BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| THPN | THPN is a Nur77 agonist. It binds to Nur77 receptor, resulting in autophagy in melanoma cell lines. Synonyms: 1-(3,4,5-Trihydroxyphenyl)-1-nonanone; 1-(2,4,6-Trihydroxyphenyl)-1-nonanone. Grades: ≥98% by HPLC. CAS No. 100079-26-3. Molecular formula: C15H22O4. Mole weight: 266.33. |  |
| Thrombin receptor agonist peptide trifluoroacetate salt | Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. Synonyms: TRAP-14. Grades: ≥95%. Molecular formula: C81H118N20O23·xCF3COOH. Mole weight: 1739.92. | |
| Thrombin receptor peptide ligand trifluoroacetate salt | Thrombin receptor peptide ligand acts as an antagonist of the thrombin receptor. It can inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide (TRAP) in vitro. Synonyms: AFLARAA. Grades: ≥95%. Molecular formula: C33H54N10O8·xCF3COOH. Mole weight: 718.84. | |
| Thymalfasin | Thymalfasin is an immunomodulating agent indicated as an adjuvant for influenza vaccine in elderly patients. Synonyms: Thymosin α1. Grades: 98%. CAS No. 69440-99-9. Molecular formula: C129H215N33O55. Mole weight: 3108.31. | |
| Thyroid Hormone Receptor Antagonist (1-850) | Thyroid hormone receptor antagonist (1-850) competitively blocks T3 binding to both TRα and TR&beta. Synonyms: 2-{2-[1-(4-nitrophenyl)-4-piperidinylidene]acetyl}-N-[3-(trifluoromethyl)phenyl]-1-hydrazinecarboxamide; 1-[[2-[1-(4-nitrophenyl)piperidin-4-ylidene]acetyl]amino]-3-[3-(trifluoromethyl)phenyl]urea; TR Antagonist, 1-850. Grades: ≥98%. CAS No. 251310-57-3. Molecular formula: C21H20F3N5O4. Mole weight: 463.4. | |
| Tiagabine | Tiagabine is a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. Synonyms: NO328; NO 328; NO-328. Grades: >98%. CAS No. 115103-54-3. Molecular formula: C20H25NO2S2. Mole weight: 375.55. | |
| Tiaramide hydrochloride | Tiaramide is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties. It is commonly used in the treatment of asthma. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 2(3H)-Benzothiazolone, 5-chloro-3-[2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl]-, hydrochloride (1:1); 1-Piperazineethanol, 4-[(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl]-, monohydrochloride; FK 1160; NSC 289337; NTA 194; RHC 2592; Solantal. Grades: ≥95%. CAS No. 35941-71-0. Molecular formula: C15H19Cl2N3O3S. Mole weight: 392.30. | |
| Ticagrelor | Ticagrelor is a platelet aggregation inhibitor and P2Y12 receptor antagonist. It has been used for the prevention of thrombotic events like stroke or heart attack in patients with acute coronary syndrome or myocardial infarction with ST elevation. Synonyms: Brilinta; Brilique; AZD-6140; AZD6140; AZD 6140; AR-C 126532XX; AR-C-126532XX; AR-C126532XX; Possia. Grades: ≥98%. CAS No. 274693-27-5. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57. | |
| Ticagrelor impurity 40 | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor Related Compound 40; Ticagrelor Impurity O; 2,2-(((3aR,3aR,4S,4S,6R,6aS,6R,6aS)-((5-amino-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))bis(ethan-1-ol). Grades: >95%. CAS No. 1882095-51-3. Molecular formula: C27H45N5O8S. Mole weight: 599.74. | |
| Ticagrelor Impurity A | Cas No. 1788033-05-5. | |
| Ticagrelor impurity G | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: (1S,2R,3S,4R)-4-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2,3-triol. Grades: >95%. CAS No. 220347-05-7. Molecular formula: C21H24F2N6O3S. Mole weight: 478.51. | |
| Ticagrelor Related Compound 16 | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor Impurity; 1,2-Cyclopentanediol, 3-[7-[[(1S,2R)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-; (1S,2S,3R,5S)-3-[7-[[(1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol; (1S,2S,3R,5S)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol. Grades: >98%. CAS No. 2096989-56-7. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57. | |
| Ticagrelor Related Compound 29 | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate. Grades: >95%. CAS No. 1265919-24-1. Molecular formula: C12H21NO5. Mole weight: 259.30. | |
| Ticagrelor Related Compound 75 | An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 4,6-dichloro-2-(propylthio)pyrimidine. CAS No. 1401318-10-2. Molecular formula: C7H8Cl2N2S. Mole weight: 223.12. | |
| Tie2 Inhibitor 7 | Tie2 Inhibitor 7 is a selective inhibitor of Tie2 kinase activity with Ki value of 1.3 μM. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with IC50 value of 0.3 μM. Synonyms: (S) -5- (4- ( ( (2- ( (1-Cyclohexylethyl) amino) -2-oxoethyl) ( (p-tolyloxy) carbonyl) amino) methyl) phenyl) nicotinic acid; 5-[4-[[[2-[[ (1S) -1-Cyclohexylethyl]amino]-2-oxoethyl]- (4-methylphenoxy) carbonylamino]methyl]phenyl]pyridine-3-carboxylic acid. Grades: ≥95%. CAS No. 1020412-97-8. Molecular formula: C31H35N3O5. Mole weight: 529.6. | |
| Tilivapram | Tilivapram, a pyridine derivative, has been found to be a phosphodiesterase IV inhibitor that could probably be used in studying its bioactivities in sorts of areas. Synonyms: Tilivapram; UNII-B5983P6VWM; Tilivapram [INN]; B5983P6VWM; SCHEMBL1433277; 4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-hydroxypyridin-4-ylidene)-5-methoxypyridine-2-carboxamide. Grades: 98%. CAS No. 166741-91-9. Molecular formula: C16H15Cl2N3O4. Mole weight: 384.21. | |
| Tilorone dihydrochloride | Tilorone dihydrochloride, as a broad-spectrum, orally active antiviral agent, is an orally active interferon inducer. Synonyms: 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one;dihydrochloride. Grades: ≥ 98 %. CAS No. 27591-69-1. Molecular formula: C25H34N2O3 · 2HCl. Mole weight: 483.47. | |
| Tiludronic acid disodium salt | The disodium salt form of Tiludronic acid which has been found to be a biphosphonate bone resorption inhibitor and could be used against osteitis deformans. Uses: A biphosphonate bone resorption inhibitor. Synonyms: TILUDRONATE DISODIUM; Skelid; Tiludronic acid disodium salt; 149845-07-8; UNII-BH6M93CIA0; Tiludronate disodium [USAN] ; disodium;[(4-chlorophenyl)sulfanyl-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate. Grades: 98%. CAS No. 149845-07-8. Molecular formula: C7H7ClNa2O6P2S. Mole weight: 362.57. | |
| Timapiprant | Timapiprant is a potent and selective D prostanoid receptor 2 (DP2; CRTH2) antagonist. It effectively improves lung function and symptoms in patients with atopic eosinophilic asthma. It was shown to reduce both nasal and eye symptoms in allergic subjects exposed to grass pollen. Synonyms: OC-000459; OC 000459; OC000459; 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid. CAS No. 851723-84-7. Molecular formula: C21H17FN2O2. Mole weight: 348.37. | |
| Timapiprant sodium | Timapiprant is a potent and selective D prostanoid receptor 2 (DP2; CRTH2) antagonist. It effectively improves lung function and symptoms in patients with atopic eosinophilic asthma. It was shown to reduce both nasal and eye symptoms in allergic subjects exposed to grass pollen. Synonyms: OC-000459 sodium; OC 000459 sodium; OC000459 sodium; sodium 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetate. CAS No. 950688-14-9. Molecular formula: C21H16FN2NaO2. Mole weight: 370.35. | |
| Timosaponin A1 | Timosaponin A1 a coprostane type steroidal saponin isolated from Rhizoma Anemarrhenae which is the dry rootstock of Anemarrhenae asphodeloides Bunge (Liliaceae) dug in spring and fall. The rhizome of Anemarrhena asphodeloides Bunge (Liliaceae), has been used for a long time in traditional Chinese medicine with anti-diabetic activity anti-platelet aggregation activity and diuretic activity. Synonyms: (3β,5β,25S)-Spirostan-3-yl β-D-galactopyranoside; β-D-Galactopyranoside, (3β,?5β,?25S)?-spirostan-3-yl; Sarsasapogenin, β-D-galactopyranoside (7CI). Grades: > 98%. CAS No. 68422-00-4. Molecular formula: C33H54O8. Mole weight: 578.78. | |
| Timsaponin C | The rhizomes of Anemarrhena asphodeloides Bunge. Synonyms: Timsaponin C. Grades: >98%. CAS No. 185432-00-2. Molecular formula: C45H74O18. Mole weight: 903.1. | |
| Tinyatoxin | Tinyatoxin is a neurotoxin, acting via vanilloid receptors of sensory nerves. Synonyms: Tinyatoxin; Daphnetoxin, 6,7-deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)-, 20-(4-hydroxybenzeneacetate); [2-benzyl-6a-hydroxy-8,10-dimethyl-7-oxo-11a-(prop-1-en-2-yl)-3a,6,6a,7,9a,10,11,11a-octahydro-3bH-2,9b-epoxyazuleno[4',5':5,6]benzo[1,2-d][1,3]dioxol-5-yl]methyl (4-hydroxyphenyl)acetate; [(3aR,3bS,6aR,9aR,9bR,10R,11aR)-2-benzyl-6a-hydroxy-8,10-dimethyl-7-oxo-11a-(prop-1-en-2-yl)-3a,6,6a,7,9a,10,11,11a-octahydro-3bH-2,9b-epoxyazuleno[4',5':5,6]benzo[1,2-d][1,3]dioxol-5-yl]methyl (4-hydroxyphenyl)acetate. CAS No. 58821-95-7. Molecular formula: C36H38O8. Mole weight: 598.68. | |
| Tirasemtiv | Tirasemtiv is a a small-molecule fast-skeletal-troponin activator, which is being developed as a potential treatment for diseases and conditions associated with aging, muscle weakness and wasting or neuromuscular dysfunction. Synonyms: CK2017357; CK-2017357; CK 2017357; Tirasemtiv. Grades: >98%. CAS No. 1005491-05-3. Molecular formula: C12H14N4O. Mole weight: 230.27. | |
| Tirofiban | Tirofiban (MK-383, Aggrastat) is a nonpeptide derivative of tyrosine that selectively inhibits the GP-IIb/IIIa receptor, with minimal effects on the ?vβ3 vitronectin receptor. Uses: Antithrombotic; in treatment of unstable angina. Synonyms: Tirofiban; MK383; MK-383; MK 383. Grades: >98%. CAS No. 144494-65-5. Molecular formula: C22H36N2O5S. Mole weight: 440.6. | |
| Tixocortol Pivalate | Tixocortol Pivalate is a corticosteroid showing topical anti-inflammatory properties. It is marketed under the brand name Pivalone. Synonyms: Pivalone; Tixocortol 21-pivalate. Grades: >95%. CAS No. 55560-96-8. Molecular formula: C26H38O5S. Mole weight: 462.645. | |
| Tm5441 | TM5441 is a plasminogen activator inhibitor-1 (PAI-1) that inhibits some tumor cell lines (IC50 = 9.7 ~ 60.3 μM). Studies indicated that it could be used to treat high-fat diet-induced obesity and adipocyte injury in mice. Uses: Tm5441 is a plasminogen activator inhibitor-1 (pai-1). Synonyms: TM-5441; TM 5441; TM5441; BMS-790052; BMS-790052; BMS790052; EBP 883; EBP-883; EBP883. 5-chloro-2-(2-(2-((3-(furan-3-yl)phenyl)amino)-2-oxoethoxy)acetamido)benzoic acid. CAS No. 1190221-43-2. Molecular formula: C21H17ClN2O6. Mole weight: 428.825. | |
| TMC-205 | TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines, activated the transcriptional activity in a manner dependent on the presence of the enhancer element of SV40 in its promoter region. Uses: Transcriptional up-regulator. Synonyms: TMC-205; TMC 205; TMC205. 6-(3-methylbuta-1,3-dienyl)-1H-indole-3-carboxylic acid. Grades: ≥98%. CAS No. 403646-00-4. Molecular formula: C14H13NO2. Mole weight: 227.26. | |
| TM N1324 | TM N1324 is an orally bioavailable, potent and selective GPR39 agonist. It inhibits the release of ghrelin and somatostatin from primary gastric mucosa cells in vitro. Synonyms: 4-(2-Chloro-4-fluorophenyl)-1,4,5,7-tetrahydro-3-methyl-1-(9H-purin-6-yl)-6H-pyrazolo[3,4-b]pyridin-6-one. Grades: ≥98% by HPLC. CAS No. 1144477-35-9. Molecular formula: C18H13ClFN7O. Mole weight: 397.79. | |
| TMN 355 | TMN 355 is a potent cyclophilin A inhibitor (IC50 = 1.52 nM), displaying 27-fold potency against cyclosporin A. Synonyms: TMN 355; TMN355; TMN-355; 2-Chloro-N-[(9H-fluoren-9-ylamino)carbonyl]-6-fluorobenzamide. Grades: ≥98% by HPLC. CAS No. 1186372-20-2. Molecular formula: C21H14ClFN2O2. Mole weight: 380.8. | |
| TMP-153 | TMP-153 is an Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 values of 5-10 nM in various animals. It inhibits cholesterol esterification both in human colonic adenocarcinoma cells, LS180, and in human hepatoma cells, HepG2 (IC50 = 150 nM and 330 nM, respectively). Synonyms: N-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea; 1-[4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea. Grades: ≥95%. CAS No. 128831-46-9. Molecular formula: C24H18ClF2N3O. Mole weight: 437.9. | |
| TMP269 | TMP269 is a highly potent, selective and cell-permeable class IIa HDAC inhibitor with IC50 values of 126 nM, 80 nM, 36 nM and 19 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively. Synonyms: TMP269; TMP 269; TMP-269; N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide. Grades: 98%. CAS No. 1314890-29-3. Molecular formula: C25H21F3N4O3S. Mole weight: 514.523. | |
| TMPA | TMPA is an antagonist of nuclear receptor Nur77 (Kd = 1.45 ± 0.35 μM) and LKB1 interaction. Synonyms: ethyl 2-(2,3,4-trimethoxy-6-octanoylphenyl)acetate; ethyl 2-(2,3,4-trimethoxy-6-(1-octanoyl)phenyl)acetate. CAS No. 1258275-73-8. Molecular formula: C21H32O6. Mole weight: 380.48. | |
| TMPyP4 tosylate | TMPyP4 tosylate is a cationic porphyrin. TMPyP4 stacks with G tetrads to stabilize quadruplex DNA, and inhibits telomerase activity (IC50 ≤ 50 μM). TMPyP4 inhibits cell proliferation and induces apoptosis in three myeloma cell lines. Synonyms: 5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetra(p-toluenesulfonate); Tmpyp tetratosylate. Grades: ≥95% by HPLC. CAS No. 36951-72-1. Molecular formula: C72H66N8O12S4. Mole weight: 1363.6. | |
| TNF-α (10-36), human | TNF-α (10-36), human is a peptide of human TNF-&alpha. Synonyms: Asp-Lys-Pro-Val-Ala-His-Val-Val-Ala-Asn-Pro-Gln-Ala-Glu-Gly-Gln-Leu-Gln-Trp-Leu-Asn-Arg-Arg-Ala-Asn-Ala-Leu; L-Leucine, L-α-aspartyl-L-lysyl-L-prolyl-L-valyl-L-alanyl-L-histidyl-L-valyl-L-valyl-L-alanyl-L-asparaginyl-L-prolyl-L-glutaminyl-L-alanyl-L-α-glutamylglycyl-L-glutaminyl-L-leucyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-asparaginyl-L-arginyl-L-arginyl-L-alanyl-L-asparaginyl-L-alanyl-; tumor necrosis factor-alpha fragment 10-36 human. Grades: >95%. CAS No. 144796-70-3. Molecular formula: C131H211N43O38. Mole weight: 2996.34. | |
| TNF-α Antagonist | TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex, thus preventing ligand interaction with the receptor. Synonyms: W9; H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH (Disulfide bridge: Cys2-Cys8); L-tyrosyl-L-cysteinyl-L-tryptophyl-L-seryl-L-glutaminyl-L-tyrosyl-L-leucyl-L-cysteinyl-L-tyrosine (2->8)-disulfide; WP9QY; N-{[(4R,7S,10S,13S,16S,19S,22R)-13-(3-Amino-3-oxopropyl)-10-(4-hydroxybenzyl)-16-(hydroxymethyl)-19-(1H-indol-3-ylmethyl)-7-isobutyl-6,9,12,15,18,21-hexaoxo-22-(L-tyrosylamino)-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]carbonyl}-L-tyrosine. Grades: ≥95%. CAS No. 199999-60-5. Molecular formula: C58H71N11O15S2. Mole weight: 1226.38. | |
| TNKS656 | TNKS656, also known as NVP-TNKS656, is a potent and orally active Tankyrase Inhibitor. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency, TNKS656 is well suited for further in vivo validation studies. Synonyms: NVP-TNKS656; TNKS-656. Grades: 98%. CAS No. 1419949-20-4. Molecular formula: C27H34N4O5. Mole weight: 494.592. | |
| TNP | TNP is a reversible and cell-permeable inhibitor of inositol hexakisphosphate kinase (IP6K) (IC50 = 0.47 μM for inhibition of InsP7 formation) and inositol 1,4,5-trisphosphate 3-kinase (IP3K) (IC50 = 10.2 μM). Synonyms: N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; IP3K Inhibitor; Inositol-1,4,5-trisphosphate 3-Kinase Inhibitor. Grades: ≥97% by HPLC. CAS No. 519178-28-0. Molecular formula: C20H16F3N7O2. Mole weight: 443.38. | |
| TNP-470 | TNP-470 is an analog of fumagillin, an antimicrobial agent isolated from the fungus Aspergillus fumigatus. TNP-470 was shown to inhibit angiogenesis, and irreversibly suppress methionine aminopeptidase-2 (MetAP2). Uses: Angiogenesis inhibitors. Synonyms: AGM-1470; O-(Chloroacetyl-carbamoyl) Fumagillol; NSC 642492. Grades: ≥98%. CAS No. 129298-91-5. Molecular formula: C19H28ClNO6. Mole weight: 401.9. | |
| TOFA | TOFA is a cell-permeable, potent, reversible, and competitive allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). It inhibits the fatty acid biosynthesis by blocking the synthesis of malonyl-CoA. Uses: Hypolipidemic agents. Synonyms: 5-tetradecoxyfuran-2-carboxylic acid; 5-(tetradecyloxy)-2-furancarboxylic acid; 5-(tetradecyloxy)-2-furoic acid; RMI 14514; RMI-14514. CAS No. 54857-86-2. Molecular formula: C19H32O4. Mole weight: 324.45. | |
| Tofisopam | Tofisopam, a 2,3-benzodiazepine, has depressant effects at high doses in several different animal test procedures. Tofisopam has been shown to enhance the anticonvulsant action of classical 1,4-benzodiazepines such as diazepam. Synonyms: EGYT-341; EGYT 341; EGYT341; SERIEL; TOFISOPAM; 7,8-DIMETHOXY-1-(3,4-DIMETHOXYPHENYL)-5-ETHYL-4-METHYL-5H-2,3-BENZODIAZEPINE; EGYT 341; 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-2,3-benzodiazepine; 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5h-3-benzodiazepine. Grades: >98%. CAS No. 22345-47-7. Molecular formula: C22H26N2O4. Mole weight: 382.45. | |
| Tolazamide | Tolazamide, a sulphonylurea derivative, could be a hypoglycemic agent which is commonly used in Type 2 diabetes. Uses: Tolazamide could be a hypoglycemic agent which is commonly used in type 2 diabetes. Synonyms: 1-(hexahydro-1-azepinyl)-3-p-tolylsulfonylurea; 1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)-ure; 1-(hexahydro-1h-azepin-1-yl)-3-(p-tolylsulfonyl)urea; 4-(p-tolylsulfonyl)-1, 1-hexamethylenesemicarbazide; diabewas; n-(((hexahydro-1h-azepin-1-yl)-amino)carb. Grades: 98%. CAS No. 1156-19-0. Molecular formula: C14H21N3O3S. Mole weight: 311.39. | |
| Tolterodine Tartrate | Tolterodine has a high affinity and specificity for muscarinic receptors in vitro and it exhibits selectivity for the urinary bladder over salivary glands in vivo. Uses: Urological agents. Synonyms: PNU-200583E. Grades: >98%. CAS No. 124937-52-6. Molecular formula: C22H31NO.C4H6O6. Mole weight: 475.57. | |
| tolycaine | Tolycaine is an amide local anaesthetic used for dental injection. Synonyms: Baycain; Benzoic acid, 2-[[(diethylamino)acetyl]amino]-3-methyl-, methyl ester. Grades: 95%. CAS No. 3686-58-6. Molecular formula: C15H22N2O3. Mole weight: 278.35. | |
| Tomicorat | Tomicorat is used as an anti-inflammatory agent. Uses: Tomicorat is used as an anti-inflammatory agent. Synonyms: 4-(5-((5-Fluoro-2-methylphenoxy)methyl)-2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)-3-methoxyphenyl furan-2-carboxylate. Grades: >98 %. CAS No. 1027099-03-1. Molecular formula: C32H30FNO5. Mole weight: 527.59. | |
| Tonapofylline | Tonapofylline, a selective adenosine-1 receptor antagonist, has natriuretic effects and is able to maintain renal function, which can be beneficial to patients with congestive heart failure. Uses: Adenosine a1 receptor antagonists; adenosine a2b receptor antagonists. Synonyms: BG9928; BG-9928; BG 9928; Tonapofylline.3-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)bicyclo[2.2.2]octan-1-yl)propanoic acid. Grades: ≥98%. CAS No. 340021-17-2. Molecular formula: C22H32N4O4. Mole weight: 416.24. | |
| Tosylglycolic Acid | Tosylglycolic Acid is an intermediate of Cefmetazole. Synonyms: 2-[[(4-Methylphenyl)sulfonyl]oxy]acetic Acid. CAS No. 39794-77-9. Molecular formula: C9H10O5S. Mole weight: 230.24. | |
| Tp3654 | Tp3654 is an inhibitor of Pim-1 and Pim-3 that has the potential to treat prostate cancer, acute myeloid leukemia, multiple sclerosis and psoriasis. Uses: Tp3654 is an inhibitor of pim-1 and pim-3. Synonyms: TP-3654; TP3654; TP 3654; SCHEMBL102560; CS-6293; HY-101126; CS 6293; HY 101126; CS6293; HY101126; 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol. Grades: ≥98%. CAS No. 1361951-15-6. Molecular formula: C22H25F3N4O. Mole weight: 418.464. | |
| TP 472N | TP 472N is a negative control for TP 472. TP 472N is inactive against other bromodomains (>20 μM against BRD9). Synonyms: TP 472N; TP472N; TP-472N; 1- (8- (2- (Cyclopropylmethoxy) phenyl) pyrrolo[1, 2-a]pyrimidin-6-yl) ethanone. Grades: ≥98% by HPLC. CAS No. 2080306-24-5. Molecular formula: C19H18N2O2. Mole weight: 306.36. | |
| TPC-144 | TPC-144 is a novel and selective LSD1 inhibitor potentially used for the treatment of acute myeloid leukemia (AML) and small cell lung cancer (SCLC). TPC-144 reversibly inhibited LSD1 in a histone peptide-competitive manner not forming a covalent adduct with FAD. Uses: The potential treatment of aml and sclc. Synonyms: TPC-144; TPC144; TPC 144; 5'-((1R,3r,5S)-3-amino-8-azabicyclo[3.2.1]octane-8-carbonyl)-2'',3-difluoro-4''-(2-hydroxy-2-methylpropyl)-[1,1':2',1''-terphenyl]-4-carbonitrile. CAS No. 2098621-17-9. Molecular formula: C31H31F2N3O2. Mole weight: 515.6048. | |
| TPI-1 | TPI-1 selectively increased SHP-1 phospho-substrates (pLck-pY394, pZap70, and pSlp76) in Jurkat T cells but had little effects on pERK1/2 or pLck-pY505 regulated by phosphatases SHP-2 or CD45, respectively. Synonyms: 2-(2,5-dichlorophenyl)cyclohexa-2,5-diene-1,4-dione; 2-(2,5-dichlorophenyl)cyclohexa-2,5-diene-1,4-dione; 2-(2',5'-dichlorophenyl)-1,4-benzoquinone; CBMicro_042121; TPI-1; TPI 1; TPI1; Tyrosine Phosphatase Inhibitor 1. CAS No. 79756-69-7. Molecular formula: C12H6Cl2O2. Mole weight: 253.08. | |
| TPPU | TTPU is a soluble epoxide hydrolase inhibitor (sEHI) (IC50 = 37, 2.8 nM and 3.7 nM for monkey, mouse and human sEH, respectively) with anti-inflammatory, anti-hypertensive, neuroprotective, and cardioprotective effects. Synonyms: 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea. CAS No. 1222780-33-7. Molecular formula: C16H20F3N3O3. Mole weight: 359.34. | |
| TPT-260 | TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base form. Synonyms: TPU-260; TPU 260; TPU260. Grades: >98%. CAS No. 769856-81-7. Molecular formula: C8H12N4S3. Mole weight: 260.4. | |
| TPY-5628 | TPY-5628, a pyrrole derivative, has been found to be commonly used in sorts of chemical areas like anticancer drugs as an significant intermediate. Synonyms: TPY-5628; TPY 5628; TPY5628. 5,5'-[(3,4-DIETHYL-1H-PYRROLE-2,5-DIYL)BIS(METHYLENE)]BIS[4-(3-HYDROXYPROPYL)-3-METHYL-1H-PYRROLE-2-CARBOXALDEHYDE]; AGN-PC-004ZVA; SCHEMBL4107546; CTK4C6172; DTXSID00459675. Grades: 98%. CAS No. 149365-62-8. Molecular formula: C28H39N3O4. Mole weight: 481.64. | |
| TR-14035 | TR14035 blocked the binding of human alpha(4)beta(7) to an (125)I-MAdCAM-Ig fusion protein with IC(50) values of 0.75 nM. TR14035 blocked binding of human alpha(4)beta(7)-expressing RPMI-8866 cells or murine mesenteric lymph node lymphocytes to MAdCAM-Ig with IC(50) values of 0.1 microM. TR14035 blocked adhesion to HEVs [ED(50) of 0.01-0.1 mpk i.v.]. TR-14035 was taken up by rat and human hepatocytes by an apparently single saturable mechanism with K(m) of 6.7 and 2.1 microM, respectively, and taurocholate and digoxin reduced this uptake. Synonyms: TR 14035; TR14035; MDK-1191; MDK1191; MDK 1191; SB683698; SB 683698; SB-683698; QJ-2620; TR-14035. Grades: >98%. CAS No. 232271-19-1. Molecular formula: C24H21Cl2NO5. Mole weight: 474.33. | |
| Trabectedin | Trabectedin is an antitumor drug. Synonyms: Ecteinascidin; Yondelis; Ecteinascidin 743; ET-743; ET743; ET 743. Grades: 98%. CAS No. 114899-77-3. Molecular formula: C39H43N3O11S. Mole weight: 761.84. | |
| Trametinib | A MEK inhibitor that suppresses MEK1 and MEK2 with IC50 of 0.92 and 1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. It has been approved by FDA, in combination with Tafilnar, for the treatment of metastatic anaplastic thyroid cancer (ATC) with BRAF V600E mutation. Synonyms: GSK-1120212; GSK 1120212; GSK1120212; JTP74057; JTP 74057; JTP-74057; Mekinist. Grades: ≥98%. CAS No. 871700-17-3. Molecular formula: C26H23FIN5O4. Mole weight: 615.39. | |
| Trandolapril | Trandolapril is an angiotensin converting enzyme (ACE) inhibitor. It has a longer biological half-life and a high degree of lipophilicity than others. It is used to treat high blood pressure. It acts by competitive inhibition of ACE, which is a key enzyme in the renin-angiotensin system and plays an important role in regulating blood pressure. lt inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2. It is marketed by Abbott Laboratories under the brand name Mavik. It has been listed. Uses: Trandolapril is used to treat high blood pressure. Synonyms: RU 44570; (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] hexahydro-2-indolinecarboxylic acid 1-ethyl ester. Grades: >98 %. CAS No. 87679-37-6. Molecular formula: C24H34N2O5. Mole weight: 430.53. | |
| trans-2-Butene-1,4-diol | trans-2-Butene-1,4-diol is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). Synonyms: 2-Butene-1,4-diol, (2E)-; (2E)-2-Butene-1,4-diol; 2-Butene-1,4-diol, (E)-; 2-Butene-1,4-diol, trans-; (2E)-But-2-ene-1,4-diol; (E)-2-Butene-1,4-diol; Penitricin C; trans-2-Buten-1,4-diol. Grades: ≥95%. CAS No. 821-11-4. Molecular formula: C4H8O2. Mole weight: 88.11. | |
| trans-3-Hexenoyl-CoA sodium salt | trans-3-Hexenoyl-CoA sodium salt is an imperative biochemical compound, exerting a pivotal influence on fatty acid metabolism and participates in myriad biochemical processes. Predominantly employed in investigations and analyses associated with lipid metabolism, this product additionally finds utility in the fabrication of pharmaceuticals aimed at studying metabolic ailments including diabetes and obesity. Synonyms: trans-3-Hexenoyl-CoA (sodium salt). Molecular formula: C27H44N7O17P3S.xNa. Mole weight: 863.7 (free acid). | |
| trans-4,5-Difluoroethylenecarbonate | trans-4,5-Difluoroethylenecarbonate (CAS# 311810-76-1 ) is a useful research chemical. Synonyms: 4alpha,5beta-Difluoro-1,3-dioxolane-2-one; 1,3-Dioxolan-2-one, 4,5-difluoro-, (4R,5R)-rel-; rel-(4R,5R)-4,5-difluoro-1,3-dioxolan-2-one; trans-4,5-difluoro-1,3-dioxolan-2-one; trans-difluoroethylene carbonate. Grades: 98 %. CAS No. 311810-76-1. Molecular formula: C3H2F2O3. Mole weight: 124.04. | |
| trans-4-Butylcyclohexanol | Trans-4-Butylcyclohexanol, a vital compound in pharmaceutical and agrochemical industries, serves as a key intermediate in the synthesis of a wide range of organic compounds, including amides, esters, and ketones. Notably, its ability to serve as a starting material in the preparation of drug substances and biochemicals highlights its paramount importance. Its versatility and functional properties make Trans-4-Butylcyclohexanol an indispensable component in the chemical research of life-changing drugs and biochemical products. Synonyms: 4-Butylcyclohexanol. Grades: 95%. CAS No. 67590-13-0. Molecular formula: C10H20O. Mole weight: 156.26. | |
| trans-4-Hydroxycrotonic acid | trans-4-Hydroxycrotonic acid has high affinity for the γ-hydroxybutyric acid (GHB) receptor. It may be an endogenous ligand. Synonyms: trans-4-Hydroxy-2-butenoic acid. Grades: ≥99% by HPLC. CAS No. 24587-49-3. Molecular formula: C4H6O3. Mole weight: 102.09. | |
| trans-4-Pentylcyclohexanecarboxylic acid | trans-4-Pentylcyclohexanecarboxylic acid is a useful research chemical. Synonyms: 4-Pentylcyclohexanecarboxylic acid. Grades: 95 %. CAS No. 38289-29-1. Molecular formula: C12H22O2. Mole weight: 198.30. | |
| trans-4- (Trifluoromethyl) cyclohexanecarboxylic acid | A cyclic haloalkyl substituted carboxylic acid used in the preparation of antiviral agents. Synonyms: 4-(trifluoromethyl)cyclohexane-1-carboxylic acid. Grades: 95 %. CAS No. 133261-33-3. Molecular formula: C8H11F3O2. Mole weight: 196.17. | |
| trans-AUCB | Trans-AUCB is a potent inhibitor of sEH with IC50 value of 0.5 nM. It exhibits anti-inflammatory, anti-hypertensive, anti-tumor and cardioprotective activities. Synonyms: 4-[4- (1-adamantylcarbamoylamino) cyclohexyl]oxybenzoic acid. Grades: ≥90%. CAS No. 885012-33-9. Molecular formula: C24H32N2O4. Mole weight: 412.5. | |
| trans-beta-Farnesene | (E)-β-Farnesene is a naturally volatile sesquiterpene hydrocarbon found in Phlomis aurea Decne essential oil, Nepeta nepetella and Eupatorium capillifolium. It can be used as a feeding stimulant for sandfly Lutzomyia longipalpis. Synonyms: (E)-β-Farnesene; β-Farnesene; (6E)-7,11-Dimethyl-3-methylene-1,6,10-dodecatriene; (E)-7,11-Dimethyl-3-methylene-1,6,10-dodecatriene; trans-7,11-Dimethyl-3-methylene-1,6,10-dodecatriene. Grades: ≥95%. CAS No. 18794-84-8. Molecular formula: C15H24. Mole weight: 204.35. | |
| trans-Clomiphene Citrate | Enclomiphene citrateis a non-steroidal estrogen receptor antagonist. It can be used for secondary hypogonadism in overweight men wishing to restore normal testicular function. Uses: Restore testicular function. Synonyms: 2-[4-[(1E)-2-Chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate; (E)-Clomiphene Citrate; Clomiphene B Citrate; Enclomid; Enclomiphene Citrate; trans-Clomiphene Citrate; 15690-57-0 (free). Grades: 98%. CAS No. 7599-79-3. Molecular formula: C32H36ClNO8. Mole weight: 598.08. | |
| Transdermal Peptide | TD-1 binds to Na+/K+-ATPase beta-subunit (ATP1B1) and interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. Synonyms: Transdermal Peptide 1. Grades: 98%. CAS No. 918629-48-8. Molecular formula: C40H66N14O16S2. Mole weight: 1063.17. | |
| Transforming Growth Factor | Transforming Growth Factor is classified as two polypeptide growth factors, TGFα and TGF&beta. TGFα is a peptide as a member of epidermal growth factor (EGF). TGFβ is a cytokine including three mammalian isoforms TGF-β1, TGF-β2, TGF-β3. TGFβ complex that combines with other factors binds to TGF-β receptors. Synonyms: TGF; tumor growth factor. | |
Our database is helping our users find suppliers everyday.
