BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| ML-336 | ML-336 is a quinazolinone-based inhibitor of Venezuelan Equine Encephalitis Virus (VEEV). It inhibits VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and Trinidad donkey). Synonyms: ML 336; ML336; (E)-2-((1,4-dimethylpiperazin-2-ylidene)-amino)-5-nitro-n-phenylbenzamide. Grades: ≥95%. CAS No. 1613465-33-0. Molecular formula: C19H21N5O3. Mole weight: 367.4. |  |
| ML339 | ML339 is a potent and selective CXCR6 antagonist (IC50 = 140 nM) that is selective (IC50 >79 μM) against CXCR5, CXCR4, CCR6 and Apelin receptor (APJ). It has the potential to advance the field of prostate cancer research. Synonyms: N-[(1R,5S)-9-{2-[(2-Chlorophenyl)amino]-2-oxoethyl}-9-azabicyclo[3.3.1]non-3-yl]-3,4,5-trimethoxybenzamide; 9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)-. Grades: ≥95%. CAS No. 2579689-83-9. Molecular formula: C26H32ClN3O5. Mole weight: 502.00. | |
| ML-345 | ML-345 is a small-molecule inhibitor of insulin-degrading enzyme (IDE) that selectively targets Cys819 in IDE. ML-345 is potentially utilized as a pharmacophore for drug development in diabetes and Alzheimer's disease research. Synonyms: ML 345; ML345; 5-Fluoro-2-(2-morpholin-4-yl-5-morpholin-4-ylsulfonylphenyl)-1,2-benzothiazol-3-one. Grades: ≥95%. CAS No. 1632125-79-1. Molecular formula: C21H22FN3O5S2. Mole weight: 479.5. | |
| ML 349 | ML 349 is a lysophospholipase 2 inhibitor with IC50 value of 144 nM. Synonyms: ML349; ML-349; ML 349. (5,5-Dioxido-4H-thieno[3,2-c][1]benzothiopyran-2-yl)[4-(4-methoxyphenyl)-1-piperazinyl]methanone. Grades: ≥98% by HPLC. CAS No. 890819-86-0. Molecular formula: C23H22N2O4S2. Mole weight: 454.56. | |
| ML352 | ML352 is a potent and non-competitive inhibitor of the presynaptic choline transporter (CHT; Ki value 92 nM). Synonyms: ML352; ML-352; ML 352; VU0476201; VU-0476201; VU 0476201; VU0476328; VU-0476328; VU 0476328; N-((3-Isopropylisoxazol-5-yl)methyl)-4-methoxy-3-((1-methylpiperidin-4-yl)oxy)benzamide; 4-methoxy-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide. Grades: 98%. CAS No. 1649450-12-3. Molecular formula: C21H29N3O4. Mole weight: 387.47. | |
| ML 352 hydrochloride | ML 352 hydrochloride is a selective presynaptic choline transporter inhibitor. Synonyms: ML 352 hydrochloride; ML352 hydrochloride; ML-352 hydrochloride; 4-Methoxy-N-[[3-(1-methylethyl)-5-isoxazolyl]methyl]-3-[(1-methyl-4-piperidinyl)oxy]benzamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 1962928-20-6. Molecular formula: C21H29N3O4.HCl. Mole weight: 423.93. | |
| ML 382 | ML 382 is an allosteric modulator of MrgX1 with EC50 value of 190 nM. Synonyms: ML382; ML-382; ML 382; 2-[(Cyclopropylsulfonyl)amino]-N-(2-ethoxyphenyl)benzamide. Grades: ≥98% by HPLC. CAS No. 1646499-97-9. Molecular formula: C18H20N2O4S. Mole weight: 360.43. | |
| ML 385 | ML 385 is a novel and specific inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2; IC50 = 1.9 μM). ML 385 blocks NRF2 transcriptional activity, and enhances the efficacy of carboplatin as well as other chemotherapeutic drugs in lung cancer cells (NSCLC). Synonyms: ML-385; ML 385; ML385; 2-(1,3-benzodioxol-5-yl)-N-[5-methyl-4-[1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl]-1,3-thiazol-2-yl]acetamide. CAS No. 846557-71-9. Molecular formula: C29H25N3O4S. Mole weight: 511.596. | |
| ML390 | ML-390 is an inhibitor of human DHODH, which induces differentiation in acute myeloid leukemia cell lines U937 (murine) and THP-1 (human) cell lines with an EC50 value of approximately 2 μM. Synonyms: ML390; ML 390; ML-390. Grades: 99%. CAS No. 2029049-79-2. Molecular formula: C21H21F3N2O3. Mole weight: 406.4. | |
| MLN4924 HCl | MLN4924 HCl is a potent and selective small molecule NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. Synonyms: MLN4924 HCl; MLN 4924 HCl; MLN-4924 HCl. Grades: >98%. CAS No. 1160295-21-5. Molecular formula: C21H26ClN5O4S. Mole weight: 479.98. | |
| MLR 1023 | Tolimidone is an allosteric Lyn kinase activator with EC50 value of 63 nM. It has been shown to reduce blood glucose levels in mice. Synonyms: Tolimidone; CP 26,154; CP 26,154; CP 26,154; NSC 314335; MLR-1023; MLR 1023; MLR1023. 5-(3-Methylphenoxy)-2(1H)-pyrimidinone. Grades: ≥99% by HPLC. CAS No. 41964-07-2. Molecular formula: C11H10N2O2. Mole weight: 202.21. | |
| MLT-747 | MLT-747 is a potent and selective malt1 peptide cleavage inhibitor. Synonyms: AC-31545; HY-124587; MLT 747; MLT747. Grades: ≥98% by HPLC. CAS No. 2097853-86-4. Molecular formula: C20H21Cl2N7O3. Mole weight: 478.3. | |
| MLT-748 | MLT-748 is a potent and selective malt1 peptide cleavage inhibitor. Synonyms: 1-(5-Chloro-6-(2H-1,2,3-Triazol-2-Yl)Pyridin-3-Yl)-3-(2-Chloro-7-((1R,2R)-1,2-Dimethoxypropyl)Pyrazolo[1,5-A]Pyrimidin-6-Yl)Urea. Grades: ≥98% by HPLC. CAS No. 1832578-30-9. Molecular formula: C19H19Cl2N9O3. Mole weight: 492.3. | |
| MM-22 | MM-22 is a biotinylated anandamide analog. It can block anandamide uptake with IC50 value of 0.5 μM in HaCaT cells. Synonyms: MM-22; MM 22; MM22; (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[2-[2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]ethoxy]ethoxy]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide. Grades: ≥98% by HPLC. CAS No. 956605-71-3. Molecular formula: C36H60N4O5S. Mole weight: 660.95. | |
| m-Methoxytopolin riboside | It can be used in biological study in influence of plant growth regulators on shoot proliferation and secondary metabolite production in micropropagated Huernia hystrix. Synonyms: N6-(m-Methoxybenzyl)adenosine; Mem-TR; 6-(3-Methoxybenzylamino)-9-b-D-ribofuranosylpurine; N6-(3-Methoxybenzyl)adenosine; N-(3-Methoxybenzyl)adenosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methoxybenzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; meta-Methoxytopolin Riboside; N-[(3-Methoxyphenyl)methyl]adenosine. Grades: ≥95%. CAS No. 101565-95-1. Molecular formula: C18H21N5O5. Mole weight: 387.39. | |
| MMV390048 | MMV390048 is a novel antimalarial compound and it can competitively inhibit the binding of only a single protein, P. falciparum PI4 kinase, to the beads. MV390048 can become a child-friendly drug candidate for uncomplicated malaria that could be given as one single dose, completing the treatment in just one day. In May 2016, Phase I/II clinical trials in Malaria (In volunteers) in Australia was on-going. Uses: Malaria. Synonyms: UNII-0Z5T00JJ10;5-(4-(methylsulfonyl)phenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine;MMV390048; MMV-390048; MMV 390048; MMV-048; MMV 048; MMV048. Grades: 98%. CAS No. 1314883-11-8. Molecular formula: C18H14F3N3O2S. Mole weight: 393.38. | |
| MN-64 | MN-64 is a very potent and selective inhibitor of Tankyrase 1 and 2 with IC50 values of 6 and 72 nM, respectively. It blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system. It affects cell proliferation with potential treatment for cancers. It is a flavonoid compound with anti-cancer/ anti-bacterial properties. It was effective Wnt/β- catenin inhibitors at 1 μM, and inhibited STF luciferase activity at 200 nM in the HEK293 cells in vitro. Uses: Mn-64 has anti-cancer/ anti-bacterial properties and is used for the treatment for cancers. Synonyms: MN-64; MN 64; MN64. 2-(4-Isopropylpheny)-4H-chroMen-4-one;2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one;MN64;2-(4-propan-2-ylphenyl)chromen-4-one. Grades: >98%. CAS No. 92831-11-3. Molecular formula: C18H16O2. Mole weight: 264.32. | |
| Mogroside IIA2 | Mogroside IIA2 is extracted from the fruits of Siraitia grosvenorii Swingle. Synonyms: Mogroside II-A2; MOGROSIDE IIA2; 88901-45-5; (2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R)-6-[[(3S,9R,11R,13R,14S)-17-[(2R,5R)-5,6-dihydroxy-6-methylheptan-2-yl]-11-hydroxy-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol; MogrosideIIA2; CHEBI:145192. Grades: >98%. CAS No. 88901-45-5. Molecular formula: C42H72O14. Mole weight: 801.01. | |
| Mogroside III | Mogroside III is extracted from the fruits of Siraitia grosvenorii Swingle. Synonyms: (3beta,9beta,10alpha,11alpha,24R)-3-(beta-D-Glucopyranosyloxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside. Grades: >98%. CAS No. 130567-83-8. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Mogroside IIIA1 | Mogroside IIIA1 is extracted from the fruits of Siraitia grosvenorii Swingle. Synonyms: Mogroside III A1; Mogroside IIIa; 188901-42-2; Mogroside III-A18174AH. Grades: >98%. CAS No. 88901-42-2. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Mogroside IIIe | Mogroside IIIe is an exquisite natural compound hailing from Siraitia grosvenorii, revered for its antioxidant prowess. This divine extract aids in studying ailments of oxidative magnitude. Synonyms: Mogroside III-E; Mogroside IIIe; 88901-37-5; Mogroside e; DTXSID501316889; HY-N6928; AKOS030530146; CS-0027950. Grades: >98%. CAS No. 88901-37-5. Molecular formula: C48H82O19. Mole weight: 963.2. | |
| Mogroside IV | Mogroside IV is extracted from the fruit of Siraitia grosvenorii Swingle. It exhibited maltase inhibitory effect. Synonyms: (1S,4R,9β,11α,24R)-1-{[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy}-11,25-dihydroxy-9,10,14-trimethyl-4,9-cyclo-9,10-secocholest-5-en-24-yl 2-O-β-L-glucopyranosyl-β-D-glucopyranoside; β-D-Glucopyranoside, (1R, 4R)-4-[(3β, 9β, 10α, 11α, 17β)-3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-11-hydroxy-4, 4, 9, 14-tetramethylestr-5-en-17-yl]-1-(1-hydroxy-1-methylethyl)pentyl 2-O-β-L-glucopyranosyl-. Grades: >98%. CAS No. 89590-95-4. Molecular formula: C54H92O24. Mole weight: 1125.29. | |
| Mogroside IVa | Mogroside IVa is extracted from the fruit of Siraitia grosvenorii Swingle. Synonyms: Mogroside IVa; 88901-41-1; 2-(hydroxymethyl)-6-[[3,4,5-trihydroxy-6-[[11-hydroxy-17-[6-hydroxy-6-methyl-5-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyheptan-2-yl]-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-2-yl]methoxy]oxane-3,4,5-triol; SCHEMBL21980470; FT-0775894; B0005-465739. Grades: >98%. CAS No. 88901-41-1. Molecular formula: C54H92O24. Mole weight: 1125.29. | |
| Moguisteine | Moguisteine is a novel peripheral nonnarcotic antitussive agent that has proved to be as active as codeine in several experimental models of induced cough in guinea-pigs and dogs. Synonyms: BBR-2173; BBR2173; BBR 2173. Grades: >98%. CAS No. 119637-67-1. Molecular formula: C16H21NO5S. Mole weight: 339.41. | |
| Monascin | Monascin is a pigment that displays more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: Monascoflavin; 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(3H)?-dione, 3a,?4,?8,?9a-tetrahydro-9a-methyl-3-(1-oxohexyl)?-6-(1E)?-1-propen-1-yl-, (3S,?3aR,?9aR)?-. Grades: >95%. CAS No. 21516-68-7. Molecular formula: C21H26O5. Mole weight: 358.44. | |
| Monnieriside G | Monnieriside G is a chromone glycoside isolated from the fruits of Cnidium monnieri. Synonyms: (2R)-2-[1-(beta-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-4-hydroxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one. Grades: >98%. CAS No. 1401799-34-5. Molecular formula: C21H26O10. Mole weight: 438.43. | |
| Mono(6-ethanediamine-6-deoxy)-beta-cyclodextrin | Mono(6-ethanediamine-6-deoxy)-beta-cyclodextrin is a versatile compound widely used in the biomedical industry. It acts as a molecular carrier aiding in the solubilization and stabilization of various drugs, including anti-cancer agents, antibiotics, and antivirals. Additionally, it exhibits potential therapeutic efficacy against various diseases such as Alzheimer's, HIV/AIDS, and diabetes. Synonyms: Mono(6-ethanediamine-6-deoxy)-b-cyclodextrin; Mono(6-ethanediamine-6-deoxy)-β-cyclodextrin; 6A-[(2-Aminoethyl)amino]-6A-deoxy-beta-Cyclodextrin. Grades: 95% by HNMR. CAS No. 60984-63-6. Molecular formula: C44H76N2O34. Mole weight: 1177.07. | |
| Mono(6-mercapto-6-deoxy)-beta-cyclodextrin | Mono(6-mercapto-6-deoxy)-beta-cyclodextrin, a remarkable biomedicine, plays a pivotal role in addressing an array of ailments. Unveiling unparalleled drug delivery traits, it fuels the enhancement of drug solubility and stability. Embraced widely in the pharmaceutical realm, it powerfully ameliorates drug bioavailability while selectively targeting diverse maladies like cancer, infections, and inflammatory disorders. Synonyms: Mono(6-mercapto-6-deoxy)-β-cyclodextrin. Grades: 98% by HNMR. CAS No. 81644-55-5. Molecular formula: C42H70O34S. Mole weight: 1151.05. | |
| Mono-6-O-(p-toluenesulfonyl)-b-cyclodextrin | Mono-6-O-(p-toluenesulfonyl)-b-cyclodextrin, an indispensable compound in the biomedical sector, exhibits remarkable significance in augmenting the solubility, stability, and bioavailability of pharmaceuticals. Its vital function revolves around the formulation of diverse drugs, specifically those grappling with limited aqueous solubility. It finds extensive utilization within drug delivery systems, consequently fostering enhanced therapeutic effectiveness, thereby efficaciously combatting the targeted ailments. Synonyms: 6-O-(p-Toluenesulfonyl)-bCD. CAS No. 67217-55-4. Molecular formula: C49H76O37S. Mole weight: 1289.17. | |
| Monoacylglycerol Lipase Inhibitor 21 | MAGL inhibitor 21 is a potent and selective inhibitor of monoacylglycerol lipase (MAGL), an enzyme responsible for the inactivation of the endocannabinoid 2-arachidonoylglycerol (2-AG). It exhibits analgesic and tissue-protecting effects in animal models. Synonyms: MAGL Inhibitor 21; 1,3-Benzodioxol-5-ylmethyl 6-(4-phenylphenyl)hexanoate. Grades: ≥98%. CAS No. 1643657-35-5. Molecular formula: C26H26O4. Mole weight: 402.5. | |
| Monochlorotriazinyl-beta-Cyclodextrin | Monochlorotriazinyl-beta-Cyclodextrin, a highly multifaceted biomolecule employed in drug delivery and pharmaceutical compositions, finds extensive usage in augmenting drug solubility and stability. Its broad-spectrum applications extend to the amelioration of various drugs, including antifungal, antihypertensive, and anticancer agents. Its chromatographic methods are useful for protein and enzyme purifications. Owing to its complex nature and the observed variations, Monochlorotriazinyl-beta-Cyclodextrin offers a wealth of opportunities for research and exploration in the field of biochemistry. Synonyms: Monochlortriazingl-β-Cyclodextrin; beta-Cyclodextrin, 6-chloro-1,4-dihydro-4-oxo-1,3,5-triazin-2-yl ether, sodium salt; β-Cyclodextrin, 6-chloro-1,4-dihydro-4-oxo-1,3,5-triazin-2-yl ether, sodium salt. Grades: 95%. CAS No. 187820-08-2. | |
| Monodes(N-carboxymethyl)valine Daclatasvir | Monodes(N-carboxymethyl)valine Daclatasvir is an impurity of Daclatasvir, a medication that is effective against hepatitis C virus (HCV). Synonyms: N- [ (1S) -2-Methyl-1- [ [ (2S) -2- [5- [4'- [2- [ (2S) -2-pyrrolidinyl] -1H-imidazol-5-yl] [1, 1'-biphenyl] -4-yl] -1H-imidazol-2-yl] -1-pyrrolidinyl] carbonyl] propyl] carbamic Acid Methyl Ester. Grades: ≥98% (HPLC). CAS No. 1007884-60-7. Molecular formula: C33H39N7O3. Mole weight: 581.71. | |
| Monostearyl Maleate | Synonyms: Monostearyl Fumarate; (Z)-4-octadecoxy-4-oxobut-2-enoic acid. CAS No. 2424-62-6. Molecular formula: C22H40O4. Mole weight: 368.558. | |
| Montelukast Sodium Salt | Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: MK-0476; MK 0476; MK0476. Grades: >98%. CAS No. 151767-02-1. Molecular formula: C35H36ClNO3S.Na. Mole weight: 608.17. | |
| Morin | Morin induces caspase-dependent apoptosis through extrinsic pathway by upregulating Fas receptor as well as through the intrinsic pathway by modulating Bcl-2 and IAP family members. Uses: Anti-cancer. Synonyms: TIMTEC-BB SBB008853; MORIN; 3,5,7,2',4'-PENTAHYDROXYFLAVONE; 2',3,4',5,7-PENTAHYDROXYFLAVONE; FUSTIC; CI 75660; CI NO 75660; 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on. Grades: >98%. CAS No. 480-16-0. Molecular formula: C15H10O7. Mole weight: 302.24. | |
| Morin hydrate | Morin is a natural compound isolated from Maclura pomifera (Osage orange). Morin induces caspase-dependent apoptosis through extrinsic pathway by upregulating Fas receptor as well as through the intrinsic pathway by modulating Bcl-2 and IAP family members. Uses: Anti-cancer. Synonyms: 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-, hydrate (1:x); 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one hydrate (1:x); 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-, hydrate; Flavone, 2',3,4',5,7-pentahydroxy-, hydrate; 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one hydrate. Grades: >98%. CAS No. 654055-01-3. Molecular formula: C15H10O7.xH2O. Mole weight: 302.24 (anhydrous basis). | |
| Motexafin Lutetium Hydrate | The hydrate form of Motexafin Lutetium that has been found to probably be effective in antineoplastic antiatheroscleroticand studies. Uses: Synthetic metal-coordinating expanded porphyrin. diamagnetic photosensitizer that is activated using far-red light to generate cytotoxic singlet oxygen. antiatherosclerotic, antineoplastic (photosensitizer). used in treatment of age-related macular degene. Synonyms: PCI-0123; PCI 0123; PCI0123; Lutetium texaphyrin; NSC-695239; 156436-90-7; Lu tex; NSC695239; Bis(acetato-O)[9,21-bis[2-[2-(2-methoxyethoxy) ethoxy]ethoxy]-4,15-dimethyl-8,11-imino-6,3:13,16-dinitrilo -1,18-benzodiazacycloeicosine-5,14-dipropanolato-N1,N18,N23,N24,N25]Lutetium hydrat. Grades: 98%. CAS No. 156436-90-7. Molecular formula: C52H72LuN5O14.xH2O. Mole weight: 1166.12. | |
| Moxifloxacine hydrochloride | Cas No. 186826-86-8. | |
| Moxifloxacin impurity 001 | An impurity of Moxifloxacin, which is fourth generation antibacterial agent. Molecular formula: C24H31BFN3O4. Mole weight: 455.33. | |
| Moxifloxacin Impurity 18 | An impurity of Moxifloxacin, which is fourth generation antibacterial agent. Synonyms: 7-Amino-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid. Grades: > 95%. CAS No. 172426-88-9. Molecular formula: C14H13N2O4. Mole weight: 292.27. | |
| Moxifloxacin Impurity 30 | An impurity of Moxifloxacin, which is a fourth generation antibacterial agent. Synonyms: 7-(3-(2-carboxyethy)-4-(hydroxyamino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 7-[3-(2-Carboxyethyl)-4-(hydroxyamino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid; 3-Quinolinecarboxylic acid, 7-[3-(2-carboxyethyl)-4-(hydroxyamino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-. CAS No. 1395056-42-4. Molecular formula: C21H24FN3O7. Mole weight: 449.43. | |
| Moxifloxacin Impurity B | Cas No. 1029364-73-5. | |
| Moxifloxacin Impurity D | Cas No. 1029364-77-9. | |
| Moxifloxacin Impurity E | An impurity of Moxifloxacin, which is a fourth generation antibacterial agent. Synonyms: 8-Hydroxy Moxifloxacin; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-hydroxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid. Grades: > 95%. CAS No. 1292904-74-5. Molecular formula: C20H22FN3O4. Mole weight: 387.41. | |
| Moxifloxacin Related Compound A (HCl salt form) | An impurity of Moxifloxacin. Moxifloxacin is an antibiotic used to treat bacterial infenctions such as community acquired pneumonia, complicated skin infections and complicated intra-abdominal infections. Grades: 95%. CAS No. 151282-23-4. Molecular formula: C20H22ClF2N3O3. Mole weight: 425.863. | |
| Moxifloxacin RR-Isomer (HCl salt form) | Cas No. 1394029-14-1. | |
| MOZ-IN-3 | MOZ-IN-3 is a highly potent and selective inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ) with IC50 value of 8 nM. It also inhibits KAT6B/MORF with IC50 value of 28 nM. MOZ-IN-3 induced cell cycle arrest in and inhibited proliferation of mouse embryonic fibroblasts (IC50 = 2.4 μM), and induced cellular senescence without causing DNA damage or displaying a general cytotoxicity effect in mouse lymphoma cells. Synonyms: WM-8014; WM 8014; WM8014; 4-fluoro-5-methyl-N'-(phenylsulfonyl)[1,1'-biphenyl]-3-carbohydrazide. Grades: ≥98%. CAS No. 2055397-18-5. Molecular formula: C20H17FN2O3S. Mole weight: 384.43. | |
| MP-A08 | MP-A08 is a cell permeable selective inhibitor of sphingosine kinase 2 (Ki=6.9 μM) and 1 (Ki=27 μM) with little affinity for other kinases. In vitro: inhibits cellular S1P production and increases sphingosine and ceramide levels. Synonyms: MP-A08; MP A08; MPA08; NSC-122314; NSC 122314; NSC122314; 4- methyl -N- [2- [ [2- [ (4-methyl phenyl ) sulfonyl amino] ph enyl ] imino methyl ] phenyl ] Ben zene sulfonamide MP-A08NSC122314AC1L9JETAmbcb5562335SCHE MBL17443540MCULE-6662772127N- [2- [ [2-(Tosyl amino) benzyl ide ne ] amino ] phenyl ]-4- methyl Benzene sulfonamide MP A08|NSC 1223. CAS No. 219832-49-2. Molecular formula: C27H25N3O4S2. Mole weight: 519.64. | |
| mPEG2000C-DMG | Synonyms: α - (3'-{[1, 2-di (myristyloxy) propanoxy]carbonylamino}propyl) -ω -methoxy, polyoxyethylene. Grades: >97%. CAS No. 1019000-64-6. Molecular formula: (C2H4O)nC36H73NO5. | |
| Mps1-IN-1 | Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM; >1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk. Synonyms: Mps1-IN-1; 1125593-20-5; 1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrrolo[2,3-b]pyridin-6-ylamino)-3-methoxyphenyl)piperidin-4-ol; 1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]piperidin-4-ol; 1MPS1-IN-1; 3gfw; 1-(4-((4-((2-(isopropylsulfonyl)phenyl)amino)-1H-pyrrolo[2,3-b]pyridin-6-yl)amino)-3-methoxyphenyl)piperidin-4-ol; MLS003230944; GTPL9271; SCHEMBL4051419; CHEMBL1235786; BDBM36485; CHEBI:91379; DTXSID60649015; AVB59320; BCP27688; AKOS027422816; CS-3776; NCGC00387463-01; NCGC00387463-04; HY-13298; MS-29898; SMR001913509; F85109; A925638; J-503190; Q27087728; 1-(3-methoxy-4-{[4-({2-[(1-methylethyl)sulfonyl]phenyl}amino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino}phenyl)piperidin-4-ol; 1-[3-Methoxy-4-({4-[2-(propane-2-sulfonyl)anilino]-1H-pyrrolo[2,3-b]pyridin-6-yl}amino)phenyl]piperidin-4-ol; s22. Grades: >98%. CAS No. 1125593-20-5. Molecular formula: C28H33N5O4S. Mole weight: 535.66. | |
| Mps1-IN-1 dihydrochloride | Mps1-IN-1 is a selective inhibitor of monopolar spindle 1 (Mps1) kinase (IC50 = 367 nM), which displays >1000 fold-selectivity against a panel of 352 kinases with the exceptions of ALK and Ltk. Synonyms: 1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1883548-93-3. Molecular formula: C28H35Cl2N5O4S. Mole weight: 608.58. | |
| Mps1-IN-2 | Small-molecule inhibitor of Mps1 kinase (IC50 values 145 nM) with greater than 1000-fold selectivity relative to the 352-member kinase panel, with the major exceptions of Gak and Plk1 (Ambit essay Kd values 12 nM, 140 nM, and 61 nM for Mps1, Gak, and Plk1, respectively). Mps1-IN-2 induces bypass of a checkpoint-mediated mitotic arrest and provides a unique tool to investigate the combined inhibition of Plk1 and Mps1. Synonyms: Mps1-IN-2. Grades: >98%. CAS No. 1228817-38-6. Molecular formula: C26H36N6O3. Mole weight: 480.6. | |
| Mps1-IN-3 | MPS1-IN-3 is a selective and potent MPS1 inhibitor with phenotypic consequences similar to those reported for published MPS1 inhibitors such as MPS1-IN-1, MPS1-IN-2, and AZD3146. Treatment with MPS1-IN-3 at 5 μM sensitized all glioblastoma cells to 3 nM of vincristine as measured by cell counts 11 days posttreatment. U251-FM cells were stereotactically injected into the brain of nude mice. Ten days postinjection, 2 mg/kg of MPS1-IN-3 and/or 0.5 mg/kg of vincristine were administered concomitantly by intravenous injections twice per week for 3 weeks. Synonyms: Mps1-IN-3; Mps1 IN3; Mps1-IN3. Grades: >98%. CAS No. 1609584-72-6. Molecular formula: C26H31N7O4S. Mole weight: 537.63. | |
| Mps1-IN-5 | Mps1-IN-5, also called as BAY1161909, a derivative of triazolopyridine, is an inhibitor of Mps1 kinase (IC50< 10 nmol/L) and in combination with antimitotic cancer drugs it can enhance their efficacy and potentially overcome resistance. Synonyms: BAY1161909; BAY-1161909; BAY 1161909; Empesertib, Mps1-IN-5; (2R)-2-(4-fluorophenyl)-N-[4-[2-(2-methoxy-4-methylsulfonylanilino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]phenyl]propanamideMps1-IN-5SCHEMBL15036597. CAS No. 1443763-60-7. Molecular formula: C29H26FN5O4S. Mole weight: 559.61. | |
| MPS1/TTK Inhibitor | MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK), a dual-specificity kinase playing an essential role in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. Synonyms: N-(2,6-diethylphenyl)-4,5-dihydro-8-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-1-methyl-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide. Grades: ≥98%. CAS No. 1202055-39-7. Molecular formula: C33H40N8O2. Mole weight: 580.72. | |
| Mps BAY 2a | Mps BAY 2a is a potent and selective Mps1 inhibitor (IC50 = 1 nM for human enzyme), which is selective for Mps1 over a panel of 220 kinases. It exhibits anticancer activity in human cancer cells, preparation of combination containing imidazopyridazine derivative useful for the treatment of cancer. Synonyms: N-Cyclopropyl-4-[8-[(2-methylpropyl)amino]-6-(5-quinolinyl)imidazo[1,2-a]pyrazin-3-yl]benzamide; MpsBAY2a; Mps-BAY-2a; Mps BAY 2a. Grades: ≥98% by HPLC. CAS No. 1382477-96-4. Molecular formula: C29H28N6O. Mole weight: 476.57. | |
| MPTP hydrochloride | A dopaminergic neurotoxin that causes permanent symptoms of Parkinson's disease by killing certain neurons in the substantia nigra of the brain. Useful tool compound for Parkinson's disease related studies. Synonyms: MPTP. Grades: >98%. CAS No. 23007-85-4. Molecular formula: C12H16ClN. Mole weight: 209.72. | |
| MreB Perturbing Compound A22 | MreB perturbing compound A22 is a benzylisothiourea compound that rapidly and reversibly perturbs MreB. It converts normal bacterial rod-shape cells to coccoid cells. It interferes with chromosome segregation in C. crescentus by blocking the binding of MreB to chromosomes. Synonyms: 2-(3,4-Dichloro-benzyl)-isothiourea hydrochloride; S-(3,4-Dichlorobenzyl)isothiourea HCl; 3,4-dichlorobenzyl carbamimidothioate hydrochloride. Grades: ≥95%. CAS No. 22816-60-0. Molecular formula: C8H8Cl2N2S·HCl. Mole weight: 271.6. | |
| MRT 67307 dihydrochloride | MRT 67307 is a salt inducible kinase (SIK) inhibitor (IC50 values are 67, 250 and 430 nM for SIK2, SIK1 and SIK3 respectively). MRT67307 potently inhibits ULK1 and ULK2 in vitro and block autophagy in cells. ULK1 inhibition results in accumulation of stalled early autophagosomal structures, indicating a role for ULK1 in the maturation of autophagosomes as well as initiation. Synonyms: MRT 67307 dihydrochloride; MRT67307 dihydrochloride; MRT-67307 dihydrochloride; N- [3- [ [5-Cyclopropyl-2- [ [3- (4-morpholinylmethyl) phenyl] amino] -4-pyrimidinyl] amino] propyl] cyclobutanecarboxamide dihydrochloride. Grades: ≥98% by HPLC. Molecular formula: C26H36N6O2.2HCl. Mole weight: 537.52. | |
| MRT 68601 hydrochloride | MRT 68601 hydrochloride is a potent TBK1 (TANK-binding kinase-1) inhibitor (IC50 = 6 nM). Synonyms: N- [3- [ [5-Cyclopropyl-2- [ [4- (4-morpholinyl) phenyl] amino] -4-pyrimidinyl] amino] propyl] cyclobutanecarboxamide hydrochloride; MRT-68601 HCl; MRT 68601 HCl; MRT68601 HCl. Grades: ≥98% by HPLC. Molecular formula: C25H34N6O2.HCl. Mole weight: 487.04. | |
| MRT-92 | MRT-92 is a potent and selective Smoothened (Smo) receptor inhibitor. MRT-92 displays subnanomolar antagonist activity against Smo in various Hh cell-based assays. MRT-92 inhibits rodent cerebellar granule cell proliferation induced by Hh pathway activation through pharmacologic (half maximal inhibitory concentration [IC50] = 0.4 nM) or genetic manipulation. Synonyms: MRT-92; MRT 92; MRT92. CAS No. 1428315-82-5. Molecular formula: C33H34N4O5. Mole weight: 566.657. | |
| MRTX1257 | MRTX1257 is a KRAS G12C inhibitor. MRTX1257 inhibits KRAS-dependent ERK phosphorylation in the H358 cell assay with IC50 of 900 pM. Synonyms: MRTX-1257; 2206736-04-9; MRTX1257; CHEMBL4632935; 2-[(2S)-4-[7-(8-methylnaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-prop-2-enoylpiperazin-2-yl]acetonitrile. CAS No. 2206736-04-9. Molecular formula: C33H39N7O2. Mole weight: 565.7. | |
| MRTX849 | MRTX849 is a potent and mutation-selective covalent inhibitor of KRAS G12C. It maximizes inhibition by irreversibly locking the KRAS molecule in its inactive state, thereby preventing tumor cell growth which results in tumor cell death. Uses: Antineoplastic agents. Synonyms: MRTX-849; MRTX 849; Adagrasib; 2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile. CAS No. 2326521-71-3. Molecular formula: C32H35ClFN7O2. Mole weight: 604.12. | |
| MS 023 dihydrochloride | MS 023 is a potent and selective type I PRMT inhibitor (IC50= 8, 8, 30, 83 and 119 nM for PRMT6, PRMT8, PRMT1, PRMT4 and PRMT3, respectively). Importantly, MS023 does not inhibit any type II PRMTs (PRMT5 and 9) and type III PRMT (PRMT7) at concentrations up to 10 μM. MS023 displays high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but is completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. Synonyms: MS 023 dihydrochloride; MS023 dihydrochloride; MS-023 dihydrochloride; N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride. Grades: ≥98% by HPLC. Molecular formula: C17H25N3O.2HCl. Mole weight: 360.32. | |
| MS023 hydrochloride | Cas No. 2108631-19-0. | |
| MS049 | MS049 is a potent and selective PRMT4 and PRMT6 inhibitor. MS049 has been shown to reduce the H3R2me2a mark in HEK293 cells with an IC50 value of 0.97 μM and also, unexpectedly, to reduce H4R3me2a in HEK293 cells. Synonyms: MS-049; MS 049; N-Methyl-2-(4-phenylmethoxypiperidin-1-yl)ethanamine. CAS No. 1502816-23-0. Molecular formula: C15H24N2O. Mole weight: 248.36. | |
| MS049 hydrochloride | MS049 is a potent and selective PRMT4 and PRMT6 inhibitor. MS049 has been shown to reduce the H3R2me2a mark in HEK293 cells with an IC50 value of 0.97 μM and also, unexpectedly, to reduce H4R3me2a in HEK293 cells. Synonyms: MS049 HCl; MS049 Dihydrochloride; MS-049 hydrochloride; MS 049 hydrochloride; N-methyl-2-(4-phenylmethoxypiperidin-1-yl)ethanamine dihydrochloride. Grades: ≥98%. CAS No. 2095432-59-8. Molecular formula: C15H24N2O·2HCl. Mole weight: 321.3. | |
| MS049 oxalate salt | MS049 oxalate salt is a potent and selective PRMT4 and PRMT6 inhibitor. MS049 has been shown to reduce the H3R2me2a mark in HEK293 cells with an IC50 value of 0.97 μM and also, unexpectedly, to reduce H4R3me2a in HEK293 cells. Synonyms: MS049 oxalate salt; MS 049 oxalate salt; MS-049 oxalate salt; N-Methyl-4-(phenylmethoxy)-1-piperidineethanamine oxalate salt. Grades: ≥98% by HPLC. Molecular formula: C15H24N2O.C2H2O4. Mole weight: 338.4. | |
| MS 15203 | MS 15203 is a potent and selective GPR171 partial agonist (EC50 = 90 nM; 28% inhibition of forskolin activated adenylyl cyclase activity in rat hypothalamic memebranes). It has also been shown to increases neuronal activity in the paraventricular nucleus, and to ncrease food intake and body weight in mice. Synonyms: MS0015203; MS-0015203; MS 0015203; 5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1,3-benzenedicarboxylic acid. Grades: ≥98% by HPLC. CAS No. 73912-52-4. Molecular formula: C12H11NO5. Mole weight: 249.22. | |
| MS 21570 | MS 21570, a GPR171 antagonist (IC50 = 220 nM), inhibits BigLEN mediated increases in [35S]GTPγS binding in hypothalamic membranes and hyperpolarization of basolateral amygdala pyramidal neurons. Synonyms: N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine; MS21570; MS-21570; MS 21570. Grades: ≥98% by HPLC. CAS No. 65373-29-7. Molecular formula: C10H11N3S2. Mole weight: 237.34. | |
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