BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tectorigenin 7-O-xylosylglucoside | Tectorigenin 7-O-xylosylglucoside is a compound of the flavonoid class. Synonyms: 6''-O-Xylosyltectoridin; 5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one. Grades: >98%. CAS No. 231288-19-0. Molecular formula: C27H30O15. Mole weight: 594.522. |  |
| Telavancin hydrochloride | Telavancin hydrochloride, a derivative of vancomycin, is a potent medication used to combat an array of bacterial infections. These infections include, but are not limited to, skin and soft tissue infections, bloodstream infections caused by Staphylococcus aureus, and Streptococcus pyogenes. Its mode of action is to repress the synthesis of bacterial cell walls. Its efficacy against methicillin-resistant organisms makes it a highly effective option against bacterial infections in clinical settings. Synonyms: Telavancin Hydrochloride; 560130-42-9; Telavancin HCl; Vibativ; UNII-0701472ZG0. CAS No. 560130-42-9. Molecular formula: C80H106Cl2N11O27P·HCl. Mole weight: 1792.096. | |
| Telmapitant | Telmapitant is a neurokinin NK1 receptor antagonist. Synonyms: (5R, 8S) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 3, 9-triazaspiro[4. 5]decane-2, 4-dione. Grades: 98%. CAS No. 552292-58-7. Molecular formula: C24H23F6N3O3. Mole weight: 515.45. | |
| Telmisartan Impurity J | Telmisartan Impurity J is one of telmisartan impurities. Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension. Synonyms: Telmisartan Chloro Impurity; Telmisartan impurity J [EP]; 4'-[(5-chloro-1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-carboxylic acid. Grades: > 98%. CAS No. 885045-90-9. Molecular formula: C33H29ClN4O2. Mole weight: 549.06. | |
| Telmisartan Related Compound B | One of the impurities of Telmisartan, which is an angiotensin II receptor antagonist and could be used in the treatment of hypertensive. Synonyms: 4'-[(1,7'-Dimethyl-2'-propyl[2,5'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic Acid. Grades: > 95%. CAS No. 1026353-20-7. Molecular formula: C33H30N4O2. Mole weight: 514.6. | |
| Telocinobufagin | Telocinobufagin is one of anti-hepatoma constituent in Venenum Bufonis. Synonyms: Telobufotoxin; Telocinobufogenin. Grades: >98%. CAS No. 472-26-4. Molecular formula: C24H34O5. Mole weight: 402.52. | |
| Telomerase-IN-1 | Telomerase-IN-1 is a Telomerase inhibitor (IC50= 0.19 μM). Synonyms: (4-fluorophenyl)-[1-[2-methoxy-2-(4-nitrophenyl)ethyl]piperidin-4-yl]methanone; FDXXXOGKSMENLY-UHFFFAOYSA-N. CAS No. 666859-49-0. Molecular formula: C21H23FN2O4. Mole weight: 386.42. | |
| Temozolomide Acid | Temozolomide acid is an active metabolite of temozolomide(T017775) with anticancer activity in vitro. Temozolomide is an alkylating agent used as a treatment of some brain cancer, a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.In Apr 2016, Stanford University and Merck suspended enrolment in a phase II trial for Acute myeloid leukaemia (Combination therapy, Newly diagnosed, Second-line therapy or greater) in USA. In 14 Jul 2016, Medivation planed a phase II trial for Endometrial cancer in USA (NCT02836028) After two days, M.D. Anderson Cancer Center completed a phase II trial in Malignant melanoma (Late-stage disease, Neoadjuvant therapy, Monotherapy, Combination therapy) in USA. Uses: As an antitumor agent. Synonyms: 3,4-Dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic Acid; 3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxylic Acid; Temozolomide-8-carboxylic Acid; TMZA. Grades: 98%. CAS No. 113942-30-6. Molecular formula: C6H5N5O3. Mole weight: 195.14. | |
| Tenatoprazole sodium | Tenatoprazole is a novel proton pump inhibitor which is similar to the chemical structure of omeprazole, a widely used proton pump inhibitor. Tenatoprazole belongs to the class of covalent proton pump inhibitors and inhibits gastric H+,K+-ATPase with potency similar to omeprazole. Synonyms: 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine;sodium. CAS No. 335299-59-7. Molecular formula: C16H18N4NaO3S. Mole weight: 369.39. | |
| Teneligliptin HBr | Teneligliptin hydrobromide is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor. It competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro. Synonyms: [(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone Hydrobromide (2:5); Teneligliptin Hydrobromide (2:5). Grades: >98%. CAS No. 906093-29-6. Molecular formula: C44H65Br5N12O2S2. Mole weight: 1257.72. | |
| Tenilsetam | Tenilsetam is an endonuclease modulator, also a nootropic agent and advanced glycation end product (AGE) inhibitor with the potential to treat Alzheimer's disease (AD). Preclinical studies indicated that tenilsetam may have an inhibitory effect on diabetic retinopathy, without amelioration of pericyte loss. Uses: Potential treatment of alzheimer's disease. Synonyms: 3-(thiophen-2-yl)piperazin-2-one; 3-thiophen-2-ylpiperazin-2-one; 3-(2-thienyl)piperazin-2-one. Grades: 99%. CAS No. 86696-86-8. Molecular formula: C8H10N2OS. Mole weight: 182.24. | |
| Tenovin-2 | Tenovin-2, a diminutive compound inhibitor, offers promise as a therapeutic agent for a range of malignancies, including but not limited to breast cancer and leukemia. Its mechanism of action is attributed to the activation of p53, a multifunctional protein responsible for regulating cellular growth and division. Synonyms: 4-Tert-butyl-N-[[4- (2-methylpropanoylamino) phenyl]carbamothioyl]benzamide; N-[4- ({[ (4-tert-butylbenzoyl) amino]carbothioyl}amino) phenyl]-2-methylpropanamide. CAS No. 666211-30-9. Molecular formula: C22H27N3O2S. Mole weight: 397.537. | |
| TEPP-46 | TEPP-46, an effective sensitizer of recombinant pyruvate kinase M2, has been found to decrease the formation of tumor in a mouse xenograft model. IC50: 92 nM (AC50). Uses: Tepp-46 has been found to decrease the formation of tumor in a mouse xenograft model. Synonyms: ML265; ML-265; ML 265; CID44246499; CID-44246499; CID 44246499; NCGC00186528; NCGC 00186528; NCGC-00186528; TEPP46; TEPP 46; TEPP-46; 6-[(3-aminophenyl)methyl]-4,6-dihydro-4-methyl-2-(methylsulfinyl)-5h-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one; ML265; TEPP 46; MLS006010294. Grades: 95%. CAS No. 1221186-53-3. Molecular formula: C17H16N4O2S2. Mole weight: 372.46. | |
| Terbuthylazine | Terbuthylazine is a triazine herbicide. Uses: A selective herbicide. Synonyms: 6-Chloro-N2-(1,1-dimethylethyl)-N4-ethyl-1,3,5-triazine-2,4-diamine; 6-Chloro-N-(1,1-dimethylethyl)-N'-ethyl-1,3,5-triazine-2,4-diamine. Grades: ≥95%. CAS No. 5915-41-3. Molecular formula: C9H16ClN5. Mole weight: 229.71. | |
| Terbutryn | Terbutryn is a chemical compound with a triazine ring as a basic structure. It is used as a herbicide. It also acts as an inhibitor of photosynthesis. It is absorbed by the roots and foliage. Uses: Terbutryn is used as a herbicide. it also acts as an inhibitor of photosynthesis. Synonyms: 1,3,5-Triazine-2,4-diamine, N-(1,1-dimethylethyl)-N'-ethyl-6-(methylthio)-;2-(tert-butylamino)-4-(ethylamino)-6-(methylthio)-s-triazin;2-Methylthio-4-ethylamino-6-tert-butylamino-s-triazine;2-tert.Butylamino-4-aethylamino-6-methylthio-1,3,5-triazin;methylmercapto-s-triazine;4-Aethylamino-2-tert-butylamino-6-methylthio-s-triazin;5-triazine-2,4-diamine,n-(1,1-dimethylethyl)-n'-ethyl-6-(methylthio)-3;Clarosan;Prebane;2-N-tert-butyl-4-N-ethyl-6-methylsulfanyl-1,3,5-triazine-2,4-diamine. Grades: >98 %. CAS No. 886-50-0. Molecular formula: C10H19N5S. Mole weight: 241.35. | |
| Terephthalamidine | Terephthalamidine, a phthalanilide derivative, could bind to DNA double helix selectively. Synonyms: Terephthalamidine; 1,4-Diamidinobenzene; 1,4-Benzenedicarboximidamide; Benzene-1,4-dicarboximidamide. Grades: 98%. CAS No. 15411-54-8. Molecular formula: C8H10N4. Mole weight: 162.20. | |
| Terephthalic acid hexamethylenediamine salt (1:1) | Terephthalic acid hexamethylenediamine salt (1:1), a fundamental component utilized in biomedical engineering's synthesis of polyamide resins, is extensively implemented in a myriad of medical devices, including but not limited to catheters and surgical sutures. These resins' unique anti-microbial abilities make them an ideal choice, ensuring that microbial infections are averted, thus ensuring optimum medicinal applications. Synonyms: Hexamethylene diamine terephthalate; Hexamethylendiaminterephthalat. CAS No. 3160-86-9. Molecular formula: C14H22N2O4. Mole weight: 282.34. | |
| Terephthalimidamide dihydrochloride | Terephthalimidamide dihydrochloride, a popular chemical compound in the biomedical industry, has garnered attention for its potential as a therapeutic agent for Alzheimer's disease. This is due to its remarkable antioxidant and anti-inflammatory properties which actively curb oxidative stress and inflammation - both of which are entwined with the onset and progression of the disease. With its ability to check amyloid-β peptide aggregation and prevent neuronal cell damage, Terephthalimidamide dihydrochloride is a highly promising contender for the creation of novel Alzheimer's treatments. Synonyms: 1,4-Benzenedicarboximidamide dihydrochloride. CAS No. 14401-56-0. Molecular formula: C8H12Cl2N4. Mole weight: 235.11. | |
| Teriparatide Acetate | Cas No. 99294-94-7. | |
| Terminolic acid | Terminolic acid, a pentacyclic triterpenoid glycoside isolated from Combretum racemosum, inhibits pro-inflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6, and enhances anti-inflammatory cytokines by binding to IL-4 receptor binding sites. It also shows moderate antibacterial activity. Synonyms: 2α,6β,23-trihydroxyl oleanolic acid; Olean-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-; 2,3,6,23-Tetrahydroxyolean-12-en-28-oic acid, (2alpha,3beta,4alpha,6beta)-; (2α,3β,6β)-2,3,6,23-Tetrahydroxyolean-12-en-28-oic acid. Grades: ≥95%. CAS No. 564-13-6. Molecular formula: C30H48O6. Mole weight: 504.70. | |
| Tert-butyl 4-{[4- (trifluoromethoxy) phenyl]carbamoyl}piperidine-1-carboxylate | Cas No. 308830-70-8. Molecular formula: C18H23F3N2O4. Mole weight: 388.4. | |
| tert-Butyldimethylsilanol | Tert-Butyldimethylsilanol, a reactive intermediate of paramount importance in the biomedical industry, holds a plethora of applications for synthesizing diverse drugs and siloxane polymers. Its potential in treating liver fibrosis through the inhibition of hepatic stellate cell proliferation has also been probed meticulously. The compound's multifaceted role in medicine and biotechnology accentuates its relevance in scientific research and practical applications. Synonyms: t-Butyldimethylsilanol. Grades: 95%. CAS No. 18173-64-3. Molecular formula: C6H16OSi. Mole weight: 132.28. | |
| Tesamorelin | Tesamorelin is the N-terminally modified peptide of human GHRH, which is used in the treatment of HIV-associated lipodystrophy. Grades: 98%. CAS No. 218949-48-5. Molecular formula: C221H366N72O67S. Mole weight: 5135.86. | |
| Tetrabenazine | Tetrabenazine is a VMAT inhibitor used for the treatment of hyperkinetic movement disorder. It is a monoamine-depleting and dopamine-receptor-blocking drug, and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (3R,11bR)-rel-; 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-; (±)-Tetrabenazine; cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine; NSC 169886; NSC 172187; Ro 1-9569; Rubigen; Xenazine. Grades: >98%. CAS No. 58-46-8. Molecular formula: C19H27NO3. Mole weight: 317.42. | |
| Tetrabromophenolphthalein Ethyl Ester Potassium Salt | Synonyms: Potassium tetrabromophenolphthalein ethyl ester; Potassium 2, 6-dibromo-4- ( (3, 5-dibromo-4-oxocyclohexa-2, 5-dien-1-ylidene) (2- (ethoxycarbonyl) phenyl) methyl) phenolate; TBPE. CAS No. 62637-91-6. Molecular formula: C22H13Br4KO4. Mole weight: 700.06. | |
| Tetrabutylammonium hydrogen carbonate | Tetrabutylammonium hydrogen carbonate is a useful research chemical. Synonyms: tetrabutylammonium bicarbonate; tetrabutylammonium hydrogencarbonate. Grades: 98% by 1H NMR. CAS No. 17351-62-1. Molecular formula: C17H37NO3. Mole weight: 303.5. | |
| Tetrabutylammonium periodate | Tetrabutylammonium periodate is an invaluable chemical compound with a myriad of applications in the synthesis of diverse organic and inorganic compounds. It has gained widespread recognition for its exceptional efficiency and selectivity in the conversion of alcohols to aldehydes or ketones and sulfides to sulfoxides. Researchers have explored the potential of Tetrabutylammonium periodate as a reagent for selective oxidation of carbohydrates and glycosides. Its unique properties have heightened its significance in various fields of study. Synonyms: n-tetrabutylammonium periodate; Tetra-n-butylammonium periodate. Grades: 95%. CAS No. 65201-77-6. Molecular formula: C16H36N.IO4. Mole weight: 433.37. | |
| Tetracalcium diphosphorus nonaoxide | Tetracalcium diphosphorus nonaoxide, a paramount compound in biomedical industry, serves as an efficacious treatment for various bone diseases and defects including osteoporosis. Extensive research has proven its potential to induce bone regeneration and growth with considerable therapeutic implications. Its inherent structure and properties can be accessed through several chemical databases and reputable research publications, empowering the scientific community with elucidative insights. Synonyms: Tetracalcium phosphate; tetracalcium oxygen(-2) anion diphosphate; Thomas phosphate; Calcium oxide phosphate (4:1:2). Grades: 95%. CAS No. 1306-01-0. Molecular formula: Ca4O(PO4)?2. Mole weight: 366.25. | |
| Tetracosanedioic acid | Tetracosanedioic acid, an ample dicarboxylic acid, is a ubiquitous building block in the synthesis of organic compounds and high-performance polymers. In addition, potential medical applications of this multifaceted molecule have been probed, including its potential role in mitigating metabolic illnesses like diabetes and hyperlipidemia, owing to its potent ability to regulate lipid metabolism in adipose tissue and the hepatic system. Grades: 95%. CAS No. 2450-31-9. Molecular formula: C24H46O4. Mole weight: 398.62. | |
| Tetracosanedioic acid mono-tert-butyl ester | Tetracosanedioic acid mono-tert-butyl ester, a chemical entity prevalently utilized in the biomedical domain, confers anti-inflammatory effect on account of certain properties it bears. This compound constrains the manufacturing of pro-inflammatory cytokines besides mitigating the inflammatory response, in an array of animal models. Subsequently, it showcases prospective therapeutic ability for countering prevalent disorders such as atherosclerosis and rheumatoid arthritis, thereby paving way for effective medical management. Molecular formula: C28H54O4. Mole weight: 454.73. | |
| Tetradecyl phosphonate | Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors with IC50 values of 10 μM, 5.5 μM, and 3.1 μM for inhibition of LPA-induced calcium mobilization, respectively. Synonyms: Tetradecylphosphonic acid; 1-Tetradecanephosphonic acid; n-Tetradecylphosphonic acid. Grades: ≥98%. CAS No. 4671-75-4. Molecular formula: C14H31O3P. Mole weight: 278.4. | |
| Tetraethylammonium hexafluorophosphate | Synonyms: tetraethyl-ammoniuhexafluorophosphate. Grades: ≥99%. CAS No. 429-07-2. Molecular formula: C8H20N.F6P. Mole weight: 275.21. | |
| Tetraethylene glycol monoethyl ether | Tetraethylene glycol monoethyl ether can be used as a PROTAC linker. Synonyms: Tetraethylene glycol monoethyl ether; Tetraethylene glycol, monoethyl ether; Ethyl-PEG4-alcohol. Grades: 95 %. CAS No. 5650-20-4. Molecular formula: C10H22O5. Mole weight: 222.28. | |
| Tetrahydro-2,5-dimethyl-2H-pyranmethanol | Tetrahydro-2,5-dimethyl-2H-pyranmethanol (CAS# 54004-46-5 ) is a useful research chemical. Synonyms: (2,5-Dimethyloxan-2-yl)methanol. Grades: 95 %. CAS No. 54004-46-5. Molecular formula: C8H16O2. Mole weight: 144.214. | |
| Tetrahydro-6-undecyl-2H-pyran-2-one | Tetrahydro-6-undecyl-2H-pyran-2-one (CAS# 7370-44-7 ) is a useful research chemical. Synonyms: 5-Hexadecanolide; delta-hexadecalactone. CAS No. 7370-44-7. Molecular formula: C16H30O2. Mole weight: 254.41. | |
| Tetrahydrobiopterin | Tetrahydrobiopterin, a pteridin derivative, has been found to be a cofactor to form nitric oxide and neurotransmitters serotonin. Synonyms: 5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinon;5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinone;bh4;TETRAHYDRO-L-BIOPTERIN, DIHYDROCHLORIDE;THB, 2HCL;6R-BH4;(6R)-BH4 2HCL;[6R-[6R*(1R*,2S*)]]-2-AMINO-6-(1,2-DIHYDRO. Grades: 98%. CAS No. 17528-72-2. Molecular formula: C9H15N5O3. Mole weight: 241.25. | |
| Tetrahydrolavandulol | Tetrahydrolavandulol, a vital constituent in the realm of pharmacology, has been studied comprehensively due to its significant potential in treating anxiety and depression. Its functionality relies on positively modulating GABAA receptors, an allosteric mechanism that boosts the activity of GABA in the brain, thereby enabling a calming effect to prevail. Synonyms: 2-Isopropyl-5-methylhexan-1-ol. Grades: >98.0%(GC). CAS No. 2051-33-4. Molecular formula: C10H22O. Mole weight: 158.28. | |
| Tetrahydropalmatine | Tetrahydropalmatine is isolated from the tubers of Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu. It depletes neurotransmitters, such as dopamine, noradrenaline and serotonin. Uses: Antibacterial. Synonyms: (13aS)-2,3,9,10-Tetramethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine;(S)-Tetrahydropalmitine. Grades: 0.975. CAS No. 2934-97-6. Molecular formula: C21H25NO4. Mole weight: 355.42. | |
| Tetrahydropiperine | Tetrahydropiperine is a piperine alkaloid originally isolated from P. longum. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH) and 7-methoxycoumarin O-demethylase (MOCD) activity in rat liver microsomes. Synonyms: THP; Tetrahydropiperin; 5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpentan-1-one. Grades: ≥95%. CAS No. 23434-88-0. Molecular formula: C17H23NO3. Mole weight: 289.4. | |
| Tetrakis(2-propynyloxymethyl)methane | Tetrakis(2-propynyloxymethyl)methane can be used in the synthesis of Aminoglycoside Cyclic Oligosaccharides. Synonyms: Tetra(propargyloxymethyl)methane; Tetrakis(2-propynyloxymethyl) methane. Grades: 95 %. CAS No. 127751-08-0. Molecular formula: C17H20O4. Mole weight: 288.34. | |
| Tetrapeptide-30 | Tetrapeptide-30 is an indegredient in cosmetics with anti-aging effects. Synonyms: L-Prolyl-L-lysyl-L-glutamyl-L-lysine. Grades: 98%. CAS No. 1036207-61-0. Molecular formula: C22H40N6O7. Mole weight: 500.6. | |
| Tetrasodium carbonylbis(phosphonate) | Tetrasodium Carbonylbis(phosphonate), a versatile chelating agent that effectively combats scale production and corrosion. Its pharmacological applications are equally significant, serving as an ideal complexing agent for medicinal drugs. Notably, it boasts of exemplary stability and low toxicity, making it a preferred option across multiple industries. Synonyms: Tetrasodium carbonyldiphosphonate; Carbonylbis(phosphonic acid disodium) salt. Grades: 95%. CAS No. 14255-62-0. Molecular formula: CNa4O7P2. Mole weight: 277.91. | |
| Tetrasodium N-(3-carboxyl-1-sulfopropyl)-N-stearyl aspartate | Tetrasodium N-(3-carboxyl-1-sulfopropyl)-N-stearyl aspartate (CAS# 38916-42-6 ) is a useful research chemical. Synonyms: Aerosol 22; Alcopol R 540; Alcopol FL; Aero promoter 845; Procol CA 540. CAS No. 38916-42-6. Molecular formula: C26H43NNa4O10S. Mole weight: 653.646. | |
| TFC 007 | TFC-007 is a selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS), with high inhibitory activity against the H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used to construct a H-PGDS degrader inducer PROTAC(H-PGDS)-1, where TFC-007 binds to H-PGDS and Pomalidomide binds to cereblon. Synonyms: TFC-007; TFC 007; TFC007; N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 927878-49-7. Molecular formula: C27H29N5O4. Mole weight: 487.55. | |
| TFLLR-NH2 | TFLLR-NH2, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM. Synonyms: TFLLR amide; (Thr1)-TRAP-5 amide; (Thr1)-PAR-1 (1-5) amide (human); PAR-1-activating peptide; PAR-1-AP; L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide. Grades: 98%. CAS No. 197794-83-5. Molecular formula: C31H53N9O6. Mole weight: 647.81. | |
| TG101348 | Fedratinib is a potent and selective JAK2 inhibitor with IC50 value of 6 nM. It also exhibits inhibitory effects against FLT3 (IC50 = 25 nM), RET (IC50 = 17 nM) and JAK3 (IC50 = 169 nM). Synonyms: TG101348; TG 101348; TG-101348; SAR302503; SAR-302503; SAR 302503; Fedratinib; N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide. Grades: >98%. CAS No. 936091-26-8. Molecular formula: C27H36N6O3S. Mole weight: 524.68. | |
| TG 4-155 | TG 4-155 is a high affinity and selective EP2 receptor antagonist (KB = 2.4 and 34.5 nM for EP2 and DP1 receptors, respectively) displaying >500-fold selectivity over other prostanoid receptors. TG 4-155 inhibits butaprost-induced proinflammatory cytokine production, cell proliferation and invasion of PC-3 cells in vitro. Synonyms: TG4-155; TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155; (2E)-N-[2-(2-Methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1164462-05-8. Molecular formula: C23H26N2O4. Mole weight: 394.46. | |
| TH 1217 | TH 1217 is a potent dCTPase pyrophosphatase 1 inhibitor with IC50 value of 47 nM. Synonyms: 2-[4-[[5,6-Dichloro-2-methyl-4-nitro-1H-benzo[d]-imidazol-1-yl]methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione. Grades: ≥98% by HPLC. CAS No. 1862212-48-3. Molecular formula: C20H17BCl2N4O6. Mole weight: 491.09. | |
| TH-237A | TH-237A(meso-GS 164) is a novel neuroprotective agent exhibiting favorable permeation across the blood brain barrier. Synonyms: TH237A; TH 237A; TH237A. mesoGS 164. Grades: 0.98. CAS No. 935467-97-3. Molecular formula: C18H17F2NO3. Mole weight: 333.33. | |
| TH-257 | TH-257 is an effective inhibitor of LIMK1 and LIMK2. The IC50 values of LIMK1 and LIMK2 are 84 nM and 39 nM, respectively, and can be used as a chemical probe for LIMK1 and LIMK2. Synonyms: TH 257; TH257; N-Butyl-4-[(Phenylamino)Sulfonyl]-N-(Phenylmethyl)Benzamide; BCP31775; EX-A4475. Grades: 98%. CAS No. 2244678-29-1. Molecular formula: C24H26N2O3S. Mole weight: 422.5. | |
| TH-263 | TH-263 is a diarylsulfonamide derivative and can be used as a control for inactive analogs of TH-257, TH-255 and TH-251. Synonyms: TH263; Oprea1_207287; BCP32731; TH 263. Grades: 98%. CAS No. 313520-94-4. Molecular formula: C21H20N2O3S. Mole weight: 380.5. | |
| TH 5427 hydrochloride | TH 5427 is a potent nudix hydrolase 5 (NUDT5) inhibitor with IC50 value of 29 nM, displaying >650-fold selectivity for NUDT5 over NUDT1/MTH1. Synonyms: 7-[[5-(3,4-Dichlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-1,3-dimethyl-8-(piperazine-1-yl)-1H-purine-2,6-dione hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C20H20Cl2N8O3·HCl. Mole weight: 527.79. | |
| TH 5487 | TH 5487 is a selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with IC50 value of 342 nM. It inhibits OGG1 binding to 8-oxoG in DNA, suppressing proinflammatory gene expression in TNF-α stimulated lung epithelial cells in vitro, and also inhibiting proinflamatory gene expression and neutrophil recruitment in TNF-α-challenged mouse lungs in vivo. Synonyms: 4-(4-Bromo-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-N-(4-iodophenyl)-1-piperidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 2304947-71-3. Molecular formula: C19H18BrIN4O2. Mole weight: 541.18. | |
| Thailanstatin A | Thailanstatin A is a splicesosome inhibitor that acts via suppressing RNA-polymerase II. It is effective against cancers, and can be used as a payload for ADCs. Synonyms: 1,6-Dioxaspiro[2.5]octane-5-acetic acid, 7-[(1E,3E)-5-[(2S,3S,5R,6R)-5-[[(2Z,4S)-4-(acetyloxy)-1-oxo-2-penten-1-yl]amino]tetrahydro-3,6-dimethyl-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl]-8-hydroxy-, (3R,5S,7R,8R)-. Grades: 95%. CAS No. 1426953-21-0. Molecular formula: C28H41NO9. Mole weight: 535.63. | |
| Thalidomide 4'-ether-alkylC2-amine hydrochloride | Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a short C2 alkyl linker with terminal amine for covalent binding, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Thalidomide - linker 6. Grades: ≥95% by HPLC. CAS No. 2341840-99-9. Molecular formula: C15H16ClN3O5. Mole weight: 353.76. | |
| Thalidomide-O-amido-C6-NH2 (TFA) | Thalidomide-O-amido-C6-Amine trifluoroacetate is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions. Synonyms: Thalidomide-O-amido-C6-NH2 (TFA); Cereblon Ligand-Linker Conjugates 11 (TFA); E3 Ligase Ligand-Linker Conjugates 25 (TFA); Thalidomide-O-amido-C6-Amine Trifluoroacetate; N-(6-aminohexyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid. CAS No. 1950635-14-9. Molecular formula: C23H27F3N4O8. Mole weight: 544.48. | |
| Thalidomide-O-amido-C8-NH2 (TFA) | Thalidomide-O-amido-C8-NH2 (TFA) is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. Synonyms: E3 Ligase Ligand-Linker Conjugates 17. CAS No. 1950635-16-1. Molecular formula: C25H31F3N4O8. Mole weight: 572.53. | |
| Thalidomide-O-C4-NH2 hydrochloride | Thalidomide-O-C4-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C4 alkyl linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Thalidomide-linker 9. Grades: ≥95% by HPLC. CAS No. 2376990-29-1. Molecular formula: C17H20ClN3O5. Mole weight: 381.81. | |
| Thalidomide, propargyl | Thalidomide, propargyl is a cereblon-recruiting ligand consisting of an E3 ubiquitin ligase thalidomide conjugated to an alkyne linker ready for a target protein ligand. It has been used in PROTAC technology for target protein degradation. Synonyms: 2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione. Grades: ≥98%. CAS No. 2098487-39-7. Molecular formula: C16H12N2O5. Mole weight: 312.28. | |
| Theaflavin-3'-Gallate | Theaflavin-3'-gallate usually comes from the leaves of Camellia sinensis (L.) O. Kuntze. Theaflavin-3'-gallate, act as prooxidants and induce oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. Synonyms: [(2S,3R)-5,7-dihydroxy-2-[6,8,9-trihydroxy-5-oxo-3-[(2S,3R)-3,5,7-trihydroxychroman-2-yl]-11-bicyclo[5.4.0]undeca-1,3,6,8,10-pentaenyl]chroman-3-yl] 3,4,5-trihydroxybenzoate; THEAFLAVIN3GALLATE(3'-ISOMERICFORM); THEAFLAVINMONOGALLATEB; 3,4,5-Trihydroxybenzoic acid (2R,3R)-2-[8-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5-oxo-5H-benzocyclohepten-1-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester; Theaflavin 2B; Theaflavin-3'-Gallate (TF-3'-G); 3'-O-(3,4,5-Trihydroxybenzoyl). Grades: >98%. CAS No. 28543-07-9. Molecular formula: C36H28O16. Mole weight: 716.6. | |
| Thermopsine | Thermopsine can be isolated from the herbs of Thermopsis turkestanica. Synonyms: 7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,1,3,4,6,7,13,14,14a-octahydro-, (7R,14R,14aS)-; (7R)-7,7aβ,8,9,10,11,13,14-Octahydro-7β,14β-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one; 7,14-Methano-4H,6H-dipyrido[1,2-A:1',2'-E][1,5]diazocin-4-one, 7,7A,8,9,10,11,13,14-octahydro-, [7R-(7.alpha.,7A.alpha.,14.alpha.)]-; Nsc21725; Thermopsine,1-; (7R,14R,14aS)-1,3,4,6,7,13,14,14a-Octahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one; l-Thermopsine. Grades: >98%. CAS No. 486-90-8. Molecular formula: C15H20N2O. Mole weight: 244.33. | |
| Thiazolylacetylglycine Oxime | Thiazolylacetylglycine Oxime, is one of the novel compounds, used in the synthesis of Cefdinir, which is a third generation Cephalosporin antibiotic for oral administration and has a broad antibacterial spectrum over the gram positive and gram negative bacteria. Synonyms: (Z)-N-[ (2-Amino-4-thiazolyl) (hydroxyimino)acetyl]glycine; N-[ (2Z)- (2-Amino-4-thiazolyl) (hydroxyimino)acetyl]glycine. Grades: > 95%. CAS No. 178949-03-6. Molecular formula: C7H8N4O4S. Mole weight: 244.23. | |
| Thiazovivin | Thiazovivin is a selective, cell permeable small molecule that directly targets Rho-associated kinase (ROCK). In addition, Thiazovivin protects human embryonic stem cells (hESCs) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. This observation suggests that Thiazovivin promotes cell survival. In other studies Thiazovivin, in combination with inhibitors of the TGF-β receptor and MEK pathway, has shown to improve reprogramming efficiency by more than 200-fold. Uses: Reprogramming, self-renewal. Synonyms: Thiazovivin; 1226056-71-8; N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Thiazovivin (GMP); N-benzyl-2-(pyrimidin-4-ylamino)-1,3-thiazole-4-carboxamide; N-Benzyl-2-(pyrimidin-4-ylamino)-thiazole-4-carboxamide; N-(PHENYLMETHYL)-2-(4-PYRIMIDINYLAMINO)-4-THIAZOLECARBOXAMIDE; N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide; 4-THIAZOLECARBOXAMIDE, N-(PHENYLMETHYL)-2-(4-PYRIMIDINYLAMINO)-; SR-01000650935; C15H13N5OS; MLS006011152; SCHEMBL669856; CHEMBL3184878; DTXSID00673091; HMS3654N10; AMY36698; EX-A1693; HB3240; HY-13257G; MFCD16495823; s1459; AKOS016010502; CCG-267592; CS-0468; NCGC00187983-01; NCGC00187983-10; AC-28391; AS-16722; HY-13257; SMR004702926; CS-0626100; FT-0675156; SW219580-1; A25616; EN300-1719578; J-004834; SR-01000650935-1; SR-01000650935-2; Z2044738962; N-Benzyl-[2-(pyrimidin-4-yl)amino]t hiazole-4-carboxamide; N-Benzyl-2-[(pyrimidin-4-yl)amino]-1,3-thiazole-4-carboxamide. Grades: 0.98. CAS No. 1226056-71-8. Molecular formula: C15H13N5OS. Mole weight: 311.363. | |
| Thiocholine iodide | Thiocholine iodide is an important hydrolyzed product of acetylthio-choline iodide and could be used and one of the substrates of Cholinesterase. Uses: For research used only. Synonyms: (2-Mercaptoethyl)trimethylammonium iodide (7CI); Ammonium, (2-mercaptoethyl)trimethyl-, iodide (8CI); Ethanaminium, 2-mercapto-N,N,N-trimethyl-, iodide (9CI); Cholinethiol iodide; Thiocholine iodide; TChI. Grades: ≥ 95.0 %. CAS No. 7161-73-1. Molecular formula: C5H14INS. Mole weight: 247.14. | |
| Thioctate trometamol | Thioctate trometamol, a derivative of alpha-lipoic acid, displays potent antioxidant effects that aid in the management of diabetic neuropathy, alcoholic liver disease, and associated ailments. By boosting glucose metabolism and mitigating oxidative stress, this pharmaceutical compound facilitates the restoration of metabolic homeostasis. Conventionally available in tablet form for oral administration, Thioctate trometamol boasts excellent patient tolerance. Its striking antioxidant attributes are infinitely promising for disease mitigation in diverse clinical settings. Synonyms: Dexlipotam; Thioctic acid tromethamine; 5-(1,2-Dithiolaln-3-yl)-pentanoic acid tromethamine; Lipoic Acid Tromethamine Salt; 1,2-Dithiolane-3-pentanoic acid, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1). Grades: ≥95%. CAS No. 14358-90-8. Molecular formula: C8H14O2S2.C4H11NO3. Mole weight: 327.46. | |
| ThioLox | ThioLox is an inhibitor of 15-lipoxygenase-1 (15-LOX-1) with both anti-inflammatory and neuroprotective properties (IC50 value of 12 μM). 15-LOX-1 is involved in pro-inflammatory gene expression and central nervous system (CNS) disorders via mediation of oxidative stress and damage of mitochondrial membranes under hypoxic conditions. Ex vivo biological evaluation in precision-cut lung slices (PCLS) showed inhibition of pro-inflammatory gene expression and in vitro studies on neuronal HT-22 cells showed a strong protection against glutamate toxicity for this 15-LOX-1 inhibitor. Synonyms: ThioLox; 2-amino-N-butyl-5-phenylthiophene-3-carboxamide; 1202193-89-2; CHEMBL2360534; Thiophene A9; ThioLox-ThiopheneA9; MLS003675887; EX-A7757V; BDBM50206306; SMR002356509; HY-139196; CS-0181737; 2-amino-N-butyl-5-phenyl-thiophene-3-carboxamide. Grades: 99%. CAS No. 1202193-89-2. Molecular formula: C15H18N2OS. Mole weight: 274.38. | |
| Thiomyristoyl | Thiomyristoyl is a potent and selective inhibitor of SIRT2 with IC50 values of 0.028, 98, >200, and >200 μM for SIRT2, SIRT1, SIRT3, and SIRT5-7, respectively. It exhibits broad-spectrum anti-tumor activity against various cancer cells. Synonyms: TM; Benzyl N-[(2S)-1-anilino-1-oxo-6-(tetradecanethioylamino)hexan-2-yl]carbamate. Grades: ≥98%. CAS No. 1429749-41-6. Molecular formula: C34H51N3O3S. Mole weight: 581.9. | |
| Thiotolyl b-D-ribofuranoside | Thiotolyl b-D-ribofuranoside is a potent medicinal compound used in the biomedical industry. It exhibits promising therapeutic effects in treating certain diseases, such as cancer and viral infections. Its unique chemical structure allows for targeted delivery and enhanced efficacy. Synonyms: p-tolyl 1-thio-β-D-ribofuranoside; 4-methylphenyl 1-thio-β-D-ribofuranoside. Grades: ≥ 98%. CAS No. 1131610-84-8. Molecular formula: C12H14O5S. Mole weight: 270.3. | |
| THK5351 | THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain. THK5351 bound to AD hippocampal homogenates with high affinity (Kd = 2.9 nmol/L; Bmax = 368.3 pmol/g tissue). Synonyms: THK5351; THK 5351; THK-5351; (2S)-1-fluoro-3-[2-[6-(methylamino)pyridin-3-yl]quinolin-6-yl]oxypropan-2-ol; 18F-THK5351. CAS No. 1707147-26-9. Molecular formula: C18H18FN3O2. Mole weight: 327.35. | |
| THK5351 R enantiomer | THK5351 R enantiomer is an R enantiomer of THK5351 which can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain and bounds to AD hippocampal homogenates with high affinity (Kd = 2.9 nmol/L; Bmax = 368.3 pmol/g tissue). Synonyms: (2R)-1-fluoro-3-[2-[6-(methylamino)pyridin-3-yl]quinolin-6-yl]oxypropan-2-ol; THK5351 (R enantiomer). Molecular formula: C18H18FN3O2. Mole weight: 327.35. | |
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