BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
10Panx is a mimetic inhibitory peptide of panx1. It blocks pannexin-1 gap junctions, inhibits p2x7-mediated dye uptake, atp-mediated il-1β release and caspase-1 activation, but does not alter membrane current in macrophages in vitro. Synonyms: 10PANX; H-Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr-OH; L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-alpha-aspartyl-L-seryl-L-tyrosine. Grade: >98%. CAS No. 955091-53-9. Molecular formula: C58H79N15O16. Mole weight: 1242.37.
1,10-Diaminodecane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)10-NH-Trt-Resin; Diaminodecane-Trt-Resin.
1,1,1,3,3,3-Hexafluoroisopropyl alcohol
It is used as a polar solvent and exhibits strong hydrogen bonding properties. It dissolves substances that are hydrogen-bond acceptors. Uses: 1,1,1,3,3,3-hexafluoroisopropanol, also known as hfip alcohol, is a powerful solvent with unique properties that are valuable in various research fields such as drug discovery. it contains six fluorine atoms in its chemical structure, which have strong electron-withdrawing properties and high polarity, making it ideal for certain applications in medicinal chemistry. finding novel therapeutic pros. Synonyms: 1,1,1,3,3,3-Hexafluoro-2-propanol; 1,1,1,3,3,3-Hexafluoro propan-2-ol. Grade: ≥ 99 % (GC). CAS No. 920-66-1. Molecular formula: C3H2F6O. Mole weight: 168.04.
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)12-NH-Trt-Resin; Diaminododecane-Trt-Resin.
11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1'as matrix metalloproteinase inhibitors. Synonyms: ω-Aminoundecanoic acid; Undecanoic acid, 11-amino-; 11-Aminoundecylic acid; 11-amino-undecanoic acid; H-11-Aun-OH. Grade: ≥ 99% (Titration). CAS No. 2432-99-7. Molecular formula: C11H23NO2. Mole weight: 201.31.
It is used in epoxidation reactions in organic synthesis. It is useful in preparing acyl triazolides from carboxylic acids. Synonyms: CDT; 1,1'-Carbonyl-di-(1,2,4-triazole). Grade: ≥ 98% (Titration). CAS No. 41864-22-6. Molecular formula: C5H4N6O. Mole weight: 164.13.
11-Maleimidoundecanoic acid is a crosslinking reagent for conjugating biochemicals to the polymer chain. Synonyms: N-(10-Carboxydecyl)maleimide; 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-undecanoic Acid; KMUA; UNII-LG78EY7HVB; maleimidoundecanoic acid; AM-10; MUDA; 1H-Pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo-; LG78EY7HVB; Maleimide-(CH2)10-COOH; N-(10-Carboxydecyl)maleimide. Grade: 99% (HPLC). CAS No. 57079-01-3. Molecular formula: C15H23NO4. Mole weight: 281.35.
1,1-Sulfonylbis(2-methyl-1H-imidazole)
1,1-Sulfonylbis(2-methyl-1H-imidazole) (CAS# 489471-87-6) is a useful research chemical compound. Synonyms: 2-methyl-1-[(2-methyl-1-imidazolyl)sulfonyl]imidazole; 2-methyl-1-(2-methylimidazol-1-yl)sulfonylimidazole. CAS No. 489471-87-6. Molecular formula: C8H10N4O2S. Mole weight: 226.26.
123C4 is an effective, selective and competitive receptor tyrosine kinase EPHA4 agonist with a Ki value of 0.65 μM. Synonyms: 4-amino-N-((S)-1-(((S)-3-(4-chlorophenyl)-1-(((S)-1-((2-(5-methoxy-1H-indol-3-yl)ethyl)amino)-1-oxo-3-(pyridin-4-yl)propan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-(5-hydroxy-1H-indol-3-yl)-1-oxopropan-2-yl)butanamide. Grade: ≥98%. CAS No. 2034159-30-1. Molecular formula: C43H47ClN8O6. Mole weight: 807.34.
1-(2,4-Dinitrophenyl)-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide is a peptide that can facilitate the interaction between antibodies and their corresponding antigens. Synonyms: Dnp-Pro-Leu-Gly-Ile-Ala-Gly-Arg-NH2. CAS No. 60643-92-7. Molecular formula: C36H57N13O11. Mole weight: 847.92.
12-Aminolauric Acid is an amino acid used as a reagent in organic synthesis of several compounds including phenylbutazone which is a new long-acting agent which displays improved pharmacokinectics based on human serum albumin as a drug carrier. Synonyms: 12-Aminolauric acid; 12-Ado-OH; 12-Aminododecanoic acid; 12-AMINO-DODECANOIC ACID; Dodecanoic acid, 12-amino-; omega-Aminolauric acid; Omega-Aminododecanoic acid; 12-aminododecanic acid; H-Adod(12)-OH. Grade: ≥ 99% (Titration). CAS No. 693-57-2. Molecular formula: C12H25NO2. Mole weight: 215.34.
1,2-Cyclopentanediol, 3-amino-5-[(phosphonooxy)methy]-, ammonium salt (1:2), (1R,2S,3R,5R)-
A useful research chemical. CAS No. 1388152-02-0. Molecular formula: C6H14NO6P. Mole weight: 227.
1,2-Diaminoethane trityl resin
1,2-Diaminoethane trityl resin.
1,2-Dierucoyl-sn-glycero-3-phosphocholine
1,2-Dierucoyl-sn-glycero-3-phosphocholine is a phosphocholine with erucic acid. It can be used in formulation of micelles, liposomes, and other types of artificial membranes. Synonyms: DEPC; L-Dierucoyl lecithin; (7R,22Z)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[[(13Z)-1-oxo-13-docosen-1-yl]oxy]-3,5,9-trioxa-4-phosphahentriacont-22-en-1-aminium 4-Oxide Inner Salt; [R-(Z,Z)]-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-13-docosenyl)oxy]-3,5,9-trioxa-4-phosphahentriacont-22-en-1-aminium Inner Salt 4-Oxide; Dierucoyl-L-α-glycerophosphorylcholine; Dierucoyllecithin; 1,2-di-(13Z-docosenoyl)-sn-glycero-3-phosphocholine. Grade: >98% by HPLC. CAS No. 51779-95-4. Molecular formula: C52H100NO8P. Mole weight: 898.32.
1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine sodium salt
DPPS (1,2-Dipalmitoyl-sn-glycero-3-phosphoserine, sodium salt) is a form of phosphatidylserine (PS), a negatively charged phospholipid located in the inner leaflet of the cell membrane. Synonyms: L-Serine, (2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl hydrogen phosphate (ester), monosodium salt; L-Serine, 2,3-bis[(1-oxohexadecyl)oxy]propyl hydrogen phosphate (ester), monosodium salt, (R)-; 4,6,10-Trioxa-5-phosphahexacosanoic acid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide, sodium salt (1:1), (2S,8R)-; Coatsome MS 6060LS; 1,2-Dipalmitoyl-sn-glycero-3-phosphoserine sodium salt; L-α-Dipalmitoylphosphatidylserine sodium salt; DPPS sodium salt; monosodium mono(O-(((R)-2,3-bis(palmitoyloxy)propoxy)oxidophosphoryl)-L-serinate). Grade: ≥98%. CAS No. 145849-32-7. Molecular formula: C38H73NO10P.Na. Mole weight: 758.00.
1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt
It has been used to physically stabilize emulsions and suspensions. It is also used in formulations of pulmonary surfactants, intravenous fat emulsions, and oral solutions. Synonyms: Dipalmitoyl phosphatidylglycerol, sodium salt; 1,2-Dihexadecanoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] sodium salt; sodium 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol); 1,2-Dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt; DPPG-Na; L-DPPG-Na; Hexadecanoic acid, 1,1'-(1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl) ester, sodium salt (1:1). Grade: >98%. CAS No. 67232-81-9. Molecular formula: C38H74NaO10P. Mole weight: 744.95.
1,2-Distearoyl-sn-glycero-3-phosphoglycerol sodium salt
1,2-distearoyl-sn-glycero-3-phosphatidyl-rac-glycerol sodium salt is a form of phosphatidylglycerol (PG), a minor component (1-2%) of most of cell membranes. It can be found at higher concentrations (up to 11% of the total lipid content) in lung surfactant. It is presence in amniotic fluid indicates fetal lung maturity and is the basis of clinical testing for fetal fitness. PG is also used by cells as an intermediate in cardiolipin synthesis. Bacterial membranes contain up to 20% of PG. Synonyms: DSPG sodium; Octadecanoic acid, 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, sodium salt. Grade: > 98%. CAS No. 124011-52-5. Molecular formula: C42H83O10P.xNa. Mole weight: 779.08 (free base).
1,3-Bis-(Z-Leu-Leu)-diaminoacetone, a cysteine protease inhibitor, can specifically and efficiently inhibit the processing of p-Prl signal peptide (IC50 ca. 50 nM) without affecting the activity of signal peptidase and lysosomal cathepsin, proteasome, and other proteases. Synonyms: (Z-LL)2 Ketone; Z-Leu-Leu-NH-CH2-CO-CH2-NH-Leu-Leu-Z; 2,2'-(2-Oxo-1,3-propanediyl)bis[N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucinamide; 1,3-di-(N-carboxybenzoyl-leucyl-leucyl)aminoacetone; Dibenzyl [(4S,7S,15S,18S)-7,15-diisobutyl-2,20-dimethyl-5,8,11,14,17-pentaoxo-6,9,13,16-tetraazahenicosane-4,18-diyl]biscarbamate. Grade: ≥95%. CAS No. 313664-40-3. Molecular formula: C43H64N6O9. Mole weight: 809.00.
1,3-Diaminopropane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)3-NH-Trt-Resin; Diaminopropane-Trt-Resin.
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-CH2-Bzl-NH-Trt-Resin; 1,4-Bis(aminomethyl)-benzene-Trt-Resin.
1,4-Dioxaspiro(4.5)Decane-8-Carbonitrile
1,4-Dioxaspiro(4.5)Decane-8-Carbonitrile (CAS# 69947-09-7) is used to prepare 1,2-dihydroquinolin-2-one and 1,2-dihydroquinoxalin-2-one derivatives as antibacterial agents. It is also used in the synthesis of heterocyclic sulfonamides as oral GlyT1 inhibitors. Synonyms: 4-Cyanocyclohexanone Ethylene Acetal; 8-Cyano-1,4-dioxaspiro[4.5]decane. CAS No. 69947-09-7. Molecular formula: C9H13NO2. Mole weight: 167.2.
This is used in the preparation of Nephilatoxin analogues.
1,6-Diaminohexane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)6-NH-Trt-Resin; Diaminohexane-Trt-Resin.
1,7-Diaminoheptane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)7-NH-Trt-Resin; Diaminoheptane-Trt-Resin.
18:0 PA (sodium salt)
DSPA (1,2-distearoyl-sn-glycero-3-phosphate) is a phospholipid containing a phosphatidic acid head group and 18:0 fatty acids at the sn-1 and sn-2 positions of the glycerol backbone. DSPA has been used to study the dynamics of model lipid bilayers via its negative charge. Uses: The study of lipid bilayers' dynamics. Synonyms: 1,2-distearoyl-sn-glycero-3-phosphate (sodium salt); DSPA-Na; Sodium (R)-2,3-bis(stearoyloxy)propyl hydrogenphosphate. Grade: ≥98%. CAS No. 108321-18-2. Molecular formula: C39H76NaO8P. Mole weight: 726.98.
18:1 PA (sodium salt)
DOPA (1,2-dioleoyl-sn-glycero-3-phosphate) is an anionic lipid. Uses: Dopa may be used as a component in liposomes/lipid bilayers, and an activator of multiple pkc isotypes. Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphatidic acid (sodium salt); DOPA-Na; 1,2-Dioleoyl-sn-glycero-3-PA. Grade: 98%. CAS No. 108392-02-5. Molecular formula: C39H73NaO8P. Mole weight: 723.95.
1,8-Diaminooctane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)8-NH-Trt-Resin; Diaminooctane-Trt-Resin.
1,8-Diazabicyclo[5.4.0]undec-7-ene
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) can promote the methylation reaction of phenols, indoles and benzimidazoles with dimethyl carbonate under mild conditions. Synonyms: DBU; 1,8-Diazabicyclo[5.4.0]undecene-7; Alcanpoudre DBU 70-3KG; Amicure DBUE; Dabco DBU; Lupragen N 700; NSC 111184; NSC 230466; PC CAT DBU; Polycat DBU; U-CAT SA 851. Grade: ≥ 98%. CAS No. 6674-22-2. Molecular formula: C9H16N2. Mole weight: 152.24.
1,9-Diaminononane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Synonyms: NH2-(CH2)9-NH-Trt-Resin; Diaminononane-Trt-Resin.