BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| LBM-415 | LBM415 (NVP PDF-713), a novel peptide deformylase inhibitor, was tested by reference methods against 2 collections of pathogenic Neisseria being developed for clinical trials as a parenteral and oral agent for treatment of community-acquired respiratory tract disease and serious infections caused by antimicrobial-resistant gram-positive cocci. I. Uses: Pdf inhibitor. Synonyms: LBM-415; LBM 415; LBM415; NVP-PDF-713. (2S) -1- ( (2R) -2- ( (Formylhydroxyamino) methyl) hexanoyl) pyrrolidine-2-carboxylic acid N-(5-fluoro-1-oxopyridin-2-yl)amide. Grades: ≥98%. CAS No. 478913-91-6. Molecular formula: C18H25FN4O5. Mole weight: 396.41. |  |
| L-Buthionine sulfoximine | L-Buthionine sulfoximine is an irreversible glutathione-synthesis inhibitor developed as a chemotherapeutic agent. It inhibits glutathione biosynthesis and causes depletion of cellular glutathione levels. Study showed that L-Buthionine sulfoximine synergistically enhanced melphalan activity (inducing 2-4 logs of cell kill) against multiple myeloma cell lines. Synonyms: L-Buthionine-(S,R)-Sulfoximine; (2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid. Grades: ≥98% by HPLC. CAS No. 83730-53-4. Molecular formula: C8H18N2O3S. Mole weight: 222.3. | |
| L-Carnitine | L-carnitine is a constituent striated muscle and liver, and also a cofactor involved in fatty acid metabolism for transporting fatty acids through the inner mitochondrial membrane. It also acts as an inhibitor of HDAC. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Levocarnitine; Vitamin BT; (R)-Carnitine; Carnitor; ST-198; ST 198; ST198; (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate. Grades: 98%. CAS No. 541-15-1. Molecular formula: C7H15NO3. Mole weight: 161.201. | |
| LCS-1 | LCS-1 is an inhibitor superoxide dismutase 1 (SOD1) inhibitor, catalyzing the conversion of superoxide ion (O2-) into H2O2 and O2 to maintain low levels of reactive oxygen species. LCS-1 can prevent serum-induced activation of the ERK and PI 3-kinase/AKT signaling pathways and inhibit the proliferation of lung adenocarcinoma cell lines. Synonyms: LCS-1; LCS 1; LCS1; 4,5-Dichloro-2-(m-tolyl)pyridazin-3(2H)-one; 4,5-Dichloro-2-(3-methylphenyl)pyridazin-3-one. Grades: 99%. CAS No. 41931-13-9. Molecular formula: C11H8Cl2N2O. Mole weight: 255.1. | |
| L-Cystine dimethyl ester dihydrochloride | L-Cystine dimethyl ester dihydrochloride serves as an efficacious antioxidant, exhibiting commendable immunomodulatory, metabolic and cytoprotective potential. Its application is extended towards abating oxidative stress, addressing cardiovascular complications, and counteracting hepatic insult instigated by noxious agents. In essence, this compound offers a multifaceted therapeutic approach to sustain homeostatic balance in cellular milieu. Synonyms: Dimethyl L-cystinate dihydrochloride; (2R,2'R)-Dimethyl 3,3'-disulfanediylbis(2-aminopropanoate) dihydrochloride; Dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate) dihydrochloride; NSC 161614; L-cysteine methyl ester (1->1')-disulfide compound with L-cysteine methyl ester hydrochloride. Grades: >95%. CAS No. 32854-09-4. Molecular formula: C8H18Cl2N2O4S2. Mole weight: 341.28. | |
| LDCA | LDCA is a dual-hit metabolic modulator and inhibits LDH-A enzyme activity to stimulate apoptosis in the malignant population. LDCA can be used for the research of oncogenic progression. Synonyms: 2,2-Dichloro-N-(3-chloro-4-fluorophenyl)acetamide. CAS No. 349106-80-5. Molecular formula: C8H5Cl3FNO. Mole weight: 256.49. | |
| LDN-192960 hydrochloride | LDN-192960 is an inhibitor of haspin protein kinase and dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) with IC50 values of 10 and 48 nM, respectively. Synonyms: LDN192960 dihydrochloride; LDN 192960 dihydrochloride; LDN-192960 2HCl; 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochloride. Grades: ≥98%. CAS No. 2309172-48-1. Molecular formula: C18H20N2O2S·2HCl. Mole weight: 401.4. | |
| LDN 193188 | LDN 193188 is a phosphatidylcholine transfer protein inhibitor. It regulates hepatic glucose metabolism and can be used in the management of hepatic insulin resistance. Synonyms: LDN-193188; LDN 193188; LDN193188; 2, 4-Dichloro-N- [ [ [4- [ [ (4, 6-dimethyl-2-pyrimidinyl) amino] sulfonyl] phenyl] amino] carbonyl] benzamide. Grades: ≥99% by HPLC. CAS No. 1267610-30-9. Molecular formula: C20H17Cl2N5O4S. Mole weight: 494.35. | |
| LDN-193189 | LDN193189 is a selective and potent ALK inhibitor with potential anticancer activity. Uses: Differentiation. Synonyms: 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline; LDN193189; LDN 193189; LDN-193189. Grades: 0.98. CAS No. 1062368-24-4. Molecular formula: C25H22N6. Mole weight: 406.48238. | |
| LDN 209929 dihydrochloride | Cas No. 1233355-57-1. | |
| LDN-212854 | LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2. LDN-212854 exhibits some selectivity for ALK2 in preference to other BMP type I receptors, ALK1 and ALK3, which may permit the interrogation of ALK2-mediated signaling, transcriptional activity, and function. LDN-212854 potently inhibits heterotopic ossification in an inducible transgenic mutant ALK2 mouse model of fibrodysplasia ossificans progressiva. Synonyms: BMP Inhibitor III; LDN 212854; 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. Grades: >98%. CAS No. 1432597-26-6. Molecular formula: C25H22N6. Mole weight: 406.48. | |
| LDS 867 | LDS 867 is a potent and selective protein kinase D (PKD) inhibitor used in the biomedical industry for research on cancer treatment. It effectively inhibits PKD and displays anticancer activity against a range of malignancies, including breast and pancreatic cancers. LDS 867 is a valuable tool in the study of PKD signaling pathways and potential therapeutic strategies for various diseases. Synonyms: Benzothiazolium, 2-[[4-[4-[4-(dimethylamino)phenyl]-1,3-butadienyl]-2H-1-benzopyran-2-ylidene]methyl]-3-ethyl perchlorate. CAS No. 106025-71-2. Molecular formula: C31H29N2OS?ClO4. Mole weight: 577.1. | |
| Lecirelin | Lecirelin is a synthetic gonadotropin releasing hormone (GnRH) analogue. It is a medication commonly used in veterinary medicine. Synonyms: (D-Tle6)-Leuprolide; (D-Tle6)-Leuprorelin; Dalmarelin. CAS No. 61012-19-9. Molecular formula: C59H84N16O12. Mole weight: 1209.42. | |
| Ledaborbactam | Ledaborbactam is a beta-lactamase inhibitor. Synonyms: (3R)-2-hydroxy-3-(propanamido)-3,4-dihydro-2H-1,2-benzoxaborinine-8-carboxylic acid; VNRX-7145 acid; VNRX-7145 active metabolite; (3R)-3,4-Dihydro-2-hydroxy-3-((1-oxopropyl)amino)-2H-1,2-benzoxaborin-8-carboxylic acid; 2H-1,2-Benzoxaborin-8-carboxylic acid, 3,4-dihydro-2-hydroxy-3-[(1-oxopropyl)amino]-, (3R)-. CAS No. 1842397-36-7. Molecular formula: C12H14BNO5. Mole weight: 263.06. | |
| Ledaborbactam Etzadroxil | Ledaborbactam Etzadroxil is a beta-lactamase inhibitor. Synonyms: [(2-ethylbutanoyl)oxy]methyl (3R)-2-hydroxy-3-(propanamido)-3,4-dihydro-2H-1,2-benzoxaborinine-8-carboxylate; VNRX-7145; 2H-1,2-Benzoxaborin-8-carboxylic acid, 3,4-dihydro-2-hydroxy-3-((1-oxopropyl)amino)-, (2-ethyl-1-oxobutoxy)methyl ester, (3R)-; [(2-Ethylbutanoyl)oxy]methyl (3R)-2-hydroxy-3-(propionylamino)-3,4-dihydro-2H-1,2-benzoxaborinine-8-carboxylate. CAS No. 1842399-68-1. Molecular formula: C19H26BNO7. Mole weight: 391.22. | |
| LEI-106 | LEI-106 is a potent inhibitor of sn-1 DAGLα (IC50 = 18 nM). It inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6 in mouse brain membrane homogenates and in HEK293T cell membrane preparations. Synonyms: 2-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]acetic acid. Grades: ≥98%. CAS No. 1620582-23-1. Molecular formula: C26H27NO6S. Mole weight: 481.6. | |
| Lenalidomide hemihydrate | Lenalidomide hemihydrate (CC-5013 hemihydrate) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. Synonyms: Revlimid hemihydrate; CC-5013 hemihydrate. Grades: >98%. CAS No. 847871-99-2. Molecular formula: C26H28N6O7. Mole weight: 268.27. | |
| Lenalidomide hydrochloride | Lenalidomide hydrochloride (CC-5013 hydrochloride) is a derivative of Thalidomide and functions as an orally active immunomodulator. It acts through cereblon-mediated selective ubiquitination and degradation of IKZF1 and IKZF3 lymphocyte transcription factors, inhibiting the growth of mature B-cell lymphomas including multiple myeloma, and inducing interleukin-2 (IL-2) release from T cells. Synonyms: Revlimid hydrochloride; CC-5013 hydrochloride; CC5013 hydrochloride; CC 5013 hydrochloride. Grades: >98%. CAS No. 1243329-97-6. Molecular formula: C13H14ClN3O3. Mole weight: 295.72. | |
| Lenalidomide Impurity B | An impurity of Lenalidomide, a medication used for the treatment of myelodysplastic syndrome (MDS), multiple myeloma, and mantle cell lymphoma (MCL). Synonyms: 3-(1,3-Dihydro-4-nitro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(4-Nitro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 4-Nitro Lenalidomide. Grades: > 95%. CAS No. 827026-45-9. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| Letermovir | Letermovir is a novel anti-CMV compound which targets the pUL56 (amino acid 230-370) subunit of the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. It has a novel mode of action targets the enzyme UL56 terminase and keep active to other drug-resistant virus. It has been approved in prophylaxis of CMV infection and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Uses: Antiviral agents. Synonyms: AIC246; AIC-246; AIC 246; MK-8828; MK 8828; MK8828. Grades: ≥98%. CAS No. 917389-32-3. Molecular formula: C29H28F4N4O4. Mole weight: 572.56. | |
| Leukotriene B | Leukotriene B4 is a chemokine with roles in inflammation, immunology, the nervous system, brain and skin. And it also shows antiviral activity towards DNA viruses and retroviruses. Synonyms: Leukotriene B4; LTB4; 5,12-Hete; 5,12-Dihete; (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid. Grades: ≥98%. CAS No. 71160-24-2. Molecular formula: C20H32O4. Mole weight: 336.47. | |
| Leuprolide Acetate | Leuprolide Acetate is a synthetic nonapeptide agonist analog of gonadotropin-releasing hormone (GnRH). Leuprolide Acetate binds to and activates GnRH receptors. Uses: Antineoplastic agents, hormonal. Synonyms: LEUP; A43818; Abbott 43818; TAP144; Leuprorelin; Leuprorelin Acetate; Brand names: ELIGARD; Lupron; Lupron Depot; Leuprorelin acetate; Lupron; Enantone; Leuprolide acetate salt. CAS No. 74381-53-6. Molecular formula: C61H88N16O14. Mole weight: 1269.45. | |
| Levetiracetam Carboxylic Acid | Levetiracetam intermediate. Synonyms: (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetic Acid. Grades: > 95%. CAS No. 102849-49-0. Molecular formula: C8H13NO3. Mole weight: 171.20. | |
| Levetiracetam Impurity A | An impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Synonyms: alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid; Levetiracetam Carboxylic Acid. Grades: > 95%. CAS No. 67118-31-4. Molecular formula: C8H13NO3. Mole weight: 171.20. | |
| Levetiracetam Impurity B | Levetiracetam Impurity B is an impurity of Levetiracetam, a medication indicated for the treatment of epilepsy. Synonyms: (Z)-2-(2-oxopyrrolidin-1-yl)but-2-enamide. Grades: >95%. CAS No. 358629-47-7. Molecular formula: C8H12N2O2. Mole weight: 168.19. | |
| Levetiracetam Impurity D | the enantiomer to Levetiracetam. Synonyms: (αR)-α-Ethyl-2-oxo-1-pyrrolidineacetamide; (R)-Levetiracetam. Grades: > 95%. CAS No. 103765-01-1. Molecular formula: C8H14N2O2. Mole weight: 170.21. | |
| Levobunolol | Levobunolol is a nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma. Uses: A nonselective beta-adrenoceptor antagonist. Synonyms: (S)-5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone. Grades: ≥98%. CAS No. 47141-42-4. Molecular formula: C17H25NO3. Mole weight: 291.388. | |
| Levodopa | Levodopa is used as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells! Keep container tightly closed in a dry and well-ventilated place. Uses: Antiparkinsonism. Synonyms: BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE; HYDROXYTYROSINE; H-PHE(3,4-DI-HYDROXY)-OH; H-PHE(3,4-DI-OH)-OH; H-TYR(3-HYDROXY)-OH; L-BETA-(3,4-DIHYDROXYPHENYL)ALANINE; L-DOPA; L-DOPA, L-3-HYDROXYTYROSINE. Grades: >98%. CAS No. 59-92-7. Molecular formula: C9H11NO4. Mole weight: 197.19. | |
| Levofloxacin-007-S | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Grades: 95%. CAS No. 2130840-90-1. Molecular formula: C20H25FN4O4. Mole weight: 404.43. | |
| Levofloxacin Impurity 8-S | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: Levofloxacin-008-S. CAS No. 2130840-92-3. Molecular formula: C20H24FN3O4. Mole weight: 389.42. | |
| Levofloxacin N-oxide | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (S)-4-(6-carboxy-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-10-yl)-1-methylpiperazine 1-oxide. Grades: > 95%. CAS No. 117678-38-3. Molecular formula: C18H20FN3O5. Mole weight: 377.38. | |
| Levofloxacin Related Compound A | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: N-Desmethyl Levofloxacin ; (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. Grades: > 95%. CAS No. 117707-40-1. Molecular formula: C17H18FN3O4. Mole weight: 347.35. | |
| Levofloxacin Tetrafluoro Impurity 1 | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: (+)-ethyl 2-[[[(S)-1-hydroxyprop-2-yl]amino]methylene]-3-oxo-3-(2,3,4,5-tetrafluorophenyl)propionate. Grades: > 95%. CAS No. 110548-02-2. Molecular formula: C15H15F4NO4. Mole weight: 349.28. | |
| Levofloxacin USP Related Compound E | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: N,N'-Desethylene Levofloxacin Hydrochloride; Levofloxacin EP Impurity G. Grades: 95%. CAS No. 1346603-62-0. Molecular formula: C16H19ClFN3O4. Mole weight: 371.79. | |
| Levonorgestrel butyrate | Levonorgestrel butyrate is a butyl prodrug of levonorgestrel, a widely-used steroidal progestin. Synonyms: 13-ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one butyrate; Levonorgestrel butanoate. CAS No. 86679-33-6. Molecular formula: C25H35O3. Mole weight: 383.54. | |
| Lexanersen | Lexanersen is an abnormal huntingtin synthesis reducer. Synonyms: (P3'S)-2'-O-methyl-P-thioguanylyl-(3'?5')-2'-O-methyluridylyl-(3'?5')-2'-O-methylguanylyl-(3'?5')-2'-O-methylcytidylyl-(3'?5')-(P3'S)-2'-O-methyl-P-thioadenylyl-(3'?5')-(P3'S)-2'-deoxy-P-thiocytidylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'S)-2'-deoxy-P-thiocytidylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioguanylyl-(3'?5')-(P3'S)-P-thiothymidylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'R)-2'-deoxy-P-thioguanylyl-(3'?5')-(P3'S)-2'-deoxy-P-thioadenylyl-(3'?5')-(P3'S)-P-thiothymidylyl-(3'?5')-2'-O-methylguanylyl-(3'?5')-2'-O-methyladenylyl-(3'?5')-2'-O-methylguanylyl-(3'?5')-(P3'S)-2'-O-methyl-P-thioguanylyl-(3'?5')-2'-O-methylguanosine. CAS No. 2073015-40-2. Molecular formula: C206H262N85O112P19S13. Mole weight: 6726.21. | |
| LF 11 | LF 11 is a peptide based on the lipopolysaccharide-binding region of human lactoferricin. It shows antimicrobial activity against gram-negative and gram-positive bacteria. Synonyms: LF 11; LF11; LF-11; L-phenylalanyl-L-glutaminyl-L-tryptophyl-L-glutaminyl-L-arginyl-L-asparagyl-L-isoleucyl-L-arginyl-L-lysyl-L-valyl-L-argininamide. Grades: ≥97% by HPLC. CAS No. 832729-13-2. Molecular formula: C69H112N26O14. Mole weight: 1529.81. | |
| LGB-321 dihydrochloride | This active molecular is a selective ATP-competitive inhibitor of Pan-PIM kinase. LGB-321 is active in PIM2 dependent cell lines that is quite different to other PIM inhibitors reported before. LGB321 inhibits proliferation of a number of cell lines derived from diverse hematological malignancies which is consistent with its activity on all three PIM kinases. LGB321 is efficient in inhibiting tumor xenografts and is well-tolerated within the therapeutic exposure range in animal models. Uses: Anti-tumor. Synonyms: LGB-321 HCl; LGB 321 HCl; LGB321 HCl; N-(4-((3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide dihydrochloride. Grades: 98%. CAS No. 1210416-93-5. Molecular formula: C23H24Cl2F3N5O2. Mole weight: 530.37. | |
| L-Glutamic acid α-tert-butyl ester | L-Glutamic acid α-tert-butyl ester is an ester of L-Glutamic acid used in the synthesis of enantiopure isotopomers of amino acids. Synonyms: L-Glu-OtBu; (S)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid; L-Glutamic acid α-tert butyl ester. Grades: ≥ 98% (HPLC). CAS No. 45120-30-7. Molecular formula: C9H17NO4. Mole weight: 203.20. | |
| L-Glutamine Diethylamide Hydrochloride | Synonyms: (S)-4-Amino-5-(diethylamino)-5-oxopentanoic acid hydrochloride; Pentanoic acid, 4-amino-5-(diethylamino)-5-oxo-, Monohydrochloride, (S). CAS No. 77529-90-9. Molecular formula: C9H19ClN2O3. Mole weight: 238.71. | |
| L-Guanosine | L-Guanosine is a remarkable nucleoside widely utilized in exploring intricate neurological disorders, including Alzheimer's disease and dementia. Furthermore, L-Guanosine's pivotal role in RNA synthesis has propelled its prominence in the realm of antiviral drug development, specifically in the context of studying pernicious RNA viruses, such as hepatitis C. Synonyms: 9-(b-L-Ribofuranosyl)guanine; L-rG; 2-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl-; 2-Amino-9-(β-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one. Grades: ≥97% by HPLC. CAS No. 26578-09-6. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| LH846 | LH846 is a selective inhibitor of CK1δ, which displays no inhibitory activity at CK2. It inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein, showing to lengthen the circadian period in U2OS cells, with minimal effect on amplitude. Synonyms: LH846; LH 846; LH-846. Grades: >98%. CAS No. 639052-78-1. Molecular formula: C16H13ClN2OS. Mole weight: 316.81. | |
| LHF-535 | LHF-535 is an antiviral agent that targets the arenavirus envelope glycoprotein, suggesting its potential use for the treatment of Lassa fever and other fevers caused by arenavirus. Synonyms: HY-112762; 2-[4-[(Z)-2-[1-(4-propan-2-yloxyphenyl)benzimidazol-5-yl]ethenyl]phenyl]propan-2-ol. Grades: 99.20%. CAS No. 1450929-77-7. Molecular formula: C27H28N2O2. Mole weight: 412.52. | |
| LH secretion antagonist 1 | An antagonist of luteinising hormone secretion. Synonyms: 2,6-Methano-3-benzazocine-6,8(1H)-diol, 3-(3-butyn-1-yl)-2,3,4,5-tetrahydro-11,11-dimethyl-, hydrochloride. CAS No. 88531-67-3. Molecular formula: C18H24ClNO2. Mole weight: 321.84. | |
| LHW090-A7 sodium | LHW090-A7 is an inhibitor of neutral endopeptidase (NEP), an enzyme responsible for the metabolic inactivation of enkephalins. It has been shown to induce the increase of plasma levels of endogenous atrial natriuretic peptides (NPs). Synonyms: (S)-3-(3'-Chloro-[1,1'-biphenyl]-4-yl)-2-(((S)-1-ethoxy-1-oxopropan-2-yl)amino)propanoic sodium salt. Grades: ≥98%. Molecular formula: C20H21ClNO4·Na. Mole weight: 397.8. | |
| Licarin A | Cas No. 51020-86-1. | |
| Liensinine | Liensinine is extracted from the plantule of Nelumbo nucifera Gaertn. It is a kind of isoquinoline alkaloid, and it can antagonize the ventricular arrhythmias. Synonyms: Hiensinine; 2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]-; Phenol,4-[[(1R)-1,2,3,4-tetrahydro-6, 7-dimethoxy-; 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol; 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]phenol. Grades: >98%. CAS No. 2586-96-1. Molecular formula: C37H42N2O6. Mole weight: 610.739. | |
| Liensinine diperchlorate | Liensinine diperchlorate can be extracted from the plantule of Nelumbo nucifera Gaertn. Synonyms: Liensinine diperchlorate; Liensinine (Diperchlorate); 5088-90-4; 4-[[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol; perchloric acid; HY-N0485; s9424; CCG-270503; MS-31504; CS-0009004. Grades: >98%. CAS No. 5088-90-4. Molecular formula: C37H42N2O6.(HClO4)2. Mole weight: 811.67. | |
| Liensinine perchlorate | Liensinine Perchlorate is extracted from the plantule of Nelumbo nucifera Gaertn. Synonyms: 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]phenol perchlorate. Grades: >98%. CAS No. 2385-63-9. Molecular formula: C37H42N2O6.ClHO4. Mole weight: 711.2. | |
| Lificiguat | Lificiguat, also known as YC-1, is a inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). YC-1 is widely used as a potent inhibitor of HIF-1alpha both in vitro and in vivo, and is also being developed as a novel anticancer drug. YC-1 effectively inhibits tumor invasion and metastasis, and imply that YC-1 is worth while to further develop as a multipurpose anticancer drug. Uses: Platelet aggregation inhibitors. Synonyms: YC-1; YC 1; YC1. Grades: 0.98. CAS No. 170632-47-0. Molecular formula: C19H16N2O2. Mole weight: 304.34. | |
| Ligustrazine Hydrochloride | Ligustrazine Hydrochloride has certain protection effect on the vascular endothelium undergoing CPB, and lower excessive activation of coagulation reaction and inflammation reaction in patients undergoing CPB. Uses: Increased coronary flow. Synonyms: LIGUSTRAZOINEHYDROCHLORIDE; 2,3,5,6-Tetramethylpyrazine hydrochloride; Chuanxiongzine Hydrochlorid; Chuanxiongzine Hydrochloride, TetraMethylpyrazine hydrochloride. Grades: >98%. CAS No. 76494-51-4. Molecular formula: C8H12N2.HCl. Mole weight: 208.69. | |
| LIMK1 inhibitor BMS 4 | LIMK1 inhibitor BMS 4 is a potent LIM kinase 1 (LIMK1; IC50 = 22nM) inhibitor devoid of any cytotoxic side effects. Synonyms: 1-ethyl-3-[5-[6-(4-methoxy-2,6-dimethylphenyl)-2-pyrazin-2-ylpyrimidin-4-yl]-1,3-thiazol-2-yl]urea. Grades: 99%. CAS No. 905298-84-2. Molecular formula: C23H23N7O2S. Mole weight: 461.54. | |
| Linaclotide acetate | Linaclotide is an oligo-peptide agonist of guanylate cyclase 2C. It can be used for the treatment in adults of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation. Uses: Constipation; irritable bowel syndrome. Synonyms: L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide), acetate (1:1); L-Tyrosine, L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide), monoacetate (salt); Linaclotide monoacetate; MM 416775; H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH.CH3CO2H (Disulfide bridge: Cys1-Cys6, Cys2-Cys10, Cys5-Cys13). Grades: 95%. CAS No. 851199-60-5. Molecular formula: C61H83N15O23S6. Mole weight: 1586.80. | |
| Linezolid Impurity 42 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Synonyms: 2-amino-3-chloropropan-1-ol; Linezolid Impurity 42; 725676-93-7; AKOS006352833. Grades: 95%. CAS No. 725676-93-7. Molecular formula: C3H8ClNO. Mole weight: 109.55. | |
| Linezolid Impurity 44 | An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Synonyms: N-[(2S)oxiranylmethyl]acetamide; Acetamide, N-[(2S)-oxiranylmethyl]-; N-[[(2S)-oxiran-2-yl]methyl]acetamide; (S)-(+)-N-(oxiranylMethyl)acetaMide; (S)-N-oxiranylmethyl-acetamide; SCHEMBL2863034; (s)-n-(oxiranylmethyl)acetamide; DTXSID80453297; HBTVZPMDLRPWKZ-YFKPBYRVSA-N; N-[(2S)oxiranylmethyl] acetamide; (S)-N-(Oxiran-2-ylmethyl)acetamide; CS-0166034; (S)-N-(oxiran-2-ylmethyl)acetamide? (Brexpiprazole Impurity pound(c). Grades: 95%. CAS No. 183805-10-9. Molecular formula: C5H9NO2. Mole weight: 115.13. | |
| Linezolid Impurity PNU140155 | N-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]acetamide is an impurity of Linezolid. Synonyms: N-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]acetamide. Grades: > 95%. CAS No. 333753-67-6. Molecular formula: C15H22FN3O3. Mole weight: 311.35. | |
| Linezolid N-Oxide | Linezolid N-oxide is a derivative of Linezolid, an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant. Linezolid works by inhibiting bacterial protein synthesis. Synonyms: (S)-4-{4-[5-(Acetamidomethyl)-2-oxooxazolidin-3-yl]-2-fluorophenyl}morpholine 4-oxide; N-[[(5S)-3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; (S)-N-[[3-[3-Fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Acetamide, N-[[3-[3-fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-; N-[[(5S)-3-[3-Fluoro-4-(4-oxido-4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide. Grades: ≥95%. CAS No. 189038-36-6. Molecular formula: C16H20FN3O5. Mole weight: 353.35. | |
| Lipid ALC-0315 | ALC-0315 can be used to form lipid nanoparticle (LNP, non-viral gene delivery system). Synonyms: ALC-0315; ((4-Hydroxybutyl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate). Grades: >98%. CAS No. 2036272-55-4. Molecular formula: C48H95NO5. Mole weight: 766.27. | |
| Lipid peroxidation inhibitor 1 | A lipid peroxidation inhibitor (IC50= 0.07 μM). Synonyms: 5-Benzofuranamine, 2,3-dihydro-2,4,6,7-tetramethyl-2-[(4-phenyl-1-piperidinyl)methyl]-. CAS No. 142873-41-4. Molecular formula: C24H32N2O. Mole weight: 364.52. | |
| Liproxstatin-1 hydrochloride | Liproxstatin-1 is a potent inhibitor of ferroptosis, a form of regulated necrosis associated with the iron-dependent accumulation of lipid hydroperoxides. Synonyms: N-[(3-Chlorophenyl)methyl]spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 2250025-95-5. Molecular formula: C19H21ClN4·HCl. Mole weight: 377.31. | |
| Lisinopril Impurity D | An impurity of ACE inhibitor Lisinopril, which is indicated for the treatment of high blood pressure and heart failure. Synonyms: Lisinopril (S,S,R)-Diketopiperazine; (2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-phenylbutanoic acid. Grades: > 95%. CAS No. 219677-82-4. Molecular formula: C21H29N3O4. Mole weight: 387.47. | |
| Lisinopril Impurity F | Lisinopril Impurity F is an impurity of Lisinopril, a medication of the angiotensin-converting enzyme inhibitor class that is used to treat high blood pressure. Synonyms: Lisinopril Cyclohexyl Analogue; (2S) -1- [ (2S) -6-Amino-2- [ [ (1S) -1-carboxy-3-cyclohexylpropyl] amino] hexanoyl] pyrrolidine-2-carboxylic acid. Grades: > 95%. CAS No. 1132650-67-9. Molecular formula: C21H37N3O5. Mole weight: 411.54. | |
| LIT-927 | LIT-927 is an orally available neutraligand of CXCL12. It reduces eosinophil recruitment in a murine model of allergic airway hypereosinophilia, displaying anti-inflammatory effects. Synonyms: 4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one. CAS No. 2172879-52-4. Molecular formula: C17H13ClN2O3. Mole weight: 328.75. | |
| Lithium orotate | Lithium orotate (CAS# 5266-20-6 ) is a useful research chemical. Synonyms: 2,4-dioxo-1H-pyrimidine-6-carboxylate lithium salt. CAS No. 5266-20-6. Molecular formula: C5H3LiN2O4. Mole weight: 162.10. | |
| Lithospermic acid | Lithospermic acid is extracted from the roots of Lithospermum ruderale. It is Cardiotonic agent. It possesses anti-HIV activity. Synonyms: 4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid; Aids071478; Aids-071478; Clinopodic acid H. Grades: >98%. CAS No. 28831-65-4. Molecular formula: C27H22O12. Mole weight: 538.5. | |
| Lixadesiran | Lixadesiran is a cyclooxygenase synthesis reducer, with antineoplastic activity. Synonyms: guanylyl- (3'?5')-guanylyl- (3'?5')-uridylyl- (3'?5')-cytidylyl- (3'?5')-uridylyl- (3'?5')-guanylyl- (3'?5')-guanylyl- (3'?5')-uridylyl- (3'?5')-guanylyl- (3'?5')-cytidylyl- (3'?5')-cytidylyl- (3'?5')-uridylyl- (3'?5')-guanylyl- (3'?5')-guanylyl- (3'?5')-uridylyl- (3'?5')-cytidylyl- (3'?5')-uridylyl- (3'?5')-guanylyl- (3'?5')-adenylyl- (3'?5')-uridylyl- (3'?5')-guanylyl- (3'?5')-adenylyl- (3'?5')-uridylyl- (3'?5')-guanylyl- (3'?5')-uridine, duplex with cytidylyl- (5'?3')-cytidylyl- (5'?3')-adenylyl- (5'?3')-guanylyl- (5'?3')-adenylyl- (5'?3')-cytidylyl- (5'?3')-cytidylyl- (5'?3')-adenylyl- (5'?3')-cytidylyl- (5'?3')-guanylyl- (5'?3')-guanylyl- (5'?3')-adenylyl- (5'?3')-cytidylyl- (5'?3')-cytidylyl- (5'?3')-adenylyl- (5'?3')-guanylyl- (5'?3')-adenylyl- (5'?3')-cytidylyl- (5'?3')-uridylyl- (5'?3')-adenylyl- (5'?3')-cytidylyl- (5'?3')-uridylyl- (5'?3')-adenylyl- (5'?3')-cytidylyl- (5'?3')-adenosine. CAS No. 1152798-49-6. Molecular formula: C475H591N189O346P48. Mole weight: 15970.72. | |
| LJH685 | LJH685, binding to the RSK2 N-terminal kinase ATP-binding site, is a potent inhibitor that specificlly targets RSK with antiproliferative effects in MAPK pathway-dependent cancer cell lines only in anchorage-independent growth setting. in vitro: efficient. Synonyms: LJH685; LJH 685; LJH-685; NVP-LJH685; NVP LJH685; NVPLJH685; NVP-LJH-685; NVP LJH 685; 2,6-difluoro-4-[4-[4-(4-methylpiperazin-1-yl)phenyl]pyridin-3-yl]phenol; CHEMBL3604793; CS-5524; HY-19712; CS 5524; HY 19712; CS5524; HY19712; 2,6-Difluoro-4-{4-[4-(4-Methylpiperazin-1-Yl)phenyl]pyridin-3-Yl}phenol 2NK. CAS No. 1627710-50-2. Molecular formula: C22H21F2N3O. Mole weight: 381.42. | |
| LJI308 | LJI308 is a RSK inhibitor. LJI308 overcomes chemoresistance by eliminating cancer stem cells. LJI308 targets the CSC population and repress TNBC growth and dissemination. Synonyms: LJI308; LJI-308; LJI 308; NVP-LJI308; NVP-LJI-308; NVP-LJI 308. Grades: 98%. CAS No. 1627709-94-7. Molecular formula: C21H18F2N2O2. Mole weight: 368.38. | |
| LJP 1586 | LJP 1586, under the IUPAC name Benzenepropanamine, β-(fluoromethylene)?-4-methoxy-, hydrochloride (1:1)?, (βZ)?-, a selective vascular adhesion protein (VAP-1) blocker that has been shown to be beneficial against transient forebrain ischemia and transient middle cerebral artery occlusion(MCAo) and to prevent leukocyte adhesion and parenchymal infiltration and improve sneurologic status after SAH. Uses: Treat human stroke or other neuropathy?/nervous system disorder; a selective vascular adhesion protein (vap-1) blocker; anti-inflammatory. Synonyms: LJP 1586; LJP1586; LJP-1586; Benzenepropanamine, β-(fluoromethylene)?-4-methoxy-, hydrochloride (1:1)?, (βZ)?-; (Z)-3-fluoro-2-(4-Methoxybenzyl)allylamine. CAS No. 955037-42-0. Molecular formula: C11H15ClFNO. Mole weight: 231.69. | |
| LLY-283 | LLY-283 is an inhibitor of protein arginine methyltransferase 5 (PRMT5) with antitumor activity. It potently suppresses cancer growth via inhibiting PRMT5 expressed in breast cancer, gastric cancer, glioblastoma, and lymphoma cells. Synonyms: 2-(4-Aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[hydroxy(phenyl)methyl]oxolane-3,4-diol. Grades: ≥98%. CAS No. 2040291-27-6. Molecular formula: C17H18N4O4. Mole weight: 342.4. | |
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