BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| QS-21 | QS-21 is a natural triterpenoid saponin extracted from the soap bark tree. It has the potential use as an immunologic adjuvant in vaccine to enhance their efficacy. Synonyms: Saponin QA 21V1; QS-21. Grades: 90%. CAS No. 141256-04-4. Molecular formula: C92H148O46. Mole weight: 1990.13. |  |
| Qstatin | Qstatin is a potent and selective Vibrio QS inhibitor with an EC50 of 208.9 nM. Synonyms: 1-((5-Bromothiophen-2-Yl)Sulfonyl)-1H-Pyrazole; 1-(5-Bromothiophene-2-Sulfonyl)-1h-Pyrazole; MLS000044947; Q-Statin; Q Statin. Grades: 98%. CAS No. 902688-24-8. Molecular formula: C7H5BrN2O2S2. Mole weight: 293.2. | |
| Quarfloxin | Quarfloxin, also known as Quarfloxacin and CX-3543, is a fluoroquinolone derivative with antineoplastic activity. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells. Disruption of this G-quadruplex DNA:protein interaction in aberrant rRNA biogenesis may result in the inhibition of ribosome synthesis and tumor cell apoptosis. Synonyms: 3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)-1-pyrrolidinyl]-; 3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-(3-pyrazinyl-1-pyrrolidinyl)-; 5-Fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)-1-pyrrolidinyl]-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide; CX 3543; Itarnafloxin; Quarfloxacin. Grades: >98%. CAS No. 865311-47-3. Molecular formula: C35H33FN6O3. Mole weight: 604.69. | |
| Quaternium 73 | Quaternium-73 has excellent antistatic, bactericidal, antibacterial, antiseptic, emulsifying, dispersing, solubilizing, and corrosion-inhibiting properties. Quaternium 73 is an antibacterial agent used as a preservative in cosmetics. It can be applied to the treatment of acne and pimples. Synonyms: Pionin; Kankohso 201. Grades: 96%. CAS No. 15763-48-1. Molecular formula: C23H39IN2S2. Mole weight: 534.603. | |
| Quercetagetin | Quercetagetin is a flavonol that acts as an inhibitor of Pim-1 with IC50 value of 0.34 μM. It is derived from quercetin and exhibits antioxidant and antiviral effects. Uses: Enzyme inhibitors. Synonyms: 6-hydroxy Quercetin; NSC 115916; 3,3',4',5,6,7-Hexahydroxyflavone; 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxychromen-4-one. Grades: ≥98%. CAS No. 90-18-6. Molecular formula: C15H10O8. Mole weight: 318.2. | |
| Quercetagitrin | Quercetagitrin is a flavonoid isolated from Tagetes erecta L with anti-inflammatory activity. Synonyms: Quercetagetin-7-O-glucoside. Grades: 98%. CAS No. 548-75-4. Molecular formula: C21H20O13. Mole weight: 480.4. | |
| Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1-2)-L-rhamnoside | Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1-2)-L-rhamnoside is a flavonoid compound isolated from Ginkgo biloba L. Grades: > 98%. Molecular formula: C36H36O18. Mole weight: 756.66. | |
| Quercetin 3-Sambubioside | Quercetin 3-Sambubioside is a natural compound isolated from several plant such as Eucommia ulmoides, Corymbose Hedyotis Herb, lotus leaf. Synonyms: Quercetin 3-O-Sambubioside; Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside]. Grades: 98%. CAS No. 83048-35-5. Molecular formula: C26H28O16. Mole weight: 596.5. | |
| Quercetin Dihydrate | Quercetin Dihydrate is isolated from flower bud of Sophora flavescens Ait. Quercetin induces apoptosis, influences protein and lipid kinase signaling pathways. It reduces cancer risk of prostate, ovary, breast, gastric and colon cells. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 3,3',4',5,7-Pentahydroxyflavone; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one. Grades: >98%. CAS No. 6151-25-3. Molecular formula: C15H10O7. Mole weight: 302.24. | |
| Quercetin pentamethyl ether | Quercetin pentamethyl ether is found in the leaves of Talinum triangulare. Synonyms: Pentamethylquercetin; Penta-O-methylquercitin. Grades: > 95%. CAS No. 1247-97-8. Molecular formula: C20H20O7. Mole weight: 372.37. | |
| Quetiapine Impurity F (11-Chlorodibenzo[b,f][1,4]thiazepine) | An impurity of Quetiapine. Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Synonyms: 11-Chlorodibenzo[b,f][1,4]thiazepine; 11-chloro-dibenzo[b,f][1,4]thiazepine; 6-chlorobenzo[b][1,4]benzothiazepine; Dibenzo[b,f][1,4]thiazepine, 11-chloro-; GKL3VNL5B7; SCHEMBL8470; MLS004820230; DTXSID70442155; ZFOZNNFYECYUQB-UHFFFAOYSA-N; MFCD07782128; AKOS015901404; AC-5342; CS-W005837; 11-chlorodibenzo [b,f][1,4]thiazepine; 11-chlorodibenzo[b,f][1,4]-thiazepine; AS-63960; SMR003523800; 11 -chloro-dibenzo[b,f][1,4]thiazepine; (E)-11-chlorodibenzo[b,f][1,4]thiazepine; FT-0654690; C72504; EN300-103116; A807256; 10-chloro-2-thia-9-azatricyclo[9.4.0.0(3),?]pentadeca-1(11),3,5,7,9,12,14-heptaene; 10-chloro-2-thia-9-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,9,11,13-heptaene. Grades: > 95%. CAS No. 13745-86-3. Molecular formula: C13H8ClNS. Mole weight: 245.73. | |
| Quetiapine N-Oxide | A metabolite of Quetiapine. Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Synonyms: 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-Oxide; Quetiapine EP Impurity H. Grades: > 95%. CAS No. 1076199-40-0. Molecular formula: C21H25N3O3S. Mole weight: 399.52. | |
| Quin C1 | Quin C1, a quinazolinone derivative, is a potent and selective FPR2 agonist (EC50 = 40 nM). It was identified as a biased agonist, as it stimulated calcium mobilization through FPR2 but did not induce substantial neutrophil superoxide generation, even at concentrations up to 100 μM. Quin C1 induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Synonyms: 4-Butoxy-N-[1,4-dihydro-2-(4-methoxyphenyl)-4-oxo-3(2H)-quinazolinyl]benzamide. Grades: ≥98% by HPLC. CAS No. 786706-21-6. Molecular formula: C26H27N3O4. Mole weight: 445.51. | |
| Quinfamide | Quinfamide is an anti-amebic agent used to treat tropical parasitic infections. Synonyms: 2-Furancarboxylic Acid 1-(2,2-Dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl Ester; 1-(Dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydro-6-quinoline; Amenide; Amenox; Win 40014. Grades: > 95%. CAS No. 62265-68-3. Molecular formula: C16H13Cl2NO4. Mole weight: 354.19. | |
| quinidine gluconate | Quinidine gluconate is the gluconate salt form of quinidine, which has been used as an antiarrhythmic and antimalarial agent. Synonyms: Duraquin; Gluquinate; Dura-tab. Grades: 95%. CAS No. 7054-25-3. Molecular formula: C20H24N2O2.C6H12O7. Mole weight: 520.57. | |
| Quininib | Quininib is an antagonist of the cysteinyl leukotriene receptor 1 and 2 (CysLT1-2; IC50 = 1.4 μM and 38.5 μM, respectively). Quininib significantly inhibits angiogenic tubule formation in HMEC-1 cells, angiogenic sprouting in aortic ring explants and retinal revascularisation in OIR mice. Synonyms: 2-[(E)-2-(quinolin-2-yl)ethenyl]phenol; (E)-2-(2-(quinolin-2-yl)vinyl)phenol; AC1Q791J. Grades: 99%. CAS No. 143816-42-6. Molecular formula: C17H13NO. Mole weight: 247.29. | |
| Quizalofop-p-ethyl | Quizalofop-P-ethyl, a quinoxaline derivative, is a sort of post-emergence herbicide that might be effective in regulating annual and perennial grass weeds. Uses: Quizalofop-p-ethyl is a sort of post-emergence herbicide that might be effective in regulating annual and perennial grass weeds. Synonyms: 2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)-, ethylester, (r)-propanoicaci; assureii; ethyl(r)-2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)propanoate; nci-861094; QUIZALOFOP-P-ETHYL; QUINOFOP-P-ETHYL; DPX-Y6202-31; ETHYL (R)-2-[4-(6-CHLORO-2-QUINOXALYLOXY)PHENOXY]. Grades: 95%. CAS No. 100646-51-3. Molecular formula: C19H17ClN2O4. Mole weight: 372.80. | |
| QWF | QWF is a tripeptide substance P (SP) antagonist with IC50 value of 90 μM that inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Synonyms: Bgtcpo; N(alpha)-(N(alpha)-(N(alpha)-(tert-Butyloxycarbonyl)glutaminyl)-N(1)-formyl-tryptophyl)phenylalanine benzyl ester; Boc-gln-trp(cho)-phe-obzl. CAS No. 126088-82-2. Molecular formula: C38H43N5O8. Mole weight: 697.78. | |
| (R)-(+)-1,2-Epoxydecane | Synonyms: (+)-1,2-Epoxydecane; (R)-2-octyloxirane; Oxirane, 2-octyl-, (2R)-. Grades: 95%. CAS No. 67210-36-0. Molecular formula: C10H20O. Mole weight: 156.27. | |
| R-191 | R-191 is an IRAK-4 inhibitor that has the potential to treat hematological malignancy. Studies showed that it inhibited the production of cytokines induced by TLR and IL-1R in primary cells, as well as the expression of programmed death ligand-1 (PD-L1) in acute myeloid leukemia cell lines. Uses: The treatment of hematological malignancy. Synonyms: R-191; R 191; R191. | |
| (R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine hydrochloride | (R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine hydrochloride, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Synonyms: (αR)-α-Methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1-naphthalenemethanamine Hydrochloride; Cinacalcet Impurity 18. CAS No. 1229225-42-6. Molecular formula: C20H19ClF3N. Mole weight: 365.82. | |
| (R)-(+)-1-Phenyl-1-Cyclohexyl-mathanol | (R)-(+)-1-Phenyl-1-Cyclohexyl-mathanol (CAS# 3113-96-0 ) is a useful research chemical. Synonyms: (R)-Cyclohexylphenylmethanol. CAS No. 3113-96-0. Molecular formula: C13H18O. Mole weight: 190.28. | |
| (R)-3-Hydroxybutyric acid | (R)-3-Hydroxybutyric acid, characterized by its role in energy metabolism, serves as a biomarker for metabolic disorders such as diabetes. In addition, it exhibits therapeutic potential in the management of neurodegenerative diseases like Alzheimer's and Parkinson's, highlighting its significance in biomedical research and clinical applications. Synonyms: (R)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutanoate. Grades: 95%. CAS No. 625-72-9. Molecular formula: C4H8O3. Mole weight: 104.1. | |
| (R)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol | An intermediate used in the synthesis of Duloxetine, an antidepressant. CAS No. 116539-57-2. Molecular formula: C8H13NOS. Mole weight: 171.26. | |
| R406 | R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling (EC(50) for degranulation=56-64 nM). The primary target for R406 is the spleen tyrosine kinase (Syk). R406 inhibited phosphorylation of Syk substrate linker for activation of T cells in mast cells and B-cell linker protein/SLP65 in B cells. R406 bound to the ATP binding pocket of Syk and inhibited its kinase activity as an ATP-competitive inhibitor (K(I)=30 nM). Furthermore, R406 blocked Syk-dependent FcR-mediated activation of monocytes/macrophages and neutrophils and BCR-mediated activation of B lymphocytes. R406 is orally bioavailable, achieving exposures capable of inhibiting Syk-dependent IgE-mediated basophil activation. Collectively, the results show R406 potential for modulating Syk activity in human disease. Synonyms: R 406; R-406. CAS No. 841290-80-0. Molecular formula: C22H23FN6O5. Mole weight: 470.45. | |
| R406 Benzenesulfonate | R406 is a potent Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Synonyms: R406; R 406; R-406. Grades: >98%. CAS No. 841290-81-1. Molecular formula: C28H29FN6O8S. Mole weight: 628.63. | |
| R 428 dihydrochloride | R 428 dihydrochloride is a potent and selective inhibitor of Axl receptor tyrosine kinases (IC50 = 14 nM). R428 inhibits Axl kinase and Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Synonyms: R 428 dihydrochloride; R428 dihydrochloride; R-428 dihydrochloride; 1-(6,7-dihydro-5H-benzo[2,3]cyclohepta[2,4-d]pyridazin-3-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine dihydrochloride; Thiocolchicoside dihydrochloride. Grades: 99%. CAS No. 2108833-51-6. Molecular formula: C30H34N8.2HCl. Mole weight: 579.57. | |
| (R)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide | An impurity of Brinzolamide, a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE 1,1-DIOXIDE; (4R)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide; SCHEMBL3576264; (R)-4-HYDROXY-2-(3-METHOXYPROPYL)-3,4-DIHYDRO-2H-THIENO[3,2-E][1,2]THIAZINE-6-SULFONAMIDE1,1-DIOXIDE. CAS No. 165117-54-4. Molecular formula: C10H16N2O6S3. Mole weight: 356.44. | |
| (R)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid | (R)-5-(3-(Heptyloxy)-5-(octan-2-yloxy)benzyloxy)isophthalic acid, a highly promising drug candidate, has been extensively analyzed due to its remarkable anti-inflammatory, anti-cancer and neuroprotective properties. In addition, its outstanding potency in counteracting diabetes and metabolic disorders has been revealed. Despite initial success, further exploration is warranted to completely grasp and harness its therapeutic potential. This entails in-depth investigation of its complex mechanisms of action, side-effect profile, and pharmacokinetics, among other factors, to consider its potential as a clinical agent. Synonyms: 5-({3-(Heptyloxy)-5-[(2R)-2-octanyloxy]benzyl}oxy)isophthalic acid; 1,3-Benzenedicarboxylic acid, 5-[[3-(heptyloxy)-5-[[(1R)-1-methylheptyl]oxy]phenyl]methoxy]-. Grades: ≥95%. Molecular formula: C30H42O7. Mole weight: 514.65. | |
| R 59-022 | R 59-022 is a diacylglycerol (DAG) kinase inhibitor (IC50 = 2.8 μM) without affecting phosphodiesterase or phosphatidylinositol kinase, and potentiates the activity of protein kinase C by inhibiting diacylglycerol metabolism. R 59-022 also blocks vascular contraction induced by the thromboxane analog U-46619. At 10 μM, R 59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. Uses: Enzyme inhibitors. Synonyms: R59022; R-59022; R 59022; 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; Diacylglycerol Kinase Inhibitor I. Grades: ≥98% by HPLC. CAS No. 93076-89-2. Molecular formula: C27H26FN3OS. Mole weight: 459.58. | |
| R-59-949 | R-59-949 is an inhibitor of diacylglycerol kinase α (DGK-α) expressed in vascular smooth muscle cells. It inhibits inducible nitric oxide production in vascular smooth muscle cells through decreasing transplasmalemmal L-arginine uptake. Synonyms: Diacylglycerol Kinase Inhibitor II; DKGI-II; R 59949; R 59 949. Grades: ≥98%. CAS No. 120166-69-0. Molecular formula: C28H25F2N3OS. Mole weight: 489.6. | |
| R 7050 | R 7050 is an inhibitor of TNF-α receptor 1 signaling. Synonyms: R-7050; R 7050; R7050; TNF-α Antagonist III; 8-chloro-4-phenylsulfanyl-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline; 12E-954; SMR000169297; AC1LSEB1; Bionet1_000448; MLS000543328; CHEMBL1440293; SCHEMBL12058463; CTK8G3499. CAS No. 303997-35-5. Molecular formula: C16H8ClF3N4S. Mole weight: 380.77. | |
| R788 disodium hexahydrate | R788 sodium salt hydrate, a methylene phosphate prodrug of the active metabolite R406, is a potent Syk inhibitor. It can be rapidly converted to R406 in vivo. It effectively inhibits BCR signaling in vivo, resulting in reduced proliferation and survival of the malignant B cells and significantly prolonged survival of the treated animals. Synonyms: Fostamatinib disodium hexahydrate; R788 disodium hexahydrate; R 788 disodium hexahydrate; R-788 disodium hexahydrate. Grades: >98%. CAS No. 914295-16-2. Molecular formula: C23H24FN6Na2O9P. Mole weight: 624.42. | |
| R-8507 | R-8507 is an antagonist of the TNF-α type 1 receptor (TNF-αRI). It inhibits the expression of intercellular adhesion molecule-1 (ICAM-1) induced by TNF-α and IL-1β in an ELISA using A549 lung epithelial cells. Synonyms: 1-(4-chlorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline. Grades: ≥98%. CAS No. 338773-13-0. Molecular formula: C16H8ClF3N4. Mole weight: 348.7. | |
| Rabeprazole EP Impurity C | An impurity of Rabeprazole. A degradation product formed in stressed tablets of Rabeprazole sodium. Synonyms: 1-(1H-Benzimidazol-2-yl)-1,4-dihydro-3-methyl-4-oxo-2-pyridinecarboxylic Acid. Grades: 95%. CAS No. 1163685-30-0. Molecular formula: C14H11N3O3. Mole weight: 269.25. | |
| Rabeprazole N-Oxide | An impurity of Rabeprazole. Rabeprazole is proton pump inhibitor as an antiulcer drug. Synonyms: 2-[[[4-(3-Methoxypropoxy)-3-methyl-1-oxido-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; 2-[[[1-Oxide-4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; Rabeprazole EP Impurity D. Grades: > 95%. CAS No. 924663-38-7. Molecular formula: C18H21N3O4S. Mole weight: 375.45. | |
| Rabeximod | Rabeximod is an immunomodulator agent. It can suppress arthritis by preventing activation of inflammatory cells, most likely macrophages, in a time dependent fashion, downstream of TLR2 and TLR4 stimulation. Phase II development for Rheumatoid arthritis is ongoing. Uses: Rheumatoid arthritis. Synonyms: 2-(9-chloro-2,3-dimethyl-6H-indolo[2,3-b]quinoxalin-6-yl)-N-[2-(dimethylamino)ethyl]acetamide; ROB-803; ROB-803; ROB-803; Rabeximod. Grades: 98%. CAS No. 872178-65-9. Molecular formula: C22H24ClN5O. Mole weight: 409.92. | |
| rac (8-Hydroxyquinolin-3-yl)alanine Dihydrochloride | Rac (8-Hydroxyquinolin-3-yl)alanine Dihydrochloride is used in the genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe. Synonyms: 2-Amino-3-(8-hydroxyquinolin-3-yl)propanoic Acid Dihydrochloride. CAS No. 1123191-88-7. Molecular formula: C12H14Cl2N2O3. Mole weight: 305.155. | |
| rac-Benidipine HCl | Cas No. 91599-74-5. | |
| rac-CCT 250863 | rac-CCT 250863 is a potent Nek2 inhibitor (IC50 = 73 nM). Synonyms: rac-CCT 250863; rac-CCT250863; rac-CCT-250863; 4-[2-Amino-5-[4-[(dimethylamino)methyl]-2-thienyl]-3-pyridinyl]-2-[[(2Z)-4,4,4-trifluoro-1-methyl-2-buten-1-yl]oxy]benzamide. Grades: ≥98% by HPLC. CAS No. 1364269-06-6. Molecular formula: C24H25F3N4O2S. Mole weight: 490.54. | |
| rac-cis-Ambroxol | Cas No. 107814-37-9. | |
| (R)-Acenocoumarol | Acenocoumarol is a short-lived oral anticoagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. Synonyms: (R)-Acenocoumarin; (R)-Nicoumalone; 4-hydroxy-3-[(1R)-1-(4-nitrophenyl)-3-oxobutyl]chromen-2-one. Grades: ≥98%. CAS No. 66556-77-2. Molecular formula: C19H15NO6. Mole weight: 353.3. | |
| rac-Lavandulol | Rac-Lavandulol is a fragrance of lavender oil. Synonyms: (+/-)-Lavandulol; 5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-ol; 4-Hexen-1-ol, 5-methyl-2-(1-methylethenyl)-; 2-Isopropenyl-5-methylhex-4-en-1-ol. CAS No. 58461-27-1. Molecular formula: C10H18O. Mole weight: 154.253. | |
| rac-N-Desmethyl Bedaquiline | rac-N-Desmethyl Bedaquiline is an intermediate used in th synthesis of Bedaquiline, a medication approved for the treatment of active tuberculosis. Synonyms: N-Monodesmethyl bedaquiline. CAS No. 654654-76-9. Molecular formula: C31H29BrN2O2. Mole weight: 541.5. | |
| Rac-Sitagliptin | Rac-Sitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Uses: Dipeptidyl-peptidase iv inhibitors. Synonyms: Sitagliptin Raccemate; Sitagliptin impurity E; 7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; 4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine. Grades: >95%. CAS No. 823817-56-7. Molecular formula: C16H15F6N5O. Mole weight: 407.31. | |
| Rac-Vildagliptin Impurity F | An impurity of Vildagliptin. Vildagliptin is a new dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: Vildagliptin Related Compound 3; Vildagliptin Lactam; (S)-2-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. CAS No. 1789703-36-1. Molecular formula: C17H24N2O3. Mole weight: 304.39. | |
| RADA 16 | RADA 16 is a self-complementary peptide that has been widely studied for various applications in biocompatible materials. Grades: 95%. CAS No. 289042-25-7. Molecular formula: C66H113N29O25. Mole weight: 1712.8. | |
| Raddeanoside 20 | Raddeanoside 20 is a triterpenoid compound isolated from the rhizomes of Anemone raddeana Regel. Synonyms: (4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-6a-(hydroxymethyl)-10-[(2S,3R,4S,5S)-4-hydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,2,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Grades: >98%. CAS No. 335354-79-5. Molecular formula: C47H76O17. Mole weight: 913.108. | |
| Ralinepag | This active molecular is a Epoprostenol receptor agonist which is an investigational drug candidate developed by Arena and intended for the treatment of vasospastic diseases, for an example, Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin which elicits a potent vasodilation and inhibits platelet aggregation when binding to this receptor. In Jan 2015, Phase-II clinical trials in Pulmonary arterial hypertension in USA was on going. In Jul 2015, Phase-II clinical trials in Pulmonary arterial hypertension in Spain was on going. In Jul 2015, Arena initiated enrolment in a phase II extension trial for Pulmonary arterial hypertension in USA, Czech Republic, Hungary, Poland. Uses: Pulmonary arterial hypertension. Synonyms: 2- [ [4- [ [ (4-chlorophenyl) -phenylcarbamoyl] oxymethyl] cyclohexyl] methoxy] acetic acid,APD-811; APD 811; APD811; Ralinepag. Grades: 98%. CAS No. 1187856-49-0. Molecular formula: C23H26ClNO5. Mole weight: 431.91. | |
| Raloxifene hydrochloride | Raloxifene is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used for prevention of osteoporosis in postmenopausal women. Uses: Prevention of osteoporosis in postmenopausal women. Synonyms: PD 0332991 isethionate; PD0332991 isethionate; PD-0332991 isethionate; Evista; Raloxifene Hcl; Keoxifene hydrochloride; (6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone hydrochloride. Grades: >98%. CAS No. 82640-04-8. Molecular formula: C28H28ClNO4S. Mole weight: 510.04. | |
| RAMB4 | RAMB4 is a ubiquitin-proteasome system (UPS)-stressor. RAMB4 inhibits ubiquitin-mediated protein degradation upstream of the 20S proteasomal catalytic activites. Synonyms: PTP1B-IN-9; 3,5-bis(3,4-dichlorobenzylidene)piperidin-4-one. CAS No. 145888-79-5. Molecular formula: C19H13Cl4NO. Mole weight: 413.13. | |
| Ramelteon | Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: (S)-N-[2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl]propionamide; TAK-375. Grades: >98%. CAS No. 196597-26-9. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| Ramelteon Impurity 7 HCl | Ramelteon Impurity 7 HCl is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: 2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine hydrochloride; Ramelteon Stage-2 Impurity HCl. Grades: >98%. CAS No. 1053239-39-6. Molecular formula: C13H17NO.HCl. Mole weight: 239.74. | |
| Ramelteon Impurity D | Ramelteon Impurity D is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-(2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)isobutyramide. CAS No. 880152-61-4. Molecular formula: C17H23NO2. Mole weight: 273.37. | |
| Ramelteon Impurity E | Ramelteon Impurity E is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-[2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acetamide. CAS No. 196597-16-7. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| Ramelteon Impurity F | Ramelteon Impurity F is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Synonyms: N-(2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionamide. CAS No. 196597-17-8. Molecular formula: C16H21NO2. Mole weight: 259.34. | |
| Ramifenazone | Ramifenazone is a non-steroidal anti-inflammatory synthetic reagent. Uses: Anti-inflammatory. Synonyms: 1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one; 4-isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; 4-isopropylaminoantipyrine; isopropylaminophenazone. Grades: ≥98%. CAS No. 3615-24-5. Molecular formula: C14H19N3O. Mole weight: 245.32. | |
| Ramipril | Ramipril is a second generation angiotensin-converting enzyme (ACE) inhibitor that acts as a prodrug, which is hydrolyzed in vivo to the active metabolite ramiprilat. It is used in treatment of congestive heart failure, hypertension and heart attacks. It is also useful in preventing renal and retinal complications in diabetes. It was developed by Pfizer and has been listed. Uses: Ramipril is used in treatment of congestive heart failure, hypertension and heart attacks. it is also useful in preventing renal and retinal complications in diabetes. Synonyms: (2s-(1(r*(r*)), 2-alpha, 3a-beta, 6a-beta))-henylpropyl)amino)-1-oxopropyl;cyclopenta(b)pyrrole-2-carboxylicacid, octahydro-1-(2-((1-(ethoxycarbonyl)-3-p;Tritace;Altace;Carasel;Ramace;(2S, 3aS, 6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3, 3a, 4, 5, 6, 6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid. Grades: >99%. CAS No. 87333-19-5. Molecular formula: C23H32N2O5. Mole weight: 416.51. | |
| Ramipril related compound A | An impurity of Ramipril, an angiotensin-converting enzyme inhibitor used to treat hypertension and congestive heart failure. Synonyms: Ramipril Methyl Ester. Grades: 95%. CAS No. 108313-11-7. Molecular formula: C22H30N2O5. Mole weight: 402.5. | |
| R-Amlodipine | R-Amlodipine is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: (R)-Amlodipine; (R)-(+)-Amlodipine; Amlodipine; (4R)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester. Grades: >98%. CAS No. 103129-81-3. Molecular formula: C20H25ClN2O5. Mole weight: 408.87. | |
| Ranitidine Related Compound A | An impurity of Ramipril, an ACE inhibitor that can be used to treat hypertension. Synonyms: 2-(((5-((Dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine fumarate. CAS No. 91224-69-0. Molecular formula: C14H22N2O5S. Mole weight: 330.40. | |
| Rankinidine | Rankinidine is found in Gelsmium elegans. Synonyms: Humantenine, 4-demethyl-. Grades: > 95%. CAS No. 106466-66-4. Molecular formula: C20H24N2O3. Mole weight: 340.42. | |
| Rapamycin (Sirolimus) | Cas No. 53123-88-9. | |
| Rapanone | Rapanone is found in Embelia laeta. Synonyms: 2,5-Dihydroxy-3-tridecyl-2,5-cyclohexadiene-1,4-dione. Grades: > 95%. CAS No. 573-40-0. Molecular formula: C19H30O4. Mole weight: 322.44. | |
| Rapastinel | Rapastinel, a brain penetrable tetrapeptide, could be a partial agonist of NMDA receptor. It was already finished the Phase II trial for acting as an antidepressant agent. It was just planed a phase III trial for Major depressive disorder. Uses: Rapastinel is a brain penetrable tetrapeptide and could be a partial agonist of nmda receptor. Synonyms: GLYX-13; GLYX 13; GLYX13; BV-102; BV102; BV 102; TPPT-amide; Rapastinel; UNII-6A1X56B95E; GLYX-13 trifluoroacetate; TPPT-amide trifluoroacetate. Grades: ≥98% by HPLC. CAS No. 117928-94-6. Molecular formula: C18H31N5O6. Mole weight: 413.47. | |
| Raphin 1 | Raphin 1 is an orally bioavailable and BBB-penetrant inhibitor of the regulatory subunit PPP1R15B of protein phosphatase, displays >30-fold selectivity for PPP1R15B over PPP1R15A. Raphin 1 inhibits PPP1R15B-mediated dephosphorylation and protein synthesis in vitro. It was shown to be effective in a mouse model of Huntington's disease. Synonyms: (2E) -2-[ (2, 3-Dichlorophenyl) methylene]hydrazinecarboximidamide. Grades: ≥98% by HPLC. CAS No. 2022961-17-5. Molecular formula: C8H8Cl2N4. Mole weight: 231.08. | |
| R-(-)-Arundic Acid | R-(-)-Arundic Acid, also called as ONO 2506, is an astrocyte modulating agent which can treat neurodegenerative diseases including Alzheimer's disease and Parkinson's disease. Uses: An astrocyte modulating agent, in acute ischemic stroke. Synonyms: (2R)-2-propyloctanoic acid; (R)-(-)-2-propyloctanoic acid; arundic acid; ONO-2506; ONO2506; ONO 2506; MK-0724; MK 0724; MK0724. Grades: 95%. CAS No. 185517-21-9. Molecular formula: C11H22O2. Mole weight: 186.29. | |
| Ras Inhibitory Peptide | Ras inhibitory peptide is a synthetic peptide inhibitor that blocks the interaction of the GEF with Grb2, suppressing Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor. Synonyms: ?Sos SH3 Domain Inhibitor?. Grades: ≥95%. CAS No. 159088-48-9. Molecular formula: C53H91N19O11. Mole weight: 1170.4. | |
| (R)-Baclofen | (R)-Baclofen is the R-enantiomer of Baclofen, which is a specific GABA-B receptor agonist and muscle relaxant (skeletal). It is primarily used to treat spasticity. Synonyms: (βR)-β-(Aminomethyl)-4-chlorobenzenepropanoic Acid; (-)-Baclofen; (R)-(-)-Baclofen; (R)-4-Amino-3-(4-chlorophenyl)butanoic Acid; (R)-4-Amino-3-(4-chlorophenyl)butyric Acid; D-Baclofen; R-(-)-Baclofen; l-Baclofen; AGI 006; Arbaclofen; NSC 334693; NSC334693; NSC-334693; STX209; STX-209; STX 209; (R)-Baclofen; D-Baclofen; Arbaclofen. Grades: 98%. CAS No. 69308-37-8. Molecular formula: C10H12ClNO2. Mole weight: 213.66. | |
| Rbin-1 | Rbin-1 (ribozinoindole-1) is a potent and reversible inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family (GI50 value 136 nM in wild-type cells). Rbin-2 can be used as a chemical probe for the eukaryotic ribosome assembly. Uses: Chemical probe for the eukaryotic ribosome assembly. Synonyms: Rbin-1; Rbin 1; Rbin1; Ribozinoindole-1; 3-[(2-methylprop-2-en-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole; 3-[(2-methyl-2-propenyl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole. Grades: 99%. CAS No. 328023-11-6. Molecular formula: C13H12N4S. Mole weight: 256.33. | |
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