BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 4-Phenylmethoxy Entecavir | Used in the preparation of Entecavir for treating hepatitis B. Synonyms: 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-3-(hydroxymethyl)-2-methylene-4-(phenylmethoxy)cyclopentyl]-6H-purin-6-one. CAS No. 1030919-51-7. Molecular formula: C19H21N5O3. Mole weight: 367.4. |  |
| 4-PPBP maleate salt | 4-PPBP, a piperidine derivative, is a σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes. It is used as a cosmetic process for treating wrinkled skin, in particular the skin of the face and/or of the forehead, through a dermo-decontracting effect. Synonyms: Piperidine, 4-phenyl-1-(4-phenylbutyl)-, (2Z)-2-butenedioate (1:x); Piperidine, 4-phenyl-1-(4-phenylbutyl)-, (Z)-2-butenedioate. Grade: ≥95%. CAS No. 207572-62-1. Molecular formula: C21H27N.xC4H4O4. Mole weight: 293.45 (free base). | |
| 4-PPBP monomaleate salt | 4-PPBP, a piperidine derivative, is a σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes. It is used as a cosmetic process for treating wrinkled skin, in particular the skin of the face and/or of the forehead, through a dermo-decontracting effect. Synonyms: Piperidine, 4-phenyl-1-(4-phenylbutyl)-, (2Z)-2-butenedioate (1:1); Piperidine, 4-phenyl-1-(4-phenylbutyl)-, (Z)-2-butenedioate (1:1); 4-Phenyl-1-(4-phenylbutyl)piperidine maleate; 4-PPBP maleate. Grade: ≥99% by HPLC. CAS No. 201216-39-9. Molecular formula: C21H27N.C4H4O4. Mole weight: 409.52. | |
| 4-P-PDOT | 4-P-PDOT is an antagonist of the melatonin 2 (MT2) receptor (pKi = 8.37) that displays 60-fold selectivity for MT2 over MT1. Synonyms: AH 024; cis-4-phenyl-2-Propionamidotetralin; N-(4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide. Grade: ≥98%. CAS No. 134865-74-0. Molecular formula: C19H21NO. Mole weight: 279.4. | |
| 4-Propyl Aminoantipyrine | A metabolite of aminopyrine. Synonyms: 1,5-dimethyl-2-phenyl-4-propylamino-1,2-dihydro-pyrazol-3-one. Grade: > 95%. CAS No. 101116-41-0. Molecular formula: C14H19N3O. Mole weight: 245.33. | |
| 4-Pyridinethioamide | An derivative of Ethionamide. Ethionamide is an antibiotic used in the treatment of tuberculosis. Uses: Thioisonicotinamide is an impurity of ethionamide (e890420) with tuberculostatic activity. Synonyms: pyridine-4-carbothioamide. Grade: > 95 %. CAS No. 2196-13-6. Molecular formula: C6H6N2S. Mole weight: 138.19. | |
| 4-Pyridoxic acid | A metabolite of Pyridoxine. Pyridoxine is a form of vitamin B6 found commonly in food and used as dietary supplement. It can be used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, problems from isoniazid, and mushroom poisoning. Synonyms: 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxylic acid. Grade: > 95 %. CAS No. 82-82-6. Molecular formula: C8H9NO4. Mole weight: 183.16. | |
| 4-Quinolone-3-carboxamide CB2 ligand | 4-Quinolone-3-carboxamide CB2 ligand is a selective, high-affinity ligand of the CB2 receptor. Synonyms: 4Q3C CB2 Ligand; N-(1-adamantyl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide. Grade: ≥98%. CAS No. 1314230-69-7. Molecular formula: C26H34N2O3. Mole weight: 422.6. | |
| 4-Quinolone-3-carboxamide furan CB2 agonist | 4-Quinolone-3-carboxamide furan CB2 agonist is an agonists of the peripheral cannabinoid (CB) receptor CB2 may have antinociceptive and anti-inflammatory effects, as well as prevent osteoporosis. Synonyms: 4Q3C CB2 Agonist; N-(1-adamantyl)-6-(furan-2-yl)-8-methoxy-4-oxo-1-pentylquinoline-3-carboxamide. Grade: ≥98%. CAS No. 1314230-75-5. Molecular formula: C30H36N2O4. Mole weight: 488.6. | |
| 4-((R)-((R)-2-amino-2-carboxyethyl)sulfinyl)butanoic acid | 4-((R)-((R)-2-amino-2-carboxyethyl)sulfinyl)butanoic acid is one of Cysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: S-Carboxypropyl-L-Cysteine-(S)-Sulfoxide. Molecular formula: C7H13NO5S. Mole weight: 223.25. | |
| 4SC-202 | 4SC-202 is a selective and potent, orallly available inhibitor of histone deacetylases (HDAC) specific for class 1 HDAC isoenzymes, with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. 4SC-202 also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). In addition, 4SC-202 shows a broad anti-proliferative activity towards human cancer cell lines with a mean IC50 of 0.7 μM. Synonyms: 4SC202; 4SC-202; 4SC 202; domatinostat; (E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide. CAS No. 910462-43-0. Molecular formula: C23H21N5O3S. Mole weight: 447.51. | |
| 4SC-202 Tosylate | 4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones.This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, upregulated in many tumor types, are a class of enzymes that deacetylate chromatin histone proteins. Synonyms: 4SC-202; 4SC 202; 4SC202. Grade: 0.98. CAS No. 1186222-89-8. Molecular formula: C30H29N5O6S2. Mole weight: 619.711. | |
| 4SC-203 | 4SC-203 is a multikinase inhibitor with potential antineoplastic activity. Multikinase inhibitor 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs). This may result in the inhibition of angiogenesis and cell proliferation in tumor cells in which these kinases are upregulated. Synonyms: 4SC-203; 4SC 203; 4SC203; SC71710; SC-71710; SC 71710. Grade: 98%. CAS No. 895533-09-2. Molecular formula: C33H38N8O4S. Mole weight: 642.78. | |
| 4SC-207 | 4SC-207 is a novel microtubule inhibitor. It shows strong anti-proliferative activity in a large panel of tumor cell lines with an average GI50 of 11 nM. Synonyms: 4SC207; 4SC-207; 4SC 207. Grade: >98%. CAS No. 871015-11-1. Molecular formula: C19H18N4O3S. Mole weight: 382.44. | |
| 4S-Des-3-chloropyridine Edoxaban Sodium Salt | 4S-Des-3-chloropyridine Edoxaban Sodium Salt is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: Edoxaban Impurity 7 (1S,2R,4S) Sodium Salt; 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid, sodium salt (1:1). Molecular formula: C19H26N5O5SNa. Mole weight: 459.5. | |
| 4(S)-Edoxaban Pyridine N-Oxide | 4(S)-Edoxaban Pyridine N-Oxide is an impurity of Edoxaban. Edoxaban is an anticoagulant medication and a direct factor Xa inhibitor. Synonyms: 5-chloro-2-(2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetamido)pyridine 1-oxide; Edoxaban N-Oxide; Edoxaban Impurity 8; Edoxaban N-Oxide Impurity 2. CAS No. 2803372-49-6. Molecular formula: C24H30ClN7O5S. Mole weight: 564.06. | |
| 4-((S)-((R)-2-amino-2-carboxyethyl)sulfinyl)butanoic acid | 4-((S)-((R)-2-amino-2-carboxyethyl)sulfinyl)butanoic acid is one of Cysteine impurities. It has potential anticancer activity against tumor cell growth. Synonyms: S-Carboxypropyl-L-Cysteine-(R)-Sulfoxide. Molecular formula: C7H13NO5S. Mole weight: 223.25. | |
| 4-Sulfamoylbenzoic acid | Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors. Uses: Carzenide could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors. Synonyms: 4-sulfamoylbenzoic acid. Grade: > 98 %. CAS No. 138-41-0. Molecular formula: C7H7NO4S. Mole weight: 201.20. | |
| 4-Sulfate Aminoantipyrine | A metabolite of aminopyrine. Synonyms: (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-sulfamic acid. Grade: > 95%. CAS No. 1759-26-8. Molecular formula: C11H13N3O4S. Mole weight: 283.31. | |
| 4-Sulfated Lewis X methyl glycoside | 4-Sulfated Lewis X methyl glycoside is an exceptional and indispensable compound, exhibiting tremendous potential in the realm of studying both inflammatory disorders and cancer. This multifaceted compound exerts its functions by competently inhibiting selectin proteins responsible for facilitating intricate cell-cell interactions. This compound plays a pivotal role in impeding cell adhesion and augmenting anti-metastatic actions. Synonyms: Methyl (4-sulfo-b-D-galactopyranosyl)-1-b-4-O-[(a-L-fucopyranosyl)-1-a-3]-2-acetamido-2-deoxy-b-D-glucopyranoside; 4-SO3H-Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-O-Me; Methyl O-6-deoxy-α-L-galactopyranosyl-(1→3)-O-[4-O-sulfo-β-D-galactopyranosyl-(1→4)]-2-(acetylamino)-2-deoxy-β-D-glucopyranoside; Fuc(a1-3)[Gal4S(b1-4)]b-GlcNAc1Me; (2R,3R,4R,5R,6S)-6-(((2R,3S,4R,5R,6R)-5-Acetamido-2-(hydroxymethyl)-6-methoxy-4-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl hydrogen sulfate. CAS No. 386229-72-7. Molecular formula: C21H37NO18S. Mole weight: 623.58. | |
| 4'-Sulphated Lewis X, Methyl Glycoside Sodium Salt | Recently shown to be a good ligand for E- and L-selectins, two calcium-dependent mammalian lectins associated with early steps in the inflammatory response and lymphocyte extravasation into peripheral lymph nodes which makes them good candidates for anti-inflammatory drugs. Synonyms: 4'-SO4-Gal1-b-4[Fuc1-α-3]GlcNAc-b-O-Me; Methyl O-6-deoxy-α-L-galactopyranosyl-(1→3)-O-[4-O-sulfo-β-D-galactopyranosyl-(1→4)]-2-(acetylamino)-2-deoxy-β-D-glucopyranoside sodium salt. Grade: 95%. Molecular formula: C21H36NNaO18S. Mole weight: 645.56. | |
| 4-Tetradecanamidobenzylphosphonic Acid | S32826 is a potent and selective inhibitor of autotaxin. Autotaxin catalyzes the transformation of lyso-phosphatidylcholine in lyso-phosphatidic acid (LPA). S32826 inhibits LPA release from adipocytes (IC50 = 90 nM) and reduces plasma autotaxin activity. Synonyms: 4-Tetradecanamidobenzylphosphonic acid. Grade: ≥98%. CAS No. 1096770-84-1. Molecular formula: C21H36NO4P. Mole weight: 397.5. | |
| 4-Thio-1-acetyl-2,3,5-tri-O-benzoyl-b-L-ribofuranose | 4-Thio-1-acetyl-2,3,5-tri-O-benzoyl-b-L-ribofuranose. | |
| 4'-Thio-2'-deoxycytidine | 4'-Thio-2'-deoxycytidine is a modified nucleoside where the oxygen atom at the 4' position of the ribose sugar is replaced with a sulfur atom, creating a thio group. The 2'-deoxy structure means the nucleoside lacks the hydroxyl group at the 2' position, making it a deoxyribonucleotide, which is commonly used in DNA synthesis. The 4'-thio modification increases the stability of the nucleoside and can improve its resistance to nucleases. This modification can also affect the binding affinity and specificity of the nucleoside in interactions with other nucleic acids or proteins. 4'-Thio-2'-deoxycytidine is often used in DNA-based research, including gene editing, oligonucleotide design, and therapeutic applications, where stability and nuclease resistance are important. Synonyms: 2'-Deoxy-4'-thiocytidine; NSC 764276; 1-(2-Deoxy-4-thio-beta-D-ribofuranosyl)cytosine; 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidin-2(1H)-one. Grade: ≥95%. CAS No. 134111-30-1. Molecular formula: C9H13N3O3S. Mole weight: 243.28. | |
| 4'-Thio-2'-deoxyguanosine | 4'-Thio-2'-deoxyguanosine is a modified nucleoside where a sulfur atom replaces the oxygen atom at the 4' position of the deoxyribose sugar in 2'-deoxyguanosine. This sulfur substitution alters the properties of the nucleoside, potentially increasing its stability or changing its interactions in nucleic acid structures. It can be incorporated into oligonucleotides during DNA synthesis for applications in studying DNA structure, function, and stability, or for creating DNA probes and analogs with altered chemical properties. This modification can also be used to investigate the effects of sulfur substitutions on base pairing and DNA hybridization. Synonyms: 2'-Deoxy-4'-thioguanosine; 2-Amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-1H-purin-6-one. Grade: ≥95%. CAS No. 135656-33-6. Molecular formula: C10H13N5O3S. Mole weight: 283.31. | |
| 4-Thio-2'-deoxythymidine | 4-Thio-2'-deoxythymidine is a highly efficacious antiviral derivative of thymidine prevalent in the compound sector, showcasing remarkable proficiency in curtailing DNA and RNA viruses, encompassing herpesviruses, HIV is and hepatitis B virus. By hampering the research and development of nucleic acids, this compound efficaciously impedes viral replication. Grade: ≥ 98% by HPLC. Molecular formula: C10H14N2O4S. Mole weight: 258.3. | |
| 4-Thio-2'-deoxyuridine | 4-Thio-2'-deoxyuridine is a nucleoside analog, widely employed for the targeted research of viral infections caused by the herpes simplex and varicella-zoster viruses. By effectively impeding the research and development of viral DNA, it manifests its potent antiviral attributes. Notably, due to its unique thio substitution, this compound augments antiviral efficacy while concurrently mitigating any potential cytotoxic effects. Grade: ≥ 98% by HPLC. Molecular formula: C9H12N2O4S. Mole weight: 244.27. | |
| 4-Thio-2'-F-dU Phosphoramidite | 4-Thio-2'-F-dU Phosphoramidite is a chemically modified phosphoramidite in which the oxygen atom at the 4-position of the uracil base is replaced with a sulfur atom, and the ribose sugar is substituted with a fluorine atom at the 2'-position. The 3'-cyanoethyl (CE) phosphoramidite group facilitates its incorporation into oligonucleotides during automated synthesis. This modification enhances the stability and nuclease resistance of the resulting DNA strands and introduces unique structural and chemical properties, such as thiol-reactive functionality. It is widely used in therapeutic oligonucleotide development, molecular biology research, and the study of nucleic acid-protein interactions. Synonyms: 4-Thio-2'-F-dU CEP; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-4-S-(2-cyanoethyl)-2'-deoxy-2'-fluoro-4-thio-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-4-S-(2-cyanoethyl)-2'-deoxy-2'-fluoro-4-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 4-S-(2-cyanoethyl)-2'-F-dU 3'-CE-phosphoramidite. Grade: ≥95%. Molecular formula: C42H49FN5O7PS. Mole weight: 817.91. | |
| 4'-Thioadenosine | 4'-Thioadenosine is a complex nucleoside analogue unveiling promising biomedical applications in studying of cancers. Synonyms: 4'-O-Thiaadenosine; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrothiophene-3,4-diol; NSC 82219. Grade: ≥95%. CAS No. 2500-80-3. Molecular formula: C10H13N5O3S. Mole weight: 283.31. | |
| 4'-Thiocytidine | 4'-Thiocytidine, a compound of utmost importance, finds valuable application within the biomedical sphere, serving as an imperative agent for the exploration and advancement of antiviral therapeutics. Its significance lies in its pivotal contribution to the amalgamation of nucleoside analogues, specifically targeting the remedy of viral afflictions like hepatitis B and C. Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)cytosine; Cytidine, 4'-thio-; Tarac; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidin-2-one. Grade: ≥95%. CAS No. 93080-09-2. Molecular formula: C9H13N3O4S. Mole weight: 259.28. | |
| 4-Thio-dT-CE Phosphoramidite | 4-Thio-dT-CE Phosphoramidite, a pivotal reagent, is extensively employed in the oligonucleotide synthesis process for combating viral infections, including but not limited to HIV and hepatitis C. Moreover, it is integral to the fabrication of antisense oligos that hold immense promise in the domain of targeted gene therapy. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-4-(2-cyanoethylthio)-Thymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 1290537-73-3. Molecular formula: C43H52N5O7PS. Mole weight: 813.95. | |
| 4-THIO-DU CEP | 4-THIO-DU CEP is a potent compound used to research urinary tract infections caused by bacteria. It acts by inhibiting the enzymes responsible for bacterial cell wall research and development, effectively stopping their growth. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-4-(2-cyanoethylthio)-Uridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 4-Thio-dU-CE Phosphoramidite. Grade: 95%. CAS No. 144303-74-2. Molecular formula: C42H50N5O7PS. Mole weight: 799.93. | |
| 4-Thio-ethyl-UTP | 4-Thio-ethyl-UTP, a compound extensively utilized in biomedical research, particularly in the field of RNA splicing and editing, is an immensely versatile alternative substrate to UTP, especially when investigating the function of RNA editing enzymes. Its exclusive selectivity for specific RNA sequences further enhances its usefulness, rendering it an essential tool for studying cancer and genetic disorders. Synonyms: 4-Thio-ethyl-uridine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C11H19N2O14P3S (free acid). Mole weight: 528.26 (free acid). | |
| 4'-Thioguanosine | 4'-Thioguanosine, a highly regarded compound, plays a pivotal role in the research of diverse conditions, encompassing viral infections, autoimmune disorders and specific cancer forms. Employing a unique mechanism, 4'-Thioguanosine disrupts viral replication processes while concurrently regulating immune responses, culminating in a notable reduction in viral load and corresponding inflammation levels. Synonyms: 4'-O-Thiaguanosine; Guanosine, 4'-thio-; 9-(4-Thio-beta-D-ribofuranosyl)guanine; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-1H-purin-6-one. Grade: 95%. CAS No. 74249-68-6. Molecular formula: C10H13N5O4S. Mole weight: 299.31. | |
| 4-Thio-i-butyl-UTP | 4-Thio-i-butyl-UTP, a nucleotide analogue utilized in biomedical studies, offers a unique opportunity to investigate RNA structure and function. With a wide range of applications, it plays a critical role in researching RNA-dependent processes in enzymatic assay systems. Moreover, recent studies have unveiled its antiviral properties, indicating its potential as a powerful drug development candidate for targeting specific viral infections. Synonyms: 4-Thio-iso-butyl-uridine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C13H23N2O14P3S (free acid). Mole weight: 556.31 (free acid). | |
| 4'-Thioinosine | 4'-Thioinosine, a purine nucleoside analog utilized within the biomedical industry to study adenosine transport inhibition's effects on tumor growth. Its potential as a treatment for autoimmune diseases, like rheumatoid arthritis, has been established via the suppression of inflammatory pathways. Synonyms: NSC 90420; 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-1H-purin-6-one; Inosine, 4'-thio-. Grade: ≥95%. CAS No. 58004-19-6. Molecular formula: C10H12N4O4S. Mole weight: 284.29. | |
| 4-Thio-i-propyl-UTP | 4-Thio-i-propyl-UTP, a biochemical compound used in biomedical research, is known for its efficacy in the evaluation of P2Y receptor function. Scientists heavily rely on it to look at signaling pathways implicated in diseases affecting multiple organ systems such as cancer, diabetes, and neurodegenerative disorders. This substrate has the power to activate adenylate cyclase through P2Y receptor-mediated processes. Studying these receptors using this compound has been shown to shed light on pathogenic mechanisms. Its use is well-established across the scientific community, both in vitro and in vivo. Synonyms: 4-Thio-iso-propyl-uridine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C12H21N2O14P3S (free acid). Mole weight: 542.27 (free acid). | |
| 4-Thio-methyl-UTP | 4-Thio-methyl-UTP is an intricate compound commonly employed in the realm of investigative research and diagnostics. This distinctive altered nucleotide analog effortlessly integrates into RNA throughout transcription, bestowing itself as a paramount instrument for scrutinizing DNA research and development and RNA alterations. Notably, it showcases exceptional utility in delving into the significant role that precise nucleotides play in influencing the intricate facets of RNA's structural composition and functional behavior. Synonyms: 4-Thio-methyl-uridine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H17N2O14P3S (free acid). Mole weight: 514.23 (free acid). | |
| 4-Thiomorpholineacetic acid, 3-carboxy-5-oxo-, (3R)- | An impurity of Carbocisteine, which is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Synonyms: (R)-4-(carboxymethyl)-5-oxothiomorpholine-3-carboxylic acid. CAS No. 1601460-92-7. Molecular formula: C7H9NO5S. Mole weight: 219.21. | |
| 4-Thio-n-propyl-UTP | 4-Thio-n-propyl-UTP is a fundamental biosynthetic molecule,finding multifarious applications in examining the intricate dynamics of RNA research and development and modification. Its existence is a profound comprehension of intricate cellular processes concerning gene expression and regulation can be attained. Additionally, owing to its remarkable attributes, 4-Thio-n-propyl-UTP assumes a critical role in unraveling the nuances of RNA metabolism and development. Synonyms: 4-Thio-n-propyl-uridine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C12H21N2O14P3S (free acid). Mole weight: 542.29 (free acid). | |
| 4-Thiothymidine | 4-Thiothymidine, a nucleoside analogue, exhibits potent antiviral activity by inhibiting DNA replication. This sulfur-containing compound specifically targets thymidine kinase, an enzyme essential for DNA synthesis, which offers promising applications in antiviral therapies. Notably, its efficacy has been observed against HIV and hepatitis B, making it a valuable research tool in biomedical studies. The intricate biochemistry of 4-Thiothymidine highlights its potential for further investigations and development of novel therapeutic agents. Synonyms: 4-Thio-D-thymidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one; 4-Thiodeoxythymidine; 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one; 3,4-Dihydro-5-methyl-1-(2-deoxy-β-D-ribofuranosyl)-4-thioxopyrimidin-2(1H)-one. Grade: ≥98% by HPLC. CAS No. 7236-57-9. Molecular formula: C10H14N2O4S. Mole weight: 258.29. | |
| 4'-Thiothymidine | 4'-Thiothymidine is a modified version of thymidine, where the 4' oxygen of the deoxyribose sugar is replaced by a sulfur atom. This modification introduces unique chemical properties, such as increased stability or altered reactivity, which can be useful in the synthesis of specialized nucleic acid analogs or for studying nucleic acid interactions. Thionucleosides like 4'-thiothymidine may also be used in antiviral or anticancer research due to their potential for incorporating into DNA while disrupting normal cellular processes. Synonyms: 4'-Thio-2'-deoxy-5-methyluridine; 4'-Thio thymidine; 2'-Deoxy-4'-thiothymidine; 1-(2-Deoxy-4-thiopentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-5-methyl-pyrimidine-2,4-dione; 4'-Thio-2'-deoxythymidine. Grade: ≥95%. CAS No. 134111-33-4. Molecular formula: C10H14N2O4S. Mole weight: 258.30. | |
| 4-Thiothymidine-5'-Triphosphate | 4-Thiothymidine-5'-Triphosphate is a key component in biomedical research for studying DNA research and development and replication. It is a modified nucleotide that incorporates into DNA during replication, acting as an artificial base analog. This compound is used to investigate various processes such as DNA repair mechanisms, mutagenesis, antiviral drug development. Synonyms: 4-Thio-dTTP. Grade: ≥90% by AX-HPLC. Molecular formula: C10H17N2O13P3S. Mole weight: 498.24. | |
| 4-Thiothymidine-5'-triphosphate lithium salt | 4-Thiothymidine-5'-triphosphate lithium salt is a crucial compound exhibiting significant potential as an antiviral compound due to its ability to inhibit viral replication by blocking DNA polymerase. This compound is mainly utilized in the development of therapeutic strategies to combat viral infections, including HIV. Its unique properties make it an invaluable tool in the study and research of various viral diseases. Synonyms: Lithium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate. Grade: ≥ 95%. CAS No. 20188-78-7. Molecular formula: C10H17N2O13P3S·xLi. Mole weight: 498.23 (free acid). | |
| 4-Thio-UDP | 4-Thio-UDP, in the realm of compound industry, standing as a prominent biochemical compound of significant usage. Exhibiting itself as a substrate for multifarious enzymes governing intricate cellular processes, it has garnered attention due to its potential therapeutic implications concerning nucleotide metabolism and signaling pathways. Its paramountcy in research pertaining to cancer, neurodegenerative disorders and immune system impairments remains undeniable. Synonyms: 4-Thio-uridine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N2O11P2S (free acid). Mole weight: 420.22 (free acid). | |
| 4-Thio-UMP | 4-Thio-UMP is a modified nucleoside used to treat various types of cancer and viral infections. It works by selectively inhibiting DNA and RNA synthesis in cancer cells or virus-infected cells, leading to their death. Its anti-tumor activity has been demonstrated in preclinical models of colon, breast, and lung cancer. Additionally, 4-Thio-UMP has also been shown to have antiviral effects against several RNA viruses such as influenza A, hepatitis C, and Zika virus. Synonyms: 4-Thio-uridine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H13N2O9PS (free acid). Mole weight: 340.24 (free acid). | |
| 4-Thiouridine | Nucleotide analogue is essential to cell growth in certain bacterial species, which is also able to chelate with certain metal ions, and in tRNA. It can act as a built-in antiphotomutagenic agent protecting Escherichia coli cells against mutagenesis. Uses: Affinity labels. Synonyms: Uridine, 4-thio-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one; 1-beta-D-ribofuranosyl-4-thiouracil; 1-(β-D-Ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone; 4-Thio Uridine. Grade: ≥95%. CAS No. 13957-31-8. Molecular formula: C9H12N2O5S. Mole weight: 260.27. | |
| 4-Thio-uridine | 4-Thio-uridine is a prominent biomedical compound renowned for its formidable anti-viral capabilities. By impeding viral replication while concurrently attenuating inflammation, 4-Thio-uridine plays an important role in the research of these deleterious conditions. Grade: ≥ 98% by HPLC. Molecular formula: C9H12N2O5S. Mole weight: 260.27. | |
| 4'-Thiouridine | 4'-Thiouridine is a nucleoside analogue employed in the biomedical sector for investigative endeavors, predominantly within nucleic acid examinations. Its assimilation into RNA molecules facilitates the exploration of RNA's intricate framework and its inherent functionalities. Research elucidating RNA editing mechanisms and the ramifications of nucleoside modifications on genetic expression finds immense utility in this compound. Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)uracil; Uridine, 4'-thio-; 4'-O-Thiauridine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 6741-73-7. Molecular formula: C9H12N2O5S. Mole weight: 260.27. | |
| 4-Thiouridine 2',3',5'-Triacetate | 4-Thiouridine 2',3',5'-Triacetate is used as an intermediate in the synthesis of 4-Thiouridine, an nucleotide analogue essential for cell growth in certain bacterial species. Synonyms: 4-Thiouridine Triacetate. CAS No. 55003-25-3. Molecular formula: C15H18N2O8S. Mole weight: 386.38. | |
| 4-Thiouridine-5'-triphosphate sodium salt | 4-Thiouridine-5'-triphosphate sodium salt, a nucleotide analogue extensively employed as a substrate for RNA polymerases, has evoked a plethora of diverse inquiries to investigate the intricate mechanisms of RNA editing and splicing. Significantly, its unique attributes permit specific positioning and labeling of RNA strands, attributing to unparalleled detectability, purification, and quantification. Synonyms: 4-Thio-utp. Molecular formula: C9H15N2O14P3S·4Na. Mole weight: 592.17. | |
| 4-Thiouridine-5'-triphosphate (triethylammonium salt) | An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Synonyms: 4-thiouridine triphosphate (triethylammonium salt form). Grade: 95%. Molecular formula: C9H15N2O14P3S.C6H15N. Mole weight: 500.207 (free acid). | |
| 4-Thio-UTP | 4-Thio-UTP is an agonist of P2Y2 and P2Y4 receptors that can influence on transcription process to terminate chain extension. Synonyms: 4-Thiouridine-5'-Triphosphate; Thio UTP. Grade: ≥ 95% by HPLC. CAS No. 31556-28-2. Molecular formula: C9H15N2O14P3S (free acid). Mole weight: 500.20 (free acid). | |
| 4-Toluoyl 2,3-di-O-benzoyl-4,6-O-benzylidene-b-D-thioglucopyranoside | 4-Toluoyl 2,3-di-O-benzoyl-4,6-O-benzylidene-b-D-thioglucopyranoside, an indispensable compound with extensive applications in the field of biomedicine, holds immense scientific value. Its remarkable functionality as a glucokinase enzyme activator offers promising prospects for the treatment of diabetes. Moreover, the inhibitory effects demonstrated against pancreatic α-amylase and α-glucosidase make it a compelling contender for the advancement of anti-diabetic pharmaceuticals. Molecular formula: C35H30O8S. Mole weight: 610.68. | |
| 4-Toluoyl 2,3-di-O-benzyl-4,6-O-benzylidene-b-D-thioglucopyranoside | 4-Toluoyl 2,3-di-O-benzyl-4,6-O-benzylidene-b-D-thioglucopyranoside, an indispensable compound in the field of biomedicine, offers tremendous versatility for diverse applications. Acting as a vital reagent, it facilitates the synthesis of prospective medications, envisaged to combat various ailments such as cancer, diabetes, and inflammation. Molecular formula: C35H34O6S. Mole weight: 582.71. | |
| 4-Toluoyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-(9-fluorenylmethoxycarbonyl)-a-D-thiomannopyranoside | 4-Toluoyl 2-O-benzoyl-3,4-di-O-benzyl-6-O-(9-fluorenylmethoxycarbonyl)-a-D-thiomannopyranoside - a multifaceted chemical compound that has exhibited promising therapeutic properties in numerous research studies spanning several medical fields. Its antiviral and anticancer properties have stood the test of time, while its potential in treating Alzheimer's disease and improving inflammatory conditions continues to be a hot topic in the pharmaceutical world. Molecular formula: C50H44O9S. Mole weight: 820.95. | |
| 4-Toluoyl 2-O-benzyl-4,6-O-benzylidene-3-O-p-methoxybenzyl-a-D-thiomannopyranoside | 4-Toluoyl 2-O-benzyl-4,6-O-benzylidene-3-O-p-methoxybenzyl-a-D-thiomannopyranoside is an esteemed and valuable compound, manifesting potent anti-inflammatory, antioxidant and anti-cancer properties. Through the skillful inhibition of disease-associated enzymes and pathways, it plays an important role in research of a diverse range of maladies. Molecular formula: C35H36O6S. Mole weight: 584.72. | |
| 4-Toluoyl-2-O-benzyl-4,6-O-benzylidene-a-D-thiomannopyranoside | 4-Toluoyl-2-O-benzyl-4,6-O-benzylidene-a-D-thiomannopyranoside is a remarkable compound widely employed in the biomedical sector, exhibiting extraordinary antiviral prowess. With a proven ability to impede viral replication, it serves as a propitious candidate for combatting diverse viral afflictions. Synonyms: S-((4aR,6R,7S,8S,8aS)-7-(benzyloxy)-8-hydroxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-6-yl) 4-methylbenzothioate. CAS No. 950602-62-7. Molecular formula: C28H28O6S. Mole weight: 492.6. | |
| 4-Toluyl 3,4-di-O-acetyl-2-O-benzyl-a-L-thiofucopyranoside | 4-Toluyl 3,4-di-O-acetyl-2-O-benzyl-a-L-thiofucopyranoside is a multifunctional and intriguing compound, presenting remarkable thiofucoside properties. This compound uniquely boasts acetyl and benzyl substituents, fostering novel perspectives for drug development. Synonyms: 4-Methylphenyl 3,4-di-O-acetyl-2-O-benzyl-1-thio-b-Lfucopyranoside. CAS No. 1632312-32-3. Molecular formula: C25H28O7S. Mole weight: 472.6. | |
| 4-Tolylboronic acid D7 | 4-Tolylboronic acid D7. Synonyms: 4-Methylphenylboronic acid-d7. Grade: 95% by HPLC; 98% atom D. Molecular formula: C7H2D7BO2. Mole weight: 143.00. | |
| 4"-trans-Hydroxy Cilostazol | 4"-trans-Hydroxy Cilostazol is a metabolite of Cilostazol. Synonyms: trans-3,4-Dihydro-6-[4-[1-(4-hydroxycyclohexyl)-1H-tetrazol-5-yl]butoxy]-2(1H)-quinolinone; OPC 13213. Grade: > 95%. CAS No. 87153-04-6. Molecular formula: C20H27N5O3. Mole weight: 385.46. | |
| 4-Triazolyl-5-methyl-dU CEP | 4-Triazolyl-5-methyl-dU CEP is a crucial compound utilized in the field of biomedicine. With its unique structure and properties, this chemical plays a vital role in the synthesis of pharmaceutical drugs targeting various diseases such as cancer, viral infections, and neurological disorders. Molecular formula: C42H50N7O7P. Mole weight: 795.88. | |
| 4-Triazolyl-dU-CEP | 4-Triazolyl-dU-CEP is a notable and significant compound, exhibiting paramount importance in the research and development of nucleoside analogs. Specifically, this compound serves as a pivotal intermediate in the progression of antiviral medications, specifically nucleotide polymerase inhibitors. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-4-Triazolyl-Uridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; O4-Triazolyl-dU-CE Phosphoramidite. Grade: 95%. CAS No. 109389-31-3. Molecular formula: C41H48N7O7P. Mole weight: 781.84. | |
| 4'-(Tribromomethyl)-[1,1'-biphenyl]-2-carboxylic Acid | 4'-(Tribromomethyl)-[1,1'-biphenyl]-2-carboxylic Acid is one of telmisartan impurities. Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension. Molecular formula: C14H9Br3O2. Mole weight: 448.93. | |
| 4-(Trifluoromethoxy)phenyl Isothiocyanate | 4-(Trifluoromethoxy)phenyl Isothiocyanate is used as a reagent in the synthesis of thiourea and thioether derivatives of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: Benzene, 1-isothiocyanato-4-(trifluoromethoxy)-; Isothiocyanic Acid 4-(Trifluoromethoxy)phenyl Ester; 1-Isothiocyanato-4-trifluoromethoxybenzene; 4-Isothiocyanatophenyl trifluoromethyl ether. Grade: ≥95%. CAS No. 64285-95-6. Molecular formula: C8H4F3NOS. Mole weight: 219.18. | |
| 4-(Trifluoromethyl)aniline | 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis. Synonyms: 4-(trifluoromethyl)aniline. Grade: 98 %. CAS No. 455-14-1. Molecular formula: C7H6F3N. Mole weight: 161.12. | |
| 4-(Trifluoromethyl)phenol | 4-Hydroxybenzotrifluoride can be used to synthesize P2Y1 antagonists and antithrombotic agents. Uses: P-trifluoromethylphenyl is used in the synthesis of p2y1 antagonists and antithrombotic agents. also, used in the synthesis of potent myeloid cell leukemia inhibitors. Synonyms: p-Cresol, α,α,α-trifluoro-; 4-Hydroxybenzotrifluoride; NSC 88303; p-Hydroxybenzotrifluoride; p-Trifluoromethylphenol; α,α,α-Trifluoro-4-cresol; α,α,α-Trifluoro-p-cresol. Grade: >95%. CAS No. 402-45-9. Molecular formula: C7H5F3O. Mole weight: 162.11. | |
| 4-Trifluoromethylumbelliferyl a-D-N-acetylneuraminic acid | 4-Trifluoromethylumbelliferyl α-D-N-acetylneuraminic acid is a highly intricate and multifaceted biomedical innovation, standing as a vital tool employed for the meticulous detection and comprehensive analysis of sialic acids in diverse pharmaceutical compositions and pathological states. Exhibiting remarkable fluorescence, this remarkable substrate enables efficacious assays, empowering researchers to delineate and quantify concentrations of sialic acid with unparalleled precision. Synonyms: CF3MU-Neu5Ac; α-Neuraminic acid, N-acetyl-2-O-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; N-Acetyl-2-O-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-α-neuraminic acid; (2S,4S,5R,6R)-5-acetamido-4-hydroxy-2-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)oxy)-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid. Grade: ≥95%. CAS No. 195210-03-8. Molecular formula: C21H22F3NO11. Mole weight: 521.39. | |
| 4-Trifluoromethylumbelliferyl α-D-N-Acetylneuraminate Methyl Ester | An intermediate for the synthesis of a fluorogenic substrate used to measure sialidase activity. Synonyms: N-Acetyl-2-O-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-α-neuraminic Acid Methyl Ester; α-Neuraminic acid, N-acetyl-2-O-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-, methyl ester; Methyl (2S,4S,5R,6R)-5-acetamido-4-hydroxy-2-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)oxy)-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylate. Molecular formula: C22H24F3NO11. Mole weight: 535.42. | |
| 4-Trifluoromethylumbelliferyl-α-D-N-acetylneuraminic Acid Sodium Salt | Used as a substrate in a fluorometric detection of poorly expressed natural and recombinant sialidases. Synonyms: CF3MU-Neu5Ac Sodium Salt; N-Acetyl-2-O-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-α-neuraminic acid sodium salt; (2S,4S,5R,6R)-5-acetamido-4-hydroxy-2-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)oxy)-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylate sodium salt. Grade: 95%. Molecular formula: C21H21F3NNaO11. Mole weight: 543.38. | |
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