BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Pixantrone | Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Uses: Topoisomerase ii inhibitors. Synonyms: Pixuvri; BBR-2778; BBR2778; BBR 2778. Grades: >98%. CAS No. 144510-96-3. Molecular formula: C17H19N5O2. Mole weight: 325.37. |  |
| Pizotifen malate | Pizotifen is a benzocycloheptene-based drug used for the treatment of recurrent migraine headaches. It acts as an antagonist of 5-HT2A and 5HT2C receptors. Synonyms: BC-105; BC 105; BC105. Grades: >98%. CAS No. 5189-11-7. Molecular formula: C19H21NS·C4H6O5. Mole weight: 429.53. | |
| PJ34 | PJ34 is a novel and potential PARP inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP-1 (IC(50) = 20 nM). Synonyms: PJ34; PJ-34; PJ 34. CAS No. 344458-15-7. Molecular formula: C17H18ClN3O2. Mole weight: 331.8. | |
| PK14105 | PK14105, a isoquinoline derivative, could bind to peripheral-type benzodiazepine sites so that it might be a potential radioligand to locate areas of neuronal damage. Uses: Pk14105, a isoquinoline derivative, could bind to peripheral-type benzodiazepine sites so that it might be a potential radioligand to locate areas of neuronal damage. Synonyms: 107257-28-3; PK-14105; PK 14105; PK14105; 3-Isoquinolinecarboxamide,1-(2-fluoro-5-nitrophenyl)-N-methyl-N-(1-methylpropyl)-; N-BUTAN-2-YL-1-(2-FLUORO-5-NITRO-PHENYL)-N-METHYL-ISOQUINOLINE-3-CARBOXAMIDE; ACMC-20maxf. Grades: 95%. CAS No. 107257-28-3. Molecular formula: C21H20FN3O3. Mole weight: 381.40. | |
| PKC-Theta Inhibitor | PKC-theta inhibitor is a selective PKC-theta inhibitor with IC50 of 12 nM. Synonyms: CHEMBL248183; N4-((4-(Aminomethyl)Cyclohexyl)Methyl)-5-Nitro-N2-(2-(Trifluoromethoxy)Benzyl)Pyrimidine-2,4-Diamine; VC-8650; SCHEMBL3953579. Grades: 98%. CAS No. 736048-65-0. Molecular formula: C20H25F3N6O3. Mole weight: 454.4. | |
| PKM2-IN-1 | PKM2-IN-1 is a PKM2 inhibitor with IC50 value of 2.95 μM. Synonyms: PKM2 inhibitor; Compound 3k; (3-methyl-1,4-dioxonaphthalen-2-yl)methyl piperidine-1-carbodithioate. CAS No. 94164-88-2. Molecular formula: C18H19NO2S2. Mole weight: 345.48. | |
| PKR-IN-2 | PKR-IN-2 is a pyruvate kinase (PKR) activator. IC50: PKR (R510Q) <100 nM. Synonyms: N-[4-[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]phenyl]quinoxaline-5-sulfonamide PKR-IN-2 SCHEMBL16049613. CAS No. 1628428-01-2. Molecular formula: C24H28N4O4S. Mole weight: 468.57. | |
| PKSI-527 | PKSI-527 is a potent and selective inhibitor of plasma kallikrein with Ki value of 0.81 μM. PKSI-527 may be a useful tool for exploring the mechanism of disseminated intravascular coagulation (DIC) and the accompanying organ failure. Synonyms: 2-[4-[[ (2S) -2-[[4- (aminomethyl) cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]acetic acid hydrochloride. Grades: ≥95%. CAS No. 128837-71-8. Molecular formula: C25H31N3O4·HCl. Mole weight: 474. | |
| PKUMDL WQ 2101 | PKUMDL WQ 2101 is a negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 34.8 μM). It exhibits antitumor activity in vitro in breast cancer cell lines overexpressing PHGDH (EC50 values are 7.7 and 10.8 μM in MDA-MB-468 and HCC-70 cells, respectively). Synonyms: 2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide. Grades: ≥98% by HPLC. CAS No. 304481-72-9. Molecular formula: C14H11N3O6. Mole weight: 317.25. | |
| PKUMDL WQ 2201 | PKUMDL WQ 2201 is a negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 35.7 μM). It exhibits antitumor activity. Synonyms: 2-Chloro-4-[5-[[2-[ (ethylamino) thioxomethyl]hydrazinylidene]methyl]-2-furanyl]benzoic acid. Grades: ≥98% by HPLC. CAS No. 592474-91-4. Molecular formula: C15H14ClN3O3S. Mole weight: 351.81. | |
| Plantainoside D | Plantainoside D is a natural compound of the sesquiterpenoid class. Synonyms: 2-(3,4-Dihydroxyphenyl)ethyl 3-O-beta-D-glucopyranosyl-beta-D-glucopyranoside 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]; Isoplantamajoside. Grades: >98%. CAS No. 147331-98-4. Molecular formula: C29H36O16. Mole weight: 640.59. | |
| Platycodin D3 | Platycodin D3 has anti-hepatitis C virus (HCV) activity. It can be used as an expectorant in a variety of lung inflammatory diseases and regulate the production and secretion of mucin in the airway. Platycodin D3 is a triterpenoid compound and an inhibitor of NF-κB. Synonyms: Olean-12-en-28-oic acid, 3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23,24-tetrahydroxy-, O-D-apio-β-D-furanosyl-(1?3)-O-β-D-xylopyranosyl-(1?4)-O-6-deoxy-α-L-mannopyranosyl-(1?2)-α-L-arabinopyranosyl ester, (2β,3β,16α)-; 3-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-{[6-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy}-2,16,23,24-tetrahydroxy-28-oxoolean-12-en-28-yl]-α-L-arabinopyranose. Grades: >98%. CAS No. 67884-03-1. Molecular formula: C63H102O33. Mole weight: 1387.46. | |
| Platycoside E | Platycoside E is a triterpenoid compound. Synonyms: Platycoside E; 237068-41-6; CHEBI:70449; HY-N3522; AKOS040735041; MS-32197; CS-0023701; Q27138787. Grades: >98%. CAS No. 237068-41-6. Molecular formula: C69H112O38. Mole weight: 1549.62. | |
| Platycoside G1 | Platycoside G1 is a triterpenoid compound found in the roots of Platycodon grandiflorum. Synonyms: Deapi-platycoside E. Grades: >98%. CAS No. 849758-42-5. Molecular formula: C64H104O34. Mole weight: 1417.502. | |
| Plerixafor | Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. Uses: Anti-hiv agents. Synonyms: Plerixafor; SDZ SID 791; Mozobil; JKL 169; JM 3100; JKL169; JM3100; JKL-169; JM-3100. Grades: >98%. CAS No. 110078-46-1. Molecular formula: C28H54N8. Mole weight: 502.78. | |
| Plicatol B | Plicatol B is a phenanthrene isolated from the stems of the orchid Flickingeria fimbriata. Synonyms: Moscatin; 4-methoxyphenanthrene-2,5-diol. Grades: >98%. CAS No. 108335-06-4. Molecular formula: C15H12O3. Mole weight: 240.258. | |
| Plumbagin | Plumbagin, a natural 1,4-naphthoquinone first isolated from plants of the genus Plumbago, induces apoptosis in cancer cells. Plumbagin exhibited effective cell growth inhibition via inducing cancer cells to undergo G2/M phase arrest and apoptosis. Synonyms: 5-Hydroxy-2-methyl-1,4-naphthalenedione; 2-Methyljuglone; 5-Hydroxy-2-methyl-1,4-naphthoquinone; NSC 236613; NSC 688284; Plumbagine; Plumbagone. Grades: ≥98% by HPLC. CAS No. 481-42-5. Molecular formula: C11H8O3. Mole weight: 188.18. | |
| Pluripotin | SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo. Uses: Self-renewal. Synonyms: SC-1; SC 1; SC1; Pluripotin. Grades: 0.98. CAS No. 839707-37-8. Molecular formula: C27H25F3N8O2. Mole weight: 550.54. | |
| PLX 647 dihydrochloride | PLX 647 is a potent dual KIT/Fms inhibitor (IC50= 16 and 28 nM respectively). PLX 647 blocks activation of macrophages, osteoclasts and mast cells in both cell based and in vivo inflammation models. Synonyms: PLX 647 dihydrochloride; PLX647 dihydrochloride; PLX-647 dihydrochloride; 5-(1H-Pyrrolo[2,3-b]pyridin-3-ylmethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine dihydrochloride. Grades: ≥97% by HPLC. CAS No. 1779796-38-1. Molecular formula: C21H17F3N4.2HCl. Mole weight: 455.3. | |
| PLX-7683 | PLX-7683, a pyrrolopyridine derivative, has been found to be a paradox breaker that was studied to exhibit more durable efficacy and better safety than some former RAF inhibitors. Synonyms: PLX7683; PLX-7683; PLX 7683; Sulfamide, N'-[4-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-3,5-difluorophenyl]-N-ethyl-N-methyl-. Grades: 98%. CAS No. 1652573-86-8. Molecular formula: C23H19ClF2N4O3S. Mole weight: 504.94. | |
| PMA | PMA, extracted from seeds of Euphorbia lathyris L, is a phorbol ester that is commonly used to activate certain types of protein kinase C (PKC), including group A (α, βI, βII, γ) and group B (δ, ε, η, θ) isoforms. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. Synonyms: Phorbol-12-Myristate-13-Acetate; 12-O-Tetradecanoylphorbol 13-acetate, 4β, 9α, 12β, 13α, 20-Pentahydroxytiglia-1, 6-dien-3-one 12-tetradecanoate; 12 Myristoyl 13 acetylphorbol; 12 O Tetradecanoyl Phorbol 13 Acetate; 12-Myristoyl-13-acetylphorbol; 12-O-Tetradecanoyl Phorbol 13-Acetate; 13-Acetate, 12-O-Tetradecanoyl Phorbol; Acetate, Phorbol Myristate; Acetate, Tetradecanoylphorbol; Myristate Acetate, Phorbol; Phorbol 13-Acetate, 12-O-Tetradecanoyl; Phorbol Myristate Acetate; Tetradecanoylphorbol Acetate; Tetradecanoylphorbol Acetate, 4a alpha Isomer; Tetradecanoylphorbol Acetate, 4a alpha-Isomer. Grades: ≥95%. CAS No. 16561-29-8. Molecular formula: C36H56O8. Mole weight: 616.83. | |
| PMX 464 | PMX 464, a thiol-reactive quinol and putative thioredoxin inhibitor, is a putative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system, which shown to inhibit Trx and induce a G1/S block in HT29 cells, and inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Synonyms: PMX464; PMX-464; PMX 464; 4-(2-Benzothiazolyl)-4-hydroxy-2,5-cyclohexadien-1-one. Grades: ≥98% by HPLC. CAS No. 485842-97-5. Molecular formula: C13H9NO2S. Mole weight: 243.28. | |
| PNC-27 | PNC-27 is an anti-cancer peptide that induces tumor cell necrosis of a poorly differentiated non-solid tissue human leukemia cell line depending on expression of HDM-2 in the plasma membrane of these cells. Grades: 98%. | |
| Pneumocandin B0 | Pneumocandin B0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Uses: Antifungal. Synonyms: L-688,786; L 688,786; L688,786; L-688786; L 688786; L688786; (3S)-(4R,5R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]- 4,5-dihydroxy-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-3-hydroxy-L-proline (6?1)-Lactam. Grades: >98%. CAS No. 135575-42-7. Molecular formula: C50H80N8O17. Mole weight: 1065.21. | |
| p-[N-(p-Fluorophenyl)formimidoyl]phenol | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: 4-(4-HYDROXYBENZYLIDENE) FLUORO ANILINE; 4-(((4-FLUOROPHENYL)IMINO)METHYL)PHENOL; 2-(4 ' -Hydrophenyl)-4-fluorobenyl imine; alpha-4-Fluorophenylimino-p-cresol; (E)-4-((4-Fluorophenylimino)methyl)phenol; 4-fluoro-N-(hydroxyphenyl)methylene-benzenamine; E2:4{[(4. Grades: 98%. CAS No. 3382-63-6. Molecular formula: C13H10FNO. Mole weight: 215.22. | |
| Pocapavir | Pocapavir has been found to be an antienterovirus agent that could probably be effctive against enterovirus infections. The Phase-II trial for Poliomyelitis has not been reported yet since 2012. Synonyms: SCH-48973; SCH48973; SCH 48973; V074; V 073; V-073; 1, 3-Dichloro-2- ({4-[ (2-chloro-4-methoxyphenoxy) methyl]benzyl}oxy) benzene; 1[2-chloro-4-methoxy-phenyl-oxymethyl]-4-[2,6-dichloro-phenyl-oxymethyl]-benzene; Benzene,1-[(2-chloro-4-methoxyphenoxy)methyl]-4-[(2,6-dichlorophenoxy)methyl]. Grades: 98%. CAS No. 146949-21-5. Molecular formula: C21H17Cl3O3. Mole weight: 423.71. | |
| Polaprezinc | Polaprezinc is a chelate composed of zinc and L-carnosine, which exhibits gastroprotective, antioxidant, anti-ulcer and anti-inflammatory effects. It is approved in Japan for the treatment of gastric ulcers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Zinc, [β-alanyl-κN-L-histidinato(2-)-κN,κO]-; L-Histidine, N-β-alanyl-, zinc complex; Zinc, [N-β-alanyl-L-histidinato(2-)-N,NN,Oα]-; Promac; Promac (antiulcer agent); Z 103; Zinc L-carnosine; β-Alanyl-L-histidinato zinc. Grades: 95%. CAS No. 107667-60-7. Molecular formula: C9H12N4O3Zn. Mole weight: 289.61. | |
| Policosanol | Policosanol is a mixture of long-chain alcohols found in plant waxes. Policosanol supplement is used as a lipid-lowering agent and potential hypotensive agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Grades: 90%. CAS No. 142583-61-7. Molecular formula: CH3(CH2)nCH2OH. | |
| Polidocanol | Cas No. 3055-99-0. | |
| Polmacoxib | Polmacoxib is a first-in-class NSAID drug candidate that acts as a dual inhibitor of COX-2 and carbonic anhydrase (CA). It exhibits superior safety for cardiovascular, renal, and gastrointestinal tissues due to its dual COX-2 and CA binding properties. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Synonyms: CG100649; CG-100649; CG 100649; polmacoxib; 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide. Grades: > 98%. CAS No. 301692-76-2. Molecular formula: C18H16FNO4S. Mole weight: 361.387. | |
| Polyadenosinic acid potassium salt | Commonly used for DNA/RNA extraction. Synonyms: Poly A potassium salt; Poly Ra Potassium Salt; Poly-Adenylic Acid potassium salt; Polyadenylic Acid 5' Potassium Salt; Poly A-K. Grades: ≥85%. CAS No. 26763-19-9. Molecular formula: (C10H11O6N5PK)n. Mole weight: (367.30)n. | |
| Polycarbomethylsilane | Polycarbomethylsilane, an organosilicon polymer that has excellent biocompatibility, holds promise as a drug delivery agent because of its ability to both encapsulate and safeguard fragile drugs. It is an enticing avenue of inquiry for encapsulating and releasing drugs, especially in cancer therapy and other illnesses. Synonyms: PCMS; Poly[(methylsilylene)methylene]; Polycarbosilane. CAS No. 62306-27-8. Molecular formula: (C2H6Si)n. | |
| Polyethylene glycol 15-hydroxystearate | Polyethylene glycol 15-hydroxystearate is a nonionic surfactant and emulsifier. Synonyms: Macrogol (15)-Hydroxystearate; Kolliphor HS15; Solutol HS15. CAS No. 70142-34-6. Molecular formula: C18H36O3(C2H4O)n. | |
| Polygalacic acid | Polygalacic Acid is a compound of the triterpenoid saponins that can promote the cholinergic system reactivity. Synonyms: (4aR, 5R, 6aR, 6aS, 6bR, 9R, 10R, 11S, 12aR, 14bR)-5, 10, 11-trihydroxy-9-(hydroxymethyl)-2, 2, 6a, 6b, 9, 12a-hexamethyl-1, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b-tetradecahydropicene-4a-carboxylic acid. Grades: >98%. CAS No. 22338-71-2. Molecular formula: C30H48O6. Mole weight: 504.708. | |
| Polygalasaponin XXXI | Polygalasaponin XXXI is a triterpenoid compound found in the herbs of Polygala japonica Houtt. In vivo, Polygalasaponin XXXI exhibits inhibitory effect on proliferation of mouse adapted influenza virus A/PR/8/34 and cyclic AMP phosphodiesterase. Synonyms: Polygalasaponin XXXI|79103-90-5|Polygalasaponin XXXI;Onjisaponin F|AKOS037514965. Grades: >98%. CAS No. 79103-90-5. Molecular formula: C75H112O36. Mole weight: 1589.685. | |
| Poly-L-arginine hydrochloride | Poly-L-arginine hydrochloride has been used: as polyelectrolyte solution in the synthesis of biodegradable capsules as layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shells in assay for the determination of binding activity of C-reactive protein for polycationic ligands. Synonyms: Poly(L-arginine hydrochloride); L-Arginine, homopolymer, hydrochloride. Grades: 95%. CAS No. 26982-20-7. Molecular formula: C18H39ClN12O4. Mole weight: 523. | |
| Polymyxin B nonapeptide | Polymyxin B nonapeptide interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: Polymyxin B Cyclononapeptide; Polymyxin B1, 1-De(N2-(6-Methyl-1-Oxooctyl)-L-2,4-Diaminobutanoic Acid)-; PMBN; T-Dab-Dab-Dab-Dab-d-FL-Dab-Dab-T (Lactam: Dab3-Thr9); N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); Nα-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-). Grades: ≥95%. CAS No. 86408-36-8. Molecular formula: C43H74N14O11. Mole weight: 963.13. | |
| Poly(N,N-(1,3-phenylene)isophthalamide) | Poly(N,N-(1,3-phenylene)isophthalamide) can be used in heat and flame protective clothing. Synonyms: 1,3-Benzenediamine-1,3-benzenedicarbonyl dichloride copolymer; 1,3-Benzenediamine-isophthalyl chloride copolymer; m-Diaminobenzene-isophthaloyl chloride copolymer; m-Phenylenediamine-isophthaloyl chloride copolymer. CAS No. 25765-47-3. Molecular formula: C14H12Cl2N2O2. Mole weight: 311.2. | |
| Polyporusterone A | Polyporusterone A is a steroid isolated from Polyporus umbellatus (zhu ling). CAS No. 141360-88-5. Molecular formula: C28H46O6. Mole weight: 478.67. | |
| Poly(trimethylsilyl)propyne | Synonyms: Poly-1-Trimethylsilyl-2-Methylacetylene; Poly(1-trimethylsilyl-1-propyne); Silane, trimethyl-1-propyn-1-yl-, homopolymer; Silane, trimethyl-1-propynyl-, homopolymer; 1-Methyl-2-trimethylsilylacetylene homopolymer; 1-Trimethylsilyl-1-propyne homopolymer; 1-Trimethylsilyl-1-propyne polymer; Methyl(trimethylsilyl)acetylene, homopolymer; Poly(1-trimethylsilyl-2-methyl)acetylene; Poly(1-trimethylsilylpropyne); Poly(trimethyl-1-propynylsilane); Poly(trimethylsilylpropyne); Poly[methyl (trimethylsilyl)acetylene]; PolyTMSP; PTMSP; SSP 070; SSP 070-10GM; Trimethyl-1-Propynylsilane homopolymer; Trimethylsilyl-1-propyne homopolymer. Grades: ≥95%. CAS No. 87842-32-8. Molecular formula: (C6H12Si)x. | |
| Polyvinylimidazole | Polyvinylimidazole (CAS# 25232-42-2 ) is a useful research chemical. Synonyms: 1-Vinylimidazole; 1-Vinyl-1H-imidazole; N-Vinylimidazole; 1H-Imidazole, 1-ethenyl-; Lufixan. CAS No. 25232-42-2. Molecular formula: (C5H6N2)n. Mole weight: 94.11. | |
| Pomalidomide | Promotes degradation of transcription factors SALL4, IKZF1 and IKZF3. Synonyms: CC4047; CC 4047; CC-4047; Pomalidomide. Brand name: Pomalyst. Grades: ≥99% (HPLC). CAS No. 19171-19-8. Molecular formula: C13H11N3O4. Mole weight: 273.24. | |
| Pomalidomide-C2-NH2 | Pomalidomide-C2-NH2 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. Synonyms: 4-((2-aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; SCHEMBL17884390; TQP0427; Cereblon Ligand-Linker Conjugates 15; HY-128846; Pomalidomide-C2-NH2; Pomalidomide-alkylC2-amine; E3 ligase Ligand 17; 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride. Grades: > 98%. CAS No. 1957235-66-3. Molecular formula: C15H16N4O4. Mole weight: 316.31. | |
| Pomalidomide-PEG3-C2-NH2 hydrochloride | Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate containing a cereblon ligand based on Pomalidomide and a PEG linker of 3 O(CH2)2 units with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Synonyms: Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride. CAS No. 2446474-09-3. Molecular formula: C21H29ClN4O7. Mole weight: 484.93. | |
| Pomalidomide-PEG5-CO2H | Pomalidomide-PEG5-CO2H is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal carboxylic acid for reactivity with an amine on the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid. Grades: ≥98%. CAS No. 2139348-63-1. Molecular formula: C26H35N3O11. Mole weight: 565.57. | |
| Ponesimod | Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented t...tal drug for the treatment of multiple sclerosis (ms) and psoriasis. Synonyms: ACT-128800; ACT 128800; ACT128800; Ponesimod. (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl)thiazolidin-4-one;4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]Methylene]-3-(2-Methylphenyl)-2-(propyliMino)-, (2Z,5Z)-;ACT-128800;5-[3-Chloro-4-[((2R)-2,3-dihydroxypropyl)oxy]benz-(Z)-ylidene]-2-((Z)-propylimino)-3-(o-tolyl)thiazolidin-4-one;(5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-one. Grades: ≥ 95.0%. CAS No. 854107-55-4. Molecular formula: C23H25ClN2O4S. Mole weight: 460.97. | |
| POPC | POPC is phosphatidylcholine, a diacylglycerol and phospholipid. Its full name is 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. BOC Sciences provides high-quality POPC for your projects. Uses: Giant popc liposomes have been used to study the effect of non-ionic detergent on liposomes. Synonyms: 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC; 1,2-POPC; POPC (16:0/18:1 PC). Grades: ≥ 98%. CAS No. 26853-31-6. Molecular formula: C42H82NO8P. Mole weight: 760.08. | |
| Posaconazole | Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: For research used only. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; Noxafil; Sch 56592. Grades: >98%. CAS No. 171228-49-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer 1 (R,R,R,R) | Posaconazole Diastereoisomer 1 (R,R,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Impurity 31; all-(R)-Posaconazole; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one; (3R,5R,2R,3R)-posaconazole. Grades: 95%. CAS No. 170985-61-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Diastereoisomer Related Compound 1 | Posaconazole Diastereoisomer Related Compound 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (5R-trans)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester; 1,4-Anhydro-2,3,5-trideoxy-4-C-(2,4-difluorophenyl)-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-5-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol. Grades: > 95%. CAS No. 159811-30-0. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer Related Compound 2 | Posaconazole Diastereoisomer Related Compound 2 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol; D-erythro-Pentitol, 2, ?5-anhydro-1, ?3, ?4-trideoxy-2-C- (2, ?4-difluorophenyl) ?-4-[[[ (4-methylphenyl) ?sulfonyl]?oxy]?methyl]?-1- (1H-1, ?2, ?4-triazol-1-yl) ?-. Grades: > 95%. CAS No. 166583-12-6. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer Related Compound 5 | Posaconazole Diastereoisomer Related Compound 5 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-L-threo-pentitol. Grades: > 95%. CAS No. 149809-42-7. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. | |
| Posaconazole Diastereoisomer (S,R,S,S) | Posaconazole Diastereoisomer (S,R,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3S,5R,2S,3S)-Posaconazole. Grades: 95%. CAS No. 213381-02-3. Molecular formula: C37H42F2N8O4. Mole weight: 700.78. | |
| Posaconazole Impurity 33 Oxalate | Posaconazole Impurity 33 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide oxalate; 2-[ (1S, 2S) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde Oxalate. Grades: >95%. CAS No. 1887197-42-3. Molecular formula: C13H20N2O2.C2H2O4. Mole weight: 326.34. | |
| Potassium (4-methoxy) benzyloxymethyltrifluoroborate | Alkoxymethyltrifluoroborate undergoes palladium-catalyzed carbon-carbon bond formation (Suzuki-Miyuara reaction) with aryl chlorides to provide a non-traditional disconnection for the preparation of aryl- and heteroaryl ethers. Synonyms: Potassium trifluoro(((4-methoxybenzyl)oxy)methyl)borate. Grades: 95 %. CAS No. 1027642-26-7. Molecular formula: C9H11BF3KO2. Mole weight: 258.087. | |
| Pozanicline | Pozanicline, a pyridine derivative, has been found to be a nicotinic receptor modulator that was once studied in Alzheimer's disease as a neuroprotective agent. Synonyms: Pozanicline; ABT-089; ABT 089; ABT089; A-87089; A-87089.0; Pozanicline; UNII-CL2002R563; CHEMBL127071; Pozanicline (USAN); 2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine. Grades: 98%. CAS No. 161417-03-4. Molecular formula: C11H16N2O. Mole weight: 192.26. | |
| PPACKII trifluoroacetate salt | PPACKII is a specific and irreversible inhibitor of glandular and plasma kallikreins. Human tissue kallikreins (hKs) are a class of secreted serine proteases that is involved in the release of vasodepressor peptides or kinins from a plasma substrate. Synonyms: H-D-Phe-Phe-Arg-Chloromethyl Ketone; (2R)-2-amino-N-[(2S)-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide trifluoroacetate salt. Grades: ≥95%. CAS No. 649748-23-2. Molecular formula: C25H33ClN6O3·2CF3COOH. Mole weight: 729.1. | |
| PPACK trifluoroacetate salt | PPACK is a non-competitive inhibitor of human alpha-thrombin. It was shown to inhibit thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). Synonyms: Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone. Grades: ≥95%. Molecular formula: C21H31ClN6O3·xCF3COOH. Mole weight: 450.96. | |
| PPIase-Parvulin Inhibitor | PPIase-Parvulin Inhibitor is a cell-permeable inhibitor of the PPIases Pin1 and Pin4 (IC50s = 1.5 and 1.0 μM, respectively). It blocks the proliferation of cancer cells that overexpress Pin1 and Pin4 (IC50 = 2-5 μM). Synonyms: HIC 016C; PiB; Diethyl-1, 3, 6, 8-tetrahydro-1, 3, 6, 8-tetraoxobenzo[lmn][3, 8]phenanthroline-2, 7-diacetate. Grades: ≥95%. CAS No. 64005-90-9. Molecular formula: C22H18N2O8. Mole weight: 438.4. | |
| PPNDS | PPNDS is a potent and selective P2X1 receptor antagonist (pKB = 7.43 in rat vas deferens). PNDS is approximately 50-fold less selective for P2Y1R and does not interact with α1A-adrenergic, adenosine A1 and A2B, histamine H1, or muscarinic M3 receptors. Synonyms: Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt. CAS No. 1021868-77-8. Molecular formula: C18H11N4Na4O14PS2. Mole weight: 694.36. | |
| Pracinostat | Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors. Synonyms: SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat. Grades: >98%. CAS No. 929016-96-6. Molecular formula: C20H30N4O2. Mole weight: 358.486. | |
| Praliciguat | Praliciguat is a soluble guanylate cyclase stimulator, which can enhance NO signal transduction and act as a vasodilator. Synonyms: IW-1973. Grades: ≥98% by HPLC. CAS No. 1628730-49-3. Molecular formula: C21H14F8N6O2. Mole weight: 534.4. | |
| Pramipexole Impurity E | An impurity of Pramipexole which is a thiazole derivative usually used as a D2-receptor agonist. Synonyms: N-(2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)propionamide; (S)-Pramipexole Amide Pramipexole related compound B; Pramipexole EP lmpurity E; Pramipexole USP Related Compound E. Grades: >95%. CAS No. 106006-84-2. Molecular formula: C10H15N3OS. Mole weight: 225.31. | |
| Pramiracetam | Pramiracetam is a central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. It is a more potent nootropic drug derived from piracetam. Synonyms: CP-945598 HCl; CP945598 HCl; CP 945598 HCl. Grades: >98%. CAS No. 68497-62-1. Molecular formula: C14H27N3O2. Mole weight: 269.38. | |
| Pramlintide acetate hydrate | Pramlintide is an analog of amylin, an antidiabetic peptide hormone released into the bloodstream. It has been used in the treatment of diabetes. Grades: 98%. CAS No. 196078-30-5. Molecular formula: C173H273N51O56S2. Mole weight: 4027.46. | |
| Prasugrel Acetyl Impurity | An impurity of Prasugrel.Prasugrel is a platelet inhibitor. It can be used to prevent formation of blood clots. Synonyms: 5-(1-(2-Fluorophenyl)-2-oxopropyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)acetate. Grades: > 95%. CAS No. 1443034-67-0. Molecular formula: C18H18FNO3S. Mole weight: 347.41. | |
| Prasugrel Hydroxy Thiolactone | Cas No. 947502-66-1. | |
| Prasugrel Impurity I | Cas No. 1391194-45-8. | |
| Prasugrel Impurity II | Cas No. 1391194-39-0. | |
| Prasugrel Impurity III | Cas No. 1391194-50-5. | |
Our database is helping our users find suppliers everyday.
