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Kuwanon E
Kuwanon E is a flavonoid compound found in the root bark of Morus alba L. Synonyms: (S)-2-[5-[(E)-3,7-Dimethyl-2,6-octadienyl]-2,4-dihydroxyphenyl]-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; 5'-[(E)-3,7-Dimethyl-2,6-octadienyl]-2',4',5,7-tetrahydroxyflavanone. Grade: >98%. CAS No. 68401-05-8. Molecular formula: C25H28O6. Mole weight: 424.5.
(Kyn25)-Liraglutide trifluoroacetate salt
(Kyn25)-Liraglutide trifluoroacetate salt is an impurity of Liraglutide. Synonyms: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Kyn-Leu-Val-Arg-Gly-Arg-Gly-OH trifluoroacetate salt. Molecular formula: C171H265N43O52.C2HF3O2. Mole weight: 3869.20.
Labd-13(E)-ene-8α,15-diol
Labd-13-ene-8,15-diol is a natural diterpenoid found in the fruits of Zizyphus jujuba. Synonyms: (1R,2R,4aS,8aS)-1-((E)-5-hydroxy-3-Methylpent-3-en-1-yl)-2,5,5,8a-tetraMethyldecahydronaphthalen-2-ol. Grade: >98%. CAS No. 10267-31-9. Molecular formula: C20H36O2. Mole weight: 308.5.
Latinone
Latinone, a member of the macrolide antibiotic class, is a highly effective drug that promptly halts the propagation and procreates curtailment in various types of bacterial infections occurring in the urinary tract, skin, and pneumonia. This striking agent is contraindicated in viral disorders and should only be administered for bacterial infections. Synonyms: latinone; 79157-36-1; starbld0000931; CHEMBL453557; HY-N7326. Grade: 98.0%. CAS No. 79157-36-1. Molecular formula: C22H16O5. Mole weight: 360.366.
Laurifoline
Laurifoline isolated from the herbs of Lindera aggregata. Uses: Anti-hbv activities. Synonyms: (6aS)-5,6,6a,7-Tetrahydro-1,9-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolin-6-ium. Grade: 96%. CAS No. 7224-61-5. Molecular formula: C20H24NO4. Mole weight: 342.4.
Lehmbachol D
Lehmbachol D is a natural compound, aidng in the research of skin infections and inflammatory maladies. Grade: 97.5%. CAS No. 913556-40-8. Molecular formula: C26H26O8. Mole weight: 466.488.
[Leu27]-Melan-A, MART 1 (26-35)
[Leu27]-Melan-A, MART 1 (26-35) is an analog of MART-1 (26-35), which is an immunodominant antigen from melanocyte/melanoma (Melan-A/MART) protein. [Leu27]-Melan-A MART 1 (26-35) shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural MART 1 (26-35). Synonyms: H-Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH; Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val; Melan-A/MART-1 analog. CAS No. 204060-45-7. Molecular formula: C45H80N10O14. Mole weight: 985.18.
Leuconolam
Leuconolam comes from the herbs of Alstonia scholaris. Synonyms: (8aR,12aS,14bS)-8a-Ethyl-7,8,8a,10,11,12a-hexahydro-12a-hydroxyindolizino[8,1-ef][1]benzazonine-6,13(5H,9H)-dione. Grade: 0.97. CAS No. 93710-27-1. Molecular formula: C19H22N2O3. Mole weight: 326.4.
Leucosceptoside A
Leucosceptoside A is a natural compound isolated from the dried roots of Clerodendrum bungei. Grade: 97.0%. CAS No. 83529-62-8. Molecular formula: C30H38O15. Mole weight: 638.619.
Leucoside
Leucoside is a flavonoid isolated from the herbs of Aesculus L. Synonyms: Kaempferol 3-sambubioside; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 2-O-β-D-x ylopyranosyl-β-D-glucopyranoside. Grade: > 95%. CAS No. 27661-51-4. Molecular formula: C26H28O15. Mole weight: 580.5.
Liangshanin A
Liangshanin A is a natural diterpenoid found in the herbs of Rabdosia bulleyana. Synonyms: Kaura-1,16-diene-3,15-dione, 7,14-dihydroxy-, (7a,14R)-. Grade: >98%. CAS No. 122717-54-8. Molecular formula: C20H26O4. Mole weight: 330.4.
Licochalcone A
Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It is a potent membrane-active agent that transforms normal erythrocytes into echinocytes. It exhibits potent antimalarial activity and might be developed into a new antimalarial drug. It had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy. Synonyms: 4,4'-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone; 7-Dimethoxycoumarin; 3-Dimethylallyl-4,4'-dihydroxy-6-methoxychalcone; (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; (2E)-3-[5-(1,1-Dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-; 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (E)-. Grade: >98%. CAS No. 58749-22-7. Molecular formula: C21H22O4. Mole weight: 338.40.
Licochalcone B
Licochalcone B is extracted from the roots of Glycyrrhiza glabra L. It inhibits the adhesion,invasion and metastasis of human malignant bladder cancer T24 cells. It could significantly reduce the LPS-induced production of NO, TNFalpha and MCP-1. Synonyms: (2E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 3-(3,4-dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (E)-; (E)-3-(3,4-Dihydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; 3,4,4'-Trihydroxy-2-methoxy-trans-chalcone; 3,4,4'-Trihydroxy-2-Methoxychalcone. Grade: >98%. CAS No. 58749-23-8. Molecular formula: C16H14O5. Mole weight: 286.28.
Ligustroflavone
Ligustroflavone is isolated from Ligustrum vulgare, which shows anti-inflammatory and antioxidant activity. It has the potential as a calcium-sensing receptor (CaSR) antagonist. Uses: Anti-inflammatory. Synonyms: ligustroflavone; 7-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1->2)-O-[6-deoxy-alpha-L-mannopyranosyl-(1->6)]-beta-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)- 4H-1-benzopyran-4-one; Nuezhenoside; Ligustroflavone(Nuezhenoside). Grade: >98%. CAS No. 260413-62-5. Molecular formula: C33H40O18. Mole weight: 724.67.
Ligustroside
Ligustroside is isolated from the seeds of Ligustrum lucidum. Uses: Anti-inflammatory. Synonyms: (2S)-3-[(E)-Ethylidene]-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4α-acetic acid 2-(4-hydroxyphenyl)ethyl ester. Grade: 98%. CAS No. 35897-92-8. Molecular formula: C25H32O12. Mole weight: 524.51.
Limonin
Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability. Uses: Anticancer; antioxidant; anti-inflammatory. Synonyms: Citro; Dictamnolactone; Limonin; Evodin; Limonine; NSC 36508; Obaculactone. Grade: >98%. CAS No. 1180-71-8. Molecular formula: C26H30O8. Mole weight: 470.51.
Linarin
Linarin is a flavone glycoside isolated from the herb of Uncaria sinensis (Oliv.) Havil. It is also an impurity of Diosmin, a medication used for the treatment of various disorders of blood vessels. Synonyms: Acacetin-7-O-b-D-rutinoside; Buddleflavonoloside; Linarigenin glycoside. Grade: 98%. CAS No. 480-36-4. Molecular formula: C28H33O14. Mole weight: 593.55.
Linaroside
Linaroside is a flavonoid glycoside isolated from some species of Linaria. Grade: 98.5%. CAS No. 53452-12-3. Molecular formula: C23H24O11. Mole weight: 476.44.
Linderaspirone A
Linderaspirone A, that is extracted from the roots of Lindera aggregata( Sims) Kosterm, showed significant activity against glucosamine-induced insulin resistance. Synonyms: (8R,16R)-rel-2,3,6,11,12,14-Hexamethoxy-8,16-diphenyldispiro[4.3.4.3]hexadeca-2,6,11,14-tetraene-1,4,10,13-tetrone. Grade: >98%. CAS No. 1235126-46-1. Molecular formula: C34H32O10. Mole weight: 600.6.
Liquiritigenin
Liquiritigenin is a natural flavonoid compound found in the root of Glycyrrhiza uralensis Fisch. Liquiritigenin exhibits anti-inflammatory, antihyperlipidemic and antiallergic activities. Liquiritigenin is an estrogenic compound which acts as an agonist s. Synonyms: 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (2S)-; (2S)-2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-, (S)-; Flavanone, 4',7-dihydroxy-; (-)-(2S)-7,4'-Dihydroxyflavanone; (-)-(S)-4',7-Dihydroxyflavanone; (-)-Liquiritigenin; (2S)-Liquiritigenin; 4',7-Dihydroxyflavanone; 7,4'-Dihydroxyflavanone; Menerba. Grade: >98%. CAS No. 578-86-9. Molecular formula: C15H12O4. Mole weight: 256.25.
Liquiritin
Liquiritin is a natural flavonoid compound found in the root of Glycyrrhiza glabra L. Liquiritin shows potential antidepressant-like effection and can increase SOD activity, inhibit lipid peroxidation, and lessen production of MDA. Uses: Antidepressant. Synonyms: 4,7-Dihydroxyflavanone-4-(b-D-glucopyranoside); Likviritin; Liquiritoside. Grade: >98%. CAS No. 551-15-5. Molecular formula: C21H22O9. Mole weight: 418.39.
Litseglutine B, also called 2-Hydroxy-1,10,11-trimethoxyaporphine, is a natural alkaloid found in the herbs of Litsea glutinosa. Synonyms: 2-Hydroxy-1,10,11-trimethoxyaporphine. Grade: >95%. CAS No. 25368-01-8. Molecular formula: C20H23NO4. Mole weight: 341.4.
L-Lactide
Synthesis of biodegradable homo- and copolymers. Synonyms: L-(-)-Lactide; Lactide, L-; L,L-Dilactide; (3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione. Grade: 98%. CAS No. 4511-42-6. Molecular formula: C6H8O4. Mole weight: 144.13.
LOCHNERINE
Lochnerine is a natural alkaloid found in the herbs of Catharanthus roseus (L.) G. Don. Synonyms: 10-Methoxysarpagan-17-ol; 10-Methoxynormacusine B; 10-O-Methylsarpagine. Grade: >98%. CAS No. 522-47-4. Molecular formula: C20H24N2O2. Mole weight: 324.4.
Loganic acid
Loganic acid and geniposide exhibit both sides effect on superoxide generation. Uses: Clearing heat. Synonyms: (1S,4aS,6S,7R,7aS)-1-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylic acid; Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, [1S-(1α,4aα,6α,7α,7aα)]-; Cyclopenta[c]pyran-4-carboxylic acid, 1α-(β-D-glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-6α-hydroxy-7α-methyl-; Loganin acid. Grade: 98%. CAS No. 22255-40-9. Molecular formula: C16H24O10. Mole weight: 376.36.
Loliolide
Loliolide is a germination inhibitor that is isolated from Sargassum ringgoldianum subsp. coreanum. Loliolide exhibits antioxidant activity to protect the cells against H2O2-induced cell damage or apoptosis. Synonyms: (3S,5R)-Loliolide. Grade: 98.0%. CAS No. 5989-2-6. Molecular formula: C11H16O3. Mole weight: 196.246.
Longikaurin E
Longikaurin E is isolated from the herbs of Rabdosia nervosa. It could be a promising anti-pancreatic agent. Uses: Antibacterial. Synonyms: 11α-Acetoxy-7α,20-epoxy-6β,7-dihydroxykaur-16-en-15-one; (4aR,5S,6R,6aS,9S,11R,11aS,11bS)-5,6-dihydroxy-4,4-dimethyl-8-methylene-7-oxododecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-11-yl acetate. Grade: 98%. CAS No. 77949-42-9. Molecular formula: C22H30O6. Mole weight: 390.5.
Longistylumphylline A
Longistylumphylline A is isolated from the herbs of Daphniphyllum macropodum. Synonyms: Longistylumphylline A; 1H-11,12c-Methanocyclopent[1,8]azuleno[4,5-a]indolizine-2-carboxylic acid, 3,4,5,6,6a,7,9,10,11,12,12a,12b-dodecahydro-10,12b-dimethyl-13-oxo-, methyl ester, (6aR,10R,11S,12aS,12bR,12cS)-rel-(-)-. Grade: 96.5%. CAS No. 857672-34-5. Molecular formula: C23H29NO3. Mole weight: 367.5.
Lophanthoidin E
Lophanthoidin E, also called (6β,7α)-6,7,12-Trihydroxy-11,14-dioxoabieta-8,12-dien-16-yl aceta te, is a natural diterpenoid found in the herbs of Rabdosia lophanthoides. Synonyms: (6β,7α)-6,7,12-Trihydroxy-11,14-dioxoabieta-8,12-dien-16-yl aceta te. Grade: >95%. CAS No. 120462-45-5. Molecular formula: C22H30O7. Mole weight: 406.5.
Lophanthoidin F
Lophanthoidin F is a natural diterpenoid found in the herbs of Rabdosia lophanthoides. Synonyms: (6β,7α)-7-Ethoxy-6,12-dihydroxy-11,14-dioxoabieta-8,12-dien-16-yl acetate. Grade: >95%. CAS No. 120462-46-6. Molecular formula: C24H34O7. Mole weight: 434.5.
Loureirin A
Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-related peptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway. Synonyms: 3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone. Grade: 98.5%. CAS No. 119425-89-7. Molecular formula: C17H18O4. Mole weight: 286.32.
Loureirin B
Loureirin B, isolated from the herbs of Dracaena cochinchinensis, is a channel blocker of Kv1.3 by interacting with amino acid residues in its selective filter region. Direct inhibition of Kv1.3 in T cells by SD and Loureirin B might be the cellular and molecular basis of SD-mediated immunosuppression. Loureirin B could evoke the elevation of [Ca(2+)](I) in a dose-dependent manner. Loureirin B is also the effective component in dragon's blood modulating sodium currents in trigeminal ganglion neurons. Uses: Analgesic/anti-inflammatory. Synonyms: 1-Propanone,1-(4-hydroxyphenyl)-3-(2,4,6-triMethoxyphenyl). Grade: >98%. CAS No. 119425-90-0. Molecular formula: C18H20O5. Mole weight: 316.35.
Lucidenic acid D, a triterpenoid compound, is extracted from Ganoderma lucidum and is reported to be endowed with multifarious biological activities, such as anti-cancer, anti-inflammatory, and antioxidant properties. With its remarkable potential to stimulate apoptosis in cancer cells, lucidenic acid D stands out as an effective therapeutic candidate for combating cancer and other ailments. Synonyms: Lucidenic acid D; Lucidenic acid D; 298665-16-8; LucidenicacidD; UNII-4C2000605T. Grade: >98%. CAS No. 98665-16-8. Molecular formula: C29H38O8. Mole weight: 514.61.
Lup-20(29)-ene-3α,23-diol
Lup-20(29)-ene-3α,23-diol isolated from the barks of Glochidion macrophyllum. Uses: Anti-hiv activity. Synonyms: (1R,3aR,5aR,5bR,7aR,8R,9R,11aR,11bR,13aR,13bR)-8-(hydroxymethyl)-3a,5a,5b,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol. Grade: 0.985. CAS No. 32451-85-7. Molecular formula: C30H50O2. Mole weight: 442.7.
Lupenone
Lupenone is isolated from the roots of Pueraria thomsonii Benth. It effectively inhibited adipocyte differentiation through downregulating the related transcription factor, particularly the PPARγ gene. Synonyms: 18-Lupen-3-one; 5α-Lup-20(29)-en-3-one. Grade: 98%. CAS No. 1617-70-5. Molecular formula: C30H48O. Mole weight: 424.7.
Lupeol
Lupeol is isolated from the flower of Chrysanthemum morifolium. It enhances the radiosensitivity of SMMC-7721 cells in vitro and in vivo. Uses: Anti-inflammatory agents. Synonyms: Fagarasterol; Clerodol; Monogynol B. Grade: 98%. CAS No. 545-47-1. Molecular formula: C30H50O. Mole weight: 426.7.
Luteolin
Luteolin is an anti-inflammatory, antioxidant and free radical scavenger. Luteolin inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. It also inhibits TNF-α-induced COX-2 expression, and phosphodiesterase with with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM for PDE1-5 respectively. It inhibits proliferation of Lewis lung carcinoma cells in vivo. Luteolin is a natural compound found in the leaves of Dracocephalum ruyschiana L. It can be used in cosmetics material. Uses: Adcs cytotoxin. Synonyms: 3',4',5,7-Tetrahydroxyflavone; Digitoflavone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; Flacitran. Grade: ≥98%. CAS No. 491-70-3. Molecular formula: C15H10O6. Mole weight: 286.24.
Luteolin 5-methyl ether
Luteolin 5-methyl ether, a flavone compound of natural origin with potent pharmacological effects, can be obtained from a variety of plant species. Its therapeutic potential encompasses a broad spectrum of health conditions such as cancer, cardiovascular diseases, diabetes, and neurodegenerative disorders, primarily due to its antioxidant, anti-inflammatory, and antitumor properties. The inspiring results from studies conducted in this realm suggest that Luteolin 5-methyl ether is a promising candidate for the development of novel therapeutic agents. Synonyms: 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-. Grade: 98.0%. CAS No. 58115-29-0. Molecular formula: C16H12O6. Mole weight: 300.27.
Luteolin 7-O-glucoside
Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin. Synonyms: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl-D-glucopyranoside; Cynaroside; Luteoloside; Luteolin 7-glucoside. Grade: 98% (HPLC). CAS No. 5373-11-5. Molecular formula: C21H20O11. Mole weight: 448.39.
Luteone
Luteone is a natural flavonoid isolated from the herbs of Erythrina variegata Linn. Synonyms: 3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one. Grade: >98%. CAS No. 41743-56-0. Molecular formula: C20H18O6. Mole weight: 354.4.
Luvangetin
Luvangetin is a coumarin isolated from the stem bark of Zanthoxylum ailanthoides. Luvangetin exhibits inhibition against superoxide anion (O2 -) generation and elastase release by human neutrophils in response to fMLP/CB. Synonyms: 10-methoxy-2,2-dimethylpyrano[3,2-g]chromen-8-one. Grade: 99.0%. CAS No. 483-92-1. Molecular formula: C15H14O4. Mole weight: 258.273.
Lycojaponicuminol C
Lycojaponicuminol C, an organic compound extracted from natural sources, possesses intriguing antitumor effects. Preclinical investigations have demonstrated its modulating capacity over the carcinogenic progression of various types of tumors, including breast and colon. The molecular mechanisms behind its cytotoxicity involve impeding malignant proliferation and provoking programmed cell death in cancer cells. Synonyms: Lycojaponicuminol C; AKOS040763061; 1651839-34-7. Grade: 97.5%. CAS No. 1651839-34-7. Molecular formula: C29H48O4. Mole weight: 460.698.
Lycorine hydrochloride
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be highly poisonous, or even lethal, when ingested in certain quantities. Symptoms of lycorine toxicity are vomiting, diarrhea, and convulsions. Uses: Adcs cytotoxin. Synonyms: Lycorine hydrochloride; 2188-68-3; Lycorine chloride; Lycorine HCl; Licorin hydrochloride; Lycorine (hydrochloride); 58F70VH0HS; 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-; (1S,2S,3a1S,12bS)-2,3a1,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol hydrochloride; (1S,17S,18S,19S)-. Grade: 98 %. (NMR). CAS No. 2188-68-3. Molecular formula: C13H19NO4S. Mole weight: 299.45.
Lyoniresinol
Lyoniresinol, a natural lignan isolated from the root of Vitex negundo,is one of the eight lignans purified from methanol which has robust tyrosinase inhibitory capacity. Lyoniresinol exhibits the activity of antioxidative, and it decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activating ERK signaling, which downregulates MITF, tyrosinase, but not TRP-1 and TRP-2 protein expression, it can perhaps be incorporated into clinical dermatologic use as a skin lightening agent. Uses: Anti-melanogenic; anti-oxidant. Synonyms: (1S)-1α-(3,5-Dimethoxy-4-hydroxyphenyl)-6,8-dimethoxy-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2β,3α-dimethanol. Grade: >98%. CAS No. 14464-90-5. Molecular formula: C22H28O8. Mole weight: 420.5.
(Lys22)-Amyloid β-Protein (1-42)
(Lys22)-Amyloid β-Protein (1-42), the Italian mutation (E22K), aggregates faster than the wild-type sequence. Synonyms: Amyloid β-Protein (1-42) Italian Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-lysyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine. Grade: ≥95%. CAS No. 383200-59-7. Molecular formula: C204H316N56O58S. Mole weight: 4513.16.
(Lys7)-Phalloidin
(Lys7)-Phalloidin. Synonyms: Bicyclic(Ala-DThr-Cys-cis-4-hydroxy-Pro-Ala-2-mercapto-Trp-Lys)(S-3→6); Cyclo(-Ala-D-Thr-Cys-cis-Hyp-Ala-Trp-Lys) (Sulfide bond between Cys and indol-2-yl); (1S,14R,18S,20S,23S,28S,31S,34R)-28-(4-Aminobutyl)-18-hydroxy-34-[(1S)-1-hydroxyethyl]-23,31-dimethyl-12-thia-10,16,22,25,27,30,33,36-octaazapentacyclo[12.11.11.03,11.04,9.016,20]hexatriaconta-3(11),4,6,8-tetraene-15,21,24,26,29,32,35-heptone. Grade: ≥95%. CAS No. 1393889-01-4. Molecular formula: C35H49N9O9S. Mole weight: 771.88.
LysoTracker Red DND-99
Lysotracker probe is an acidic fluorescent probe, used for labeling and tracing acidic organelles in living cells. These probes have several important features, including highly selective targeting of acidic organelles and nanomolar concentration to effectively label living cells. In addition, the LysoTracker series has several fluorescent colors, which are particularly suitable for multi-color labeling experiments. The Lysotracker probe contains a fluorescein attached to a weak base, which is partially protonated at neutral pH, can freely penetrate the cell membrane and is typically concentrated on spherical organelles. The study found that the Lysotracker probe must be at a very low concentration (usually about 50nM) in order to obtain excellent selectivity. Although the retention mechanism of these probes has not been fully studied, it is likely to be related to the protonation and retention of acidic organelles. Even if the cells are treated with weak alkaline cell permeation compounds, the staining results are usually not reversible. The endocytosis kinetics study of the Lysotracker probe shows that the uptake rate of the dye into living cells is only a few seconds. However, these lysosomal probes can cause lysosomes to be alkalized, for example, long-term incubation can induce an increase in lysosomal pH. Therefore, it is recommended to incubate the cells with the probe for only 1-5min before imaging. LysoTra
Machigline
Machigline is a phenolic oxoaporphine alkaloid isolated from Machilus macrantha. Grade: 97.0%. CAS No. 87264-30-0. Molecular formula: C18H11NO5. Mole weight: 321.289.
Macrocarpal A
Macrocarpal A is a cytotoxic alkaloid isolated from the branch of Eucalyptus globulus. Uses: Antifouling activity; antibacterial activity. Synonyms: 2,4,6-Trihydroxy-5-[(1R)-1-[(1aβ,4R,4aβ,7aα,7bβ)-1,1,4,7-tetramethyl-4β-hydroxydecahydro-1H-cyclopropa[e]azulene-7α-yl]-3-methylbutyl]isophthalaldehyde. Grade: 97.5%. CAS No. 132951-90-7. Molecular formula: C28H40O6. Mole weight: 472.6.
Macrocarpal B
Macrocarpal B, which can be found in the branch of Eucalyptus globulus, shows antifouling activity. Uses: Antibacterial/antifouling. Synonyms: 5-[(1S)-1-[(1aR,4R,4aR,7S,7aS,7bR)-4-hydroxy-1,1,4,7-tetramethyl-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxybenzene-1,3-dicarbaldehyde; 1,3-Benzenedicarboxaldehyde, 5-[(1S)-1-[(1aR,4R,4aR,7S,7aS,7bR)-decahydro-4-hydroxy-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen-7-yl]-3-methylbutyl]-2,4,6-trihydroxy-. Grade: >98%. CAS No. 142698-60-0. Molecular formula: C28H40O6. Mole weight: 472.6.
Macrocarpal J
Macrocarpal J is isolated from the branch of Eucalyptus globulus. Uses: Anti-bacterial activity. Synonyms: 2,4,6-trihydroxy-5-[(1S)-1-[(4S)-4-hydroxy-6-(2-hydroxypropan-2-yl)-4,8a-dimethyl-1,2,3,4a,5,6,7,8-octahydronaphthalen-1-yl]-3-methylbutyl]benzene-1,3-dicarbaldehyde. Grade: > 95%. CAS No. 179603-47-5. Molecular formula: C28H42O7. Mole weight: 490.6.
Macrocarpal L
Macrocarpal L is isolated from the branch of Eucalyptus globulus. Synonyms: 2,4,6-Trihydroxy-5-{(1R)-1-[(1aS,3aS,4S,7R,7aR,7bS)-7-hydroxy-1,1 ,3a,7-tetramethyldecahydro-1H-cyclopropa[a]naphthalen-4-yl]-3-met hylbutyl}isophthalaldehyde. Grade: 98%. CAS No. 327601-97-8. Molecular formula: C28H40O6. Mole weight: 472.6.
Macrocarpal N
Macrocarpal N is isolated from the twigs of Eucalyptus globules Labill. Synonyms: 5-[(1S)-1-{(1R,2R)-2-[(1R,3R)-2,2-Dimethyl-3-(3-oxobutyl)cyclopro pyl]-1-methyl-3-oxocyclopentyl}-3-methylbutyl]-2,4,6-trihydroxyis ophthalaldehyde. Grade: 97.5%. CAS No. 221899-21-4. Molecular formula: C28H38O7. Mole weight: 486.6.
Madecassic acid
Madecassic acid is a natural triterpenoid found in the herbs of Centella asiatica (L.) Urban. Madecassic acid has strong metabolic capacity. Madecassic acid is used as a wound-healing, anti-inflammatory and anti-cancer agent. Synonyms: (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid; Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,4α,6β)-; Urs-12-en-28-oic acid, 2α,3β,6β,23-tetrahydroxy-; Brahmic acid; (2α,3β,4α,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid; 2α,3β,6β,23-Tetrahydroxy-urs-12-en-28-oic acid; 6β-Hydroxyasiatic acid; NSC 88135. Grade: >98%. CAS No. 18449-41-7. Molecular formula: C30H48O6. Mole weight: 504.70.
Madecassoside
Madecassoside is a neuroprotective and may be useful in reducing the damage caused by stroke. Madecassoside also has whitening effect, thus can be used in cosmetic material. Uses: Anti-arthritis. Synonyms: 6-Deoxy-a-L-mannopyranosyl-1-4-b-D-glucopyranosyl-1-6-b-D-glucopyranosyl-(2a,3b,4a,6b)-2,3,6,23-tetrahydroxyurs-12-en-28-oate. Grade: >98%. CAS No. 34540-22-2. Molecular formula: C48H78O20. Mole weight: 975.12.
Magnolianin
Magnolianin is isolated from the bark of Magnolia obovata. Synonyms: 1,2-Benzenediol, 5-[(2R,3R)-2,3-dihydro-3-[[(2'-hydroxy-5,5'-di-2-propen-1-yl[1,1'-biphenyl]-2-yl)oxy]methyl]-7-(2-propen-1-yl)-5-[4-(2-propen-1-yl)phenoxy]-1,4-benzodioxin-2-yl]-3-[4-(2-propen-1-yl)phenoxy]-, rel-. Grade: > 95%. CAS No. 147663-91-0. Molecular formula: C54H50O8. Mole weight: 827.00.
Magnolol
Magnolol is a bioactive lignin found in Magnolia officinalis and acts as a TNF-α and nitric oxide (NO) inhibitor. It exhibits potential therapeutic effect on anxiety, cough, headache and allergies. Magnolol has antifungal, antibacterial, anti-oxidative, antidepressant-like, anti-tumor, and neuroprotective effects. It can be used in cosmetics material. It is a plant polyphenol that can inhibit tyrosinase, block melanin synthesis, reduce skin pigment intensity, absorb UV, prevent photoaging, reduce sun damage and age spot formation, and whiten and lighten spots. It also has the anti-glycation effect, can effectively improve skin tone and skin texture, prevent the generation of age spots, remove red bloodlines, and improve skin blood microcirculation. It has the activity of antibacterial, anti-inflammatory, antioxidant, oil control, acne, promoting healing, and can be widely used in anti-acne, deodorization, acne and other products. Uses: Anti-oxidative; antimicrobial; antifungal. Synonyms: 5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol; 5,5'-Diallyl-2,2'-biphenyldiol; 5,5'-Diallyl-2,2'-dihydroxybiphenyl; 2,2'-Bichavicol; 2,2'-Bichavicol; 5,5'-Di-2-propen-1-yl[1,1'-biphenyl]-2,2'-diol; E 100338; NSC 293099. Grade: >95%. CAS No. 528-43-8. Molecular formula: C18H18O2. Mole weight: 266.34.
Magnoloside A
Magnoloside A isolated from the bark of Magnolia obovata. It is used for neurosis and gastrointestinal complaints as a japanese traditional medicine. Uses: Antistress. Synonyms: 2-(3,4-Dihydroxyphenyl)ethyl 2-O-(6-deoxy-α-L-mannopyranosyl)-3-O -[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-allopyranoside. Grade: 0.96. CAS No. 113557-95-2. Molecular formula: C29H36O15. Mole weight: 624.6.
Mahanine
Mahanine, a carbazole alkaloid (occurs in the edible part of Micromelum minutum, Murraya koenigii and related species), is a DNA minor groove binding agent with potent anticancer activity. Mahanine exhibits antileishmanial activity and can be used for Leishmania infection treatment research. Synonyms: (-)-Mahanine; (R)-3,5-Dimethyl-3-(4-methylpent-3-en-1-yl)-3,11-dihydropyrano[3,2-a]carbazol-9-ol. Grade: 95%. CAS No. 28360-49-8. Molecular formula: C23H25NO2. Mole weight: 347.46.
Mal-PEG2-NHS ester
Mal-PEG2-NHS ester is a non-cleavable ADC linker containing the Maleimide group, 2-unit PEG, and NHS ester. Synonyms: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 1-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]-1H-pyrrole-2,5-dione; 2,5-Dioxo-1-pyrrolidinyl 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoate. Grade: ≥98%. CAS No. 1433997-01-3. Molecular formula: C15H18N2O8. Mole weight: 354.31.
Maltol
Maltol is a fragrance molecule used in flavor enhancers and fragrances. Uses: Antioxidant. Synonyms: 3-Hydroxy-2-methyl-4H-pyran-4-one; 2-Methyl-3-hydroxy-4-pyrone; 2-Methyl-3-hydroxypyran-4-one; 3-Hydroxy-2-methyl-1,4-pyrone; Larixic Acid; Larixin; Palatone; Veltol. Grade: 98%. CAS No. 118-71-8. Molecular formula: C6H6O3. Mole weight: 126.11.
Mangiferin
Mangiferin is a natural xanthone isolated from Anemarrhena asphodeloides Bunge rhizome. The distinctive gold-orange fluorescence of Mangiferin under ultraviolet light , it has been used to aid in the chromatographic identification of hybrid Aspleniums. Uses: Antidiabetic, anthelminthic, antiallergic. Synonyms: 2-b-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-Xanthen-9-one; Mangiferin; Alpizarine. Grade: 95%. CAS No. 4773-96-0. Molecular formula: C19H18O11. Mole weight: 422.34.
MA-PEG4-vc-PAB-DMEA-duocarmycin DM
MA-PEG4-vc-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Synonyms: Mal-PEG4-vc-PAB-DMEA-duocarmycin DM. Grade: 95%. Molecular formula: C68H89ClN12O17. Mole weight: 1381.98.
MA-PEG4-vc-PAB-DMEA-duocarmycin SA
MA-PEG4-vc-PAB-DMEA-duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Synonyms: Mal-PEG4-vc-PAB-DMEA-duocarmycin SA. Grade: 95%. Molecular formula: C67H87ClN12O21. Mole weight: 1431.94.
Marmin
Marmin is a natural coumarin found in the herbs of Citrus maxima. By interfering histamine receptor, Marmin can inhibit the histamine release from mast. Marmin can also inhibit contraction of the guinea-pig tracheal smooth muscle. Synonyms: (R)-(+)-Marmin; 7-[[(6R,2E)-6,7-Dihydroxy-3,7-dimethyl-2-octenyl]oxy]-2H-1-benzopyran-2-one. Grade: >98%. CAS No. 14957-38-1. Molecular formula: C19H24O5. Mole weight: 332.4.
Marmin acetonide
Marmin acetonide is a natural coumarin found in the peels of Citrus grandis (L.) Osbeck. Synonyms: 7-[[(2E)-3-Methyl-5-[(4R)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl]-2-pentenyl]oxy]-2H-1-benzopyran-2-one. Grade: >98%. CAS No. 320624-68-8. Molecular formula: C22H28O5. Mole weight: 372.5.
Matrine
Matrine ((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist. Uses: Anticancer. Synonyms: Matridin-15-one; Matrine; NSC 146051; NSC146051; NSC-146051. Grade: >98%. CAS No. 519-02-8. Molecular formula: C15H24N2O. Mole weight: 248.36.
Mauritianin
Mauritianin is a compound of the flavonoid class found in the herbs of Hypericum japonicum Thunb. Mauritianin is a topoisomerase I inhibitor. Synonyms: 5,7-dihydroxy-3-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy]oxan-2-yl]oxy-2-(4-hydroxyphenyl)chromen-4-one. Grade: >98%. CAS No. 109008-28-8. Molecular formula: C33H40O19. Mole weight: 740.664.