BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| LY 163252 | LY 163252 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 163252; LY 163252; LY 163252. 2-(2-methoxy-4-(methylsulfonyl)phenyl)-1H-Imidazo(4,5-c)pyridine monohydrochloride. Grades: 98%. CAS No. 87359-44-2. Molecular formula: C14H14ClN3O3S. Mole weight: 339.80. |  |
| LY 164929 | This active molecular is a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site. Synonyms: LY 164929; LY164929; LY-164929. (S)-N-((R)-1-(2-(((S)-1-(dimethylamino)-3-phenylpropan-2-yl)(ethyl)amino)acetamido)-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)-2-(methylamino)propanamide. Grades: 98%. CAS No. 113573-18-5. Molecular formula: C28H41N5O4. Mole weight: 511.66. | |
| LY 181984 | LY 181984 is an antitumor sulfonylurea. Uses: Antitumor. Synonyms: LY 181984; LY-181984; LY181984; MPCU. N-(((4-chlorophenyl)amino)carbonyl)-4-methyl-Benzenesulfonamide;1-(4-chlorophenyl)-3-(4-methylphenyl)sulfonylurea. Grades: ≥98%. CAS No. 3955-50-8. Molecular formula: C14H13ClN2O3S. Mole weight: 324.78. | |
| LY-183648 | LY-183648 has antiestrogenic activity. It inhibited PAIII metastasis to the gluteal and iliac lymph nodes. Uses: Ly-183648 has antiestrogenic activity. Synonyms: LY 183648; LY183648; LY-183648. 5-[Bis(4-chlorophenyl)-imidazol-1-ylmethyl]pyrimidine; LY183648; Pyrimidine, 5-(bis(4-chlorophenyl)-1H-imidazol-1-ylmethyl)-. Grades: >98 %. CAS No. 102993-90-8. Molecular formula: C20H14Cl2N4. Mole weight: 381.26. | |
| LY-186126 | LY 186126 is a potent cGI-PDE inhibitor. It exhibit reversible and high affinity binding to a single class of SaR binding sites. Synonyms: LY 186126; LY186126; LY-186126. 1,3-Dihydro-1,3,3-trimethyl-5-[(1,4,5,6-tetrahydro-4-methyl-6-oxopyridazin)-3-yl]-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-1,3,3-trimethyl-5-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)-;1,3,3-Trimethyl-6-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)indol-2-one. Grades: >98 %. CAS No. 100644-00-6. Molecular formula: C16H19N3O2. Mole weight: 285.34. | |
| LY 186564 | LY 186564 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 186564; LY186564; LY-186564. 3-(((dipropylamino)carbonyl)oxy)- Estra-1,3,5(10)-trein-17-one. Grades: 98%. CAS No. 143982-31-4. Molecular formula: C25H35NO3. Mole weight: 397.55. | |
| LY 189332 | LY 189332 is a bio-active molecular under the development of Eli Lilly as an antimetastatic drug. Uses: Antimetastatic drug. Synonyms: LY 189332; LY-189332; LY189332. N-(4-fluorophenyl)-4,4''-dimethoxy-(1,1':2',1''-Terphenyl)-4'-amine. Grades: 98%. CAS No. 123215-05-4. Molecular formula: C26H22FNO2. Mole weight: 399.46. | |
| LY 193239 | This bio-active molecular is a cell wall inhibitor as a antibacterial agent. LY 193239 has a lactam pyrazolidinone structure. Clinical trials for Bacterial infections were discontinued. Uses: Antibacterial. Synonyms: LY 193239; LY193239; LY-193239. (2S)-2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-methylsulfonyl-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 124986-46-5. Molecular formula: C14H16N6O7S2. Mole weight: 444.44. | |
| LY-195448 | LY-195448 is a phenethanolamine. It blocks cells at metaphase. It has shown anti-tumour activity. Uses: Ly-195448 has shown anti-tumour activity. Synonyms: LY 195448; LY195448; LY-195448; UNII-BR0DFE3GF6. (R)-4-(3-((2-Hydroxy-2-phenethyl)amino)-3-methylbutyl)benzamide monohydrochloride;4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]benzamide hydrochloride. Grades: >98%. CAS No. 111112-18-6. Molecular formula: C20H27ClN2O2. Mole weight: 362.90. | |
| LY-201409 | LY-201409 is a potent benzamide anticonvulsant. It antagonized maximal electroshock (MES)-induced seizures with ED50 values of 16.2 and 4.2 mg/kg after oral administration to mice and rats, respectively. Uses: Ly-201409 has anticonvulsant effect. Synonyms: LY 201409; LY201409; LY-201409. 4-Amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide;Benzamide, 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethyl-. Grades: >98%. CAS No. 109306-94-7. Molecular formula: C17H20N2O. Mole weight: 268.36. | |
| LY-207702 | LY-207702 is a difluorinated purine nucleoside. It exhibits antitumor activity in preclinical models. It was developed by Eli Lilly & Co. Uses: Ly-207702 exhibits antitumor activity. Synonyms: LY 207702; LY-207702; LY207702. 2',2'-Difluorodeoxyribofuranosyl-2,6-diaminopurine;5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol;9-(2-Deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-9H-purine-2,6-diamine;(2R,3R)-5-(2,6-diamino-7H-purin-8-yl)-4,4-difluoro-2-(hydroxymethyl)oxolan-3-ol;9H-Purine-2,6-diamine, 9-(2-deoxy-2,2-difluoro-D-erythro-pentofuranosyl)-. Grades: >98 %. CAS No. 103828-81-5. Molecular formula: C10H12F2N6O3. Mole weight: 302.24. | |
| LY2109761 | LY2109761 is a novel inhibitor of TGF-β receptor type I/type II kinases (IC50 = 69 nM), displaying antitumor activity. In vivo study demonstrated that LY2109761, in combination with gemcitabine, significantly reduced the tumor burden, prolonged survival, and reduced spontaneous abdominal metastases. Synonyms: LY-2109761; 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine. Grades: >98%. CAS No. 700874-71-1. Molecular formula: C26H27N5O2. Mole weight: 441.52. | |
| LY2183240 2'-isomer | LY2183240 2'-isomer is a 2,5-regioisomer of LY2183240 that inhibits anandamide hydrolysis and cellular reuptake. LY2183240 2'-isomer exhibits less potent activity than LY2183240. Synonyms: 5-([1,1'-Biphenyl]-4-ylmethyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide; 5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide. Grades: ≥98%. CAS No. 1010096-65-7. Molecular formula: C17H17N5O. Mole weight: 307.4. | |
| LY2228820 dimesylate | LY2228820 dimesylate is the salt form of LY2228820, a tri-substituted imidazole derivative and p38α and β MAPK inhibitor. LY2228820 inhibits tumor growth in various cancer models. Synonyms: Ralimetinib Mesylate; Ralimetinib dimesylate; 5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine mesylate. Grades: >98%. CAS No. 862507-23-1. Molecular formula: C26H37FN6O6S2. Mole weight: 612.74. | |
| LY-223592 | LY-223592 is a bio-active chemical compound. It has antitumor activity. It was developed by Eli Lilly & Co. Uses: Ly-223592 has antitumor activity. Synonyms: LY 223592; LY223592; LY-223592. 2'-Deoxy-2',2'-difluoro-guanosine;Guanosine, 2'-deoxy-2',2'-difluoro-;2-Amino-9-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;LY223592;2',2'-Difluorodeoxyguanosine. Grades: >98 %. CAS No. 103828-82-6. Molecular formula: C10H11F2N5O4. Mole weight: 303.22. | |
| LY 231617 | LY 231617 is an antioxidant. It can prevent ischaemia-induced neurodegeneration. LY 231617 is an anti-ischaemic and neuroprotective agent. Synonyms: LY 231617; LY231617; LY-231617; 2,6-bis(1,1-Dimethylethyl)-4-[(ethylamino)methyl]phenol hydrochloride. Grades: ≥98% by HPLC. CAS No. 141545-89-3. Molecular formula: C17H29NO.HCl. Mole weight: 299.88. | |
| LY 243670 | LY 243670 is a bio-active molecular, but detailed information were not published yet. Synonyms: LY 243670; LY-243670; LY243670. 1-(3-Hydroxy-3-cyclohexylpropyl)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidine. Grades: 98%. CAS No. 120938-72-9. Molecular formula: C22-H35-N-O2. Mole weight: 345.52. | |
| LY-2456302 | LY-2456302, also called as CERC-501, is a potent, highly selective and centrally-penetrant kappa opioid receptor antagonist (Ki = 0.807 nM) with favorable pharmacokinetic and pharmacodynamic properties to evaluate the role of KOR in preclinical models of alcoholism. Synonyms: 4-[4-[[(2S)-2-(3,5-dimethylphenyl)pyrrolidin-1-yl]methyl]phenoxy]-3-fluorobenzamide; 3-fluoro4-(4-((2-(3,5-dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide; LY2456302; CERC-501; LY 2456302; CERC 501; LY-2456302; CERC501. CAS No. 1174130-61-0. Molecular formula: C26H27FN2O2. Mole weight: 418.5. | |
| LY 249933 | LY 249933 is a bio-active molecular under the development of Eli Lilly. It has positive inotropic activity as a cardioselective 1,4-dihydropyridine compound. Uses: Positive inotropic activity. Synonyms: LY 249933; LY249933; LY-249933. 1-phenylethyl 2,6-dimethyl-5-nitro-4-thieno[3,2-c]pyridin-3-yl-1,4-dihydropyridine-3-carboxylate. Grades: 98%. CAS No. 123250-77-1. Molecular formula: C23H21N3O4S. Mole weight: 435.50. | |
| LY-2510924 | LY-2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4). It has potential antineoplastic activity. It binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation upon subcutaneous administration, which may result in decreased tumor cell proliferation and migration. It plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types. Uses: Ly-2510924 has potential antineoplastic activity. it plays an important role in chemotaxis and angiogenesis. Synonyms: LY2510924; LY 2510924; Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2; Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2; L-Lysinamide, L-phenylalanyl-L-tyrosyl-N6-(1-methylethyl)-L-lysyl-D-arginyl-3-(2-naphthalenyl)-L-alanylglycyl-D-α-glutamyl-N6-(1-methylethyl)-, (7?1)-lactam; N(1)Phe-Tyr-Lys(iPr)-D-Arg-2Nal-Gly-D-Glu(1)-Lys(iPr)-NH2. Grades: 98%. CAS No. 1088715-84-7. Molecular formula: C62H88N14O10. Mole weight: 1189.47. | |
| LY 255262 | This bio-active molecular is a antibacterial agent with a pyrazolidinone structure. Uses: Antibacterial. Synonyms: LY 255262; LY255262; LY-255262. 2-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-6-cyano-3-oxo-2,7-dihydro-1H-pyrazolo[1,2-a]pyrazole-5-carboxylic acid. Grades: 98%. CAS No. 124986-45-4. Molecular formula: C14H13N7O5S. Mole weight: 391.36. | |
| LY2584702 | LY2584702 is an orally available inhibitor of p70S6K signaling, with potential antineoplastic activity. Synonyms: LY-2584702; LY 2584702. CAS No. 1082949-67-4. Molecular formula: C21H19F4N7. Mole weight: 445.4256. | |
| LY-2584702 hydrochloride | The hydrochloride salt form of LY2584702 which is a selective ATP competitive inhibitor of p70 S6 kinase. LY2584702 is still under Phase I trial for evaluating its potential anti-tumor effect.IC50: 4 nM (LY2584702). Uses: The hydrochloride salt form of ly2584702 which is a selective atp competitive inhibitor of p70 s6 kinase. Synonyms: LY-2584702 (hydrochloride); LY 2584702 (hydrochloride); LY2584702 (hydrochloride); SCHEMBL312564; CS-3598; CS 3598; CS3598. Grades: 98%. CAS No. 1082948-81-9. Molecular formula: C21H20ClF4N7. Mole weight: 481.88. | |
| LY2584702 Tosylate | LY2584702 Tosylate is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1. Synonyms: 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate; LY2584702; LY 2584702; LY-2584702; LYS6K2. Grades: >98%. CAS No. 1082949-68-5. Molecular formula: C28H27F4N7O3S. Mole weight: 617.62. | |
| LY2784544 | LY2784544 is a potent and selective JAK2 inhibitor (IC50 = 3 nM), and exhibits less potency against JAK3 (IC50 =48 nM). LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC50 = 20 and 55 nM, respectively). It reduces JAK2V617F tumor cell burden with no effect on erythroid progenitor cells. Synonyms: Gandotinib; LY-2784544; 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine. Grades: >98%. CAS No. 1229236-86-5. Molecular formula: C23H25ClFN7O. Mole weight: 469.949. | |
| LY2795050 | LY2795050, a κ-opioid Receptor antagonist, has been found to be effective in imaging KOR behaving as a PET tracer. IC50: 0.72 nM and 25.8 nM for κ-opioid Receptor and κ-opioid. Uses: Ly2795050 is a κ-opioid receptor antagonist that has been found to be effective in imaging kor behaving as a pet tracer. Synonyms: LY2795050; LY 2795050; LY-2795050; (S)-LY2795050; UNII-71PAL357HO; CHEMBL1921842; 71PAL357HO; BDBM50358166. Grades: 98%. CAS No. 1346133-08-1. Molecular formula: C23H22ClN3O2. Mole weight: 407.89. | |
| LY-280748 | LY-280748, a tetrazol derivative, could probably be significant in some studies for its biological activities. Synonyms: LY 280748; LY280748; LY-280748. [1,1'-Biphenyl]-2-ol,5-ethyl-4-[[6-methyl-6-(2H-tetrazol-5-yl)heptyl]oxy]-, sodium salt (1:1); 2-Phenyl-4-ethyl-5-(6-(2H-tetrazol-5-yl)-6-methylheptyloxy)phenol sodium salt; LY-280748; ACMC-20d2d5. Grades: 98%. CAS No. 153226-99-4. Molecular formula: C23H29N4NaO2. Mole weight: 416.50. | |
| LY-281217 | LY-281217 is an organic opioid agonist. It can produce analgesic effects in mice. Uses: Ly-281217 can produce analgesic effects. Synonyms: LY 281217; LY281217; LY-281217. N,N-Di(2-propenyl)-L-Tyr-2-methyl-Ala-2-methyl-Ala-L-Phe-OH;N-[N-[N-(N,N-Di-2-propenyl-L-tyrosyl)-2-methylalanyl]-2-methylalanyl]-L-phenylalanine;(2S)-2-[[2-[[2-[[(2S)-2-[bis(prop-2-enyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;LY281217;L-Phenylalanine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-2-methylalanyl)-. Grades: >99 %. CAS No. 105027-75-6. Molecular formula: C32H42N4O6. Mole weight: 578.71. | |
| LY294002 | LY294002 is a potent inhibitor of phosphoinositide PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively. Synonyms: LY294002; LY-294002; LY 294002; 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; 2-morpholino-8-phenyl-4H-chromen-4-one. Grades: >98%. CAS No. 154447-36-6. Molecular formula: C19H17NO3. Mole weight: 307.349. | |
| LY404039 | LY-404,039, also known as pomaglumetad, is an amino acid analog drug that acts as a highly selective agonist for the metabotropic glutamate receptor group II subtypes mGluR2 and mGluR3. Synonyms: GW786034 HCl; LY-404039; LY 404039; LY404039; LY-404,039; LY404,039; LY 404,039; Pomaglumetad. Grades: >98%. CAS No. 635318-11-5. Molecular formula: C7H9NO6S. Mole weight: 235.22. | |
| LY-411575 | LY-411575, also known as LSN-411575, is a potent, cell-permeable γ-secretase inhibitor (IC50 = 0.078 nM/0.082 nM in membrane-assay/in cell-basedγ-secretase assays) and also inhibits Notch clevage (IC50 = 0.39 nM). Synonyms: LY 411575; LY-411575; LY411575; LSN-411575; LSN 411575; LSN411575. (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide; LY 411,575; LY 411575; LY 450139; LY-411,575; LY-411575; LY411,575; LY411575; LY450139; N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide; N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide; Semagacestat; 209984-57-6. Grades: >98%. CAS No. 209984-57-6. Molecular formula: C26H23F2N3O4. Mole weight: 479.48. | |
| LY 54761 | LY 54761 is a highly potent and discriminating inhibitor employed in the research of cancer. By specifically honing in on tyrosine kinases intricately linked to the progression and spreading of malignant tumors, this remarkable compound block the signal transduction pathways, thus successfully curbing tumor cell proliferation while concurrently triggering apoptosis. Synonyms: 2-(cyclopropylamino)-1-phenylethanone; Lilly 54761; LY 54761; LY-54761; LY54761. Grades: >98%. CAS No. 18381-60-7. Molecular formula: C11H13NO. Mole weight: 175.23. | |
| LY 78335 | LY 78335 is a phenylethanolamine N-methyl transferase (PNMT) inhibitor. Synonyms: Benzenemethanamine, 2,3-dichloro-α-methyl-; 2,3-Dichloro-α-methylbenzenemethanamine; (±)-2,3-Dichloro-α-methylbenzylamine; 1-(2,3-Dichlorophenyl)ethan-1-amine; 2,3-Dichloro-α-methylbenzylamine; DCMB. Grades: ≥95%. CAS No. 39226-94-3. Molecular formula: C8H9Cl2N. Mole weight: 190.07. | |
| LY-79771 | LY-79771 is a antiobesity agent. It can be effective in preventing fat regain following energy deprivation. Uses: Antiobesity agent. Synonyms: LY-79771; LY 79771; LY79771; LY-79771 free base; 4-((S)-3-(((R)-2-hydroxy-2-phenylethyl)amino)butyl)phenol. Grades: 98%. CAS No. 74248-95-6. Molecular formula: C18H23NO2. Mole weight: 285.39. | |
| Lycobetaine | Lycobetaine is a remarkable biomedical innovation engineered to efficaciously study intricate cardiovascular maladies. Harnessing the invaluable attributes derived from bountiful bionatural origins, Lycobetaine proficiently merges indispensable nutritive constituents with potent antioxidants. Synonyms: Lycobetaine. Grades: >98%. CAS No. 72510-04-4. Molecular formula: C16H12NO3. Mole weight: 266.27. | |
| Lysophosphatidylinositols (porcine liver) sodium salt | Lysophosphatidylinositol (LPI) is an endogenous lysophospholipid and a constituent of cell membrane. It is a ligand of GPR55 that activates GPR55 and exhibits anti-inflammatory and antalgic effects. Grades: ≥98%. | |
| M-110 | M-110, a PIM kinases inhibitor, has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of Wnt/β-catenin. IC50: 0.6 to 0.9 uM. Uses: M-110 is a pim kinases inhibitor that has been found to restrain the proliferation of prostate cancer cell lines and also influence the signaling of wnt/β-catenin. Synonyms: M-110; M 110; M110; SCHEMBL16410885; SCHEMBL17821539; N'-[(1E)-1-(4-chloro-6-oxocyclohexa-2,4-dien-1-ylidene)propyl]-2-(3-morpholin-4-ylpropylamino)pyridine-4-carbohydrazide. Grades: 98%. CAS No. 1395048-49-3. Molecular formula: C22H28ClN5O3. Mole weight: 445.95. | |
| M2I-1 | M2I-1 is a protein-protein interaction inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. Synonyms: 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dioneMLS000572003M2I-1; M2I1; M2I 1. Mad2 Inhibitor-1.SMR0001940225-[4-(diisobutylamino)-3-nitrobenzylidene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione6063-97-4AC1METFSMLS003905101CHEMB. CAS No. 312271-03-7. Molecular formula: C19H24N4O4S. Mole weight: 404.48. | |
| Macamide Impurity 2 | Macamide Impurity 2 is an indispensible natural compound extensively applied in the biomedical sector. Synonyms: N-Benzyloleamide. Grades: >98%. CAS No. 883715-21-7. Molecular formula: C25H41NO. Mole weight: 371.6. | |
| Macrozamin | Macrozamin is a natural compound showing teratogenic carcinogenic, mutagenic and neurotoxic properties. Synonyms: (E)-methyl-oxido-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxymethylimino]azanium; beta-D-Glucopyranoside, (methyl-ONN-azoxy)methyl-O-beta-D-xylopyranosyl-; (2-METHYL-2-OXIDODIAZENYL)METHYL 6-O-.BETA.-D-XYLOPYRANOSYL-.BETA.-D-GLUCOPYRANOSIDE.BETA.-D-GLUCOPYRANOSIDE, (2-METHYL-2-OXIDODIAZENYL)METHYL 6-O-.BETA.-D-XYLOPYRANOSYL-. Grades: 98%. CAS No. 6327-93-1. Molecular formula: C13H24N2O11. Mole weight: 384.34. | |
| MADB | It is a novel Trinder's reagent used as a water-soluble reagent for the determination of hydrogen peroxide by enzyme spectrophotometry, and is widely used in diagnostic detection and biochemical test. Synonyms: N,N-Bis(4-sulfobutyl)-3,5-dimethylaniline disodium salt; Sodium 4,4'-((3,5-dimethylphenyl)azanediyl)bis(butane-1-sulfonate). Grades: ≥95%. CAS No. 209518-16-1. Molecular formula: C16H25NNa2O6S2. Mole weight: 437.48. | |
| Madrasin | Madrasin is a potent and cell penetrant as a RNA splicing inhibitor. Uses: A potent and cell penetrant. Synonyms: 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-4(1H)-pyrimidinone. Grades: ≥98%. CAS No. 374913-63-0. Molecular formula: C16H17N5O2. Mole weight: 311.34. | |
| Magnesium ionophore IV | Magnesium ionophore IV is a lipophilic magnesium ionophore. Synonyms: ETH 7025; N,Nμ,Nμμ-Tris[3-(heptylmethylamino)-3-oxopropionyl]-8,8μ-iminodioctylamine; N,N',N''-Tris[3-(heptylmethylamino)-3-oxopropionyl]-8,8μ-iminodioctylamine. CAS No. 135734-39-3. Molecular formula: C49H94N6O6. Mole weight: 863.31. | |
| Magnoflorine chloride | Magnoflorine chloride is an aporphine alkaloid found in flowers of Magnolia liliiflora Desr. It exhibits antioxidant, α-tyrosinase inhibitory and anti-inflammationary activities. Uses: Anti-inflammatory. Synonyms: Magnoflorine, chloride; (6aS)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium chloride; Corytuberine methochloride; Escholine chloride; Thalictrine chloride. Grades: >98%. CAS No. 6681-18-1. Molecular formula: C20H24NO4Cl. Mole weight: 377.87. | |
| Maleimide-PEG4-NHS | This molecular is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds that formed through Maleimide-PEG4-NHS linker are very stable. The NHS ester reacts with amino groups at pH 7-9 to form stable amide bond. In addiction, the maleimide reacts with thiol groups at pH 6.5-7.5 to form stable thiol-ether bond. Maleimide-PEG4-NHS is a very useful linker for various biomolecule crosslinking applications (such as to make ADCs (antibody drug conjugates.)). Uses: Useful linker for various biomolecule crosslinking applications. Synonyms: Maleimide-PEG4-NHS; MAL-PEG4-NHS; Maleimide PEG NHS; MAL-PEG-NHS; Maleimido-Tetra(Ethylene Glycol)?-Acetic Acid NHS ester;2,5-dioxopyrrolidin-1-yl 14-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxatetradecanoate. Grades: 98%. CAS No. 1286754-10-6. Molecular formula: C18H24N2O10. Mole weight: 428.39. | |
| Maltotetraose | Maltotetraose is a resplendent biomedical compound, used for studying diabetes, orchestrating commendable blood glucose regulation. Synonyms: O-α-D-glucopyranosyl-(1?4)-O-α-D-glucopyranosyl-(1?4)-O-α-D-glucopyranosyl-(1?4)-D-Glucose; Amylotetraose; α-1,4-Tetraglucose; a-D-Glucopyranosyl-1,4-O-a-D-glucopyranosyl-1,4-O-a-D-glucopyranosyl-1,4-D-glucopyranose; D-maltotetraose. Grades: ≥95%. CAS No. 34612-38-9. Molecular formula: C24H42O21. Mole weight: 666.58. | |
| Malvidin-3-O-arabinoside chloride | Malvidin-3-O-arabinoside chloride is found in the fruits of Vaccinium myrtillus, it shows antioxidant activity.It has potential preventive effect in colorectal diseases. Synonyms: Malvidin 3-arabinoside. Grades: > 95%. CAS No. 28500-04-1. Molecular formula: C22H23ClO11. Mole weight: 498.87. | |
| Mangafodipir Trisodium | The trisodium salt form of Mangafodipir that has been found to be a contrast agent through intravenously Mangafodipir Trisodium is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. It protects a. Uses: The trisodium salt form of mangafodipir that has been found to be a contrast agent through intravenously mangafodipir trisodium is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (mri) of the liver and it also pr. Synonyms: Mangafodipir (trisodium). Grades: 98%. CAS No. 140678-14-4. Molecular formula: C22H27MnN4Na3O14P2. Mole weight: 757.32. | |
| Manganese dipropionate | Manganese dipropionate (CAS# 21129-18-0 ) is a useful research chemical. Synonyms: Manganese propionate; Propanoic acid, manganese(2+) salt. CAS No. 21129-18-0. Molecular formula: C6H10MnO4. Mole weight: 201.08. | |
| Manzamine A | Manzamine A is an alkaloid in the class of β-carboline isolated from the marine sponges. It acts as an inhibitor of glycogen synthase kinase 3β (GSK3β). It exhibits inhibitory effects against growth of the rodent malaria parasite Plasmodium berghei in vivo. Synonyms: Keramamine A. Grades: ≥98%. CAS No. 104196-68-1. Molecular formula: C36H44N4O. Mole weight: 548.8. | |
| MAO-IN-1 | An inhibitor of monoamine oxidase B (MAO B) (IC50= 20 nM). Synonyms: (2S)-1-[4-[(3-chlorophenyl)methoxy]phenoxy]-3-methoxypropan-2-ol. CAS No. 124991-40-8. Molecular formula: C17H19ClO4. Mole weight: 322.78. | |
| MAOS | MAOS is a modified Trinder's reagent used in hydrogen peroxide determination. Synonyms: 3-[(3,5-Dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt; Sodium 3-[(3,5-dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonate; N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline Sodium Salt. Grades: ≥95%. CAS No. 82692-97-5. Molecular formula: C13H20NNaO4S. Mole weight: 309.36. | |
| Maropitant citrate | Maropitant citrate is a neurokinin receptor antagonist, which was developed as a drug for the treatment of motion sickness and vomiting in dogs. Synonyms: ACIDUM CITRICUM ANHYDRICUM; 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID; B-HYDROXYTRICARBALLYLIC ACID; HYDROXYTRICARBALLYLIC ACID; FEMA 2306; CEFIXIM TELLURITE SUPPLEMENT; CITRATE ION CHROMATOGRAPHY STANDARD; CT SUPPLEMENT. Grades: 95%. CAS No. 359875-09-5. Molecular formula: C38H50N2O9. Mole weight: 678.8. | |
| Matairesinol 4'-O-β-gentiobioside | Matairesinol 4'-O-β-gentiobioside is a lignan found in the herbs of Trachelospermum jasminoides. Synonyms: (3R,4R)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-[[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]methyl]oxolan-2-one. Grades: >98%. CAS No. 106647-14-7. Molecular formula: C32H42O16. Mole weight: 682.672. | |
| Matrixyl 3000 | Matrixyl 3000 is an anti-aging ingredient developed by Sederma. Matrixyl 3000 is a combination of palmitoyl oligopeptide and palmitoyl tetrapeptide-7. Grades: 98%. | |
| MBQ-167 | MBQ-167 is a dual Rac/Cdc42 inhibitor with IC50 values of 103 nM and 78 nM respectively, in metastatic breast cancer cells. It decreases Rac and Cdc42 downstream effector p21-activated kinase (PAK) signaling and the activity of STAT3, without affecting Rho, MAPK, or Akt activities. Synonyms: HY-112842; CS-0066907; 9-ethyl-3-(5-phenyltriazol-1-yl)carbazole. CAS No. 2097938-73-1. Molecular formula: C22H18N4. Mole weight: 338.41. | |
| MC70 | MC70 is a potent and selective modulator of P-glycoprotein(P-gp) with EC50 value of 0.69 μM. It is also an inhibitor of the ABC transporter ABCB1 (aka MDR1). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics. Uses: Mc70 is potential to be used as novel anticancer agent. Synonyms: MC-70; MC 70; MC70. 4-[4-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol;MC-70;4'-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)-[1,1'-biphenyl]-4-ol. Grades: >98 %. CAS No. 1031367-64-2. Molecular formula: C24H25NO3. Mole weight: 375.47. | |
| MC70 hydrochloride | MC70 hydrochloride is the hydrochloride salt form of MC70, which is a potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics. Uses: Anticancer agent. Synonyms: MC70 hydrochloride; MC 70 hydrochloride; MC-70 hydrochloride; 4-[4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]phenyl]phenol hydrochloride. Grades: 98%. Molecular formula: C24H25NO3.HCl. Mole weight: 411.92. | |
| MCC950 | MCC950, also called as CP-456773 or CRID3, is a small molecule that selectively inhibits activation of NLRP3 but does not inhibit NLRC4, AIM2, TLR2 signaling, or priming of NLRP3. MCC950 can be used to treat inflammatory diseases. Synonyms: MCC-950; MCC 950; CP-456773. CAS No. 210826-40-7. Molecular formula: C20H24N2O5S. Mole weight: 404.48. | |
| MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl]-. Grades: >98.0%. CAS No. 1599440-25-1. Molecular formula: C28H36N6O10. Mole weight: 616.62. | |
| MCH (human, mouse, rat) | MCH is an endogenous melanin-concentration hormone receptor agonist with IC50 values of 0.3 and 1.5 nM at MCH1 and MCH2 receptors respectively. It can increase food intake in vivo. Synonyms: Melanin concentrating hormone, human, mouse, rat; Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val. Grades: ≥95% by HPLC. CAS No. 128315-56-0. Molecular formula: C105H160N30O26S4. Mole weight: 2386.84. | |
| MCHr1 antagonist 1 | A selective antagonist of melanin concentrating hormone-1 (MCH1) receptor. Synonyms: 5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester. CAS No. 391610-37-0. Molecular formula: C28H33F2N5O5. Mole weight: 557.59. | |
| MCI826 | MCI-826 potently antagonized LTD4- and LTE4-induced contractions at extremely low concentrations in the isolated guinea pig trachea with pA2 values of 8.3 and 8.9, respectively, on a molar basis. Synonyms: 2,2-diethyl-4-oxo-4-[3-[(E)-2-(4-propan-2-yl-1,3-thiazol-2-yl)ethenyl]anilino]butanoic acid; 2, 2-diethyl-3'- (2- (2- (4-isopropyl) thiazolyl) ethenyl) succinanilic acid; MCI 826; MCI 826, (E)- isomer; MCI-826. CAS No. 140646-80-6. Molecular formula: C22H28N2O3S. Mole weight: 400.53. | |
| McN3716 | An inhibitor of carnitine palmitoyltransferase I (CPT-1). Uses: Hypoglycemic agents. Synonyms: methyl 2-tetradecyloxirane-2-carboxylate; McN 3716; McN-3716; methyl 2-tetradecylglycidate; methyl 2-tetradecyloxiranecarboxylate; methyl palmoxirate. CAS No. 69207-52-9. Molecular formula: C18H34O3. Mole weight: 298.46. | |
| MCOPPB | MCOPPB is a drug which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07 and much weaker activity at other opioid receptors. MCOPPB exhibited potent anxiolytic effects in mouse models, and inhibited signaling through nociceptin receptor in the mouse brain. Synonyms: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole. Grades: >98%. CAS No. 1028969-49-4. Molecular formula: C26H40N4. Mole weight: 408.634. | |
| MCOPPB triHydrochloride | The trihydrochloride salt form of MCOPPB, an effective full agonist of nociceptin receptor, could be a good antianxiety agent with few side-effects. pKi: 10.07. Uses: The trihydrochloride salt form of mcoppb could be a good antianxiety agent with few side-effects. Synonyms: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole; trihydrochloride; MCOPPBtrihydrochloride; 1028969-49-4; 1108147-88-1; 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-Benzimidazoletrihydrochloride. Grades: 95%. CAS No. 1108147-88-1. Molecular formula: C26H40N4.3HCL. Mole weight: 518.01. | |
| MDK19922 | MDK19922, also known as NOD-IN-1 or Compound 4, is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 (IC50= 5.74 μM) and NOD2(IC50= 6.45 μM). Synonyms: ethyl 1-tosyl-1H-indole-2-carboxylate; NOD-IN-1, compound 4; MDK19922; MDK 19922; MDK-19922. CAS No. 132819-92-2. Molecular formula: C18H17NO4S. Mole weight: 343.39. | |
| MDK30165 | MDK30165, also known as K-Ras(G12C) Inhibitor 6, is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. This compound has potential therapeutic application for diseases related to Ras signaling. Synonyms: N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide; K-Ras(G12C) Inhibitor 6; MDK30165; MDK-30165; MDK 30165. CAS No. 2060530-16-5. Molecular formula: C17H22Cl2N2O3S. Mole weight: 405.33. | |
| MDK35833 | MDK35833, also called as Oct3/4-inducer-1, is a potent Oct3/4-inducer, which enhances its transcriptional activity in diverse human somatic cells, implying the possible benefit from using this class of compounds in regenerative medicine. Oct3/4 is suggested to promotes neuronal differentiation of ES cells under neurogenesis-inducing conditions. Synonyms: 4-[(4-Fluorophenyl)methoxy]-benzeneacetonitrile; Oct3/4-inducer-1, MDK35833; MDK-35833; MDK 35833. CAS No. 1016535-83-3. Molecular formula: C15H12FNO. Mole weight: 241.26. | |
| MDL 12330A hydrochloride | MDL 12330A is an adenylyl cyclase inhibitor. It can also inhibit cAMP and cGMP phosphodiesterases, and block slow extracellular and store-operated Ca2+ entry into cells. MDL 12330A can be used to investigate the role of the adenylyl cyclase/cAMP signaling pathway. Synonyms: MDL-12330A; MDL 12330A; MDL12330A; MDL-12330-A; MDL 12330 A; (±)-N-[(1R*,2R*)-2-Phenylcyclopentyl]-azacyclotridec-1-en-2-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 40297-09-4. Molecular formula: C23H36N2.HCl. Mole weight: 377.01. | |
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