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(±)10(11)-EDP Ethanolamide
(±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist. Synonyms: 10,11-EDP-EA; 10,11-EDP epoxide; 10,11-epoxy Docosapentaenoic Ethanolamide. Grade: ≥98%. CAS No. 2123484-71-7. Molecular formula: C24H37NO3. Mole weight: 387.56.
(10α,8β)-Dihydroxy Naltrexone
(10α, 8β)-Dihydroxy Naltrexone is a derivative of Naltrexone, which is used to treat alcohol dependence and prevent relapse of opioid dependence. Molecular formula: C20H23NO6. Mole weight: 373.40.
(10β,8β)-Dihydroxy Naltrexone
(10β,8β)-Dihydroxy Naltrexone is a derivative of Naltrexone, which is used to treat alcohol dependence and prevent relapse of opioid dependence. Molecular formula: C20H23NO6. Mole weight: 373.40.
(±)-10-Hydroxycamptothecin
(±)-10-Hydroxycamptothecin is an alkaloid derived from the seed or root bark of the deciduous plant Camptotheca acuminata. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones. It exhibits anticancer and antiangiogenic activities. It can be used in cosmetics material. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (±)-; (+/-)-10-Hydroxycamptothecin; 4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. Grade: ≥95%. CAS No. 64439-81-2. Molecular formula: C20H16N2O5. Mole weight: 364.35.
(10R,12S) Caspofungin
(10R,12S) Caspofungin is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H88N10O15. Mole weight: 1093.31.
(±)11(12)-EET
11, 12-Epoxyeicosatrienoic acid is an epoxyeicosatrienoic acid (EET). Induction of CYP2C8 in native coronary artery endothelial cells by beta-naphthoflavone enhances the formation of 11, 12-epoxyeicosatrienoic acid, as well as endothelium-derived hyperpolarizing factor-mediated hyperpolarization and relaxatioocoagulation. It also has anti-inflammatory, angiogenic, and cardioprotective properties. Uses: Vasodilator agents. Synonyms: 11,12-Oxido-5,8,14-eicosatrienoic acid; 11,12-epoxy-5,8,14-eicosatrienoic acid; 5,8-Decadienoic acid, 10-(3-(2-octenyl)oxiranyl)-. Grade: ≥95%. CAS No. 123931-40-8. Molecular formula: C20H32O3. Mole weight: 320.5.
(±)11(12)-EET methyl ester
(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. Synonyms: (5Z,8Z,14Z)-11,12-Epoxy-5,8,14-icosatrienoic acid methyl ester; Methyl (5Z,8Z)-10-[3-[(Z)-oct-2-enyl]oxiran-2-yl]deca-5,8-dienoate. Grade: ≥98%. CAS No. 73799-06-1. Molecular formula: C21H34O3. Mole weight: 334.5.
(±)-1-(1,2-Diphenylethyl)piperidine maleate
The meleate salt form of (±)-1-(1,2-Diphenylethyl)piperidine, which has been found to be a high affinity antagonist at the ion channel on the NMDA receptor. Synonyms: (+/-)-1-(1,2-Diphenylethyl)piperidine maleate. Grade: ≥98% by HPLC. CAS No. 207461-99-2. Molecular formula: C19H23N.C4H4O4. Mole weight: 381.47.
(11β)-11,17a-Dihydroxy-17a-[(phosphonooxy)methyl]-D-homoandrosta-1,4-diene-3,17-dione Ammonium Salt
(11β)-11,17a-Dihydroxy-17a-[(phosphonooxy)methyl]-D-homoandrosta-1,4-diene-3,17-dione Ammonium Salt is a derivative of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Grade: 90%. Molecular formula: C21H29O8P.xNH3. Mole weight: 440.42 (free base).
(11β,16α)-11,16-Dihydroxyandrosta-1,4-diene-3,17-dione is a highly potent pharmaceutical compound exhibiting its efficacy in the research of diverse hormone-responsive malignancies. By suppressing the enzymatic activity of aromatase, this remarkable substance successfully diminishes estrogen synthesis, thereby impeding the progression of estrogen-reliant tumors. Its wide-ranging applications in studying breast cancer, endometriosis and prostate cancer render it an indispensable agent in the biomedical sector, facilitating the advancement of tailored interventions against hormonally mediated afflictions. Synonyms: Androsta-1,4-diene-3,17-dione, 11,16-dihydroxy-, (11β,16α)-; (8S,9S,10R,11S,13S,14S,16R)-11,16-dihydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione; 1,4-Androstadien-11-beta-16-alpha-Diol-3,17-Dione. Grade: ≥95%. CAS No. 910299-74-0. Molecular formula: C19H24O4. Mole weight: 316.39.
(11β,16α)-11-Hydroxy-16-(1-oxobutoxy)-androsta-1,4-diene-3,17-dione, commonly known as a synthetic glucocorticoid exhibiting high potency within the biomedical industry. Its multifaceted role encompasses the research of a multitude of inflammatory and autoimmune afflictions, including asthma , arthritis and allergies. Synonyms: Androsta-1,4-diene-3,17-dione, 11-hydroxy-16-(1-oxobutoxy)-, (11β,16α)-; (8S,9S,10R,11S,13S,14S,16R)-11-hydroxy-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-16-yl butyrate; (11β,16α)-11-Hydroxy-3,17-dioxoandrosta-1,4-dien-16-yl butyrate; Butanoic acid, (11β,16α)-11-hydroxy-3,17-dioxoandrosta-1,4-dien-16-yl ester. Grade: >95%. CAS No. 85234-64-6. Molecular formula: C23H30O5. Mole weight: 386.48.
(11β,16α)-11-Hydroxy-16-methyl-17,21-bis(1-oxoacetoxy)-pregna-1,4-diene-3,20-dione is an impurity of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: [2-[(8S,9S,10R,11S,13S,14S,16R,17R)-17-acetyloxy-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate. Molecular formula: C26H34O7. Mole weight: 458.54.
(11β,16α)-21-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-11,16,17-trihydroxy-pregna-1,4-diene-3,20-dione is a derivative of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: Pregna-1,4-diene-3,20-dione, 21-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-11,16,17-trihydroxy-, (11β,16α)-; (11β,16α)-21-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-11,16,17-trihydroxypregna-1,4-diene-3,20-dione. CAS No. 1221150-20-4. Molecular formula: C27H42O6Si. Mole weight: 490.70.
(11β,17Z)-11-Hydroxy-3-oxo-pregna-1,4,17(20)-trien-21-al 20-O-Phosphate Disodium Salt
(11β,17Z)-11-Hydroxy-3-oxo-pregna-1,4,17(20)-trien-21-al 20-O-Phosphate Disodium Salt is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: Prednisolone Impurity. Molecular formula: C21H25Na2O7P. Mole weight: 466.37.
(11β,17Z)-20-(Acetyloxy)-11-hydroxy-3-oxopregna-1,4,17(20)-trien-21-al, is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: (11?,17Z)-20-(Acetyloxy)-11-hydroxy-3-oxopregna-1,4,17(20)-trien-21-al; 118866-09-4. CAS No. 118866-09-4. Molecular formula: C23H28O5. Mole weight: 384.46.
(11β)-9-Fluoro-11-hydroxy-16-methyl-3-oxo-androsta-1,4,16-triene-17-carboxylic Acid is one of Clobetasol propionate impurities. Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened hedgehog pathway receptor agonist. It can be used as an anti-inflammatory, immunosuppressive and antimitotic agent. Active in vivo. CAS No. 59861-00-6. Molecular formula: C21H25FO4. Mole weight: 360.42.
An intermediate of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus. Synonyms: (11β,16β)-11-hydroxy-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; (11β,16β)-11β-hydroxy-2'-methyl-5βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 11β-hydroxy-2'-methyl-5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione. Grade: > 95%. CAS No. 13649-88-2. Molecular formula: C23H29NO4. Mole weight: 383.48.
(11bR)-3-Isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2,9-diol is a derivative of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: 2H-Benzo[a]quinolizine-2,9-diol, 1,3,4,6,7,11b-hexahydro-10-methoxy-3-(2-methylpropyl)-, (11bR)-; (±)-9-deMe-DTBZ; (11bR)-1,3,4,6,7,11b-Hexahydro-10-methoxy-3-(2-methylpropyl)-2H-Benzo[a]quinolizine-2,9-diol. CAS No. 1795790-34-9. Molecular formula: C18H27NO3. Mole weight: 305.41.
11-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one stands as a noteworthy pharmacological entity, aiding in the research of drug development, targeting specific afflictions unveiling a research of possibilities. Synonyms: trans-(+/-)-11-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one; rel-(3aR,12bR)-11-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one; ASM-6 Isomer; trans-11-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one; (3aS,12bS)-11-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one. Grade: 95%. CAS No. 129385-59-7. Molecular formula: C17H14ClNO2. Mole weight: 299.75.
11-Chloro-2,3-dihydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one is a remarkable pharmaceutical entity, showcasing profound efficacy in studying a multitude of afflictions, encompassing cancer, inflammation and neurodegenerative disorders. Synonyms: 11-Chloro-2-methyl-2,3-dihydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one; 1H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one, 11-chloro-2,3-dihydro-2-methyl-. Grade: 95%. CAS No. 1012884-46-6. Molecular formula: C17H12ClNO2. Mole weight: 297.74.
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose
It is an intermediate in the preparation of Cepecitabine. Synonyms: 5-Deoxy-1,2,3-triacetyl-5-deoxy-β-D-ribose; 5-Deoxy-β-D-ribofuranose Triacetate; (2S,3R,4R,5R)-5-methyltetrahydrofuran-2,3,4-triyl triacetate; b-D-Ribofuranose, 5-deoxy-, triacetate; 1-O,2-O,3-O-Triacetyl-5-deoxy-beta-D-ribofuranose; 1,2,3-Triacetyl-5-deoxy-D-ribose. Grade: ≥98% by GC. CAS No. 62211-93-2. Molecular formula: C11H16O7. Mole weight: 260.24.
(1,2,6,7,-Tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Ramelteon. Synonyms: 2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile; Dihydro-1H-indeno[5,4-B]furan-8(2H)-ylidene)acetonitrile. Grade: >95%. CAS No. 221530-44-5. Molecular formula: C13H11NO. Mole weight: 197.23.
1,2-Benzisothiazolin-3-one
1,2-Benzisothiazol-3(2H)-one is an antimicrobial agent. Synonyms: 1,2-Benzisothiazolin-3-one; benzisothiazolone. Grade: 98.0%. CAS No. 2634-33-5. Molecular formula: C7H5NOS. Mole weight: 151.19.
1,3,9-Trimethyluric acid
1,3,9-Trimethyluric acid is an alkaloid isolated from the marine sponge Amphimedon viridis. Synonyms: 7,9-Dihydro-1,3,9-trimethyl-1H-purine-2,6,8(3H)-trione; NSC 400135; 1,3,9-Trimethyl-1H-purine-2,6,8(3H,7H,9H)-trione; 1,3,9-trimethyl-7,9-dihydro-3H-purine-2,6,8-trione; 1,3,9-Trimethyl-harnsaeure; 1,3,9-trimethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione; 8-Oxocaffeine. Grade: 98%. CAS No. 7464-93-9. Molecular formula: C8H10N4O3. Mole weight: 210.19.
(13S,14R, 17R)-Ethinyl Estradiol
A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (13S,14R,17R)-17-Ethynyl-13-methyl-12,13,14,15,16,17-hexahydro-11H-cyclopenta[a]phenanthrene-3,17-diol; 17β-Dihydro-17α-ethynyl-14β-equillenin. Grade: > 95%. Molecular formula: C20H20O2. Mole weight: 292.38.
(13S,14R, 17S)-Ethinyl Estradiol
A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (13S,14R,17S)-17-ethynyl-13-methyl-12,13,14,15,16,17-hexahydro-11H-cyclopenta[a]phenanthrene-3,17-diol. Grade: > 95%. Molecular formula: C20H20O2. Mole weight: 292.38.
(13S,14S, 17R)-Ethinyl Estradiol
A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (13S,14R,17R)-17-Ethynyl-13-methyl-12,13,14,15,16,17-hexahydro-11H-cyclopenta[a]phenanthrene-3,17-diol. Grade: > 95%. Molecular formula: C20H20O2. Mole weight: 292.38.
(13S,14S, 17S)-Ethinyl Estradiol
A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (13S,14S,17S)-17-Ethynyl-13-methyl-12,13,14,15,16,17-hexahydro-11H-cyclopenta[a]phenanthrene-3,17-diol. Grade: > 95%. Molecular formula: C20H20O2. Mole weight: 292.38.
An impurity of Gestodene, which is a synthetic progesterone used primarily in female contraceptives and menopausal hormone therapy. Synonyms: (13S)-17-Acetyl-13-ethyl-6,7,8,9,10,11,12,13-octahydro-1H-cyclopenta[a]phenanthren-3(2H)-one; Gestodene Related Compound 10; 13-Ethyl-18,19-dinorpregna-4,14,16-triene-3,20-dione; (8R,9R,10R,13S)-17-Acetyl-13-ethyl-1,2,6,7,8,9,10,11,12,13-decahydro-3H-cyclopenta[a]phenanthren-3-one. Grade: ≥95%. CAS No. 932388-88-0. Molecular formula: C21H26O2. Mole weight: 310.43.
(+)-(14beta)-Dihydrovinpocetine
An impurity of Vinpocetine. Vinpocetine, isolated from the lesser periwinkle plant, is a derivative of the vinca alkaloid vincamine with an effect of cerebral blood-flow enhancing and neuroprotection. Vinpocetine was approved for the treatment of cerebrovascular disorders and age-related memory impairment in Eastern Europe. Synonyms: (12S,13aS,13bS)-13a-Ethyl-2,3,5,6,12,13,13a,13b-octahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic Acid Ethyl Ester; (3α,14β,16α)-14,15-Dihydro-eburnamenine-14-carboxylic Acid Ethyl Ester; Ethyl (14β)-14,15-dihydroapovincaminate. CAS No. 57517-54-1. Molecular formula: C22H28N2O2. Mole weight: 352.47.
1,4-Dihydro-1-methyl-4-oxonicotinamide
A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Synonyms: 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide. Grade: > 95%. CAS No. 769-49-3. Molecular formula: C7H8N2O2. Mole weight: 152.15.
(+)-1,4-Di-O-benzyl-D-threitol
(+)-1,4-Di-O-benzyl-D-threitol, a highly prized compound within the biomedical industry, constitutes a vital component for the creation of groundbreaking pharmaceuticals. Unveiling its indispensability, this compound triumphs as an integral player in combating various ailments such as cancer and diabetes. Prudently procured from reputed suppliers, it guarantees unparalleled purity and efficacy. Synonyms: (+)-(2R,3R)-1,4-Bis(benzyloxy)-2,3-butanediol. CAS No. 91604-41-0. Molecular formula: C18H22O4. Mole weight: 302.36.
(-)-1,4-Di-O-benzyl-L-threitol
(-)-1,4-Di-O-benzyl-L-threitol is a chiral building block involved in the synthesis of antiviral drugs, specifically for treating HIV. It's also applied in the preparation of other therapeutically significant compounds in the biomedical industry. Synonyms: (-)-(2S,3S)-1,4-Bis(benzyloxy)-2,3-butanediol. CAS No. 17401-06-8. Molecular formula: C18H22O4. Mole weight: 302.36.
1-(4-Fluorobenzyl)-2-chlorobenzimidazole
2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor. Synonyms: 1-(4-Fluorobenzyl)-2-chlorobenzimidazole. Grade: 98 %. CAS No. 84946-20-3. Molecular formula: C14H10ClFN2. Mole weight: 260.69.
(14R)-14-Hydroxy Clarithromycin
(14R)-14-Hydroxy Clarithromycin is a derivative of clarithromycin. Synonyms: (14R)-14-hydroxy-6-O-methylerythromycine A; 14-(R) Hydroxyclarithromycin. CAS No. 116836-41-0. Molecular formula: C38H69NO14. Mole weight: 763.96.
(14R)-paricalcitol
(14R)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Molecular formula: C27H44O3. Mole weight: 416.64.
1,5-Anhydro-D-glucitol
1,5-Anhydro-D-glucitol (ADG) is a biomarker primarily used in the research of diabetes. It has the potential to be developed for early detection of diabetes and diabetes mellitus. Synonyms: 1,5-Anhydro-D-sorbitol; 1,5-Anhydroglucitol. Grade: 98.0%. CAS No. 154-58-5. Molecular formula: C6H12O5. Mole weight: 164.16.
(-)-15-Deoxyspergualin
(-)-15-Deoxyspergualin is an antineoplastic agent. Uses: Immunosuppressive agents. Synonyms: Deoxyspergualin; (-)-Gusperimus. CAS No. 89149-10-0. Molecular formula: C17H37N7O3. Mole weight: 387.5.
(-)-15-Deoxyspergualin trihydrochloride
(-)-15-Deoxyspergualin trihydrochloride is an antineoplastic agent. Synonyms: Gusperimus (-)-form trihydrochloride; (-)-Gusperimus trihydrochloride. Grade: 95%. CAS No. 84937-45-1. Molecular formula: C17H40Cl3N7O3. Mole weight: 496.904.
(+)-15-epi Cloprostenol
Cloprostenol is a synthetic prostaglandin F2α (PGF2α) analog and a potent FP receptor agonist. Synonyms: D-Cloprostenol; (+)-15(S)-Cloprostenol; 15S-Cloprostenol; 15-Epicloprostenol. Grade: ≥98%. CAS No. 54276-22-1. Molecular formula: C22H29ClO6. Mole weight: 424.9.
1,6-Anhydro-β-D-glucose
1,6-Anhydro-β-D-glucose is a primary component of Pyrococcus furiosus bacterial cellulose, relevant in studying enzymatic degradation. It aids in studying and developing treatments for diabetes and carbohydrate metabolic disorders. Synonyms: 1,6-Anhydro-b-D-glucopyranose. Grade: 98.0%. CAS No. 498-07-7. Molecular formula: C6H10O5. Mole weight: 162.14.
16-Dehydropregnenolone acetate
16-Dehydropregnenolone acetate is an impurity of Abiraterone, which is a CYP17A1 inhibitor and by extension androgen synthesis inhibitor. In combination with prednisone, it is indicated for the treatment of patients with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel under the trade name Zytiga. Synonyms: Dehydropregnenolone acetate; 16,17-Didehydropregnenolone acetate. Grade: > 95%. CAS No. 979-02-2. Molecular formula: C23H32O3. Mole weight: 356.51.
(±)16-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Synonyms: 5,8,11,14-Eicosatetraenoicacid, 16-hydroxy-, (5Z,8Z,11Z,14Z)-. Grade: ≥98%. CAS No. 128914-46-5. Molecular formula: C20H32O3. Mole weight: 320.5.
(1-6)-Icatibant
(1-6)-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: D-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanine; D-Arg-Arg-Pro-Hyp-Gly-Thi-OH. CAS No. 2698340-93-9. Molecular formula: C31H50N12O8S. Mole weight: 750.88.
(±)17(18)-EpETE
The epoxygenase pathway is one of the three major branches of eicosanoid biosynthesis. Synonyms: (±)17,18-EEQ; (±)17,18-epoxy Eicosatetraenoic Acid; (5Z,8Z,11Z,14Z)-16-(3-ethyloxiran-2-yl)hexadeca-5,8,11,14-tetraenoic acid. Grade: ≥90%. Molecular formula: C20H30O3. Mole weight: 318.5.
(±)17(18)-EpETE-Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. It is formed from the endocannabinoid eicosapentaenoic ethanolamide (EPEA) via cytochrome P450 (CYP) epoxygenases and hydrolyzed by soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH). Synonyms: 17,18-EEQ-EA; (±)17,18-EEQ-Ethanolamide; (±)17(18)-EpETE-EA; 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide. Grade: ≥98%. CAS No. 2123491-23-4. Molecular formula: C22H35NO3. Mole weight: 361.5.
An impurities of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Grade: > 95%. Molecular formula: C24H34O4. Mole weight: 386.54.
An impurities of Progesterone.Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Progesterone is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. Grade: > 95%. Molecular formula: C22H32O3. Mole weight: 344.5.
(17α)-17-Hydroxy-19-norpregn-5-en-20-yn-3-one Cyclic 1,2-Ethanediyl Acetal is an impurity of Norethindrone, which is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases. Synonyms: Spiro[3H-cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane] 19-Norpregn-5-en-20-yn-3-one deriv.; Spiro[3H-cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-ol, 17-ethynyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-13-methyl-, (8R,9S,10R,13S,14S,17R)-. CAS No. 22170-58-7. Molecular formula: C22H30O3. Mole weight: 342.47.
(17α)-19-Norpregn-5-en-20-yne-3,17-diol
(17α)-19-Norpregn-5-en-20-yne-3,17-diol is an intermediate in the preparation of Norethindrone, which is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases. Synonyms: Norethindrone Impurity 36; (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol; Estr-5-ene-3,17-diol, 17-ethynyl-, (17β)-. Grade: ≥95%. CAS No. 1492-41-7. Molecular formula: C20H28O2. Mole weight: 300.43.
(+/-)-17α-Dutasteride
An impurity of Dutasteride, which is a potent dual inhibitor of 5α-reductase isoenzymes type 1 and type 2. Synonyms: Dutasteride Impurity E (rel-isomer); Dutasteride EP Impurity E (rel-isomer); 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7R,9aS,9bS,11aR)-rel-; rel-(4aR,4bS,6aS,7R,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; (+/-)-17a-Dutasteride; rac-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5a-androst-1-ene-17a-carboxamide. Grade: ≥95%. CAS No. 1796930-46-5. Molecular formula: C27H30F6N2O2. Mole weight: 528.53.
(17β)-3,17-Bis-O-[(tetrahydro-2H-pyran-2-yl)-6-O-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfenyl]nonyl-estra-1,3,5(10),6(7)-tetraene is an impurity of Fulvestrant, which is a selective estrogen receptor degrader (SERD) used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women. Molecular formula: C42H61F5O5S. Mole weight: 772.99.
(17β)-Estra-1,3,5(10),6,8-pentaene-3,17β-diol Diacetate is an intermediate in the synthesis of Equilenin, which is an estrogenic steroid hormone obtained from the urine of pregnant mares. Synonyms: 3,17beta-Diacetoxyestra-1,3,5,7,9-pentene; (13S,14S,17S)-13-methyl-12,13,14,15,16,17-hexahydro-11H-cyclopenta[a]phenanthrene-3,17-diyl diacetate; Estra-1,3,5(10),6,8-pentaene-3,17β-diol Diacetate. CAS No. 1423-96-7. Molecular formula: C22H24O4. Mole weight: 352.42.
(17β)-Spiro[androsta-1,4-diene-17,2'-oxiran]-3-one is an impurity of Spironolactone, which is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Synonyms: Spiro[androsta-1,4-diene-17,2'-oxiran]-3-one, (17β)-; (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-oxiran]-3(6H)-one. Grade: ≥95%. CAS No. 55706-91-7. Molecular formula: C20H26O2. Mole weight: 298.43.
17-GMB-APA-GA
17-GMB-APA-GA, an ADC cytotoxin, is a potent HSP90 inhibitor used to study latent T. gondii infection. Synonyms: Geldanamycin, 17-demethoxy-17-[[3-[[4-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxobutyl]amino]propyl]amino]-; (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-[(3-{[4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoyl]amino}propyl)amino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate. Grade: >99.3%. CAS No. 256337-10-7. Molecular formula: C39H53N5O11. Mole weight: 767.87.
(±)17-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. Synonyms: 17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; (5Z,8Z,11Z,14Z)-17-hydroxyicosa-5,8,11,14-tetraenoic Acid; 17-hydroxyeicosa-all-cis-5,8,11,14-tetraenoic acid. Grade: ≥98%. CAS No. 128914-47-6. Molecular formula: C20H32O3. Mole weight: 320.5.
6-Deschloro Cyproterone Acetate is an impurity of Cyproterone acetate. Synonyms: 6-Deschloro Cyproterone Acetate; (1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione; 17-Hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione Acetate. Grade: > 95%. CAS No. 2701-50-0. Molecular formula: C24H30O4. Mole weight: 382.5.
18 β-Glycyrrhetintic Acid
Enoxolone is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It exhibits antiallergic, antibacterial, and antiviral properties and is commonly used for allergic or infectious skin inflammation. Enoxolone is a natural compound used in cosmetics material. Uses: The treatment of allergic or infectious skin inflammation. Synonyms: Enoxolone; Glycyrrhetinic acid; Uralenic acid; Glycyrrhetic acid; Rhetinic Acid; 18-beta-Glycyrrhetinic acid; BRN 2229654; NSC 35347. Grade: >98%. CAS No. 471-53-4. Molecular formula: C30H46O4. Mole weight: 470.68.
(±)-18-Methoxycoronaridine
18-Methoxycoronaridine is a derivative of ibogaine. It is a α3β4 nicotinic antagonist and, in contrast to ibogaine, has no affinity at the α4β2 subtype nor at NMDA-channels nor at the serotonin transporter, and has significantly reduced affinity for sodium channels and for the σ receptor, but retains modest affinity for μ-opioid receptors where it acts as an antagonist of κ-opioid receptors. Synonyms: 18-Methoxycoronaridine; (+/-)-18-Methoxycoronaridine. CAS No. 188125-42-0. Molecular formula: C22H28N2O3. Mole weight: 368.5.
(±)19(20)-EDP Ethanolamide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). Synonyms: 19,20-DHEA epoxide; 19,20-epoxy docosapentaenoic acid ethanolamide; 19,20-EDP-EA; 19,20-EDP epoxide. Grade: ≥98%. CAS No. 2123485-34-5. Molecular formula: C24H37NO3. Mole weight: 387.55.
1-Actamido-3,5-dimethyladmantane
N-Acetyl Memantine is an intermediate used for preparation of Memantine. Synonyms: N-Acetyl Memantine; N-(3,5-Dimethyltricyclo[3.3.1.13,7]dec-1-yl)acetamide; N-(3,5-Dimethyl-1-adamantyl)acetamide; 1-Acetamido-3,5-dimethyladamantane. Grade: > 95%. CAS No. 19982-07-1. Molecular formula: C14H23NO. Mole weight: 221.34.
(1aR,2R,2aR,5aS,6S,6aS)-Tetrahydro-1aH-2,6-methanooxireno[2,3-f]isoindole-3,5(4H,5aH)-dione is a potent and highly selective inhibitor, finding extensive application in the research of a diverse range of diseases. Employing a mechanism of action that exclusively targets specific disease-related pathways, this exceptional product showcases its effectiveness through the inhibition of cancer cell proliferation and tumor volume reduction. Synonyms: (1R,2R,6S,7S,8S,10R)-9-Oxa-4-azatetracyclo[5.3.1.02,6.08,10]undecane-3,5-dione; 2,6-Methano-2H-oxireno[f]isoindole-3,5(1aH,4H)-dione, tetrahydro-, (1aR,2R,2aR,5aS,6S,6aS)-; 2,6-Methano-2H-oxireno[f]isoindole-3,5(1aH,4H)-dione, tetrahydro-, (1aα,2β,2aβ,5aβ,6β,6aα)-. Grade: >95%. CAS No. 114030-19-2. Molecular formula: C9H9NO3. Mole weight: 179.17.
(1aR,2R,2aS,5aR,6S,6aS)-Hexahydro-3H-2,6-methanooxireno[2,3-f]isoindole-3,5(4H)-dione is a groundbreaking compound hailing from the biomedical industry unveiling its potential as a revolutionary force in drug development in ailments including cancer, neurodegenerative disorders and autoimmune conditions. Grade: >95%. Molecular formula: C9H9NO3. Mole weight: 179.18.
(1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid is a biomedical compound, exhibiting exceptional potential in studying the diverse landscape of cancer types through its profound anti-tumor efficacy. Synonyms: 8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid, 5-(1,1-dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-, (1aR,5S,8S,10R,22aR)-; (1R,18R,20R,24S,27S)-7-Methoxy-24-(2-methyl-2-propanyl)-22,25-dioxo-2,21-dioxa-4,11,23,26-tetraazapentacyclo[24.2.1.03,12.05,10.018,20]nonacosa-3,5,7,9,11-pentaene-27-carboxylic acid; (1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid. Grade: 98%. CAS No. 1206524-85-7. Molecular formula: C29H38N4O7. Mole weight: 554.64.
1-Benzhydrylpiperazine
1-Benzhydrylpiperazine is the Cinnarizine impurity. Synonyms: 1-Benzhydrylpiperazine; 1-(Diphenylmethyl)piperazine; 4-(Diphenylmethyl)piperazine; 4-Benzhydrylpiperazine; Benzhydrylpiperazine; N-(Diphenylmethyl)piperazine; N-Benzhydrylpiperazine; NSC 35536; Norcyclizine. Grade: > 95%. CAS No. 841-77-0. Molecular formula: C17H20N2. Mole weight: 252.35.
An impurity of Demiditraz, which is an acaricide agent. CAS No. 944267-48-5. Molecular formula: C19H18N2O. Mole weight: 290.36.
1-Benzyl-1H-indazol-3-ol
Benzydamine Hydrochloride Impurity C is benzydamine intermediate. Synonyms: 1-Benzyl-3-hydroxy-1H-indazole; 1-Benzyl-3-hydroxyindazole; 1,2-Dihydro-1-(phenylmethyl)-3H-indazol-3-one; 1-Benzyl-1,2-dihydro-3H-indazol-3-one; NSC 247064. Grade: > 95%. CAS No. 2215-63-6. Molecular formula: C14H12N2O. Mole weight: 224.26.
1-Benzylimidazole
Benzylimidazole is an inducer of various cytochrome P-450 isozymes and inhibitor of thromboxane A2 synthase. A potential aromatase inhibitor. Uses: Benzylimidazole is an inducer of various cytochrome p-450 isozymes and inhibitor of thromboxane a2 synthase. a potential aromatase inhibitor. Synonyms: 1-(phenylmethyl)imidazole; 1-benzylimidazole. Grade: ≥ 99 %. CAS No. 4238-71-5. Molecular formula: C10H10N2. Mole weight: 158.20.