BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| N-Acetyl-L-cysteine | N-Acetyl-L-cysteine is an antioxidant and precursor to glutathione. It has potential anticancer activity against tumor cell growth. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Acetylcysteine; N-Acetylcysteine; Mercapturic acid; Acetadote; (2R)-2-acetamido-3-sulfanylpropanoic acid. Grades: 95%. CAS No. 616-91-1. Molecular formula: C5H9NO3S. Mole weight: 163.19. |  |
| N-Acetyl-L-cysteine ethyl ester | N-Acetyl-L-cysteine ethyl ester, a derivative of N-acetylcysteine, is acknowledged for its highly efficacious anti-inflammatory and antioxidant properties. This potent compound has been employed in numerous treatments, including those for cystic fibrosis and HIV-associated neuropathy. Apart from that, it is widely consumed as a dietary supplement due to its potentiality in enhancing liver and lung health. Synonyms: L-Cysteine, N-acetyl-, ethyl ester; Ethyl (2R)-2-acetamido-3-sulfanylpropanoate. CAS No. 59587-09-6. Molecular formula: C7H13NO3S. Mole weight: 191.245. | |
| N-Acetylneuraminic acid | N-Acetylneuraminic acid is a sialic acid monosaccharide found in glycoproteins and glycolipids on cell membranes. Synonyms: Sialic acid; NeuNAc; NANA; 5-(Acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic Acid; N-Acetylsialic Acid; 5-N-Acetyl-beta-D-neuraminic acid; N-Acetyl-D-neuraminic acid; N-acetyl-beta-neuraminic acid. Grades: ≥95%. CAS No. 131-48-6. Molecular formula: C11H19NO9. Mole weight: 309.27. | |
| N-Acetylneuraminic Acid Methyl Ester | Cas No. 22900-11-4. | |
| N-acetyl Selank | N-acetyl Selank is an analog of Selank, which is a nootropic and anxiolytic peptide drug peptide. Synonyms: L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-Proline. Grades: 98%. Molecular formula: C33H57N11O9. Mole weight: 751.89. | |
| N-acetyl semax | N-acetyl semax is a modified fragment of the corticotropin hormone. Synonyms: L-Methionyl-L-α-glutamylhistidyl-L-phenylalanyl-L-prolylglycyl-L-proline, (Pro8,Gly9,Pro10)ACTH-(4-10). Grades: 98%. Molecular formula: C37H51N9O10S. Mole weight: 813.92. | |
| N-acetyl-S-geranylgeranyl-L-cysteine | N-acetyl-S-geranylgeranyl-L-Cysteine is an inhibitor of the isoprenylated protein methyltransferase. Synonyms: AGGC; (2R)-2-acetamido-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]sulfanylpropanoic acid. Grades: ≥95%. CAS No. 139332-94-8. Molecular formula: C25H41NO3S. Mole weight: 435.7. | |
| NAD+, Lithium salt | NAD+, Lithium salt is the salt form of NAD+, which is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of several enzymes, such as poly(ADP)-ribose polymerases and cADP-ribose synthases. NAD+ is commonly used as an oxidizing agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: β-Nicotinamide adenine Dinucleotide, Li; Beta-NAD lithium salt; Nicotinamide adenine dinucleotide lithium salt. CAS No. 64417-72-7. Molecular formula: C21H26LiN7O14P2. Mole weight: 669.362. | |
| Nafamostat mesilate | Nafamostat Mesylate is a synthetic serine protease inhibitor and an anticoagulant. It is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate; Nafamostat mesylate; nafamostat mesilate; FUT-175; FUT 175; FUT175. Grades: >98%. CAS No. 82956-11-4. Molecular formula: C21H25N5O8S2. Mole weight: 539.58. | |
| Nafarelin | Synthetic gonadotropin-releasing hormone (GnRH) agonist that stimulates secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Repeated administration causes desensitization of pituitary GnRH receptors resulting in inhibition of gonadotropin release and decreased steroid hormone synthesis. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-2Nal-Leu-Arg-Pro-Gly-NH2. Grades: 98%. CAS No. 76932-56-4. Molecular formula: C66H83N17O13. Mole weight: 1322.47. | |
| Nafarelin Acetate | Nafarelin is a GnRH (gonadotropin-releasing hormone) agonist used for the treatment of precocious puberty in children and Premature LG surges. Synonyms: Luteinizing hormone-releasing factor (swine), 6-[3-(2-naphthalenyl)-D-alanine]-, acetate (1:x); Luteinizing hormone-releasing factor (pig), 6-[3-(2-naphthalenyl)-D-alanine]-, acetate (salt); Luteinizing hormone-releasing factor (swine), 6-[3-(2-naphthalenyl)-D-alanine]-, acetate (salt); Nafarelin acetate; Synarel; Synarela; H-Pyr-His-Trp-Ser-Tyr-D-2Nal-Leu-Arg-Pro-Gly-NH2.CH3CO2H; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-(2-naphthyl)-D-alanyl-L-leucyl-L-arginyl-L-prolyl-glycinamide acetic acid. Grades: ≥95%. CAS No. 76932-60-0. Molecular formula: C66H83N17O13.xC2H4O2. Mole weight: 1322.47 (free base). | |
| NAI-N3 | NAI-N3 is a novel RNA acylation reagent that enables RNA purification. Synonyms: [2-(azidomethyl)pyridin-3-yl]-imidazol-1-ylmethanone. CAS No. 1612756-29-2. Molecular formula: C10H8N6O. Mole weight: 228.21. | |
| N-Allylmaleimide | N-Allylmaleimide, a compound with biomedical research applications, boasts an inhibitory prowess for the growth of select cancer cells. In addition, studies have revealed its potential neuroprotective attributes, making it a promising candidate for neurodegenerative disease treatment. Surmised to exert its effects via hindrance of protein-protein associations, this agent exhibits dynamic impact on applicable systems. Synonyms: 1-Allyl-1H-pyrrole-2,5-dione. Grades: 98%. CAS No. 2973-17-3. Molecular formula: C7H7NO2. Mole weight: 137.14. | |
| N-Allylthiourea | Cas No. 109-57-9. | |
| Naloxegol oxalate | Naloxegol oxalate is a CYP3A4 enzyme inhibitor, is a peripherally-selective opioid antagonist, for the treatment of opioid-induced constipation. Synonyms: Morphinan-3,14-diol, 4,5-epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propen-1-yl)-, (5α,6α)-, ethanedioate (1:1); AZ 13337019 oxalate; AZ13337019 oxalate; AZ-13337019 oxalate; Moventig; NKTR 118 oxalate; (4R,4aS,7S,7aR,12bS)-7-((2,5,8,11,14,17,20-heptaoxadocosan-22-yl)oxy)-3-allyl-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol oxalate. Grades: >98%. CAS No. 1354744-91-4. Molecular formula: C36H55NO15. Mole weight: 741.82. | |
| N-α-Acetyl-L-aspartic acid | N-α-Acetyl-L-aspartic acid, a naturally occurring compound, is ubiquitous in mammals' nervous and immune systems. Its vital function in regulating brain activity renders it a promising therapeutic agent for various neurological conditions. This includes Alzheimer's and multiple sclerosis. In addition, it's investigated for potential efficacy against chemotherapy and radiation-caused neurotoxicity. Synonyms: Acetyl-L-aspartic Acid; Acetylaspartic Acid; L-N-Acetylaspartic Acid; N-Acetyl-L-aspartic Acid; N-Acetylaspartic Acid; Ac-Asp-OH; (S)-2-Acetamidosuccinic acid; (S)-2-(acetylamino)butanedioic acid. Grades: ≥98%. CAS No. 997-55-7. Molecular formula: C6H9NO5. Mole weight: 175.14. | |
| Nα-Boc-Nω,Nω'-bis-Z-L-arginine | Nα-Boc-Nω,Nω'-bis-Z-L-arginine, a synthetic compound with widespread usage in proteomics research, serves as a competent agent for the blocking of trypsin digestion. Its versatility extends beyond this application and is also harnessed in peptide and protein synthesis procedures. Synonyms: Boc-L-Arg(Z)2-OH; (S)-5-(1,3-Bis((Benzyloxy)Carbonyl)Guanidino)-2-((Tert-Butoxycarbonyl)Amino)Pentanoic Acid. Grades: ≥ 98% (HPLC). CAS No. 51219-19-3. Molecular formula: C27H34N4O8. Mole weight: 542.60. | |
| Nα-Fmoc-Nε-2,4-dinitrophenyl-L-lysine | Synonyms: Fmoc-L-Lys(Dnp)-OH. Grades: ≥ 98% (HPLC). CAS No. 148083-64-1. Molecular formula: C27H26N4O8. Mole weight: 534.53. | |
| Nα,Nα-Bis-Fmoc-L-cystine bis(tert-butyl ester) | Synonyms: (Fmoc-L-Cys-OtBu)2; (2R)-tert-Butyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(((2R)-3-(tert-butoxy)-2-((((1,2,3,3a,8,8a-hexahydrocyclopenta[a]inden-8-yl)methoxy)carbonyl)amino)-3-oxopropyl)disulfanyl)propanoate; tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[[(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]-3-oxopropyl]disulfanyl]propanoate; (Fmoc-Cys-OtBu)2; (Fmoc-cys-otbu)2 (disulfide bond); L-Cystine, N,N'-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1,1'-bis(1,1-dimethylethyl) ester; N,N'-Bis(9H-fluorene-9-ylmethoxycarbonyl)-L-cystine ditert-butyl ester. Grades: ≥ 98% (HPLC). CAS No. 139592-37-3. Molecular formula: C44H48N2O8S2. Mole weight: 796.99. | |
| N-α-(t-Butoxycarbonyl)-O-trityl-L-serine | Utilized extensively in the production of peptides and proteins, N-α-(t-Butoxycarbonyl)-O-trityl-L-serine is a chemical compound boasting diverse applications within the pharmaceutical arena. In addition to its fundamental use in pharmaceutical synthesis, this compound demonstrates further utility as a therapeutic agent in the treatment of cancer and autoimmune disorders. Synonyms: Boc-Ser(Trt)-OH; (S)-2-((tert-Butoxycarbonyl)amino)-3-(trityloxy)propanoic acid. Grades: ≥ 95%. CAS No. 252897-67-9. Molecular formula: C27H29NO5. Mole weight: 447.52. | |
| Namitecan | Namiteca is a new water-soluble camptothecin analogue as a hydrophilic camptothecin with a promising preclinical profile. Uses: Dna topoisomerase i inhibitors. Synonyms: ST-1968; ST 1968; ST1968; Namitecan.(4S)-11-((E)-((2-Aminoethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione. Grades: ≥98%. CAS No. 372105-27-6. Molecular formula: C23H22N4O5. Mole weight: 434.45. | |
| Nanofin | Nanofin is neuropathic blocker used for mild to moderate hypertension. Uses: Neuropathic blocker. Synonyms: 2,6-dimethylpiperidine. Grades: ≥95%. CAS No. 504-03-0. Molecular formula: C7H15N. Mole weight: 113.2. | |
| Nanterinone | Nanterinone is a novel positive inotropic and balanced-type vasodilating drug partially based on phosphodiesterase III inhibition. It exhibits acute hemodynamic effects in patients with mild to moderate heart failure. Uses: Nanterinone is a novel positive inotropic and balanced-type vasodilating drug. Synonyms: UK 61260; UK-61260; UK61260; Nanterinone;6-(2,4-Dimethyl-1h-imidazol-1-yl)-8-methylquinolin-2-ol. Grades: >98 %. CAS No. 102791-47-9. Molecular formula: C15H15N3O. Mole weight: 253.30. | |
| Nanterinone mesylate | Nanterinone mesylate is the methyl sulfonate form of Nanterinone, which is a novel positive inotropic and balanced-type vasodilating drug partially based on phosphodiesterase III inhibition. It exhibits acute hemodynamic effects in patients with mild to moderate heart failure. Uses: Nanterinone mesylate is a novel positive inotropic and balanced-type vasodilating drug. Synonyms: UK 61260; UK-61260; UK61260; Nanterinone mesylate 6-(2,4-Dimethylimidazol-1-yl)-8-methyl-1H-quinolin-2-one methanesulfonic acid;UK-61260;UK61260;6-(2,4-Dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one methanesulfonate. Grades: >98 %. CAS No. 102791-74-2. Molecular formula: C16H19N3O4S. Mole weight: 349.40. | |
| Naphthofluorescein | Naphthofluorescein is a furin inhibitor that inhibits furin-mediated cleavage of the pro-form of membrane type-1 matrix metalloproteinase (MT1-MMP), resulting in decreased levels of active MT1-MMP. Naphthofluorescein is a red-emitting fluorescent probe for hydrogen peroxide in living cells. Synonyms: CCG 8295. Grades: ≥98%. CAS No. 61419-02-1. Molecular formula: C28H16O5. Mole weight: 432.4. | |
| N-Arachidonylglycine | N-Arachidonylglycine has been isolated from cell cultures treated with arachidonoyl ethanolamide. It is a GPR18 agonist with EC50 value of 44.5 nM. It is a kind of endogenous anandamide-like compound. It is also an endogenous GlyT2 inhibitor and acts as a glycine transporter inhibitor. It has also been synthesized as an analog of AEA for structure/activity testing. It may be produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA. It has analgesic activities in whole animal experiments. Synonyms: N-[1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]-glycine; Arachidonyl Glycine; (all-Z)-N-(1-Oxo-5,8,11,14-eicosatetraenyl)glycine; N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraenyl]glycine. Grades: ≥98% by HPLC. CAS No. 179113-91-8. Molecular formula: C22H35NO3. Mole weight: 361.52. | |
| N-Arachidonyl maleimide | N-Arachidonyl maleimide (NAM) is a potent and irreversible inhibitor of monoacylglycerol lipase (MAGL), an enzyme in the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). Synonyms: NAM; 1-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]pyrrole-2,5-dione. Grades: ≥98%. CAS No. 876305-42-9. Molecular formula: C24H35NO2. Mole weight: 369.5. | |
| Narciclasine | Narciclasine, which can be found in the tubers of Narcissus tazetta, displays marked proapoptotic and cytotoxic activity, as does pancratistatin, and significant in vivo anticancer effects in various experimental models. It is a potential agent for the treatment of primary brain cancers and various brain metastases. Uses: Anti-inflammatory. Synonyms: (13β)-1,19-Didehydro-2α,3β,4β,7-tetrahydroxy-11,12-dinor-5,19-secocrinan-6-one; (2S)-3,4,4aβ,5-Tetrahydro-2α,3β,4β,7-tetrahydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one; Lycorcidinol. Grades: ≥95%. CAS No. 29477-83-6. Molecular formula: C14H13NO7. Mole weight: 307.25. | |
| Naringenin chalcone | Naringenin chalcone is a natural chalconoid that can be isolated from tomato skin. It exhibits antioxidant, anti-inflammatory, and anti-allergic properties. Synonyms: Chalconaringenin; Isosalipurpol; trans-2'4'6'4-tetrahydroxychalcone. CAS No. 73692-50-9. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Naringin dihydrochalcone | Naringin Dihydrochalcone (Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway. Uses: Antioxidant/sweetener. Synonyms: 1-[4-[(2-O-(6-Deoxy-a-L-rhamnopyranosyl)-b-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone. Grades: >98%. CAS No. 18916-17-1. Molecular formula: C27H34O14. Mole weight: 582.55. | |
| NAV 2729 | NAV 2729 is an ADP-ribosylation factor 6 (ARF6) inhibitor with IC50 value of 1.0 μM. It can reduce tumorigenesis in mouse model of uveal melanoma. Synonyms: NAV-2729; NAV 2729; NAV2729. 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one. Grades: ≥98% by HPLC. CAS No. 419547-11-8. Molecular formula: C25H17ClN4O3. Mole weight: 456.88. | |
| Navamepent | Navamepent is an inflammation mediator inhibitor and lipid modulator originated by Resolvyx Pharmaceuticals and licensed to Auven Therapeutics in 2011. Treatment for Postoperative inflammation and Postoperative pain are in clinical trials Phase II. Treatment for Age-related macular degeneration and Diabetic macular oedema are in preclinical trials. Uses: Postoperative inflammation; postoperative pain;age-related macular degeneration; diabetic macular oedema. Synonyms: (5S,8E,10E,12R)-5,12-Dihydroxy-8,10-pentadecadiene-6,14-diynoic Acid 1-Methylethyl Ester;RX-10045; RX10045; RX 10045. Grades: 98%. CAS No. 1251537-11-7. Molecular formula: C18H24O4. Mole weight: 304.39. | |
| NB-598 | SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598. Synonyms: NB 598; NB598. Grades: >98%. CAS No. 131060-14-5. Molecular formula: C27H31NOS2. Mole weight: 449.67. | |
| NB-598 hydrochloride | NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). Synonyms: NB 598 hydrochloride; NB598 hydrochloride. Grades: >98%. CAS No. 136719-25-0. Molecular formula: C27H32ClNOS2. Mole weight: 486.13. | |
| NB-598 Maleate | SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598. Synonyms: NB598 Maleate; NB 598 Maleate. Grades: >98%. CAS No. 155294-62-5. Molecular formula: C31H35NO5S2. Mole weight: 565.74. | |
| N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite | N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (CAS# 110782-31-5) is a nucleotide used in the synthesis of native-like crosslinked duplex RNA. Synonyms: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite; Dmt-2'-O-me-ra(bz) amidite; 2'-O-Methyl-rA(N-Bz)phosphoramidite; DMT-2'O-Methyl-rA(bz) Phosphoramidite; 5'-O-DMT-2'-O-Me-A(bz) phosphoramidite. Grades: ≥ 98 %. CAS No. 110782-31-5. Molecular formula: C48H54N7O8P. Mole weight: 887.96. | |
| N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite | N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used to incorporate nucleoside A into the synthesis of oligonucleotides. Synonyms: Bz-rA Phosphoramidite; DMT-2'O-TBDMS-Ra(Bz) Phosphoramidite; (2R, 3R, 4R, 5R) -5- (6-Benzamido-9H-purin-9-yl) -2- ( (bis (4-methoxyphenyl) (phenyl) methoxy) methyl) -4- ( (tert-butyldimethylsilyl) oxy) tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grades: 98%. CAS No. 104992-55-4. Molecular formula: C53H66N7O8PSi. Mole weight: 988.22. | |
| NBMPR | NBMPR is an equilibrative nucleoside transporter (ENT) 1 inhibitor. Uses: Affinity labels. Synonyms: 6-S-[(4-Nitrophenyl)methyl]-6-thioinosine. Grades: ≥99% by HPLC. CAS No. 38048-32-7. Molecular formula: C17H17N5O6S. Mole weight: 419.41. | |
| N-Boc-N-methyl-3-tert-butyl-L-alanine | N-Boc-N-methyl-3-tert-butyl-L-alanine, a synthetically derived amino acid compound, exhibits promise as a therapeutic agent for the treatment of numerous diseases, including cancer and Alzheimer's. Given its potential pharmacological activity, this compound has garnered interest for deployment in drug development. Synonyms: Boc-N(Me)Ala(tBu)-OH; (S)-2-(tert-butoxycarbonyl(methyl)amino)-4,4-dimethylpentanoic acid. CAS No. 287210-82-6. Molecular formula: C13H25NO4. Mole weight: 259.34. | |
| n-Butylidenephthalide | antiarrhythmic. Uses: Antiarrhythmic. Synonyms: 1(3H)-Isobenzofuranone, 3-butylidene-; Phthalide, 3-butylidene-; 3-Butylidene-1(3H)-isobenzofuranone; Butylidenephthalide; 3-Butylidenephthalide; Ligusticum lactone; NSC 325307. Grades: >98% (mixture of cis and trans isomers). CAS No. 551-08-6. Molecular formula: C12H12O2. Mole weight: 188.22. | |
| N-Butyl Scopolamine Bromide (N-Butyl Hyoscine Bromide) | Cas No. 149-64-4. | |
| NC 174 | NC-174 is a trisubstituted guanidine high potency synthetic sweetener. Uses: Sweetener. Synonyms: CP-Dpm-GA; CPDpmGA; CP-DpmGA; CPDpm-GA; CP Dpm GA; NC174; NC 174; NC-174; N- ( ( (4-cyanophenyl)amino) ( (diphenylmethyl)amino)methylene)-Glycine. Grades: 98%. CAS No. 138460-25-0. Molecular formula: C23H22N4O2. Mole weight: 384.44. | |
| N-Carbobenzoxy-β-alaninol | N-Carbobenzoxy-β-alaninol (CAS# 34637-22-4) is a useful research chemical. Synonyms: Z-β-Ala-ol; Z-NH-(CH2)3-OH; 3-(Carbobenzoxyamino)-1-propanol; Benzyl (3-hydroxypropyl)carbamate; Benzyl N-(3-hydroxypropyl)carbamate; 3-(Cbz-amino)-1-propanol. CAS No. 34637-22-4. Molecular formula: C11H15NO3. Mole weight: 209.24. | |
| NCB-0846 | NCB-0846 is an orally available, first-in-class TNIK inhibitor (IC50 = 21?nM) and shows marked anti-tumour and anti-CSC activities. Synonyms: NCB-0846; NCB 0846; NCB0846; 4-[2-(3H-benzimidazol-5-ylamino)quinazolin-8-yl]oxycyclohexan-1-ol. CAS No. 1792999-26-8. Molecular formula: C21H21N5O2. Mole weight: 375.42. | |
| N-(Chloroacetoxy)succinimide | N-(Chloroacetoxy)succinimide is a reagent used in the preparation of organometallic complexes and other synthetic probes for the labeling of proteins. Synonyms: 1-[(chloroacetyl)oxy]pyrrolidine-2,5-dione; 2-chloro-Acetic acid 2,5-dioxo-1-pyrrolidinyl ester. CAS No. 27243-15-8. Molecular formula: C6H6ClNO4. Mole weight: 191.57. | |
| NCL 00017509 | NCL00017509 is a NIMA related kinase 2 inhibitor with IC50 value of 56 nM. It can induce increased mitotic abnormalities and mitotic delay. Synonyms: NCL00017509; NCL 00017509; NCL-00017509; 3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide. Grades: 97%. CAS No. 1507367-00-1. Molecular formula: C15H12N6O. Mole weight: 292.29. | |
| NCRW0005-F05 | NCRW0005-F05 is the first GPR139 antagonist (IC50 = 0.21 μM). Synonyms: NCRW0005-F05; NCRW0005 F05; NCRW0005F05; 3,3-difluoro-4-(4-methoxyphenyl)-1-phenylazetidin-2-one. Grades: 99%. CAS No. 342779-66-2. Molecular formula: C16H13F2NO2. Mole weight: 289.28. | |
| NCS-382 | NCS-382 is a γ-Hydroxybutyric acid antagonist as an anticonvulsant. Uses: Anticonvulsants. Synonyms: NCS-382; NCS 382; NCS382; 6,7,8,9-Tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylideneacetic acid. Grades: ≥99% by HPLC. CAS No. 520505-01-5. Molecular formula: C13H14O3. Mole weight: 218.25. | |
| NCT-501 | NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. Synonyms: NCT501; NCT 501. Grades: 98%. CAS No. 1802088-50-1. Molecular formula: C21H32N6O3. Mole weight: 416.52. | |
| NCT-502 | NCT-502 is an inhibitor of human 3-phosphoglycerate dehydrogenase (PHGDH). It reduces the production of glucose-derived serine in cells and suppresses the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors. Synonyms: NCT 502; NCT502; N-(4,6-Dimethyl-2-pyridinyl)-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarbothioamide. Grades: ≥98%. CAS No. 1542213-00-2. Molecular formula: C18H20F3N5S. Mole weight: 395.4. | |
| N-Cyano-N'-methyl-ethanimidamide | N-Cyano-N'-methyl-ethanimidamide has exhibited significant inhibitory activity against the dipeptidyl peptidase IV (DPP-4), which represents a pharmacological target for mitigating type 2 diabetes. In addition to this, the product has demonstrated antiviral potential against a diverse range of viral strains, among which the human immunodeficiency virus (HIV) is notable. The product's diverse clinical applications thus mandate in-depth investigation and analysis. Synonyms: 1-Cyanoimino-N-methylethanamine. CAS No. 56563-12-3. Molecular formula: C4H7N3. Mole weight: 97.12. | |
| N-Cyclohexanecarbonylpentadecylamine | N-Cyclohexanecarbonylpentadecylamine is a selective inhibitor of acidic palmitoyl ethanolamidase (PEAase) with IC50 value of 4.5 μM. Synonyms: 16-Amino-1-cyclohexylhexadecan-1-one. Grades: ≥98%. CAS No. 702638-84-4. Molecular formula: C22H43NO. Mole weight: 337.6. | |
| N-Cyclohexylsulfamic acid | Cyclamic acid in the form of its sodium or calcium salt is one of the most widely used artificial sweeteners. Uses: Sweetening agents. Synonyms: cyclohexylsulfamic acid. Grades: > 98 %. CAS No. 100-88-9. Molecular formula: C6H13NO3S. Mole weight: 179.24. | |
| N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine | Cas No. 66215-27-8. | |
| N-Cyclopropyl-2-aminotetraline hydrochloride | N-Cyclopropyl-2-Aminotetraline hydrochloride is a MAO inhibitor. Synonyms: N-Cyclopropyl-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride; Cyclopropyl-(1,2,3,4-tetrahydro-naphthalen-2-yl)-amine hydrochloride; Aminotetraline hydrochloride, N-Cyclopropyl-2-. Grades: 98%. CAS No. 1246094-94-9. Molecular formula: C13H17N.HCl. Mole weight: 223.74. | |
| N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide | N-Cyclopropyl-N-methyl-2-Aminotetraline hydrobromide is a MAO inhibitor. Synonyms: Cyclopropyl-methyl-(1,2,3,4-tetrahydro-naphthalen-2-yl)-amine hydrobromide; N-cyclopropyl-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrobromide; Aminotetraline hydrobromide, N-Cyclopropyl-N-methyl-2-. Grades: 99%. CAS No. 1246094-80-3. Molecular formula: C14H19N.HBr. Mole weight: 282.22. | |
| ND-630 | ND-630, also called as NDI 010976, is a highly selective, reversible inhibitor of acetyl-CoA carboxylase (ACC) and had IC50 values of 2 and 7 nM for ACC1 and 2, respectively, EC50 values in HepG2 serum free and 10% serum of 9 and 66 nM, respectively, and 2-fold C2C12 fatty acid oxidation (FAOxn) stimulation at 200 nM. Uses: Enzyme inhibitors. Synonyms: ND 630; ND630; NDI-010976; NDI 010976; NDI010976; GS-0976; GS0976; GS 0976; Firsocostat; Thieno[2,3-d]pyrimidine-3(2H)-acetic acid, 1,4-dihydro-1-[(2R)-2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α,5-trimethyl-6-(2-oxazolyl)-2,4-dioxo-; 1,4-Dihydro-1-[(2R)-2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α,5-trimethyl-6-(2-oxazolyl)-2,4-dioxothieno[2,3-d]pyrimidine-3(2H)-acetic acid; (R)-2-(1-(2-(2-Methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,2-dihydrothieno[2,3-d]pyrimidin-3(4H)-yl)-2-methylpropanoic acid; 2-[1-{(2R)-2-(2-methoxyphenyl)-2-[(oxan-4-yl)oxy]ethyl}-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl]-2-methylpropanoic acid; GS-ACC; GS-Y. Grades: ≥95%. CAS No. 1434635-54-7. Molecular formula: C28H31N3O8S. Mole weight: 569.63. | |
| ND-646 | ND-646 is an orally bioactive inhibitor of acetyl-CoA carboxylase (ACC) that inhibits both ACC1 and ACC2. It prevents ACC subunit dimerization to inhibit fatty acid synthesis in vitro and in vivo. Synonyms: ND 646; ND646; BCP29105; CS-7887; BCP 29105; CS 7887; BCP-29105; CS7887; Thieno[2,3-d]pyrimidine-3(2H)-acetamide, 1,4-dihydro-1-[(2R)-2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α,5-trimethyl-6-(2-oxazolyl)-2,4-dioxo-; 1,4-Dihydro-1-[(2R)-2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α,5-trimethyl-6-(2-oxazolyl)-2,4-dioxothieno[2,3-d]pyrimidine-3(2H)-acetamide; (R)-2-(1-(2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanamide. Grades: ≥95%. CAS No. 1434639-57-2. Molecular formula: C28H32N4O7S. Mole weight: 568.64. | |
| N-deacetylated BMS-202 | The deacetylated of BMS-202 which is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50= 18 nM). Molecular formula: C23H27N3O2. Mole weight: 377.48. | |
| N-Demethyl Olanzapine | N-Demethyl Olanzapine is an impurity of olanzapine, which is a 5-HT2A receptor antagonist used as an antipsychotic medication. Synonyms: 2-methyl-4-(1-piperazinyl)-10H-Thieno[2,3-b][1,5]benzodiazepine; 4'-Desmethylolanzapine; Desmethylolanzapine; LY 170055; N-Demethylolanzapine. CAS No. 161696-76-0. Molecular formula: C16H18N4S. Mole weight: 298.408. | |
| N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride | A metabolite of Quetiapine. Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Synonyms: 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine Dihydrochloride; DBTP; Norquetiapine; Quetiapine EP Impurity B. Grades: > 95%. CAS No. 111974-74-4. Molecular formula: C17H17N3S. 2 HCl. Mole weight: 368.32. | |
| N-Deshydroxyethyl Dasatinib | N-Deshydroxyethyl Dasatinib is a metabolite of Dasatinib. Synonyms: N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolecarboxamide; Dasatinib metabolite M4. Grades: > 95%. CAS No. 910297-51-7. Molecular formula: C20H22ClN7OS. Mole weight: 443.95. | |
| N-Desmethyl Azelastine | N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Synonyms: Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity. Grades: > 95%. CAS No. 47491-38-3. Molecular formula: C21H22ClN3O. Mole weight: 367.88. | |
| N-Desmethyl Enzalutamide | N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors. Uses: The treatment of disorders involving androgen, estrogen and progesterone receptors. Synonyms: N-desmethylenzalutamide; 1242137-16-1; 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzamide; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide; Enzalutamide metabolite. CAS No. 1242137-16-1. Molecular formula: C20H14F4N4O2S. Mole weight: 450.412. | |
| N-Desmethyl Sildenafil-[d8] | Cas No. 1185168-06-2. | |
| N-Despropyl Ropinirole HCl | An impurity of Ropinirole. Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Synonyms: 4-(2-(propylamino)ethyl)indolin-2-one hydrochloride. Grades: > 95%. CAS No. 173990-76-6. Molecular formula: C13H18N2O.HCl. Mole weight: 254.76. | |
| NDMC101 | NDMC101 is a dipeptidyl peptidase-IV (DPPIV) inhibitor. It inhibits transcription factors as NF-κB and NFATc1, demonstrating that it has the potential as a therapeutic agent for inflammation-induced bone diseases. Synonyms: N-(4-chloro-2-fluorophenyl)-2-hydroxybenzamide. CAS No. 1308631-40-4. Molecular formula: C13H9ClFNO2. Mole weight: 265.7. | |
| NDT 9513727 | NDT 9513727 is a C5a receptor (C5aR) antagonist with IC50 value of 11.6 nM. NDT 9513727 can inhibit C5a-induced neutropenia in gerbil and cynomolgus macaque. In the future, NDT 9513727 may be used for the treatment of human inflammatory diseases. Synonyms: NDT9513727; NDT-9513727; NDT 9513727; N,N-Bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-Imidazole-5-methanamine. Grades: ≥98% by HPLC. CAS No. 439571-48-9. Molecular formula: C36H35N3O4. Mole weight: 573.68. | |
| Necrostatin-1 Inactive Control | Necrostatin-1 Inactive Control (Nec-1i) is a cell-permeable demethylated analog of necrostatin-1 (Nec-1), an RIP1 kinase inhibitor. Synonyms: Nec-1i; 5-(Indol-3-ylmethyl)-2-thiohydantoin. Grades: ≥98%. CAS No. 64419-92-7. Molecular formula: C12H11N3OS. Mole weight: 245.3. | |
| Necrostatin 2 | Necrostatin 2 is a potent necroptosis inhibitor. It is a potent in vitro necroptosis inhibitors and is also efficacious in an animal model of ischemic stroke. Synonyms: Necrostatin 2; Necrostatin-2; Necrostatin2; Nec-2; Nec 2; Nec2; 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5R)-. Grades: >98%. CAS No. 852391-19-6. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. | |
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