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3-Desmethylthiocolchicine-3-O-D-glucuronide
3-Desmethylthiocolchicine-3-O-D-glucuronide, an intriguing and efficacious biomedicine, has garnered considerable attention due to its multifaceted therapeutic implications. Originating as an active metabolite of colchicine, a renowned remedy for gout and familial Mediterranean fever, this potent glucuronide derivative showcases substantial anti-inflammatory and anti-mitotic properties, offering a beacon of hope for therapeutic interventions. Synonyms: (7S)-7-(Acetylamino)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-3-yl β-D-glucopyranosiduronic acid; Thiocolchicoside glucuronide. CAS No. 819802-34-1. Molecular formula: C27H31NO11S. Mole weight: 577.60.
3-Desmorpholinyl-3-hydroxyethylamino Gefitinib
3-Desmorpholinyl-3-hydroxyethylamino Gefitinib is a metabolite of Gefitinib. Synonyms: Ethanol, 2-[[3-[[4-[(3-chloro-4-fluorophenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]propyl]aMino]-; 2-[[3-[[4-[(3-Chloro-4-fluorophenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]propyl]aMino]ethanol; Gefitinib iMpurity D; 2-((3-((4-((3-chloro-4-fluorophenyl)amino)-7-. Grade: > 95%. CAS No. 847949-56-8. Molecular formula: C20H22ClFN4O3. Mole weight: 420.87.
3'-De-tert-butoxycarbonylamino-3'-[3-(5,5-dimethyl-2,4-dioxo-1,3-oxazolidinyl)]-7,10-O-bis{[(2,2,2-trichloroethyl)oxy]carbonyl}-docetaxel is an intermediate of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: (2α,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-3-(5,5-dimethyl-2,4-dioxo-1,3-oxazolidin-3-yl)-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9-oxo-7,10-bis{[(2,2,2-trichloroethoxy)carbonyl]oxy}-5,20-epoxytax-11-en-2-yl benzoate; 3-Oxazolidinepropanoic acid, α-hydroxy-5,5-dimethyl-2,4-dioxo-β-phenyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[[(2,2,2-trichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-. Grade: ≥90%. CAS No. 160651-94-5. Molecular formula: C49H51Cl6NO19. Mole weight: 1170.64.
3'-dG-CPG
3'-dG-CPG is a modified synthetic nucleotide used in DNA synthesis for molecular biology applications. This product is widely used in research and development to study DNA-protein interactions, and is a valuable tool for drug discovery research related to gene therapy and infectious diseases. Synonyms: 5'-Dimethoxytrityl-N-dimethylformamidine-3'-deoxyGuanosine, 2'-succinoyl-long chain alkylamino-CPG. Mole weight: 329.21.
3'-dGDP
3'-dGDP is a nucleotide analog widely utilized in the biomedical sector assuming a pivotal stance in the amalgamation of DNA and RNA. Within research domains, it finds extensive employment in a multitude of investigations, ranging from comprehending DNA mending mechanisms to scrutinizing cellular reactions towards DNA impairment. Synonyms: 3'-Deoxyguanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H15N5O10P2 (free acid). Mole weight: 427.20 (free acid).
3-(D-Glucopentitol-1-yl)-1,2,4-triazolo[3,4-a]phthalazine is a derivative of triazolophthalazine with anti-inflammatory activity. Synonyms: (S)-5-C-1,2,4-Triazolo[3,4-a]phthalazin-3-yl-D-arabinitol. Grade: 96%. CAS No. 79364-50-4. Molecular formula: C14H16N4O5. Mole weight: 320.30.
3'-dGMP
3'-dGMP is a pharmaceutical compound widely utilized in the biomedical industry, exhibiting remarkable efficacy in research of combating viral infections, notably hepatitis C and HIV. Through its potent antiviral mechanisms, this invaluable substance effectively thwarts viral replication. Synonyms: 3'-Deoxyguanosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O7P (free acid). Mole weight: 347.22 (free acid).
3'-dG(N-Ac) CE Phosphoramidite
3'-dG(N-Ac) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of N-acetyl-protected deoxyguanosine (dG) at the 3'-end of DNA strands. Synonyms: 3'-dG(N-Ac) Phosphoramidite; 3'-dG(Ac) 2'-phosphoramidite; 3'-dG(Ac) 2'-amidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxyguanosine-2'-cyanoethyl phosphoramidite; 3'-dG(Ac) Phosphoramidite. Grade: ≥97%. Molecular formula: C42H50N7O8P. Mole weight: 811.88.
3'-dGTP
3'-dGTP, a nucleotide analog extensively employed in DNA and RNA molecule synthesis, is a multi-utility molecule with its applications extending to DNA replication and repair mechanisms, treating viral infections, and cancer. With its ability to act as a molecular probe, 3'-dGTP becomes a fascinating choice for exploring protein-nucleic acid interactions. Synonyms: 3'-Deoxyguanosine-5'-Triphosphate; Guanosine 5'-(tetrahydrogen triphosphate), 3'-deoxy-. Grade: ≥95% by AX-HPLC. CAS No. 55968-37-1. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol
3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: 3-(Dimethylamino)-1-(2-thienyl)-1-propanol; α-[2-(Dimethylamino)ethyl]-2-thiophenemethanol. CAS No. 13636-02-7. Molecular formula: C9H15NOS. Mole weight: 185.29.
3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder. Synonyms: 3-(Dimethylamino)-1-(2-thienyl)-1-propanone Hydrochloride. CAS No. 5424-47-5. Molecular formula: C9H14ClNOS. Mole weight: 219.73.
3-[(Dimethylamino)methyl]-2-octanone
3-[(Dimethylamino)methyl]-2-octanone is an intermediate in the synthesis of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: 2-Octanone, 3-[(dimethylamino)methyl]-. CAS No. 2514721-25-4. Molecular formula: C11H23NO. Mole weight: 185.31.
A dopamine receptor agonist. Grade: 98%. CAS No. 109140-45-6. Molecular formula: C15H23NO2.HCl. Mole weight: 285.81.
3'-Dithiol Serinol CPG
3'-Dithiol Serinol CPG, an essential chemical for solid-phase peptide synthesis, is a promising solution to the challenge of preparing disulfide-rich peptides and proteins with higher efficiency. By facilitating the construction of polypeptide chains, this chemical helps to unravel the intricate mechanisms underlying disorders including heart disease, cancer, and Alzheimer's disease at the molecular level, paving the way for targeted intervention and therapy. Synonyms: 3'-Dithiol Serinol CPG 1000Å; 3-Dimethoxytrityloxy-2-(3-((R)-α-lipoamido)propanamido)propyl-1-O-succinyl-long chain alkylamino-CPG.
3'-dT-CPG
3'-dT-CPG is an oligonucleotide support, serving as a quintessential vehicle for synthesizing DNA and RNA entities, which endows it with remarkable significance in the realm of compound. Synonyms: 5'-Dimethoxytrityl-3'-deoxyThymidine, 2'-succinoyl-long chain alkylamino-CPG. Mole weight: 304.20.
3'-dU Phosphoramidite
3'-dU Phosphoramidite is a modified uridine phosphoramidite used in oligonucleotide synthesis. It features a 5'-O-dimethoxytrityl (DMTr) group, which serves as a temporary protecting group during automated oligonucleotide assembly, and the 2'-cyanoethyl-diisopropyl phosphoramidite (2'-CED) moiety at the 3'-position, facilitating incorporation into growing oligonucleotide chains. The absence of a hydroxyl group at the 3'-position (3'-deoxy) eliminates extension from this position, often used to terminate or cap oligonucleotides selectively. This modification is particularly useful for applications requiring controlled oligonucleotide synthesis, such as chain termination studies, antisense oligonucleotides, and structural or functional RNA research. Synonyms: 5'-O-DMTr-3'-deoxyuridine 2'-CED phosphoramidite; 5-O-(4,4'-Dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,3-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 5'-O-DMTr-3'-deoxyuridine 2'-phosphoramidite; 3'-dU 2'-Phosphoramidite. Grade: ≥98%. Molecular formula: C39H47N4O8P. Mole weight: 730.80.
3-Ehylbenzophenone
3-Ethylbenzophenone is the photodegradation product of Ibuprofen and Ketoprofen in aqueous solutions. Synonyms: Ibuprofen Related Impurity; Ketoprofen Related Impurity; (3-Ethylphenyl)phenylmethanone; m-Ethylbenzophenone. Grade: > 95%. CAS No. 66067-43-4. Molecular formula: C15H14O. Mole weight: 210.28.
3'-epi-5-Chloro-2'-deoxyuridine
The 3'-enantiomer of 5-Chloro-2'-deoxyuridine. A halogenated uridine derivative used in pharmaceutical compositions. Uses: The 3'-enantiomer of 5-chloro-2'-deoxyuridine (c365235). a halogenated uridine derivative used in pharmaceutical compositions. Synonyms: 5-Chloro-1-(2-deoxy-β-D-threo-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione. CAS No. 188559-94-6. Molecular formula: C9H11ClN2O5. Mole weight: 262.65.
3-Epialexine
3-Epialexine. CAS No. 121605-56-9. Molecular formula: C8H15NO4. Mole weight: 189.21.
3'-epi-Azido-3'-deoxythymidine
3'-ent-Azido-3'-deoxythymidine is the 3'-enantiomer of 3'-Azido-3'-deoxythymidine, a potent and selective inhibitor of HIV-1 replication. Synonyms: 3'-beta-Azido-3'-deoxy thymidine; AZT(threo); AzddXyloT; NSC602670; 1-(3-beta-Azido-2,3-dideoxy-beta-D-threopentafuranosyl)thymine; 3'-ent-AZT; 3'-Epizidovudine; 3'-ent-Retrovis; 3'-ent-Retrovir; 1-(3-Azido-2,3-dideoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(3-Azido-2,3-dideoxy-β-D-threo-pentofuranosyl)thymine. Grade: ≥95%. CAS No. 73971-82-1. Molecular formula: C10H13N5O4. Mole weight: 267.24.
3'-epi-Azido-3'-deoxythymidine-d3
Labeled 3'-epi-Azido-3'deoxythymidine is an epimer of 3'-Azido-3'-deoxythymidine, a potent and selective inhibitor of HIV-1 replication. Synonyms: 1-(3-Azido-2,3-dideoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione-d3. Molecular formula: C10H10D3N5O4. Mole weight: 270.26.
3-Epicasuarine
3-Epicasuarine is an intriguing botanical extract hailing from Suillus luteus, emerging as a formidable force in the realm of cancer research. Its profound impact in related research spans across diverse cancer cells, particularly prostate cancer, wherein it triggers the elusive process of apoptosis while simultaneously hindering the relentless progression of cellular division. CAS No. 729593-71-9. Molecular formula: C8H15NO5. Mole weight: 205.21.
3'-epi-Daunorubicin
3'-epi-Daunorubicin is an analog of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (8S-cis)-8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-xylo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 3'-Epidaunorubicin; 3'-epi-Daunomycin; WP 711; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-xylo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-xylo-hexopyranoside. CAS No. 66322-65-4. Molecular formula: C27H29NO10. Mole weight: 527.52.
3'-epi-Entecavir
An impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Synonyms: 2-amino-9-((1R,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3H-purin-6(9H)-one. Grade: > 95%. Molecular formula: C12H15N5O3. Mole weight: 277.29.
3-Epi-Entecavir
3-Epi-Entecavir is an impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Synonyms: Entecavir EP Impurity B; 2-amino-9-[(1S,3S,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one; Entecavir 3-epimer. CAS No. 1367369-77-4. Molecular formula: C12H15N5O3. Mole weight: 277.284.
3'-Epi Gemcitabine
An impurity from the synthesis of Gemcitabine. Synonyms: 4-Amino-1-(deoxy-2,2-difluoro-D-threo-pentofuranosyl)-2(1H)-pyrimidinone; Gemcitabine Impurity. CAS No. 103882-85-5. Molecular formula: C9H11F2N3O4. Mole weight: 263.2.
3'-epi-Idoxuridine
The 3'-enantiomer of Idoxuridine. Antitumor nucleoside enantiomer thymidine kinase used as potential antiviral agents. Synonyms: 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-iodouracil. CAS No. 93780-25-7. Molecular formula: C9H11IN2O5. Mole weight: 354.1.
3'-epi-Taxol
3'-epi-Taxol is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: 3'-epi-Taxol; SCHEMBL15000506; (2R,3R)-3-(Benzoylamino)-2-hydroxy-3-phenylpropionic acid 1,7beta-dihydroxy-2alpha-(benzoyloxy)-4,10beta-diacetoxy-9-oxo-5beta,20-epoxytaxa-11-ene-13alpha-yl ester; [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3R)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate. Molecular formula: C47H51NO14. Mole weight: 853.90.
3-Ethoxy-4-hydroxybenzaldehyde
3-Ethoxy-4-hydroxybenzaldehyde is a flavoring agent commonly used in the production of chocolate and other foods. Synonyms: Ethyl Vanillin; 2-Ethoxy-4-formylphenol; 3-Ethylvanillin; 4-Hydroxy-3-ethoxybenzaldehyde; Arovanillon; Bourbonal; Ethavan; Ethovan; Ethylprotal; NSC 1803; NSC 67240; Protocatechuic Aldehyde Ethyl Ether; Quantrovanil; Rhodiarome; Vanillal; Vanirom. Grade: >98%. CAS No. 121-32-4. Molecular formula: C9H10O3. Mole weight: 166.17.
It is an impurity of Apremilast. Synonyms: 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine; 1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethylamine; Apremilast EP Impurity H; 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine. Grade: ≥95%. CAS No. 253168-94-4. Molecular formula: C12H19NO4S. Mole weight: 273.35.
3-Ethoxy-4-methoxybenzonitrile
It is an intermediate of Apremilast. Synonyms: Benzonitrile, 3-ethoxy-4-methoxy-; 3-ethoxy-4-methoxy-benzonitrile; 3-ethoxy-4-methoxybenzenecarbonitrile; Apremilast Impurity 2. Grade: ≥98%. CAS No. 60758-86-3. Molecular formula: C10H11NO2. Mole weight: 177.20.
Used in the synthesis of Nicotinamide Ribose and its derivatives. Synonyms: 3-(ETHOXYCARBONYL)-1-(2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)-PYRIDINIUM TRIFLATE; ethyl 1-[(2R,3R,4R,5R)-3,4-diacetyloxy-5-(acetyloxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxylate; trifluoromethanesulfonate; 3-(Ethoxycarbonyl)-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)pyridin-1-ium trifluoromethanesulfonate; DTXSID60747727; 3-(Ethoxycarbonyl)-1-(2,3,5-tri-O-acetyl-|A-D-ribofuranosyl)-pyridinium Triflate. CAS No. 936945-09-4. Molecular formula: C20H24F3NO12S. Mole weight: 559.46.
3'-Ethoxy Spinosyn L 17-pseudoaglycone
3'-Ethoxy spinosyn L 17-pseudoaglycone is an acid degradation product of 3'-ethoxy-5,6-dihydrospinosyn L which is a component of the insecticide spinosyn L. It has no insecticidal activity against the tobacco budworm up to a concentration of 64 ppm. 3'-Ethoxy spinosyn L 17-pseudoaglycone is only weakly active as an insecticide as the forosamine moiety is considered essential for potent activity. Grade: >95% by HPLC. Molecular formula: C35H54O9. Mole weight: 618.80.
3-ethyl 5-isopropyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: 3-Ethyl 5-isopropyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate. CAS No. 158151-92-9. Molecular formula: C22H29ClN2O5. Mole weight: 436.93.
3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-6-methyl-3,5-pyridinedicarboxylate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: MFCD28358808; AKOS027327287; 3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-6-methyl-3,5-pyridinedicarboxylate; SY355552; 3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-(1,3-dioxoisoindolin-2-yl)ethoxy]methyl]-6-methylpyridine-3,5-dicarboxylate. CAS No. 331258-36-7. Molecular formula: C28H25ClN2O7. Mole weight: 536.96.
3-Ethyl 5-methyl 4-(2-chlorophenyl)-2,6-bis((2-(1,3-dioxoisoindolin-2-yl)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2,6-bis[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-, 3-ethyl 5-methyl ester; 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2,6-bis[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-, ethyl methyl ester; 3-Ethyl 5-methyl 4-(2-chlorophenyl)-2,6-bis[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-3,5-pyridinedicarboxylate; 4-(2-Chlorophenyl)-2,6-bis[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-3,5-pyridinedicarboxylic Acid Ethyl 5-Methyl Ester; Ethyl methyl 4-(2-chlorophenyl)-2,6-bis{[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]methyl}-1,4-dihydro-3,5-pyridinedicarboxylate. Grade: ≥95%. CAS No. 223734-99-4. Molecular formula: C38H34ClN3O10. Mole weight: 728.14.
3-Ethylidenephthalide
3-Ethylidenephthalide is an impurity of Butylphthalide, an anti-cerebral-ischemia drug. Synonyms: 3-ethylidene-2-benzofuran-1-one. CAS No. 61658-90-0. Molecular formula: C10H8O2. Mole weight: 160.172.
3-ethylisobenzofuran-1(3H)-one
3-ethylisobenzofuran-1(3H)-one is an impurity of Butylphthalide, an anti-cerebral-ischemia drug. Synonyms: 1(3H)-Isobenzofuranone, 3-ethyl-; 3-ethylphthalide. CAS No. 17475-41-1. Molecular formula: C10H10O2. Mole weight: 162.188.
3-Ethynylaniline
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Uses: Reagent in the preparation of a metabolite of erlotinib (e625000), which is a selective epidermal growth factor receptor (egfr)-tyrosine kinase inhibitor and an antineoplastic. Synonyms: 3-ethynylaniline. Grade: > 95 %. CAS No. 54060-30-9. Molecular formula: C8H7N. Mole weight: 117.15.
3'-F-3'-dA(Bz)-2'-phosphoramidite
3'-F-3'-dA(Bz)-2'-phosphoramidite, an indispensable compound widely employed in the biomedical sector for the synthesis of oligonucleotides and nucleic acid analogs, holds paramount importance. Its modified structure renders it adept at enhancing stability, selectivity, and binding properties. Synonyms: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroadenosine-2'-CED-phosphoramidite; N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-fluorooxolan-2-yl]purin-6-yl]benzamide; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-3'-deoxy-3'-fluoroadenosine; 5'-DMT-3'-fluoro-DA(BZ) amidite; 3'-F A(Bz) 2'-amidite. Grade: ≥95%. CAS No. 2127174-09-6. Molecular formula: C47H51FN7O7P. Mole weight: 875.92.
3'-Fluorescein CPG
3'-Fluorescein CPG is a highly specialized and intricate reagent, devoted solely to the synthesis of oligonucleotides and the thriving field of biomedical research. Its fluorescent dye component makes it invaluable in the labeling and detection of DNA and RNA, exemplifying its exceptional and unique applications across various methods such as PCR and gene expression analysis. Synonyms: 3'-Fluorescein CPG 1000Å; 1-Dimethoxytrityloxy-2-(N-thiourea-(di-O-pivaloyl-fluorescein)-4-aminobutyl)-propyl-3-O-succinoyl-long chain alkylamino-CPG.
3'-Fluorescein-dT CPG
3'-Fluorescein-dT CPG, a crucial reagent in biomedicine, is indispensable for oligonucleotide and DNA probe synthesis for detecting diseases - from cancer, HIV, to genetic disorders. With its fluorescent attribute, one can visualize in vivo and in vitro the DNA probes, an invaluable resource in biomedical research. Synonyms: 5'-Dimethoxytrityloxy-5-[N-((3',6'-dipivaloylfluoresceinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-succinoyl-long chain alkylamino-CPG. Mole weight: 815.71.
3-Fluoro-4-desfluoro Bicalutamide
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: (RS)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(3-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide; Bicalutamide 3-fluoro isomer; Bicalutamide Related Compound B; Bicalutamide USP Related Compound B; USP Bicalutamide Related Compound B; 3-Fluorophenyl Bicalutamide; Bicalutamide USP RC B. Grade: >95%. CAS No. 1166228-30-3. Molecular formula: C18H14F4N2O4S. Mole weight: 430.38.
3-Fluoro-5-bromotyrosine
3-Fluoro-5-bromotyrosine is a valuable compound used in the biomedical field for drug discovery and research. It is commonly utilized to study the effects of modifications on tyrosine residues within proteins is aiding in the understanding of protein structures and functions. This compound is particularly significant in investigating diseases related to protein malfunction and developing targeted therapies for such conditions. Synonyms: 3-Bromo-5-fluorotyrosine; Jodfluortyrosin [German]; alpha-Amino-5-bromo-3-fluoro-4-hydroxybenzenepropionic acid. Grade: ≥95%. CAS No. 369-95-9. Molecular formula: C9H9BrFNO3. Mole weight: 278.07.
3'-Fluorobenzylspiperone maleate
3'-Fluorobenzylspiperone maleate is a potent and selective ligand for the dopamine D2 receptor (Ki = 0.023 nM), displaying 2.5-fold greater affinity for D2 and a 12-fold lower affinity for 5-HT2 receptors. Synonyms: 8-[4-(4-Fluorophenyl)-4-oxobutyl]-(3-fluorobenzyl-1-phenyl)-1,3,8-triazaspiro[4,5]decan-4-one maleate. Grade: ≥98% by HPLC. CAS No. 1135278-61-3. Molecular formula: C30H31F2N3O2.C4H4O4. Mole weight: 619.67.
3-Fluoro-N-acetyl-neuraminic acid
3-Fluoro-N-acetyl-neuraminic acid is a widely utilized compound, exhibiting inhibitory efficacy against various viral infections, notably influenza viruses. Distinguished for its potent antiviral attributes, it proficiently impedes viral replication. Notably, this acid selectively targets the neuraminidase enzyme within the viral entity, consequently impeding its liberation from the afflicted cells. CAS No. 921-40-4. Molecular formula: C11H18FNO9. Mole weight: 327.26.
3-Formyl-2-hydroxybenzoic Acid
3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki=120 nM), the enzyme that converts estrone sulfate to estrone. Synonyms: 3-formyl-2-hydroxybenzoic acid; 3-formyl-2-hydroxybenzoic acid. Grade: > 98 %. CAS No. 610-04-8. Molecular formula: C8H6O4. Mole weight: 166.13.
3-Formylindole-2'-deoxyriboside
3-Formylindole-2'-deoxyriboside is an indispensable biomedical entity, particularly used in research of cancer. Serving as a paramount synthetic nucleoside analog, it harmoniously orchestrates the symphony of inhibiting malignant cell proliferation. Synonyms: 1-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-indole-3-carbaldehyde; 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-1H-indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-. Grade: ≥95%. CAS No. 460355-03-7. Molecular formula: C14H15NO4. Mole weight: 261.27.
3-Formyl Rifamycin
3-Formyl Rifamycin is a metabolite of Rifampicin, a Rifamycin antibiotic. Rifampicin is a bactericidal antibiotic agent of the rifamycin group. Synonyms: 1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-8-carboxaldehyde 21-Acetate; 3-Formylrifampicin SV; NCI 145-635; Rifaldehyde; 3-formyl Rifampicin SV; Rifaldehyde; Rifamycin, 3-formyl-. Grade: > 98%. CAS No. 13292-22-3. Molecular formula: C38H47NO13. Mole weight: 725.78.
3-Fucosyllactose
3-fucosyllactose is a trisaccharide that is lactose in which the hydroxy group at position 3 of the glucosyl moiety has undergone formal condensation with the anomeric hydroxy group of fucose (6-deoxy-L-galactose) to give the corresponding glycoside. It is one of the major fucosylated oligosaccharides found in human breast milkIt, and has a role as a human metabolite. It is functionally related to a lactose. Synonyms: 3FL; Galb-4(Fuca-3)Glc; O-6-Deoxy-α-L-galactopyranosyl-(1→3)-O-[β-D-galactopyranosyl-(1→4)]-D-glucose; 3-O-α-L-Fucopyranosyllactose; 3-O-Fucosyllactose; 6-deoxy-alpha-L-galactopyranosyl-(1->3)-[beta-D-galactopyranosyl-(1->4)]-D-glucopyranose. Grade: > 90%. CAS No. 41312-47-4. Molecular formula: C18H32O15. Mole weight: 488.44.
3-Fucosyllactose-BSA
3-Fucosyllactose-BSA.
3-Galactosyllactose
3-Galactosyllactose is a galactose-derived oligosaccharide, extensively employed for studying gastrointestinal ailments. Synonyms: 3'-Galactosyllactose; 4-O-(3-O-b-D-Galactopyranosyl)-b-D-galactopyranosyl-D-glucopyranose; b-D-Gal-(1→3)-b-D-Gal-(1→4)-D-Glc; 4-beta-Laminaribiosylglucose; 4-O-(3-O-beta-D-Galactopyranosyl-beta-D-galactopyranosyl)-D-glucose; D-Glucose, O-beta-D-galactopyranosyl-(1-3)-O-beta-D-galactopyranosyl-(1-4)-. Grade: ≥90%. CAS No. 32694-82-9. Molecular formula: C18H32O16. Mole weight: 504.44.
3-Galactosyl-N-acetyl-D-lactosamine
3-Galactosyl-N-acetyl-D-lactosamine is an essential constituent in glycoprotein and glycolipid bioresearch and development assuming a pivotal function in mediating cell-cell adhesion, cellular interactions and vital cell signaling events. Revered within the biomedical realm, this compound facilitates the comprehensive exploration of glycans' structural and functional aspects, thereby unraveling their intricate involvement in manifold afflictions, existing as cancer, inflammation and autoimmune disorders. Synonyms: Galb1-3Galb1-4GlcNAc.
3-Glucosidylalternariol 9-Sulfate Ester Ammonium Salt
3'-Glyceryl CPG is a biomolecular tool that has revolutionized the biomedical industry, enabling the synthesis and modification of oligonucleotides with unrivaled efficiency and precision. Its application in antisense therapy, where targeted mRNA sequences are identified and treated with specific oligonucleotides, has led to groundbreaking advancements in the realm of cancer and genetic disorder treatment. The expansive potential of this tool is limitless, holding promise for the development of novel therapeutics that could remedy even the most complex viral infections. Synonyms: 3-[(4,4'-Dimethoxytrityoxy)glyceryl-1-succinoyl]-long chain alkylamino-CPG; 3'-Glyceryl CPG 1000Å.
3'-GMP
3'-GMP is a metabolite of guanosine-2',3'-cyclic monophosphate. Synonyms: Guanosine- 3'- O- monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 6027-83-4. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.2 (free acid).
3-Guanidinopropionic acid
3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α). 3-Guanidinopropionic acid is an acidic guanidine derivative that has been shown to ameliorate hyperglycemia in animal models of noninsulin-dependent diabetes. Synonyms: β-GPA; PNU 10483; 3-Guanidinopropanoic acid. Grade: ≥98%. CAS No. 353-09-3. Molecular formula: C4H9N3O2. Mole weight: 131.1.
3''-HABA Kanamycin A
3''-HABA Kanamycin A is an impurity of Amikacin, which is an antibacterial compound used in the treatment of diseases and illnesses arising from gram-negative bacterium. Synonyms: O-6-Amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-3-deoxy-α-D-glucopyranosyl-(1→6)]-2-deoxy-D-streptamine; Antibiotic BB-K 11; 3''-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A; Amikacin EP Impurity C; (2S)-4-amino-N-[(2S,3R,4S,5S,6R)-2-[(1S,2R,3R,4S,6R)-4,6-diamino-3-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]-2-hydroxybutanamide. Grade: ≥95%. CAS No. 50725-25-2. Molecular formula: C22H43N5O13. Mole weight: 585.60.
3-HABA Kanamycin A Sulfate
3-HABA Kanamycin A Sulfate is an impurity of Amikacin. Amikacin is an antibacterial compound used in the treatment of diseases and illnesses arising from gram-negative bacterium. Synonyms: (S)-O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N3-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine Sulfate; BB-K29 Sulfate; 3-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A Sulfate; Amikacin EP Impurity A Sulfate; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N3-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D-streptamine Sulfate. Grade: 97%. Molecular formula: C22H43N5O13.xH2SO4. Mole weight: 585.60 (free base).
3''-HABA Kanamycin A Sulfate
3''-HABA Kanamycin A Sulfate is an impurity of Amikacin. Amikacin is an antibacterial compound used in the treatment of diseases and illnesses arising from gram-negative bacterium. Synonyms: O-6-Amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-3-deoxy-α-D-glucopyranosyl-(1→6)]-2-deoxy-D-streptamine Sulfate; Antibiotic BB-K 11 Sulfate; 3''-N-[L-(-)-γ-Amino-α-hydroxybutyryl]kanamycin A Sulfate; 3''-HABA Kanamycin A Sulfate. Grade: 95%. Molecular formula: C22H43N5O13.xH2SO4. Mole weight: 585.60 (free base).
3-(Hepta-O-acetyl-b-lactopyranosyl)thio-propanoic acid is a highly intricate and multifaceted bioactive compound, emerging as a formidable contender in research of metabolic disorders, including diabetes and obesity, through its unparalleled ability to regulate glucose metabolism. This compound can effectively manipulates select enzymes implicated in pivotal metabolic pathways. Consequently, this compound serves as an indispensable instrument facilitating the investigation and targeting of metabolic dysregulation. CAS No. 152435-15-9. Molecular formula: C29H40O19S. Mole weight: 724.69.
An impurity of Orlistat. Orlistat is a pancreatic lipase inhibitor that aids in weight loss by blocking the absorption of dietary fats in the gastrointestinal tract. Synonyms: Orlistat THL-Delta Lactone; 3-Hexyl-4-hydroxy-6-undecyltetrahydro-2H-pyran-2-one; Orlistat Impurity 70. Grade: ≥95%. CAS No. 104801-94-7. Molecular formula: C22H42O3. Mole weight: 354.57.
3-Hydroxy-1-azabicyclo[2.2.2]octane-3-methanol
3-Hydroxy-1-azabicyclo[2.2.2]octane-3-methanol is an impurity of Cevimeline hydrochloride which is a selective M1 receptor agonist. Synonyms: 3-hydroxymethyl-3-quinuclidinol. CAS No. 61573-79-3. Molecular formula: C8H15NO2. Mole weight: 157.21.
3-Hydroxy-2,6,6-trimethyl-1-cyclohexene-1-carbonitrile is an intermediate in the preparation of Retinoic Acid derivatives. Synonyms: (+)-3-Hydroxy-2,6,6-trimethyl-1-cyclohexene-1-carbonitrile; 3-Hydroxy-2,6,6-trimethylcyclohex-1-ene-1-carbonitrile; 1-Cyclohexene-1-carbonitrile, 3-hydroxy-2,6,6-trimethyl-. Grade: ≥90%. CAS No. 145106-79-2. Molecular formula: C10H15NO. Mole weight: 165.23.
3-Hydroxy-2-methylbutyryl-CoA
3-Hydroxy-2-methylbutyryl-CoA is an intermediate in the metabolization of Isoleucine to 2-Methylbutyryl-CoA. Synonyms: S-(3-Hydroxy-2-methylbutyrate) Coenzyme A; S-(3-Hydroxy-2-methylbutanoate) Coenzyme A; 2-Methyl-3-hydroxybutyryl-CoA. CAS No. 6701-38-8. Molecular formula: C26H44N7O18P3S. Mole weight: 867.65.
3-Hydroxy-2-methylpyridine
An impurity of Pantoprazole, which is a prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD). Synonyms: 3-Pyridinol, 2-methyl-; 2-Methyl-3-pyridinol; 2-Methyl-3-hydroxypyridine; NSC 27506. Grade: ≥95%. CAS No. 1121-25-1. Molecular formula: C6H7NO. Mole weight: 109.13.
3-Hydroxy-3-Butylphthalide
3-Hydroxy-3-Butylphthalide is an impurity of Butylphthalide, an anti-cerebral-ischemia drug. Synonyms: 1(3H)-Isobenzofuranone, 3-butyl-3-hydroxy-. CAS No. 162050-42-2. Molecular formula: C12H14O3. Mole weight: 206.241.
3-Hydroxy-3-methylglutaric acid
3-Hydroxy-3-methylglutaric acid is a hypolipidemic agent which inhibits the activity of hydroxymethylglutarryl CoA reductases. Uses: A hypolipidemic agent. Synonyms: β-Hydroxy-β-methylglutaric acid; Meglutol; Dicrotalic acid. Grade: ≥ 95 %. CAS No. 503-49-1. Molecular formula: C6H10O5. Mole weight: 162.14.
3-Hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxobutanoic acid is an impurity of Phenylephrine, which is a selective α1-adrenergic receptor agonist used as a nasal decongestant and cardiotonic agent. Synonyms: Butanoic acid, 3-hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxo-; 3-hydroxy-4-(((R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl)(methyl)amino)-4-oxobutanoic acid; Phenylephrine Related Compound; Phenylephrine Impurity 31 (Mixture of Diastereomers); N-Methyl-N-[(βR)-β,3-dihydroxyphenethyl]-3-hydroxysuccinamidic acid. Grade: ≥95%. CAS No. 830346-80-0. Molecular formula: C13H17NO6. Mole weight: 283.28.