BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Val-glu-pro-ile-pro-tyr | Synonyms: Valyl-glutamyl-prolyl-isoleucyl-prolyl-tyrosine; Vepipy; H-Val-Glu-Pro-Ile-Pro-Tyr-OH. CAS No. 94773-24-7. Molecular formula: C35H52N6O10. Mole weight: 716.82. |  |
| Valifenalate | Valifenalate(IR5885; Valiphenal), which is approved for application on high-value crops such as grapes, tomatoes and other vegetables, is effective against various types of mildew and is currently marketed primarily under the Valis moniker; insecticide agent. Synonyms: IR5885; IR 5885; IR-5885; Valiphenal. Grades: >98%. CAS No. 283159-90-0. Molecular formula: C19H27ClN2O5. Mole weight: 398.88. | |
| Valrubicin | Valrubicin (AD-32) is a chemotherapy drug used to treat bladder cancer. It is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder. Uses: Antineoplastic. Synonyms: Pentanoic Acid 2-[(2S,4S)-1,2,3,4,6,11-Hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl Ester; Antibiotic AD 32; N-Trifluoroacetyladriamycin 14-Valerate; NSC 246131; Valstar; Valtaxin; 2-Oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydro-2-tetracenyl]ethyl valerate. Grades: >98%. CAS No. 56124-62-0. Molecular formula: C34H36F3NO13. Mole weight: 723.64. | |
| Valsartan Desvaleryl Impurity | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Des(oxopentyl) Valsartan; N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine. CAS No. 676129-92-3. Molecular formula: C19H21N5O2. Mole weight: 351.41. | |
| Valsartan Ethyl Ester | An impurity of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Ethyl Ester. CAS No. 1111177-30-0. Molecular formula: C26H33N5O3. Mole weight: 463.58. | |
| Valsartan n-Propyl Impurity | Valsartan n-Propyl Impurity is an impurity in the synthesis of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: (S)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)butyramido)-3-methylbutanoic acid; Despentanoyl butanoyl valsartan; Valsartan USP Related Compound B. CAS No. 952652-79-8. Molecular formula: C23H27N5O3. Mole weight: 421.501. | |
| Valsartan Related Compound C | Valsartan Related Compound C is an intermediate of Valsartan. Valsartan is an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Synonyms: Valsartan Benzyl Ester; N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester; USP Valsartan Related Compound C. CAS No. 137863-20-8. Molecular formula: C31H35N5O3. Mole weight: 525.66. | |
| Valsartan USP Related Compound A | Valsartan USP Related Compound A is an R-enantiomer of Valsartan, an antagonist of angiotensin II receptor mainly used for the treatment of high blood pressure and congestive heart failure. Uses: The (r)-enantiomer of valsartan. Synonyms: (R)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid; D-Valsartan; ent-Valsartan. Grades: 95%. CAS No. 137862-87-4. Molecular formula: C24H29N5O3. Mole weight: 435.52. | |
| Vapreotide acetate (1:x) | Vapreotide is a synthetic somatostatin analog as a Somatotropin receptor antagonist. It can be used for the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Uses: Esophageal variceal bleeding. Synonyms: BMY41606; RC160; BMY 41606; RC 160; BMY-41606; RC-160; Octastatin; (4R,7S,10S,13S,16S,19R)-13-((1H-indol-3-yl)methyl)-N-((S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-(4-hydroxybenzyl)-7-isopropyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate. Grades: 98%. CAS No. 849479-74-9. Molecular formula: C57H70N12O9S2.xC2H4O2. Mole weight: 1191.43 (x=1). | |
| Vapreotide trifluoroacetate salt | Vapreotide is an analog of somatostatin and acts as a peptide neurokinin-1 receptor (NK1) antagonist (IC50 = 330 nM in a radioligand binding assay). It can be used for the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Synonyms: BMY 41606; Octastatin; RC 160. Grades: ≥95%. Molecular formula: C57H70N12O9S2·xCF3COOH. Mole weight: 1131.37. | |
| Varenicline dihydrochloride | Varenicline dihydrochloride is an α4β2 nicotinic acetylcholine receptor partial agonist. Varenicline is a prescription medication used for smoking cessation. Uses: Smoking cessation drug. Synonyms: 7,8,9,10-tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine dihydrochloride; Varenicline 2HCl; DB-076707; FT-0701597. Grades: > 98%. CAS No. 866823-63-4. Molecular formula: C13H15Cl2N3. Mole weight: 284.18. | |
| Vatiquinone | This active molecular has a para-benzoquinone structure and was developed for inherited mitochondrial diseases base on vitamin E. The mechanism of action of Vatiquinone involves increasing the synthesis of glutathione, optimizing metabolic control and so on. Now it is in Phase I for Gilles de la Tourette's syndrome, in Phase II for Friedreich's ataxia; Methylmalonic acidaemia; Mitochondrial disorders; Noise-induced hearing loss; Parkinson's disease; Rett syndrome Friedreich's ataxia; Methylmalonic acidaemia; Mitochondrial disorders; Noise-induced hearing loss; Parkinson's disease and Rett syndrome, in Phase III for Leigh disease. Uses: Inherited mitochondrial diseases. Synonyms: EPI743; EPI-743; EPI 743; alpha-Tocotrienol quinone;2-[(3R,6E,10E)-3-hydroxy-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione. Grades: 98%. CAS No. 1213269-98-7. Molecular formula: C29H44O3. Mole weight: 440.67. | |
| VE-1902 | VE-1902 is a novel and selective inhibitor of thrombin. Study in vivo and in vitro showed that VE-1902 inhibits thrombin via binding to it reversibly. Uses: The potential treatment of thrombus. Synonyms: VE-1902; VE 1902; VE1902. | |
| Vegita | Vegita is a metabolite of maneb, a fungicide. Synonyms: Hortocritt; Ethylenethiuramsulfide; Ethylenethiurammonosulfide; ETM(heterocycle); ETEM. Grades: 95%. CAS No. 33813-20-6. Molecular formula: C4H4N2S3. Mole weight: 176.28. | |
| Veledimex | Veledimex is used as an immunostimulant drug candidate. Uses: Veledimex is used as an immunostimulant drug candidate. Synonyms: AD-1001; AD1001; AD 1001; INXN-1001;INXN1001; INXN 1001; RG-115932; RG115932; RG 115932; N'-(3,5-dimethylbenzoyl)-N'-[(3R)-2,2-dimethylhexan-3-yl]-2-ethyl-3-methoxybenzohydrazide;(R)-N'-(3,5-dimethylbenzoyl)-N'-(2,2-dimethylhexan-3-yl)-2-ethyl-3-methoxybenzohydrazide. Grades: >98%. CAS No. 1093130-72-3. Molecular formula: C27H38N2O3. Mole weight: 438.61. | |
| Veliparib | Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. In HCT-116 and HT-29 cell lines, the ability of ABT-888 to synergize the effect of the anti-cancer agents, SN38 or oxaliplatin, was determined using the SRB assay. PARP activity was significantly reduced in samples treated with SN38 in combination with ABT-888 (>4 fold at 24 h). Uses: For research used only. Synonyms: (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; ABT888; ABT-888; ABT 888; Veliparib. Grades: 0.99. CAS No. 912444-00-9. Molecular formula: C13H16N4O. Mole weight: 244.298. | |
| Vepafestinib | Vepafestinib is a tyrosine kinase inhibitor and antineoplastic. Synonyms: vepafestinibum; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamide, 4-amino-N-[4-(methoxymethyl)phenyl]-7-(1-methylcyclopropyl)-6-[3-(4-morpholinyl)-1-propyn-1-yl]-. Grades: >98%. CAS No. 2129515-96-2. Molecular formula: C26H30N6O3. Mole weight: 474.6. | |
| Verteporfin | Verteporfin is a potent second-generation photosensitizing agent derived from porphyrin. It is used as a photosensitizer for photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. Verteporfin also suppresses the formation of autophagosome via targeting p62, which binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes. Synonyms: CL 318952; SC 95659; CL318952; SC95659; CL-318952; SC-95659; BPD-MA-A1; (4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid, monomethyl ester. Grades: 95%. CAS No. 129497-78-5. Molecular formula: C41H42N4O8. Mole weight: 718.81. | |
| Verubecestat | Verubecestat, an iminothiadiazine dioxide compound, is an oral BACE1 inhibitor originated by Merck & Co. It can bind significantly to β-secretase. Verubecestat has the potent effect to treat Alzheimer's disease and is currently in Phase III clinical trials. Uses: Alzheimer's disease. Synonyms: N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide; J1I0P6WT7T; Verubecestat; UNII-J1I0P6WT7T; J1I0P6WT7T; 1286770-55-5; Verubecestat [USAN]; Verubecestat (USAN/INN); GTPL8699; CHEMBL3301601; SCHEMBL10328722; SCHEMBL17507398; BDBM143220; example 25 (US8940748); SCH-900931; D10739; US8940748, 25; 2-Pyridinecarboxamide, N-(3-((5R)-3-amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoro-; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-1,2,5,6-tetrahydro-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide. Grades: 98%. CAS No. 1286770-55-5. Molecular formula: C17H17F2N5O3S. Mole weight: 409.41. | |
| (±)-Vesamicol hydrochloride | (±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (Ki = 2 nM) that blocks the loading of acetylcholine into synaptic vesicles of cholinergic nerve terminals. The inhibition by Vesamicol attenuates acetylcholine neuronal signaling without direct effecys on signaling mechanisms. Synonyms: AH5183 hydrochloride; AH 5183 hydrochloride; (±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride; 2-(4-Phenylpiperidino)cyclohexanol hydrochloride; Cyclohexanol, 2-(4-phenylpiperidino)-, hydrochloride. Grades: ≥99% by HPLC. CAS No. 120447-62-3. Molecular formula: C17H25NO.HCl. Mole weight: 295.85. | |
| VH 032-linker 6 | VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098799-80-3. Molecular formula: C31H42N4O7S. Mole weight: 614.75. | |
| Vibozilimod | Vibozilimodum is an immunomodulator. Synonyms: 4-Piperidinecarboxylic acid, 1-[[4-[5-[3-chloro-4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]-4-[(2-methoxyethoxy)methyl]-. Grades: >98%. CAS No. 1403232-33-6. Molecular formula: C29H36ClN3O5. Mole weight: 542.1. | |
| Vicine | Vicine is an alkaloid glycoside found mainly in fava beans. It is related to the loss of the enzyme glucose-6-phosphate dehydrogenase. Uses: Anti-arrhythmic. Synonyms: 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one; 2,6-Diamino-5-(β-D-glucopyranosyloxy)-4(1H)-pyrimidinone; 2,6-Diamino-5-(β-D-glucopyranosyloxy)pyrimidin-4-ol; Divicine β-D-glucopyranoside; Vicine[phytotoxin]; Vicioside; 2,6-Diamino-5-(beta-D-glucopyranosyloxy)-4(1H)-pyrimidinone. Grades: >98%. CAS No. 152-93-2. Molecular formula: C10H16N4O7. Mole weight: 304.26. | |
| Vidofludimus | Vidofludimus is an orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 134 nM for human DHODH. Phase 2. Synonyms: SC12267, SC 12267; SC-12267; 4SC-101; 4SC 101; 4SC101. Grades: 98%. CAS No. 717824-30-1. Molecular formula: C20H18FNO4. Mole weight: 355.36. | |
| Vildagliptin Carboxylic Acid Metabolite | Vildagliptin Carboxylic Acid Metabolite is a major metabolite of vildagliptin. Synonyms: N-(3-Hydroxytricyclo[3.3.1.1~3,7~]decan-1-yl)glycyl-L-proline. CAS No. 565453-40-9. Molecular formula: C17H26N2O4. Mole weight: 322.405. | |
| Vildagliptin Impurity 3 Trifluoroacetate | An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: Vildagliptin Carboxy Acid Metabolite Trifluoroacetate. CAS No. 565453-41-0. Molecular formula: C17H26N2O4. C2HF3O2. Mole weight: 436.43. | |
| Vildagliptin Impurity A | An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. CAS No. 565453-39-6. Molecular formula: C17H27N3O3. Mole weight: 321.4. | |
| Vildagliptin Impurity E hydrochloride | An impurity of Vildagliptin, an anti-hyperglycemic agent of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. Synonyms: Vildagliptin Impurity E HCl; 2-(3-Hydroxyadamantan-1-yl)-1-iminohexahydropyrrolo[1,2-a]pyrazin-4(1H)-one hydrochloride. Molecular formula: C17H25N3O2.HCl. Mole weight: 339.87. | |
| Vildagliptin Related Compound A | An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: Vildagliptin Imp.A; 2-Pyrrolidinecarbonitrile, 1-[2-(tricyclo[3.3.1.13,7]dec-1-ylamino)acetyl]-, (2S)-; Vildagliptin Deshydroxy Impurity; (S)-1-(2-((3R,5R,7R)-adamantan-1-ylamino)acetyl)pyrrolidine-2-carbonitrile. CAS No. 741657-02-3. Molecular formula: C17H25N3O. Mole weight: 287.4. | |
| Vinaginsenoside R3 | Vinaginsenoside R3 is a saponin composition of roots of Panax ginseng. Ginsengs have been not only used as therapeutic agents with tonic, sedative, anti-fatigue, and anti-gastric ulcer effect but also marketed as dietary supplements and raw materials of health food. Vinaginsenoside R3 is the first naturally occurring glycoside of dammarenediol 2. Synonyms: β-D-Glucopyranoside, (3β)?-20-(β-D-glucopyranosyloxy)?dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-;(3β)-20-(β-D-Glucopyranosyloxy)dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside. Grades: > 98%. CAS No. 156012-92-9. Molecular formula: C48H82O17. Mole weight: 931.15. | |
| Vina-ginsenoside R4 | Vina-ginsenoside R4 is a triterpenoid vina-ginsenoside standard extracted from Panax ginseng. Panax ginseng is a familiar herbal medicine which has been used as a tonic, sedative, anti-fatigue, or anti-gastric ulcer drug, and also has antidiabetic and antitumor activities. More than 40 ginsenosides have been identified, isolated and characterised till now. Synonyms: β-D-Glucopyranoside, (3β,?6α,?12β)?-20-(β-D-glucopyranosyloxy)?-6,?12-dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-. Grades: > 98%. CAS No. 156009-80-2. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Vinaginsenoside R8 | Vinaginsenoside R8 has the side chain with a migrated double bond on introduction of OH at C-25. Most of the known saponins have been isolated from other Panax spp., though gypenoside XVII and hemsloside Ma3 were not previously isolated from Araliaceae but from Cucurbitaceous plants. Synonyms: β-D-Glucopyranoside, (3β,?12β,?23E)?-20-(β-D-glucopyranosyloxy)?-12,?25-dihydroxydammar-23-en-3-yl 2-O-β-D-glucopyranosyl-. Grades: > 98%. CAS No. 156042-22-7. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Vinblastine sulfate | Vinblastine sulfate, also called cellblastin, derived from C. roseus, as a microtubule disrupter and antineoplastic agent, it binds tubulin and disrupts microtubule assembly and proper formation of the mitotic spindle, which leads to the assembly of microtubules and causing M phase-specific cell cycle arrest. Uses: Anticancer. Synonyms: cell pharm Brand of Vinblastine Sulfate; cellblastin; EG Labo Brand of Vinblastine Sulfate; Faulding Brand of Vinblastine Sulfate; Gastrozepin Brand of Vinblastine Sulfate; Gry Brand of Vinblastine Sulfate; Hexal Brand of Vinblastine Sulfate; Lemblastine; Lemery Brand of Vinblastine Sulfate; Lilly Brand of Vinblastine Sulfate; Sulfate, Vinblastine; Velban; Velbe; Vinblastin Hexal; Vinblastina Lilly; Vinblastine; Vinblastine Sulfate; Vinblastinsulfat-Gry; Vincaleukoblastine; Vinblastine sulfate; 143-67-9; C46H58N4O9H2SO4. Grades: >98%. CAS No. 143-67-9. Molecular formula: C46H58N4O9.H2SO4. Mole weight: 909.06. | |
| Vincetoxicoside B | Vincetoxicoside B is a natural compound isolated from Polygonum paleaceum Wall. It exhibits antifungal activity. Uses: Pharmacological experiment, content determination, identification, active filter. Synonyms: 3,5-Dihydroxy-2-(3,4-dihydroxyphenyl)-7-(α-L-rhamnopyranosyloxy)-4H-1-benzopyran-4-one; 7-(α-L-Rhamnopyranosyloxy)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-1-benzopyran-4-one; 7-(α-L-Rhamnopyranosyloxy)-3,5-dihydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one; Quercetin 7-rhamnoside; Vincetoxicoside B; Quercetin-7- O-α-L-rhaMnoside. Grades: >98%. CAS No. 22007-72-3. Molecular formula: C21H20O11. Mole weight: 448.38. | |
| Vindoline | Cas No. 2182-14-1. | |
| Vindolinine | Vindolinine is an alkaloid isolated from leaf extract (DA) of Catharanthus roseus (L.) G. Don. Synonyms: (2alpha, 3beta, 5alpha, 12beta, 19alpha, 20R)-6, 7-Didehydro-2, 20-cycloaspidospermidine-3-carbox ylic acid, methyl ester. Grades: 95%. CAS No. 5980-2-9. Molecular formula: C21H24N2O2. Mole weight: 336.435. | |
| Vinorelbine Ditartrate | Vinorelbine ditartrate, whose base is Vinorelbine, is a selective mitotic microtubule antagonist. It inhibits proliferation of Hela cells (IC50= 1.25 nM) and suppress microtubule dynamics (IC50 = 3.8 nM). Uses: Antitumor. Synonyms: (2β, 3β, 4β, 5α, 12R, 19α)-4-(Acetyloxy)-6, 7-didehydro-15-[(2R, 6R, 8S)-4-ethyl-1, 3, 6, 7, 8, 9-hexahydro-8-(methoxycarbonyl)-2, 6-methano-2H-azecino[4, 3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic acid methyl ester; 125317-39-7; Navelbine; KW-2307; Ambap125317-39-7; MFCD03613607; AB15572; NVB; Q-100110; (2B,3B,4B,5A,12R,19A)-4-(ACETYLOXY)-6,7-DIDEHYDRO-15-[(2R,6R,8S)-4-ETHYL-1,3,6,7,8,9-HEXAHYDRO-8-(METHOXYCARBONYL)-2,6-METHANO-2H-AZECINO[4,3-B]INDOL-8-YL]-3-HYDROXY-16-METHOXY-1-METHYLASPIDOSPERMIDINE-3-CARBOXYLIC ACID; 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2)salt]; 3',4'-DIDEHYDRO-4'-DEOXY-C'-NORVINCALEUKOBLASTINE [R-(R*,R*)-2-3-DIHYDROXYBUTANEDIOATE (1:2)SALT], 5'-NORANHYDRO; 3',4'-DIDEHYDRO-4'-DEOXY-C'-NORVINCALEUKOBLASTINE R-(R*,R*)-2-3-DIHYDROXYBUTANEDIOATE (1:2) SALT; 3',4'-DIDEHYDRO-4'-DEOXY-C'-NORVINCALEUKOBLASTINE R-(R*,R*)-2-3-DIHYDROXYBUTANEDIOATE SALT. Grades: >98%. CAS No. 125317-39-7. Molecular formula: C45H54N4O8.2C4H6O6. Mole weight: 1079.1. | |
| Vinyl isobutyrate | Vinyl isobutyrate, a versatile chemical compound, is widely utilized in the fine chemical and pharmaceutical industries. Acting as a fundamental substrate, it participates in the production of diverse drug classes, including potent antibiotics and anticancer agents, among others. Further, this compound finds extensive application in the creation of alluring fragrances and flavors due to its unique chemical attributes. Its multitude of practical uses and capabilities render it an essential component of the modern chemical industry. Synonyms: Vinylisobutyrate; Isobutyric acid, vinyl ester. Grades: 95%. CAS No. 2424-98-8. Molecular formula: C6H10O2. Mole weight: 114.14. | |
| Violanthin | Violanthin is a flavonoid showing antioxidant and antibacterial activities. Synonyms: Violanthin; 40581-17-7; C10196; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]chromen-4-one5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3S,4R,5R,6R)-3,4,5-trihydroxy -6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-me thyl-oxan-2-yl]chromen-4-one. Grades: 0.98. CAS No. 40581-17-7. Molecular formula: C27H30O14. Mole weight: 578.5. | |
| Vipadenant | Vipadenant is an adenosine A2 receptor antagonists used as an immunosuppressant. Synonyms: BG-14; CEB-4520; V2006; VER-11135; VER-A00-11; VER-A00049; VER-ADO-49; VR-2006. CAS No. 442908-10-3. Molecular formula: C16H15N7O. Mole weight: 321.34. | |
| Virstatin | Virstatin is an inhibitor of the virulence transcriptional activator ToxT of V. cholerae. It prevents expression of the two major V. cholerae virulence factors, cholera toxin (CT) and the toxin coregulated pilus, by inhibiting ToxT. Synonyms: Isodibut; 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid; 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid; 4-(N-(1,8-naphthalimide))-n-butyric acid; 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid. Grades: ≥98%. CAS No. 88909-96-0. Molecular formula: C16H13NO4. Mole weight: 283.28. | |
| Vismodegib | Vismodegib (GDC-0449) is a potent, novel and specific inhibitor of hedgehog with IC50 of 3 nM and also inhibitor of P-gp with IC50 of 3.0 μM. Synonyms: Code name: GDC-0449; GDC 0449; GDC0449; RG3616; RG 3616; RG-3616. trade name: Erivedge. Grades: 0.99. CAS No. 879085-55-9. Molecular formula: C19H14Cl2N2O3S. Mole weight: 421.292. | |
| Vitexin 2''-O-p-coumarate | Vitexin 2''-O-p-coumarate is a compound of the flavonoid class isolated from the seeds of Trigonella foenum-graecum. Vitexin 2''-O-p-coumarate promotes 2BS cell proliferation induced by H(2)O(2). Synonyms: [(2S,3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxyphenyl)prop-2-enoate. Grades: >98%. CAS No. 59282-55-2. Molecular formula: C30H26O12. Mole weight: 578.526. | |
| Vitexin-4''-O-glucoside | Vitexin-4''-O-glucoside is a flavonoid isolated from Crataegus pinnatifida Bunge. Synonyms: 4''-O-Glucosylvitexin; Vitexin 4''-O-glucoside. Grades: 98%. CAS No. 178468-00-3. Molecular formula: C27H30O15. Mole weight: 594.5. | |
| Vofopitant Dihydrochloride | The dihydrochloride salt form of Vofopitant, a tetrazole compound, has been found to be a neurokinin 1 antagonist that was once studied inbBipolar disorders as well as nausea and vomiting. Synonyms: Vofopitant dihydrochloride; 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoro-methyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S,3S)-;3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihy. Grades: 98%. CAS No. 168266-51-1. Molecular formula: C21H23F3N6O2HCl. Mole weight: 505.37. | |
| VO-OHpic | VO-OHpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) (IC50 = 35 nM), displaying selectivity for PTEN over cysteine-based phosphatases including SopB, MTM, PTPβ and SAC (IC50 = 588 nM, 4.03, 57.5 and >10 μM respectively). VO-OHpic has been shown to increase PIP2 and PIP3 levels, and Akt translocation in NIH/3T3 fibroblasts. Synonyms: (OC-6-45)-Aqua(3-hydroxy-2-pyridinecarboxylato-κ-N1,κO2)[3-(hydroxy-κO)-2-pyridinecarboxylato(2-)-κO2]oxovanadate(1-),hydrogen; 3-hydroxypyridine-2-carboxylic acid; oxido(oxo)vanadium. Grades: ≥98% by HPLC. CAS No. 675848-25-6. Molecular formula: C12H10N2O8V. Mole weight: 361.16. | |
| VO-Ohpic trihydrate | VO-Ohpic is a highly selective small-molecule inhibitor of phosphatase and tensin homologue deleted on chromosome 10 (PTEN). It is a specific vanadium-based inhibitor screened out from a range of synthesized vanadates and bpV complexes. Synonyms: VO-OHpic; VO OHpic; VOOHpic; VO-Ohpic trihydrate. Grades: >98%. CAS No. 476310-60-8. Molecular formula: C12H15N2O11V. Mole weight: 415.2. | |
| Vorinostat | Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM. Uses: Antineoplastic agents; histone deacetylase inhibitors. Synonyms: MK-0683, MK 0683, MK0683, SAHA, M344, CCRIS 8456, HSDB 7930, Vorinostat, suberoylanilide hydroxamic acid, Zolinza. Grades: >98%. CAS No. 149647-78-9. Molecular formula: C14H20N2O3. Mole weight: 264.3. | |
| Vosoritide | Vosoritide is a medicine used to treat achondroplasia. Grades: ≥95%. CAS No. 1480724-61-5. Molecular formula: C176H290N56O51S3. Mole weight: 4103. | |
| VPC 23019 | VPC 23019 is an aryl amide-containing S1P analog that acts as a competitive antagonist, inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells. Uses: Sphingosine-1-phosphate receptor antagonist. Synonyms: VPC23019; VPC-23019; (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester. Grades: ≥98%. CAS No. 449173-19-7. Molecular formula: C17H29N2O5P. Mole weight: 372.40. | |
| VRX-806 | VRX-806 is a novel nonnucleoside reverse transcriptase inhibitor (NNRTI) with potent in vitro activity against wild-type and NNRTI-resistant HIV-1. Synonyms: VRX-806; VRX 806; VRX806; AR-806; AR 806; AR806; RDEA-806; RDEA 806; RDEA806;4-[[2-[[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-3-chlorobenzoic acid. Grades: >98 %. CAS No. 1004523-72-1. Molecular formula: C24H18BrClN4O3S. Mole weight: 557.85. | |
| VT-1161 | VT-1161 is a 14-alpha demethylase inhibitor as a tetrazole antifungal agent originated by Viamet Pharmaceuticals. VT-1161 shows potent efficacy in treatment of dermatophytosis in a guinea pig model. Phase II clinical trials for the treatment of Onychomycosis and Vulvovaginal candidiasis is on-going. Uses: Onychomycosis; vulvovaginal candidiasis. Synonyms: VT 1161; VT1161; Oteseconazole. Grades: 98%. CAS No. 1340593-59-0. Molecular formula: C23H16F7N5O2. Mole weight: 527.40. | |
| VT-ME6 | VT-ME6 is a selective sphingosine kinase 2 inhibitor. VT-ME6 shows three-fold selectivity for SphK2 over SphK1. It has a quaternary ammonium group which is necessary for engaging key amino acid residues in the enzyme binding pocket.13,14. Synonyms: VT-ME6, VT-ME-6, VT-ME 6; Dimethyl-[4-(4-octyl-phenyl)-cyclohexyl]-propyl-ammonium iodide. Grades: 98%. CAS No. 1353880-00-8. Molecular formula: C25H44IN. Mole weight: 484.54. | |
| VTP-27999 | VTP-27999 is an alkyl amine Renin inhibitor. It is useful for Hypertension and End-Organ Diseases. Synonyms: VTP-27999; VTP 27999; VTP27999. Grades: >98%. CAS No. 942142-51-0. Molecular formula: C26H41ClN4O5. Mole weight: 525.08. | |
| VTP-27999 2,2,2-trifluoroacetate | VTP-27999 2,2,2-trifluoroacetate is an alkyl amine Renin inhibitor, useful for Hypertension and End-Organ Diseases. Synonyms: VTP-27999; VTP27999; VTP 27999. VTP-27999 HCl; VTP-27999 TFA. Grades: >98%. CAS No. 1013937-63-7. Molecular formula: C28H42ClF3N4O7. Mole weight: 639.1. | |
| VTP-27999 Hydrochloride | VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. Synonyms: VTP27999 Hydrochloride; VTP 27999 Hydrochloride. Grades: >98%. CAS No. 1264191-73-2. Molecular formula: C26H42Cl2N4O5. Mole weight: 561.54. | |
| VTP50469 | VTP50469 is a Menin-MLL interaction inhibitor, effective against MLL rearrangement and NPM1c+ leukemia. It has effective anti-leukemia activity. Grades: ≥98% by HPLC. CAS No. 2169916-18-9. Molecular formula: C32H47FN6O4S. Mole weight: 630.82. | |
| VU 0463271 | VU 0463271 is a potent and selective inhibitor of KCC2, which is a neuronal K-Cl cotransporter (IC50 = 61 nM). VU 0463271 exhibits >100-fold selectivity versus the Na-K-2Cl cotransporter 1 (NKCC1) and no activity against a panel of 68 GPCRs, ion channels and transporters. Synonyms: VU0463271; VU-0463271; VU 0463271; N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide. Grades: ≥98% by HPLC. CAS No. 1391737-01-1. Molecular formula: C19H18N4OS2. Mole weight: 382.5. | |
| VU-0483605 | VU-0483605, an isoindol derivative, has been found to be a mGluR1 positive allosteric modulator and probably be effective against schizophrenia. EC50: 356 and 390 nM for rat and human receptors, respectively. Synonyms: CHEMBL3628116; VU0483605, VU-0483605, VU 048360; AOB6248; SYN5042; AOB 6248; SYN 5042; AOB-6248; SYN-5042; 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide. Grades: 98%. CAS No. 1623101-11-0. Molecular formula: C20H10Cl3N3O3. Mole weight: 446.67. | |
| VU6001221 | VU6001221 is a choline transporter (CHT) inhibitor (IC50 value of 270 nM) with comparable potency for choline uptake inhibition as ML352, as well as improved PK and CNS penetration. For the first time, VU6001221 allowed evaluation of a CHT inhibitor in a standard preclinical rodent cognition model, namely novel object recognition (NOR). Synonyms: VU 6001221; VU-6001221. Grades: 98%. CAS No. 2002495-17-0. Molecular formula: C20H26ClN3O3. Mole weight: 391.89. | |
| VULM 1457 | VULM 1457 is an Acyl-CoA that acts as a cholesterol acyltransferase (ACAT) inhibitor. VULM 1457 has been shown to reduce cholesterol levels in the plasma and liver of diabetic-hypercholesterolemic rats. Synonyms: VULM 1457; VULM1457; VULM-1457; N-[2,6-bis(1-Methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea. Grades: ≥99% by HPLC. CAS No. 228544-65-8. Molecular formula: C25H27N3O3S. Mole weight: 449.57. | |
| VX-661 | VX-661 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used in combination with Ivacaftor in the treatment of cystic fibrosis. Synonyms: 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide; VX 661; VX661; Tezacaftor. Grades: 98%. CAS No. 1152311-62-0. Molecular formula: C26H27F3N2O6. Mole weight: 520.50. | |
| W123 | W123 is an analog of FTY720, a competitive antagonist of S1P1. Synonyms: 3-(2-(3-hexylphenylamino)-2-oxoethylamino) propanoic acid. Grades: ≥98%. CAS No. 1345982-24-2. Molecular formula: C17H26N2O3. Mole weight: 306.4. | |
| W-13 hydrochloride | W-13 hydrochloride is a calmodulin antagonist that inhibits calmodulin activated PDE activity with an IC50 of 68 μM. Synonyms: W-13 hydrochloride; W 13 hydrochloride; W13 hydrochloride; N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 88519-57-7. Molecular formula: C14H17ClN2O2S.HCl. Mole weight: 349.27. | |
| W140 trifluoroacetate salt | W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), binding to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W140 in supplemental material). Synonyms: W140 TFA salt; (S)-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (TFA salt); Phosphonic acid, [(3S)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-, mono(trifluoroacetate); 2,2,2-trifluoroacetic acid. Grades: ≥95%. CAS No. 909725-64-0. Molecular formula: C18H28F3N2O6P. Mole weight: 456.39. | |
| W146 | W146 is a potent and selective sphingosine-1-phosphate receptor (S1P1) antagonist (Ki = 18 nM) with no effect at S1P2, S1P3 or S1P5. W146 potentiates capillary leakage and restores lymphocyte egress in vivo. Synonyms: W146; W 146; W-146; [(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid; (R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid. Grades: ≥98% by HPLC. CAS No. 909725-61-7. Molecular formula: C16H27N2O4P. Mole weight: 342.37. | |
| W-54011 | W-54011 is a potent, specific high affinity C5a receptor antagonist (Ki = 2.2 nM). Uses: C5a receptor antagonist. Synonyms: W54011; W 54011; W-54011; N-[[4-(dimethylamino)phenyl]methyl]-7-methoxy-N-(4-propan-2-ylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide;hydrochloride. Grades: ≥95%. CAS No. 405098-33-1. Molecular formula: C30H36N2O2. HCl. Mole weight: 493.08. | |
| W-5 hydrochloride | W-5 hydrochloride is a calmodulin antagonist that inhibits Ca2+-calmodulin dependent PDE with an IC50 of 240 μM. Synonyms: W-5 hydrochloride; W 5 hydrochloride; W5 hydrochloride; N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride. CAS No. 61714-25-8. Molecular formula: C16H22N2O2S.HCl. Mole weight: 342.88. | |
| W-7 hydrochloride | W-7 hydrochloride is a calmodulin antagonist that inhibits Ca2+-calmodulin-dependent phosphodiesterase (IC50 = 28 μM) and myosin light chain kinase (IC50 = 51 μM). W-7 is used as a vascular relaxing agent. Uses: Vascular relaxing agent. Synonyms: W-7 hydrochloride; W-7 hydrochloride; W-7 hydrochloride; W-7 HCl; W 7 HCl; W7 HCl; N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 61714-27-0. Molecular formula: C16H21ClN2O2S.HCl. Mole weight: 377.33. | |
| W-9 hydrochloride | W-9 hydrochloride is a calmodulin antagonist that inhibits calmodulin-activated PDE activity with an IC50 of 72 μM. Synonyms: W-9 hydrochloride; W 9 hydrochloride; W9 hydrochloride; N-(6-Aminohexyl)-5-chloro-2-naphthalenesulfonamide hydrochloride; W-7 Isomer hydrochloride. CAS No. 69762-85-2. Molecular formula: C16H21ClN2O2S.HCl. Mole weight: 377.33. | |
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