BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
(Cys26)-Amyloid β-Protein (1-40) (Dimer) is a dimer of (Cys26)-Aβ40. Synonyms: Amyloid β-Protein (1-40) S26C (Dimer); (H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Cys-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH)2 (Disulfide bond). Grade: ≥95%. CAS No. 1802087-75-7. Molecular formula: C388H588N106O114S4. Mole weight: 8689.85.
[Cys58]105Y, α1-antitrypsin (358-374)
It is a synthetic peptide based on the sequence corresponding to residues 359 to 374 of α1-antitrypsin. C105Y can penetrate cell membrane rapidly, enter the cytoplasm, and localize to the nucleus and nucleolus of live culture cells. C105Y peptide enters the nucleolus very rapidly in an energy-dependent manner. Membrane transport and nuclear localization are energy-independent. It enhances gene expression in DNA nanoparticles. Synonyms: Cys-Ser-Ile-Pro-Pro-Glu-Val-Lys-Phe-Asn-Lys-Pro-Phe-Val-Tyr-Leu-Ile. Grade: >98%. Molecular formula: C97H148N20O23S. Mole weight: 1994.43.
(Cys-Aca)-Bombesin (7-14)
(Cys-Aca)-Bombesin (7-14) is a derivative of Bombesin (7-14) that can be used in detection of prostate cancer highly expressing GRPR. Synonyms: Cys-Aca-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2. Molecular formula: C52H81N15O11S2. Mole weight: 1156.50.
(Cysteinol7,des-L-threoninol8)-Octreotide is an impuritiy of octreotide. Synonyms: H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-cysteinol (Disulfide bridge: Cys2-Cys7); Octreotide Impurity 8; Octreotide Acetate Impurity 11. Grade: ≥95%. CAS No. 1546983-18-9. Molecular formula: C45H59N9O8S2. Mole weight: 918.14.
(D-Ala18)-Liraglutide trifluoroacetate salt
(D-Ala18)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-D-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C172H265N43O51.C2HF3O2. Mole weight: 3865.21.
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
DAMGO is an analog of μ-Receptor-specific enkephalin. It stimulates calcium-activated adenylyl cyclases related cAMP production. Synonyms: DAMGO acetate; DAGO acetate; Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol; L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide monoacetate (salt); L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-alpha-methyl-L-phenylalaninamide monoacetate (salt). Grade: 95%. CAS No. 100929-53-1. Molecular formula: C28H39N5O8. Mole weight: 573.64.
(D-Arg)2, Icatibant impurity
(D-Arg)2, Icatibant impurity is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: (D-Arg)-(D-Arg)-Pro-Hyp-Gly-Thi-Ser-(D-Tic)-Oic-Arg; D-Arg-D-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg. Molecular formula: C59H89N19O13S. Mole weight: 1304.50.
(D-Arg8)-Inotocin
(D-Arg8)-Inotocin is the insect neuropeptide inotocin analog similar to the human vasopressin V1a receptor antagonist. Synonyms: [D-Arg8]-Inotocin; H-Cys-Leu-Ile-Thr-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6). CAS No. 745816-74-4. Molecular formula: C39H68N14O11S2. Mole weight: 973.18.
(D-Arg)9
(D-Arg)9 belongs to cell-penetrating peptides (CPPs) characterized by promoting receptor-independent cell uptake of membrane-impermeable macromolecules, such as peptides, proteins, nucleic acids, and nanoparticles. It is a poly-Arg peptide comprising of 9 D-Arginine residues. Synonyms: H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-OH; D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginine; Nona-D-Arginine. Grade: >98%. Molecular formula: C54H110N36O10. Mole weight: 1423.72.
(D-Arginine)-9, also known as D-polyarginine or nona-D-arginine, is a peptide made of D-amino acids. It's used as a cell penetrating peptide (CPP) to deliver cargo across cell membranes. Synonyms: (D-Arg)-(D-Arg)-(D-Arg)-(D-Arg)-(D-Arg)-(D-Arg)-(D-Arg)-(D-Arg)-(D-Arg). Molecular formula: C54H110N36O10. Mole weight: 1423.72.
(D-Asn28)-Exenatide
(D-Asn28)-Exenatide is a potential impurity of exenatide. Synonyms: (D-Asn28)-Exendin-4; H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-D-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Grade: ≥95%. CAS No. 2022972-66-1. Molecular formula: C184H282N50O60S. Mole weight: 4186.63.
(D-Asp28)-Exenatide
(D-Asp28)-Exenatide is a potential degradation product of exenatide produced by the formation and cleavage of aspartimide. Synonyms: H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-D-Asp-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Grade: ≥95%. CAS No. 2022972-67-2. Molecular formula: C184H281N49O61S. Mole weight: 4187.62.
DBCO-PEG4-vc-PAB-MMAF is a drug-linker conjugate for ADC by using Monomethylauristatin F (MMAF, a potent tubulin polymerization inhibitor), linked via DBCO-PEG4-vc-PAB. Molecular formula: C88H126N12O20. Mole weight: 1672.04.
DC-1
DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Synonyms: (S)-5-amino-N-(2-(1-(chloromethyl)-5-hydroxy-2,3-dihydro-1H-benzo[e]indole-3-carbonyl)-1H-indol-5-yl)-1H-indole-2-carboxamide. Grade: ≥95%. Molecular formula: C31H24ClN5O3. Mole weight: 550.01.
(d(CH2)51,D-Ile2,Ile4,Arg8,Tyr9)-Vasopressin
(d(CH2)51,D-Ile2,Ile4,Arg8,Tyr9)-Vasopressin is an AVP antagonist specifically targeting rat V2 receptors. The amino acid type at position 2 controls rat versus human selectivity to AVP analogues. Synonyms: d(CH2)5[D-Ile2,Ile4,Tyr9]-AVP; β-Mercapto-β,β-cyclopentamethylene-propionyl-D-Ile-Phe-Ile-Asn-Cys-Pro-Arg-Tyr-NH2 (Disulfide bridge: Cys1-Cys6); (d(CH2)51,D-Ile2,Ile4,Arg8,Tyr9)-Vasopressin. CAS No. 114438-90-3. Molecular formula: C56H83N13O11S2. Mole weight: 1178.47.
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin is a selective vasopressin V1A receptor antagonist. Synonyms: Manning Compound, [Pmp1, Tyr(OMe)2, Arg8] Vasopressin; β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 trifluoroacetate salt (Disulfide bond). Grade: >98%. CAS No. 73168-24-8. Molecular formula: C52H74N14O12S2. Mole weight: 1151.38.
(d(CH2)51,Tyr(Me)2,Dab5,Arg8,Tyr9)-Vasopressin
Asn5 can be replaced by isosteric Dab to produce a vasopressin antagonist. Synonyms: d(CH2)5[Tyr(Me)2,Dab5,Arg8,Tyr9]-AVP; β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Dab-Cys-Pro-Arg-Tyr-NH2 (Disulfide bridge: Cys1-Cys6); (d(CH2)51,Tyr(Me)2,Dab5,Arg8,Tyr9)-Vasopressin. Grade: ≥90%. Molecular formula: C59H82N14O12S2. Mole weight: 1243.50.
(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
Dab isosteric substitution of Asn5 inevitably leads to a significant loss of peptide bioactivity in oxytocin, vasopressin and their analogs. In OT or VP antagonists, the exchange produces highly selective and potent OT and V1a receptor antagonists. Synonyms: d(CH2)5[Tyr(Me)2,Dab5,Arg8]-AVP; (d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin; β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Dab-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); [d(CH2)5,Tyr(Me)2,Dab5]AVP. CAS No. 176714-12-8. Molecular formula: C52H76N14O11S2. Mole weight: 1137.38.
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin is a potent and selective oxytocin antagonist in vivo. Synonyms: dGVTA; β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-OH; OTA (dOVT); 2-O-methyltyrosyl-4-threonyl-8-ornithyl-9-desglycinamide-vasotocin; desGly(9)-d(CH2)5(Tyr(Me)(2)-Thr(4))OVT; (1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid),2-O-methyltyrosine,4-threonine,8-ornithine)vasotocin; Methyl N-[(2-thioxocyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithinate; L-Ornithine, N-[2-(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-, cyclic (1→5)-disulfide; (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin. Grade: ≥95% by HPLC. CAS No. 115499-13-3. Molecular formula: C45H69N9O12S2. Mole weight: 992.21.
(D-Cys7,des-L-threoninol8)-Octreotide
(D-Cys7,des-L-threoninol8)-Octreotide is a potential impurity of octreotide. Synonyms: H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-OH (Disulfide bridge: Cys2-Cys7). Molecular formula: C45H57N9O9S2. Mole weight: 932.12.
(D-Cys)7 Eptifibatide impurity
(D-Cys)7 Eptifibatide impurity is an impurity of Eptifibatide, which is an antiplatelet drug of glycoprotein IIb/IIIa inhibitor. Synonyms: Mpr-(Homo-Arg)-Gly-Asp-Trp-Pro-(D-Cys)-NH2 (Disulfide bond Mpr1/Cys7); Mpr-hArg-Gly-Asp-Trp-Pro-D-Cys-NH2 (Disulfide bond Mpr1/Cys7). Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
(Deamino-Cys1,β-cyclohexyl-Ala4,Dab8)-Vasopressin
The introduction of Cha produces agonists for human V1b receptors. Synonyms: d[Cha4,Dab8]-AVP; 3-Mercaptopropionyl-Tyr-Phe-β-cyclohexyl-Ala-Asn-Cys-Pro-Dab-Gly-NH2 (Disulfide bridge: Cys1-Cys6); deamino-Cys(1)-Tyr-Phe-Cha-Asn-Cys(1)-Pro-Dab-Gly-NH2; deamino-cysteinyl-L-tyrosyl-L-phenylalanyl-3-cyclohexyl-L-alanyl-L-asparagyl-L-cysteinyl-L-prolyl-3-aminomethyl-L-alanyl-glycinamide (1->6)-disulfide; d[Cha4,Dab8]VP; N-{(2S)-4-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxobutan-2-yl}-1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-(cyclohexylmethyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolinamide. Grade: ≥90%. CAS No. 929294-77-9. Molecular formula: C48H67N11O11S2. Mole weight: 1038.25.
(Deamino-Cys1,Lys8)-Oxytocin
Desamino-LVT exhibits oxytocin activity of Lysine-vasotocin, but no pressor activity. Synonyms: dOTK8; 3-Mercaptopropionyl-Tyr-Ile-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); deamino-Cys(1)-Tyr-Ile-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2; deamino-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; 1-{[(4R,7S,10R,13S,16R)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2R)-2-butanyl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-D-prolyl-L-lysylglycinamide. Grade: ≥90%. CAS No. 25529-45-7. Molecular formula: C43H66N12O12S2. Mole weight: 1007.19.
(Deamino-Cys1,Tyr(Me)2,Val4,D-Arg8)-Vasopressin
(Deamino-Cys1,Tyr(Me)2,Val4,D-Arg8)-Vasopressin is a potent and highly specific antidiuretic AVP agonist. Synonyms: d[Tyr(Me2)]VdAVP; 3-Mercaptopropionyl-Tyr(Me)-Phe-Val-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); vasopressin, 1-deamino-(2-(O-methyl)Tyr)-4-Val-8-Arg-; 1-deamino-(2-O-methyltyrosine,4-valine,8-D-arginine)vasopressin; deamino-Cys(1)-Tyr(Me)-Phe-Val-Asn-Cys(1)-Pro-D-Arg-Gly-NH2; deamino-cysteinyl-O4-methyl-L-tyrosyl-L-phenylalanyl-L-valyl-L-asparagyl-L-cysteinyl-L-prolyl-D-arginyl-glycinamide (1->6)-disulfide. Grade: ≥90%. CAS No. 85114-98-3. Molecular formula: C47H67N13O11S2. Mole weight: 1054.25.
δ-Tocotrienol
δ-Tocotrienol is from palm oil. Delta-tocotrienol is a potential angiogenic inhibitor that significantly suppresses human colorectal adenocarcinoma cells (DLD-1-CM)-induced tube formation, migration, and adhesion on human umbilical vein endothelial cells. Delta-tocotrienol is a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offer a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects that protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. Synonyms: [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,8-Dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (R)-δ-Tocotrienol; 8-Methyltocotrienol; d-δ-Tocotrienol. Grade: 95%. CAS No. 25612-59-3. Molecular formula: C27H40O2. Mole weight: 396.60.
(Des-acetyl)-alpha-MSH is an antimicrobial peptide produced by Homo sapiens. It has antibacterial and antifungal activity. Synonyms: Alpha-MSH; Sequence 3 from Patent US 7244710; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2. Grade: 96%. Molecular formula: C75H107N21O18S. Mole weight: 1622.87.
[Des-Arg9]-Bradykinin acetate
[Des-Arg9]-Bradykinin acetate is a selective Bradykinin(B1) receptor agonist and increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-OH.CH3CO2H; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanine acetic acid; 9-De-arg-bradykinin acetate; 9-Des-arg-BK acetate; Des-arg(9)-bradykinin acetate; 9-de-L-Argininebradykinin acetate; 1-8-Bradykinin acetate. Grade: ≥95%. CAS No. 23827-91-0. Molecular formula: C46H65N11O12. Mole weight: 964.07.
(Des-Asp1)-Angiotensin I
(Des-Asp1)-Angiotensin I. Synonyms: Angiotensin I [Des-Asp1-](human); H-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH. CAS No. 56317-01-2. Molecular formula: C58H84N16O11. Mole weight: 1181.39.
(Des-Glu22)-Amyloid β-Protein (1-40)
Osaka mutation is the first deletion type mutation found in APP and Aβ. Aβ E22delta mutant is more resistant to degradation of two major Aβ-degrading enzymes, neprilysin and insulin-degrading enzyme. The synthetic mutant Aβ has unusual aggregation properties, with enhanced oligomerization but no fibrillization. It inhibits long-term hippocampal enhancement more effectively than wild-type Aβ. Synonyms: Amyloid β-Protein (1-40) Osaka or Japanese Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH. Grade: ≥95%. CAS No. 1678416-36-8. Molecular formula: C189H288N52O55S. Mole weight: 4200.75.
(Des-Glu22)-Amyloid β-Protein (1-42)
(Des-Glu22)-Amyloid β-Protein (1-42), the Osaka (E22delta) mutation of Amyloid β, promotes β-sheet transformation, free radical production, and synaptic toxicity, but is not neurotoxic. Synonyms: Amyloid β-Protein (1-42) Japanese Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grade: ≥95%. CAS No. 1239313-74-6. Molecular formula: C198H304N54O57S. Mole weight: 4384.99.
(Des-Gly29)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C170H262N42O50.C2HF3O2. Mole weight: 3808.16.
(Des-Gly2)-Exenatide
(Des-Gly2)-Exenatide is a potential impurity of exenatide. Synonyms: (Des-Gly2)-Exendin-4; H-His-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Grade: ≥95%. CAS No. 1678416-78-8. Molecular formula: C182H279N49O59S. Mole weight: 4129.58.
(Des-Gly31)-Liraglutide trifluoroacetate salt
(Des-Gly31)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-OH trifluoroacetate salt. Molecular formula: C170H262N42O50.C2HF3O2. Mole weight: 3808.16.
[Des-octanoyl]-Ghrelin (human) is a major circulating form of ghrelin. It inhibits cell proliferation in breast and prostate cancer cell lines. Synonyms: Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg. CAS No. 313951-59-6. Molecular formula: C141H235N47O41. Mole weight: 3244.70.
(Des-Pro3, Hyp4) Icatibant impurity
(Des-Pro3, Hyp4) Icatibant impurity is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: Des[Pro(3)-Hyp(4)]-Icatibant; (D-Arg)-Arg-Gly-Thi-Ser-(D-Tic)-Oic-Arg; D-Arg-Arg-Gly-Thi-Ser-D-Tic-Oic-Arg. Molecular formula: C49H75N17O10S. Mole weight: 1094.2.
(Des-Ser8)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C169H260N42O49.C2HF3O2. Mole weight: 3778.14.
(D-His1)-Exenatide is an impurity of exenatide. Synonyms: (D-His1)-Exendin-4; H-D-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Grade: ≥95%. CAS No. 1678417-09-8. Molecular formula: C184H282N50O60S. Mole weight: 4186.63.
(D-Hyp)4, Icatibant impurity is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: (D-Arg)-Arg-Pro-(D-Hyp)-Gly-Thi-Ser-(D-Tic)-Oic-Arg; D-Arg-Arg-Pro-D-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg. Molecular formula: C59H89N19O13S. Mole weight: 1304.50.
(-)-DIOP
(-)-DIOP is a chiral phosphine ligand for enantioselective synthesis with high yield and high enantioselective results. Synonyms: (4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane. Grade: 98%. CAS No. 32305-98-9. Molecular formula: C31H32O2P2. Mole weight: 498.53.
Diphenyl(trifluoromethyl)sulfonium trifluoromethanesulfonate can be used as a raw material for organic synthesis with styrene derivatives to synthesise 2-arylazo pyridine at low temperature. Synonyms: Sulfonium, diphenyl(trifluoromethyl)-, 1,1,1-trifluoromethanesulfonate (1:1); Diphenyl-(trifluoromethyl)-sulfonium trifluoromethanesulfonate. Grade: 98%. CAS No. 147531-11-1. Molecular formula: C14H10F6O3S2. Mole weight: 404.35.
DM1 with a reactive linker SPP, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. Synonyms: N2'-deacetyl-N2'-[3-[[4-[(2,?5-dioxo-1-pyrrolidinyl)?oxy]?-1-methyl-4-oxobutyl]?dithio]?-1-oxopropyl]?-Maytansine; DM1 SPP. Grade: ≥98%. CAS No. 452072-20-7. Molecular formula: C44H59ClN4O14S2. Mole weight: 967.54.
DM3
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. Synonyms: N2'-deacetyl-N2'-(4-mercapto-1-oxopentyl)- maytansine. Grade: ≥95%. CAS No. 796073-54-6. Molecular formula: C37H52ClN3O10S. Mole weight: 766.34.
DM3-SMe
DM3-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Synonyms: N2'-deacetyl-N2'-[4-(R,S)-(methyldithio)-1-oxopentyl]maytansine. Grade: ≥98%. CAS No. 796073-70-6. Molecular formula: C38H54ClN3O10S2. Mole weight: 812.43.
DM4-SMe
DM4-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). Synonyms: N2'-deacetyl-N2'-[4-methyl-4-(methyldithio)-1-oxopentyl]maytansine. Grade: ≥98%. CAS No. 796073-68-2. Molecular formula: C39H56ClN3O10S2. Mole weight: 826.46.
DM4-SPDB
DM4 with a reactive linker SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Synonyms: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2 S)-2-{[4-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}disulfanyl)-4-methylpentanoyl](methyl)amino}propanoate (non-preferred name); DM4 SPDB. Grade: ≥98%. CAS No. 1626359-62-3. Molecular formula: C46H63ClN4O14S2. Mole weight: 995.59.
DM4-SPDP
DM4 with a reactive linker SPDP, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Synonyms: Maytansinoid DM4- succinimidyl 3-(2-pyridyldithio)propionate; DM4 SPDP. Grade: ≥98%. CAS No. 2245698-48-8. Molecular formula: C45H61ClN4O14S2. Mole weight: 981.57.
(D-Met)14, Exendin-4
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-(D-Met)-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C184H282N50O60S. Mole weight: 4186.56.
DMRIE
DMRIE is a quaternary ammonium compound with surfactant properties. It features a hydrophilic head with dimethyl and hydroxyethyl groups, and two hydrophobic tetradecyl (C14) alkyl chains, making it effective in forming micelles and emulsifying agents. The bromide counterion balances the charge of the ammonium group. This compound is commonly used in formulations requiring surfactants, such as in detergents, personal care products, and possibly in drug delivery systems due to its amphiphilic nature. Synonyms: N-(2-Hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)-1-propaniminium Bromide; 1-Propanaminium, N-(2-hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)-, bromide (1:1); Dimethyl-2-hydroxyethyl-2,3-ditetradecyloxypropylammonium bromide; Dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium; N-[1-(2,3-Ditetradecyloxy)propyl]-N,N-dimethyl-N-hydroxyethylammonium bromide; N-(2-Hydroxyethyl)-N,N-dimethyl-2,3-bis(tetradecyloxy)propan-1-aminium bromide. Grade: ≥95%. CAS No. 153312-64-2. Molecular formula: C35H74BrNO3. Mole weight: 636.87.
Docosan-1-amine is a drug substance that belongs to the class of monocarboxylic acids. Synonyms: 1-Docosanamine; Docosylamine; docosanylamine. Grade: 95% by NMR. CAS No. 14130-06-4. Molecular formula: C22H47N. Mole weight: 325.62.
Docosanedioic acid
Behenic acid, or docosanedioic acid, a saturated fatty acid, is an effective emollient in the cosmetics industry due to its remarkable moisturizing properties. Behenic acid's therapeutic potential is another aspect of interest, as it has been researched for the treatment of various maladies, including multiple sclerosis and Parkinson's disease. Moreover, it is demonstrated to have a positive impact on chondrogenesis, which is vital for the formation of cartilage tissue due to its exceptional proliferative force. It is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker. Synonyms: Felogenic acid; Phellogenic acid; 1,22-Docosanedioic acid; 1,20-Eicosanedicarboxylic acid; Docosan-1,22-dioic acid. Grade: 95%. CAS No. 505-56-6. Molecular formula: C22H42O4. Mole weight: 370.57.