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Piperlotine C
Piperlotine C is isolated from the herbs of Piper nigrum L. Synonyms: 2-Propen-1-one, 1-(1-pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-, (2E). Grade: 0.975. CAS No. 886989-88-4. Molecular formula: C16H21NO4. Mole weight: 291.4.
Piperlotine D
Piperlotine D is isolated from the herbs of Piper nigrum L. Uses: Antiplatelet aggregation. Synonyms: (2Z)-1-(1-Pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one. Grade: > 95%. CAS No. 958296-13-4. Molecular formula: C16H21NO4. Mole weight: 291.4.
Pisatin
Pisatin is a phenolic compound synthesized by pea. Pisatin was the first phytoalexin to be purified and chemically identified. Synonyms: 3-hydroxy-7-methoxy-4',5'-methylenedioxy-chromanocoumarane; (6aS)-3-Methoxy-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-6aα(12aαH)-ol. Grade: >98%. CAS No. 20186-22-5. Molecular formula: C17H14O6. Mole weight: 314.3.
PNU159682-EDA
PNU159682-EDA is a drug-linker conjugate for ADC by using PNU159682 (a potent DNA topoisomerase II inhibitor), linked via EDA. Synonyms: EDA-PNU-159682; PNU-EDA. Grade: 90%. CAS No. 2255344-14-8. Molecular formula: C33H39N3O12. Mole weight: 669.68.
Pogostone
Pogostone, isolated from the herbs of Pogostemon cablin (Blanco) Benth, possesses potent anti-bacterial and anti-fungal activities and has been used for the quality control of essential oil of Pogostemon cablin. It could inhibit both gram negative bacteria (0.098-1 600 μg/ml) and gram positive bacteria (0.098-800 μg/ml). Besides, Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. Pogostone exhibited an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. Uses: Anti-bacterial/anti-fungal. Synonyms: Dhelwangin; 4-Hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one. Grade: >98%. CAS No. 23800-56-8. Molecular formula: C12H16O4. Mole weight: 224.26.
Polygonal
Polygonal isolated from the roots of Polygonum hydropiper. Synonyms: 3,4,4aα,5,6,7,8,8a-Octahydro-3α-hydroxy-5,5,8aβ-trimethyl-2-naphthalenecarbaldehyde; (3R,4aS,8aR)-3-Hydroxy-5,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahyd ro-2-naphthalenecarbaldehyde. Grade: 97.5%. CAS No. 72537-20-3. Molecular formula: C14H22O2. Mole weight: 222.3.
Polypodine B
Polypodine B is a steroid that can be isolated from Leuzea carthamoides, displaying embryotoxicity. Synonyms: Polypodin B; 5-Hydroxyecdysterone; 2beta,3beta,5beta,14,20,22R,25-Heptahydroxycholest-7-en-6-one; (2beta,3beta,5beta,22R)-2,3,5,14,20,22,25-heptahydroxycholest-7-en-6-one; Ajugasterone A. Grade: 98%. CAS No. 18069-14-2. Molecular formula: C27H44O8. Mole weight: 496.63.
Pomolic acid
Pomolic acid is a captivating natural compound, boasting intriguing prospects in the esteemed biomedical research of afflictions, encompassing the domains of cancer, neurodegenerative infirmities and cardiovascular incongruities. Synonyms: 3β,19-Dihydroxy-5α-urs-12-en-28-oic acid; 3β,19-Dihydroxyurs-12-en-28-oic acid; 3β,19α-Dihydroxyurs-12-ene-28-oic acid; Benthamic acid; Urs-12-en-28-oic acid, 3,19-dihydroxy-, (3β)-; Randialic acid A. CAS No. 13849-91-7. Molecular formula: C30H48O4. Mole weight: 472.71.
Pomolic acid 28-O-β-D-glucopyranosyl ester
Pomolic acid 28-O-beta-D-glucopyranosyl ester is a natural triterpenoid found in the root of Sanguisorba officinalis. Synonyms: 1-O-[(3β)-3,19-Dihydroxy-28-oxours-12-en-28-yl]-β-D-glucopyranose. Grade: >96%. CAS No. 83725-24-0. Molecular formula: C36H58O9. Mole weight: 634.9.
Ponicidin
Ponicidin is a natural diterpenoid compound found in the herbs of Isodon japonicus. Ponicidin shows immunoregulatory and anti-inflammatory functions. Ponicidin also exhibits the activities of anti-viral, anti-leukemi and anti-cancer. Synonyms: Rubescensin B. Grade: >98%. CAS No. 52617-37-5. Molecular formula: C20H26O6. Mole weight: 362.42.
Potassium (Bromomethyl)trifluoroborate
Organotrifluoroborate involved in: Suzuki-Miyaura cross-coupling reactions; Synthesis of functionalized ethyltrifluoroborates; SN2 displacement with alkoxidesOrganotrifluoroborates as versatile and stable boronic acid surrogates; Versatile starting material for preparation of a variety of functionalized substrates for Suzuki coupling. Synonyms: Potassium bromomethyltrifluoroborate. Grade: 90%. CAS No. 888711-44-2. Molecular formula: CH2BrF3BK. Mole weight: 200.84.
p-Phlorizin
Trilobatin, coming from the herbs of Lithocarpus pachyphyllus, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway. It increased superoxide dismutase (SOD) activity. Besides, Trilobatin is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect. Uses: Anti-inflammatory. Synonyms: 1-[4-(β-D-Glucopyranosyloxy)-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; p-Phloridzin; Phloretin 4'-glucoside; Phloretin 4'-β-D-glucoside; Phloretin-4-O-glycoside; Phloretin-4'-O-β-D-glucopyranoside; Phloretine-4'-glucoside; Prunin dihydrochalcone; Trilobatin. Grade: >98%. CAS No. 4192-90-9. Molecular formula: C21H24O10. Mole weight: 436.41.
Pregn-5-ene-3β,17α,20S-triol
Pregn-5-ene-3β,17α,20S-triol is a metabolite of Pregnenolone. Synonyms: (3β,17α,20S)-Pregn-5-ene-3,17,20-triol; delta 5-Pregnenetriol. Grade: 98.0%. CAS No. 903-67-3. Molecular formula: C21H34O3. Mole weight: 334.5.
Prerubialatin
Prerubialatin is a natural compound isolated from the herbs of Rubia cordifolia, being a precursor of rubialatins A and B. Synonyms: Prerubialatin; 1667718-89-9. CAS No. 1667718-89-9. Molecular formula: C27H20O7. Mole weight: 456.45.
Primeverose
Primeverose is a natural compound which can be isolated from the genus Primula. Synonyms: 6-(b-D-Xylosido)-D-glucose; 6-O-β-D-Xylopyranosyl-D-glucose; Xyl(b1-6)aldehydo-Glc; 6-(β-D-Xylosido)-D-glucose; (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)hexanal. Grade: 98%. CAS No. 26531-85-1. Molecular formula: C11H20O10. Mole weight: 312.27.
prim-O-Glucosylangelicain
prim-O-Glucosylangelicain is isolated from the roots of Cimicifuga foetida L. Synonyms: (S)7-[(beta-D-Glucopyranosyloxy)methyl]-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-5H-furo[3,2-g][1]benzopyran-5-one. Grade: >95%. CAS No. 85889-15-2. Molecular formula: C21H26O11. Mole weight: 454.42.
Prionidipene A
Prionidipene A, a promising chemical compound, exhibits therapeutic potential in treating neurological disorders including Alzheimer's disease. This inhibitor of the beta-site amyloid precursor protein cleaving enzyme curtails the production of amyloid beta peptides, an established hallmark of Alzheimer's disease. Interestingly, research proposes that Prionidipene A reduces amyloid beta levels in the brain, which in turn has therapeutic implications. Moreover, improved cognitive function was noted, suggesting that this compound could be a pivotal stepping stone in developing novel therapeutics for Alzheimer's disease. Grade: > 95%. CAS No. 2199455-72-4. Molecular formula: C21H26O3. Mole weight: 326.43.
(Pro3)-Gastric Inhibitory Polypeptide (human)
(Pro3)-Gastric Inhibitory Polypeptide (human) is an antagonist of GIP. Synonyms: (Pro3)-GIP (human); H-Tyr-Ala-Pro-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH; L-tyrosyl-L-alanyl-L-prolyl-glycyl-L-threonyl-L-phenylalanyl-L-isoleucyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-L-alanyl-L-methionyl-L-alpha-aspartyl-L-lysyl-L-isoleucyl-L-histidyl-L-glutaminyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-asparagyl-L-tryptophyl-L-leucyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysyl-glycyl-L-lysyl-L-lysyl-L-asparagyl-L-alpha-aspartyl-L-tryptophyl-L-lysyl-L-histidyl-L-asparagyl-L-isoleucyl-L-threonyl-L-glutamine. Grade: ≥95%. CAS No. 299898-52-5. Molecular formula: C226H338N60O64S. Mole weight: 4951.60.
(Pro8)-Oxytocin
(Pro8)-Oxytocin is the L8P variant of oxytocin produced by the Cebidae family of New World monkeys. Its intranasal application, binding to OT and AVP V1 receptors, enhances parental behavior in rats. Synonyms: (Pro8)-Vasotocin; H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Pro-Gly-NH2 (Disulfide bridge: Cys1-Cys6). CAS No. 24327-19-3. Molecular formula: C42H62N12O12S2. Mole weight: 991.15.
Procumbide
Procumbide is an iridoid compound found in herbs of Andrographis paniculata. Procumbide exhibits anti-inflammatory activity. Uses: Anti-inflammatory. Synonyms: [(1S)-1,4a,5,6,7,7aα-Hexahydro-4aα,5β-dihydroxy-7-methyl-6α,7α-epoxycyclopenta[c]pyran-1α-yl]β-D-glucopyranoside; [[(1S)-1,4a,5,6,7,7aα-Hexahydro-6α,7α-epoxy-7-methyl-4aα,5β-dihydroxycyclopenta[c]pyran]-1-yl]β-D-glucopyranoside. Grade: >96%. CAS No. 20486-27-5. Molecular formula: C15H22O10. Mole weight: 362.3.
Procyanidin A1
Procyanidin A1 is found in cinnamon and is extracted from the herbs of Daemonorops draco. It is an epicatechin-(2β→7,4β→8)-catechin dimer and is potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone. It inhibits LDL oxidation with the IC50 value of 0.94 uM. It also inhibits degranulation downstream of protein kinase C activation or Ca2? influx from an internal store in RBL-2H3 cells. It shows antiallergic effects. Synonyms: Proanthocyanidin A1; Epicatechin-(2b->7,4b->8)-catechin; (2R,3S,8S,14R,15R)-2,8-Bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol. Grade: 97.5%. CAS No. 103883-03-0. Molecular formula: C30H24O12. Mole weight: 576.50.
Procyanidin A2
(+)-Proanthocyanidin A2 is a polyphenol oxidase (PPO) substrates isolated from grape seeds (Vitis vinifera L). Proanthocyanidins represent one of the major groups of plant polyphenols. A2 could isolated from the acetone-water extract (7:3, v/v) of horse chestnut seed shells (Aesculus hyppocastanum), after extraction with ethyl acetate, by combined LH-20 chromatography and TLC on Silicagel 60 plates. Synonyms: 8,?14-Methano-2H,?14H-1-benzopyrano[7,?8-d]?[1,?3]?benzodioxocin-3,?5,?11,?13,?15-pentol, 2,?8-bis(3,?4-dihydroxyphenyl)?-3,?4-dihydro-, (2R,?3R,?8S,?14R,?15R)?-; 8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol, 2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, [2R-(2α,3α,8β,14β,15R*)]-; (2R,3R,8S,14R,15R)-2,8-Bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol; (+)-Epicatechin-(4β-8,2β-O-7)-epicatechin; Dimeric catechin. Grade: > 98%. CAS No. 41743-41-3. Molecular formula: C30H24O12. Mole weight: 576.50.
Procyanidin B2
Procyanidin B2 has been shown to inhibit the formation of the advanced glycation end-products pentosidine, carboxymethyllysine (CML), and methylglyoxal (MGO). Uses: Anti-hypertension. Synonyms: PROCYANIDIN B2; 4,8'-BI-[(+)-EPICATECHIN]; EPICATECHIN(4BETA->8)EPICATECHIN; EPICATECHIN(4B-8)EPICATECHIN; CIS,CIS'-4,8'-BI(3,3',4',5,7-PENTAHYDROXYFLAVANE); 4,8-Bi-2H-1-benzopyran-3,3,5,5,7,7-hexol, 2,2-bis(3,4-dihydroxyphenyl)-3,3,4,4-tetrahydro-, (2R,2R,3R,3R,4R)-; PROCYANIDIN B2(RG); PROCYANIDINDIMERB2. Grade: >98%. CAS No. 29106-49-8. Molecular formula: C30H26O12. Mole weight: 578.52.
Procyanidin C1
Procyanidin C1 is extracted from the fruits of Vitis vinifera L. It is a B type proanthocyanidin and found in grape. It belongs to a polyphenol flavonoid epicatechin trimer. It can decrease cytokine production of mast cells and Fc epsilon RI-mediated degranulation in vitro dose-dependently. It inhibits ROS generation in stimulated mast cells and the tyrosine phosphorylation of Syk and linker for activation of T cells. It may be used for the treatment of cardiovascular diseases and may be useful as a lead compound to develop inhibitors of cancer metastasis and other diseases related to EMT. It has HIV-related, antioxidant and anti-inflammatory effects. It also inhibits the activity of 15-lipoxygenase and α-glucosidase. It could scavenge 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radicals. Synonyms: Procyanidol C1; (2R,2'R,2''R,3R,3'R,3''R,4R,4'S)-2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-[4,8':4',8''-ter-2H-1-benzopyran]-3,3',3'',5,5',5'',7,7',7''-nonol; Proanthocyanidin C1; Cinnamtannin A1; [Epicatechin-(4beta->8)]2-epicatechin. Grade: 98%. CAS No. 37064-30-5. Molecular formula: C45H38O18. Mole weight: 866.77.
(Prolyl-hydroxylprolyl-glycine)10
(Prolyl-hydroxylprolyl-glycine)10 is a heterotetramer and a key enzyme for collagen synthesis. Synonyms: (Pro-hyp-gly)10. CAS No. 40350-90-1. Molecular formula: C120H172N30O41. Mole weight: 2690.8.
Propargyl-NHS Ester
Propargyl-NHS ester is an indispensable small molecule tool in the biomedical field and is a key coupling agent that promotes bioconjugation reactions. This compound labels a range of biomolecules including proteins and peptides, facilitating their unambiguous identification and meticulous monitoring. With its sheer versatility, Propargyl-NHS Ester coordinates a range of tasks, including drug delivery systems, diagnostics and targeted therapies. Synonyms: Propargyl-PEG1-NHS ester; 2,5-dioxopyrrolidin-1-yl 3-(prop-2-ynyloxy)propanoate; N-Succinimidyl 3-(propargyloxy)propionate; Propargyl-N-hydroxysuccinimidyl ester. Grade: 95% by NMR. CAS No. 1174157-65-3. Molecular formula: C10H11NO5. Mole weight: 225.20.
20S-Protopanaxatriol (g-PPT), a dammarane-type tetracyclic terpene sapogenin, may be used to study its binding to and modulation of cell function via glucocortoid (GR) and oestrogen (ER) receptors. Protopanaxatriol can be used in health products. Synonyms: 20(S)-APPT; g-PPT. Grade: >98%. CAS No. 34080-08-5. Molecular formula: C30H52O4. Mole weight: 476.73.
Protopine
Protopine is an alkaloid isolated from the tubers of Corydalis yanhusuo W.T.Wang. It shows weak spasmolytic, smooth muscle stimulant activities. Uses: Bactericidal; sedative; antihypertensive. Synonyms: 7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one; Biflorine. Grade: 98%. CAS No. 130-86-9. Molecular formula: C20H19NO5. Mole weight: 353.4.
Protosappanin B
Protosappanin B is a natural compound found in the heart wood of Caesalpinia sappan L. Protosappanin B exhibits antitumor and anti-oxidant activity that can inhibit the oxidation of linoleic acid. Uses: Antitumor, anti-oxidant. Synonyms: (-)-Protosappanin B; 6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol, 7,8-dihydro-7-(hydroxymethyl)-, (7S,12aS)-. Grade: >95%. CAS No. 102036-29-3. Molecular formula: C16H16O6. Mole weight: 304.30.
Przewalskin
Przewalskin is isolated from the roots of Salvia miltiorrhiza. Uses: Antitumor activity. Synonyms: (5ξ,7β)-13-Methyl-7,17-epoxypodocarpa-8,11,13-trien-12-ol. Grade: 98%. CAS No. 119400-87-2. Molecular formula: C18H24O2. Mole weight: 272.4.
(p-SCN-Bn)-NOTA
(p-SCN-Bn)-NOTA is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: NOTA-1; 1H-1,4,7-Triazonine-1,4,7-triacetic acid, hexahydro-2-[(4-isothiocyanatophenyl)methyl]-; p-SCN-Bn-NOTA; Hexahydro-2-[(4-isothiocyanatophenyl)methyl]-1H-1,4,7-triazonine-1,4,7-triacetic acid; 2-(4-Isothiocyanatobenzyl)-1,4,7-triazacyclonane-1,4,7-triacetic acid; 2-(p-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid. Grade: ≥95%. CAS No. 147597-66-8. Molecular formula: C20H26N4O6S. Mole weight: 450.51.
Pseudoginsenoside-F11
Pseudoginsenoside-F11 is extracted from the roots of Panax ginseng C. A. Mey. It antagonized the memory dysfunction induced by scopolamine. It has been shown to antagonize the behavioral actions of morphine. It may block the development of morphine-induced behavioral sensitization via its effect, at least partially, on the glutamatergic system in the medial prefrontal cortex (mPFC). Uses: An oxotillol-type ginsenoside which displayes neuroprotective activity. Synonyms: (20S,24R)-6α-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)-20,24-epoxy-5α-dammarane-3β,12β,25-triol; (24R)-Pseudoginsenoside F11; [(24R)-20,24-Epoxy-3β,12β,25-trihydroxy-5α-dammaran-6α-yl] 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside; Pseudoginsenoside F11; 17β-[[(2S)-2β-Methyl-5α-(1-hydroxy-1-methylethyl)tetrahydrofuran]-2-yl]-3β,12β-dihydroxy-4,4,8β,10β,14α-pentamethyl-5α-gonane-6α-yl 2-O-α-L-rhamnopyranosyl-β-D-glucopyranoside; Ginsenoside A1; (3β,6α,12β,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside; 24(R)-Pseudoginsenoside F11. Grade: >98%. CAS No. 69884-00-0. Molecular formula: C42H72O14. Mole weight: 801.01.
Pseudolaric acid B
Pseudolaric acid B (PAB), which comes from the bark of Pseudolarix kaempferi Gordon, has diverse effects that are relevant to cancer therapy, including apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo. pseudolaric acid B can trigger apoptosis by decreasing Bcl-2 levels and activating caspase-3 protease. The future development of PAB as a cancer therapeutic is ongoing. Besides, PAB significantly suppressed proliferation of DU145 cells in a dose-dependent manner without obvious cytotoxicity. PAB may inhibit growth of HRPC DU145 cells and induce apoptosis through ROS generation and Bcl-2 degradation via the activation of the ubiquitin-proteasome pathway. Uses: Antifungal/antifertility. Synonyms: PLAB; 1H-4,9a-Ethanocyclohepta[c]pyran-7-carboxylicacid,4a-(acetyloxy)-3-[(1E,3E)-4-carboxy-1,3-pentadien-1-yl]-3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methyl ester, (3R,4S,4aS,9aR)-; Pseudolarix acid B; Pseudolaric acid. Grade: >98%. CAS No. 82508-31-4. Molecular formula: C23H28O8. Mole weight: 432.46.
Pseudolaric acid D
Pseudolaric acid D is isolated from the root bark of Pseudolarix amabilis. Synonyms: ent-18-hydroxy-15-kauren-17-oic acid; (5β,8α,9β,10α,13α)-19-Hydroxykaur-15-en-17-oic acid. Grade: > 95%. CAS No. 115028-67-6. Molecular formula: C20H30O3. Mole weight: 318.5.
Pseudopalmatine
Pseudopalmatine isolated from the herbs of Tinospora sinensis. Uses: Antiplasmodial activity; anti-ache ic50 values. Synonyms: 5,6-Dihydro-2,3,10,11-tetramethoxydibenzo[a,g]quinolizinium; 5,6-Dihydro-8-desmethylcoralyne; 2,3,10,11-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium. Grade: > 95%. CAS No. 19716-66-6. Molecular formula: C21H22NO4. Mole weight: 352.4.
Psidial A
Psidial A, a natural triterpenoid isolated from the leaves of Psidium guajava L, exhibits the activity to enzyme PTP1B and also reduces tumor growth and stimulates uterus proliferation. Uses: Anti-tumour. Synonyms: (1S,4S,7R,11R,12R)-14,16-dihydroxy-1,5,5-trimethyl-8-methylidene-12-phenyl-19-oxatetracyclo[9.8.0.04,7.013,18]nonadeca-13,15,17-triene-15,17-dicarbaldehyde; 7,9-dihydroxy-2,2,4a- trimethyl-13-methylene-10-phenyl-1,2,2a,3,4,4a,10, 10a,11,12,13,13a-dodecahydrocyclobuta[6,7] cyclonona[b]chromene-6,8-dicarbaldehyde. Grade: >98%. CAS No. 1207181-35-8. Molecular formula: C30H34O5. Mole weight: 474.6.
Psoralen
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviolet radiation, can create covalent interstrand crosslinks, inducing apoptosis. Synonyms: Ficusin; Furocoumarin. Grade: 97 %. (HPLC). CAS No. 66-97-7. Molecular formula: C11H6O3. Mole weight: 186.16.
Psoralidin
Psoralidin is a furanocoumarin natural product used in Chinese medicine. Psoralidin, a PTP1B inhibitor, has been shown to have anticancer activity with a variety of mechanisms proposed. Psoralidin induces ROS generation in androgen-independent prostate cancer cells, leading to inhibition of cell proliferation. Psoralidin has been found to downregulate NOTCH1 signaling, causing growth arrest in both breast cancer stem cells and breast cancer cells. Uses: Anticancer and chemopreventive properties. Synonyms: 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one; 3,9-Dihydroxy-2-prenylcoumestan. Grade: >98%. CAS No. 18642-23-4. Molecular formula: C20H16O5. Mole weight: 336.34.
Pterisolic acid A
Pterisolic acid A is a natural diterpenoid found in the herbs of Pteris semipinnata. Synonyms: (4alpha,6alpha)-6,13-Dihydroxy-15-oxokaura-9(11),16-dien-18-oic acid. Grade: >98%. CAS No. 1401419-85-9. Molecular formula: C20H26O5. Mole weight: 346.4.
Pterisolic acid C
Pterisolic acid C is a natural diterpenoid found in the herbs of Pteris semipinnata. Synonyms: (4alpha)-13-Hydroxy-15-oxokaura-9(11),16-dien-18-oic acid. Grade: >98%. CAS No. 1401419-87-1. Molecular formula: C20H26O4. Mole weight: 330.4.
Pterisolic acid D
Pterisolic acid D is a natural diterpenoid found in the herbs of Pteris semipinnata. Synonyms: (4alpha,6beta)-6,9-Dihydroxy-15-oxokauran-18-oic acid. Grade: >97%. CAS No. 1401419-88-2. Molecular formula: C20H30O5. Mole weight: 350.5.
Pterisolic acid E
Pterisolic acid E is extracted from the herbs of Pteris semipinnata. Synonyms: (4alpha,12beta)-9,12-Dihydroxy-15-oxokauran-18-oic acid. Grade: 95.0%. CAS No. 1401419-89-3. Molecular formula: C20H30O5. Mole weight: 350.50.
Pterisolic acid F
Pterisolic acid F is a natural diterpenoid found in the herbs of Pteris semipinnata. Synonyms: (4alpha,16alpha)-9,16,17-Trihydroxy-15-oxokauran-18-oic acid. Grade: >95%. CAS No. 1401419-90-6. Molecular formula: C20H30O6. Mole weight: 366.5.
Pterokaurene L3
Pterokaurene L3 is a natural diterpenoid found in the herbs of Wedelia trilobata. Synonyms: 9beta-Hydroxy-ent-kaur-16-en-oic acid. Grade: >95%. CAS No. 77658-38-9. Molecular formula: C20H30O3. Mole weight: 318.46.
Pteroside D
Pteroside D is a natural sesquiterpenoid isolated from the herbs of Pteris multifida. Synonyms: (S)-6-[2-(β-D-Glucopyranosyloxy)ethyl]-2,3-dihydro-3-hydroxy-2,2,5,7-tetramethyl-1H-inden-1-one. Grade: >98%. CAS No. 35943-38-5. Molecular formula: C21H30O8. Mole weight: 410.5.
Pterostilbene
Pterostilbene is a natural plant anti-aging hormone. Pterostilbene has rich medicinal value and belongs to an antifungal active ingredient in blood products. Pterostilbene, a methylated derivative of resveratrol, has many biological activities such as whitening, anti-aging, anti-fungal, anti-oxidation, anti-tumor, hypolipidemia and antibacterial. Pterostilbene is a peroxisome proliferator-activated receptor alpha (PPAR-alpha) agonist. It is an antioxidant component of blueberries and Pterocarpus marsupium. Pterostilbene is a good functional cosmetics material. It is suitable for anti-aging, wrinkle removal, skin rejuvenation, sunscreen repair and relief, anti-inflammatory, antibacterial and analgesic, whitening, freckle removal, brightening, hair care, weight loss and other products, and it is compatible with lotion cream formula, gel formula and water formula. Synonyms: 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol; 4-Stilbenol, 3',5'-dimethoxy-, (E)-; Phenol, 4-[2-(3,5-dimethoxyphenyl)ethenyl]-, (E)-; (E)-2-(3,5-Dimethoxyphenyl)-1-(4-hydroxyphenyl)ethene; (E)-4-(3,5-Dimethoxystyryl)phenol; (E)-4-Hydroxy-3',5'-dimethoxystilbene; 3,5-Dimethoxy-4'-hydroxy-trans-stilbene; E-Pterostilbene; P 1499; Pterostilbene; trans-3,5-Dimethoxy-4'-hydroxystilbene; trans-Pterostilbene. Grade: >98%. CAS No. 537-42-8. Molecular formula: C16H16O3. Mole weight: 256.30.
Pteryxin
Pteryxin, a natural coumarin compound found in the herbs of Peucedanum harry-smithii var. subglabrum, shows muscle-relaxant property. Pteryxin exhibits hepatoprotective and nitric oxide production inhibitory activity. Uses: Muscle-relaxant. Synonyms: (Z)-2-Methyl-2-butenoic acid[(9R)-9-acetoxy-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10α-yl] ester. Grade: >98%. CAS No. 13161-75-6. Molecular formula: C21H22O7. Mole weight: 386.4.
[pThr3]-CDK5 Substrate
[pThr3]-CDK5 Substrate is an effective substrate of Phospho-Thr3CDK5. It is derived from the sequence of the histone H1 peptide that docks in the active site of CDK5. It is phosphorylated by CDK5 with a Km value of 6 μM. Synonyms: H-Pro-Lys-Thr(PO3H2)-Pro-Lys-Lys-Ala-Lys-Lys-Leu-OH; L-prolyl-L-lysyl-O3-phosphono-L-threonyl-L-prolyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-L-leucine; Pro-Lys-pTHR-Pro-Lys-Lys-Ala-Lys-Lys-Leu. Grade: ≥95%. CAS No. 1670273-47-8. Molecular formula: C53H100N15O15P. Mole weight: 1218.43.
It binds to insulin and acts as a substrate for insulin receptor tyrosine kinase. Synonyms: L-Lysine, L-threonyl-L-arginyl-L-α-aspartyl-L-isoleucyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-threonyl-L-α-aspartyl-O-phosphono-L-tyrosyl-O-phosphono-L-tyrosyl-L-arginyl-; Thr-Arg-Asp-Ile-pTyr-Glu-Thr-Asp-pTyr-pTyr-Arg-Lys. Grade: ≥95%. CAS No. 141171-54-2. Molecular formula: C72H110N19O33P3. Mole weight: 1862.67.
[pTyr5] EGFR 988-993
It is derived from the autophosphorylation site (Tyr992) of the epidermal growth factor receptor (EGFR 988-993) and is often complex with the catalytically inactive protein tyrosine phosphate 1B (PTP1B). Synonyms: H-Asp-Ala-Asp-Glu-Tyr(PO3H2)-Leu-OH; L-alpha-aspartyl-L-alanyl-L-alpha-aspartyl-L-alpha-glutamyl-O4-phosphono-L-tyrosyl-L-leucine; DADE-pTyr-L. Grade: ≥95%. CAS No. 159453-08-4. Molecular formula: C31H45N6O17P. Mole weight: 804.69.
Puerarin
Puerarin is a natural isoflavone extracted from Radix puerariae. Puerarin is the 8-C-glucoside of daidzein and a 5-HT2C receptor antagonist. Puerarin can be used in cosmetics material. Uses: Antioxidant. Synonyms: 8-b-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. Grade: >98%. CAS No. 3681-99-0. Molecular formula: C21H20O9. Mole weight: 416.38.
Pungiolide A
Pungiolide A is a sesquiterpene lactone isolated from the aerial parts of Xanthium sibiricum. Synonyms: Spiro[2H-cyclohepta[b]furan-3(3aH),6'(2'H)-furo[2',3':5,6]cyclohepta[1,2-b]pyran]-2,2'-dione, 7'-acetyl-3',3'a,4,4',4'a,7,8,8a,8'a,9',10',10'a-dodecahydro-8'a-hydroxy-7,9'-dimethyl-3'-methylene-6-[(1E)-3-oxo-1-butenyl]-, (3R,3aR,3'aR,4'aR,7R,8aS,8'aR,9'S,10'aR)-; Spiro[2H-cyclohepta[b]furan-3(3aH),6'(2'H)-furo[2',3':5,6]cyclohepta[1,2-b]pyran]-2,2'-dione, 7'-acetyl-3',3'a,4,4',4'a,7,8,8a,8'a,9',10',10'a-dodecahydro-8'a-hydroxy-7,9'-dimethyl-3'-methylene-6-(3-oxo-1-butenyl)-, [3'aR-[3'aα,4'aα,6'β[3aR*,6(E),7R*,8aS*],8'aβ,9'β,10'aα]]-; (3R,3aR,3a'R,4a'R,7R,8aS,8a'R,9'S,10a'R)-7'-acetyl-8a'-hydroxy-7,9'-dimethyl-3'-methylene-6-((E)-3-oxobut-1-en-1-yl)-3a,3',3a',4',4a',7,8,8a,8a',9',10',10a'-dodecahydro-2H,2'H,4H-spiro[cyclohepta[b]furan-3,6'-furo[2',3':5,6]cyclohepta[1,2-b]pyran]-2,2'-dione. Grade: ≥95%. CAS No. 130395-54-9. Molecular formula: C29H34O8. Mole weight: 510.58.
p-Vinylphenyl O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside is isolated from the herbs of Pteridium aquilinum. Synonyms: 4-Vinylphenyl 6-O-[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-glucopyranoside; p-Vinylphenyl 6-O-apio-β-D-furanosyl-β-D-glucopyranoside. Grade: 97.5%. CAS No. 112047-91-3. Molecular formula: C19H26O10. Mole weight: 414.40.
(Pyr3)-Amyloid β-Protein (3-40)
(Pyr3)-Amyloid β-Protein (3-40), a pyroglutamate-modified amyloid-β peptide extracted from Aβ40 and Aβ42, is a potential key player in the pathology of Alzheimer's disease (AD) due to its abundance in the brain, high aggregation propensity, stability and cytotoxicity. Synonyms: Pyr-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-pyroglutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valine. Grade: ≥95%. CAS No. 161818-04-8. Molecular formula: C187H283N51O53S. Mole weight: 4125.68.
Pyrocatechol monoglucoside is a natural phenol found in the herbs of Cajanus cajan. Synonyms: Pyrocatechol-O-beta-D-glucopyranoside; (2R,3S,4S,5R)-2-(HydroxyMethyl)-6-(2-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol. Grade: >98%. CAS No. 2400-71-7. Molecular formula: C12H16O7. Mole weight: 272.25.
Derived from the root of Cynanchum otophyllum Schneid, Qingyangshengenin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-oleandropyranosyl- (1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside stands as an intriguing natural compound with potential anti-tumor activity. This promising molecule is traditionally used in Chinese medicine and may be particularly effective in the treatment of hepatocellular carcinoma, a lethal form of cancer that is notoriously resistant to conventional therapies. Its active constituents exhibit a remarkably complex structure that is worthy of further study, as the implications for cancer treatment may be significant. Synonyms: AKOS040762539; 1808159-02-5; Qingyangshengenin 3-O-??-L-cymaropyranosyl-(1??4)-??-D-oleandropyranosyl-(1??4)-??-D-cymaropyranosyl-(1??4)-??-D-cymaropyranoside. Grade: 92.0%. CAS No. 1808159-02-5. Molecular formula: C56H84O20. Mole weight: 1077.27.
Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside is an intriguing natural compound derived from traditional Chinese medicine, notable for its exceptional antiviral and anti-inflammatory capabilities. Its efficacy in studying viral infections, inflammation-related disorders and sundry ailments has captivated the attention of scientific minds. Grade: 97.5%. CAS No. 1186628-87-4. Molecular formula: C41H58O14. Mole weight: 774.903.
Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside, a naturally occurring compound, is a promising medicinal agent that demonstrates profound therapeutic potential in treating cancer and cardiovascular diseases. Its potent anti-tumor activity and the ability to promote apoptosis in cancerous tissues make it an effective treatment for cancer. Furthermore, it possesses anti-inflammatory properties and can be employed as a therapeutic agent for heart failure by restoring cardiac function and reducing mortality rates. The multifaceted properties of this compound underscore its potential as a valuable asset for healthcare innovation. Grade: 98.0%. CAS No. 1186628-88-5. Molecular formula: C48H70O17. Mole weight: 919.074.
Quasar 570 CE Phosphoramidite
Quasar 570 dyes are cyanine derivatives of Cyanine 3. Cyanine dyes are a popular oligonucleotide modification and are commonly used for imaging, flow cytometry, and genomic applications. Grade: 95%. CAS No. 1032678-27-5. Molecular formula: C45H65F6N5O2P2. Mole weight: 883.99.
Quasar 670 CE Phosphoramidite
Quasar 670 dyes are cyanine derivatives of Cyanine 5. Cyanine dyes are a popular oligonucleotide modification and are commonly used for imaging, flow cytometry, and genomic applications. Synonyms: 3H-Indolium, 2-[5-[1-[6-[[trans-4-[[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]oxy]cyclohexyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl-, hexafluorophosphate(1-) (1:1). Grade: 95%. CAS No. 1032678-33-3. Molecular formula: C47H67F6N5O2P2. Mole weight: 910.02.
Quassin
Quassin is a natural diterpenoid found in the barks of Quassia amara L. It exhibits anti-larval activity at a concentration of 6 ppm. Uses: Anti-larval. Synonyms: Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy-. Grade: >96%. CAS No. 76-78-8. Molecular formula: C22H28O6. Mole weight: 388.5.
Quercetin 3-glucoside
Quercetin 3-glucoside, isolated from Lepisorus contortus, is used as an antineoplastic agent, a plant metabolite, a bone density conservation agent, an osteogenesis regulator, an antioxidant, a histamine antagonist, an antipruritic drug and a geroprotector. Synonyms: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-; 2-(3,4-Dihydroxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; Hirsutrin; 3-Glucosylquercetin; 3-O-β-D-Glucopyranosylquercetin; 3-β-D-Glucosylquercetin; 3',4',5,7-Tetrahydroxyflavone-3-β-D-glucopyranoside; Contigoside B; Glucosyl-3-quercetin; Isoquercetin; Isoquercetrin; Isoquercitrin; Isoquercitroside; NSC 115918; Quercetin 3-D-glucoside; Quercetin 3-mono-D-glucoside; Quercetin 3-monoglucoside; Quercetin 3-O-glucopyranoside; Quercetin 3-O-glucoside; Quercetin 3-O-β-D-glucopyranoside; Quercetin 3-O-β-D-glucoside; Quercetin 3-O-β-glucoside; Quercetin 3-β-D-glucopyranoside; Quercetin 3-β-D-glucoside; Quercetin 3β-glucoside; Quercetin 3β-O-glucoside; Quercetin glucoside; Quercetin-3-glucose; Quercetin-3-β-glucopyranoside; Quercetol 3-glucoside; Quercetol 3-monoglucoside; Sanmelin C 10; Sanmelin Powder C 10. Grade: 98%. CAS No. 482-35-9. Molecular formula: C21H20O12. Mole weight: 464.38.
Quercetin 3-O-glucuronide
Miquelianin, also known as Quercetin 3-O-glucuronide, a pharmacologically active flavonol glucuronide isolated from H. perforatum (St. John's wort), is a metabolite of quercetin. Synonyms: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl β-D-glucopyranosiduronic acid; Miquelianin; Mikwelianin; Q3GA; Quercetin 3-glucuronide; Quercetin 3-O-β-D-glucopyranosiduronic acid; Quercetin 3-O-β-D-glucuronide; Quercetin 3-O-β-D-glucuronopyranoside; Quercetin 3-β-D-glucuronide; Quercetin 3-β-D-glucuronopyranoside; Quercetin 3-β-glucuronide; Quercetin-3-O-β-glucuronide; Quercituron; Querciturone. Grade: 96.5%. CAS No. 22688-79-5. Molecular formula: C21H18O13. Mole weight: 478.36.
Quercetin 3-O-sophoroside
Quercetin-3-O-sophoroside is a flavonoid isolated from B. napus (rapeseed). It is the natural ligand of Bet v 1. Synonyms: QUOSP; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-5,7-dihydroxy-; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside. Grade: >98%. CAS No. 18609-17-1. Molecular formula: C27H30O17. Mole weight: 626.5.
Quinovic acid
Quinovic acid is a natural triterpenoid isolated from the herbs of Mitragyna rotundifolia. Quinovic acid glycosides purified fraction may prevent and/or treat cancers. Uses: Anti-cancer. Synonyms: (1S,2R,4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6b,9,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a,6a-dicarboxylic acid. Grade: >96%. CAS No. 465-74-7. Molecular formula: C30H46O5. Mole weight: 486.7.