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5'-Amino-2',5'-dideoxyuridine
5'-Amino-2',5'-dideoxyuridine is an imperative nucleoside analogue of significant relevance in the biomedical sector is effectively harnessed for addressing the ubiquitous viral diseases encompassing herpes and HIV. Distinguished by its remarkable characteristic, this compound effectively obstructs the progression of viral DNA synthesis through its adeptness at terminating replication chains. Moreover, its commendable antiviral attributes render it a promising candidate in the realm of therapeutic agent advancement, effectively countering the virulent onslaught of diverse viral infections. Synonyms: Uridine, 5'-amino-2',5'-dideoxy-; 5'-NH2-2'-dU; 1-[(2R,4S,5R)-5-(aminomethyl)-4-hydroxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 35959-38-7. Molecular formula: C9H13N3O4. Mole weight: 227.22.
5-Amino-2-chlorobenzotrifluoride N-Chloroacetyl N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, which is a derivative of Regorafenib and a compound that inhibits PDGFR tyrosine kinase with IC50 = 83 nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2R,3R,4S,5S,6S)-2-((4-Chloro-3-(trifluoromethyl)phenyl)(chlorocarbonyl)amino)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C21H20Cl2F3NO10. Mole weight: 574.29.
5-Amino-2-chlorobenzotrifluoride N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, which is a derivative of Regorafenib and a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2R,3R,4S,5S,6S)-2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C20H21ClF3NO9. Mole weight: 511.83.
5-Amino-2-cyanobenzotrifluoride
An impurity of Bicalutamide. Bicalutamide is a non-steroidal antiandrogen used primarily in the treatment of prostate cancer. It works by competitively inhibiting the androgen receptor (AR), blocking the effects of testosterone and dihydrotestosterone (DHT) on cancer cell growth. Synonyms: Bicalutamide Impurity D; Bicalutamide EP Impurity D; 4-Amino-α,α,α-trifluoro-o-tolunitrile; 2-Trifluoromethyl-4-aminobenzonitrile; 4-Cyano-3-(trifluoromethyl)aniline; 4-Amino-2-trifluoromethylbenzonitrile; 4-Cyano-3-(trifluoromethyl)aniline; Bicalutamide aminobenzonitrile; 2-Cyano-5-aminobenzotrifluoride. Grade: >95%. CAS No. 654-70-6. Molecular formula: C8H5F3N2. Mole weight: 186.14.
5-Amino-2'-deoxyuridine hydrochloride, an essential component within the biomedical sector, serves as a pivotal precursor for the synthesis of antiviral agents like AZT (zidovudine) - a renowned therapeutic employed in combating the HIV/AIDS epidemic. Noteworthy is its hydrochloride form, augmenting not only solubility but also stability, thereby facilitating the formulation of efficacious medications. Synonyms: 5-Amino-2'-deoxyuridine HCl; 5-Amino-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione hydrochloride; 5-Amino-dU hydrochloride. Grade: ≥95%. CAS No. 73446-40-9. Molecular formula: C9H14ClN3O5. Mole weight: 279.68.
5-Amino-2'-O-methyluridine hydrochloride
5-Amino-2'-O-methyluridine hydrochloride is a critical bioactive component harnessed in biomedical research, manifesting formidable antiviral attributes. Its application encompasses the realm of pharmaceuticals, wherein it contributes to the development of therapeutic compounds tailored to combat viral onslaughts, such as herpes simplex, cytomegalovirus and varicella-zoster virus. Grade: ≥95%. Molecular formula: C10H16ClN3O6. Mole weight: 309.70.
5-Amino-3-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide is a remarkable bioactive compound of paramount significance, harnessed for the research of a plethora of certain malignancies, notably lung and breast carcinomas by impeding oncogenic signaling cascades and curtailing neoplastic cell proliferation. Synonyms: 5-amino-N-(2,6-difluorophenyl)-3-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide; 1H-1,2,4-Triazole-1-carbothioamide, 5-amino-3-[[4-(aminosulfonyl)phenyl]amino]-N-(2,6-difluorophenyl)-. Grade: ≥95%. CAS No. 443798-47-8. Molecular formula: C15H13F2N7O2S2. Mole weight: 425.44.
5-Amino-3-(4-hydroxy-5-(hydroxymethy)tetrahydrofuran-2-yl)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one is an immensely potent compound employed in the research of diverse ailments. It proffers remarkable efficaciousness in research of combatting select malignancies, viral pathologies as well as autoimmunity-related maladies. CAS No. 1229413-99-3. Molecular formula: C9H12N6O4. Mole weight: 268.23.
5-amino-3-((4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one is an imperative pharmaceutical compound, exhibiting remarkable applications in research of diverse ailments encompassing viral infections and cancer. Synonyms: (R)-2-(((R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-hydroxypropan-2-yl)oxy)-2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl benzoate. CAS No. 1229414-16-7. Molecular formula: C9H12N6O4. Mole weight: 268.23.
5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione is an important ingredients in some antiviral agents, exhibitting great efficacy in combatting enigmatic RNA virus-inflicted maladies. 5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione unequivocally impeding virulence dissemination and the perpetual replication, widely applied to research of influenza, hepatitis C, and HIV. Grade: ≥ 97%. CAS No. 122970-40-5. Molecular formula: C10H12N4O6S. Mole weight: 316.29.
5-Amino-3-O(-D-xylopyranosyl)-D-threo-pentano-1,5-lactam is a vital compound extensively used in the biomedicine industry. This product plays a crucial role in the development of therapies for various diseases. Its unique structure allows it to target specific cellular pathways, making it a potential treatment for multiple drug-resistant bacterial infections. Additionally, this compound shows promising results in inhibiting the growth and proliferation of certain cancer cell lines. Synonyms: (3S,4R)-3-Hydroxy-4-(b-D-xylopyranosyloxy)-2-piperidinone. CAS No. 284045-95-0. Molecular formula: C10H17NO7. Mole weight: 263.24.
An impurity of Lenalidomide, a medication used for the treatment of myelodysplastic syndrome (MDS), multiple myeloma, and mantle cell lymphoma (MCL). Synonyms: 5-Amino-4-(4-amino-1-oxoisoindolin-2-yl)-5-oxopentanoic acid. CAS No. 2197414-57-4. Molecular formula: C13H15N3O4. Mole weight: 277.28.
5-Amino-4-chloropyridazin-3(2H)-one
The metabolite in soil and sugar beets of Chloridazon. Synonyms: 4-amino-5-chloro-1H-pyridazin-6-one; 4-amino-5-chloro-1H-pyridazin-6-one. Grade: > 95 %. CAS No. 6339-19-1. Molecular formula: C4H4ClN3O. Mole weight: 145.55.
5-Amino-4-D-ribitylaminouracil Dihydrochloride-13C3 is the unlabeled form of 5-Amino-4-D-ribitylaminouracil Dihydrochloride, which is an intermediate in the synthesis of Lumazine fluorophore. Synonyms: 5-Amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione Dihydrochloride-13C5; 4-(1'-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine Dihydrochloride-13C5; 4-(Ribitylamino)-5-aminouracil-13C5; 4-Ribitylamino-5-amino-2,6-dihydroxypyrimidine Dihydrochloride-13C5; 5-Amino-6-[(D-ribo-2,3,4,5-tetrahydroxypentyl)amino]uracil Dihydrochloride-13C5; 1-[(5-Amino-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinyl)amino]-1-deoxy-D-ribitol Dihydrochloride-13C5. Molecular formula: C6[13C]3H16N4O6 2HCl. Mole weight: 279.22.
5-Amino-4-imidazolecarboxamide Hydrochloride
5-Amino-4-imidazolecarboxamide hydrochloride is the hydrochloride salt of 5-Amino-4-imidazolecarboxamide, a metabolite of Temozolomide. It is also an impurity in the synthesis of Dacarbazine. Synonyms: 4-amino-1H-imidazole-5-carboxamide; hydrochloride; 4-amino-1H-imidazole-5-carboxamide; hydrochloride. Grade: > 95 %. CAS No. 72-40-2. Molecular formula: C4H7ClN4O. Mole weight: 162.58.
5-Amino-5-deoxy-1,2-O-isopropylidene-6-O-trityl-α-D-galactofuranose is a synthetic carbohydrate intermediate that exhibits immense potential in the production of glyco-conjugates by providing significant advantages in terms of chemical stability and intramolecular cation binding. This complex compound is widely used in the synthesis of Cluster A glycopeptide epitopes, including trimeric structures, which can be utilized as potential vaccine candidates against the notorious bacterial pathogen, Staphylococcus aureus. Synonyms: 5-Amino-5-deoxy-1,2-O-(1-methylethylidene)-6-O-(triphenylmethyl)-α-D-galactofuranose. CAS No. 109681-00-7. Molecular formula: C28H31NO5. Mole weight: 461.55.
5'-Amino-5'-deoxy-2',3'-O-(1-methylethylidene)-adenosine, an exceptionally potent nucleoside analogue, exhibits remarkable antiviral characteristics. Its application in the biomedical sector revolves around combatting viral infections, primarily those necessitating adenosine for replication. An impressive attribute of this substance lies in its ability to impede viral replication by derailing the intricate viral RNA synthesis pathway, rendering it highly efficacious against an extensive spectrum of viral ailments. Synonyms: 9-[(3aR,4R,6R,6aR)-6-(aminomethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-amine; Adenosine, 5'-amino-5'-deoxy-2',3'-O-(1-methylethylidene)-; 5'-Amino-5'-deoxy-2',3'-O-isopropylidineadenosine. Grade: 98%. CAS No. 21950-36-7. Molecular formula: C13H18N6O3. Mole weight: 306.32.
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine
5'-Amino-5'-deoxy-2'-O-methyl-5-methyluridine, a biomedical agent employed for the therapeutic management of viral ailments including hepatitis C, showcases remarkable antiviral efficacy a result of its capacity to impede viral replication. Its idiosyncratic chemical constitution enables interference with viral RNA synthesis, effectively arresting the advancement of the infection. Synonyms: 5,2'-O-Dimethyl-5'-amino-5'-deoxyuridine; Uridine, 5'-amino-5'-deoxy-5-methyl-2'-O-methyl-; 1-((2R,3R,4R,5R)-5-Aminomethyl-4-hydroxy-3-methoxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 251296-69-2. Molecular formula: C11H17N3O5. Mole weight: 271.27.
5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite, a compound of utmost importance in the biomedical sector, serves as a pivotal entity for crafting modified oligonucleotides. Leveraging its inherent amino and thymidine elements, this phosphoramidite contributes significantly to the advancement of nucleic acid-centered therapeutics, diagnostics, and gene expression investigations. Synonyms: 5'-monomethoxytritylamino-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-Amino-dT-CE Phosphoramidite. CAS No. 194034-71-4. Molecular formula: C39H48N5O6P. Mole weight: 713.81.
5'-Amino-5'-deoxyadenosine
It is an adenosine kinase inhibitor. Synonyms: 5'-Amino-5'-deoxy-D-adenosine; 5'-NH2-Ado; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(aminomethyl)tetrahydrofuran-3,4-diol; NSC 238990; 5'-Deoxy-5'-aminoadenosine. Grade: ≥95%. CAS No. 14365-44-7. Molecular formula: C10H14N6O3. Mole weight: 266.26.
5'-Amino-5'-deoxyguanosine
5'-Amino-5'-deoxyguanosine is a nucleoside analog used in biomedical research. It can be incorporated into oligonucleotides and DNA to study the effects of modified bases on genome stability and function. Additionally, this compound has shown promising anticancer activity through its ability to disrupt DNA replication and induce apoptosis in cancer cells. Synonyms: Guanosine, 5'-amino-5'-deoxy-; 5'-Amino-5'-deoxyguanosine. Grade: 97%. CAS No. 4099-84-7. Molecular formula: C10H14N6O4. Mole weight: 282.26.
5'-Amino-5'-deoxythymidine
It is used in the methods and compositions for treatment of anti-angiogenic resistant cancer. Synonyms: NSC 169339; 1-((2R,4S,5R)-5-(Aminomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Addot; 5'-Amino-2',5'-dideoxythymidine; 5'-deoxy-5'-aminothymidine. Grade: ≥95%. CAS No. 25152-20-9. Molecular formula: C10H15N3O4. Mole weight: 241.24.
5-Aminoallyl-2'-deoxycytidine-5'-Triphosphate
5-Aminoallyl-2'-deoxycytidine-5'-Triphosphate is a vital recompound used in the biomedical industry for enzymatic labeling, detection and analysis of nucleic acids. It can be incorporated during DNA amplification or renhancement processes to introduce aminoallyl moieties. This modified nucleotide triphosphate enables the attachment of fluorescent dyes or functional groups allowing researchers to study gene expression, protein-DNA interactions and other related applications. Synonyms: 5-AA-dCTP; 5-(3-Amino-1-propenyl)-2'-deoxycytidine 5'-triphosphoric acid. Grade: ≥90% by AX-HPLC. Molecular formula: C12H21N4O13P3. Mole weight: 522.00.
5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt-100mM aqueous solution is a vital reagent in the biomedical industry. This product is commonly used for labeling DNA or RNA during synthesis. It is also an essential tool for detecting mutations and gene expressions, allowing for further research in diseases such as cancer, dementia, and HIV. Synonyms: 5-(3-Aminoallyl)-2'-deoxycytidine-5'-triphosphate, lithium salt; 5-AA-dCTP. Molecular formula: C12H17N4O13P3·4Li. Mole weight: 545.97.
5-Aminoallyl-2'-deoxyuridine
5-Aminoallyl-2'-deoxyuridine is a highly prized compound, finding its extensive utility across diverse applications particularly in the realms of molecular biology and bioconjugation studies. The compound assumes a pivotal position in DNA labeling, amplification techniques and hybridization to facilitate the progress of targeted therapeutics, diagnostic assays and innovative drug delivery systems. CAS No. 87980-17-4. Molecular formula: C12H18N4O4. Mole weight: 282.30.
5-Aminoallyl-2'-deoxyuridine-5'-Triphosphate
5-Aminoallyl-2'-deoxyuridine-5'-Triphosphate is a nucleoside triphosphate analog, intercalating into DNA through polymerase chain reaction (PCR). Its pervasive application encompasses DNA labeling and crosslinking, facilitating research on gene expression, genetic aberrations and epigenetic phenomena. Synonyms: 5-AA-dUTP; 5-(3-Amino-1-propenyl)-2'-deoxyuridine 5'-triphosphoric acid. Grade: ≥95% by AX-HPLC. Molecular formula: C12H20N3O14P3. Mole weight: 523.20.
5-Aminoallyl-2'-deoxyuridine 5'-triphosphate, labeled with 5/6-TAMRA
5-Aminoallyl-2'-deoxyuridine 5'-triphosphate, labeled with 5/6-TAMRA is a vital tool in the biomedical industry for DNA modification. This product finds application in fluorescent labeling of nucleotides during PCR or DNA sequencing processes. It allows for accurate detection and visualization of DNA sequences, aiding in disease diagnosis, drug discovery, and genetic research. Synonyms: (((2R,3S,5R)-5-(5-((E)-3-(3',6'-bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamido)prop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid. Grade: 95%. CAS No. 151345-35-6. Molecular formula: C37H40N5O18P3. Mole weight: 935.66 (free acid).
5-Aminoallylcytidine 5'-triphosphate lithium salt-100mM aqueous solution is a biochemical reagent widely used in the biomedical industry. It serves as a substrate for the enzymatic labeling of nucleic acids, enabling the introduction of aminoallyl-modified cytidine residues. This modified nucleotide can be utilized in various downstream applications, including RNA labeling, microarray analysis, and nucleic acid detection assays. It plays a crucial role in research related to drug development, molecular diagnostics, and understanding disease mechanisms. Synonyms: 5-AA-CTP. Grade: 90%. Molecular formula: C12H21N4O14P3·xLi. Mole weight: 538.23 (free acid).
5-Aminoallyl-dU CEP
5-Aminoallyl-dU CEP is an essential component in the biomedical sector, extensively utilized for the research and development of modified nucleoside analogs, thus possessing distinctive utilities in the realm of medical investigation. Its significance prevails in the development of therapeutics intended to combat a myriad of ailments encompassing cancer, viral infections and neurodegenerative disorders. Synonyms: 5-TFA-aminoallyl-dU Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propen-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-[(trifluoroacetyl)amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥98% by HPLC. CAS No. 144253-90-7. Molecular formula: C44H51F3N5O9P. Mole weight: 881.87.
5-Aminoallyluridine-5'-Triphosphate
5-Aminoallyluridine-5'-Triphosphate, a fundamental component in molecular biology practices, serves as a crucial reagent for RNA-labeling processes. This particular compound efficiently integrates modified nucleotides into artificially synthesized RNA strands - a crucial step preceding further evaluation. Its utility extends to being an indispensable instrument for in-depth study of RNA's structural and functional characteristics. Synonyms: 5-AA-UTP; 5-(3-Amino-1-propenyl)uridine 5'-triphosphoric acid; uridine 5'-(tetrahydrogen triphosphate), 5-(3-amino-1-propenyl)-(E)-. Grade: ≥95% by AX-HPLC. CAS No. 161441-79-8. Molecular formula: C12H20N3O15P3. Mole weight: 539.20.
5-Aminobenzofuran
5-Benzofuranamine is used as a reagent in preparation of substituted pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors with a potential antitumor activity. Synonyms: 5-benzofuranamine; 1-benzofuran-5-amine. CAS No. 58546-89-7. Molecular formula: C8H7NO. Mole weight: 133.15.
5'-Amino-G-Monophosphate
5'-Amino-G-Monophosphate is an indispensable biomedical entity, renders itself useful in the research of specific neurological maladies. By serving as a nucleotides, it actively facilitates the manufacturing of neurotransmitters, instilling a sense of vibrancy in cerebral activities. In addition, this paramount compound assumes a pivotal position in DNA and RNA generation, thereby facilitating seamless cellular intercommunication and fostering neurological resilience in its entirety. Synonyms: 5'-Amino-GMP; Aminohexyl-GMP. Grade: ≥90% by AX-HPLC. Molecular formula: C16H27N6O8P. Mole weight: 462.40.
5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate, a paramount compound within the biomedical sector, serves as a pivotal substrate for enzymes that partake in cellular energy metabolism, ultimately bolstering ATP synthesis. Moreover, it exerts profound influence on multifarious cellular mechanisms and signaling cascades. Synonyms: AICAR Triphosphate; ZTP. CAS No. 82989-82-0. Molecular formula: C9H17N4O14P3. Mole weight: 498.17.
A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective. Synonyms: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-13C2,15N; AICAR-13C2,15N; Acadesine-13C2,15N; 5-Amino-4-imidazolecarboxamide Riboside-13C2,15N; Arasine-13C2,15N; GP 1-110-13C2,15N; NSC 105823-13C2,15N. Grade: 98.93% by HPLC; 99.7% atom 13C, 15N. CAS No. 1609374-70-0. Molecular formula: C7[13C]2H14N3[15N]O5. Mole weight: 261.21.
A labelled nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective. Synonyms: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside-15N4; AICAR-15N4; Acadesine-15N4; 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide-15N4; 5-Amino-4-imidazolecarboxamide Riboside-15N4; Arasine-15N4; GP 1-110-15N4; NSC 105823-15N4. Molecular formula: C9H14[15N]4O5. Mole weight: 262.2.
5-Aminoimidazole-4-carboxamide Lactose Adduct
5-Aminoimidazole-4-carboxamide Lactose Adduct is a lactose adduct of 5-Aminoimidazole-4-carboxamide, a metabolite of Temozolomide. Synonyms: Dacarbazine Lactose Adduct Impurity; 4-(((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-1H-imidazole-5-carboxamide. Grade: 98%. Molecular formula: C16H26N4O11. Mole weight: 450.40.
5-Aminoimidazole-4-carboxamide Lactose Adduct-13C2,15N is a labelled 5-Aminoimidazole-4-carboxamide Lactose Adduct, a lactose adduct of 5-Aminoimidazole-4-carboxamide which is a metabolite of Temozolomide. Synonyms: Dacarbazine Lactose Adduct Impurity-13C2,15N. Molecular formula: C14[13C]2H26N3[15N]O11. Mole weight: 453.38.
5-Aminoimidazole-4-carboxylic acid-1-b-D-ribofuranose 5'-monophosphate, aptly named as the Biomedical Wonder, emerges as an indispensable entity within the pharmaceutical realm. Its unparalleled significance lies in its profound involvement in combating diseases that afflict mankind - be it cancer, diabetes, or neurological disorders. Serving as a pivotal link in the intricate chain of nucleotide and coenzyme synthesis, this compound governs a multitude of vital cellular processes. Synonyms: 5-Amino-4-carboxyimidazole ribonucleotide; Carboxy-AIR; CAIR. CAS No. 6001-14-5. Molecular formula: C9H14N3O9P. Mole weight: 339.20.
5-Aminomethyl-2',3'-di-O-isopropylidene 2-thiouridine is a highly intricate and multifaceted compound widely employed in esteemed scientific investigations.This remarkable compound manifests significant promise in research of an array of ailments, such as cancer and viral afflictions. Synonyms: Uridine, 5-(aminomethyl)-2',3'-O-(1-methylethylidene)-2-thio-. Grade: ≥95%. CAS No. 1428903-07-4. Molecular formula: C13H19N3O5S. Mole weight: 329.37.
5-aminomethyl-2-thiouridine
5-Aminomethyl-2-thiouridine, a potent compound extensively utilized in the biomedical sector, exhibits substantial therapeutic potential across diverse disease domains such as cancer, viral infections, and neurodegenerative disorders. This multifaceted entity showcases remarkable efficacy owing to its distinctive molecular architecture, effectively directing its action towards targeted cellular pathways. The extensive range of prospective applications accentuates its status as a captivating avenue for stimulating forthcoming biomedical investigations and pharmaceutical advancements. Synonyms: Uridine, 5-(aminomethyl)-2-thio-. CAS No. 109666-14-0. Molecular formula: C10H15N3O5S. Mole weight: 289.31.
5-Aminomethyl-2-thiouridine hydrochloride
5-Aminomethyl-2-thiouridine hydrochloride is a profound biomedical compound, renowned for its antiviral prowess and showcasing immense potential in vanquishing notorious RNA viruses, including HIV. By actively obstructing viral replication, it galvanizes related research progress. Synonyms: 5-(aminomethyl)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one hydrochloride; 5-(aminomethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one hydrochloride. Grade: ≥95%. Molecular formula: C10H16ClN3O5S. Mole weight: 325.77.
5-Aminomethyluridine
5-Aminomethyluridine is a potent nucleoside analog extensively used in biomedical research. It exhibits antiviral activity against various viruses, including hepatitis C virus. Acting as a potent RNA-modifying agent, it is often employed to study RNA modifications and their implications in gene expression regulation and disease progression. Synonyms: 5-aminomethyluridine; 190448-73-8; SCHEMBL1665190. CAS No. 190448-73-8. Molecular formula: C10H15N3O6. Mole weight: 273.24.
5-Aminomethyluridine hydrochloride
5-Aminomethyluridine hydrochloride is a significant biomedical compound, serving as a pivotal role in the research of antiviral and antineoplastic medications. By selectively modulating intricate cellular mechanisms, it unveils promising potentials against viral infections as well as specific malignancies. Synonyms: 5-(aminomethyl)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione hydrochloride; 5-(Aminomethyl)uridine hydrochloride. Grade: 95%. Molecular formula: C10H16ClN3O6. Mole weight: 309.70.
5'-Amino Modifier
MMT-Hexylaminolinker Phosphoramidite is designed for use in automatic synthesizers to functionalize the sequence of the 5'end of the target oligonucleotide. The use of trityl-protected amino-modifiers is recommended when purification is required prior to use. Synonyms: 6-(4-Monomethoxytrityl)-hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-MMT-C6 Amino Modifier; 5'-Amino C6 Modifier Amidite. Grade: ≥95%. CAS No. 114616-27-2. Molecular formula: C35H48N3O3P. Mole weight: 589.75.
5'-Amino-Modifier 5
Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl[2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl] ester is an intricate biomedical compound, manifesting remarkable potential as a therapeutic agent for targeted drug delivery. Its distinctive mechanism centers on precise cellular pathway targeting, facilitating the hinderance of malignant proliferation and dissemination. Synonyms: 2-[2-(4-Monomethoxytrityl)aminoethoxy]ethyl-(2-cyanoethyl)-N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl [2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl] ester; 2-Cyanoethyl [2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl] N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl ester. CAS No. 612548-86-4. Molecular formula: C33H44N3O4P. Mole weight: 577.69.
5'-Amino-Modifier C12
5'-Amino Modifier is designed for use in automatic synthesizers to functionalize the sequence of the 5'end of the target oligonucleotide. The use of trityl-protected amino-modifiers is recommended when purification is required prior to use. Synonyms: 5'-Amino-Modifier C12-MMTr CE Phosphoramidite; 12-(4-Monomethoxytritylamino)dodecyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 12-[[(4-methoxyphenyl)diphenylmethyl]amino]dodecyl ester; MMT-C12-amine-linker Phosphoramidite; Monomethoxytrityl-C12-hexylamine-linker Phosphoramidite; 5'-Amino-Modifier C12 Phosphoramidite; 2-Cyanoethyl 12-[[(4-methoxyphenyl)diphenylmethyl]amino]dodecyl N,N-bis(1-methylethyl)phosphoramidite. Grade: >95%. CAS No. 178925-51-4. Molecular formula: C41H60N3O3P. Mole weight: 673.92.
5'-Amino-modifier-C12-DMT CEP
5'-Amino-modifier-C12-DMT CEP is a specialized reagent used in the synthesis of oligonucleotides. It features a 5'-amino modifier with a C12 spacer arm and a dimethoxytrityl (DMT) protecting group, along with a cyanoethyl phosphoramidite (CEP) functionality. The C12 spacer provides flexibility and distance between the oligonucleotide and the amino group, which can be used for further conjugation to other molecules. This compound is crucial for introducing functional groups at the 5' end of oligonucleotides, allowing for applications such as labeling, cross-linking, and attachment to solid supports in molecular biology and biotechnology research. Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 12-[[bis(4-methoxyphenyl)phenylmethyl]amino]dodecyl 2-cyanoethyl ester; DMT-C12-amine-linker amidite; 12-[[Bis(4-methoxyphenyl)phenylmethyl]amino]dodecyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite. Grade: ≥97%. CAS No. 1027512-19-1. Molecular formula: C42H62N3O4P. Mole weight: 703.94.
5'-Amino-Modifier C12 PDA
5'-Amino-Modifier C12 PDA: This compound is a versatile tool utilized in the biomedical industry for the modification of various biomolecules, such as oligonucleotides and peptides. It enables the attachment of a C12 alkyl chain to the 5'-end of these biomolecules, enhancing their stability and cellular uptake. Grade: >95% by HPLC. Molecular formula: C30H51N4O4P. Mole weight: 562.74.
5'-Amino-Modifier C12-PDA
5'-Amino-Modifier C12-PDA, a biomedical research reagent, is adept at oligonucleotide and DNA modification. Its versatility manifests in facilitating the conjugation of multiple molecules such as antibodies and fluorescent dyes, henceforth enabling diagnostic and therapeutic interventions. Synonyms: 12-(N²-methyl-N¹-phthalimidyl)-dodecyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C30H51N4O4P. Mole weight: 562.7.
5'-Amino-Modifier C3 PDA
5'-Amino-Modifier C3 PDA is an innovative compound renowned for its exceptional attributes in modifying nucleic acids. With remarkable efficiency, it facilitates seamless integration of amino groups at the 5' end of oligonucleotides, enabling versatile conjugation with myriad molecules. Grade: >95% by HPLC. Molecular formula: C21H33N4O4P. Mole weight: 436.49.
5'-Amino Modifier C3-TFA CE Phosphoramidite
5'-Amino Modifier C3-TFA CE Phosphoramidite is a valuable product used in the biomedical industry for the synthesis of modified nucleic acids. This phosphoramidite reagent allows for the introduction of an amino modifier group at the 5' position of nucleosides, enabling the creation of modified oligonucleotides with enhanced properties. It finds applications in various fields such as drug discovery, gene synthesis, and molecular diagnostics. Synonyms: 5'-Amino Modifier C3 TFA CE Phosphoramidite; 5'-Amino-modifier-C 3-tfa cep; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 3-[(trifluoroacetyl)amino]propyl ester; 2-Cyanoethyl 3-[(trifluoroacetyl)amino]propyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 3-[(trifluoroacetyl)amino]propyl ester; 5'-Amino-Modifier C3-TFA. CAS No. 853955-89-2. Molecular formula: C14H25F3N3O3P. Mole weight: 371.34.
5'-Amino-Modifier C6-PDA
5'-Amino-Modifier C6-PDA is an indispensable compound with its capacity to adhere to nucleic acids emerging as a compelling facilitator for seamless drug conveyance and gene manipulation. Its indispensable contribution in fabricating tailored research modalities for an array of afflictions such as cancer, hereditary anomalies and viral contagions is indeed noteworthy. Synonyms: 6-(N-methyl-N-phthalimidyl)-hexyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C24H39N4O4P. Mole weight: 478.57.
5'-Amino-Modifier TEG CE-Phosphoramidite
5'-Amino-Modifier TEG CE-Phosphoramidite is a chemical reagent commonly used in oligonucleotide synthesis. It is used to introduce an amino group at the 5' end of DNA or RNA sequences. This modification can be used to conjugate the oligonucleotide to other molecules, such as drugs, and to attach it to solid supports for use in diagnostic assays. The TEG spacer provides increased solubility and flexibility, while the CE-phosphoramidite group allows for facile incorporation during synthesis. Synonyms: 10-(O-trifluoroacetamido-N-ethyl)-triethyleneglycol-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C19H35F3N3O6P. Mole weight: 489.47.
5'-Amino-Modifier TEG PDA
5'-Amino-Modifier TEG PDA, an essential tool in the biomedical industry, bespeaks of its remarkable ability to modify oligonucleotides with an amine group, thereby, eloquently augmenting the binding properties of these molecules. Indeed, with its remarkable potential, this modification can prove an efficacious approach towards antisense therapy and RNA interference, making it indispensable for our biomedical arsenal. Grade: >95% by HPLC. Molecular formula: C26H43N4O7P. Mole weight: 554.62.
5'-Aminooxy-Modifier-11-CE Phosphoramidite
5'-Aminooxy-Modifier-11-CE Phosphoramidite is a critical component in the synthesis of modified RNA oligonucleotides used in biomedical research. This product is used to introduce aminooxy modifications into the RNA sequence, allowing for specific chemical conjugation reactions with drugs or disease biomarkers. These modified oligonucleotides can be used to study disease mechanisms, develop targeted drug delivery systems, and support gene therapy research. Synonyms: 10-[N-Dimethoxytrityl-aminooxyethyl)]-triethyleneglycol-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-DMT-Aminooxy-PEG4-phosphoramidite. Molecular formula: C38H54N3O8P. Mole weight: 711.82.
5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol
5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 5-aminoadamantane-1,3-diol; 3,5-dihydroxyadamantan-1-amine. CAS No. 1382839-19-1. Molecular formula: C10H17NO2. Mole weight: 183.25.
5-Aminouridine
5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. It therefore exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses. Synonyms: 5-Amino Uridine; 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Amino-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; NSC 72560. Grade: ≥95%. CAS No. 2149-76-0. Molecular formula: C9H13N3O6. Mole weight: 259.22.
5-Amino Uridine Hydrochloride
Has a wide range of biological effects including inhibiting the growth of bacteria, fungi, viruses, protozoa, and tumors. Uses: Has a wide range of biological effects including inhibiting the growth of bacteria, fungi, viruses, protozoa, and tumors. Synonyms: 5-Aminouridine Hydrochloride. Grade: 95%. CAS No. 116154-74-6. Molecular formula: C9H14ClN3O6. Mole weight: 295.68.
5'-AquaPhluor® 593 CE Phosphoramidite
5'-AquaPhluor® 593 CE Phosphoramidite, a premium compound of utmost finesse, plays a central role in the realm of oligonucleotide development. Its distinguished fluorescence labeling attribute is deftly infused into the backbone of oligonucleotides, vastly facilitating the discernment of DNA, RNA and DNA-protein interactions. Enabling cutting-edge genetic inquiry, this invaluable substance is a critical tool in biomedicine research, aiding in the detection and scrutiny of DNA and RNA sequences, as well as the diagnosis of genetic disorders. Synonyms: 6-[2,3,6,7,12,13,16,17-Octohydro-1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium-9-yl-[(2-diethylaminocarbonyl)-phen-4-yl][trifluoroacetylaminobutoxy]phosphoryl][oxy]]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite,hexafluorophosphate salt; 1H,5H,11H,15H-Quinolizino[1',9':5,6,7]xantheno[2,3,4-ij]quinolizin-18-ium, 9-[5-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxido-1-[4-[(2,2,2-trifluoroacetyl)amino]butoxy]-2,9,11-trioxa-1,10-diphosphatridec-1-yl]-2-[(diethylamino)carbonyl]phenyl]-2,3,6,7,12,13,16,17-octahydro-, hexafluorophosphate(1-) (1:1). CAS No. 2378004-17-0. Molecular formula: C57H78F9N6O8P3. Mole weight: 1239.17.
5'-AquaPhluor® 639 CE Phosphoramidite
5'-AquaPhluor® 639 CE Phosphoramidite is a chemical reagent widely used in the biomedicine industry for efficient labeling of synthetic oligonucleotides. This product is capable of introducing fluorescent dyes into the oligonucleotides for multi-color detection and analysis of RNA and DNA sequences. Its high brightness and stability make it suitable for use in various molecular diagnostic applications, including for infectious diseases, cancer diagnosis, and gene expression analysis. Synonyms: 6-[2,3,16,17-tetrahydro-5,5,7,11,13,13-hexamethyl-1H,5H,13H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium-9-yl-[2-chloro-6-(N-hydroxysulfonylethyl-N'-methylaminocarbonyl)-phen-4-yl][trifluoroacetylaminobutoxy]phosphoryl][oxy]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C62H82ClF3N6O11P2S. Mole weight: 1273.82.
5-Aza-2'-deoxy-6-oxo Cytidine
Used for preparation of azacytosine analogs and derivatives for the treatment of hematol disorders, tumors, and cancers. Uses: Used for preparation of azacytosine analogs and derivatives for the treatment of hematol disorders, tumors, and cancers. Synonyms: 6-Amino-3-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione. Grade: 95%. CAS No. 106966-55-6. Molecular formula: C8H12N4O5. Mole weight: 244.5.
5-Aza-2'-deoxy Cytidine-15N4
Labelled 5-Aza-2'-deoxy Cytidine used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one-15N4; 2-Desoxy-5-azacytidine-15N4; 2'-Deoxy-5-azacytidine-15N4; DAC-15N4; Dacogen-15N4; Decitabine-15N4; NSC 127716-15N4; β-Decitabine-15N4. Grade: 95%. Molecular formula: C8H12[15N]4O4. Mole weight: 232.18.
5-Aza-2'-deoxy Cytidine-15N4 5'-Monophosphate
A labelled metabolite of Azadeoxycytidine, as a neoplasm inhibitor. Synonyms: 4-Amino-1-(2-deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one-15N4. Molecular formula: C8H13[15N]4O7P. Mole weight: 312.16.
5-Aza-2'-deoxy Cytidine 5'-Monophosphate Triethylamine Salt
A metabolite of Azadeoxycytidine, as a neoplasm inhibitor. Synonyms: 4-Amino-1-(2-deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one Triethylamine Salt. CAS No. 97763-83-2. Molecular formula: C8H13N4O7P x(C6H15N). Mole weight: 308.19.
5-Aza-2'-deoxy Cytidine Diphosphate
5-Aza-2'-deoxy Cytidine Diphosphate is a derivative of Decitabine, which is a potent inhibitor of DNA methylation used to treat myelodysplastic syndromes (MDS). Synonyms: ((2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one Diphosphate; 2-Desoxy-5-azacytidine Diphosphate; 2'-Deoxy-5-azacytidine Diphosphate; DAC Diphosphate; Dacogen Diphosphate; Decitabine Diphosphate; NSC 127716 Diphosphate; β-Decitabine Diphosphate; 4-Amino-1-{2-deoxy-5-O-[hydroxy(phosphonooxy)phosphoryl]-β-D-erythro-pentofuranosyl}-1,3,5-triazin-2(1H)-one. Molecular formula: C8H14N4O10P2. Mole weight: 388.16.
5-Aza-2'-deoxyuridine (α/β mixture)
5-Aza-2'-deoxyuridine is a metabolite of 5-aza-2'-deoxycytidine, a cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 1-(2-Deoxy-D-erythro-pentofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione; 1-(2-Deoxy-D-erythro-pentofuranosyl)-s-triazine-2,4(1H,3H)-dione. Grade: 96%. Molecular formula: C8H11N3O5. Mole weight: 229.19.
5-Aza-2'-deoxyuridine (β Isomer)
5-Aza-2'-deoxyuridine is a metabolite of 5-aza-2'-deoxycytidine, a cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazine-2,4(1H,3H)-dione; 5-Aza-2'-deoxy-β-uridine. Grade: 96%. CAS No. 25501-08-0. Molecular formula: C8H11N3O5. Mole weight: 229.19.
5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine
5-Aza-3',5'-di-O-acetyl-2'-deoxycytidine is an influential pharmaceutical compound, showcasing remarkable antitumor attributes. Renowned for its versatile applications, it finds extensive research in combatting diverse malignancies such as leukemia, lung cancer and colon cancer. Functioning as a DNA methyltransferase inhibitor, its mechanism revolves around counteracting epigenetic alterations, thus facilitating the reinstatement of regular cellular operations. Molecular formula: C12H16N4O6. Mole weight: 312.28.
5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is an indispensable chemical constituent of RNA synthesis in the biomedical industry. This mediator modifies cytidine residues in RNA, thus benefitting cancer or viral treatment research. Furthermore, its remarkable purity and stability make it a perfect candidate for research and investigation purposes. Synonyms: 2'-O-Methyl 5-aza-3-deaza-N4-DMF-5'-DMT-D-cytidine 3'-CE phosphoramidite. Molecular formula: C43H55N6O8P. Mole weight: 814.91.