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Oxocrebanine
Oxocrebanine is an anti-breast cancer active aporphine alkaloid found in S. hainanensis. Oxocrebanine is a Topo I/IIα dual inhibitor, catalytic inhibitor and DNA intercalator. Synonyms: 9,10-dimethoxy-8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-8-one; 8H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-one, 9,10-dimethoxy-. Grades: > 95%. CAS No. 38826-42-5. Molecular formula: C19H13NO5. Mole weight: 335.31.
Oxonic acid potassium salt
Oxonic acid potassium salt is an inhibitor of uricase. It has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism. Synonyms: potassium;4,6-dioxo-1H-1,3,5-triazine-2-carboxylate. Grades: > 98 %. CAS No. 2207-75-2. Molecular formula: C4H2KN3O4. Mole weight: 195.17.
Oxtriphylline
Oxtriphylline is a cough medicine derived from xanthine used in the treatment for chronic asthma. Uses: A cough medicine derived from xanthine. Synonyms: 2-Hydroxy-N,N,N-trimethyl-ethanaminium salt with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dioneion(1-), 2-hydroxy-N,N,N-trimethylethanaminium. Grades: ≥98%. CAS No. 4499-40-5. Molecular formula: C12H21N5O3. Mole weight: 283.33.
oxypeucedanin
Oxypeucedanin, a derivative of coumarin of natural origins, has exhibited encouraging outcomes in the management of diverse medical conditions. Its potential as a cure for inflammatory diseases like arthritis is attributed to its anti-inflammatory characteristics. Moreover, oxypeucedanin has demonstrated anticancer features, particularly in the care for breast cancer. Its capacity for inducing apoptosis and hindering tumor growth elevates it as a propitious therapeutic alternative. Synonyms: Oxypeucedarin; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)-; 4-[(3,3-dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one; 5-[(3,3-dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g]chromen-7-one. Grades: >98%. CAS No. 737-52-0. Molecular formula: C16H14O5. Mole weight: 286.28.
Oxypeucedaninhydrate
Oxypeucedanin hydrate usually can be found in the roots of Angelica dahurica. It exhibited carbohydrate metabolizing enzymes inhibitory effect. Uses: Antimutagenic / antioxidant / antimicrobial. Synonyms: (+)-4-[(R)-2,3-Dihydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one; Hydroxypeucedanin hydrate; Prangol; Prangolarin hydrate; Aviprin. Grades: >98%. CAS No. 2643-85-8. Molecular formula: C16H16O6. Mole weight: 304.29.
Oxyphencyclimine hydrochloride
Oxyphencyclimine hydrochloride is a muscarinic cholinergic receptor antagonist for the treatment of peptic ulcers and the relief of smooth muscle spasms in the gastrointestinal. Synonyms: Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, hydrochloride (1:1); Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester, monohydrochloride; Cyclohexaneglycolic acid, α-phenyl-, (1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)methyl ester monohydrochloride; (1-Methyl-1,4,5,6-tetrahydro-2-pyrimidyl)methyl α-cyclohexyl-α-phenylglycolate hydrochloride; (1-Methyl-1,4,5,6-tetrahydropyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride; (±)-Oxyphencyclimine hydrochloride; Daricol; Daricon; Dominil; Enterex; NSC 528449; Oximin; S 1-1236; Setrol; Syklifen; Ulcociclinina; Vio-Thene. Grades: ≥99%. CAS No. 125-52-0. Molecular formula: C20H28N2O3.HCl. Mole weight: 344.45.
Ozagrel
Ozagrel is an antiplatelet agent working as a thromboxane A2 (TXA2) synthesis inhibitor. It has been a clinical objective for many years. lt is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXA2 with an IC50 of 11 nM. lt was selected as the best compound of highly selective inhibitors of TXA2 synthase. lt increased 6-keto-PGF1 alpha in various isolated cells and tissues. It blunted and delayed the decrease in cardiac output and maintained end-systolic pressure-diameter relation, +dp/dt, and lung lymph flow at baseline values. Uses: Ozagrel was selected as the best compound of highly selective inhibitors of txa2 synthase. lt increased 6-keto-pgf1 alpha in various isolated cells and tissues. Synonyms: OKY046; OKY 046; OKY-046; 2-Propenoic acid,3-[4-(1H-imidazol-1- ylmethyl)phenyl]-,(2E)-;(E)-p-(Imidazol-1-ylmethyl)cinnamic acid;(E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid;(E)-3-[P-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid. Grades: >98%. CAS No. 82571-53-7. Molecular formula: C13H12N2O2. Mole weight: 228.25.
Ozagrel hydrochloride
Ozagrel hydrochloride is a thromboxane synthetase inhibitor with IC50 value of 4 nM. Uses: Enzyme inhibitors. Synonyms: (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 74003-18-2. Molecular formula: C13H12N2O2.HCl. Mole weight: 264.71.
Ozagrel sodium
Ozagrel is a thromboxane A2 synthase inhibitor used as an antiplatelet agent. It reduces the risk of neurological impairment and the volume of brain damage. Synonyms: KCT-0809; Cataclot; Xanbo; (E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoate sodium. CAS No. 189224-26-8. Molecular formula: C13H11N2O2·Na. Mole weight: 250.23.
Ozenoxacin
Ozenoxacin is a novel topical antibacterial agent in the class of quinolone. Its 1% topical cream is approved for the treatment of impetigo in Canada and US. Synonyms: 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxoquinoline-3-carboxylic acid. CAS No. 245765-41-7. Molecular formula: C21H21N3O3. Mole weight: 363.4.
P053
P053 is an inhibitor of ceramide synthase 1 (CerS1). Synonyms: (2S)-2-amino-4-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-2-methylbutan-1-ol. Grades: ≥95%. CAS No. 2748196-63-4. Molecular formula: C18H21Cl2NO2. Mole weight: 354.27.
P1
A protein disulfide isomerase inhibitor with IC50 value of 1.7 μM. It can inhibit the proliferation of numerous cancer cell lines. Synonyms: PDI-IN-P1; PDI IN P1; PDIINP1; PDI inhibitor P1; PDI-inhibitor-P1; N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide. Grades: ≥98% by HPLC. CAS No. 1461648-55-4. Molecular formula: C30H37N3O7S. Mole weight: 583.7.
P21d hydrochloride
P21d hydrochloride is a breast tumor kinase inhibitor with IC50 value of 30 nM. It can restore E-cadherin expression and suppress migration in breast cancer cells. Synonyms: [4-[[6-Cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino]-3-fluorophenyl]-4-morpholinylmethanone hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C23H22FN7O2.HCl. Mole weight: 483.93.
P22077
P22077 is a potent and selective ubiquitin-specific protease 7 (USP7) inhibitor. P22077 potently induces apoptosis in NB cells with an intact USP7-HDM2-p53 axis but not in NB cells with mutant p53 or without human homolog of MDM2 (HDM2) expression. P22077 was found to be able to sensitize chemoresistant LA-N-6 NB cells to chemotherapy. In an in vivo orthotopic NB mouse model, P22077 significantly inhibited the xenograft growth of three NB cell lines. USP7-specific inhibitors like P22077 may serve not only as a stand-alone therapy but also as an effective adjunct to current chemotherapeutic regimens for treating NB with an intact USP7-HDM2-p53 axis. Synonyms: P-22077; P 22077. Grades: 0.98. CAS No. 1247819-59-5. Molecular formula: C12H7F2NO3S2. Mole weight: 315.309.
p53 and MDM2 proteins-interaction-inhibitor chiral
p53 and MDM2 proteins-interaction-inhibitor chiral is an inhibitor of the interaction between p53 and MDM2 proteins. Synonyms: 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)Ethanone;Ethanone, 2-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)-, rel-;p53 and MDM2 proteins-interaction-inhibitor. Grades: 95%. CAS No. 939981-37-0. Molecular formula: C40H49Cl2N5O4. Mole weight: 734.76.
p53 and MDM2 proteins-interaction-inhibitor racemic
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins. Synonyms: rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone;Ethanone, 2-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-diMethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-diMethyl-1H-iMidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-Morpholinyl)-;2-[4-[(4R,5S)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazole-1-carbonyl]piperazin-1-yl]-1-morpholin-4-ylethanone. Grades: 95%. CAS No. 939983-14-9. Molecular formula: C40H49Cl2N5O4. Mole weight: 734.76.
P7C3
P7C3 is a proneurogenic and neuroprotective agent that activates NAMPT. P7C3 protects neurons from apoptosis and promotes neurogenesis in mice. It also improves cognitive function and memory in aged mice. Synonyms: 1-Anilino-3-(3,6-dibromocarbazol-9-yl)propan-2-ol; 1-(3,6-Dibromo-carbazol-9-yl)-3-phenylamino-propan-2-ol; 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol; 1-(3,6-dibromocarbazol-9-yl)-3-(phenylamino)propan-2-ol. Grades: >98%. CAS No. 301353-96-8. Molecular formula: C21H18Br2N2O. Mole weight: 474.196.
P7C3-OMe
P7C3-OMe, also known as (R)-P7C3-OMe, is a methoxy derivative of parent compound P7C3, an aminopropyl carbazole that exhibits antidepressant and neuroprotective activities. P7C3 inhibits MPTP-induced neuronal death in animal models of Parkinson's disease and delays the onset and preserves motor function in animal models of amyotrophic lateral sclerosis (ALS). Synonyms: (2R)-1-(3,6-dibromocarbazol-9-yl)-3-(3-methoxyanilino)propan-2-ol; P7C3-OMe; (R)-P7C3-OMe. CAS No. 1235481-43-2. Molecular formula: C22H20Br2N2O2. Mole weight: 504.22.
PACAP 6-27
Cas No. 136134-68-4.
PACMA 31
PACMA 31 is a protein disulfide isomerase family inhibitor as promising target for chemotherapy. It inhibits growth of ovarian cancer cells. Synonyms: PACMA 31; PACMA31; PACMA-31; N-(2,4-Dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycylglycine ethyl ester. Grades: ≥99% by HPLC. CAS No. 1401089-31-3. Molecular formula: C21H22N2O6S. Mole weight: 430.47.
Pacritinib
Pacritinib is an orally bioavailable and ATP-competitive inhibitor of JAK2 (IC50 = 23 nM), and also inhibits FLT3 (IC50 = 22 nM). It suppresses proliferation in cells carrying the JAK2V617F mutation. Uses: For research used only. Synonyms: SB1518; SB-1518. Grades: >98%. CAS No. 937272-79-2. Molecular formula: C28H32N4O3. Mole weight: 472.589.
PAFAH1b2/3-IN-P11
P11 is an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH) 1b2 and 1b3. At 10 μM, it has been shown to impair Neuro2a and PC3 tumor cell survival. Synonyms: (2S,6S)-6-(4-Tert-butylphenyl)-2-(4-methylphenyl)-1-(4-methylphenyl)sulfonyl-3,6-dihydro-2H-pyridine-5-carboxylic acid. Grades: ≥98%. CAS No. 942285-55-4. Molecular formula: C30H33NO4S. Mole weight: 503.7.
PALDA
PALDA is an endogenous lipid and it can potentiate effects of endovanilloids at TRPV1 receptors. Synonyms: N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide. Grades: ≥98% by HPLC. CAS No. 136181-87-8. Molecular formula: C24H41NO3. Mole weight: 391.59.
Palifosfamide
Palifosfamide is a synthetic mustard compound with potential antineoplastic activity. An active metabolite of ifosfamide covalently linked to the amino acid lysine for stability, palifosfamide irreversibly alkylates and cross-links DNA through GC base pairs, resulting in irreparable 7-atom inter-strand cross-links; inhibition of DNA replication and cell death follow. Unlike ifosfamide, this agent is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. In addition, because palifosfamide does not require activation by aldehyde dehydrogenase, it may overcome the tumor resistance seen with ifosfamide. Synonyms: Isophosphamide mustard; Isophosphoramide mustard; IPAM; bis(2-chloroethylamino)phosphinic acid. Grades: ≥ 98%. CAS No. 31645-39-3. Molecular formula: C4H11Cl2N2O2P. Mole weight: 221.018.
Palifosfamide tromethamine
Palifosfamide tromethamine is a synthetic mustard compound with potential antineoplastic activity. It is an active metabolite of ifosfamide covalently linked to the amino acid lysine for stability. It inhibits DNA replication and cell death. It is not metabolized to acrolein or chloroacetaldehyde, metabolites associated with bladder and CNS toxicities. It may overcome the tumor resistance seen with ifosfamide. It was developed by Dekk-Tec and in clinic phase 3 with no progress. Uses: Palifosfamide tromethamine has potential antineoplastic activity. Synonyms: 2-Amino-2-(hydroxymethyl)propane-1,3-diol;Bis(2-chloroethylamino)phosphinic acid;ZIO201;ZIO-201;NSC297900;NSC-297900;N,N'-Bis(2-chloroethyl)phosphorodiamidic acid. Grades: >98%. CAS No. 1070409-31-2. Molecular formula: C8H22Cl2N3O5P. Mole weight: 342.15.
Paliperidone
An atypical antipsychotic for the treatment of mental disorders such as schizophrenia and schizoaffective disorder. Synonyms: 9-Hydroxyrisperidone; Invega; Paliperidona; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; Invega; Paliperidone; R 76477; RO 76477. Grades: ≥98%. CAS No. 144598-75-4. Molecular formula: C23H27FN4O3. Mole weight: 426.48.
Paliperidone Impurity 4
An impurity of Paliperidone which is an active metabolite of RISPERIDONE and used as a second generation (atypical) antipsychotic agent. Synonyms: Paliperidone 2-Hydroxybenzoyl Impurity; 3-[2-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one ;Paliperidone Impurity 4. Grades: > 95%. CAS No. 152542-03-5. Molecular formula: C23H28FN3O4. Mole weight: 429.5.
Paliperidone Palmitate
An impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Synonyms: 9-Hydroxyrisperidone Palmitate; Invega Sustenna; RO 92670; Hexadecanoic Acid 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Ester. Grades: > 95%. CAS No. 199739-10-1. Molecular formula: C39H57FN4O4. Mole weight: 664.91.
Paliperidone Palmitate N-Oxide
A metabolite of Paliperidone Palmitate, an impurity of Paliperidone which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Synonyms: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Hexadecanoate; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl Ester Hexadecanoic Acid. CAS No. 1404053-60-6. Molecular formula: C39H57FN4O5. Mole weight: 680.89.
A useful research chemical. Synonyms: 4-(2-propenyl)-pheno; 4-(Prop-2-enyl)-phenol; Chavicol; gamma-(p-Hydroxyphenyl)-alpha-propylene; p-Allylphenol; p-Chavicol; Phenol, 4-(2-propenyl)-; Phenol, p-allyl-. Grades: 95%. CAS No. 501-92-8. Molecular formula: C9H10O. Mole weight: 134.18.
Palmatine hydrochloride
Palmatine hydrochloride (Palmatine chloride) is a hydrochloride salt of palmatine, a protoberberine alkaloid that has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases. It acts as an inhibitor of dopamine generation which reduces Ca2+ levels. Synonyms: Palmatine chloride; 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride. Grades: ≥98% (HPLC). CAS No. 10605-02-4. Molecular formula: C21H22ClNO4. Mole weight: 387.86.
Palmatrubine
Palmatrubine is an alkaloid isolated from the herbs of Tinospora sagittata. Synonyms: Dibenzo[a,g]quinolizinium, 5,6-dihydro-9-hydroxy-2,3,10-trimethoxy-. Grades: >98%. CAS No. 16176-68-4. Molecular formula: C20H20NO4. Mole weight: 338.4.
Palmitoleoyl 3-carbacyclic phosphatidic acid
Palmitoleoyl 3-carbacyclic phosphatidic acid is a cyclic LPA analog containing the 16:1 fatty acid, palmitoleate, at the sn-1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (86.9%) or LPA (99.9%) without affecting proliferation. It has been shown to inhibit autotaxin (IC50 = 620 nM). Synonyms: 3-carbacyclic PA; 3-ccPA 16:1. Grades: ≥95%. CAS No. 910228-13-6. Molecular formula: C20H37O5P. Mole weight: 388.5.
Palmitoyl 3-carbacyclic phosphatidic acid
Palmitoyl 3-carbacyclic phosphatidic acid is a cyclic LPA analog containing the 16:0 fatty acid, palmitate, at the sn-1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (81.9%) or LPA (98.9%) without affecting proliferation. It has been shown to inhibit autotaxin (IC50 = 620 nM). Synonyms: 3-ccPA 16:0. Grades: ≥95%. CAS No. 476310-22-2. Molecular formula: C20H39O5P. Mole weight: 390.5.
Palmitoyl-D-carnitine chloride
Palmitoyl-D-carnitine is a long-chain acylcarnitine. It inhibits carnitine palmitoyltransferase. Synonyms: Hexadecanoyl-D-carnitine; D-Hexadecanoylcarnitine; D-Palmitoylcarnitine; [(2S)-3-carboxy-2-hexadecanoyloxypropyl]-trimethylazanium chloride. Grades: ≥98%. CAS No. 28330-02-1. Molecular formula: C23H46NO4·Cl. Mole weight: 436.07.
Palmitoylethanolamide is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. It is a weak ligand of the cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptors, and a selective GPR55 agonist (EC50 values are 4, 19 800 and > 30 000 nM at GPR55, CB2 and CB1 receptors respectively). Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: N-(2-Hydroxyethyl)hexadecanamide; Palmidrol; PEA. Grades: ≥98% (HPLC). CAS No. 544-31-0. Molecular formula: C18H37NO2. Mole weight: 299.5.
Palmitoyl hexapeptide-12
Palmitoyl hexapeptide-12 is a lipopeptide used in cosmetics. Synonyms: Palmitoyl Hexapeptide; Lipopeptide Acetate; Palmitoyl Oligopeptide; palmitoyl-Val-Gly-Val-Ala-Pro-Gly-OH. Grades: 90%. CAS No. 171263-26-6. Molecular formula: C38H68N6O8. Mole weight: 737.
Palmitoyl-L-carnitine chloride
Palmitoyl-L-carnitine is a long-chain acylcarnitine. It inhibits lecithin:cholesterol acyltransferase activity in rat. Synonyms: Hexadecanoyl-L-carnitine; L-Hexadecanoylcarnitine; L-Palmitoylcarnitine; [(2R)-3-carboxy-2-hexadecanoyloxypropyl]-trimethylazanium chloride. Grades: ≥95%. CAS No. 18877-64-0. Molecular formula: C23H46NO4·Cl. Mole weight: 436.07.
Palmitoyl pentapeptide-4/Palmitoyl pentapeptide-3
Palmitoyl pentapeptide-4 is a matrikine modulating cell activities. Palmitoyl pentapeptide-4 exhibits anti-wrinkle activity and is used in the cosmetics. Synonyms: N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine. Grades: 98% by HPLC. CAS No. 214047-00-4. Molecular formula: C39H75N7O10. Mole weight: 802.05.
Palmitoyl Tetrapeptide-3
Palmitoyl tetrapeptide-7 is a synthetic peptide used for skin care and anti-aging cosmetics. Synonyms: Rigin; palmitoyl-Gly-Gln-Pro-Arg-OH; Palm-GQPR; N-palmitoyl-glycyl-L-glutaminyl-L-prolyl-L-arginine; Palmitoyl tetrapeptide-7; N-Palmitoylrigin. Grades: ≥98%. CAS No. 221227-05-0. Molecular formula: C34H62N8O7. Mole weight: 694.91.
Palmitoyl tripeptide-1
Palmitoyl tripeptide-1 is a type I collagen fragment used to repair skin damage. Synonyms: L-Lysine, N-(1-oxohexadecyl)glycyl-L-histidyl-; Palmitoyl-glycyl-histidyl-lysine; palmitoyl oligopeptide; Pal-GHK. CAS No. 147732-56-7. Molecular formula: C30H54N6O5. Mole weight: 578.799.
Palmitoyl Tripeptide-38
Palmitoyl Tripeptide-38 is a synthetic peptide used for skin care. Synonyms: Palmitoyl Tripeptide 38; matrixyl synthe'6. CAS No. 1447824-23-8.
Palmitoyl tripeptide-5 triflate
Palmitoyl tripeptide-5 triflate is a component of cell transduction, and promotes the production of collagen. It is commonly used in anti-aging and anti-wrinkle cosmetics. Synonyms: (S)-6-Amino-2-((S)-2-((S)-6-amino-2-palmitamidohexanamido)-3-methylbutanamido)hexanoic acid compound with 2,2,2-trifluoroacetic acid (1:2); Palmitoyl tripeptide-5 bistrifluoracetate salt. CAS No. 623172-56-5. Molecular formula: C37H67F6N5O9. Mole weight: 839.959.
Pamabrom
Pamabron is a common over-the-counter diuretic used for relief of menstrual-associated symptoms. It is available in combination with acetaminophen for various conditions such as back pain and menstrual relief. The active diuretic ingredient in pamabrom is 8-bromotheophylline. Grades: >98%. CAS No. 606-04-2. Molecular formula: C11H18BrN5O3. Mole weight: 348.2.
Pamidronate Disodium
Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate is a nitrogen-containingbisphosphonate, used to prevent osteoporosis. Grades: >98%. CAS No. 57248-88-1. Molecular formula: C3H9NNa2O7P2. Mole weight: 279.03.
Pamiparib
Pamiparib is a potent and selective inhibitor of PARP1/PARP2 displaying anticancer activity. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: BGB-290. CAS No. 1446261-44-4. Molecular formula: C16H15FN4O. Mole weight: 298.31.
Pamoic acid disodium salt
Pamoic acid disodium salt is an activator of GPR35 by mediating recruitment of β-arrestin2, with antinociceptive effects in a mouse model of visceral pain. It induces GPR35 internalization and activates ERK1/2 (EC50= 22 and 65 nM respectively). Synonyms: 4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic acid) disodium salt. Grades: ≥99% by HPLC. CAS No. 6640-22-8. Molecular formula: C23H14Na2O6. Mole weight: 432.33.
PAMP-12 (human, porcine)
PAMP-12 is an endogenous peptide agonist of Mas related GPR X2 (MRGPRX2). Synonyms: PAMP-12 (human, porcine); 196305-05-2; Adrenomedullin, 9-20-pro- (swine); PAMP (9-20); AKOS034834089; PD080401. CAS No. 196305-05-2. Molecular formula: C77H119N25O14. Mole weight: 1618.95.
Panaxcerol C
Monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) are the two nonionic lipid constituents of the thylakoid membrane of higher plant chloroplasts. MGDG and DGDG are present in the membrane at 56% and 29%, respectively, of the total lipid content. DGDG is a bilayer-forming lipid, while MGDG alone will only form hexagonal-II structures. Synonyms: Monogalactosyldiacylglycerol (Plant); 1,2-diacyl-3-O-β-D-galactosyl-sn-glycerol; MGDG; 1-18:3-2-18:3-Monogalactosyldiacylglycerol; 18:3-18:3-MGDG; 1,2-Di-O-alpha-linolenoyl-3-O-beta-galactopyranosyl-sn-glycerol; 1,2-(9Z,12Z,15Z-octadecatrienoyl)-3-O-beta-D-galactosyl-sn-glycerol; (9Z,9'Z,12Z,12'Z,15Z,15'Z)-(S)-3-(((2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propane-1,2-diyl bis(octadeca-9,12,15-trienoate); β-D-Galactopyranoside, (2S)-2,3-bis[[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]oxy]propyl. Grades: >95%. CAS No. 63180-02-9. Molecular formula: C45H74O10. Mole weight: 775.06.
Pangelin
Pangelin is found in the roots of Angelica dahurica. Synonyms: R-(+)-Pangelin. Grades: > 95%. CAS No. 33783-80-1. Molecular formula: C16H14O5. Mole weight: 286.28.
Panobinostat
Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (VEGF), thus impairing endothelial cell chemotaxis and invasion. HDAC is an enzyme that deacetylates chromatin histone proteins. Uses: Antineoplastic agents. Synonyms: LBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; trade name Farydak. Grades: >98%. CAS No. 404950-80-7. Molecular formula: C21H23N3O2. Mole weight: 349.434.
Pan-RAS-IN-1
Pan-RAS-IN-1 is a pan-Ras inhibitor and exhibits lethality in cells partially dependent on expression of Ras proteins. Synonyms: RasIN3144; Ras IN-3144; Ras-IN 3144; Ras-IN-3144; 3144; pan-RAS inhibitor-3144; 4-amino-N-[3-[5-[[4-[(2,6-dichlorophenyl)methyl]piperazin-1-yl]methyl]-3-[4-(trifluoromethoxy)phenyl]indol-1-yl]propyl]piperidine-4-carboxamide. CAS No. 1835283-94-7. Molecular formula: C36H41Cl2F3N6O2. Mole weight: 717.65.
Pantoprazole
Pantoprazole, an irreversible protonpump inhibitor, inhibits the final step of the production ofgastric acid by binding to the sites of H+/K+ ATPase system in gastric parietal cells. Uses: Pantoprazole, an irreversible protonpump inhibitor, inhibits the final step of the production ofgastric acid by binding to the sites of h+/k+ atpase system in gastric parietal cells. Synonyms: Pantoprazole; BY 1023; BY-1023; SK&F 96022; SK&F-96022; Protonix; 102625-70-7; Pantozol; PantoprazoleSodium; Pantoprazolum. Grades: 95%. CAS No. 102625-70-7. Molecular formula: C16H15F2N3O4S. Mole weight: 383.37.
Pantoprazole EP Impurity E
Pantoprazole EP Impurity E is an impurity of Pantoprazole, a first-generation proton pump inhibitor (PPI) used as a drug for the treatment of gastroesophageal reflux disease (GERD). Synonyms: 6,6'-Bis(difluoromethoxy)-2,2'-bis(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)-3H,3'H-5,5'-bibenzo[d]imidazolel; USP Pantoprazole Related Compound E; Pantoprazole Related Compound E. Grades: > 95%. CAS No. 2115779-15-0. Molecular formula: C32H28F4N6O8S2. Mole weight: 764.72.
p-APMSF hydrochloride
p-APMSF is a specific and irreversible inhibitor of plasma serine proteases. It causes immediate and complete irreversible inhibition of bovine trypsin and human thrombin. Synonyms: (p-Amidinophenyl)methanesulfonyl fluoride hydrochloride; para-APMSF hydrochloride; 4-Amidinophenylmethanesulfonyl fluoride hydrochloride; (4-carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride. Grades: ≥95%. CAS No. 74938-88-8. Molecular formula: C8H9FN2O2S·HCl. Mole weight: 252.69.
paramethadione
This active molecular is an an antiepileptic and anticonvulsant agent. It is associated with fetal trimethadione syndrome that is also called as paramethadione syndrome. Uses: As an antiepileptic and anticonvulsant agent. Synonyms: 3,5-Dimethyl-5-ethyloxazolidine-2,4-dione; 5-Ethyl-3,5-dimethyloxazolidine-2,4-dione; Paradione. Grades: 98%. CAS No. 115-67-3. Molecular formula: C7H11NO3. Mole weight: 157.17.
Parathyroid hormone (1-34) (bovine)
Parathyroid hormone (1-34) (bovine) is a parathyroid hormone (PTH) receptor agonist. It increases calcium and inorganic phosphate levels in the serum of young rats. Parathyroid hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid, which is secreted by the chief cell of the parathyroid glands as a polypeptide containing 84 amino acids. Synonyms: L-Phenylalanine, L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-phenylalanyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-seryl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-;; Ala-Val-Ser-Glu-Ile-Gln-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe. CAS No. 12583-68-5. Molecular formula: C183H288N54O50S2. Mole weight: 4108.74.
Parathyroid hormone (1-34) (rat)
Parathyroid hormone (1-34) (rat), a synthetic, rat parathryroid hormone, is a parathyroid hormone (PTH) receptor agonist, which increases serum PTH levels and bone mass in rats. Synonyms: pTH (1-34) (rat). CAS No. 98614-76-7. Molecular formula: C180H291N55O48S2. Mole weight: 4057.74.
Parbendazole
Parbendazole, a benzimidazole carbamat used as an antinematodal agent, is a potent inhibitor of microtubule assembly and functions. Synonyms: methyl N-(6-butyl-1H-benzimidazol-2-yl)carbamate; N-(6-Butyl-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester; 5-Butyl-2-(carbomethoxyamino)benzimidazole; Helatac; Helmatac; Methyl (5-butyl-1H-benzimidazol-2-yl)carbamate; Methyl 5(6)-butyl-2-benzimidazolecarbamate; Methyl 5-butylbenzimidazole-2-carbamate; PBZ; PBZ (fungicide); Parbendazole; SKF 29044. CAS No. 14255-87-9. Molecular formula: C13H17N3O2. Mole weight: 247.29.
Paricalcitol Impurity 1
An impurity of Paricalcitol which is a man-made form of vitamin D to treat and prevent high levels of a certain natural substance made by the body (parathyroid hormone) in patients with long-term kidney disease. Synonyms: 22-Z-Paricalcitol; (1R,3R)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5S,Z)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol. Grades: > 95%. CAS No. 1884139-61-0. Molecular formula: C27H44O3. Mole weight: 416.65.
Paricalcitol Impurity 4
Paricalcitol Impurity 4 is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: PRC-2; (1R,3aR,7aR)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-one. CAS No. 95716-68-0. Molecular formula: C19H32O2. Mole weight: 292.463.
Paricalcitol Intermediate A
Paricalcitol Intermediate A is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: tert-butyl-[ (1R, 3R) -3-[tert-butyl (dimethyl) silyl]oxy-5- (2-diphenylphosphorylethylidene) cyclohexyl]oxy-dimethylsilane. CAS No. 139356-39-1. Molecular formula: C32H51O3PSi2. Mole weight: 570.901.
Paricalcitol Intermediate CD
Paricalcitol Intermediate CD is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Synonyms: (1R,3aR,7aR)-1-[(E,2R,5S)-5,6-dimethyl-6-trimethylsilyloxyhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-one. CAS No. 95716-69-1. Molecular formula: C22H40O2Si. Mole weight: 364.645.
Paroxetine EP Impurity G
An impurity of Paroxetine, which is a selective serotonin reuptake inhibitor. Synonyms: 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine; Pyridine, 4-(4-fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-. CAS No. 69675-10-1. Molecular formula: C12H14FN. Mole weight: 191.24.
Paroxetine hydrochloride hemihydrate
Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Uses: Selective serotonin reuptake inhibitors. Synonyms: Paroxetine hydrochloride hemihydrate; 110429-35-1; UNII-X2ELS050D8X2ELS050D8(; 3S, 4R)-3-(1, 3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine; hydrate; dihydrochloride. Grades: >98%. CAS No. 110429-35-1. Molecular formula: C19H23ClFNO4. Mole weight: 383.3.
Paroxetine Impurity G HCl
An impurity of Paroxetine which is an antidepressant to treat diseases like depression, obsessive-compulsive disorder, anxiety disorders. Synonyms: 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride; 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine Hydrochloride; 1-Methyl-4-(4'-fluorophenyl)-1,2,3,6-tetrahydropyridine Hydrochloride; Paroxetine EP Impurity G. Grades: > 95%. CAS No. 1012886-75-7. Molecular formula: C12H14FN.HCl. Mole weight: 227.71.