(Methoxymethyl)-9a,11b-dimethyl-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3H-furo[4,3,2-de]indeno[4,5-h]isochromen-11-yl acetate. Grade: 95%. CAS No. 19545-26-7. Molecular formula: C23H24O8. Mole weight: 428.43. | |
| WRW4 | WRW4 is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. WRW4 inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and blocks intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Synonyms: WRW4; WRW 4; WRW-4. CAS No. 878557-55-2. Molecular formula: C61H65N15O6. Mole weight: 1104.28. | |
| WRW4 TFA | WRW4 TFA is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. WRW4 inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and blocks intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Synonyms: H-Trp-Arg-Trp-Trp-Trp-Trp-NH2.TFA; L-tryptophyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-tryptophyl-L-tryptophanamide trifluoroacetic acid; WRW4 Trifluoroacetate; WRW4 (trifluoroacetate salt). Grade: ≥95%. Molecular formula: C63H66F3N15O8. Mole weight: 1218.29. | |
| WSPC Biotin-PEG3-DBCO | WSPC Biotin-PEG3-DBCO is a polyethylene glycol (PEG)-based PROTAC linker. WSPC Biotin-PEG3-DBCO can be used in the synthesis of a series of PROTACs. Molecular formula: C53H68N8O17S2. Mole weight: 1153.28. | |
| X-206 | X-206 is an ionophore antibiotic produced by Streptomyces sp. X 206. It acts as a potent and selective inhibitor of SARS-CoV-2. Synonyms: Antibiotic X-206. CAS No. 36505-48-3. Molecular formula: C47H82O14. Mole weight: 871.1. | |
| Xanthosine 5'-(trihydrogen diphosphate), trisodium salt | Xanthosine 5'-(trihydrogen diphosphate), trisodium salt. CAS No. 84215-50-9. Molecular formula: C10H11N4Na3O12P2. Mole weight: 510.130772. | |
| Xanthothricin | It is a nitrogenous heterocyclic antibiotic produced by the strain of Str. sp. and Pseudomonas cocovenenans. It has anti-bacterial and mycobacterium effects. Synonyms: Toxoflavin; Toxoflavine; Pyrimido(5,4-e)-1,2,4-triazine-5,7-(1H,6H)-dione, 1,6-dimethyl-; 1-methylreumycin; Fervenuline; GNF-PF-67. Grade: >98% by HPLC. CAS No. 84-82-2. Molecular formula: C7H7N5O2. Mole weight: 193.16. | |
| Xenin | Xenin, a 25-amino acid peptide initially isolated from human gastric mucosa, has 6 C-terminal amino acids in common with amphibian xenopsin. Xenin may stimulate the enzyme release from the exocrine pancreas. Synonyms: Xenin-25; L-Methionyl-L-leucyl-L-threonyl-L-lysyl-L-phenylalanyl-L-α-glutamyl-L-threonyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-valyl-L-lysylglycyl-L-leucyl-L-seryl-L-phenylalanyl-L-histidyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine; Human Xenin. CAS No. 144092-28-4. Molecular formula: C139H224N38O32S. Mole weight: 2971.57. | |
| Xenopsin | Xenopsin, the neurotensin-like octapeptide from Xenopusskin at the carboxyl terminus of its precursor, shows sequence homology to mammalian neurotensin and shares a number of its biological properties. Synonyms: H-Pyr-Gly-Lys-Arg-Pro-Trp-Ile-Leu-OH; 5-oxo-L-prolylglycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine. Grade: >98%. CAS No. 51827-01-1. Molecular formula: C47H73N13O10. Mole weight: 980.16. | |
| XJ735 | XJ735, a RGD peptidomimetic αVβ3 integrin antagonist, contains anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. Synonyms: XJ 735; XJ-735; Cyclo[L-alanyl-L-arginylglycyl-L-α-aspartyl-3-(aminomethyl)benzoyl]; 3,6,9,12,15-Pentaazabicyclo[15.3.1]heneicosa-1(21),17,19-triene-5-acetic acid, 11-[3-[(aminoiminomethyl)amino]propyl]-14-methyl-4,7,10,13,16-pentaoxo-, (5S,11S,14S)-. Grade: ≥95%. CAS No. 153381-95-4. Molecular formula: C23H32N8O7. Mole weight: 532.55. | |
| X-press Tag Peptide | X-press Tag Peptide, an N-terminal leader peptide containing a polyhistidine sequence, is a tag peptide used for protein purification. Synonyms: H-Asp-Leu-Tyr-Asp-Asp-Asp-Asp-Lys-OH; L-alpha-aspartyl-L-leucyl-L-tyrosyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-lysine. Molecular formula: C41H59N9O20. Mole weight: 997.96. | |
| (Z)-4-Hydroxy Tamoxifen-[d5] | One of the labelled impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: (Z) 4-Hydroxy Tamoxifen Ethyl-d5. Grade: > 95%. CAS No. 164365-20-2. Molecular formula: C26H24D5NO2. Mole weight: 392.53. | |
| Z-AEVD-FMK | Z-AEVD-FMK is a cell-permeant and irreversible caspase-10 inhibitor. It is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Synonyms: Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone; (5S,8S,11S,14S)-Methyl 14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,1 3-tetraazahexadecan-16-oate; Z-A-E(OMe)-V-Asp(OMe)-FMK; Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK. Grade: ≥95%. CAS No. 1135688-47-9. Molecular formula: C28H39FN4O10. Mole weight: 610.63. | |
| Zalcitabine Triphosphate Trisodium Salt | Zalcitabine Triphosphate Trisodium Salt has the free acid form of Zalcitabine Triphosphate. And it can serve as an inhibitor of viral RNA synthesis. As well as a metabolite of Zalcitabine. Synonyms: 2',3'-Dideoxycytidine-5'-triphosphate Trisodium Salt. Grade: 95%. Molecular formula: C9H13N3Na3O12P3. Mole weight: 517.1. | |
| Z-Asp-CH2-DCB | Z-Asp-CH2-DCB is a broad caspase inhibitor that blocks apoptosis by non-selectively inhibiting caspase activity. At 1-100 μM, it can dose-dependently block the production of IL-1β, TNF-α, IL-6, and IFN-γ by human peripheral blood mononuclear cells as well as inhibit T cell proliferation. Synonyms: ICE Inhibitor V; Z-Asp-[(2,6-dichlorobenzoyl)oxy]methane; Caspase-1 Inhibitor V; (3S)-5-(2,6-Dichlorobenzoyl)oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid. Grade: ≥98%. CAS No. 153088-73-4. Molecular formula: C20H17Cl2NO7. Mole weight: 454.3. | |
| Z-ASTD-FMK | Z-ASTD-FMK is a cell-permeant and irreversible inhibitor of endothelial monocyte-activated polypeptide II (EMAP II). Synonyms: EMAP II inhibitor; Z-Ala-Ser-Thr-Asp(OMe)-Fluoromethylketone; Z-ASTD(OMe)-fmk; Cbz-Ala-Ser-Thr-Asp(OMe)-CH2F. Grade: ≥95%. Molecular formula: C24H33FN4O10. Mole weight: 556.54. | |
| Z-ATAD-FMK | Z-ATAD-FMK is a cell-permeant caspase-12 inhibitor. It was shown to suppress annular cell apoptosis in vitro. Synonyms: Caspase-12 Inhibitor; Z-ATAD-FMK; Z-ATAD-fluoromethylketone. Grade: ≥95%. Molecular formula: C24H33FN4O9. Mole weight: 540.54. | |
| Z-DEVD-FMK | Z-DEVD-FMK is a cell-permeant, irreversible caspase-3 inhibitor that can be used as an anaesthetic agent. It has been shown to suppress tumor cell apoptosis. Uses: Cysteine proteinase inhibitors. Synonyms: Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK; Caspase-3 Inhibitor; Z-D(OMe)E(Ome)VD(OMe)-FMK; benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone; Caspase-3 Inhibitor II; Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone; Z-DEVD-fluoromethylketone. Grade: ≥95%. CAS No. 210344-95-9. Molecular formula: C30H41FN4O12. Mole weight: 668.67. | |
| Z-DQMD-FMK | Z-DQMD-FMK has been found to be a Caspase-3 inhibitor and could induce small cell lung cancer cell death in vitro. Synonyms: Z-D(OMe)QMD(OMe)-fmk; benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone; Z-Asp(OMe)-Gln-Met-Asp(OMe) fluoromethyl ketone; L-Methioninamide, N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-glutaminyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester; methyl (5S,8S,11S,14S)-8-(3-amino-3-oxopropyl)-14-(2-fluoroacetyl)-5-(2-methoxy-2-oxoethyl)-11-(2-(methylthio)ethyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate. Grade: ≥95%. CAS No. 767287-99-0. Molecular formula: C29H40FN5O11S. Mole weight: 685.72. | |
| Zelkovamycin | It is a cyclic peptide antibiotic produced by the strain of Streptomyces sp. K96-0670. It has anti-Xanthomonas oryzae, Acholeplasma laidlawii, Piricularia oryzae and Staphylococcus aureus activity, but no effect on other bacteria and fungi. Synonyms: Cyclo[2-aminobutanoyl-(2Z)-2-amino-2-butenoyl-N-methylglycyl-2-(1-aminoethyl)-4-thiazolecarbonyl-7-methoxytryptophyl-3-oxoisovalylglycyl]; Zelcovamycin. Grade: ≥95%. CAS No. 221197-33-7. Molecular formula: C36H45N9O9S. Mole weight: 779.86. | |
| Z-FF-FMK | Z-FF-FMK is a cell-permeant and irreversible inhibitor of cathepsin B and cathepsin L. Synonyms: Cathepsin L Inhibitor I; Z-Phe-Phe-CH2F; Z-Phe-Phe-fluoromethyl ketone. Grade: ≥95%. CAS No. 105608-85-3. Molecular formula: C27H27FN2O4. Mole weight: 462.52. | |
| Z-Gly-gly-phe-chloromethylketone | Z-Gly-gly-phe-chloromethylketone is a site-specific inhibitor of chymotrypsin. Synonyms: N-[(Benzyloxy)carbonyl]glycyl-N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]glycinamide. CAS No. 35172-59-9. Molecular formula: C22H24ClN3O5. Mole weight: 445.9. | |
| Z-IETD-FMK | Z-IETD-FMK is a selective and cell permeable caspase 8 inhibitor. Z-IETD-FMK inhibits T cell proliferation induced by PHA or anti-CD3 plus anti-CD28 without toxicity of resting T cells. Synonyms: caspase-8 inhibitor; Z-IE(OMe)TD(OMe)-FMK; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F; Z-Ile-Glu(OMe)-Thr-Asp(OMe) fluoromethylketone; N-benzyloxycarbonyl-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethylketone; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone. Grade: ≥95%. CAS No. 210344-98-2. Molecular formula: C30H43FN4O11. Mole weight: 654.69. | |
| Z-Ile-Glu(O-t-butyl)-Ala-Leucinal | PSI is a drug that blocks the action of proteasomes, protein complexes that degrade unneeded and damaged proteins. It causes dopaminergic cell death in vitro and prevents activation of NF-κB in response to TNF-α and okadaic acid by inhibiting IκB-α degradation. Uses: Cysteine proteinase inhibitors. Synonyms: Proteasome Inhibitor I; PSI peptide; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-alpha-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester. Grade: ≥ 90 % by HPLC. CAS No. 158442-41-2. Molecular formula: C32H50N4O8. Mole weight: 618.76. | |
| Z-Ile-Leu-aldehyde | Z-Ile-Leu-aldehyde ia a cell-permeable and reversible inhibitor that inhibits γ-secretase and Notch signaling. It induces apoptosis of murine MOPC315.BM myeloma cells with high Notch activity in vitro. It has potent anti-MM activity and reduces osteolytic lesions in vivo. Uses: Gamma secretase inhibitors and modulators. Synonyms: Z-IL-CHO; GSI-XII; Z-Ile-Leu-al; Z Ile Leu al; Z IL CHO; Gamma-secretase inhibitor XII; [(1S,2S)-1-((S)-1-Formyl-3-methyl-butylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester; Benzyl ((2S,3S)-3-methyl-1-(((S)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate; N-benzyloxycarbonyl-L-isoleucyl-L-leucinal. Grade: ≥95%. CAS No. 161710-10-7. Molecular formula: C20H30N2O4. Mole weight: 362.46. | |
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