BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Necrostatin 2 racemate | Necrostatin 2 racemate is the racemate of Necrostatin, which is a potent necroptosis inhibitor. Grades: >98%. CAS No. 852391-15-2. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. |  |
| Necrostatin 2 S enantiomer | Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin, which is a potent necroptosis inhibitor. Synonyms: Necrostatin 2 S enantiomer; 852391-20-9; Necrostatin 2 (S enantiomer); Necrostatin 2 S-Enantiomer; (5S)-5-[(7-CHLORO-1H-INDOL-3-YL)METHYL]-3-METHYLIMIDAZOLIDINE-2,4-DIONE; (S)-5-((7-chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione; SCHEMBL859928; CHEMBL365607; CJB39120; HY-14622B; AKOS030526930; CS-1665; 2,4-Imidazolidinedione, 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-, (5S)-; NCGC00390744-01; MS-23944; F84976; A917559. Grades: >98%. CAS No. 852391-20-9. Molecular formula: C13H12ClN3O2. Mole weight: 277.71. | |
| Necrostatin-5 | Necrostatin-5 is a selective allosteric inhibitor of RIP1 kinase, an enzyme responsible for necroptosis. Synonyms: Nec-5; 2-[[3,4,5,6,7,8-hexahydro-3-(4-methoxyphenyl)-4-oxo[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]-acetonitrile; 3-p-methoxyphenyl-5,6-tetramethylenothieno[2,3-d]pyrimidin-4-one-2-mercaptoethylcyanide. Grades: ≥98%. CAS No. 337349-54-9. Molecular formula: C19H17N3O2S2. Mole weight: 383.5. | |
| Necrosulfonamide | Necrosulfonamide is a pharmacological inhibitor of MLKL with IC50 values of 124 nM in human HT-29, which significantly decreases BV6/DAC-induced cell death in MV4-11 cells. It prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Synonyms: (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide. Grades: ≥98% by HPLC. CAS No. 1360614-48-7. Molecular formula: C18H15N5O6S2. Mole weight: 461.47. | |
| Nedaplatin | Nedaplatin is a derivative of cisplatin and DNA damage agent for tumor colony forming units with IC50 of 94 μM. Synonyms: Nedaplatin; 95734-82-0; AquplaNSC 375101Dazane;2-hydroxyacetic acid;platinum. Grades: >98%. CAS No. 95734-82-0. Molecular formula: C2H8N2O3Pt. Mole weight: 303.17. | |
| Nedocromil | Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma. Synonyms: FPL59002; FPL-59002; FPL 59002; Nedocromil; Nedocromilo. Grades: >98%. CAS No. 69049-73-6. Molecular formula: C19H17NO7. Mole weight: 371.34. | |
| Nedocromil sodium | Nedocromil sodium is a mast cell stabilizer that prevents wheezing, shortness of breath, and other breathing problems caused by asthma. Synonyms: 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, sodium salt (1:2); 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic Acid Disodium Salt; Alocril; FPL 59002KP; Nedocromil disodium salt; Rapitil; Tayled; Tilade; Tilarin; 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt. Grades: 95%. CAS No. 69049-74-7. Molecular formula: C19H15NNa2O7. Mole weight: 415.30. | |
| Neferine | Neferine is a bis-benzylisoquinoline alkaloid isolated from the green seed embryos Nelumbo Nucifera Gaertn (Lotus) that displays multiple pharmacological activities including anti-tumor, antidepressant-like and antiarrhythmic actions. It potently inhibits proliferation of human osteosarcoma cells while is low-toxic on non-neoplastic human osteoblast cells. It inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. Synonyms: 4-[(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)methyl]-2-[[1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methylisoquinolin-7-yl]oxy]phenol; 4''-O-Methylliensinine; Methylliensinine; Phenol,4-[[(1S)-1,2,3,4-tetrahydro-6,7-diMethoxy-2-Methyl-1-isoquinolinyl]Methyl]-2-[[(1R)-1,2,3,4-tetrahydro-6-Methoxy-1-[(4-Methoxyphenyl)Methyl]-2-Methyl-7-isoquinolinyl]oxy]-; 4-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]phenol. Grades: >98%. CAS No. 2292-16-2. Molecular formula: C38H44N2O6. Mole weight: 624.76. | |
| Negletein | Negletein is a flavonoid with anti-inflammatory and immunomodulatory activities. Synonyms: 5,6-Dihydroxy-7-methoxyflavone; Baicalein-7-methylether; 7-O-Methylbaicalein. Grades: >98%. CAS No. 29550-13-8. Molecular formula: C16H12O5. Mole weight: 284.26. | |
| Neoastilbin | Neoastilbin is a compound of the flavonoid class found in the Simlax glabra Roxb. Synonyms: (2S,3S)-Taxifolin 3-rhamnoside; (2S,3S)-dihydroquercetin 3-O-alpha-L-rhamnoside; (2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside. Grades: >98%. CAS No. 54081-47-9. Molecular formula: C21H22O11. Mole weight: 450.396. | |
| Neoeriocitrin | Neoeriocitrin is a flavonoid with antioxidant capacity. Synonyms: eriodictyol-7-neohesperidoside; Eriodictyol 7-neohesperidoside; Eriodictyol 7-O-neohesperidoside. Grades: 98%. CAS No. 13241-32-2. Molecular formula: C27H32O15. Mole weight: 596.5. | |
| Neoisoastilbin | Neoisoastilbin is a compound of the flavonoid class found in the Simlax glabra Roxb. Synonyms: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2,3-dihydrochromen-4-one. Grades: >98%. CAS No. 54141-72-9. Molecular formula: C21H22O11. Mole weight: 450.4. | |
| Neostigmine Bromide | Neostigmine bromide(Prostigmin) is a reversible acetylcholinesterase inhibitor and a parasympatho-mimetic. Grades: >98%. CAS No. 114-80-7. Molecular formula: C12H19N2O2.Br. Mole weight: 303.2. | |
| Nepafenac | Nepafenac is an inhibitor of COX-1 and COX-2. Synonyms: AL 6515; AL6515; AL-6515; AHR 9434; AHR9434; AHR-9434; Nevanac; Nepafenac; Nevanac. 2-(2-amino-3-benzoylphenyl)acetamide. CAS No. 78281-72-8. Molecular formula: C15H14N2O2. Mole weight: 254.28. | |
| Nepicastat HCl | Nepicastat hydrochloride (SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase that catalyzes the conversion of dopamine to norepinephrine. Nepicastat hydrochloride shows the selective and concentration-dependent inhibition effects on bovine and human dopamine-beta-hydroxylase activity in vitro. In vivo, Nepicastat hydrochloride increases dopamine content and dopamine/noradrenaline ratio in a dose-dependent manner. Nepicastat hydrochloride also produces the similar effects on noradrenaline, dopamine and dopamine/noradrenaline ratio in tissues and plasma of beagle dogs. Nepicastat is currently in Phase II clinical trials in patients with Posttraumatic Stress Disorder. Uses: Nepicastat is currently in phase ii clinical trials in patients with posttraumatic stress disorder. Synonyms: N6022; N 6022; N-6022; Nepicastat hydrochloride; (S)-5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1H-imidazole-2(3H)-thione hydrochloride; Nepicastat (hydrochloride); UNII-3WK068D17I. Grades: >98%. CAS No. 170151-24-3. Molecular formula: C14H16ClF2N3S. Mole weight: 331.81. | |
| Nε-Palmitoyl-L-glutamic Acid γ-Succinimidyl-α-tert-butyl Ester | Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. Synonyms: Palm-glu(nhs)-otbu; L-Glutamic acid, N-(1-oxohexadecyl)-, 1-(1,1-dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) ester; (S)-1-tert-butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-palmitamidopentanedioate; Pal-L-Glu(OSu)-OtBu; N-Palmitoyl-L-glutamic Acid 1-tert-Butyl 5-(N-Succinimidyl) Ester; 1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) N-hexadecanoyl-L-glutamate. CAS No. 204521-63-1. Molecular formula: C29H50N2O7. Mole weight: 538.70. | |
| Neridronate | Neridronic acid is a Bone resorption factor inhibitor and it can be used to treat Osteogenesis imperfecta and Paget's disease of bone. Uses: Osteogenesis imperfecta;paget's disease of bone. Synonyms: Neridronate; Neridronic acid; Nerixia;(6-Amino-1-hydroxyhexylidene)diphosphonic acid;80729-79-9(Sodium salt). Grades: 97%. CAS No. 79778-41-9. Molecular formula: C6H17NO7P2. Mole weight: 277.15. | |
| Nesiritide Acetate | A brain natriuretic peptide secreted by the human heart in response to cardiac volume or pressure. Synonyms: L-Histidine, L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminylglycyl-L-serylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-arginyl-L-lysyl-L-methionyl-L-α-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-, cyclic (10?26)-disulfide, acetate (1:1); H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH.CH3CO2H (Disulfide bridge: Cys10-Cys26); Brain natriuretic peptide-32 (human) acetate; Brain natriuretic peptide (1-32) (human) acetate; BNP 32 acetate; Human brain natriuretic factor-32 acetate. Grades: ≥98%. CAS No. 1684439-46-0. Molecular formula: C143H244N50O42S4.C2H4O2. Mole weight: 3524.10. | |
| Netarsudil hydrochloride | Netarsudil is a ROCK inhibitor and is approved for the treatment of glaucoma. Synonyms: AR-13324 hydrochloride; Netarsudil dihydrochloride; [4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate dihydrochloride. Grades: >98%. CAS No. 1253952-02-1. Molecular formula: C28H29Cl2N3O3. Mole weight: 526.458. | |
| N-Ethylmaleimide | N-Ethylmaleimide (NEM) is a derivative of maleic acid and is used as a reagent for alkylation and covalent modification of nucleophilic thiol residues on proteins. It acts as an irreversible inhibitor of all cysteine peptidases that alkylates the active site thiol group of the enzymes. Uses: Used in cancer research; a sulfhydryl reagent that is widely used in experimental biochemical studies. Synonyms: NEM; 1-Ethyl-1H-pyrrole-2,5-dione; ethylmaleimide. Grades: >98.0%(HPLC)(N). CAS No. 128-53-0. Molecular formula: C6H7NO2. Mole weight: 125.13. | |
| N-Ethyl-o-crotonotoluidide | Cas No. 483-63-6. | |
| N-ethyltoluene-2-sulphonamide | N-ethyltoluene-2-sulphonamide (CAS# 1077-56-1 ) is a useful research chemical. Synonyms: N-ethyl-o-toluenesulfonamide; RIT-CIZER NO 8; N-E-O/PTSA. Grades: 95 %. CAS No. 1077-56-1. Molecular formula: C9H13NO2S. Mole weight: 199.27. | |
| Neurokinin A (4-10) | Neurokinin A (4-10), an endogenous neuromodulatory peptide formerly known as substance K, is an atachykinin NK2 receptor agonist. Synonyms: H-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2; L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-valyl-glycyl-L-leucyl-L-methioninamide; (5S,8S,14S,17S,20S,23S)-23-amino-17-benzyl-5-carbamoyl-20-(hydroxymethyl)-8-isobutyl-14-isopropyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid. Grades: 98%. CAS No. 97559-35-8. Molecular formula: C34H54N8O10S. Mole weight: 766.91. | |
| Neuromedin S (rat) | Neuromedin S, a novel neuropeptide of 36 amino acids isolated from rat brain as an endogenous ligand for the orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, is a potent, endogenous neuromedin U receptor agonist (EC50 values are 65 and 91 pM at NMU1 and NMU2 respectively). Central NMS may exert a physiological antidiuretic action via vasopressin release. Synonyms: L-leucyl-L-prolyl-L-arginyl-L-leucyl-L-leucyl-L-histidyl-L-threonyl-L-α-aspartyl-L-seryl-L-arginyl-L-methionyl-L-alanyl-L-threonyl-L-isoleucyl-L-α-aspartyl-L-phenylalanyl-L-prolyl-L-lysyl-L-lysyl-L-α-aspartyl-L-prolyl-L-threonyl-L-threonyl-L-seryl-L-leucylglycyl-L-arginyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide, trifluoroacetate salt; Leu-Pro-Arg-Leu-Leu-His-Thr-Asp-Ser-Arg-Met-Ala-Thr-Ile-Asp-Phe-Pro-Lys-Lys-Asp-Pro-Thr-Thr-Ser-Leu-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. CAS No. 843782-19-4. Molecular formula: C193H307N57O49S. Mole weight: 4241.97. | |
| Neuromedin U-25 (human) | Neuromedin U-25 (NMU-25) is a 25-amino acid neuropeptide found in CNS of humans, demonstrated to drive smooth muscle contraction and regulate blood pressure. In vivo study has shown that it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. Synonyms: NMU-25 (human); H-Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2; L-Aspartamide, L-phenylalanyl-L-arginyl-L-valyl-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-. Grades: ≥98%. CAS No. 312306-89-1. Molecular formula: C141H203N41O38. Mole weight: 3080.37. | |
| Neuropeptide S (human) | Neuropeptide S (human), one of the "youngest" members among the biologically active peptides, is a potent endogenous neuropeptide S receptor agonist (EC50 = 9.4 nM), which modulates arousal, wakefulness, anxiety, fear-extinction, and fear memory consolidation. Synonyms: NPS (human); H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Thr-Gly-Met-Lys-Lys-Thr-Ser-Phe-Gln-Arg-Ala-Lys-Ser-OH; L-seryl-L-phenylalanyl-L-arginyl-L-asparagyl-glycyl-L-valyl-glycyl-L-threonyl-glycyl-L-methionyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-L-serine. Grades: ≥95%. CAS No. 412938-67-1. Molecular formula: C93H155N31O28S. Mole weight: 2187.48. | |
| Neuropeptide S (Rat) | Neuropeptide S, a neuropeptide that plays a major role in regulating sleep and stress, is a potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM for inducing intracellular calcium mobilization in HEK293 cells expressing the human receptor). It enhances memory during the consolidation phase and interacts with noradrenergic systems in the brain. Synonyms: NPS (rat); H-Ser-Phe-Arg-Asn-Gly-Val-Gly-Ser-Gly-Val-Lys-Lys-Thr-Ser-Phe-Arg-Arg-Ala-Lys-Gln-OH; L-seryl-L-phenylalanyl-L-arginyl-L-asparaginylglycyl-L-valylglycyl-L-serylglycyl-L-valyl-L-lysyl-L-lysyl-L-threonyl-L-seryl-L-phenylalanyl-L-arginyl-L-arginyl-L-alanyl-L-lysyl-L-glutamine. Grades: ≥95%. CAS No. 412938-75-1. Molecular formula: C95H160N34O27. Mole weight: 2210.52. | |
| Neuropeptide Y (29-64) | Neuropeptide Y is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. Synonyms: Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr; L-tyrosyl-L-prolyl-L-seryl-L-lysyl-L-prolyl-L-alpha-aspartyl-L-asparagyl-L-prolyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alanyl-L-prolyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-histidyl-L-tyrosyl-L-isoleucyl-L-asparagyl-L-leucyl-L-isoleucyl-L-threonyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosine. Grades: ≥95%. CAS No. 303052-45-1. Molecular formula: C189H284N54O58S. Mole weight: 4272.66. | |
| Neurotensin (8-13) | Neurotensin (8-13), the smallest active fragment of neurotensin, results in a decrease in cell-surface NT1 receptors (NTR1) density. Synonyms: H-Arg-Arg-Pro-Tyr-Ile-Leu-OH; L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; NT(8-13); Neurotensin Fragment 8-13; N5-(Diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine. Grades: >97% by HPLC. CAS No. 60482-95-3. Molecular formula: C38H64N12O8. Mole weight: 816.99. | |
| Neurotensin (cattle) | Neurotensin, a gut tridecapeptide with many central and peripheral functions, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinityneurotensin receptors(NTR). Neurotensin also can be used as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Synonyms: H-Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH; L-pyroglutamyl-L-leucyl-L-tyrosyl-L-alpha-glutamyl-L-asparagyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; Neurotensin 1-13; Neurotensin (ox); 5-Oxo-L-prolyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine; L-Leucine, 5-oxo-L-prolyl-L-leucyl-L-tyrosyl-L-α-glutamyl-L-asparaginyl-L-lysyl-L-prolyl-L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-; Bovine neurotensin; Canine neurotensin; Mouse neurotensin; Neurotensin (bovine hypothalamus); Neurotensin (dog); Neurotensin (rat); Ox neurotensin. Grades: ≥97% by HPLC. CAS No. 55508-42-4. Molecular formula: C78H121N21O20. Mole weight: 1672.92. | |
| Nexinhib20 | Nexinhib20 is a Rab27 inhibitor (IC50 = 330 nM) that selectively inhibits neutrophil exocytosis. It suppresses extracellular production of superoxide anion and expression of cytochrome b in plasma membrane. Synonyms: Neutrophil exocytosis inhibitor 20; 4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one. Grades: ≥98% by HPLC. CAS No. 331949-35-0. Molecular formula: C15H16N4O3. Mole weight: 300.31. | |
| NF 1819 | NF 1819 is a selective irreversible β-lactam-based monoacylglycerol lipase inhibitor with IC50 values of 0.25 and 7.4 nM at rMAGL and hMAGL. Synonyms: NF-1819; NF 1819; NF1819; (3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone. Grades: ≥98% by HPLC. CAS No. 1881244-28-5. Molecular formula: C24H22FN5O4. Mole weight: 463.46. | |
| N-Fluorobenzenesulfonimide | N-Fluorobenzenesulfonimide (CAS# 133745-75-2) is a mild electrophilic fluorinating reagent. Synonyms: N-(benzenesulfonyl)-N-fluorobenzenesulfonamide. Grades: 95 %. CAS No. 133745-75-2. Molecular formula: C12H10FNO4S2. Mole weight: 315.34. | |
| N-(Formyl amidino)-N-β-D-ribofuranosylurea | N-(Formyl amidino)-N-β-D-ribofuranosylurea is a formidable antiviral compound extensively applied in the biomedical sector, exhibiting exceptional qualities in the research of impeding the proliferation of designated viruses like influenza and herpes viruses. Grades: > 95%. CAS No. 65126-88-7. Molecular formula: C8H14N4O6. Mole weight: 262.22. | |
| N-Formyl Apixaban | N-Formyl Apixaban is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: N-formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; 1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, N-formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-. CAS No. 1351611-14-7. Molecular formula: C26H25N5O5. Mole weight: 487.5. | |
| N-Formyl Desloratadine | Cas No. 117810-61-4. | |
| NG25 | Type II inhibitor of TAK1 (MAP3K7) and MAP4K2 (GCK) with nanomolar potency for a wider range of kinases (IC50 values 13 nM, 22 nM, 56 nM, 75 nM, 82 nM, 102 nM, 113 nM, and 149 nM for LYN, MAP4K2, CSK, Abl, FER, p38α, SRC, and TAK1, repectively). At 0.1 μM NG25 shows strong inhibition of TAK1, Lck, MAP4K2, p38α, Abl, YES1, and OSR1. NG 25 potently inhibited the activation of IKKβ by TLR7 and TLR9 agonists and prevented the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells. Synonyms: NG 25; NG-25. Grades: >98%. CAS No. 1315355-93-1. Molecular formula: C29H30F3N5O2. Mole weight: 537.58. | |
| NG 25 trihydrochloride | NG 25 trihydrochloride is a type II inhibitor of TAK1 (MAP3K7) and MAP4K2 (GCK) with nanomolar potency for multiple kinases including TAK1, Lck, MAP4K2, p38α, Abl, YES1, and OSR1. NG 25 potently inhibits the activation of IKKβ by TLR7 and TLR9 agonists, and prevents the secretion of type 1 IFNs induced by these ligands in Gen2.2 cells. Synonyms: NG 25 trihydrochloride; NG25 trihydrochloride; NG-25 trihydrochloride. Grades: 98%. CAS No. 2108554-00-1. Molecular formula: C29H30F3N5O2.3HCl. Mole weight: 646.96. | |
| N-(gamma-Glutamyl)ethanolamine | N-(gamma-Glutamyl)ethanolamine is a derivative of glutamine. Synonyms: N-(γ-L-glutamyl)ethanolamine. CAS No. 2650-74-0. Molecular formula: C7H14N2O4. Mole weight: 190.20. | |
| NGI 1 | NGI 1 is a cell-permeable oligosaccharyltransferase (OST) inhibitor. It exhibits a potent activity against flaviviruses via blocking viral RNA replication. It also selectively arrests proliferation of non-small-cell lung cancer cells that are dependent on EGFR or FGFR for survival. Synonyms: NGI-1; NGI1; ML414; ML 414; ML-414; 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide. Grades: ≥98% by HPLC. CAS No. 790702-57-7. Molecular formula: C17H22N4O3S2. Mole weight: 394.51. | |
| N-Glycolylneuraminic acid | N-Glycolylneuraminic acid is a derivative of sialic acid. Synonyms: Neu5Gc; N-(2-Hydroxyacetyl)neuraminic Acid; 3,5-Dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-D-galacto-2-nonulosonic Acid; Glycolylneuraminic Acid; N-Glycolyl Neuraminic Acid; N-glycoloyl-beta-neuraminic acid. Grades: ≥95%. CAS No. 1113-83-3. Molecular formula: C11H19NO10. Mole weight: 325.27. | |
| NGP-555 | NGP-555 is a γ-secretase modulator that significantly lowers Aβ42 in cell cultures (9 nM) while increasing shorter forms of A&beta. NGP-555 has the potential for the treatment of Alzheimer's disease. Uses: Potential treatment of alzheimer's disease. Synonyms: NGP-555; NGP 555; NGP555. N-(5-ethyl-2,4-dimethylphenyl)-4-[3-fluoro-4-(4-methylimidazol-1-yl)phenyl]-1,3-thiazol-2-amine. Grades: > 98%. CAS No. 1304630-27-0. Molecular formula: C23H23FN4S. Mole weight: 406.523. | |
| n-Heptyl acrylate | Synonyms: 2-Propenoic acid, heptyl ester; Acrylic acid, heptyl ester; ENT 15748; Heptyl acrylate; heptylacrylate. CAS No. 2499-58-3. Molecular formula: C10H18O2. Mole weight: 170.25. | |
| N-Hexadecylpropane-1,3-diamine | N-Hexadecylpropane-1,3-diamine is a useful research chemical. Synonyms: N1-Hexadecyl-1,3-propanediamine; Cetylaminopropylamine. CAS No. 7173-60-6. Molecular formula: C19H42N2. Mole weight: 298.55. | |
| n-Hexylphosphonic acid | n-Hexylphosphonic acid (CAS# 4721-24-8 ) is a useful research chemical. Synonyms: LABOTEST-BB LT00408920. Grades: 98 %. CAS No. 4721-24-8. Molecular formula: C6H15O3P. Mole weight: 166.16. | |
| NHI 2 | NHI-2 is a lactate dehydrogenase isoform inhibitor with IC50 value of 14.7 μM. It has anti-glycolytic activity against a variety of cancer cells. Synonyms: NHI-2; NHI 2; NHI2; Methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate. Grades: ≥98% by HPLC. CAS No. 1269802-97-2. Molecular formula: C17H12F3NO3. Mole weight: 335.28. | |
| N-hydroxypipecolic acid | N-Hydroxypipecolic acid, a pivotal biochemical component of drug synthesis for treatment of Alzheimer's and other neurodegenerative diseases, remarkably inhibits gamma-secretase enzyme leading to decreased amyloid beta production, a hallmark of Alzheimer's. Synonyms: 1-hydroxy-2-piperidinecarboxylic acid; 2-Piperidinecarboxylic acid, 1-hydroxy-; hydroxypipecolic acid. Grades: 95%. CAS No. 115819-92-6. Molecular formula: C6H11NO3. Mole weight: 145.16. | |
| N-Hydroxysulfosuccinimide sodium | N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Sulfo-NHS; Sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate. Grades: > 98.0 %. CAS No. 106627-54-7. Molecular formula: C4H4NNaO6S. Mole weight: 217.13. | |
| NI 57 | NI 57 is a BRPF bromodomain inhibitor. It is selective for BRPFs over other bromodomains. Synonyms: NI-57; NI 57; NI57. 4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide. Grades: ≥98% by HPLC. CAS No. 1883548-89-7. Molecular formula: C19H17N3O4S. Mole weight: 383.42. | |
| NIBR0213 | NIBR0213 is an orally bioavailable and selective antagonist of sphingosine-1-phosphate receptor-1 (S1P1). NIBR0213 is identified as a promising agent for autoimmune disease therapy. Uses: Sphingosine 1 phosphate receptor modulators. Synonyms: NIBR-0213; NIBR 0213; GTPL6997; (2S)-2-[[4-[3-[[(1R)-1-(4-chloro-3-methylphenyl)ethyl]amino]phenyl]-2,6-dimethylbenzoyl]amino]propanoic acid. Grades: ≥98%. CAS No. 1233332-14-3. Molecular formula: C27H29ClN2O3. Mole weight: 465. | |
| NIBR189 | (2E)-3-(4-Bromophenyl)-1-[4-(4-methoxybenzoyl)-1-piperazinyl]-2-propen-1-one recently known as NIBR 189, is a selective Epstein-barr virus-induced gene 2 (EBI-2) receptor antagonist, resulting in a modulation of immune responses related to auto-immune diseases. Synonyms: NIBR-189; NIBR189. Grades: >98%. CAS No. 1599432-08-2. Molecular formula: C21H21BrN2O3. Mole weight: 429.31. | |
| Niclofolan | Niclofolan is a biphenyl anthelmintic compound. It is used orally towards the treatment of Fasciola hepatica infection. It is used for the control of cattle and sheep trematode disease. Uses: Niclofolan is used orally towards the treatment of fasciola hepatica infection. it is used for the control of cattle and sheep trematode disease. Synonyms: NICLOFOLAN; Niclofoian; 1'-biphenyl)-2,2'-diol, 5,5'-dichloro-3,3'-dinitro-(; 3,3'-dichloro-5,5'-dinitro-o,o'-biphenol; 4,4'-dichloro-6,6'-dinitro-o,o'-biphenol; 5,5'-dichloro-2,2'-dihydroxy-3,3'-dinitrobiphenyl; 5,5'-dichloro-3,3'-dinitro(1,1'-biphenyl)-2,2'-. Grades: >98 %. CAS No. 10331-57-4. Molecular formula: C12H6Cl2N2O6. Mole weight: 345.09. | |
| Niclosamide piperazine salt | Synonyms: Niclosamide Piperazine; 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide piperazine. CAS No. 34892-17-6. Molecular formula: C17H18Cl2N4O4. Mole weight: 413.255. | |
| Nicodicosapent | Nicodicosapent is a bio-active molecular as an antihypertrigylceridemic drug candidate. Uses: Antihypertrigylceridemic drug candidate. Synonyms: N-(2-((5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenamido)ethyl)nicotinamide. Grades: 98%. CAS No. 1269181-69-2. Molecular formula: C28H39N3O2. Mole weight: 449.64. | |
| Nicotinic acid N-oxide | Nicotinic acid N-oxide is used to treat hyperlipoidemia. Synonyms: 1-oxidopyridin-1-ium-3-carboxylic acid. Grades: 99 %. CAS No. 2398-81-4. Molecular formula: C6H5NO3. Mole weight: 139.11. | |
| Nifuratel Impurity 2 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Synonyms: Nifuratel Impurity 2 (Mixture of Diastereomers). Grades: 95%. CAS No. 1445990-09-9. Molecular formula: C10H11N3O6S. Mole weight: 301.28. | |
| Nifuratel Impurity 5 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Synonyms: Nifuratel impurity 003. Grades: 95%. Molecular formula: C10H11N3O6S. Mole weight: 301.28. | |
| Nifuratel Impurity 6 | One impurity of Nifuratel. Nifuratel is a broad antibacterial spectrum agent, which is used as an antibacterial, antifungal, and antiprotozoal. Synonyms: 3-Amino-5-((methylthio)methyl)oxazolidin-2-one; 3-amino-5-(methylsulfanylmethyl)-1,3-oxazolidin-2-one; 2-Oxazolidinone,3-amino-5-[(methylthio)methyl]-; EINECS 247-064-8; DTXSID40948417; CS-0165799; 3-Amino-5-methylmercaptomethyl-2-oxazolidinone; 3-AMINO-5-[(METHYLSULFANYL)METHYL]-1,3-OXAZOLIDIN-2-ONE; 3-amino-5-((methylthio)methyl)oxazolidin-2-one? (Nifuratel Impurity pound(c). Grades: 95%. CAS No. 25517-72-0. Molecular formula: C5H10N2O2S. Mole weight: 162.21. | |
| Nigakihemiacetal B | Nigakihemiacetal B is found in the barks of Ailanthus altissima (Mill.) Swingle. Synonyms: Neoquassine; Neoquassin; Simalikahemiacetal A. Grades: > 95%. CAS No. 76-77-7. Molecular formula: C22H30O6. Mole weight: 390.47. | |
| NIH-12848 | NIH-12848 is putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor (IC50 = 1 μM) but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. Synonyms: N-(thiophen-2-ylmethyl)-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine; NCGC00012848-02; NIH-12848; NIH 12848; NIH12848, NCGC00012848-02. CAS No. 959551-10-1. Molecular formula: C20H14F3N3S. Mole weight: 385.41. | |
| Nilotinib | Nilotinib is a Bcr-Abl inhibitor with IC50 less than 30 nM. It is under investigation as a possible treatment for chronic myelogenous leukemia (CML). Synonyms: Tasigna; AMN107; AMN 107; AMN-107; BW 33A, 51W89. Grades: ≥98%. CAS No. 641571-10-0. Molecular formula: C28H22F3N7O. Mole weight: 529.52. | |
| Niludipine | Niludipine, a safe antianginal Ca2+-antagonist, is a drug with broad effectiveness for various types of angina pectoris. Uses: Calcium channel blockers. Synonyms: BAY-a 7168; Bay a 7168; NILUDIPINE;(2-propoxyethyl)ester; 5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-bis; bay-a7168; bis(2-propoxyethyl)1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedi;niludipin; Bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl). Grades: >98%. CAS No. 22609-73-0. Molecular formula: C25H34N2O8. Mole weight: 490.55. | |
| NIM811 | NIM811 is a dual inhibitor of mitochondrial permeability transition and cyclophilin. It exhibits potent in vitro inhibitory activity against hepatitis C virus (HCV). Synonyms: (Melle-4)cyclosporin; Sdz-nim-811; NIM-811; NIM 811. Grades: 98.82%. CAS No. 143205-42-9. Molecular formula: C62H111N11O12. Mole weight: 1202.61. | |
| Nimesulide Impurity E | An impurity of Nimesulide, which is a selective COX-7 inhibitor. Synonyms: N-(Methylsulfonyl)-4-(desnitro) Nimesulide; N-(Methylsulfonyl)-N-(2-phenoxyphenyl)methanesulfonamide. Grades: > 95%. CAS No. 905858-63-1. Molecular formula: C14H15NO5S2. Mole weight: 341.41. | |
| Nimesulide Impurity F | An impurity of Nimesulide, which is a selective COX-5 inhibitor. Synonyms: N-Methylsulfonyl Nimesulide; N-(Methylsulfonyl)-N-(4-nitro-2-phenoxyphenyl)methanesulfonamide; N-(Methylsulfonyl)-4'-nitro-2'-phenoxymethanesulfonanilide. Grades: > 95%. CAS No. 51765-72-1. Molecular formula: C14H14N2O7S2. Mole weight: 386.4. | |
| Nintedanib (Intedanib) | Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Synonyms: Vargatef; BIBF-1120; BIBF 1120; BIBF1120; Intedanib. Grades: ≥98%. CAS No. 656247-17-5. Molecular formula: C31H33N5O4. Mole weight: 539.62. | |
| Niraparib | Niraparib is an inhibitor of PARP, which was approved by FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy. Synonyms: MK-4827; MK 4827; MK4827; (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; ZEJULA; 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide. CAS No. 1038915-60-4. Molecular formula: C19H20N4O. Mole weight: 320.396. | |
| NITD 008 | NITD008 is a flavivirus inhibitor. It was developed as a potential treatment for flavivirus infections, and shows broad spectrum antiviral activity. Synonyms: NITD008; NITD 008; NITD-008; 7-(2-C-Ethynyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Grades: ≥98% by HPLC. CAS No. 1044589-82-3. Molecular formula: C13H14N4O4. Mole weight: 290.27. | |
| Nizaracianine | Nizaracianine is a diagnostic imaging agent. Synonyms: Nizaracianina; Nizaracianinum; 3-[4-({(6E)-6-[(2E)-2-{3,3-dimethyl-5-sulfonato-1-[3-(trimethylazaniumyl)propyl]-1,3-dihydro-2H-indol-2-ylidene}ethylidene]-2-[(1E)-2-{3,3-dimethyl-5-sulfonato-1-[3-(trimethylazaniumyl)propyl]-3H-indol-1-ium-2-yl}ethen-1-yl]cyclohex-1-en-1-yl}oxy)phenyl] propanoate. CAS No. 1239619-02-3. Molecular formula: C51H66N4O9S2. Mole weight: 943.2. | |
| NK-1145 Hydrochloride | The hydrochloride salt form of NK-1145, an azabicyclo derivative, has been found to be a parasympatholytic drug that could induce stimulation and excitement. Synonyms: NK-1145 hydrocholdoride; NK1145; NK 1145; NK-1145; Phenyl tropan-3alpha-yl ester; NK 1145; Tropine-3-beta-phenyl ether hydrochloride; 8-methyl-3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride(1:1). Grades: 98%. CAS No. 16487-37-9. Molecular formula: C14H20ClNO. Mole weight: 253.77. | |
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