BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tanshinone IIA | Tanshinone IIA, under the IUPAC name 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione, one of the original anthracyclines isolated from Salvia miltiorrhiza, inhibits β-amyloid aggregation and protects PC12 cells from β-amyloid-induced apoptosis. Tanshinone IIA is a natural compound which has anti-oxidative properties, can be used in cosmetics material. Uses: Anti-alzheimer agents; amyloid-β inhibitor; anti-infective agents; anti-inflammatory agents; immunosuppressive agents; anticoagulants; antineoplastic agents, phytogenic. Synonyms: Tanshinone IIA; 568-72-9; Tanshinone II; Dan Shen Ketone; Tanshinone B; Tanshinon II; 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione; C19H18O3; MLS001048863; NSC686519; NSC 686518; SMR000387068; Tanshinone B, Tanshinone II, 568-72-9; 1,6,6-trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dion; 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-dione; 1,6,6-. Grade: 0.985. CAS No. 568-72-9. Molecular formula: C19H18O3. Mole weight: 294.34. |  |
| Tanshinone IIB | Tanshinone IIB isolated from the roots of Salvia miltiorrhiza. It inhibits the uptake of digoxin and vinblastine in membrane vesicles containing PgP or MRP1, moderately stimulates PgP ATPase activity. Uses: Neuro-protective; antioxidant. Synonyms: (S)-6-(HydroxyMethyl)-1,6-diMethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione. Grade: 0.97. CAS No. 17397-93-2. Molecular formula: C19H18O4. Mole weight: 310.4. | |
| Taraxasterol | Taraxasterol is isolated from the herbs of Taraxacum officinale. It inhibits NO, PGE(2), TNF-α, IL-1β and IL-6 production in LPS-induced RAW 264.7 macrophages in a dose-dependent manner. Synonyms: (18α,19α)-5α-Urs-20(30)-en-3β-ol; Anthesterin; Taraxasta-20(30)-ene-3β-ol; Isolactucerol. Grade: 98%. CAS No. 1059-14-9. Molecular formula: C30H50O. Mole weight: 426.72. | |
| Taraxerol | Taraxerol, isolated from the herb of Taraxacum mongolicum Hand. Mazz., is a cancer chemopreventive agent. Uses: Ache activity; antiulcer. Synonyms: alnulin; D-Friedoolean-14-en-3beta-ol; skimmiol; (3β,13α)-13-Methyl-27-norolean-14-en-3-ol; (3β)-D-Friedoolean-14-en-3-ol. Grade: 98.5%. CAS No. 127-22-0. Molecular formula: C30H50O. Mole weight: 426.7. | |
| Taraxerone | Taraxerone is isolated from the herb of Taraxacum mongolicum Hand. Mazz. It can prevent catalase and superoxide dismutase, and reduce glutathione concentration. Synonyms: D-Friedoolean-14-en-3-one; Taraxera-14-ene-3-one; Taraxeron; 27-Norolean-14-en-3-one,13-methyl-, (13a)-; Tarxerone; 27-Norolean-14-en-3-one, 13-methyl-, (13α)-. Grade: 98.5%. CAS No. 514-07-8. Molecular formula: C30H48O. Mole weight: 424.7. | |
| Tatsinine | Tatsinine is a potential natural compound in natural compound used for the research of various cancers. With its unique chemical structure, it has shown promising anti-tumor activity by inhibiting specific signaling pathways involved in cancer progression. Synonyms: 20-ethyl-16-methoxy-4-methylaconitane-1,7,8,9,14-pentol. Grade: 97.0%. CAS No. 90038-21-4. Molecular formula: C22H35NO6. Mole weight: 409.523. | |
| Taxachitriene B | Taxachitriene B is extracted from the needles of the Chinese yew Taxus chinensis. Synonyms: (2R,3E,5S,7S,8E,10S,11R,13S)-10-hydroxy-8-(hydroxymethyl)-4,14,15,15-tetramethylbicyclo[9.3.1]pentadeca-1(14),3,8-triene-2,3,5,7,13-pentayl pentaacetate; Bicyclo[9.3.1]pentadeca-3,8,14-triene-2,3,5,7,10,13-hexol, 8-(hydroxymethyl)-4,14,15,15-tetramethyl-, 2,3,5,7,13-pentaacetate, (2R,3E,5S,7S,8E,10S,11R,13S)-. Grade: 98.0%. CAS No. 167906-75-4. Molecular formula: C30H42O12. Mole weight: 594.65. | |
| Taxacin | Taxacin is a natural diterpenoid compound found in several plants. Synonyms: (1S,3aR,4R,5R,5aR,7S,9S,9aR,10R,11S,11aR)-9a-((benzoyloxy)methyl)-7-(cinnamoyloxy)-11a-hydroxy-1,3a-dimethyl-6-methylene-13-oxotetradecahydro-1,4-ethanobenzo[5,6]cycloocta[1,2-c]furan-5,9,10,11-tetrayl tetraacetate. Grade: >97%. CAS No. 117229-54-6. Molecular formula: C44H48O15. Mole weight: 816.84. | |
| Taxayunnansin A | Taxayunnansin A is isolated from the barks of Taxus chinensis. Synonyms: (2aR,4S,4aS,5R,6R,8S,9aS,10S,10aR,10bS)-6-(benzoyloxy)-8-hydroxy-9a-(2-hydroxypropan-2-yl)-4a,7-dimethyl-3,4,4a,5,6,8,9,9a,10,10a-decahydro-1H-azuleno[5',6':3,4]benzo[1,2-b]oxete-4,5,10,10b(2aH)-tetrayl tetraacetate. Grade: > 95%. CAS No. 153229-31-3. Molecular formula: C35H44O13. Mole weight: 672.7. | |
| Taxcultine | Taxol D is an impurity of Paclitaxel, an antineoplastic. It is used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Synonyms: Baccatin III 13-ester with (2R,3S)-3-butanoylamino-2-hydroxy-3-phenylpropanoic acid; Paclitaxel Propyl analog; Benzenepropanoic acid, α-hydroxy-β-[(1-oxobutyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; B. Grade: 98%. CAS No. 153415-46-4. Molecular formula: C44H53NO14. Mole weight: 819.89. | |
| Taxifolin | Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on. Taxifolin has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. Uses: Anti-tumor; anti-cancer; anti-inflammatory; antifungal; antioxidant ability. Synonyms: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-; (2R,3R)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R-trans)-; Flavanone, 3,3',4',5,7-pentahydroxy-; (+)-(2R,3R)-Dihydroquercetin; (+)-Dihydroquercetin; (+)-Taxifolin; (+)-trans-Taxifolin; (2R,3R)-(+)-Taxifolin; (2R,3R)-3,3',4',5,7-Pentahydroxyflavanone; (2R,3R)-Dihydroquercetin; 2,3-Dihydroquercetin; 3,5,7,3',4'-Pentahydroxyflavanone; Dihydroquercetin; Diquertin; Distylin; Flamena; Flamena D; Flavomix; HSA 8432; Jikuberuchin; Lariksin; Lavitol; Taxifoliol. Grade: >98%. CAS No. 480-18-2. Molecular formula: C15H12O7. Mole weight: 304.25. | |
| Taxifolin 3'-O-glucoside | Taxifolin 3'-O-glucoside is isolated from the leaves of Chamaecyparis obtuse. Synonyms: 4H-1-Benzopyran-4-one, 2-(3-(beta-D-glucopyranosyloxy)-4-hydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-. Grade: 98.0%. CAS No. 31106-05-5. Molecular formula: C21H22O12. Mole weight: 342.29. | |
| Taxin B | Taxin B is extracted from the seeds of Taxus mairei. It has toxic effects. Synonyms: Tricyclo(9.3.1.14,8)hexadeca-4,10-dien-2-one, 3,6,9,14-tetrakis(acetyloxy)-12-hydroxy-1,5,16,16-tetramethyl-, (1S,3R,6S,8R,9S,10E,12S,14S)-. Grade: 98.0%. CAS No. 168109-52-2. Molecular formula: C28H38O10. Mole weight: 534.60. | |
| Taxinine B | Taxinine B is isolated from the barks of Taxus chinensis, and it has strong inhibitory effects against AA-induced aggregation. Synonyms: 2-Propenoic acid, 3-phenyl-, (1S,3S,4aR,5R,6R,11R,12R,12aS)-1,5,11,12-tetrakis(acetyloxy)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-9,12a,13,13-tetramethyl-4-methylene-8-oxo-6,10-methanolobenzocyclodecen-3-yl ester, (2E)-. Grade: > 95%. CAS No. 18457-44-8. Molecular formula: C37H44O11. Mole weight: 664.8. | |
| Taxinine M | Taxinine M is extracted from the seeds of Chinese yew Taxus chinensis. Synonyms: 1,4-Ethanobenzo[5,6]cycloocta[1,2-c]furan-13-one, 5,9,10,11-tetrakis(acetyloxy)-9a-[(benzoyloxy)methyl]tetradecahydro-7,11a-dihydroxy-1,3a-dimethyl-6-methylene-, (1S,3aR,4R,5R,5aR,7S,9S,9aR,10R,11S,11aR)-; (2α,5α,7β,9α,10β,12α)-2,7,9,10-Tetraacetoxy-5,11-dihydroxy-13-oxo-12,17-epoxytax-4(20)-en-19-yl benzoate. Grade: 98.0%. CAS No. 135730-55-1. Molecular formula: C35H42O14. Mole weight: 686.70. | |
| Taxiphyllin | Taxiphyllin isolated from the herbs of Pleioblastus amarus (Keng) Keng f. It can inhibit tyrosinase activity in vitro significantly, so it is a potent tyrosinase inhibitor. Uses: Antibacterial activity. Synonyms: (R)-4-hydroxymandelonitrile β-D-glucoside; (2R)-Taxiphyllin. Grade: 98%. CAS No. 21401-21-8. Molecular formula: C14H17NO7. Mole weight: 311.3. | |
| Taxumairol B | Taxumairol B is extracted from the seeds of Taxus yunnanensis. Synonyms: 1-Hydroxy-7,9-dideacetylbaccatin I; 2,5,10,13-Tetraacetoxy-1,7,9-trihydroxy-4,20-epoxytax-11-ene. Grade: 98.0%. CAS No. 142203-64-3. Molecular formula: C28H40O12. Mole weight: 568.61. | |
| Tectochrysin | Tectochrysin is a flavonoid isolated from the heartwood of Pinus strobus L. It leads to apoptotic cell death in NSCLC cells through activating of DR3 and Fas expression. Uses: Antioxidant. Synonyms: 5-hydroxy-7-methoxyflavone; 5-Hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one. Grade: 99%. CAS No. 520-28-5. Molecular formula: C16H12O4. Mole weight: 268.3. | |
| Tectorigenin | Tectorigenin induced differentiation of human promyelocytic leukemia HL-60 cells to granulocytes and monocytes/macrophages, and caused apoptotic changes of DNA in the cells, as did genistein. Tectorigenin also inhibited autophosphorylation of epidermal growth factor (EGF) receptor by EGF and decreased the expression of Bcl-2 protein, with less activity than genistein. From these results, tectorigenin may be a possible therapeutic agent for leukemia. Uses: Antioxidant. Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-; Isoflavone, 4',5,7-trihydroxy-6-methoxy-; 5,7,4'-Trihydroxy-6-methoxyisoflavone; K 251T; Tectrigenin. Grade: >98%. CAS No. 548-77-6. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Tectoroside | Tectoroside is a natural sesquiterpene compound found in several plants. Synonyms: (3aR,4R,6aR,8S,9aR,9bR)-3,6,9-trimethylene-2-oxo-8-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)dodecahydroazuleno[4,5-b]furan-4-yl 2-hydroxy-3-(4-hydroxyphenyl)propanoate. Grade: >98%. CAS No. 124960-89-0. Molecular formula: C30H36O12. Mole weight: 588.6. | |
| tert-Butyl 2-Amino-4-(4-methyl-1-piperazinyl)benzoate | tert-Butyl 2-Amino-4-(4-methyl-1-piperazinyl)benzoate. Synonyms: 2-amino-4-(4-methyl-1-piperazinyl)benzoic acid tert-butyl ester; tert-butyl 2-amino-4-(4-methylpiperazin-1-yl)benzoate. CAS No. 1034975-35-3. Molecular formula: C16H25N3O2. Mole weight: 291.39. | |
| Tetrachyrin | Tetrachyrin is a natural diterpenoid found in the herbs of Wedelia paludosa. Synonyms: (4R)-10-Hydroxy-9α-methyl-20-norkaur-16-en-18-oic acid 18,10-lactone. Grade: >95%. CAS No. 73483-88-2. Molecular formula: C20H28O2. Mole weight: 300.4. | |
| Tetradecyl Nicotinate | Tetradecyl Nicotinate can be combined with other drugs in the treatment of dermatological conditions. Synonyms: Myristyl nicotinate; 3-pyridinecarboxylic acid tetradecyl ester. Grade: 98%. CAS No. 273203-62-6. Molecular formula: C20H33NO2. Mole weight: 319.48. | |
| Tetrahydro-2H-thiopyran-4-carboxylic Acid 1,1-Dioxide | Tetrahydro-2H-thiopyran-4-carboxylic Acid 1,1-Dioxide (CAS# 64096-87-3) is a useful research chemical. Synonyms: 1,1-dioxo-4-thianecarboxylic acid; 1,1-dioxothiane-4-carboxylic acid. CAS No. 64096-87-3. Molecular formula: C6H10O4S. Mole weight: 178.21. | |
| TETRAHYDROALSTONINE | Tetrahydroalstonine may be extracted from the herbs of Uncaria rhynchophylla (Miq.) Miq. ex Havil. Raubasine and Tetrahydroalstonine preferentially block the pressor responses of post-synaptic alpha-adrenergic receptor activation due to endogenous and exogenous noradrenaline, respectively. Uses: Vasodilator agents. Synonyms: ALSTONINE; 20-alpha)-lph; 3,4,5,6-tetrahydro-alstonin; TETRAHYDROALSTONINE; methyl (19alpha,20alpha)-16,17-didehydro-19-methyloxayohimban-16-carboxylate; TETRAHYDROALSTONINE(RG); (20α)-16,17-Didehydro-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester; 3α,4,5,6-Tetrahydroalstonine. Grade: >98%. CAS No. 6474-90-4. Molecular formula: C21H24N2O3. Mole weight: 352.4. | |
| Tetrahydrocurcumin | Tetrahydrocurcumin is being studied for the treatment of cancer and dementia. Tetrahydrocurcumin has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress. Tetrahydrocurcumin is a natural functional whitening material, which is extracted from the rhizome of Curcuma longa L. It can effectively inhibit the generation of oxygen free radicals and remove the formed free radicals, and has obvious antioxidant effects, such as anti-aging of human skin, repairing, fading pigment, removing freckles, and so on. It is widely used in whitening, removing freckles, and antioxidant skin care products. It can also treat acne and reduce acne marks and pits. It has antibacterial, anti-inflammatory, antiallergenic, and analgesic effects, and can also prevent scars and fibrosis. Uses: Antioxidant. Synonyms: 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione; AS-KTC 004; HZIV 81-2; NSC 687845; Sabiwhite; Tetrahydrodiferuloylmethane. Grade: >98%. CAS No. 36062-04-1. Molecular formula: C21H24O6. Mole weight: 372.41. | |
| Tetrahydroxysqualene | Tetrahydroxysqualene isolated from the barks of Toxicodendron vernicifluum. It shows only modest cytotoxicity. Uses: Antimycobacterial activity. Synonyms: 1043629-23-7; (2E)-2-[(4E,8E,12E,16E)-4,8,13,17,21-pentamethyldocosa-4,8,12,16,20-pentaenylidene]propane-1,1,1,3-tetrol; ZINC95933324. Grade: 97.5%. CAS No. 1043629-23-7. Molecular formula: C30H50O4. Mole weight: 474.7. | |
| Tetrakis(4-bromophenyl)methane | Tetrakis(4-bromophenyl)methane can be used as a catalyst. Synonyms: Tetrakis(p-bromophenyl)methane. Grade: > 95.0 % (GC). CAS No. 105309-59-9. Molecular formula: C25H16Br4. Mole weight: 636.01. | |
| Tetrandrine | Tetrandrine is a bisbenylisoquinoline alkaloid isolated from the dried root of Stephenia tetrandra S Moore. Tetrandrine exhibits very broad pharmacological actions, including anti-tumor activity. The beneficial effects of tetrandrine on tumor cell cytotoxicity and radiosensitization, multidrug resistance, normal tissue radioprotection, and angiogenesis are most promising and deserve great attention. Tetrandrine has the potential either as a tumoricidal agent or as an adjunct to chemotherapy and radiotherapy. Uses: Nti-inflammatory, immunologic and antiallergenic. Synonyms: Isotetrandrine; Tetrandrin; Fanchinine; (+)-Tetrandrine; Sinomenine A. Grade: ≥ 98%. CAS No. 518-34-3. Molecular formula: C38H42N2O6. Mole weight: 622.762. | |
| Tetrazine PEG Thiol, MW 2k-5k | Tetrazine PEG derivatives are used to react with TCO (transcyclooctene) groups. Tetrazine PEG derivatives have excellent water solubility, possess fast kinetics and stability in aqueous buffer. Synonyms: Tetrazine-PEG-SH. | |
| Tetrazine-Ph-NHS ester | Tetrazine-Ph-NHS ester is a PROTAC linker, which is composed of alkyl chains. Tetrazine-Ph-NHS ester can be used to synthesize a range of PROTACs. Synonyms: Tetrazine-NHS ester. Grade: 95%. CAS No. 1616668-55-3. Molecular formula: C14H11N5O4. Mole weight: 313.27. | |
| Thalidomide-O-C7-acid | Thalidomide-O-C7-acid is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C7 alkyl linker with a terminal carboxylic acid, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. CAS No. 2169266-70-8. Molecular formula: C21H24N2O7. Mole weight: 416.42. | |
| Thalirugidine | Thalirugidine is an alkaloid isolated from the roots of Thalictrum foliolosum. Synonyms: (1S)-1-[[4-[5-[[(1S)-5-hydroxy-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-methoxyphenoxy]phenyl]methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-5-ol. Grade: 97.0%. CAS No. 64215-95-8. Molecular formula: C39H46N2O8. Mole weight: 670.803. | |
| Thalrugosaminine | Thalrugosaminine is a benzylisoquinoline alkaloid isolated from the roots of Thalictrum minus, which displays promising antibacterial, hypotensive and antimicrobial activity. Synonyms: (-)-Thalrugosaminine. Grade: 98.0%. CAS No. 22226-73-9. Molecular formula: C39H44N2O7. Mole weight: 652.788. | |
| Thevebioside | Thevebioside isolated from the herbs of Thevetia neriifolia. It is cardiac glycosides. Uses: Has cardiac action. Synonyms: (3β,5β)-3-{[6-Deoxy-4-O-(β-D-glucopyranosyl)-3-O-methyl-α-L-gluco pyranosyl]oxy}-14-hydroxycard-20(22)-enolide. Grade: 97%. CAS No. 114586-47-9. Molecular formula: C36H56O13. Mole weight: 696.8. | |
| Thevetin B | Thevetin A is a cardiac glycoside isolated from the herbs of Thevetia peruviana. Synonyms: 3β-[4-O-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]-6-deoxy-3-O-methyl-α-L-glucopyranosyloxy]-14β-hydroxy-5β-card-20(22)-enolide; Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-. Grade: 98%. CAS No. 27127-79-3. Molecular formula: C42H66O18. Mole weight: 858.96. | |
| Theviridoside | Theviridoside is a natural iridoid found in the leaves of Cerbera odollam, it has cytotoxicity. Uses: Cytotoxicity. Synonyms: (1S)-1α-(β-D-Glucopyranosyloxy)-1,4a,5,7aα-tetrahydro-4aα-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylic acid methyl ester. Grade: >98%. CAS No. 23407-76-3. Molecular formula: C17H24O11. Mole weight: 404.4. | |
| Thioxanthen-9-one | Thioxanthen-9-one is a photoinitiator. Synonyms: 9-thioxanthenone. Grade: 97 %. CAS No. 492-22-8. Molecular formula: C13H8OS. Mole weight: 212.27. | |
| (Thr17)-c-Jun (11-23) | (Thr17)-c-Jun (11-23) is a Plk1 substrate. Synonyms: H-Asp-Asp-Ala-Leu-Asn-Ala-Thr-Phe-Leu-Pro-Ser-Glu-Gly-OH; L-α-Aspartyl-L-α-aspartyl-L-alanyl-L-leucyl-L-asparaginyl-L-alanyl-L-threonyl-L-phenylalanyl-L-leucyl-L-prolyl-L-seryl-L-α-glutamylglycine. Grade: ≥95%. CAS No. 2243207-05-6. Molecular formula: C58H88N14O23. Mole weight: 1349.42. | |
| (Thr2)-Amyloid β-Protein (1-42) | This is a mutation very close to the APP β-secretase cleavage site. The pathogenicity of Aβ42 Icelandic mutation A2T is lower than the native sequence. The precursor APP A673T is the first variant of APP found to reduce the risk of Alzheimer's disease in humans. A2T also affects the cleavage of γ-secretase, and the mutant is an inefficient substrate in a cell-based enzyme assay. Synonyms: Amyloid β-Protein (1-42) lcelandic mutation; H-Asp-Thr-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grade: ≥95%. Molecular formula: C204H313N55O61S. Mole weight: 4544.13. | |
| (Thr506)-α-1,3-Glucosyltransferase (500-520) | (Thr506)-α-1,3-Glucosyltransferase (500-520) is a mAlg8 peptide sequence derived from α-1,3-Glucosyltransferase (A506T mutation) and contains an epitope ITYTWTRL binding to mouse MHC H-2Kb. ITYTWTRL is a tumor-specific mutant antigen in T3 MCA sarcomas. Synonyms: H-Ala-Val-Gly-Ile-Thr-Tyr-Thr-Trp-Thr-Arg-Leu-Tyr-Ala-Ser-Val-Leu-Thr-Gly-Ser-Leu-Val-OH. Grade: ≥95%. Molecular formula: C106H167N25O30. Mole weight: 2271.64. | |
| threo-1-C-Syringylglycerol | threo-1-C-Syringylglycerol is a chemical with possible inhibitory effects on pro-inflammatory cytokines production in LPS-stimulated bone marrow-derived dendritic cells which is constituent from Kandelia candel, the product is from the roots of Coix lachryma-jobi. Uses: Effects on pro-inflammatory cytokines production in lps-stimulated bone marrow-derived dendritic cells. Synonyms: (1R,2R)-rel-1-(4-Hydroxy-3,5-dimethoxyphenyl)-1,2,3-propanetriol; (R*,R*)-1-(4-Hydroxy-3,5-dimethoxyphenyl)-1,2,3-propanetriol. Grade: >95%. CAS No. 121748-11-6. Molecular formula: C11H16O6. Mole weight: 244.2. | |
| (Thr(PO3H2)231)-Tau Peptide (225-237) | Trans-cis-conversion of the pThr231-Pro232 motif has been observed in the early stages of Alzheimer's disease. Pin1 prevents the accumulation of the resulting pathogenic form of tau by reversing isomerization. Synonyms: Phosphorylated Thr231-Pro Tau; H-Lys-Val-Ala-Val-Val-Arg-Thr(PO3H2)-Pro-Pro-Lys-Ser-Pro-Ser-OH; L-Lysyl-L-valyl-L-alanyl-L-valyl-L-valyl-L-arginyl-[O-phosphono-L-threonyl]-L-prolyl-L-prolyl-L-lysyl-L-seryl-L-prolyl-L-serine. Grade: ≥95%. CAS No. 1670270-09-3. Molecular formula: C61H109N18O20P. Mole weight: 1445.60. | |
| Tilifodiolide | Tilifodiolide can be extracted from the herbs of Salvia tiliaefolia. Synonyms: Naphtho[1,2-c]furan-3(1H)-one,8-(2,5-dihydro-2-oxo-3-furanyl)-1-(3-furanyl)-6,7,8,9-tetrahydro-, (1R,8S)-; (1R,8S)-1α-(3-Furanyl)-6,7,8,9-tetrahydro-8α-[(2,5-dihydro-2-oxofuran)-3-yl]naphtho[1,2-c]furan-3(1H)-one. Grade: >98%. CAS No. 126724-95-6. Molecular formula: C20H16O5. Mole weight: 336.3. | |
| Tiliroside | Tiliroside, also called 6''-O-trans-p-Coumaroylastragalin, is a natural flavonoid found in the herbs of Agrimonia pilosa Ledeb. Tiliroside shows a hepatoprotective effect against D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced liver injury in mice. Tiliroside also exhibits anticarcinogenic, antioxidant, anti-inflammatory and anti-diabetic activities. Uses: Anticarcinogenic; antioxidant; anti-inflammatory; anti-diabetic. Synonyms: 6''-O-trans-p-Coumaroylastragalin. Grade: >98%. CAS No. 20316-62-5. Molecular formula: C30H26O13. Mole weight: 594.5. | |
| Timosaponin A-III | Timosaponin A3 is extracted from the rhizomes of Anemarrhena asphodeloides Bunge. Synonyms: Anemarsaponin A3; Filiferin B; (3β,5β,25S)-Spirostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; Timosaponin A III; Anemarsaponin A 3; Sarsasapogenin, 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; Sarsasapogenin-3-O-(2'-O-β-glucopyranosyl-β-galactopyranoside); Timosaponine A III; Xilingsaponin A; Zhi-mu saponin. Grade: >98%. CAS No. 41059-79-4. Molecular formula: C39H64O13. Mole weight: 740.92. | |
| Timosaponin B II | Timosaponin BII is extracted from the rhizomes of Anemarrhena asphodeloides Bunge. It has antioxidant, potential anti-dementia activity. It remarkably inhibited the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina. Synonyms: (25S)-26-(β-D-Glucopyranosyloxy)-3β-[(2-O-β-D-glucopyranosyl-β-D-galactopyranosyl)oxy]-5β-furostan-22-ol; (25S)-3β-[(2-O-β-D-Glucopyranosyl-β-D-galactopyranosyl)oxy]-26-(β-D-glucopyranosyloxy)-5β-furostane-22-ol. Grade: >98%. CAS No. 136656-07-0. Molecular formula: C45H76O19. Mole weight: 921.1. | |
| Tinosporol A | Tinosporol A, a constituent of Tinospora cordifolia, boasts anti-inflammatory and anticancer properties. Its effectiveness at thwarting the growth of cancer cells - leukemic and colon alike - is scientifically documented. Moreover, Tinosporol A has shown inhibitory capacities in the production of inflammatory cytokines, contributing to its potential as an anti-inflammatory agent. Grade: > 95%. CAS No. 2244777-12-4. Molecular formula: C21H26O8. Mole weight: 406.43. | |
| Tinosporoside A | Tinosporoside A is a natural compound found in Tinospora cordifolia. It exhibits potential in studying various diseases such as cancer, diabetes and liver disorders. Grade: > 95%. CAS No. 2244777-15-7. Molecular formula: C27H36O12. Mole weight: 552.57. | |
| TMC-58B | Aurantiamide, a natural alkaloid found in the herbs of Walsura yunnanensis, is used as significant anti-inflammatory and antinociceptive. it can serve as the natural compound for inhibiting cysteine proteinases, in particular, cathepsin L (3.4.22.15) and B (3.4.22.1) with IC50 of 12 microM and 49 microM, respectively. It may suppress the growth of malignant gliomas by blocking autophagic flux. Uses: Anti-neuroinflammatory; anti-inflammatory; antinociceptive. Synonyms: (S)-α-(Benzoylamino)-N-[(S)-1-(hydroxymethyl)-2-phenylethyl]benzenepropanamide. Grade: >95%. CAS No. 58115-31-4. Molecular formula: C25H26N2O3. Mole weight: 402.5. | |
| Toddalolactone | Toddalolactone usually can be isolated from the roots of Toddalia asiatica Lam. Uses: Anti-inflammatory/analgesic/anti-cancer. Synonyms: 6-(2,3-Dihydroxy-3-methylbutyl)-5,7-dimethoxy-2H-1-benzopyran-2-one; Toddaline; (+)-Toddalolactone; 6-[(2R)-2,3-dihydroxy-3-methyl-butyl]-5,7-dimethoxy-chromen-2-one; 6-[(2R)-2,3-dihydroxy-3-methylbutyl]-5,7-dimethoxychromen-2-one; 6-[(2R)-2,3-dihydroxy-3-methyl-butyl]-5,7-dimethoxy-coumarin. Grade: >98%. CAS No. 483-90-9. Molecular formula: C16H20O6. Mole weight: 308.33. | |
| Toddalosin | Toddalosin is a bicoumarin isolated from Toddalia asiatica. Synonyms: 8-[(1S,6R)-6-[(R)-(5,7-dimethoxy-2-oxochromen-8-yl)-hydroxymethyl]-3,5,5-trimethylcyclohex-2-en-1-yl]-5,7-dimethoxychromen-2-one. Grade: 98.0%. CAS No. 137182-37-7. Molecular formula: C32H34O9. Mole weight: 562.615. | |
| Toltrazuril | Toltrazuril can be used to treat poultry coccidiosis. Synonyms: Baycox; Toltrazurilo; Toltrazurilum. Grade: >98%. CAS No. 69004-03-1. Molecular formula: C18H14F3N3O4S. Mole weight: 425.38. | |
| Tomatine | Tomatine is a glycoalkaloid extracted from the fruits of Solanum lycopersicum. Synonyms: Lycopersicin; (3β,5α,22β,25S)-Spirosolan-3-yl O-β-D-glucopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→3)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside; α-Tomatine; NSC 234440; NSC 9223; TiterMax tomatine; Tomatine vaccine adjuvant. Grade: >98%. CAS No. 17406-45-0. Molecular formula: C50H83NO21. Mole weight: 1034.19. | |
| Tomentin | Tomentin, a natural plant coumarin which is isolated from the barks of Jatropha curcas, exhibits anti-inflammatory activity. Tomentin also can inhibit papain-like protease. Uses: Anti-inflammatory. Synonyms: 5-Hydroxy-6,7-dimethoxycoumarin. Grade: >98%. CAS No. 28449-62-9. Molecular formula: C11H10O5. Mole weight: 222.2. | |
| Toosendanin | Toosendanin is a natural diterpenoid compound found in the barks of Melia toosendan Sieb. et Zucc. Toosendanin shows hepatotoxicity and is also an effective insecticide for Ae. Synonyms: 24-Norchola-20,22-diene-4-carboxaldehyde,3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-,cyclic4,19-hemiacetal, [C(R),1α,3α,4β, 5α,7α,12α,13α,14β,15β,17α]-; Chuanliansu; 28-Deacetylsendanin; 12-AcetoxyaMoorastatin. Grade: >98%. CAS No. 58812-37-6. Molecular formula: C30H38O11. Mole weight: 574.62. | |
| Torachrysone | Torachrysone is a natural phenol isolated from the seeds of Cassia obtusifolia. Synonyms: 2-Acetyl-3-methyl-6-methoxynaphthalene-1,8-diol. Grade: >97%. CAS No. 22649-04-3. Molecular formula: C14H14O4. Mole weight: 246.3. | |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Synonyms: 7-Acetyl-8-hydroxy-3-methoxy-6-methyl-1-naphthyl β-D-glucopyranos ide. Grade: >98%. CAS No. 64032-49-1. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Tormentic acid | Tormentic acid is a terpenoid isolated from the herb of Potentilla tormentilla. It inhibits LPS-induced iNOS, COX-2, and TNF-α expression through inactivation of the nuclear factor-κb pathway in RAW 264.7 macrophages. Synonyms: Jacarandic acid; (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; 2α,19α-Dihydroxyursolic acid. Grade: >98%. CAS No. 13850-16-3. Molecular formula: C30H48O5. Mole weight: 488.709. | |
| Trachelosiaside | Trachelosiaside is isolated from the leaves of Trachelospermum lucidum (D. Don) Schum. Trachelosiaside shows moderate activity against lipoxygenase. Synonyms: Matairesinol 5-C-glucoside. Grade: 98.0%. CAS No. 106647-12-5. Molecular formula: C26H32O11. Mole weight: 520.52. | |
| (±)-trans-1,2-Diaminocyclohexane trityl resin | (±)-trans-1,2-Diaminocyclohexane trityl resin. | |
| trans-1-Amino-4-(hydroxymethyl)cyclohexane | Metabolites of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (Me CCNU). Synonyms: (4-aminocyclohexyl)methanol; (4-aminocyclohexyl)methanol. CAS No. 1467-84-1. Molecular formula: C7H15NO. Mole weight: 129.20. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(2-bromophenyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(2-bromophenyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(2-bromophenyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(2-bromophenyl)-OH; Boc-(±)-trans-4-(2-bromophenyl)pyrrolidine-3-carboxylic acid; (3R,4S)-4-(2-bromophenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. Grade: ≥ 99% by HPLC. CAS No. 1161787-74-1. Molecular formula: C16H20BrNO4. Mole weight: 370.24. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(2-chlorophenyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(2-chlorophenyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(2-chlorophenyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(2-chlorophenyl)-OH; (3S)-4-(2-chlorophenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. Grade: ≥ 95%. CAS No. 1212102-71-0. Molecular formula: C16H20ClNO4. Mole weight: 325.79. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(2-cyanophenyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(2-cyanophenyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(2-cyanophenyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(2-cyanophenyl)-OH; (3R,4S)-4-(2-cyanophenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid. Grade: ≥ 95%. CAS No. 1161787-84-3. Molecular formula: C17H20N2O4. Mole weight: 316.35. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(2-methoxyphenyl)pyrrolidine-3-carboxylic acid | Boc-(±)-trans-4-(2-methoxyphenyl)pyrrolidine-3-carboxylic Acid is a useful synthetic intermediate. Synonyms: Boc-(±)-trans-4-(2-methoxyphenyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(2-methoxyphenyl)-OH; (3R,4S)-1-(tert-Butoxycarbonyl)-4-(2-methoxyphenyl)pyrrolidine-3-carboxylic acid. Grade: ≥ 99% (HPLC). CAS No. 1217689-78-5. Molecular formula: C17H23NO5. Mole weight: 321.37. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(2-methylphenyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(2-methylphenyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(2-methylphenyl)pyrrolidine-3-carboxylic acid; (3R,4S)-4-(2-methylphenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid; Trans-1-Boc-4-o-tolylpyrrolidine-3-carboxylic acid; (3R,4S)-1-(tert-Butoxycarbonyl)-4-(o-tolyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(2-methylphenyl)-OH. Grade: ≥ 95%. CAS No. 957476-23-2. Molecular formula: C17H23NO4. Mole weight: 305.37. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(2-pyridinyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(2-pyridinyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(2-pyridinyl)pyrrolidine-3-carboxylic acid; BOC-(TRANS)-4-(2-PYRIDINYL)-PYRROLIDINE-3-CARBOXYLIC ACID; BOC-DL-TRANS-4-2-PYRIDINYLPYRROLIDINE-3-CARBOXYLIC ACID; Boc-trans-DL-β-Pro-4-(2-pyridinyl)-OH. Grade: ≥ 98% (HPLC). CAS No. 267876-09-5. Molecular formula: C15H20N2O4. Mole weight: 292.33. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(3-bromophenyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(3-bromophenyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(3-bromophenyl)pyrrolidine-3-carboxylic acid; Boc-trans-DL-β-Pro-4-(3-bromophenyl)-OH. Grade: ≥ 98% by HPLC. CAS No. 1161787-83-2. Molecular formula: C16H20BrNO4. Mole weight: 370.24. | |
| (±)-trans-1-(t-Butoxycarbonyl)-4-(3-chlorophenyl)pyrrolidine-3-carboxylic acid | (±)-trans-1-(t-Butoxycarbonyl)-4-(3-chlorophenyl)pyrrolidine-3-carboxylic acid. Synonyms: Boc-(±)-trans-4-(3-chlorophenyl)pyrrolidine-3-carboxylic acid; (3R,4S)-4-(3-Chlorophenyl)-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid; Boc-trans-DL-β-Pro-4-(3-chlorophenyl)-OH. Grade: ≥ 98% (HPLC). CAS No. 1217859-41-0. Molecular formula: C16H20ClNO4. Mole weight: 325.79. | |
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