BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| S0859 | S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(I) recovery (K i=1.7 mM). Synonyms: S0859; S-0859; S 0859. Grades: >98%. CAS No. 1019331-10-2. Molecular formula: C29H24ClN3O3S. Mole weight: 530.04. |  |
| S-110483 | S-110483 is a prostanoid EP4 receptor antagonist with immunomodulatory and analgesic activities. Human EP4 receptor binding assays showed a Ki value of 0.73 nmol/L for S-110483. Uses: The potential prevention of rheumatoid arthritis (ra). Synonyms: S-110483; S 110483; S110483. | |
| S 12 | S 12 is a survivin inhibitor that alters spindle formation, resulting in mitotic arrest (by disrupting metaphase at the G2/M stage) and apoptosis. It inhibits cell proliferation and tumor growth independently of p53 status. Uses: Antitumor agent. Synonyms: S12; NSC201630; MLS000029787; SMR000010018; S 12; NSC 201630; MLS 000029787; SMR 000010018; S-12; NSC-201630; MLS-000029787; SMR-000010018; 3-[2-(1,3-benzodioxol-5-yl)-2-oxoethyl]-5-bromo-3-hydroxy-1,3-dihydro-2H-indol-2-one. Grades: 99%. CAS No. 258264-62-9. Molecular formula: C17H12BrNO5. Mole weight: 390.18. | |
| (S)-(-)-1,2-epoxydecane | Synonyms: (-)-1,2-Epoxydecane. CAS No. 81623-66-7. Molecular formula: C10H20O. Mole weight: 156.26. | |
| S-17092 | S-17092, a thiazolidine derivative, has been found to be a prolyl endopeptidase inhibitor which could be effective in the treatment of cognition disorder and be probably be significant in studies of Alzheimer's and Parkinson's disease. It is still under Phase-I trial. Synonyms: S-17092; S 17092; S17092. [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone. Grades: 98%. CAS No. 176797-26-5. Molecular formula: C22H28N2O2S. Mole weight: 384.54. | |
| S186 | S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA). It is a new strontium-specific chelating agent. It has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China. Synonyms: S186; S 186; S-186. Grades: >98%. CAS No. 97759-16-5. Molecular formula: C5H13CaNNaO7P2+3. Mole weight: 324.17. | |
| S1P1 Agonist III | S1P1 Agonist III, a S1P1 agonist, has been found to induce the lymphocyte counts' reduction in circulating blood and have potentials in study of autoimmune diseases. IC50: 18 nM(EC50). Uses: S1p1 agonist iii is a s1p1 agonist that has been found to induce the lymphocyte counts' reduction in circulating blood and have potentials in study of autoimmune diseases. Synonyms: S1P1 Agonist III; CHEMBL1938952; 4088AH; BDBM50361891; IN2195; TC-G 1006; TC G 1006; TCG1006; TC G-1006; TC-G-1006. Grades: 98%. CAS No. 1324003-64-6. Molecular formula: C21H16F3N3O3. Mole weight: 415.37. | |
| S1PR-MO-1 | The modulator of sphingosine-1-phosphate receptor. Synonyms: Cyclobutanecarboxylic acid, 3-[[1-[4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]amino]-. CAS No. 1149727-61-6. Molecular formula: C25H29N3O3. Mole weight: 419.52. | |
| S 2101 | S 2101 is a LSD1 inhibitor (IC50 = 990 nM; Ki = 610 nM), displaying selectivity for LSD1 over MAO-B and MAO-A (Ki = 17 and 110 μM, respectively). Synonyms: (1R, 2S) -rel-2-[3, 5-Difluoro-2- (phenylmethoxy) phenyl]cycloprpanamine hydrochloride; HY-110277; S-2101; HY 110277; S 2101; HY110277; S2101. Grades: ≥98% by HPLC. CAS No. 1239262-36-2. Molecular formula: C16H15F2NO.HCl. Mole weight: 311.75. | |
| (S)-2-Amino-2-methyl-4-pentenoic acid | (S)-2-Amino-2-methyl-4-pentenoic acid, an analog of amino acid, serves as a versatile ligand for studying the ionotropic glutamate receptors, besides becoming a precursor for synthesizing diverse natural and unnatural amino acids. With its potential therapeutic effects on neural injury and epilepsy, this compound bears immense significance in the realm of neurological research. Synonyms: L-alpha-Allylalanine; 4-Pentenoicacid,2-amino-2-methyl-,(2R)-(9CI); L-α-Methylallylalanine; (S)-2-Amino-2-methyl-4-pentenoic acid; L-α-ALLYLALANINE; (R)-alpha-Allylalanine (>98%, >98%ee); H-alpha-All-L-Ala-OH; (R)-2-amino-2-methylpent-4-enoic acid. Grades: 98%. CAS No. 96886-56-5. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| (S)-2-Amino-3-(methylamino)propanoic acid hydrochloride | A neurotoxic glutamate agonist found in cyanobacteria. Synonyms: beta-N-Methylamino-L-alanine hydrochloride; L-BMAA Hydrochloride; (S)-2-amino-3-(methylamino)propanoic acid monohydrochloride; H-Dap(Me)-OH HCl; S-(+)-β-Methyl-α,β-diaminopropionic Acid Hydrochloride; BMAA Hydrochloride; β-Methylamino-L-alanine Hydrochloride (1:1); L-Alanine, 3-(methylamino)-, hydrochloride (1:1); 3-(Methylamino)-L-alanine hydrochloride (1:1). Grades: ≥95%. CAS No. 16012-55-8. Molecular formula: C4H11ClN2O2. Mole weight: 154.59. | |
| (S)-(+)-2-methylbutyl p-[(p-methoxybenzylidene)amino]cinnamate | (S)-(+)-2-methylbutyl p-[(p-methoxybenzylidene)amino]cinnamate, an active pharmaceutical intermediate, is a vital component in the pharmaceutical industry for synthesizing medications that alleviate pain and inflammation. Such disorders include osteoarthritis and arthritis, among others. Its significant role in medicinal chemistry, as a proficient synthesis intermediate, cannot be emphasized enough. Synonyms: (+)-2-METHYLBUTYL-P[(P-METHOXYBENZYLIDENE)AMINO]CINNAMATE; ACTIVE-AMYL P-ANISALAMINOCINNAMATE; ACT-AMYL P-ANISALAMINOCINNAMATE; (S)-(+)-2-METHYLBUTYL P-[(P-METHOXYBENZYLIDENE)AMINO]CINNAMATE; (+)-2-methylbutyl-4-methoxybenzilidine-4'-aminocinnamate; (+)-2-met. Grades: 95%. CAS No. 24140-30-5. Molecular formula: C22H25NO3. Mole weight: 351.44. | |
| S 32826 | S 32826 is an autotaxin inhibitor (IC50 = 9 nM) exhibiting similar inhibitory effects at all three autotaxin isoforms (α, β and γ). S 32826 displays no affinity for lysophosphatidic acid receptor 1 (LPA1) at concentrations up to 10 μM. It inhibits LPA release from adipocytes (IC50 = 90 nM). Synonyms: S32826; S-32826; S 32826; [4- (Tetradecanoylamino) benzyl]phosphonic acid disodium salt. Grades: ≥98% by HPLC. CAS No. 1103672-43-0. Molecular formula: C21H34NO4PNa2. Mole weight: 441.45. | |
| (S)-3-aminotetrahydrothiophene 1,1-dioxide hydrochloride | (S)-3-aminotetrahydrothiophene 1,1-dioxide hydrochloride is an important sulfur-containing heterocyclic compounds. It is widely used as building blocks in many agrochemicals, materials science and pharmaceuticals. Uses: (s)-3-aminotetrahydrothiophene 1,1-dioxide hydrochloride is widely used as building blocks in many agrochemicals, materials science and pharmaceuticals. Synonyms: (3S)-3-ThiophenaMine, tetrahydro-, 1,1-dioxide, hydrochloride;(3S)-1,1-dioxothiolan-3-amine hydrochloride. Grades: >98 %. CAS No. 935455-28-0. Molecular formula: C4H10ClNO2S. Mole weight: 171.65. | |
| (S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid | An intermediate in the synthesis of Lopinavir. Synonyms: (2S)-(1-Tetrahydropyramid-2-one)-3-methylbutanoic acid; (2S)-3-Methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid; J-501007. CAS No. 192725-50-1. Molecular formula: C9H16N2O3. Mole weight: 200.23. | |
| (S)-3-Methyl-2-phenylbutylamine | (S)-3-Methyl-2-phenylbutylamine is an intermediate in the process for producing optically active Flurbiprofen. Synonyms: (+)-2-Phenyl-3-MethylbutylaMine; (S)-PBA; (S)-β-Isopropylphenethylamine; (βS)-β-(1-Methylethyl)benzeneethanamine. Grades: 95 %. CAS No. 106498-32-2. Molecular formula: C11H17N. Mole weight: 163.26. | |
| (S)-3-Methylpiperidine hydrochloride | (S)-3-Methylpiperidine hydrochloride, a pharmacological precursor employed in the creation of numerous medicinal compounds spanning antihistamines, antiviral agents, and antipsychotics, is currently under examination for its possible efficacy in the remedy of neuropathic pain. Synonyms: (3S)-3-methylpiperidine hydrochloride; (S)-3-Methylpiperidine HCl. CAS No. 155797-02-7. Molecular formula: C6H14ClN. Mole weight: 135.63. | |
| S3QEL 2 | S3QEL 2 is a cell-permeable suppressor of superoxide production from complex III in the mitochondria. S3QEL-2 also protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia. It has no effects on normal electron flux or cellular oxidative phosphorylation (IC50 = 1.7 μM). Synonyms: S3QEL-2; S3QEL 2; S3QEL2; 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Grades: ≥98% by HPLC. CAS No. 890888-12-7. Molecular formula: C19H25N5. Mole weight: 323.44. | |
| (S)-4-amino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. CAS No. 2183841-60-1. Molecular formula: C10H17N3O5S3. Mole weight: 355.45. | |
| (S)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid | (S)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid, a promising pharmacological agent for treating hypertension and cardiovascular diseases, exerts its therapeutic effect via potent antagonism of the angiotensin receptor. By impeding the interactions between angiotensin II and its receptors, this compound inhibits vasoconstriction, thereby potentially leading to a decrease in blood pressure and mitigating the progression of associated pathologies. The unique chemical structure of (S)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid provides a strong foundation for future drug development efforts aimed at optimizing its pharmacological profile for clinical use. Synonyms: 5-({3-(Heptyloxy)-5-[(2S)-2-octanyloxy]benzyl}oxy)isophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[3-(heptyloxy)-5-[[(1S)-1-methylheptyl]oxy]phenyl]methoxy]-. Grades: ≥95%. Molecular formula: C30H42O7. Mole weight: 514.65. | |
| (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine | (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine, an important compound, is frequently utilized in scientific endeavors towards the development of medications for the treatment of diverse ailments, encompassing cancer and autoimmune diseases. Typically employed as a substrate for enzymes participating in the purine metabolic pathway, this substance exhibits notably high perplexity, owing to its intricate chemical composition. In addition, it boasts considerable burstiness, with some instances of relatively lucid nomenclature alongside more elaborative descriptions of its molecular properties. Uses: A novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder. Synonyms: S-adenosylhomocysteine; S-adenosyl-L-homocysteine; SAH; S-(5'-adenosyl)-L-homocysteine; AdoHcy. Grades: 98%. CAS No. 979-92-0. Molecular formula: C14H20N6O5S. Mole weight: 384.41. | |
| SA-4503 dihydrochloride | SA-4503 is a potent sigma receptor agonist. SA-4503 may have effects on depressive symptoms such as agitation, loss of interest, and impaired cognition, which are mediated by NMDA receptors. SA 4503 attenuates cocaine-induced hyperactivity and enhances methamphetamine substitution for a cocaine discriminative stimulus. Synonyms: SA 4503 dihydrochloride; 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride; SA4503 (dihydrochloride); Cutamesine dihydrochloride. Grades: 0.98. CAS No. 165377-44-6. Molecular formula: C23H34Cl2N2O2. Mole weight: 441.437. | |
| Sabizabulin | Sabizabulin is a tubulin polymerization inhibitor with anti-tumor activity. Synonyms: ABI-231; ABI 231; ABI231; VERU 111. Grades: >98%. CAS No. 1332881-26-1. Molecular formula: C21H19N3O4. Mole weight: 377.4. | |
| (S)-Acenocoumarol | Acenocoumarol is a short-lived oral anticoagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated in vitro. Synonyms: (S)-Acenocoumarin; (S)-Nicoumalone; (S)-(-)-Nicoumalone; 4-hydroxy-3-[(1S)-1-(4-nitrophenyl)-3-oxobutyl]chromen-2-one. Grades: ≥98%. CAS No. 66556-78-3. Molecular formula: C19H15NO6. Mole weight: 353.3. | |
| SAfit2 | SAfit2 is a potent inhibitor of FK506-binding protein 51 (FKBP51). SAfit2 has been studied as a potential therapeutic agent for the treatment of major depression, obesity and chronic pain. Synonyms: [(1R)-3-(3,4-dimethoxyphenyl)-1-[3-(2-morpholin-4-ylethoxy)phenyl]propyl] (2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate. Grades: ≥95%. CAS No. 1643125-33-0. Molecular formula: C46H62N2O10. Mole weight: 802.99. | |
| Sagittatoside A | Sagittatoside A is a natural compound isolated from traditional Chinese herb Yinyanghuo. Synonyms: Sagittatoside A; 118525-35-2; Icariin-A; 3-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one; SCHEMBL4982932; CHEBI:197154; HY-N0873; CS-3690; MS-31069. Grades: >98%. CAS No. 118525-35-2. Molecular formula: C33H40O15. Mole weight: 676.24. | |
| Saikosaponin B4 | Saikosaponin B4 is a saikosaponins isolated from Bupleurum chinese DC. It is a Saikosaponins standard to help analyse and resolve the activities of herbal medicines such as Sho-saiko-to. Sho-saiko-to, is a herbal medicine which prevents liver fibrosis and the development of preneoplastic lesions by directly inhibiting the activation of stellate cells. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: β-D-Galactopyranoside, (3β, ?4α, ?11α, ?16α)?-16, ?23, ?28-trihydroxy-11-methoxyolean-12-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-; (3β, 4α, 11α, 16α)-16, 23, 28-Trihydroxy-11-methoxyolean-12-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside. Grades: > 98%. CAS No. 58558-09-1. Molecular formula: C43H72O14. Mole weight: 813.02. | |
| Saikosaponin F | Saikosaponin F, a genuine glycoside, is a saikosaponins extracted from the methanolic extract of Bupleurum chinese DC. Saikosaponins is believed to be responsible for part of the pharmaceutical properties of Bupleuri Radix. Several saikogenins and their derivatives have anti-allergic activity, analgesic action, anti-inflammatory action, plasma cholesterol-lowering action, action for hepatic injuries, etc. Synonyms: β-D-Glucopyranoside, (3β,?16β)?-16,?28-dihydroxyolean-12-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1?4)?-O-[β-D-glucopyranosyl-(1?6)?]?-; (3β,16β)-16,28-Dihydroxyolean-12-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1?4)-O-[β-D-glucopyranosyl-(1?6)]-β-D-glucopyranoside. Grades: > 98%. CAS No. 62687-63-2. Molecular formula: C48H80O17. Mole weight: 929.1. | |
| Saikosaponin G | Saikosaponin G, a triterpene glycoside, is a saikosaponin which is believed to be responsible for part of the pharmaceutical properties of Bupleuri Radix. Bupleuri Radix, dried roots of Bupleurum spp. (Apiaceae), has been used as medicine in China for over 2000 years, and it is one of the most common components of Chinese traditional medicine prescriptions for the treatment of chronic hepatitis, kidney syndrome, inflammatory diseases, and ulcers of the digestive system. Synonyms: (3β,4α,16β)-16,23,28-Trihydroxyoleana-9(11),12-dien-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside. Grades: > 98%. CAS No. 99365-19-2. Molecular formula: C42H68O13. Mole weight: 780.98. | |
| Saikosaponin H | Saikosaponin H is a saikosaponins standard extracted from the Bupleuri Radix (Bupleurum spp. root) which is one of the most important crude drugs used inmany traditional Chinesemedicines (TCM). It helps analyse and resolve the activities of herbal medicines. Synonyms: β-D-Glucopyranoside, (3β,?16β)?-16,?28-dihydroxyoleana-11,?13(18)?-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1?4)?-O-[β-D-glucopyranosyl-(1?6)?]?-; (3β,16β)-16,28-Dihydroxyoleana-11,13(18)-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1?4)-O-[β-D-glucopyranosyl-(1?6)]-β-D-glucopyranoside. Grades: > 98%. CAS No. 91990-63-5. Molecular formula: C48H78O17. Mole weight: 927.12. | |
| Saikosaponin I | Saikosaponin I, extracted from the root of Bupleurum chinense DC, is a Saikosaponins standard to help analyse and resolve the activities of herbal medicines such as Sho-saiko-to. Sho-saiko-to is a herbal medicine which has been orally administered to patients with chronic liver disease in Japan and has been found to inhibit the development of hepatocellular carcinoma. Synonyms: (3beta,16beta)-16,28-Dihydroxyoleana-9(11),12-dien-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1?4)-O-[beta-D-glucopyranosyl-(1?6)]-beta-D-glucopyranoside. Grades: > 98%. CAS No. 103629-71-6. Molecular formula: C48H78O17. Mole weight: 927.12. | |
| Sal003 | Sal003 increases eIF2α phosphorylation status by blocking eIF2a phosphatases in cells. Synonyms: SAL-003; SAL 003; SAL003. Grades: >98%. CAS No. 1164470-53-4. Molecular formula: C18H15Cl4N3OS. Mole weight: 463.21. | |
| Salannal | Salannal is isolated from the root of M. azedarach L., which structure is elucidated by spectroscopic means. Grades: >98%. CAS No. 86160-86-3. Molecular formula: C34H44O10. | |
| Salbutamol EP Impurity B Hydrochloride | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Salbutamol EP Impurity B HCl; Salbutamol Impurity B HCl; Salbutamol Impurity B Hydrochloride; (1RS)-2-[(1,1-Dimethylethyl)amino]-1-(4-hydroxyphenyl)ethanol Hydrochloride. CAS No. 112337-52-7. Molecular formula: C12H19NO2.HCl. Mole weight: 245.75. | |
| Salbutamol Impurity G HCl | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: 2-[(1,1-Dimethylethyl)(phenylmethyl)amino]-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanone Hydrochloride; 2-(Benzyl-tert-butylamino)-4'-hydroxy-3'-(hydroxymethyl) acetophenone Hydrochloride; Benzylsalbutamon Hydrochloride. CAS No. 24085-08-3. Molecular formula: C20H25NO3.HCl. Mole weight: 363.88. | |
| Salbutamol Impurity I | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: α1-[[(1,1-Dimethylethyl)amino]methyl]-4-(phenylmethoxy)-1,3-benzenedimethanol; 1-(4-Benzyloxy-3-hydroxymethyl-phenyl)-2-(tert-butylamino)ethanol; 4-Benzyl Albuterol. Grades: > 95%. CAS No. 56796-66-8. Molecular formula: C20H27NO3. Mole weight: 329.44. | |
| Salbutamol Impurity N (Albuterol Dimer) | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Albuterol Dimer. Grades: > 95%. CAS No. 149222-15-1. Molecular formula: C26H40N2O5. Mole weight: 460.62. | |
| Salbutamol Impurity O | An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: 2-(tert-Butylamino)-1-(4-ethoxy-3-(hydroxymethyl)phenyl)ethanol; (±)-4-O-Ethyl Albuterol; Salbutamol EP Impurity O. Grades: > 95%. CAS No. 2387728-91-6. Molecular formula: C15H25NO3. Mole weight: 267.37. | |
| Salbutamon Hydrochloride | Salbutamon Hydrochloride is the hydrochloride form of Salbutamon, a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. Salbutamon is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: 2-[(1,1-Dimethylethyl)amino]-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethanone Hydrochloride; Albuterol Related Compound B. CAS No. 41489-89-8. Molecular formula: C13H20ClNO3. Mole weight: 273.76. | |
| Salubrinal | Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM. Synonyms: salubrinal|405060-95-9| (E) -3-phenyl -N- [2, 2, 2-tri chloro -1- (quinolin-8-yl carbamothioyl amino) ethyl ] prop-2-enamide |N- (2, 2, 2-tri chloro -1- (3- (quinolin-8-yl ) thioureido) ethyl ) cinnamamide | (2E)-3-phenyl -N- [2, 2, 2-tri chloro -1- [ [ (8-quinolinyl amino) thioxo methyl ] a mino] ethyl ]-2-propenamide |C21H17N4OSCl3|CHEMBL180 127|SCHEMBL6477826|SCHEMBL6477833|SC HEMBL17360638|CHEBI: 91873|DTXSID704 20852|CHEBI: 131923|HMS3413G22|HMS36 77G22|BCP06507|EX-A2153|MFCD00548612|s2923|STL253110|A KOS000525027|AKOS016042385|CCG-269541|3-Phenyl -N- [2, 2, 2-tri chloro -1- (3-quinolin-8-yl -thioureido) -ethyl ] -acryl amide |3-Phenyl -N- [2, 2, 2-tri chloro -1- [ [ (8-quinolinyl amino) thioxo methyl ] a mino] ethyl ]-2-propenamide |NCGC00159554-01|NCGC00159554-09|AC-33176|NS-05839|SW102000-2|C75050|Q7406268|BRD-A77299732-001-01-6|F0095-1218|N- (2, 2, 2-tri chloro -1- (3-quinolin-8-yl thioureido) ethyl ) cinnamamide | (E)-N- (2, 2, 2-tri chloro -1- (3- (quinolin-8-yl ) thioureido) ethyl ) cinnamamide | (2E)-3-phenyl -N- {2, 2, 2-tri chloro -1- [ (quinolin-8-yl carbamothioyl ) amino] ethyl } ac ryl amide | (E)-3-phenyl -N- [2, 2, 2. Grades: >98%. CAS No. 405060-95-9. Molecular formula: C21H17Cl3N4OS. Mole weight: 479.81. | |
| Salvianolic acid F | Salvianolic acid F is found in the roots of Salvia miltiorrhiza Bge. Synonyms: (E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoic acid. Grades: >98%. CAS No. 158732-59-3. Molecular formula: C17H14O6. Mole weight: 314.293. | |
| Sandenol | Sandenol is an organic compound used primarily as a fragrance because of its aroma which is similar to sandalwood oil. Synonyms: Isobornyl cyclohexanol; 3-(5,5,6-Trimethyl-2-norbornyl)cyclohexanol; 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexanol. Grades: 95%. CAS No. 3407-42-9. Molecular formula: C16H28O. Mole weight: 236.39. | |
| Sanggenol L | Sanggenol L is a pyranoflavanone found in the root bark of Morus alba L. Study shows that Sanggenol L has the therapeutic effect on ovarian cancer. Synonyms: 5,2'.4'-Trihydroxy-6''-methyl-6''-(4-methylpent-3-enyl)-pyrano[2'',3'':7,8]flavanone; 2-(2,4-dihydroxyphenyl)-5-hydroxy-8-methyl-8-(4-methylpent-3-enyl)-2,3-dihydropyrano[2,3-h]chromen-4-one. Grades: >98%. CAS No. 329319-20-2. Molecular formula: C25H26O6. Mole weight: 422.477. | |
| Sanggenone H | Sanggenone H is a compound of the flavonoid class found in the roots of Morus alba and Morus nigra. Synonyms: (2S)-5,7-dihydroxy-2-(5-hydroxy-2,2-dimethylchromen-8-yl)-2,3-dihydrochromen-4-one. Grades: >98%. CAS No. 86450-80-8. Molecular formula: C20H18O6. Mole weight: 354.358. | |
| Sapropterin dihydrochloride | Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency. Synonyms: BioMarin T 1401; Biopten; Kuvan; SUN 0588; Shiratori SN 0588; (6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride; Phenoptin; (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride; (6R)-Tetrahydrobiopterin hydrochloride; (6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride. Grades: >98%. CAS No. 69056-38-8. Molecular formula: C9H17Cl2N5O3. Mole weight: 314.17. | |
| SAR629 | SAR-629 is a Monoglyceride lipase (MGL) inhibitor and can also be known as 2-arachidonoylglycerol (2-AG) degradation inhibitor. MGL is a serine hydrolase which can hydrolyse 2-AG into arachidonic acid and glycerol. 2-AG is an endogenous ligand of cannabinoid receptors and it plays an important role in various physiological processes in the brain. Synonyms: (4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)(1H-1,2,4-triazol-1-yl)methanone. Grades: 98%. CAS No. 1221418-42-3. Molecular formula: C20H19F2N5O. Mole weight: 383.40. | |
| [Sar9,Met(O2)11]-Substance P | A selective agonist of tachykinin NK1 receptor. Synonyms: H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O2)-NH2; L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanyl-sarcosyl-L-leucyl-S,S-dioxo-L-methioninamide; (Sar(9))SP sulfone; 9-Sar-substance P sulfone; Sarcosyl(9)-substance P sulfone; 9-Sar-11-met(O2)-substance P; 9-Sarcosyl-11-methionine(O2)-substance P. Grades: ≥97% by HPLC. CAS No. 110880-55-2. Molecular formula: C64H100N18O15S. Mole weight: 1393.66. | |
| Sarolaner | Sarolaner is an antiparasitic agent. It is used as veterinary drug. Uses: Antiparasitic agent (veterinary use). Synonyms: PF-6450567; PF 6450567; PF6450567; (S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one. Grades: 98%. CAS No. 1398609-39-6. Molecular formula: C23H18Cl2F4N2O5S. Mole weight: 581.37. | |
| Satraplatin | Satraplatin, also known as JM216, is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. It has not yet received approval from the U.S. Food and Drug Administration. First mentioned in the medical literature in 1993, satraplatin is the first orally active platinum-based chemotherapeutic drug; other available platinum analogues-cisplatin, carboplatin, and oxaliplatin-must be given intravenously. It is made available in the United States jointly by Spectrum Pharmaceuticals and GPC Biotech under the name SPERA (Satraplatin Expanded Rapid Access). The drug has also been used in the treatment of lung and ovarian cancers. The proposed mode of action is that the compound binds to the DNA of cancer cells rendering them incapable of dividing. Synonyms: BMS-182751; BMS 182751; BMS182751; JM 216; JM216; JM-216. CAS No. 129580-63-8. Molecular formula: C10H24Cl2N2O4Pt. Mole weight: 500.28. | |
| Sauchinone | Sauchinone, coming from the herbs of Saururus chinensis(Lour.) Baill, is a useful adjunctive treatment for bacterial infection. Sauchinone inhibited oxidative stress, as assessed by stainings of 4-hydroxynonenal and nitrotyrosine: these events may have a role in its inhibitory effects on HSCs activation. Sauchinone attenuated CCl4-induced liver fibrosis and TGF-β1-induced HSCs activation, which might be, at least in part, mediated by suppressing autophagy and oxidative stress in HSCs. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes. Uses: Anti-inflammatory/antibacterial. Synonyms: (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one; (5aα, 7α, 8β, 8aβ, 14aS*, 14bβ)-5a, 6, 7, 8, 8a, 14b-Hexahydro-7, 8-dimethyl-5H-benzo[kl]bis[1, 3]dioxolo[4, 5-b:4', 5'-g]xanthen-5-one. Grades: >98%. CAS No. 177931-17-8. Molecular formula: C20H20O6. Mole weight: 356.36. | |
| Saxagliptin Cyclic Amidine Impurity | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one. Grades: > 95%. CAS No. 1350800-76-8. Molecular formula: C18H25N3O2. Mole weight: 315.42. | |
| Saxagliptin Impurity 15 | An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Synonyms: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo [3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carboxamide; 3-Descarbonitrile 3-Acetamido Saxagliptin. Grades: > 95%. CAS No. 1496712-39-0. Molecular formula: C18H27N3O3. Mole weight: 333.43. | |
| Saxagliptin Impurity 7 | An impurity of saxagliptin.Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Synonyms: (1aS,4S,6aR,7aS)-Hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione. Grades: > 95%. CAS No. 1350800-77-9. Molecular formula: C18H24N2O3. Mole weight: 316.4. | |
| Saxagliptin Keto Impurity | An impurity of Saxagliptin. Saxagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) used as a hypoglycemic drug. It was approved to treat type 2 diabetes. Synonyms: (1S,3S,5S)-2-((R)-2-amino-2-((1s,3R,5S,7S)-4-oxoadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Grades: 95%. Molecular formula: C18H23N3O2. Mole weight: 313.4. | |
| SB-203580 | SB 203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, also blocks PKB phosphorylation with IC50 of 3-5 μM. Uses: Enzyme inhibitors. Synonyms: SB203580; SB203580; SB 203580. Grades: >98%. CAS No. 152121-47-6. Molecular formula: C21H16FN3OS. Mole weight: 377.437. | |
| SB290157 trifluoroacetate | SB290157 trifluoroacetate is selective, high affinity, competitive C3a receptor antagonist (IC50 = 200 nM) suitable for use in animal models of inflammation. Synonyms: SB290157 trifluoroacetate; SB 290157 trifluoroacetate; SB-290157 trifluoroacetate; 5- (diaminomethylideneamino) -2-[[2- (2, 2-diphenylethoxy) acetyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid; IN1105. CAS No. 1140525-25-2. Molecular formula: C24H29F3N4O6. Mole weight: 526.51. | |
| SB 4 | SB 4 is a potent and selective BMP4 signaling agonist with EC50 value of 74 nM. It enhances canonical BMP signaling and activates SMAD-1/5/9 phosphorylation. Synonyms: 2-[[(4-Bromophenyl)methyl]thio]benzoxazole. Grades: ≥99% by HPLC. CAS No. 100874-08-6. Molecular formula: C14H10BrNOS. Mole weight: 320.2. | |
| SB431542 | SB-431542 is a potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. Uses: Reprogramming, differentiation. Synonyms: SB431542; SB-431542; SB 431542. Grades: 98%. CAS No. 301836-41-9. Molecular formula: C22H16N4O3. Mole weight: 384.39. | |
| SB525334 | SB-525334 is a potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM). It is ~4-fold less effective against ALK4 and inactive against ALK2, ALK3, and ALK6. Synonyms: SB525334; SB-525334; SB 525334. Grades: >98%. CAS No. 356559-20-1. Molecular formula: C21H21N5. Mole weight: 343.42494. | |
| SB 612111 | SB 612111 hydrochloride is a selective nociceptin/orphanin FQ (NOP) receptor antagonist (Ki value 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). It modulates the pronociceptive action of nociceptin in an acute pain model and enhances morphine action in morphine-tolerant animals and inhibits hyperalgesia in an inflammatory pain model. Synonyms: SB 612111 hydrochloride; SB612111 hydrochloride; SB-612111 hydrochloride; (5S,7S)-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol hydrochloride. Grades: 99%. CAS No. 371980-98-2. Molecular formula: C24H29Cl2NO. Mole weight: 418.4. | |
| SB 747651A dihydrochloride | SB 747651A dihydrochloride is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay). SB 747651A has been shown to inhibit MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells, and suppress IL-10 production in macrophages. Synonyms: SB747651A dihydrochloride; SB 747651A dihydrochloride; SB-747651A dihydrochloride; 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-4-piperidinyl-1H-imidazo[4,5-c]pyridine-7-methanamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1781882-72-1. Molecular formula: C16H22N8O.2HCl. Mole weight: 415.32. | |
| SB 747651A tetrahydrochloride | SB 747651A tetrahydrochloride is a potent and ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1) with an IC50 value of 11 nM. Synonyms: SB 747651A tetrahydrochloride; SB747651A tetrahydrochloride; SB-747651A tetrahydrochloride; 4-[1-ethyl-7-[(piperidin-4-ylamino)methyl]imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine tetrahydrochloride. Grades: 98%. CAS No. 2108968-31-4. Molecular formula: C16H22N8O.4HCl. Mole weight: 488.24. | |
| SBC-115076 | SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. Synonyms: SBC-115076; SBC 115076; SBC115076. Grades: 98%. CAS No. 489415-96-5. Molecular formula: C31H33N3O5. Mole weight: 527.62. | |
| SBE-β-CD | SBE-β-CD, also called as Sulfobutylether beta-cyclodextrin sodium, is a β-Cyclodextrin derivative with sulfobutyl ether groups and sodium ions substituted designed to optimize the drug properties. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation. Synonyms: SBE4-b-CyD; SBECD; Betadex Sulfobutyl Ether Sodium; Sulfobutyl Ether Beta-Cyclodextrin; Sulfobutyl Ether-Beta-Cyclodextrin; Sodium Sulphobutylether-Beta-Cyclodextrin. Grades: 95%. CAS No. 182410-00-0. Molecular formula: C70H119Na7O56S7. Mole weight: 2242.05. | |
| (S)-BoroLeu-(+)-Pinanediol trifluoroacetate | Synonyms: 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine, hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-, (alphaS,3aS,4S,6S,7aR)-, 2,2,2-trifluoroacetate (1:1); (S)-BoroLeu-(-)-Pinanediol-CF3COOH. CAS No. 477254-69-6. Molecular formula: C17H29BF3NO4. Mole weight: 379.2. | |
| (S)-Bromoenol lactone | (S)-Bromoenol lactone is an irreversible inhibitor of iPLA2&gamma. Synonyms: (S)-BEL; 6E-(bromoethylene)tetrahydro-3S-(1-naphthalenyl)-2H-pyran-2-one. Grades: ≥98%. CAS No. 478288-94-7. Molecular formula: C16H13BrO2. Mole weight: 317.2. | |
| SC144 | SC144 is an orally active small-molecule gp130 inhibitor (C50 = 0.72 μM). Synonyms: SC144; SC 144; SC-144. Grades: >98%. CAS No. 895158-95-9. Molecular formula: C16H11FN6O. Mole weight: 322.3. | |
| SC 19220 | SC 19220 is a selective EP1 receptor antagonist (IC50 = 6.7 μM for inhibition of [3H]-PGE2 binding to EP1 transfected COS cells). SC-19220 acts as a PGE2 antagonist in the EP1 receptor-mediated contraction of guinea pig trachea. Synonyms: SC-19220; SC 19220; SC19220. 8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-acetylhydrazide; N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide. Grades: ≥99% by HPLC. CAS No. 19395-87-0. Molecular formula: C16H14ClN3O3. Mole weight: 331.76. | |
| SC 26196 | SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays >100 fold selectivity over Δ5 and Δ9 desaturases (IC50 >200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model. Synonyms: α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; PF-o6341724; FT 0674530; SC 26196; FT0674530; SC26196; FT-0674530; SC-26196. Grades: ≥98% by HPLC. CAS No. 218136-59-5. Molecular formula: C27H29N5. Mole weight: 423.55. | |
| SC 51322 | SC 51322 is a potent EP1 prostanoid receptor antagonist (Ki = 13.8 nM) with analgesic properties in vivo. SC 51322 inhibits PGE2 signaling in a guinea pig ileum muscle strip assay with a pA2 value of 8.1. Synonyms: SC-51322; SC 51322; SC51322. 8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid hydrazide. Grades: ≥98% by HPLC. CAS No. 146032-79-3. Molecular formula: C22H20ClN3O4S. Mole weight: 457.93. | |
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