BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester | 4-[2'-(7''-Deazaguanine)ethyl]benzoic acid N-hydroxysuccinimide ester is an intermediate of Pemetrexed, which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Synonyms: Pemetrexed Impurity; Benzoic acid, 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate; 2,5-Pyrrolidinedione, 1-[[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]oxy]-; 2,5-Dioxopyrrolidin-1-yl 4-(2-(2-imino-4-oxo-2,3,4,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate; 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; 1-[[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]oxy]-2,5-pyrrolidinedione. Grade: ≥95%. CAS No. 204257-65-8. Molecular formula: C19H17N5O5. Mole weight: 395.38. |  |
| 4-((2-amino-2-oxoethyl)(hydroxy)amino)butanoic acid | 4-((2-amino-2-oxoethyl)(hydroxy)amino)butanoic acid is an impurity of Piracetam, which is a typical nootropic. CAS No. 2454698-45-2. Molecular formula: C6H12N2O4. Mole weight: 176.17. | |
| 4-(2-(Benzyl(methyl)amino)-1-hydroxyethyl)-2-(benzyloxy)phenyl (2,2,2-trichloroethyl) Sulfate | An intermediate of Epinephrine Sulfate. Epinephrine is an endogenous catcholamine with combined α-and β-agonist activity and its principal sympathomimetic hormone is produced by the adrenal medulla. Synonyms: 4-{2-[Benzyl(methyl)amino]-1-hydroxyethyl}-2-(benzyloxy)phenyl 2,2,2-trichloroethyl sulfate; Sulfuric acid, 4-[1-hydroxy-2-[methyl(phenylmethyl)amino]ethyl]-2-(phenylmethoxy)phenyl 2,2,2-trichloroethyl ester. Molecular formula: C25H26Cl3NO6S. Mole weight: 574.90. | |
| 4-(2-Bromoacetyl)phenyl acetate | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Ethanone, 1-[4-(acetyloxy)phenyl]-2-bromo-. CAS No. 41104-10-3. Molecular formula: C10H9BrO3. Mole weight: 257.08. | |
| 4-(2'-Bromoethyl)-3-chloro-1,3-dihydro-2-indoline-2-one | An intermediate of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Synonyms: 4-(2-Bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one. Grade: 95%. CAS No. 120427-95-4. Molecular formula: C10H9BrClNO. Mole weight: 274.54. | |
| 4-((2-chloro-4-hydroxyphenyl)amino)-7-methoxyquinoline-6-carboxamide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Synonyms: Lenvatinib Impurity 02; 6-Quinolinecarboxamide, 4-[(2-chloro-4-hydroxyphenyl)amino]-7-methoxy-. CAS No. 2380197-89-5. Molecular formula: C17H14ClN3O3. Mole weight: 343.76. | |
| 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine | 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomer of SSR-125543 that is an effective CRF-R1 antagonist with Ki=1.0 nM against human CRF-R1. Grade: >98.0%. CAS No. 2649012-21-3. Molecular formula: C27H28ClFN2OS. Mole weight: 483.04. | |
| 4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite | 4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite is a phosphoramidite compound, utilized in the biomedical industry for the synthesis of modified oligonucleotides, specifically in the field of nucleic acid research and drug development. It serving as a key component for the introduction of 4-(2-cyanoethylthio)-2'-deoxy-5'-DMT-uridine nucleotide residues during DNA or RNA synthesis. These modified nucleotides find applicability in the development of therapeutics, diagnostics is and nucleic acid-based tools for targeting various diseases. Molecular formula: C42H50N5O7PS. Mole weight: 799.93. | |
| 4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite | 4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite, a vital asset in the biomedical sector, serves as an indispensable tool for facilitating DNA synthesis. As a pivotal constituent in the fabrication of oligonucleotides, this phosphoramidite compound assumes a prominent role in addressing diverse genetic ailments. Its exceptional attributes bestow upon it the prowess to effectively construct DNA sequences employed in the realms of diagnostics, drug exploration, and targeted healing interventions. Molecular formula: C43H52N5O7PS. Mole weight: 813.96. | |
| 4-[2-(Dimethylamino)ethoxy]benzaldehyde | 4-[2-(Dimethylamino)ethoxy]benzaldehyde is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: p-[2-(Dimethylamino)ethoxy]benzaldehyde; 4-(N,N-dimethylaminoethoxy)benzaldehyde; 4-(2-dimethylamino-1-ethoxy)benzaldehyde; Benzaldehyde, 4-[2-(dimethylamino)ethoxy]-. Grade: ≥95%. CAS No. 15182-92-0. Molecular formula: C11H15NO2. Mole weight: 193.24. | |
| 4-(2-(dimethylamino)ethyl)benzene-1,2-diol hydrobromide | 4-(2-(dimethylamino)ethyl)benzene-1,2-diol hydrobromide is a metabolite of Dopamine. Synonyms: 4-[2-(dimethylamino)ethyl]benzene-1,2-diol hydrobromide; 4-[2-(dimethylamino)ethyl]benzene-1,2-diol; hydrobromide; 4-(2-(dimethylamino)ethyl)benzene-1,2-diol hydrobromide; N,N-dimethyldopamine hydrobromide; SCHEMBL20854749; DTXSID70851364; EN300-116779; 4-[2-(dimethylamino)ethyl]benzene-1,2-diolhydrobromide; Z1501469796; 4-[2-(Dimethylamino)ethyl]benzene-1,2-diol--hydrogen bromide (1/1). CAS No. 50309-53-0. Molecular formula: C10H16BrNO2. Mole weight: 262.14. | |
| 4-[2-(Dipropylamino)ethyl]-1H-indole-2,3-dione 3-oxime | An impurity of Ropinirole. Ropinirole is a non-ergot dopamine agonist that acts primarily on D2 and D3 receptors. It is used to treat Parkinson's disease and restless legs syndrome by mimicking the action of dopamine in the brain. Synonyms: 1H-Indole-2,3-dione, 4-[2-(dipropylamino)ethyl]-, 3-oxime; Ropinirole EP Impurity H (E/Z mixture); Ropinirole oxime; 3-Hydroxyimino Ropinirole. Grade: ≥95%. CAS No. 2734474-99-6. Molecular formula: C16H23N3O2. Mole weight: 289.37. | |
| 4'-((2-ethoxy-7-(methoxycarbonyl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid | 4'-((2-ethoxy-7-(methoxycarbonyl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid is an impurity of Azilsartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Synonyms: 4'-((2-Ethoxy-7-(methoxycarbonyl)-1h-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid; 4'-((2-Ethoxy-7-(methoxycarbonyl)-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid; F19388. CAS No. 1675221-59-6. Molecular formula: C25H22N2O5. Mole weight: 430.45. | |
| 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid | 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid is an impurity of Olmesartan Medoxomil. Olmesartan Medoxomil is an angiotensin II receptor antagonist which has been used for the treatment of high blood pressure. It is a metabolite of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. hAT1 receptors: IC50 = 6.18 nM. Synonyms: 4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid. CAS No. 144690-04-0. Molecular formula: C10H16N2O3. Mole weight: 212.25. | |
| 4-(2-Methoxyethyl)aniline | 4-(2-Methoxyethyl)aniline is a biomedical compound exhibiting immense potential in studying a myriad of ailments. Remarkably, it serves as a pivotal building block in the intricate synthesis of pharmaceutical agents that diligently tackle formidable adversaries like cardiovascular pathologies, neurological irregularities and even the ruthless scourge of cancer. Uses: Used in the synthesis of selective β-adrenergic blocker metoprolol. Synonyms: 4-(2-Methoxyethyl)benzenamine; p-2-Methoxyethyl-Aniline; 1-Methoxy-2-(4-aminophenyl)ethane; 4-(2-Methoxyethyl)phenylamine; p-(2-Methoxyethyl)aniline; 4-methoxyethylaniline. Grade: ≥95%. CAS No. 84803-56-5. Molecular formula: C9H13NO. Mole weight: 151.21. | |
| 4-(2-Methoxyethyl)phenol | 4-(2-Methoxyethyl)phenol is an impurity of Metoprolol. Synonyms: Phenol, 4-(2-methoxyethyl)-; Phenol, p-(2-methoxyethyl)-; p-(2-Methoxyethyl)phenol; p-Hydroxyphenethyl methyl ether; Metoprolol Impurity I; Metoprolol Impurity B; Metoprolol EP Impurity B. Grade: ≥95%. CAS No. 56718-71-9. Molecular formula: C9H12O2. Mole weight: 152.19. | |
| 4-(2-Methyl-1-pyrrolidyl)-7-chloroquinoline | An impurity of Hydroxychloroquine. Hydroxychloroquine is a quinoline medication primarily used to prevent or treat malaria and manage certain autoimmune diseases such as rheumatoid arthritis and lupus erythematosus. Synonyms: Hydroxychloroquine Sulfate Impurity F; 7-Chloro-4-(2-methyl-1-pyrrolidinyl)quinoline; 7-Chloro-4-(2-methyltetrahydropyrrolyl)quinoline; NSC 5820. Grade: ≥95%. CAS No. 6281-58-9. Molecular formula: C14H15ClN2. Mole weight: 246.74. | |
| 4'-[[[2-Methyl-4-(1-methyl-1H-benzimidazol-2-yl)-6-nitrophenyl](1-oxobutyl)amino]methyl]-[1,1'-biphenyl]-2-carboxylic Acid Methyl Ester | 4'-[[[2-Methyl-4-(1-methyl-1H-benzimidazol-2-yl)-6-nitrophenyl](1-oxobutyl)amino]methyl]-[1,1'-biphenyl]-2-carboxylic Acid Methyl Ester is one of telmisartan impurities. Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension. CAS No. 1338830-33-3. Molecular formula: C34H32N4O5. Mole weight: 576.64. | |
| 4-(2-(methylamino)ethyl)benzene-1,2-diol hydrobromide | 4-(2-(methylamino)ethyl)benzene-1,2-diol hydrobromide is a metabolite of Dopamine. Synonyms: 4-[2-(Methylamino)ethyl]-1,2-benzenediol hydrobromide (1:1). CAS No. 18191-22-5. Molecular formula: C9H14BrNO2. Mole weight: 248.12. | |
| 4-(2-Methylimidazole-1-yl)-2,2-diphenylbutyronitrile phosphate | 4-(2-Methylimidazole-1-yl)-2,2-diphenylbutyronitrile phosphate is an impurity of Imidafenacin, which is a potent and selective inhibitor of M3 receptors. Synonyms: 1H-Imidazole-1-butanenitrile, 2-methyl-α,α-diphenyl-, phosphate (1:1); Imidafenacin Impurity; 1-(3-Cyano-3,3-diphenylpropyl)-2-methyl-1H-imidazolium phosphate; 4-(2-Methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile phosphate (1:1). Grade: ≥95%. CAS No. 562091-56-9. Molecular formula: C20H22N3O4P. Mole weight: 399.39. | |
| 4',2''-O-Di(trimethysilyl)tylosin | 4',2''-O-Di(trimethysilyl)tylosin is a reactant used in the antibacterial Tylosin derivatives preparation process. Synonyms: 2A,4C-Bis-O-(trimethylsilyl)-tylosin. CAS No. 114442-77-2. Molecular formula: C52H93NO17Si2. Mole weight: 1060.46. | |
| 4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester | 4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: Ethyl 4-(2-Phthalimidoethoxy)acetoacetate; 4-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester; 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester. Grade: >95%. CAS No. 88150-75-8. Molecular formula: C16H17NO6. Mole weight: 319.31. | |
| 4-(2-Piperidinoethoxy)benzoic acid | 4-(2-Piperidinoethoxy)benzoic acid. Synonyms: 4-[2-(1-Piperidinyl)ethoxy]benzoic acid; 4-(2-(Piperidin-1-yl)ethoxy)benzoic acid. Grade: >95%. CAS No. 89407-98-7. Molecular formula: C14H19NO3. Mole weight: 249.31. | |
| 4-(2-Piperidinoethoxy)benzoic acid hydrochloride | 4-(2-Piperidinoethoxy)benzoic acid hydrochloride. Synonyms: Benzoic acid, 4-[2-(1-piperidinyl)ethoxy]-, hydrochloride (1:1); Benzoic acid, 4-[2-(1-piperidinyl)ethoxy]-, monohydrochloride; 1-(2-(4-Carboxyphenoxy)ethyl)piperidin-1-ium chloride; 4-[2-(1-Piperidinyl)ethoxy]benzoic acid hydrochloride. Grade: >95%. CAS No. 84449-80-9. Molecular formula: C14H19NO3.HCl. Mole weight: 285.77. | |
| 4-(2-Pyridinyl)benzaldehyde | 4-(2-Pyridinyl)benzaldehyde is an impurity of Atazanavir, which is a potent azapeptide protease inhibitor used as an antiretroviral medication for the treatment of HIV/AIDS. Synonyms: Atazanavir impurity; Benzaldehyde, 4-(2-pyridinyl)-; 2-(4-Formylphenyl)pyridine; 2-(4'-Formylphenyl)pyridine; 2-(p-Formylphenyl)pyridine; 4-(2-Pyridyl)benzaldehyde; Pyridinyl benzaldehyde. Grade: ≥95%. CAS No. 127406-56-8. Molecular formula: C12H9NO. Mole weight: 183.21. | |
| 4-(2-Pyridinyl)benzoic acid | 4-(2-Pyridinyl)benzoic acid is an impurity of Atazanavir, which is a potent azapeptide protease inhibitor used as an antiretroviral medication for the treatment of HIV/AIDS. Synonyms: Benzoic acid, 4-(2-pyridinyl)-; Atazanavir Impurity (Pyridinyl Benzoic Acid); Benzoic acid, p-2-pyridyl-; 4-(2-Pyridyl)benzoic acid; 4-(Pyridin-2-yl)benzoic acid. Grade: ≥95%. CAS No. 4385-62-0. Molecular formula: C12H9NO2. Mole weight: 199.21. | |
| 4-(2-(tert-butylamino)-1-ethoxyethyl)-2-(ethoxymethyl)phenol | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Salbutamol Diethyl Ether; Phenol, 4-[2-[(1,1-dimethylethyl)amino]-1-ethoxyethyl]-2-(ethoxymethyl)-. CAS No. 1221726-71-1. Molecular formula: C17H29NO3. Mole weight: 295.42. | |
| 4-(2-(tert-Butylamino)-1-methoxyethyl)-2-(methoxymethyl)phenol | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Albuterol dimethyl ether; Phenol, 4-[2-[(1,1-dimethylethyl)amino]-1-methoxyethyl]-2-(methoxymethyl)-. CAS No. 870076-73-6. Molecular formula: C15H25NO3. Mole weight: 267.36. | |
| 4-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic Acid | 4-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic Acid is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: FK3XE7RE3S; 4-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic AcidEthyl Ester; UNII-FK3XE7RE3S; 4-[[3-[2-(3-CHLOROPHENYL)ETHYL]-2-PYRIDINYL]CARBONYL]-1-PIPERIDINECARBOXYLIC ACID; Ethyl 4-((3-(2-(3-chlorophenyl)ethyl)-2-pyridinyl)carbonyl)-1-piperidinecarboxylate; ethyl 4-[3-[2-(3-chlorophenyl)ethyl]pyridine-2-carbonyl]piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-((3-(2-(3-chlorophenyl)ethyl)-2-pyridinyl)carbonyl)-, ethyl ester; FT-0664878. Molecular formula: C20H21ClN2O3. Mole weight: 372.84. | |
| 4-(3-(2,3-O-Isopropylidene-lyxofuranos-5-yl)propan-2-one-1-yl)piperidine-2,6-dione | Isopropylidene-Lyxofuranosyl Piperidine-2,6-dione's unique structure and pharmacological properties make it a suitable candidate for drug development targeting specific cellular pathways involved in diseases like cancer, inflammation, and neurodegenerative disorders. Extensive research is ongoing to unravel the therapeutic potential and mechanism of action of this compound in treating these conditions. Synonyms: 5-deoxy-2,3-O-isopropylidene-5-((2,6-piperidinedione-4-yl)propane-2-on-1-yl)-D-lyxofuranose. Molecular formula: C16H23NO8. Mole weight: 357.36. | |
| 4-(3-(4-butyrylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one | 4-(3-(4-butyrylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4-{3-[(4-Butyryl-1-piperazinyl)carbonyl]-4-fluorobenzyl}-1(2H)-phthalazinone. CAS No. 2250243-17-3. Molecular formula: C24H25FN4O3. Mole weight: 436.48. | |
| 4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one | 4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one is an impurity of olaparib, which selectively binds and inhibits PARP, inhibiting PARP-mediated repair of single-strand DNA breaks. Synonyms: 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-benzoyl]piperazine. CAS No. 763113-06-0. Molecular formula: C24H24N4O3. Mole weight: 416.47. | |
| 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenaminehydrochloride | 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride is a remarkable pharmaceutical compound functioning as a selectively potent serotonin reuptake inhibitor (SSRI). It has garnered medical interest for its significant contributions to the research of depression and anxiety disorders. CAS No. 79617-89-3. | |
| 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-1-methylethyl ester benzoic acid | 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-1-methylethyl ester benzoic acid is an impurity of Deferasirox. Deferasirox is an oral iron chelator used to treat chronic iron overload in patients receiving long term blood transfusions. Synonyms: Deferasirox Isopropyl ester. CAS No. 1266741-29-0. Molecular formula: C24H21N3O4. Mole weight: 415.44. | |
| 4-(3,5-bis-(Trifluoromethyl)-1H-pyrazol-1-yl)phenylamine | A Pyrazol derivative which could be used to product one of the CRAC inhibitor as an intermediate. Uses: A pyrazol derivative which could be used to product one of the crac inhibitor as an intermediate. Synonyms: 4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-phenylamine. Grade: 95%. CAS No. 123066-64-8. Molecular formula: C11H7F6N3. Mole weight: 295.18. | |
| 4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-6-[(1-methyl-2-pyrrolidinylidene)amino]-3-quinolinecarbonitrile | An impurity of Neratinib, which is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Synonyms: Neratinib Impurity PRQ; 3-Quinolinecarbonitrile, 4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-6-[(1-methyl-2-pyrrolidinylidene)amino]-. Grade: ≥95%. CAS No. 1144516-21-1. Molecular formula: C29H27ClN6O2. Mole weight: 527.02. | |
| 4-(3-chloro-4-(3,3-dimethylureido)phenoxy)-7-methoxyquinoline-6-carboxamide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Synonyms: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(dimethylamino)carbonyl]amino]phenoxy]-7-methoxy-; Lenvatinib Impurity 07. CAS No. 2143930-76-9. Molecular formula: C20H19ClN4O4. Mole weight: 414.84. | |
| 4-(3-chloro-4-(3-methylureido)phenoxy)-7-methoxyquinoline-6-carboxamide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Synonyms: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(methylamino)carbonyl]amino]phenoxy]-7-methoxy-; Lenvatinib Impurity 06. CAS No. 417719-45-0. Molecular formula: C19H17ClN4O4. Mole weight: 400.82. | |
| 4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(2-hydroxy-5-oxopyrrolidin-1-yl)quinoline-3-carbonitrile | An impurity of Neratinib, which is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity. Synonyms: Quinoline-3-carbonitrile, 4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(2-hydroxy-5-oxopyrrolidin-1-yl); Neratinib Impurity 14. Grade: ≥95%. CAS No. 1144516-15-3. Molecular formula: C28H24ClN5O4. Mole weight: 529.98. | |
| 4-(3-Chloroanilino)quinazoline | It is a potent inhibitor of Epidermal growth factor receptor erbB1 with IC50 = 23 nM. Synonyms: N-(3-Chlorophenyl)-4-quinazolinamine; (3-chlorophenyl)-quinazolin-4-yl-amine. Grade: 98%. CAS No. 88404-44-8. Molecular formula: C14H10ClN3. Mole weight: 255.70. | |
| 4-(3-fluoro-4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide | An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. CAS No. 2188236-16-8. Molecular formula: C21H16F4N4O3. Mole weight: 448.4. | |
| 4-(3-Hydroxypropyl)phenyl β-D-Glucopyranosiduronic Acid | 4-(3-Hydroxypropyl)phenyl β-D-Glucopyranosiduronic Acid is used in biological studies for biodistribution and elimination of xenoestrogen nonylphenol in Wistar rats. Synonyms: 4-(3-Hydroxypropyl)phenyl beta-D-Glucopyranosiduronic Acid. CAS No. 549548-40-5. Molecular formula: C15H20O8. Mole weight: 328.31. | |
| 4-(3-Methoxypropoxy)-3-methylpicolinic Acid | An impurity of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Synonyms: 4-(3-Methoxypropoxy)-3-methyl-2-pyridinecarboxylic Acid; Des Benzimidazolosulfoxy Rabeprazole Acid; Rabeprazole Impurity 3; Rabeprazole Impurity-III. Grade: > 95%. CAS No. 1163685-31-1. Molecular formula: C11H15NO4. Mole weight: 225.25. | |
| 4-(3-methyl-4-phenylisoxazol-5-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 39; Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)-. Grade: 98%. CAS No. 181695-84-1. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 4-(4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Synonyms: 1-(4-(6-carbamoyl-7-methoxyquinolin-4-yloxy)phenyl)-3-cyclopropylurea; Lenvatinib Impurity 03. CAS No. 417714-14-8. Molecular formula: C21H20N4O4. Mole weight: 392.41. | |
| 4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-benzyl-1-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazin-1-ium | 4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-benzyl-1-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazin-1-ium is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 1819334-66-1. Molecular formula: C57H70F2N10O42. Mole weight: 997.25. | |
| 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 171228-51-6. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 1229428-91-4. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243785-96-6. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 213381-06-7. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one | 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. CAS No. 2243785-99-9. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. | |
| 4,4,4-Trimethoxybutanoic Acid Methyl Ester | 4,4,4-Trimethoxybutanoic Acid Methyl Ester is the substituent in the synthesis of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: Butanoic acid, 4,4,4-trimethoxy-, methyl ester. Grade: ≥95%. CAS No. 71235-00-2. Molecular formula: C8H16O5. Mole weight: 192.21. | |
| 4,4'-(5-methylisoxazole-3,4-diyl)dibenzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 15; Valdecoxib Impurity 13. CAS No. 2251048-58-3. Molecular formula: C16H15N3O5S2. Mole weight: 393.43. | |
| 4-(4-((6-carbamoyl-7-methoxyquinolin-4-yl)amino)-3-chlorophenoxy)-7-methoxyquinoline-6-carboxamide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Synonyms: Lenvatinib Impurity 01. CAS No. 2380197-90-8. Molecular formula: C28H22ClN5O5. Mole weight: 543.96. | |
| 4-(4-Aminophenoxy)-2-pyridinecarboxamide | 4-(4-Aminophenoxy)-2-pyridinecarboxamide is one of Sorafenib intermediates. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-(2-Carbamoyl-4-pyridyloxy)aniline; 4-(4-Aminophenoxy)picolinamide; 4-(4-amino-phenoxy)-pyridine-2-carboxylic acid amide; 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-; Sorafenib tosylate Impurity 8; 4-(2-carbamoyl-pyridin-4-yloxy)aniline. Grade: 95%. CAS No. 284462-80-2. Molecular formula: C12H11N3O2. Mole weight: 229.23. | |
| 4-(4-Aminophenoxy)picolinic Acid | 4-(4-Aminophenoxy)picolinic Acid is used in the synthesis of sorafenib analogs. Synonyms: 4-(4-Aminophenoxy)-2-pyridinecarboxylic Acid; Sorafenib Related Compound 19. Grade: 98%. CAS No. 1012058-77-3. Molecular formula: C12H10N2O3. Mole weight: 230.22. | |
| 4'-[[4-(Azidomethyl)-2-butyl-5-chloro-1H-imidazol-1-yl]methyl][1,1'-biphenyl]-2-carbonitrile | An impurity of Losartan. Losartan is an angiotensin II receptor blocker (ARB) primarily used to treat hypertension, reduce the risk of stroke in patients with left ventricular hypertrophy, and manage diabetic nephropathy in patients with type 2 diabetes and elevated serum creatinine levels. Synonyms: 4'-((4-(Azidomethyl)-2-butyl-5-chloro-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile; Losartan Impurity 2 (isomer azide nitrile); LTP-I Azide Isomer. Grade: ≥95%. CAS No. 2755908-49-5. Molecular formula: C22H21ClN6. Mole weight: 404.90. | |
| 4,4'-(((carbonylbis(azanediyl))bis(3-chloro-4,1-phenylene))bis(oxy))bis(7-methoxyquinoline-6-carboxamide) | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β. Synonyms: 1,3-bis(4-(6-carbamoyl-7-methoxyquinolin-4-yloxy)-2-chlorophenyl)urea; 4,4'-[Carbonylbis[imino(3-chloro-4,1-phenylene)oxy]]bis[7-methoxy-6-quinolinecarboxamide]; Lenvatinib Impurity 04. CAS No. 2143930-75-8. Molecular formula: C35H26Cl2N6O7. Mole weight: 713.52. | |
| 4-(4-Chlorobutyl)pyridine Hydrochloride | One of the impurities of Tirofiban, which has been found to be a glycoprotein IIb/IIIa inhibitor and could be used as an antiplatelet agent. Synonyms: 4-(4-chlorobutyl)pyridine; hydrochloride; 4-(4-chlorobutyl)pyridine; hydrochloride. CAS No. 149463-65-0. Molecular formula: C9H13Cl2N. Mole weight: 206.11. | |
| 4-(4-chlorophenyl)-5-methyl-3-phenylisoxazole | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 40. CAS No. 1448355-87-0. Molecular formula: C16H12ClNO. Mole weight: 269.72. | |
| 4-(4-Chlorophenyl)cyclohexanecarboxylic acid | 4-(4-Chlorophenyl)cyclohexanecarboxylic acid is an intermediate of Atovaquone, which is a medication used to treat or prevent pneumocystis pneumonia, toxoplasmosis, malaria, and babesia. Synonyms: Cyclohexanecarboxylic acid, 4-(4-chlorophenyl)-; 4-(4-Chlorophenyl)-1-cyclohexanecarboxylic acid. Grade: 95%. CAS No. 95233-37-7. Molecular formula: C13H15ClO2. Mole weight: 238.71. | |
| 4-[(4-Chlorophenyl)methyl]-2-(1-methyl-2-pyrrolidinyl)-1(2H)-phthalazinone | An impurity of Azelastine. Azelastine is a selective histamine H1 receptor antagonist used primarily for the treatment of allergic rhinitis and perennial rhinitis, including the relief of nasal congestion, runny nose, sneezing and itchy nose. Grade: ≥95%. CAS No. 53242-89-0. Molecular formula: C20H20ClN3O. Mole weight: 353.85. | |
| 4-(4-Cyclopropyl-1-naphthyl)-1,2,4-triazole-5(4H)-thione | 4-(4-Cyclopropyl-1-naphthyl)-1,2,4-triazole-5(4H)-thione is an intermediate of Lesinurad, a HEK293 cell-based inhibitor. Synonyms: 4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol; 4-(4-cyclopropyl-1-naphthalenyl)-1H-1,2,4-triazole-5-thione; 4-(4-Cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione. Grade: >95%. CAS No. 1533519-84-4. Molecular formula: C15H13N3S. Mole weight: 267.35. | |
| 4',4'-Dibromomethyl Biphenyl-2-Carboxylic Acid | 4',4'-Dibromomethyl Biphenyl-2-Carboxylic Acid is one of telmisartan impurities. Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension. Synonyms: 4'-(dibromomethyl)-[1,1'-biphenyl]-2-carboxylic acid; Telmisartan Dibromo Acid Impurity. Grade: 98%. CAS No. 1797894-62-2. Molecular formula: C14H10Br2O2. Mole weight: 370.04. | |
| 4,4'-Dimethoxybenzophenone-[d8] | 4,4'-Dimethoxybenzophenone-[d8]. Synonyms: 4,4'-Dimethoxybenzophenone-d8. Grade: 98% atom D. CAS No. 350818-55-2. Molecular formula: C15H6D8O3. Mole weight: 250.32. | |
| 4,4'-Dimethoxychalcone | It acts as a natural autophagy inducer with anti-ageing properties. Synonyms: 1,3-bis(4-methoxyphenyl)prop-2-en-1-one; (2E)-1,3-bis(4-methoxyphenyl)prop-2-en-1-one; (E)-4,4'-Dimethoxychalcone; NSC 87339. Grade: 95%. CAS No. 2373-89-9. Molecular formula: C17H16O3. Mole weight: 268.31. | |
| 4,4-Dimethyl-7-ethynyl-1-tetralone | 4,4-Dimethyl-7-ethynyl-1-tetralone is a pharmaceutical compound used in the research of various diseases, including cancer and neurodegenerative disorders. Uses: Intermediate in the production of high affinity retinoic acid receptor (rar) antagonists. Synonyms: 7-Ethynyl-3,4-dihydro-4,4-dimethyl-1(2H)-naphthalenone; 7-Ethynyl-4,4-dimethyl-3,4-dihydronaphthalen-1(2H)-one; 1(2H)-Naphthalenone, 7-ethynyl-3,4-dihydro-4,4-dimethyl-; 7-Ethynyl-4,4-dimethyl-3,4-dihydro-1(2H)-naphthalenone; 7-Ethynyl-4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-one. Grade: ≥95%. CAS No. 166978-48-9. Molecular formula: C14H14O. Mole weight: 198.26. | |
| 4,4-Dimethyl-7-methoxyisochroman-1,3-dione | 4,4-Dimethyl-7-methoxyisochroman-1,3-dione is an impurity of Gliquidone, which is an ATP-sensitive K+ channel antagonist. Synonyms: 7-Methoxy-4,4-dimethyl-1H-2-benzopyran-1,3(4H)-dione; 1H-2-Benzopyran-1,3(4H)-dione, 7-methoxy-4,4-dimethyl-; 7-Methoxy-4,4-dimethyl-1,3-isochromandione; 7-Methoxy-4,4-dimethyl-3,4-dihydro-1H-2-benzopyran-1,3-dione. Grade: 95%. CAS No. 55974-25-9. Molecular formula: C12H12O4. Mole weight: 220.22. | |
| 4-[4-(Dimethylamino)phenyl]-1,2,4-triazolidine-3,5-dione | 4-[4-(Dimethylamino)phenyl]-1,2,4-triazolidine-3,5-dione is a new reagent for determination of ultra trace amounts of Thallium(III). Synonyms: 4-(4'-N,N-Dimethylaminophenyl)urazole. Grade: > 95%. CAS No. 883455-55-8. Molecular formula: C10H12N4O2. Mole weight: 220.23. | |
| 4,4-Dimethyldihydrofuran-2,3-dione | An impurity of Dexpanthenol which acts as a precursor of coenzyme A necessary for acetylation reactions. Uses: 4,4-dimethyldihydrofuran-2,3-dione (cas# 13031-04-4) is a useful research chemical. Synonyms: 4,4-dimethyloxolane-2,3-dione; 4,4-dimethyloxolane-2,3-dione. Grade: > 95 %. CAS No. 13031-04-4. Molecular formula: C6H8O3. Mole weight: 128.13. | |
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