BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| L-Lysine-diethylamide dihydrochloride | Synonyms: L-Lysine-diethylamide hydrochloride; (S)-2,6-Diamino-N,N-diethylhexanamide dihydrochloride; Hexanamide, 2,6-diamino-N,N-diethyl-, hydrochloride (1:2), (2S); Hexanamide, 2,6-diamino-N,N-diethyl-, Dihydrochloride, (2S). CAS No. 266356-00-7. Molecular formula: C10H25Cl2N3O. Mole weight: 274.23. |  |
| LM11A 31 dihydrochloride | LM11A-31 is a p75 neurotrophin receptor ligand that can inhibit nerve growth factor binding to p75NTR-F. It can prevent and reverse atrophy of cholinergic neurites and also promote functional recovery in a mouse model of spinal cord injury. Synonyms: (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1243259-19-9. Molecular formula: C12H25N3O2.2HCl. Mole weight: 316.27. | |
| LM 22A4 | LM22A-4 is a selective small-molecule partial agonist of TrkB with IC50 value of 47 nM. It can be used for neurological disease research. LM22A-4 can produce neurogenic and neuroprotective effects in animals. It exhibits beneficial effects on respiration in animal models of Rett syndrome. Synonyms: LM 22A4; LM22A4; LM-22A4; N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide. Grades: ≥98% by HPLC. CAS No. 37988-18-4. Molecular formula: C15H21N3O6. Mole weight: 339.34. | |
| LM985 | LM985, the diethylaminoester derivative of LM975, has anti-tumor activities. Synonyms: 2-(diethylamino)ethyl 2-(4-oxo-2-phenylchromen-8-yl)acetate; flavone acetic acid diethanolamine ester; LM 985; LM 985 hydrochloride; LM-985; LM985; NSC 293015; oxo-4-phenyl-2,4,H-1-benzopyran-8-yl 2-diethylaminoethyl acetate HCl. CAS No. 87626-56-0. Molecular formula: C23H25NO4. Mole weight: 379.45. | |
| L-Moses dihydrochloride | L-Moses dihydrochloride is the first potent, selective and cell-active inhibitor of p300/CBP-associated factor (PCAF) bromodomain (Brd) with a Kd of 126 nM. Synonyms: L-45 dihydrochloride; (1S,2S)-N1,N1-Dimethyl-N2-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-1-phenyl-1,2-propanediamine dihydrochloride; 1,2-Propanediamine, N1,N1-dimethyl-N2-(3-methyl-1,2,4-triazolo[3,4-a]phthalazin-6-yl)-1-phenyl-, (1S,2S)-, hydrochloride (1:2). Grades: ≥95%. Molecular formula: C21H26Cl2N6. Mole weight: 433.38. | |
| LMPTP inhibitor compound 23 | LMPTP inhibitor compound 23 is an inhibitor of low molecular weight tyrosine phosphatase (LMPTP), a proposed insulin receptor phosphatase. This compound has the potential for the treatment of type II diabetes. Synonyms: LMPTP inhibitor 1; N,N-diethyl-4-(4-((3-(piperidin-1-yl)propyl)amino)quinolin-2-yl)benzamide. CAS No. 1908414-82-3. Molecular formula: C28H36N4O. Mole weight: 444.6. | |
| LNK 754 | LNK 754 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: LNK 754; LNK-754; LNK754; CP 609754; CP-609,754. CP609754; 6-[(4-chlorophenyl)-hydroxy-(3-methylimidazol-4-yl)methyl]-4-(3-ethynylphenyl)-1-methylquinolin-2-one;(2R,3R)-2,3-dihydroxybutanedioic acid. Grades: ≥95%. CAS No. 439153-64-7. Molecular formula: C33H28ClN3O8. Mole weight: 630.05. | |
| LNT 1 | LNT 1 is a potent and selective inhibitor of flap endonuclease 1 (FEN1), an enzyme for repair of double-strand breaks in DNA. Synonyms: FEN1-IN-1; FEN1 Inhibitor C1; 1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione. Grades: ≥98% by HPLC. CAS No. 824983-91-7. Molecular formula: C15H12N2O5S. Mole weight: 332.33. | |
| Lobaplatin | Lobaplatin is a diastereometric mixture of platinum(II) complexes identified as a new platinum drug. Its antitumour activity results from the formation of DNA-drug adducts, mainly as GG and AG intra-strand cross-links. Synonyms: D-19466; D 19466; D19466. Grades: >98%. CAS No. 135558-11-1. Molecular formula: C9H18N2O3Pt. Mole weight: 397.328. | |
| Lobetyolin | Lobetyolin is derived from Codonopsis pilosula with antioxidant activity. Uses: Antioxidant. Synonyms: (7E)-2-Hydroxy-1-[(1E)-5-hydroxy-1-penten-1-yl]-7-nonene-3,5-diyn-1-yl b-D-glucopyranoside. Grades: >98%. CAS No. 136085-37-5. Molecular formula: C20H28O8. Mole weight: 396.43. | |
| LOC14 | LOC14 is a protein disulfide isomerase modulator with Kd value of 62 nM. It can force protein disulfide isomerase to adopt an oxidized conformation and suppress its activity. Synonyms: LOC14; LOC-14; LOC 14. 2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one. Grades: ≥98% by HPLC. CAS No. 877963-94-5. Molecular formula: C16H19N3O2S. Mole weight: 317.41. | |
| Locustatachykinin I | Insect tachykinin-related peptide (TRP) isolated from Locusta migratoria. Exhibits sequence homology with vertebrate tachykinins. Synonyms: Glycyl-L-prolyl-L-serylglycyl-L-phenylalanyl-L-tyrosylglycyl-L-valyl-L-argininamide; Lom-TK I; Lom-Tachykinin-1. Grades: ≥98% by HPLC. CAS No. 126985-97-5. Molecular formula: C43H63N13O11. Mole weight: 938.05. | |
| Lodoxamide | Lodoxamide is a potent agonist of GPR35 and an antiallergic drug. It can be used as a mast cell stabilizer for topical administration into eyes indicated for allergic synptom treatment. Uses: Anti-allergic agents. Synonyms: 2-[2-chloro-5-cyano-3-(oxaloamino)anilino]-2-oxoacetic acid. Grades: ≥95%. CAS No. 53882-12-5. Molecular formula: C11H6ClN3O6. Mole weight: 311.6. | |
| LOE 908 hydrochloride | LOE 908 hydrochloride is a broad spectrum cation channel blocker. It can inhibit several cation channels including store-operated calcium channels, voltage-operated calcium channels and so on. LOE 908 hydrochloride can reduce cortical infarct size and improve neurological outcome following middle cerebral artery occlusion. Synonyms: LOE908 hydrochloride; LOE-908 hydrochloride; 3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamide hydrochloride; 1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-, hydrochloride (1:1); 1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-, monohydrochloride; LOE 908 monohydrochloride. Grades: ≥95%. CAS No. 143482-60-4. Molecular formula: C41H48N2O9.HCl. Mole weight: 749.29. | |
| Lomeguatrib | Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment. Synonyms: PaTrin 2; PaTrin2; PaTrin-2; Lomeguatrib; Patrin. O6-(4-bromothenyl)guanine; 6-(4-Bromothenyloxy)-7H-purin-2-amine. CAS No. 192441-08-0. Molecular formula: C10H8BrN5OS. Mole weight: 326.172. | |
| Lometraline HCl | Lometraline, an aminotetralin derivative, is a potential antidepressant and/or anxiolytic agent. Uses: A potential antidepressant and/or anxiolytic agent. Synonyms: 8-chloro-5-methoxy-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride. Grades: ≥98%. CAS No. 34552-78-8. Molecular formula: C13H19Cl2NO. Mole weight: 276.20. | |
| Lomibuvir | Lomibuvir is an nonnucleoside NS5B polymerase inhibitor. It inhibits the 1b/Con1 HCV subgenomic replicon. It binds to the HCV polymerase with dissociation constants of 17 nM. It demonstrated effective antiviral efficacy and may be used for the treatment of HCV. It was developed by ViroChem Pharma, which was acquired by Vertex Pharmaceuticals in 2009. It is in clinical phase 2 with no progress. Uses: Lomibuvir demonstrated effective antiviral efficacy and may be used for the treatment of hcv. Synonyms: 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-; 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid; 5- (3, 3-Dimethyl-1-butynyl) -3-[ (trans-4-hydroxycyclohexyl) [ (trans-4-methylcyclohexyl) carbonyl]amino]thiophene-2-carboxylic acid; VCH 222; VX 222. Grades: >98 %. CAS No. 1026785-55-6. Molecular formula: C25H35NO4S. Mole weight: 445.62. | |
| Lomitapide Mesylate | Lomitapide Mesylate is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia. Synonyms: Lomitapide mesylate; 202914-84-9; BMS 201038-04; Juxtapid; Lomitapide (mesylate). Grades: >98%. CAS No. 202914-84-9. Molecular formula: C40H41F6N3O5S. Mole weight: 789.83. | |
| Lopinavir | An antiretroviral medication acts as a protease inhibitor. It is a co-formulation with a sub-therapeutic dose of ritonavir, as a component of combination therapy to treat HIV/AIDS. Synonyms: ABT 378; ABT-378; ABT378; Aluviran; Kaletra. Grades: ≥98%. CAS No. 192725-17-0. Molecular formula: C37H48N4O5. Mole weight: 628.81. | |
| Lornoxicam | Lornoxicam is a non-steroidal COX-1/COX-2 inhibitor used as an anti-inflammatory drug. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: Chlortenoxicam; Xefocam; Xefo. Grades: > 95%. CAS No. 70374-39-9. Molecular formula: C13H10ClN3O4S2. Mole weight: 371.82. | |
| Losartan Carboxaldehyde | Losartan Carboxaldehyde is a metabolite of Losartan. It is an intermediate in the synthesis of the EXP 3174. Synonyms: 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde; EXP 3179; DUP 167. Grades: > 95%. CAS No. 114798-36-6. Molecular formula: C22H21ClN6O. Mole weight: 420.89. | |
| Losartan Impurity E | An impurity of Losartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure. Synonyms: 5-(4'-Methyl-2-biphenyl)tetrazole; 5-(4'-Methyl[1,1'-biphenyl]-2-yl)-2H-tetrazole; 2-(Tetrazol-5-yl)-4'-methyl-1,1'-biphenyl; 5-[2-(4'-Methylbiphenyl)]tetrazole; L 158507. Grades: > 95%. CAS No. 120568-11-8. Molecular formula: C14H12N4. Mole weight: 236.27. | |
| Losartan Impurity L | N1-Losartanyl-losartan is an impurity found in Losartan tablets. Synonyms: N1-Losartanyl-losartan; 2-Butyl-1-[[2'-[1-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol. Grades: > 95%. CAS No. 230971-71-8. Molecular formula: C44H44Cl2N12O. Mole weight: 827.81. | |
| Losartan Impurity M | N2-Losartanyl-losartan is an impurity found in Losartan tablets. Synonyms: N2-Losartanyl-losartan; 2-Butyl-1-[[2'-[2-[[2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-5-yl]methyl]-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-4-chloro-1H-imidazole-5-methanol. Grades: > 95%. CAS No. 230971-72-9. Molecular formula: C44H44Cl2N12O. Mole weight: 827.81. | |
| Losartan Potassium Salt | Losartan is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. It promotes vasodilatation and counteracts the effects of aldosterone thus can be used as an antihypertensive. Uses: Antihypertensive. Synonyms: MK 954; MK954; MK-954; Cozaar; Lorzaar; Losaprex; Hyzaar; [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol. Grades: >98%. CAS No. 124750-99-8. Molecular formula: C22H23ClKN6O. Mole weight: 462.01. | |
| Lotrafiban hydrochloride | The hydrochloride salt form of Lotrafiban, a benzodiazepine derivative, has been found to be a platelet glycoprotein IIb/IIIa blocker and was once studied in cardiovascular disorders. Synonyms: Lotrafiban hydrochloride; Lotrafiban HCl; Lotrafiban hydrochloride; 2-[(2S)-4-methyl-3-oxo-7-(4-piperidin-4-ylpiperidine-1-carbonyl)-2,5-dihydro-1H-1,4-benzodiazepin-2-yl]acetic acid;hydrochloride. Grades: 98%. CAS No. 179599-82-7. Molecular formula: C23H33ClN4O4. Mole weight: 464.99. | |
| Loureirin D | Loureirin D is a chalcone isolated from Dracaena cochinchinensis. Grades: 98%. CAS No. 119425-91-1. Molecular formula: C16H16O5. Mole weight: 288.29. | |
| Loxiglumide | Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. Uses: Loxiglumide stimulates calorie intake and hunger feelings in humans. it inhibits pancreatic secretion of digestive enzymes. Synonyms: CR-1505; CR 1505; CR1505; D,L-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pentanoicacid;Pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino);CR-1505;CR1505;4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid. Grades: 95%. CAS No. 107097-80-3. Molecular formula: C21H30Cl2N2O5. Mole weight: 461.38. | |
| LOXO-101 sulfate | The sulfate salt form of LOXO-101, also called Larotrectinib, which is an ATP-competitive inhibitor of tropomyosin receptor kinases. It was approved by FDA for the treatment of metastatic solid tumors. Synonyms: LOXO-101 sulfate; LOXO 101 sulfate; LOXO101 sulfate; Larotrectinib sulfate; (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide sulfate. Grades: >95%. CAS No. 1223405-08-0. Molecular formula: C21H24F2N6O6S. Mole weight: 526.51. | |
| LP-922761 | LP-922761 is a potent AAK1 inhibitor (IC50 values are 4.8 and 7.6 nM in enzyme and cell assays, respectively). Synonyms: tert-Butyl (2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)(methyl)carbamate. Grades: ≥98% by HPLC. CAS No. 1454808-95-7. Molecular formula: C21H26N6O3. Mole weight: 410.47. | |
| LP-935509 | LP-935509 is a brain penetrant inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50 value 3.3 nM and 14 nM and 320 nM for the closely related BIKE and GAK enzymes, repsectively). LP-935509 exhibits antinociceptive property in multiple rat models of neuropathic pain, but not acute pain. The antinociception of AAK1 inhibitor can be blocked by α2 adrenergic antagonists. Uses: Antinociceptive agent. Synonyms: LP935509; LP 935509; LP-935509; Isopropyl 4-(3-(2-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)piperazine-1-carboxylate; 4-[3-(2-Methoxy-pyridin-3-yl)-pyrazolo[1,5-a]pyrimidin-5-yl]-piperazine-1-carboxylic acid isopropyl ester. Grades: 99%. CAS No. 1454555-29-3. Molecular formula: C20H24N6O3. Mole weight: 396.44. | |
| LPA2 antagonist 1 | LPA2 antagonist 1 could block the Erk activation regulated by LPA(2) and proliferation of HCT-116 cells as a selective inhibitor of LPA2 protein. IC50: 17 nM (in vitro). It could also be used to assess the inhibiting effection in the process of anticancer. Uses: Lpa2 antagonist 1 could block the erk activation regulated by lpa(2) and proliferation of hct-116 cells as a selective inhibitor of lpa2 protein. Synonyms: LPA2 antagonist 1; CHEMBL256470; BDBM50373826; AKOS027314118; CS-3103; AK298931; MDK6664; MDK-6664; MDK 6664; LPA2-IN-1. Grades: 95%. CAS No. 1017606-66-4. Molecular formula: C20H23Cl2N5O2S2. Mole weight: 500.46. | |
| L-Penicillamine | L-Penicillamine is a medication primarily used for the treatment of Wilson's disease. Synonyms: 3-Mercapto-L-valine; (+)-Penicillamine; (R)-Penicillamine; NSC 241261; Penicillamine L-form; L-(+)-beta-Mercaptovaline; 3,3-Dimethyl-L-cysteine; L-Pen; (R)-2-Amino-3-mercapto-3-methylbutanoic acid. Grades: ≥ 98% by HPLC. CAS No. 1113-41-3. Molecular formula: C5H11NO2S. Mole weight: 149.21. | |
| LpxC inhibitor 1a | LpxC inhibitor 1a is a potent LpxC inhibitor (IC50 = 1.37 nm) commonly used as an antibacterial agent for the treatment of gram-negative infections. Uses: An antibacterial agent for the treatment of gram-negative infections. Synonyms: PF-04753299; PF 04753299; PF04753299; (2R)-N-hydroxy-2-methyl-2-methylsulfonyl-4-(4-phenylphenyl)butanamide. Grades: 99%. CAS No. 1289620-49-0. Molecular formula: C18H21NO4S. Mole weight: 347.43. | |
| LQZ-7I | LQZ-7I is a survivin targeted inhibitor that can inhibit the growth of xenograft tumors and induce the loss of survivin in the tumor. Synonyms: N2,N3-Bis(4-Fluorophenyl)Quinoxaline-2,3-Diamine; N,N'-Bis(4-Fluorophenyl)Quinoxaline-2,3-Diamine. Grades: 98%. CAS No. 195822-23-2. Molecular formula: C20H14F2N4. Mole weight: 348.3. | |
| LRE1 | LRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM) that prevents sAC-dependent processes in cellular and physiological systems via occupying the binding site of the physiological activator HCO3-. LRE1 also inhibits cAMP accumulation in 4-4 cells (IC50 value 11 μM). Synonyms: 6-Chloro-N4-cyclopropyl-N4-(2-thienylmethyl)-2,4-pyrimidinediamine; RU0204277; LRE1; RU 0204277; LRE 1; RU-0204277; LRE-1. Grades: 98%. CAS No. 1252362-53-0. Molecular formula: C12H13ClN4S. Mole weight: 280.78. | |
| L-(+)-Rhamnose Monohydrate | L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria. Unlike most natural sugars, it is found in an L configuration instead of the usual D configuration. Synonyms: 6-Deoxy-L-mannose; a-L-Rhamnose monohydrate. Grades: >98%. CAS No. 10030-85-0. Molecular formula: C6H12O5 H2O. Mole weight: 182.17. | |
| L-rhamnulose | L-rhamnulose is the eminent compound, aiding in elucidating perplexing metabolic disorders and facilitating avant-garde drug development. This saccharide derivative orchestrates an array of intricate biochemical reactions used in studying afflictions such as diabetes, obesity and the enigmatic metabolic syndrome. Synonyms: 6-deoxy-L-fructose; rhamnulose; 6-deoxy-L-arabino-hex-2-ulose. CAS No. 14807-05-7. Molecular formula: C6H12O5. Mole weight: 164.16. | |
| LSD Inhibitor I | LSD Inhibitor I is an inhibitor of lysine-specific demethylase 1 (LDS1), displaying potential antitumor activity. It binds to and inhibits LDS1, resulting in an increase of H3K4 methylation and the expression of tumor-suppressor genes. Synonyms: Lysine-specific Demethylase Inhibitor (1C) hydrochloride; KDM1 Inhibitor I. Grades: ≥95%. CAS No. 1234494-75-7. Molecular formula: C15H36N8·4HCl. Mole weight: 474.34. | |
| L-Sulforaphane | L-Sulforaphane is a compound with isothiocyanate group found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbages. It has been shown to regulate phase II detoxifying enzymes and induce cell cycle arrest or apoptosis in malignant cells in vitro and in vivo, thus can be potentially used as an antioxidant and anticancer agent. Uses: Anticarcinogenic agents. Synonyms: (R)-Sulforaphane; 4-Methylsulfinylbutyl isothiocyanate. Grades: ≥98%. CAS No. 142825-10-3. Molecular formula: C6H11NOS2. Mole weight: 177.3. | |
| L-Tetrahydrofolic Acid | Tetrahydrofolic acid is a folic acid derivative. It is a cofactor in many bio-reactions, especially in the metabolism of amino acids and nucleic acids. Uses: A cofactor in many bio-reactions, especially in the metabolism of amino acids and nucleic acids. Synonyms: N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; (-)-L-5,6,7,8-Tetrahydrofolic Acid; THFA; Tetrahydropteroylglutamic Acid. Grades: ≥70% (when packaged). CAS No. 135-16-0. Molecular formula: C19H23N7O6. Mole weight: 445.43. | |
| L-threo Lysosphingomyelin (d18:1) | L-threo Lysosphingomyelin (d18:1) is an endogenous bioactive sphingolipid and an agonist of sphingosine-1-phosphate (S1P) receptors 1-3. Synonyms: L-threo Lyso SM (18:1); L-threo Lysosphingomyelin (18:1); L-threo Sphingosine-1-Phosphocholine (d18:1); L-threo-Sphingosylphosphorylcholine; [(E,2S,3S)-2-amino-3-hydroxyoctadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate. Grades: ≥98%. CAS No. 105615-55-2. Molecular formula: C23H49N2O5P. Mole weight: 464.62. | |
| L-Thyroxine sodium salt pentahydrate | L-Thyroxine sodium salt pentahydrate is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. It reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints. It was also used to study the light-induced hormone conversion of T4 to T3 in regulation of photoperiodic response of gonads in Japanese quail. Synonyms: Sodium levothyroxine pentahydrate. Grades: >98%. CAS No. 6106-7-6. Molecular formula: C15H20I4NNaO9. Mole weight: 888.93. | |
| L-trans-2,4-PDC | L-trans-2,4-PDC is a competitive, transportable inhibitor of L-glutamate transport (Ki = 4.6 μM in rat brain synaptosomes). Uses: Neurotransmitter uptake inhibitors. Synonyms: L-trans-Pyrrolidine-2,4-dicarboxylic acid. Grades: ≥97% by HPLC. CAS No. 64769-66-0. Molecular formula: C6H9NO4. Mole weight: 159.14. | |
| L-tryptophyl-L-lysyl-L-tyrosyl-L-methionyl-L-valyl-L-methioninamide | WKYMVM is a selective agonist for the formyl peptide receptors FPR2 and FPR3 that is expressed on immune cells. WKYMVM induces calcium mobilization in FPR2-HL-60 cells and FPR3-HL-60 cells (EC50 = 2 and 80 nM, respectively). CAS No. 187986-11-4. Molecular formula: C41H61N9O7S2. Mole weight: 856.11. | |
| LTV-1 | LTV-1, a highly potent inhibitor, inhibits LYP((IC50 = 508 nM)) in a dose-dependent manner at low- and sub-micromolar concentrations in T cells. Uses: Potent, cell-permeable and reversible inhibitor of lymphoid tyrosine phosphatase. Synonyms: LTV-1; LTV 1; LTV1; 3-[ (4-{ (E) -[1- (2-Methylphenyl) -4, 6-dioxo-2-thioxotetrahydro-5 (2H) -pyrimidinylidene]methyl}phenoxy) methyl]benzoic acid. Grades: ≥98%. CAS No. 347379-29-7. Molecular formula: C26H20N2O5S. Mole weight: 472.51. | |
| L-Tyrosine-diethylamide hydrochloride | Synonyms: (S)-2-Amino-N,N-diethyl-3-(4-hydroxyphenyl)propanamide; Benzenepropanamide, α-amino-N,N-diethyl-4-hydroxy-, (αS); (αS)-α-Amino-N,N-diethyl-4-hydroxybenzenepropanamide; (2S)-2-Amino-N,N-diethyl-3-(4-hydroxyphenyl)propanamide. Molecular formula: C13H21ClN2O2. Mole weight: 272.77. | |
| Lubabegron | Lubabegron is a β3-adrenoreceptor agonist. Uses: β3-adrenoreceptor agonist. Synonyms: LY488756; LY-488756; LY 488756; Lubabegron; 2-[4-[2-[[(2S)-2-hydroxy-3-(2-thiophen-2-ylphenoxy)propyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carbonitrile. Grades: ≥98%. CAS No. 391920-32-4. Molecular formula: C29H29N3O3S. Mole weight: 499.62. | |
| Lucidenic acid A | Lucidenic acid A, a naturally occurring compound found in Ganoderma lucidum fruiting bodies, displays immense therapeutic potential. It exhibits anti-inflammatory, anti-tumor, and anti-diabetic properties as evidenced by various studies. Additionally, it significantly impacts physiological parameters such as blood pressure, cholesterol, and blood sugar. The multifaceted activities of Lucidenic acid A render it an ideal candidate for treating chronic inflammatory diseases, diabetes, and cancer. Synonyms: lucidenic acid A; 95311-94-7; LucidenicacidA; Lucideric acid A; (4R)-4-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid; CHEMBL460969; SCHEMBL6522668; CHEBI:172690; DTXSID401316662; HY-N6862; BDBM50356926; AKOS037515140; AC-34115; MS-28395; CS-0027808; D85042; 7beta-hydroxy-4,4,14alpha-trimethyl-3,11,15-trioxo-5alpha-chol-8-en-24-oic acid. Grades: >98%. CAS No. 95311-94-7. Molecular formula: C27H38O6. Mole weight: 458.59. | |
| Lucidenic acid B | Lucidenic acid B, an organic compound hailing from Ganoderma lucidum, is praised for its multifaceted biomedical properties. From combating neoplasms to alleviating inflammations, this natural triterpenoid holds great promise in treating debilitating conditions such as breast and prostate cancers and an array of inflammatory disorders. Synonyms: Lucidenic acid B; (5alpha,7beta,12beta)-7,12-Dihydroxy-4,4,14-trimethyl-3,11,15-trioxo-chol-8-en-24-oic acid. Grades: >98%. CAS No. 95311-95-8. Molecular formula: C27H38O7. Mole weight: 474.58642. | |
| Lucidenic acid C | Lucidenic acid C, an organic compound derived from the fungus Ganoderma lucidum, exhibits multifaceted pharmacological actions such as antioxidant, anti-inflammatory, immunomodulatory, and anticancer properties. Novel studies have elucidated that this naturally occurring triterpene exhibits profound inhibition of malignancy development and metastasis in cancer cells. The promising therapeutic potential of lucidenic acid C extends beyond oncology, offering a plethora of therapeutic applications in diverse pathological conditions. Synonyms: Lucidenic acid C; (3beta,5alpha,7beta,12beta)-3,7,12-Trihydroxy-4,4,14-trimethyl-11,15-dioxo-chol-8-en-24-oic acid. Grades: >98%. CAS No. 95311-96-9. Molecular formula: C27H40O7. Mole weight: 476.6023. | |
| Lucidenic acid E | Lucidenic acid E, a triterpenoid derived from Ganoderma lucidum, exhibits potent anti-inflammatory, anti-tumor and anti-diabetic activities. Notably, it has demonstrated the ability to impede in vitro cancer cell growth, indicating its potential therapeutic value. Its hepatoprotective and antioxidant effects further increase the promise of lucidenic acid E in the treatment of liver ailments. Such multifaceted properties of this natural compound highlight its potential in the development of novel therapies. Synonyms: Lucidenic Acid E2; Lucidenic acid E. Grades: >98%. CAS No. 98665-17-9. Molecular formula: C29H40O8. Mole weight: 516.631. | |
| Lucidenic acid LM1 | Lucidenic acid LM1, a triterpenoid compound, is obtained from medicinal fungi that are fit for consumption. Numerous biological activities have been ascertained to be associated with this compound such as anti-cancer, anti-inflammatory, and anti-fibrotic effects. The inhibition of human liver cancer and breast cancer cells are among the effects of Lucidenic acid LM1, which suggests its potential candidacy for the development of new anti-cancer drugs. Synonyms: (3beta,5alpha,7beta)-3,7-dihydroxy-4,4,14-trimethyl-11,15-dioxochol-8-en-24-oic acid. Grades: >98%. CAS No. 364622-33-3. Molecular formula: C27H40O6. Mole weight: 460.6. | |
| Lucidin | Lucidin is a natural component of Rubia tinctorum L. It exhibits antibacterial activity. Synonyms: Henine; NSC 30546; NSC30546; NSC-30546. Grades: >98%. CAS No. 478-08-0. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| Lucyoside B | Lucyoside B is a triterpenoid compound found in the herbs of Luffa cylindrica ROEM. Synonyms: Arjunolitin; Asterbatanoside C; (2alpha,3beta,4alpha)-3-(beta-D-Glucopyranosyloxy)-2,23-dihydroxy-olean-12-en-28-oic acid beta-D-glucopyranosyl ester. Grades: >98%. CAS No. 91174-19-5. Molecular formula: C42H68O15. Mole weight: 812.99. | |
| LUF 6283 | LUF 6283 is a partial hydroxycarboxylic acid receptor 2 agonist. It can effectively lower plasma lipid levels. Synonyms: LUF6283, LUF-6283, LUF 6283; 5-Butyl-1H-pyrazole-3-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 92933-48-7. Molecular formula: C8H12N2O2. Mole weight: 168.19. | |
| Lufotrelvir | Lufotrelvir is a small molecule prodrug that targets 3CLpro protease (Mpro), an enzyme used by viruses like SARS-CoV-2 to assemble and multiply. Once administered through intravenous infusion, It is cleaved into PF-00835231 to exert its antiviral effects. Synonyms: (3S)-3-[(2S)-2-(4-methoxy-1H-indole-2-carboxamido)-4-methylpentanamido]-2-oxo-4-[(3S)-2-oxopyrrolidin-3-yl]butyl dihydrogen phosphate; Lufotrelvirum; PF-07304814; PF07304814; PF 07304814; GTPL11249; (3S)-3-({N-[(4-methoxy-1H-indol-2-yl)carbonyl]-L-leucyl}amino)-2-oxo-4-[(3S)-2-oxopyrrolidin-3-yl]butyl dihydrogen phosphate; 1H-Indole-2-carboxamide, 4-methoxy-N-[ (1S) -3-methyl-1-[[[ (1S) -2-oxo-1-[[ (3S) -2-oxo-3-pyrrolidinyl]methyl]-3- (phosphonooxy) propyl]amino]carbonyl]butyl]-. Grades: >98%. CAS No. 2468015-78-1. Molecular formula: C24H33N4O9P. Mole weight: 552.51. | |
| Lumacaftor | Lumacaftor is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF). Lumacaftor may act to restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, the defective cell membrane protein responsible for the progression of CF. Lumacaftor defects in the CFTR protein affect the transport of chloride and other ions across cells, and lead to the accumulation of thick, sticky mucus in the lungs of patients with CF. This mucus fosters chronic infection and inflammation, and results in irreversible lung damage. Synonyms: VX-809; VX809; VX 809; VRT 826809; VRT826809; VRT-826809. Grades: ≥98%. CAS No. 936727-05-8. Molecular formula: C24H18F2N2O5. Mole weight: 452.41. | |
| Lunasin | Lunasin is a novel, cancer-preventive peptide whose efficacy against chemical carcinogens and oncogenes has been demonstrated in mammalian cells and in a skin cancer mouse model. Grades: 95%. | |
| Lup-20(29)-en-28-oic acid, 3-[ D-glucopyranosyl(1?4)[ L-rhamnopyranosyl) (1?2)-L-arabinopyranosyl]oxy], (3,4)-) | Lup-20(29)-en-28-oic acid, 3-[ D-glucopyranosyl(1?4)[ L-rhamnopyranosyl) (1?2)-L-arabinopyranosyl]oxy], (3,4)-) is extracted from Pulsatilla chinensis (Bunge) Regel. Synonyms: Betulinic acid 3beta-O-alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-alpha-L-arabinopyranoside. Grades: >98%. CAS No. 848784-87-2. Molecular formula: C47H76O16. Mole weight: 897.1. | |
| Luxeptinib | Luxeptinib is a tyrosine kinase inhibitor, with antineoplastic activity. Synonyms: N-{3-fluoro-4-[7-(4-methyl-1H-imidazol-2-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-N'-(2,4,6-trifluorophenyl)urea; NSC-791692; Urea, N-[4-[2,3-dihydro-7-(5-methyl-1H-imidazol-2-yl)-1-oxo-1H-isoindol-4-yl]-3-fluorophenyl]-N'-(2,4,6-trifluorophenyl)-. CAS No. 1616428-23-9. Molecular formula: C25H17F4N5O2. Mole weight: 495.43. | |
| L-Valacyclovir Hydrochloride | Valaciclovir HCl is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Synonyms: Valacyclovir hydrochloride; Valacyclovir HCl. Grades: >98%. CAS No. 124832-27-5. Molecular formula: C13H20N6O4.HCl. Mole weight: 360.8. | |
| LX7101 hydrochloride | LX7101 is a dual inhibitor of LIM kinase (LIMK) and Rho-associated kinase (ROCK) with IC50 values of 32, 4.3, 69, and 32 nM for LIMK1, LIMK2, ROCK1 and ROCK2, respectively. It has been identified as a candidate for the treatment of ocular hypertension and associated glaucoma due to its high efficacy and good safety profile. Synonyms: LX7101 HCl; [3-[[4-(aminomethyl)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carbonyl]amino]phenyl] N,N-dimethylcarbamate hydrochloride. Grades: ≥98%. Molecular formula: C23H29N7O3·HCl. Mole weight: 488. | |
| L-Xylulose | L-Xylulose, an organic sugar alcohol, finds significant utility within the dynamic biomedicine sector as a crucial carbohydrate source and an intermediary compound in the synthesis of pharmaceuticals and biochemicals. Synonyms: L-threo-Pentulose; L-threo-2-Pentulose; L-threo-pent-2-ulose. CAS No. 527-50-4. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| LY-113174 | LY-113174 is a novel class of nonsteroidal aromatase inhibitor. It may prove useful in the treatment of estrogen-dependent diseases. Uses: Ly-113174 may prove useful in the treatment of estrogen-dependent diseases. Synonyms: 5H-Indeno[1,2-d]pyrimidine,8-chloro-5-(4-chlorophenyl)-;8-Chloro-5-(4-chlorophenyl)-5H-indeno[1,2-d]pyrimidine; LY 113174; LY113174; LY-113174. Grades: >98%. CAS No. 112959-07-6. Molecular formula: C17H10Cl2N2. Mole weight: 313.18. | |
| LY 117413 | LY 117413 is a bio-active chemical,but no detailed information has been published yet. Synonyms: LY 117413; LY117413; LY-117413; Lilly 117413. 4-(3-hydroxyphenyl)-3,4-dimethyl-alpha-phenyl- 1-Piperidinepropanol. Grades: 98%. CAS No. 82970-70-5. Molecular formula: C22H29NO2. Mole weight: 339.48. | |
| LY 135114 | LY 135114 is a metabolite of LY 195448. LY195448 is a Alpha adrenergic receptor originate by Eli Lilly. But clinical trials for the treatment of cancer had been discontinued. Uses: Ly 135114 is a metabolite of ly 195448. Synonyms: LY 135114; LY135114; LY-135114. 3-[3-[[2-hydroxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methylbutyl]benzamide. Grades: 98%. CAS No. 126254-82-8. Molecular formula: C20H26N2O3. Mole weight: 342.43. | |
| LY 135305 | LY 135305 is a bio-active molecular under the development of Eli Lilly. It can inhibit spontaneous lung metastasis in a dose-dependent manner. Uses: Tumor. Synonyms: LY 135305; LY135305; LY-135305. beta-phenyl-1-Naphthalenepropanamine hydrochloride. Grades: 98%. CAS No. 123199-75-7. Molecular formula: C19H20ClN. Mole weight: 297.82. | |
| LY 137150 | LY 137150 is a bio-active chemical, but no detailed information has been published yet. Synonyms: LY 137150; LY137150; LY-137150. 2-(2-Methoxy-4-(methylthiol)phenyl)-1H-imidazo-(4,5-c)pyridine hydrochloride. Grades: 98%. CAS No. 86315-69-7. Molecular formula: C14H14ClN3OS. Mole weight: 307.80. | |
| LY 140091 | LY 140091 is a bio-active chemical, but no detailed information has been published yet. Synonyms: LY 140091; LY140091; LY-140091. (Z)-3-((5-methoxy-3-oxo-2(3H)-benzofuranylidene)methyl)-Benzoic acid. Grades: 98%. CAS No. 74814-56-5. Molecular formula: C17H12O5. Mole weight: 296.27. | |
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