BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Spantide I | Spantide I is a selective NK1 receptor antagonist (Ki = 230, 8150 and > 10000 nM for rat NK1, NK2 and NK3 receptors, respectively). Uses: Analgesics. Synonyms: [D-Arg1, D-Trp7,9, Leu11]-Substance P. CAS No. 91224-37-2. Molecular formula: C75H108N20O13. Mole weight: 1497.79. |  |
| Spartalizumab | Spartalizumab is a humanized anti-PD-1 IgG4 antibody under the development of melanoma treatment. Synonyms: PDR001. CAS No. 1935694-88-4. | |
| Sparteine | Sparteine is a natural alkaloid extracted from scotch broom. It inhibits mAChR M2 and M4, and displays anticonvulsant effects. It also inhibits nAChR in the neurons. Synonyms: 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7S,7aR,14S,14aS)-; (7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine; 7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, [7S-(7α, 7aα, 14α, 14aβ)]-; (-)-Sparteine; 6β,7α,9α,11α-Pachycarpine; L-(-)-Sparteine; L-Sparteine; l-Sparteine; Lupinidin; Lupinidine; Spartein. Grades: ≥98%. CAS No. 90-39-1. Molecular formula: C15H26N2. Mole weight: 234.38. | |
| SPD 304 | SPD 304 a cell-permeable inhibitor of tumor necrosis factor-α (TNFα, IC50 = 22 μM), which is a modulator of inflammation conditions such as rheumatoid arthritis, toxic shock, and sepsis. SPD 304 binids to TNFα trimer and promotes accelerated displacement of a single subunit to rapidly inactivate the cytokine. It inhibits TNF-α-induced IkB-α depletion in HeLa cells (IC50 = 4.6 μM). Uses: Anti-inflammatory agent. Synonyms: SPD-304, SPD 304, SPD304. 6, 7-dimethyl-3- [ [methyl- [2- [methyl- [ [1- [3- (trifluoromethyl) phenyl] indol-3-yl] methyl] amino] ethyl] amino] methyl] chromen-4-one; CAY10500. Grades: 99%. CAS No. 869998-49-2. Molecular formula: C32H32F3N3O2.2HCl. Mole weight: 620.53. | |
| Spexin | Spexin is an endogenous satiety-inducing peptide and a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 = 45.7 and 112.2 nM, respectively), displaying no significant activity at galanin receptor 1. Spexin inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. It exhibits anxiolytic effects in vivo. Synonyms: SPX; NPQ (human, mouse, bovine); H-Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2; L-asparagyl-L-tryptophyl-L-threonyl-L-prolyl-L-glutaminyl-L-alanyl-L-methionyl-L-leucyl-L-tyrosyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-glutaminamide; Neuropeptide Q; Spexin (36-49) amidated. Grades: ≥95%. CAS No. 1370290-58-6. Molecular formula: C74H114N20O19S. Mole weight: 1619.91. | |
| (S)-PFI 2 hydrochloride | (S)-PFI 2 hydrochloride, a negative control of (R)-PFI 2 hydrochloride which a potent, cell-permeable inhibitor of SET7/9 (IC50 = 2 nM), shows 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer. Synonyms: (S)-PFI 2 hydrochloride; (S)-PFI2 hydrochloride; (S)-PFI-2 hydrochloride; (1S)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl]1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride. Grades: ≥97% by HPLC. CAS No. 1627607-88-8. Molecular formula: C23H25F4N3O3S.HCl. Mole weight: 535.98. | |
| Sphinganine-1-phosphate (d18:0) | Sphinganine-1-phosphate is an antagonist of the sphingosine-1-phosphate (S1P1/EDG-1) receptor with Ki value of 15 nM. It is a lipid mediator particularly for HDL. Synonyms: D-erythro-sphinganine-1-phosphate; C18-dihydro Sphingosine-1-phosphate; Dihydro-D-erythro-Sphingosine-1-phosphate; D-erythro-Dihydro-D-sphingosine-1-phosphate; [R-(R*,S*)]-2-Amino-1,3-octadecanediol 1-(Dihydrogen Phosphate); (2S,3R)-Sphinganine 1-Phosphate; C18-Dihydrosphingosine 1-Phosphate; Dihydrosphingosine-1-phosphate; (2S,3R)-2-Amino-1,3-octadecanediol 1-(Dihydrogen Phosphate). Grades: ≥95%. CAS No. 19794-97-9. Molecular formula: C18H40NO5P. Mole weight: 381.49. | |
| Sphingosine 1-phosphate | Sphingosine-1-phosphate is an endogenous second messenger that inhibits cell proliferation and motility, and Ca2+ mobilization to prevent tumor cell metastasis. Sphingosine-1-phosphate acts as an agonist at sphingosine-1-phosphate receptors (S1P1-5) and as an activator of GPR3, GPR6 and GPR12. Synonyms: D-erythro-Sphingosine-1-phosphate; C18-Sphingosine 1-phosphate; Sphing-4-enine 1-phosphate; (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate. Grades: ≥98% by HPLC. CAS No. 26993-30-6. Molecular formula: C18H38NO5P. Mole weight: 379.48. | |
| Sphingosine-1-phosphate (d16:1) | Sphingosine-1-phosphate (d16:1) is an unsaturated derivative of sphingosine-1-phosphate (S1P) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors. Synonyms: C16 S1P; C16 Sphingosine-1-phosphate; S1P (d16:1); Hexadecasphing-4-enine-1-phosphate; [(E,2S,3R)-2-amino-3-hydroxyhexadec-4-enyl] dihydrogen phosphate. Grades: ≥95%. CAS No. 709026-60-8. Molecular formula: C16H34NO5P. Mole weight: 351.4. | |
| Spirosendan | Spirosendan, a new skeletal limonoid prossessing a spiro-structure, was isolated from the root bark of Melia toosendan (Meliaceae). Synonyms: 2-Butenoic acid, 2-methyl-, (1R, 1'S, 2S, 3'R, 3'aR, 4S, 5S, 5'aR, 6'S, 6'aS, 9'S, 10'aR, 10'bR, 10'cR)-1', 3'-bis(acetyloxy)-4-(3-furanyl)decahydro-5, 6'-dihydroxy-3'a, 5, 10'b-trimethylspiro[cyclopentane-1, 7'-[7H-6a, 9]methano[1H, 4H]furo[2', 3', 4':4, 5]naphtho[2, 1-c]pyran]-2-yl ester, (2E)-; 220137-96-2. Grades: >98%. CAS No. 220137-96-2. Molecular formula: C35H46O11. Mole weight: 642.7. | |
| Spisulosine | Spisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynoma with evidence of preclinical antitumor activity. Phase I clinical trial results: Dose level VIII (200 mg/m(2)) was considered the MTD, and dose level IX (160 mg/m(2)) was defined as the RD. Limited antitumor activity was observed. Synonyms: 1-deoxysphinganine (m18:0); ES-285; ES 285; ES285; 1-deoxy SA; (2S,3R)-2-amino-3-hydroxy-octadecane; (+)-Spisulosine; 3-Octadecanol, 2-amino-, (R-(R*,S*))-; (2S,3R)-2-amino-3-octadecanol; 2S-amino-3R-octadecanol. Grades: >99%. CAS No. 196497-48-0. Molecular formula: C18H39NO. Mole weight: 285.51. | |
| SPL 334 | SPL 334 is an S-nitrosoglutathione reductase inhibitor that prevents weight loss, and alleviates lung inflammation and fibrosis in a bleomycin injury model of interstitial lung disease in mice. Synonyms: SPL-334; SPL334; SPL 334; 4-[[2-[[(2-Cyanophenyl)methyl]thio]-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl]methyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 688347-51-5. Molecular formula: C22H15N3O3S2. Mole weight: 433.5. | |
| SPL-B | SPL-B is an orally active inhibitor of transforming acidic coiled-coil protein (TACC3) exhibiting an inhibitory effect against the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells. SPL significantly inhibits mitosis in cancer cells and tumor growth. Uses: Antitumor agent. Synonyms: 8-[[ethyl(pyridin-4-ylmethyl)amino]methyl]-7-hydroxy-4-(2-oxochromen-3-yl)chromen-2-one. Grades: 98%. CAS No. 1465248-60-5. Molecular formula: C27H22N2O5. Mole weight: 454.47. | |
| SPP 86 | SPP 86 is a potent and cell-permeable RET inhibitor (IC50 = 8 nM). It also inhibits EphA1, FGFR1, Flt4, Lck and Yes. SPP 86 suppresses the proliferation of HCT 116 and TPC1 cells in vitro. Synonyms: SPP-86; SPP 86; SPP86; 1-(1-Methylethyl)-3-(2-phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-(2-phenylethynyl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine. Grades: ≥98% by HPLC. CAS No. 1357349-91-7. Molecular formula: C16H15N5. Mole weight: 277.32. | |
| SPRi 3 | SPRi 3 is a potent inhibitor of sepiapterin reductase (SPR) with IC50 value of 53-74 nM for human SPR. It inhibits BH4 synthesis pathway and attenuates proliferation in naive CD4+ T cells. Synonyms: N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide. Grades: ≥98% by HPLC. CAS No. 1292285-54-1. Molecular formula: C14H18N2O3. Mole weight: 262.3. | |
| S-Propargyl-Cysteine | S-Propargyl-cysteine (SPRC) is a modulator of endogenous hydrogen disulfide (H2S) with antioxidant activity. SPRC is potentially used for the treatment of Alzheimer's disease (TNF signaling, the NF-κB pathway and the ERK1/2 pathway), anemia of inflammation (IL-6/JAK2/STAT3 pathway), ischemic heart disease (H2S/VEGFR2/STAT3 pathway) and myocardial infarction. Synonyms: (2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid; SPRC. Grades: 98%. CAS No. 3262-64-4. Molecular formula: C6H9NO2S. Mole weight: 159.21. | |
| SPT Imidazopyridine 1 | SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM) used for the treatment of type 2 diabetes and dyslipidemia. SPT Imidazopyridine 1 inhibits incorporation of 14C-serine into ceramide in dose manner, and lowers plasma ceramide levels in vivo. It also has the effect of increasing plasma HDL and reducing VLDL cholesterol levels in rats. Synonyms: SPT-IN-1; SPT IN 1; SPT Inhibitor 1; Imidazopyridine 1; 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid; 2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid; SPT-IN-1. Grades: ≥98%. CAS No. 1933533-18-6. Molecular formula: C22H24N2O3. Mole weight: 364.44. | |
| SQ28603 | SQ28603 is a selective neutral endopeptidase (NEP 3.4.24.11) inhibitor. Synonyms: 3-[(2-benzyl-3-sulfanylpropanoyl)amino]propanoic acid; SQ 28,603; SQ 28603; SQ-28603. CAS No. 100845-83-8. Molecular formula: C13H17NO3S. Mole weight: 267.34. | |
| SQ 29548 | SQ 29548 is a potent and selective TP receptor antagonist. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 μM. Synonyms: SQ-29548; SQ29548; (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grades: ≥98%. CAS No. 98672-91-4. Molecular formula: C21H29N3O4. Mole weight: 387.5. | |
| Squarunkin A hydrochloride | Squarunkin A is an inhibitor of UNC119 chaperone protein-cargo interaction. It inhibits the binding of a myristoylated peptide representing the N-terminus of Src kinase to UNC119A with an IC50 value of 10?nm. It binds to UNC119 proteins in cell lysate and interferes with the activation of Src kinase. Synonyms: Ethyl 4-((3,4-dioxo-2-((2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)amino)cyclobut-1-en-1-yl)amino)piperidine-1-carboxylate hydrochloride. Grades: ≥98% by HPLC. CAS No. 2253744-55-5. Molecular formula: C25H32F3N5O4·HCl. Mole weight: 560.01. | |
| SR 10067 | SR 10067 is a selective and cell-permeable Rev-Erbα/β agonist (IC50 = 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively). SR 10067 has no significant activity against a wide range of nuclear receptors, other receptors, ion channels and transporters at 20 μM. SR 10067 has effects of increasing wakefulness, reducing REM and slow wave sleep in vivo. Synonyms: SR 10067; SR-10067; SR-10067; [3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone. Grades: ≥98% by HPLC. CAS No. 1380548-02-6. Molecular formula: C31H31NO3. Mole weight: 465.58. | |
| SR 11302 | SR 11302 is an inhibitor of activator protein-1 (AP-1), which is a transcription factor activity that displays antitumor effects in vivo. SR 11302 does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC50 > 1 μM for RARα, RARβ, RARγ and RXRα). Synonyms: SR 11302; SR11302; SR-11302; (E,E,Z,E)-3-Methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Grades: ≥98% by HPLC. CAS No. 160162-42-5. Molecular formula: C26H32O2. Mole weight: 376.54. | |
| SR-3029 | SR-3029, a small molecule inhibitor that targets specificly CK1δ/CK1ε, was effective at reducing the growth of breast cancer in multiple mouse models without any signs of major toxicity. IC50=97 nM. Synonyms: N-[(4,5-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-morpholin-4-ylpurin-6-amine;SR-3029; SR 3029; SR3029;SCHEMBL15243359; SCHEMBL17132207; CS-5672; CS 5672; CS5672; HY-100011; 1454585-06-8. CAS No. 1454585-06-8. Molecular formula: C23H19F3N8O. Mole weight: 480.45. | |
| SR 7826 | SR 7826 is a potent and selective LIMK inhibitor (IC50 = 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). SR 7826 was shown to inhibit cofilin phosphorylation in A7r5 cells and suppress migration and invasion of PC-3 cells in vitro. Synonyms: SR7826; SR-7826; SR 7826; N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea; 1-(2-hydroxyethyl)-3-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]-1-phenylurea. Grades: ≥98% by HPLC. CAS No. 1219728-20-7. Molecular formula: C22H21N5O2. Mole weight: 387.43. | |
| SR 8278 | SR 8278 is a nuclear heme receptor Rev-Erbα antagonist. This compound inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM) and blocks activity of Rev-Erbα agonist GSK 4112 in HEK293 cells. SR 8278 increases expression of glucose-regulating genes, G6Pase and PEPCK in HepG2 cells. Synonyms: SR8278; SR 8278; SR-8278. 1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid ethyl ester; ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate. Grades: ≥99% by HPLC. CAS No. 1254944-66-5. Molecular formula: C18H19NO3S2. Mole weight: 361.48. | |
| SRI-011381 | SRI-011381 is an activator of TGF-β signaling. Synonyms: N'-Cyclohexyl-N-(Phenylmethyl)-N-(4-Piperidinylmethyl)-Urea; SRI011381; SCHEMBL16099597; BCP30372; EX-A3008. Grades: 98%. CAS No. 1629138-41-5. Molecular formula: C20H31N3O. Mole weight: 329.5. | |
| S- (+)-Rolipram | S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer. Synonyms: (S)-(+)-rolipram; 85416-73-5; S-(+)-Rolipram(S)-ROLIPRAMS- (+)-Rolipram. Grades: >98%. CAS No. 85416-73-5. Molecular formula: C16H21NO3. Mole weight: 275.34. | |
| SRS11-92 | SRS11-92 is an effective iron death inhibitor. It inhibits Erastin-induced iron death cells in HT-1080 human fibrosarcoma cells (EC50=6 nM). Synonyms: 4-(Cyclohexylamino)-3-[(Phenylmethyl)Amino]-Benzoic acid, Ethylester. Grades: 98%. CAS No. 1467047-25-1. Molecular formula: C22H28N2O2. Mole weight: 352.5. | |
| (S,R,S)-AHPC | (S,R,S)-AHPC (MDK7526) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC (MDK7526) can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells. Synonyms: MDK7526; VH032-NH2; VHL ligand 1. CAS No. 1448297-52-6. Molecular formula: C22H30N4O3S. Mole weight: 430.56. | |
| (S,R,S)-AHPC-Me | E3 ligase Ligand 1A is a VH032 derivate for conjugation reactions of PROTAC, which can hijack VHL as the E3 ubiquitin ligase component. Synonyms: (S,R,S)-AHPC-Me; VHL ligand 2; E3 ligase Ligand 1A; 1-(2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-[1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide. CAS No. 1948273-02-6. Molecular formula: C23H32N4O3S. Mole weight: 444.59. | |
| SS5020 | SS5020 is a novel benzopyran antiestrogen and it exhibits no genotoxic activity to damage DNA. In addiction, SS5020 does not present significant uterotrophic potential in rats. SS5020 had stronger antitumor potential than those same antiestrogens against 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats when using the human equivalent molar dose of TAM. Uses: Antitumor activity. Synonyms: SS5020; SS5020; SS 5020. (E)-3-(4-((7-hydroxy-2-oxo-3-phenyl-2H-chromen-4-yl)methyl)phenyl)acrylic acid. Grades: 98%. CAS No. 1334310-70-1. Molecular formula: C25H18O5. Mole weight: 398.41. | |
| (S)-Sitagliptin N-Boc-Acid Impurity | (S)-Sitagliptin N-Boc-Acid Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 41; Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid; (βS)?-β-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-2,?4,?5-trifluoro-benzenebutanoic Acid; (S)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. Grades: >95%. CAS No. 922178-94-7. Molecular formula: C15H18F3NO4. Mole weight: 333.3. | |
| SSM 3 trifluoroacetate | SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM) which blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro. Synonyms: SSM 3 trifluoroacetate; SSM3 trifluoroacetate; SSM-3 trifluoroacetate; SSM3 TFA; SSM-3 TFA; SSM 3 TFA; SSM3 TFA salt; rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt. Grades: ≥98% by HPLC. CAS No. 922732-52-3. Molecular formula: C22H32N12O2.4CF3CO2H. Mole weight: 952.66. | |
| SSR 69071 | SSR 69071 is a potent and high affinity human leukocyte elastase (HLE) inhibitor (IC50 = 3.9 nM) that displays species-selectivity (Ki = 0.017, 1.70, 3.01, 58 and > 100 nM for human, mouse, rat, rabbit and porcine elastase, respectively). SSR 69071 has been shown to inhibit HLE-induced lung hemorrhage in mice (ID50 = 2.8 mg/kg) and reduce infarct size in an in vivo acute model of coronary ischemia-reperfusion injury. Synonyms: SSR 69071; SSR69071; SSR-69071; 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: ≥98% by HPLC. CAS No. 344930-95-6. Molecular formula: C27H32N4O7S. Mole weight: 556.63. | |
| ST-193 | ST-193 is a potent, broad-spectrum small-molecule inhibitor of arenavirus entry and exhibits submicromolar antiviral activity in vitro. ST-193 inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively. Synonyms: 1-(4-methoxyphenyl)-N-[(4-propan-2-ylphenyl)methyl]benzimidazol-5-amine; ST-193; ST 193; ST193. Grades: 99.86%. CAS No. 489416-12-8. Molecular formula: C24H25N3O. Mole weight: 371.47. | |
| ST-193 hydrochloride | ST-193 hydrochloride is the hydrochloride salt of ST-193 which is a potent, broad-spectrum small-molecule inhibitor of arenavirus entry and exhibits submicromolar antiviral activity in vitro. Synonyms: 1-(4-methoxyphenyl)-N-[(4-propan-2-ylphenyl)methyl]benzimidazol-5-amine;hydrochloride; ST-193 hydrochloride; ST 193 hydrochloride; ST193 hydrochloride. Molecular formula: C24H26ClN3O. Mole weight: 407.94. | |
| ST271 | A potent inhibitor of protein tyrosine kinase (PTK). Synonyms: (E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide; 2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-; ST 271; ST-271; ST271. CAS No. 106392-48-7. Molecular formula: C16H20N2O2. Mole weight: 272.34. | |
| ST 2825 | ST 2825 is a MyD88 pharmacologic inhibitor. It inhibited MyD88 dimerization in coimmunoprecipitation experiments. It interfered with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1beta-mediated activation of NF-kappaB transcriptional activity. Synonyms: ST-2825; ST 2825; ST2825. Grades: >98%. CAS No. 894787-30-5. Molecular formula: C27H28Cl2N4O5S. Mole weight: 591.51. | |
| ST638 | ST638 is a tyrosine kinase inhibitor and PLD inhibitor. It suppresses tyrosine phosphorylation induced by tumor necrosis factor-α and phorbol myristate acetate in neutrophils and by angiotensin II in cardiac fibroblasts. Uses: Enzyme inhibitors. Synonyms: (Z)-2-cyano-3-[3-ethoxy-4-hydroxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide. Grades: ≥98%. CAS No. 107761-24-0. Molecular formula: C19H18N2O3S. Mole weight: 354.4. | |
| Stachyose hydrate | Stachyose hydrate is a natural oligosaccharide commonly found in plant sources acting as a prebiotic aiding in the research of beneficial gut bacteria. Synonyms: Lupeose. CAS No. 54261-98-2. Molecular formula: C24H42O21·xH2O. Mole weight: 666.58 (anhydrous basis). | |
| STAD 2 | STAD 2 is a cell-permeable AKAP disruptor that binds to PKA-RII and blocks the interaction of it with AKAP. CAS No. 1542100-77-5. Molecular formula: C102H182N24O22. Mole weight: 2096.68. | |
| Starch Dialdehyde | Starch Dialdehyde, a crucial compound in the biomedical industry, serves as a crosslinking agent for proteins and polysaccharides. Its notable anticoagulation properties come to bear in the production of dialysis and heparin systems. Moreover, Starch Dialdehyde boasts tremendous potential as a drug carrier for targeted drug delivery in cancer therapy. Grades: >98%. CAS No. 9085-99-8. | |
| STAT5-IN-1 | STAT5-IN-1, a cell-permeable nonpeptidic nicotinoyl hydrazone compound, is a selective STAT5 inhibitor with an IC50 of 47 μM for STAT5β isoform with much less effect towards the SH2 domain of STAT1, STAT3, or Lck (IC50>500 μM). Synonyms: MDK-6314; STAT5 Inhibitor; STAT5Inhibitor; STAT5-Inhibitor; MDK 6314; MDK6314. N-[(E)-(4-oxochromen-3-yl)methylideneamino]pyridine-3-carboxamide; STAT5 Inhibitor. CAS No. 285986-31-4. Molecular formula: C16H11N3O3. Mole weight: 293.28. | |
| StemRegenin 1 | StemRegenin 1 is an aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM. It has been reported to promote hematopoietic stem cell expansion. Synonyms: 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol; SR1. Grades: >98%. CAS No. 1227633-49-9. Molecular formula: C24H23N5OS. Mole weight: 429.542. | |
| STF-083010 | STF-083010 is a novel small-molecule inhibitor of Ire1α; inhibits Ire1 endonuclease activity, without affecting its kinase activity after endoplasmic reticulum stress both in vitro and in vivo. Synonyms: STF-083010; STF 083010; STF083010, IRE1 Inhibitor I. Grades: >98%. CAS No. 307543-71-1. Molecular formula: C15H11NO3S2. Mole weight: 317.38. | |
| Stiripentol | Stiripentol is an anticonvulsant drug used in the treatment of epilepsy. Synonyms: Diacomit; BCX 2600; (E)-1-(1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol. Grades: >95%. CAS No. 49763-96-4. Molecular formula: C14H18O3. Mole weight: 234.29. | |
| STK321130 | STK321130 is potent FLT3 inhibitor with IC50 value of less than 1 μM. Synonyms: STK321130; STK 321130; STK-321130; FLT3-IN-2;5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine;2-Pyridinamine, 5-[ (5-chloro-1H-pyrrolo[2, 3-b]pyridin-3-yl) methyl]-N-[[4- (trifluoromethyl) phenyl]methyl]-) ; 5-[ (5-Chloro-1H-pyrrolo[2, 3-b]pyridin-3-yl) methyl]-N-[[4- (trifluoromethyl) phenyl]methyl]pyridin-2-amine. Grades: >98%. CAS No. 923562-23-6. Molecular formula: C21H16ClF3N4. Mole weight: 416.83. | |
| STO-609 acetate | STO-609 acetate is a selective and cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (CaMKK) (Ki = 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ, respectively). It displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. STO-609 can be used as a tool for evaluating the physiological significance of the CaM-KK-mediated pathway in vivo and in vitro. Synonyms: STO-609 acetate; STO 609 acetate; STO609 acetate; 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate. Grades: ≥98% by HPLC. CAS No. 1173022-21-3. Molecular formula: C19H10N2O3.C2H4O2. Mole weight: 374.35. | |
| STOCK2S 26016 | STOCK2S 26016 is a cell-permeable lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 μM). STOCK2S 26016 inhibits the binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively. Synonyms: 7-Ethoxy-N3-(2-furanylmethyl)-3,9-acridinediamine; WNK-IN-B; WNK IN B; Compound B; BAS 01862286; GNF-Pf-3043. Grades: ≥98% by HPLC. CAS No. 332922-63-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| Streptavidin | Streptavidin is a tetrameric bacterial protein isolated from Streptomyces avidinii. Streptavidin shows high affinity for biotin. Synonyms: Streptavidin, Avidin, Streptomyces avidinii. CAS No. 9013-20-1. | |
| Stylopine hydrochloride | Stylopine hydrochloride is a natural compound isolated from the leaves of Chelidonium majus L. Synonyms: Tetrahydrocoptisine hydrochloride. Grades: 98.5%. CAS No. 96087-21-7. Molecular formula: C19H18ClNO4. Mole weight: 359.806. | |
| SU5402 | SU5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor. Synonyms: SU-5402; SU 5402. Grades: 0.98. CAS No. 215543-92-3. Molecular formula: C17H16N2O3. Mole weight: 296.32054. | |
| Succinyl phosphonate | Succinyl phosphonate was found to be effective inhibitors of alpha-ketoglutarate oxidative decarboxylation, catalyzed by both muscle and bacterial alpha-ketoglutarate dehydrogenase complexes, as well as muscle alpha-ketoglutarate dehydrogenase. Synonyms: Succinyl phosphonate. Grades: >98%. CAS No. 26647-82-5. Molecular formula: C4H7O6P. Mole weight: 182.07. | |
| Sucrose octasulfate sodium salt | Sucrose octasulfate sodium salt is a fascinating and bio-medicinal compound, aiding in studying the bothersome afflictions of chronic venous ulcers and inflammation. Synonyms: α-D-Glucopyranoside, 1,3,4,6-tetra-O-sulfo-β-D-fructofuranosyl, 2,3,4,6-tetrakis(hydrogen sulfate), sodium salt (1:x); α-D-Glucopyranoside, 1,3,4,6-tetra-O-sulfo-β-D-fructofuranosyl, tetrakis(hydrogen sulfate), sodium salt; Sucrosofate sodium salt; 1,3,4,6-Tetra-O-sulfo-β-D-fructofuranosyl α-D-Glucopyranoside 2,3,4,6-Tetrakis(hydrogen sulfate) Sodium Salt; Sodium Sucrose Octasulfate. Grades: 95%. CAS No. 127930-09-0. Molecular formula: C12H22O35S8.xNa. Mole weight: 982.80 (free acid). | |
| Sucunamostat | Sucunamostat is an enteropeptidase inhibitor. Synonyms: sucunamostatum; L-Aspartic acid, N-[2-[ (3S)-6-[[4-[ (aminoiminomethyl)amino]benzoyl]oxy]-2, 3-dihydro-3-benzofuranyl]acetyl]-; N-[[(3S)-6-[(4-Guanidinobenzoyl)oxy]-2,3-dihydrobenzofuran-3-yl]acetyl]-L-aspartic acid. Grades: >98%. CAS No. 1802888-04-5. Molecular formula: C22H22N4O8. Mole weight: 470.4. | |
| Sulfabenzamide | Sulfabenzamide is a widely used intermediate in many chemical areas and has been found to have antibacterial activity. Uses: Sulfabenzamide is a widely used intermediate in many chemical areas and has been found to have antibacterial activity. Synonyms: sulfabenzamide; Sulfabenzid; Sulfabenzide; 127-71-9; Sulfabenzoylamide; N-Sulfamylbenzamide. Grades: 95%. CAS No. 127-71-9. Molecular formula: C13H12N2O3S. Mole weight: 276.31. | |
| Sulfacarbamide | Sulfacarbamide is an antibiotic acting on the vegetative nervous system. Uses: Antibiotic. Synonyms: (4-aminophenyl)sulfonylurea; 1- (4-Aminobenzenesulfonyl) urea; 1-Amino-4- ([ (aminocarbonyl) amino]sulfonyl) benzene. Grades: ≥98%. CAS No. 547-44-4. Molecular formula: C7H9N3O3S. Mole weight: 215.22. | |
| Sulfacetamide | Sulfacetamide is a sulfonamide antibiotic as a dihydropteroate Synthase inhibitor. It is a competitive inhibitor of bacterial para-aminobenzoic acid, which is required for bacterial synthesis of folic acid. Sulfacetamide is used for the treatment of skin infections and urinary tract infections. It is also used to treat acne and seborrheic dermatitis. Uses: Skin infections and urinary tract infections;treat acne and seborrheic dermatitis. Synonyms: NSC63871; NSC-63871; NSC 63871; Sulfacetamide; Region; Sebizon; N-[(4-aminophenyl)sulfonyl]acetamide; 4-(Acetylaminosulfonyl)aniline; A 500; Acetocid; Acetosulfamin; Acetosulfamine; Albamine; Albucid; Alesten; Formosulfacetamide; N-(4-Aminobenzenesulfonyl)acetamide; N-(p-Aminophenylsulfonyl)acetamide; N-Acetylsulfanilamide; N-Sulfanilylacetamide; N-[(4-Aminophenyl)sulfonyl]acetamide; N1-Acetylsulfanilamide; NSC 63871; N'-Acetylsulfanilamide; Ocusol; Region; Steramide; Sulamyd; Sulfacet; Sulfacetamide; Sulfacetimide; Sulfacyl; Sulphacetamide; Sulphasil; Urosulfon; p-Aminobenzenesulfonacetamide; N-[(4-aminophenyl)sulfonyl]acetamide; N-Sulfanilyacetamide. Grades: 98%. CAS No. 144-80-9. Molecular formula: C8H10N2O3S. Mole weight: 214.24. | |
| Sulfamethoxypyridazine | Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic. It is used for treatment of Dermatitis herpetiformis. Uses: Sulfamethoxypyridazine is used for treatment of dermatitis herpetiformis. Synonyms: Sulfanilamide, N1-(6-methoxy-3-pyridazinyl)-; Sulfdurazin; Sulfozona; Sultirene; Surirene; Sulfalex; 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide; 3-Sulfanilamido-6-methoxypyridazine; 6-Methoxy-3-pyridazinylsulfanilamide; 6-Sulfanilamido-3-methoxypyridazine; Altezol; Davosin; Davozil; Depovernil; Kinex; Kynex; Lederkin; Lederkyn; Longin; Midicel; Myasul; Paramid; Piridolo. Grades: >98.0%(LC). CAS No. 80-35-3. Molecular formula: C11H12N4O3S. Mole weight: 280.30. | |
| Sulf-DBCO-NHS ester | Sulf-DBCO-NHS ester, a cutting-edge chemical reagent, finds its application in the field of biomedicine, serving as a versatile biomolecule labeling and tracking agent. Featuring a DBCO functional group, it selectively binds to the azide residues on proteins or nucleic acids. The ease of incorporation of the product into various assays and diagnostic tools makes it an ideal candidate for designing probes or conjugates. Its efficacy and efficiency have garnered great interest, and it is widely being adopted for various biomedical explorations. CAS No. 1379761-19-9. Molecular formula: C23H17N2NaO8S. Mole weight: 504.4. | |
| Sulfo-SMCC sodium | Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. Synonyms: Sulfo-SMCC; Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate. Grades: >98.0%. CAS No. 92921-24-9. Molecular formula: C16H17N2NaO9S. Mole weight: 436.37. | |
| Sulfosuccinimidyl oleate sodium salt | Sulfosuccinimidyl oleate (SSO) is an irreversible inhibitor of the fatty acid translocase CD36. It binds to CD36 and suppresses the fatty acid uptake and signaling to calcium. Synonyms: SSO; 1-[(Z)-octadec-9-enoyl]oxy-2,5-dioxopyrrolidine-3-sulfonic acid sodium salt. Grades: ≥95%. Molecular formula: C22H36NO7S·Na. Mole weight: 482.6. | |
| Sulglicotide | Sulglicotide can be used for the treatment of peptic ulcer and gastro-oesophageal reflux disease. Synonyms: sulglycotide. Grades: >95%. CAS No. 54182-59-1. | |
| Sulprostone | Sulprostone is a synthetic PGE2 analog that acts as a selective EP3 and EP1 receptor agonist (Ki = 0.6 and 21 nM, respectively). Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity. Uses: Abortifacient agents, nonsteroidal. Synonyms: (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide. CAS No. 60325-46-4. Molecular formula: C23H31NO7S. Mole weight: 465.56. | |
| Sultamicillin tosylate | Sultamicillin is a compound composed of sulbactam and ampicillin linked as a double ester. Sulbactam is a semisynthetic beta-lactamase inhibitor, which exhibits improved antibacterial activity in combination with ampicillin. Synonyms: Bacimex; Unacim orale. CAS No. 83105-70-8. Molecular formula: C32H38N4O12S3. Mole weight: 766.86. | |
| Sumatriptan | Sumatriptan is a Serotonin-1b and Serotonin-1d Receptor Agonist that acts selectively at 5HT1 receptors. It is a sulfonamide triptan with vasoconstrictor activity. It selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system, thus constricts cerebral blood vessels. It may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater. It is a medication used for the treatment of migraine headaches. Uses: Sumatriptan is a medication used for the treatment of migraine headaches. Synonyms: Imitrex; Sumatran; Sumax; Sumatriptanum; 1-[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide; (3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide; GR-43175; GR43175. Grades: 95%. CAS No. 103628-46-2. Molecular formula: C14H21N3O2S. Mole weight: 295.40. | |
| Sunifiram | unifiram (DM-235) is a piperazine derived research chemical which has nootropic effects in animal studies with significantly higher potency than piracetam. Synonyms: DM-235; DM 235; DM235. Grades: >98%. CAS No. 314728-85-3. Molecular formula: C14H18N2O2. Mole weight: 246.3. | |
| Sunvozertinib | Sunvozertinib is a tyrosine kinase inhibitor with anti-tumor effects. Grades: >98%. CAS No. 2370013-12-8. Molecular formula: C29H35ClFN7O3. Mole weight: 584.1. | |
| Super-TDU | Super-TDU is an inhibitory peptide targeting YAP-TEADs interaction. Synonyms: Super-TDU; 1599441-71-0; s8554. CAS No. 1599441-71-0. Molecular formula: C237H370N66O69S. Mole weight: 5279.94. | |
| Suplatast Tosylate | Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM. Synonyms: IPD-1151T. Grades: >98%. CAS No. 94055-76-2. Molecular formula: C23H33NO7S2. Mole weight: 499.64. | |
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