BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Zinc pivalate | Zinc pivalate (CAS# 15827-10-8 ) is a useful research chemical. Synonyms: Zinc(II) pivalate; Bis(pivaloyloxy) zinc; Zn(OPiv)2; Propanoic acid, 2,2-dimethyl-, zinc salt (2:1). Grades: 95 %. CAS No. 15827-10-8. Molecular formula: C10H18O4Zn. Mole weight: 267.64. |  |
| Zingiberensis saponin I | Zingiberensis saponin I is a compound of the steroidal saponins isolated from Dioscorea zingiberensis C. H. Wright with inhibitory effect on platelet aggregation and cancer cell proliferation. Synonyms: Deltonin glucoside; Glucopyranosyl-(1-3)-deltonin; Beta-D-Glucopyranoside, (3beta,25R)-spirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(O-beta-D-glucopyranosyl-(1-3)-beta-D-glucopyranosyl-(1-4))-, (S-(R*,R*))-. Grades: >98%. CAS No. 91653-50-8. Molecular formula: C51H82O22. Mole weight: 1047.195. | |
| ZJ 43 | ZJ 43 is a potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III/NAAG peptidase/NAALADase) (Ki = 0.8 and 23 nM, respectively). It inhibits the hydrolysis of NAAG (IC50 = 2.4 nM) and decreases the deleterious effects of excessive extracellular glutamate. ZJ 43 has been shown to reduce neuronal degeneration in a rat model of traumatic brain injury (TBI) and reduce locomotor activity in the PCP-model of schizophrenia. Synonyms: ZJ 43; ZJ43; ZJ-43; N-[[[(1S)-1-Carboxy-3-methylbutyl]amino]carbonyl]-L-glutamic acid; (2S) -2- [ [ (1S) -1-carboxy-3-methylbutyl] carbamoylamino] pentanedioic acid. CAS No. 723331-20-2. Molecular formula: C12H20N2O7. Mole weight: 304.3. | |
| ZK-304709 | ZK 304709 is a oral multitarget tumour growth inhibitor inhibits growth of pancreatic neuroendocrine tumours in an orthotopic mouse model. Uses: Potent multi-target tumor. Synonyms: ZK304709; ZK 304709; ZK304709; (S)-4-((5-bromo-4-((1-hydroxypropan-2-yl)amino)pyrimidin-2-yl)amino)benzenesulfonamide. Grades: ≥98%. CAS No. 477588-78-6. Molecular formula: C13H16BrN5O3S. Mole weight: 402.27. | |
| (Z)-MDL 105519 | (Z)-MDL 105519 is the inactive isoform of MDL 105519 which is a high affinity NMDA glutamate receptor antagonist at the glycine site. Synonyms: (Z)-MDL 105519; (Z)-MDL105519; (Z)-MDL-105519. CAS No. 179105-67-0. Molecular formula: C18H11Cl2NO4. Mole weight: 376.19. | |
| Zoliflodacin | Zoliflodacin, an oxazolidinone derivative, has been found to be a DNA gyrase inhibitor that could be used as an antibacterial agent. It is still under Phase II trial in Gonorrhea. Uses: Topoisomerase ii inhibitors. Synonyms: UNII-FWL2263R77; AZD-0914; AZD0914; AZD 0914; FWL2263R77; FWL 2263R77; FWL-2263R77; Zoliflodacin; AZD0914; CHEMBL3544978; (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-((S)-4-methyl-2-oxooxazolidin-3-yl)-1,2,4,4a-tetrahydro-2'H,6H-spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1. Grades: 98%. CAS No. 1620458-09-4. Molecular formula: C22H22FN5O7. Mole weight: 487.40. | |
| Zoniporide dihydrochloride | Zoniporide dihydrochloride is a potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with selectivity over other NHE isoforms (Ki = 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3, respectively). Zoniporide inhibits NHE1-dependent 22Na+ uptake in vitro (IC50 = 14 nM) and protects against cardiac ischemia-reperfusion injury. Zoniporide also exhibits inhibitory effects on MMP2/9 in breast cancer cells. Synonyms: [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride; CP 597396. Grades: ≥99% by HPLC. CAS No. 241799-10-0. Molecular formula: C17H16N6O.2HCl. Mole weight: 393.27. | |
| Zoniporide hydrochloride | Zoniporide hydrochloride is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1), which is mostly expressed in the heart. Zoniporide inhibits NHE1-dependent Na+ uptake (IC50: 14 nM) and protects from cardiac ischemia-reperfusion injury (EC50 = 0.25 nM). Synonyms: N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide monohydrochloride. Grades: 99%. CAS No. 241800-97-5. Molecular formula: C17H16N6O.HCl. Mole weight: 356.81. | |
| Zonisamide | Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Uses: Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive t-type calcium currents. heterocyclic methanesulfonide with anticonvulsant properties. the compound is under investigation for potent. Synonyms: AD-810; AD-810N; AD 810; AD 810N; AD810; AD810N; 1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole. Grades: ≥98%. CAS No. 68291-97-4. Molecular formula: C8H8N2O3S. Mole weight: 212.23. | |
| Zosuquidar | Zosuquidar, also called as LY335979, a cyclopropyldibenzosuberane, was developed as an inhibitor of P-glycoprotein (P-gp). It is undergoing testing in a phase I/II trial clinical study in acute myeloid leukaemia. Synonyms: (2R)-anti-5-(3-(4-(10,11-difluoromethanodibenzo-suber-5-yl)piperazin-1-yl)2-hydroxypropoxy)quinoline trihydrochlorideLY 335979; LY-335979LY335979RS 33295-198RS-33295-198zosuquidar trihydrochloride. CAS No. 167354-41-8. Molecular formula: C32H31F2N3O2. Mole weight: 527.60. | |
| Z-Phe-DL-Ala-FMK | Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages. Uses: Cysteine proteinase inhibitors. Synonyms: Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester. Grades: ≥95%. CAS No. 197855-65-5. Molecular formula: C21H23FN2O4. Mole weight: 386.42. | |
| (Z)-Pitavastatin Calcium Salt | An impurity of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Synonyms: (Z)-Pitavastatin Calcium Salt; 1159588-21-2; (Z,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate. Grades: > 95%. CAS No. 1159588-21-2. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01. | |
| ZQ 16 | ZQ 16 is a selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM), displaying no activity at GPR40, GPR41, GPR119 or GPR120 at 100 μM. ZQ 16 activates GPR84-mediated calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro. Synonyms: ZQ 16; ZQ16; ZQ-16; 2-(Hexylthio)-6-hydroxy-4(3H)-pyrimidinone. Grades: ≥98% by HPLC. CAS No. 376616-73-8. Molecular formula: C10H16N2O2S. Mole weight: 228.31. | |
| (Z)-SMI-4a | (Z)-SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM for Pim-1 compared to an IC50 of 100 nM for Pim-2 and with little or no activity against a panel of 50 other kinases tested. Synonyms: SMI-4a; SMI4a; SMI 4a; TCS PIM-1 4a. CAS No. 438190-29-5. Molecular formula: C11H6F3NO2S. Mole weight: 273.229. | |
| Zunsemetinib | Zunsemetinib is a tyrosine kinase inhibitor. Synonyms: [1(2H),4'-Bipyridin]-2-one, 3-chloro-4-[(3,5-difluoro-2-pyridinyl)methoxy]-2'-[2-(1-hydroxy-1-methylethyl)-4-pyrimidinyl]-5',6-dimethyl-, (-)-. Grades: >98%. CAS No. 1640282-42-3. Molecular formula: C25H22ClF2N5O3. Mole weight: 513.92. | |
| Z-VAD-FMK | Z-VAD-FMK is a broad spectrum pan-caspase inhibitor that inhibits the intracellular activation of caspase-like proteases. Synonyms: Z-VAD (OMe)-FMK; Caspase Inhibitor I. Grades: >98.0%. CAS No. 187389-52-2. Molecular formula: C22H30FN3O7. Mole weight: 467.49. | |
| Z-Val-Gly-Arg-pNA | Synonyms: L-Argininamide, N-[(phenylmethoxy)carbonyl]-L-valylglycyl-N-(4-nitrophenyl)-; N-[(Phenylmethoxy)carbonyl]-L-valylglycyl-N-(4-nitrophenyl)-L-argininamide; Chromozym TRY; Cbz-Val-Gly-Arg-pNA; Benzyl ((S)-1-((2-(((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-3-methyl-1-oxobutan-2-yl)carbamate. Grades: ≥95%. CAS No. 78333-16-1. Molecular formula: C27H36N8O7. Mole weight: 584.62. | |
| Z-VDVAD-FMK | Z-VDVAD-FMK is a cell-permeant and irreversible caspase-2 inhibitor and can inhibits apoptosis in various cell lines. Synonyms: Z-VD(OMe)VAD(OMe)-FMK; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethyl ketone; benzyloxycarbonyl-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-|A-aspartyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK. Grades: ≥95%. CAS No. 210344-92-6. Molecular formula: C32H46FN5O11. Mole weight: 695.74. | |
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