BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Prasugrel Metabolite R | A metabolite of Prasugrel. Prasugrel is a platelet inhibitor and an irreversible antagonist of P2Y12ADP receptors that prevents the formation of blood clots. It was appoved for the treatment of acute coronary syndrome (ACS), and some cardiovascular diseasess in combination with Aspirin. Synonyms: (2Z)-2-[1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-sulfanylpiperidin-3-ylidene]acetic acid; Prasugrel Metabolite R-138727. Grades: 95%. CAS No. 204204-73-9. Molecular formula: C18H20FNO3S. Mole weight: 349.42. |  |
| Pratensein | Pratensein is found in he herbs of Trifolium pratense L. Synonyms: 3'-hydroxybiochanin A; 5,7,3'-trihydroxy-4'-methoxyisoflavone. Grades: > 95%. CAS No. 2284-31-3. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| PRD-125 | PRD-125 is a potent SOAT2 inhibitor derived from pyripyropene A. Study shows that PRD-125 can suppress cholesterol diet-induced fatty liver progression in dose dependent manner and reduce the risk of atherosis in rabbit model. Uses: The potential treatment of atherosis. Synonyms: PRD-125; PRD 125; PRD125. | |
| PRE-084 | PRE-084 Hydrochloride is a selective sigma-1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). PRE-084 is selective for PCP receptors (IC50 > 100000 nM) and several other receptor systems. It exhibits neuroprotective property. Synonyms: 2-(4-Morpholinyl)ethyl 1-phenylcyclohexanecarboxylate hydrochloride; PRE-084 (hydrochloride); PRE 084 (hydrochloride); PRE084 (hydrochloride). Grades: 98%. CAS No. 138847-85-5. Molecular formula: C19H27NO3. Mole weight: 317.4. | |
| pre-Calcitriol PTAD Adduct | Impurity C of Calcitriol is the impurity C of Calcitriol, which is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Synonyms: 1H,5H-Cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione, 11-(3,5-dihydroxy-2-methyl-1-cyclohexen-1-yl)-4a,6,6a,7,8,9,9a,11-octahydro-7-(5-hydroxy-1,5-dimethylhexyl)-6a-methyl-2-phenyl-, [4aR-[4aα, 6aα, 7α(R*), 9aβ, 11α(3S*, 5R*)]]- (9CI). Grades: >98%. CAS No. 86307-44-0. Molecular formula: C35H49N3O5. Mole weight: 591.78. | |
| Pregnenolone Carbonitrile | Pregnenolone carbonitrile (PCN) is a derivative of pregnenolone and acts as an agonist of the rodent pregnane X receptor (PXR). Synonyms: PCN; Pregnenolone 16α-carbonitrile; SC-4674; (3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile. Grades: ≥98%. CAS No. 1434-54-4. Molecular formula: C22H31NO2. Mole weight: 341.5. | |
| Prezatide Copper | GHK-Cu stimulates the production of collagen and is used in the anti-aging products. GHK-Cu also exhibits therapeutic effect on hair loss. Synonyms: Prezatide Copper; GHK copper; CG-copper peptide; [n2-(N-Glycyl-L-histidyl)-L-lysinato(2-)]copper. CAS No. 89030-95-5. Molecular formula: C14H21CuN6O4. Mole weight: 400.91. | |
| PRL-3 Inhibitor | PRL-3 inhibitor is a cell-permeable benzylidene rhodamine that inhibits phosphatase of regenerating liver 3 (PRL-3). It reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay. Synonyms: BR-1; P0108; Phosphatase of Regenerating Liver 3 Inhibitor; PTP4A3 Inhibitor; 1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene rhodanine. Grades: ≥98%. CAS No. 893449-38-2. Molecular formula: C17H11Br2NO2S2. Mole weight: 485.2. | |
| PRMT3 inhibitor 1 | PRMT3 inhibitor 1 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3; IC50 value of 1.6 μM for inhibition of full length PRMT3 in a radioactivity-based assay). Synonyms: PRMT3 inhibitor 1; PRMT 3 inhibitor 1; PRMT-3 inhibitor 1. Grades: 99%. CAS No. 1340875-03-7. Molecular formula: C15H18N4OS. Mole weight: 302.39. | |
| PRN1371 | PRN1371 is an irreversible covalent FGFR1-4 kinase inhibitor. Synonyms: 6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-one. CAS No. 1802929-43-6. Molecular formula: C26H30Cl2N6O4. Mole weight: 561.46. | |
| Proadrenomedullin (N-20) (human) trifluoroacetate salt | Proadrenomedullin (N-20) (PAMP-20) is an endogenous peptide and an agonist of the G protein-coupled orphan receptor MRGPRX2 that inhibits forskolin-induced cAMP accumulation in CHO cells expressing the human receptor with an EC50 value of 251 nM. Synonyms: ?PAMP-20; Proadrenomedullin N-Terminal 20; ProAM-N20. Grades: ≥95%. Molecular formula: C112H178N36O27·xCF3COOH. Mole weight: 2460.84. | |
| Probucol | Enhances selective uptake of HDL-associated cholesteryl esters. Synonyms: Lorelco. Grades: >98%. CAS No. 23288-49-5. Molecular formula: C31H48O2S2. Mole weight: 516.84. | |
| Procyanidin B1 | Procyanidin B1 is a procyanidin dimer found in Cinnamomum verum, in Uncaria guianensis, and in Vitis vinifera or in peach. Procyanidin B1 (PB1) inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with 50% effective concentrations of 29 and 15 μM, respectively. No inhibitory effects were observed in each component of PB1. PB1 does not interfere with viral entry or receptor expression, but inhibits HCV RNA synthesis in a dose-dependent manner. Uses: Antioxidant;anti-inflammatory. Synonyms: Proanthocyanidin B1; Endotelon; Procyanidin dimer B1. Grades: >98%. CAS No. 20315-25-7. Molecular formula: C30H26O12. Mole weight: 578.52. | |
| Procyanidin C2 | Procyanidin C2 is a proanthocyanidin trimer isolated from grape seeds (Vitis vinifera), in Pinus radiata, in Potentilla viscosa and so on. Grades: > 95%. CAS No. 37064-31-6. Molecular formula: C45H38O18. Mole weight: 866.77. | |
| Procyanidol B4 | Procyanidol B4 is a flavonoid with antioxidant and anti-inflammatory properties. Synonyms: Procyanidin B4. Grades: 98%. CAS No. 29106-51-2. Molecular formula: C30H26O12. Mole weight: 578.5. | |
| Progesterone | Progesterone is a natural steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Uses: Endogenous progesterone receptor (pr) agonist. Synonyms: Progestin; Lutren; Lutein; Flavolutan; Corporin; Luteal Hormone; 4-Pregnene-3,20-Dione; Pregn-4-ene-3,20-dione; Agolutin; Bio-luton; Crinone; Cyclogest; Duraprogen; Endometrin; Estima; Flavolutan; Fologenon; Gesterol; Gestormone; Glanducorpin; Hormoflaveine; Hormoluton; Lutromone; Microgest; Minagest; Nalutron; NSC 64377; NSC 9704; Percutacrine Luteinique; Progesterol; Protormone; Sincrogest; Syngesterone; Syntolutan; U 3672; Utrogest; Utrogestan; Vitarrine; Δ4-Pregnene-3,20-dione. Grades: >98%. CAS No. 57-83-0. Molecular formula: C21H30O2. Mole weight: 314.46. | |
| Prohexadione calcium | Prohexadione calcium (CAS# 127277-53-6 ) is a useful research chemical. Synonyms: Prohexadione-Calcium; calcium 3-oxido-5-oxo-4-propionylcyclohex-3-enecarboxylate; ProCa. Grades: 95 %. CAS No. 127277-53-6. Molecular formula: C20H22CaO10. Mole weight: 462.46. | |
| ProINDY | ProINDY, the prodrug form of INDY, is a cell permeable ATP-competitive DYRK1A/B inhibitor. Synonyms: TG007; TG-007; TG 007; (1Z)-1-(5-Acetyloxy3-ethyl-2(3H)-benzothiazolylidene)-2-propanone. Grades: ≥98% by HPLC. CAS No. 719277-30-2. Molecular formula: C14H15NO3S. Mole weight: 277.34. | |
| Prontosil | Prontosil is one of the earliest antimicrobial drugs that was widely used in mid-20th century. It has an effect against gram-positive cocci but not against enterobacteria. Synonyms: Sulfamidochrysoidine; Rubiazol; Prontosil rubrum; 4-[ (2, 4-diaminophenyl) diazenyl]benzenesulfonamide. CAS No. 103-12-8. Molecular formula: C12H13N5O2S. Mole weight: 291.329. | |
| Propagermanium | Propagermanium is an organometallic compound of germanium that is sold as an alternative medicine for the treatment of Hepatitis B under the development of Astellas Pharma and Sanwa Kagaku Kenkyusho. Uses: Hepatitis b. Synonyms: Carboxyethylgermanium sesquioxide; Ge 132; 14C-Proxigermanium; Bis(2-carboxyethylgermanium(IV) sesquioxide). Grades: 98.5 - 101.5% (Titration). CAS No. 126595-07-1. Molecular formula: C6H10Ge2O7. Mole weight: 339.40. | |
| Propanil | Propanil is a widely used contact herbicide mainly used to control weed growth in rice fields. Uses: A widely used herbicide. Synonyms: FW 734; FW734; FW-734; KEM-RAY;N-(3,4-Dichlorophenyl)propanamide. Grades: ≥95%. CAS No. 709-98-8. Molecular formula: C9H9Cl2NO. Mole weight: 218.08. | |
| Propargyl a-D-mannopyranoside | Propargyl α-D-mannopyranoside, a carbohydrate derivative, has been identified as a critical component in glycan conjugate synthesis for chemical biology and drug development. This versatile compound exhibits excellent reactivity with a variety of glycosyl transferases, facilitating the production of numerous bioactive compounds. It is thus a valuable tool in applied chemistry, offering a range of opportunities for drug discovery and development through its unique structural properties. Synonyms: Propargyl alpha-D-mannopyranoside; (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-(prop-2-yn-1-yloxy)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 854262-01-4. Molecular formula: C9H14O6. Mole weight: 218.20. | |
| (±)-Propionylcarnitine chloride | (±)-Propionylcarnitine chloride is the homolog of acetylcarnitine chloride, which is used in the synthetic preparation of pure esters of dl-carnitine chloride with fatty acids. Synonyms: (R)-3-carboxy-N,N,N-trimethyl-2-(propionyloxy)propan-1-aminium chloride. Grades: ≥95%. CAS No. 18828-58-5. Molecular formula: C10H20ClNO4. Mole weight: 253.73. | |
| Prostaglandin F2α (tromethamine salt) | Cas No. 38562-01-5. | |
| Protein degrader 1 hydrochloride | Protein degrader 1 hydrochloride is a building block used in the synthesis of PROTAC for the recruitment of the von Hippel-Lindau (VHL) protein. Synonyms: (S,R,S)-AHPC hydrochloride; (2S,4R)-1-((S)-2-Amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride. Grades: ≥98%. CAS No. 1448189-80-7. Molecular formula: C22H31ClN4O3S. Mole weight: 467.02. | |
| Protein hydrolyzates, yeast | Protein hydrolyzates, yeast is a hydrolyzed product of yeast cells, which is obtained by autolysis or hydrolysis with additional enzymes. Hydrolyzed yeast products contain a large number of amino acids, small peptides, rich B vitamins, glutathione and nucleotide substances. It is mainly used as an antioxidant in cosmetics and skin care products, controlling oil and resisting fat overflow. Synonyms: Hydrolyzed yeast protein; Proteins, yeast, hydrolysate; Yeast protein hydrolysate. Grades: 95%. CAS No. 100684-36-4. | |
| Prothioconazole | Prothioconazole is an antifungal agent that can be used as agricultural fungicide and herbicide. Synonyms: 3H-1,2,4-Triazole-3-thione, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-; 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione; Acceleron DX 342; JAU 6476; Joao; Proline (fungicide); Proline 275; Proline 480SC; Redigo; Rudis. Grades: >95%. CAS No. 178928-70-6. Molecular formula: C14H15Cl2N3OS. Mole weight: 344.26. | |
| PROTO-1 | PROTO-1, a benzothiophene carboxamide, shows significant protection of hair cells over a broad range of neomycin concentrations, from 25 μM to 400 μM. Synonyms: 2-[(4-chlorophenyl)carbamoylamino]-6-ethyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamidePROTO-1; PROTO1; PROTO 1ST50928294CBMicro_046627AC1LLLR7Opr ea1_608416SCHEMBL2682306. CAS No. 312951-85-2. Molecular formula: C17H19ClN4O2S. Mole weight: 378.88. | |
| PRT062607 | PRT062607 is a highly specific and potent inhibitor of spleen tyrosine kinase (Syk) (IC50 = 1-2 nM). Synonyms: PRT-062607; PRT 062607; P505-15; PRT-2607; PRT 2607; PRT2607; BIIB 057; 4-((3-(2H-1,2,3-triazol-2-yl)phenyl)amino)-2-(((1R,2S)-2-aminocyclohexyl)amino)pyrimidine-5-carboxamide; 5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-; 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide. Grades: >98%. CAS No. 1370261-96-3. Molecular formula: C19H23N9O. Mole weight: 393.45. | |
| PRT062607 Hydrochloride | PRT062607 is a highly selective and orally available Syk inhibitor with IC50 of 1 nM in cell-free assays, >80-fold selective for Syk than other kinases including Fgr, Lyn, FAK, Pyk2 and Zap70. Synonyms: PRT062607 HCl; P505-15 HCl; P505-15 hydrochloride; BIIB057 HCl; BIIB057 hydrochloride; 5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, hydrochloride (1:x); 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride. Grades: ≥95%. CAS No. 1439908-97-0. Molecular formula: C19H23N9O.xHCl. Mole weight: 393.45 (free base). | |
| Prucalopride N-Oxide | A metabolite of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Synonyms: N-Oxo Prucalopride; 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-1-oxido-4-piperidinyl]-7-benzofurancarboxamide. Grades: > 95%. CAS No. 1900715-98-1. Molecular formula: C18H26ClN3O4. Mole weight: 383.88. | |
| Przewalskinic acid A | Przewalskinic acid A is found in the Salvia przewalskii Maxim herb. Synonyms: Przewalskinic acid A; 136112-75-9; (2R,3R)-4-[(E)-2-carboxyethenyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid; 7-Epiblechnic acid; HY-N5057. Grades: >98%. CAS No. 136112-75-9. Molecular formula: C18H14O8. Mole weight: 358.3. | |
| PS 47 | PS 47 is an inactive E-isomer of the PDK1 activator PS 48. In combination with PS 48, PS 47 can be used as a negative control. Synonyms: PS-47; PS 47; PS47; (E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid. Grades: 99%. CAS No. 1180676-33-8. Molecular formula: C17H15ClO2. Mole weight: 286.75. | |
| PSB 06126 | PSB 06126, an anthraquinone derivative, is a nucleoside triphosphate diphosphohydrolase 3 (NTPDase 3) inhibitor. It was reported to inhibit rat NTPDase 3 at low micromolar concentrations and display selectivity over NTPDase 1 and NTPDase 2. Synonyms: PSB 06126; PSB06126; PSB-06126;1-Amino-4-(1-naphthyl)aminoanthraquinone-2-sulfonic acid sodium salt. Grades: ≥98% by HPLC. CAS No. 1052089-16-3. Molecular formula: C24H15N2NaO5S. Mole weight: 466.44. | |
| PSB 069 | PSB 069 is a non-selective inhibitor of nucleoside triphosphate diphosphohydrolases 1,2,3 (NTPDases 1,2,3) (Ki = 15.7, 18.0, 16.4 μM, respectively). It was reported to inhibit rat NTPDases 1, 2 and 3 with similar potencies. Synonyms: PSB 069; PSB069; PSB-069; 1-Amino-4-(4-chlorophenyl)aminoanthraquinone-2-sulfonic acid sodium salt. Grades: ≥98% by HPLC. CAS No. 78510-31-3. Molecular formula: C20H12N2O5ClSNa. Mole weight: 450.83. | |
| PSEM 308 hydrochloride | PSEM 308 is an agonist of pharmacologically selective actuator module (PSAM) that activates PSAML141F-GlyR chimeric ion channels. Synonyms: PSEM-308 hydrochloride; PSEM 308 HCl; PSEM-308 HCl; 5-Methyl-5, 8, 9, 10, 11a, 12-hexahydro-4H-8, 11-ethanopyrido[3', 2':3, 4]diazepino[6, 7, 1-hi]indole hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C17H21N3·HCl. Mole weight: 303.83. | |
| PSEM 89S | PSEM 89S is a PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist (EC50 values are 3.4 and 2.2 μM, respectively). It activates cortical neurons expressing PSAML141F,Y115F-5-HT3 chimeric ion channels and inhibits activity of neurons expressing PSAML141F-GlyR in vitro. Synonyms: N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide trifluoroacetate. Grades: ≥98% by HPLC. CAS No. 1336913-03-1. Molecular formula: C16H22N2O3·CF3CO2H. Mole weight: 404.38. | |
| Pseudoginsenoside Rh2 | Pseudoginsenoside Rh2, a ginseng-derived natural compound, has garnered significant attention for its potential anti-cancer properties against breast and liver cancers. Beyond its anti-cancer benefits, it also demonstrates significant neuroprotective effects, which prove promising for the treatment of neurodegenerative diseases like Alzheimers and Parkinsons. Its diverse applications in medicine suggest a broad range of future therapeutic opportunities. Synonyms: (3b,12b,20E)-12,25-Dihydroxydammar-20(22)-en-3-yl b-D-glucopyranoside; Ginsenoside Rh10. Grades: >98%. CAS No. 1370264-16-6. Molecular formula: C36H62O8. Mole weight: 622.87. | |
| Pseudoginsenoside-RT5 | Pseudoginsenoside-RT5 is extracted from the roots of Panax ginseng C. A. Mey. It has antibacterial, antitumor and anti malaria effects. It promotes nerve growth and improves cognitive ability. Synonyms: (3beta,6alpha,12beta,24R)-20,24-Epoxy-3,12,25-trihydroxydammaran-6-yl beta-D-glucopyranoside; 24(R)-Pseudoginsenoside rt(5); b-D-Glucopyranoside, (3b,6a,12b,24R)-20,24-epoxy-3,12,25-trihydroxydammaran-6-yl. Grades: >98%. CAS No. 98474-78-3. Molecular formula: C36H62O10. Mole weight: 654.9. | |
| Pseudolaric Acid A | Pseudolaric acid A can inhibit the growth of particular cell types within the disease-oriented human cancer cell line panels. Synonyms: (2E,4E)-5-[(4aS)-4a-(acetyloxy)-3,7-dimethyl-1-oxo-3,4,4a,5,6,9-hexahydro-4,9a-ethanocyclohepta[c]pyran-3(1H)-yl]-2-methylpenta-2,4-dienoic acid. Grades: >98%. CAS No. 82508-32-5. Molecular formula: C22H28O6. Mole weight: 388.5. | |
| Pseudolaric acid A-O-beta-D-glucopyranoside | Pseudolaric acid A-O-beta-D-glucopyranoside can be found in the root bark of Pseudolarix amabilis. Synonyms: Pseudolaricid A-O-β-D-glucopyranoside; Pseudolaric acid A beta-D-glucoside. Grades: >98%. CAS No. 98891-44-2. Molecular formula: C28H38O11. Mole weight: 550.6. | |
| Pseudolaric acid B-O-beta-D-glucopyranoside | Pseudolaric acid B-O-beta-D-glucopyranoside can be found in the root bark of Pseudolarix amabilis. Synonyms: Pseudolaric acid B-glucopyranoside; Pseudolaric acid B beta-D-glucoside. Grades: >98%. CAS No. 98891-41-9. Molecular formula: C29H38O13. Mole weight: 594.6. | |
| Pseudolaric Acid C | Pseudolaric Acid C usually can be isolated from the root bark of Pseudolarix amabilis. Synonyms: (3R,4R,4aS,9aR)-rel-3-[(1E,3E)-4-Carboxy-1,3-pentadienyl]-3,4,4a,5,6,9-hexahydro-4a-hydroxy-3-methyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-7-carboxylic acid 7-methyl ester; Deacetylpseudolaric acid B. Grades: >98%. CAS No. 82601-41-0. Molecular formula: C21H26O7. Mole weight: 390.4. | |
| PseudoUridine 5'-monophosphate Sodium salt | A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Synonyms: Pseudouridylic acid sodium salt; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol sodium salt; pseudouridine 5'-phosphate sodium salt; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione sodium salt; 5-b-D-Ribofuranosyluracil 5'-phosphate sodium salt; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate, sodium salt. Molecular formula: C9H13N2O9P.xNa. Mole weight: 324.18 (free acid). | |
| PseudoUridine 5'-Triphosphate Sodium | PseudoUridine 5'-Triphosphate Sodium is a compound, finding extensive employment in the exploration of RNA modifications and nucleotide analogs. Synonyms: Sodium ((2R,3S,4R,5S)-5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-2, 4 (1H, 3H) pyrimidinedione Sodium salt; Pseudo UTP Sodium salt; 5-Ribosyl Uraci Sodium salt; 5-β-D-Ribofuranosyluracil 5'-Triphosphate Sodium Salt; Pseudouridine Triphosphate Sodium Salt; PseudoUridine 5'-Triphosphate; Pseudo UTP; Pseudo-UTP. Grades: ≥95%. Molecular formula: C9H15N2O15P3.xNa. Mole weight: 484.14 (free acid). | |
| PTC-028 | PTC-028 is an orally bioavailable inhibitor of BMI-1. It decreases BMI-1 levels and induces apoptosis in ovarian cancer. Synonyms: PTC028; PTC 028; 6-(5,6-Difluoro-2-methylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine. CAS No. 1782970-28-8. Molecular formula: C19H12F5N5. Mole weight: 405.32. | |
| PTC-209 hydrobromide | Polycomb complex protein BMI-1 is a polycomb ring finger oncogene that regulates the p16 and p19 cell cycle inhibitor genes. It is necessary for efficient self-renewing cell divisions of stem cells in several tissues and can be over-expressed in tumors. PTC-209 is a BMI-1 inhibitor (IC50 = ~ 0.5 μM) that irreversibly impairs colorectal cancer-initiating cell (CIC) growth. It reduces tumor growth in CIC xenograft assays and abrogates colorectal cancer cell self-renewal in vivo, reducing their tumorigenic potential. Synonyms: PTC-209; PTC 209; PTC209 Hydrobromide; N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-amine hydrobromide. Grades: >98%. CAS No. 1217022-63-3. Molecular formula: C17H14Br3N5OS. Mole weight: 576.1. | |
| p-tert-Butoxycarbonyloxystyrene | p-tert-Butoxycarbonyloxystyrene, an important monomer within the biomedical industry, is utilized in the synthesis of copolymers such as poly(styrene-alt-maleic anhydride). Due to its compatibility with therapeutic drugs, these copolymers are currently under investigation as potential therapies for a range of ailments, from cancer to inflammatory disorders. Synonyms: 1,1-dimethylethyl4-ethenylphenylcarbonate; 4-boc-styrene; c-1566; carbonic acid, 1,1-dimethylethyl 4-ethenylphenylester; TBSM; Tert-butyl 4-vinylphenyl carbonate. Grades: 95%. CAS No. 87188-51-0. Molecular formula: C13H16O3. Mole weight: 220.26. | |
| PTP1B-IN-1 | PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor. Synonyms: PTP1B-IN-1; PTP1B IN 1; PTP1BIN1; PTP1B inhibitor 1; PTP1B-inhibitor-1. Grades: >98%. CAS No. 612530-44-6. Molecular formula: C8H8N2O3S. Mole weight: 212.23. | |
| PTP1B Inhibitor | PTP1B inhibitor is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B), which is involved in cell signaling relevant to diabetes, obesity, and cancer. Synonyms: Protein Tyrosine Phosphatase 1B Inhibitor; FRJ; 3-(3,5-Dibromo-4-hydroxy-benzoyl)-2-ethyl-benzofuran-6-sulfonicacid-(4-(thiazol-2-ylsulfamyl)-phenyl)-amide. Grades: ≥98%. CAS No. 765317-72-4. Molecular formula: C26H19Br2N3O7S3. Mole weight: 741.5. | |
| PTP Inhibitor III | PTP Inhibitor III is a cell-permeable inhibitor of protein tyrosine phosphatase (PTP), a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. It binds to the catalytic domain of SHP-1 with Ki value of 184 μM. Synonyms: α-Bromo-4-(carboxymethoxy)acetophenone; Protein Tyrosine Phosphatase Inhibitor III; 2-[4-(2-Bromoacetyl)phenoxy]acetic acid. Grades: ≥95%. CAS No. 29936-81-0. Molecular formula: C10H9BrO4. Mole weight: 273.1. | |
| PTP Inhibitor IV | PTP inhibitor IV is an uncharged, 1,4-di-substituted, phenyl-linked bis-trifluoromethylsulfonamido phosphate mimetic that acts as a reversible, competitive, and active-site directed inhibitor of SHP-2, PTP1B, PTP-ε, PTP-Meg-2, PTP-σ, PTP-β, and PTP-μ (IC50s = 1.8, 2.5, 8.4, 13, 20, 6.4, and 6.7 μM, respectively). Synonyms: Protein Tyrosine Phosphatase Inhibitor IV; Bis(4-Trifluoromethylsulfonamidophenyl)-1,4-diisopropylbenzene; 1, 1, 1-trifluoro-N-[4-[2-[4-[2-[4- (trifluoromethylsulfonylamino) phenyl]propan-2-yl]phenyl]propan-2-yl]phenyl]methanesulfonamide. Grades: ≥98%. CAS No. 329317-98-8. Molecular formula: C26H26F6N2O4S2. Mole weight: 608.6. | |
| PTZ-343 | It acts as an HRP chemiluminescence enhancer. In the configuration of chemiluminescence substrate A/B solution, the addition of a certain amount of enhancer is helpful to enhance the luminescence intensity and sensitivity. Uses: For research use only. Synonyms: Sodium 3-(10H-Phenothiazin-10-yl)?propane-1-sulfonate; 10H-Phenothiazine-10-propanesulfonic Acid, Sodium Salt; 3-(10'-Phenothiazinyl)propane-1-sulfonate Sodium; 3-(phenothiazin-10-yl)propane-1-sulfonate Sodium; PTZ 343; PTZ343. Grades: 98% by HPLC. CAS No. 101199-38-6. Molecular formula: C15H14NNaO3S2. Mole weight: 343.40. | |
| PU 23 | PU 23 is a multidrug resistance protein (MRP) 4 inhibitor that sensitizes MRP4-overexpressing cells to the anticancer agent 6-Mercaptopurine. Synonyms: N- [ [ [4- [ [ (Phenylmethyl) amino] sulfonyl] phenyl] amino] thioxomethyl] benzamide. Grades: ≥98% by HPLC. CAS No. 817635-93-1. Molecular formula: C21H19N3O3S2. Mole weight: 425.52. | |
| Pulchinenoside B | Pulchinenoside B is an extract derived from a distinct plant, acting as a remarkable natural compound widely recognized in the field of diverse ailments research. Synonyms: Anemoside B. Grades: >98%. CAS No. 135247-95-9. Molecular formula: C53H86O22. Mole weight: 1221.4. | |
| Punicalagin | Punicalagin is an ellagitannin, a type of phenolic compounds. It had a greater antifungal activity against T. rubrum. It has the potential to be developed as an alternative or supplemental agent for prevention of Salmonella infection. After being absorbed by the human body, punicalagin can be decomposed into ellagic acid under the action of human enzymes. It has excellent antioxidant properties and has been used as a food antioxidant. It is now mostly used in cosmetics. Synonyms: 2,3-(S)-hexahydroxydiphenoyl-4,6-(S,S)-gallagyl-D-glucose. Grades: >98%. CAS No. 65995-63-3. Molecular formula: C48H28O30. Mole weight: 1084.7. | |
| Purmorphamine | Purmorphamine, under the IUPAC name 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine, is a cell-permeable 6,9-trisubstituted purine which directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ).So it has been shown to activate the Hedgehog (Hh) signaling pathway which is important for regulating embryonic patterning, stem cell renewal, and tissue regeneration. In vitro: An activator of the hedgehog (Hh) signaling pathway by directly binds and activates Smoothened (in HEK293T cell:IC50= ~ 1.5 μM ). In vivo: Purmorphamine up-regulates ALP expression in human mesenchymal stem cell-based constructs on rats. Uses: Directly binds and activates smoothened (in hek293t cell:ic50= ~ 1.5 μm ); an activator of the hedgehog (hh) signaling pathway; an inducer of osteoblast differentiation (ec50= 1 μm). Synonyms: 9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine; purmorphamine; Purmorphamine; 483367-10-8; 2-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine; UNII-PB12M2F8KY; Shh Signaling Antagonist VI; PB12M2F8KY; CHEMBL1221984; CHEBI:63053; C31H32N6O2; IN1132; 9-cyclohexyl-N-[4-(morpholin-4-yl)phenyl]-2-(naphthalen-1-yloxy)-9H-purin-6-amine; 9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine; 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine; 9-Cyclohexyl-N-(4-(4-morpholinyl)phenyl)-2-(1-naphthalenyloxy)-9H-purin-6-amine; Purmorphamine [MI]; MolMap_000073; AC1NR49A; MLS006010334; SCHEMBL1548273; CTK1D4950; AOB5391; DTXSID20415293. Grades: ≥ 98.0%. CAS No. 483367-10-8. Molecular formula: C31H32N6O2. Mole weight: 520.60. | |
| PX-12 | PX-12 is an irreversible inhibitor of Trx-1 currently in clinical development as an antitumor agent. The research results suggest that the lowering of elevated levels of plasma Trx-1 in cancer patients may provide a surrogate for the inhibition of tumor Trx-1 by PX-12. Synonyms: PX12; PX 12; PX-12. CAS No. 141400-58-0. Molecular formula: C7H12N2S2. Mole weight: 188.31. | |
| PXS-5446 | PXS-5446 is a lysyl oxidase inhibitor. Study in GATA-1low mice reveals that PXS-5446 decreases fibrosis in bone marrow and spleen size. PXS-5446 is promisingly to be a novel therapy of primary myelofibrosis (PMF). Uses: Potential primary myelofibrosis (pmf) therapy. Synonyms: PXS-5446; PXS 5446; PXS5446. | |
| PYR-0222 | A useful intermediate for chemical synthesis. Uses: Pyrrole derivative. Synonyms: PYR-0222; PYR 0222; PYR0222. 3,4-Dimethyl-3-pyrrolin-2-one;1,5-Dihydro-3,4-dimethyl-2H-pyrrol-2-one. Grades: ≥98%. CAS No. 4030-22-2. Molecular formula: C6H9NO. Mole weight: 111.14. | |
| PYR-0503 | PYR-0503, a pyrrole compound, could be commonly used in production of sorts of important compounds like some anticancer drugs and porphyrins. Synonyms: 3,4-Diethyl-2-ethoxycarbonyl-5-methylpyrrole;Ethyl 3,4-diethyl-5-methyl-1H-pyrrole-2-carboxylate. Grades: 98%. CAS No. 16200-50-3. Molecular formula: C12H19NO2. Mole weight: 209.28. | |
| PYR-6921 | PYR-6921is a useful intermediate for chemical synthesis of biologically molecules. Uses: A useful intermediate. Synonyms: PYR-6921; PYR 6921; PYR6921. 1H-Pyrrole-2-carboxylic acid, 4-ethyl-3,5-dimethyl-, 1,1-dimethylethylester. Grades: ≥95%. CAS No. 31896-92-1. Molecular formula: C13H21NO2. Mole weight: 223.15. | |
| PYR-7911 | PYR-791 is an important synthetic intermediate for a lot of bio-active molecules, including porphyrins, bile pigments, photosensitizers, anticancer agents. Uses: Synthetic intermediate for a lot of bio-active molecules. Synonyms: PYR-7911; PYR 7911; PYR7911. benzyl 5-(acetoxymethyl)-3-methyl-1H-pyrrole-2-carboxylate. Grades: 98%. CAS No. 124307-91-1. Molecular formula: C16H17NO4. Mole weight: 287.31. | |
| Pyraclonil | Pyraclonil is a herbicide agent. Synonyms: Pyraclonil. Grades: >98%. CAS No. 158353-15-2. Molecular formula: C15H15ClN6. Mole weight: 314.77. | |
| Pyridazinediones-derivative-1 | It inhibits glutamate-induced contractions of isolated guineapig ileum (ED50= 2.1 μM) with potential to treat neurodegenerative disorders. Synonyms: Pyridazino[4,5-b]quinoline-1,4-dione, 7-chloro-2,3-dihydro-10-hydroxy-; 7-chloro-3,5-dihydro-2H-pyridazino[4,5-b]quinoline-1,4,10-trione. CAS No. 147493-44-5. Molecular formula: C11H6ClN3O3. Mole weight: 263.64. | |
| Pyridostatin | Pyridostatin is a G-quadruplex-interacting drug which can promote growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Synonyms: RR-82; RR82; RR 82. Grades: >98%. CAS No. 1085412-37-8. Molecular formula: C31H32N8O5. Mole weight: 596.64. | |
| Pyridostatin pentahydrochloride | Pyridostatin pentahydrochloride binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM). Synonyms: 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride. Grades: ≥98% by HPLC. CAS No. 1781882-65-2. Molecular formula: C31H32N8O5.5HCl. Mole weight: 778.94. | |
| Pyrrolidinyl diaminopyrimidine oxide | Pyrrolidinyl diaminopyrimidine oxide is a profoundly intricate compound that has exhibited excellent potential for drug development to tackle inflammation and cancer. By selectively blocking protein kinases responsible for cell proliferation and survival, it provides a vast scope for treating multiple ailments. Clinically, Pyrrolidinyl diaminopyrimidine oxide delivers remarkable results in suppressing an array of tumors and inflammation-triggering conditions of varying severity. Synonyms: 2,6-diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide; Triaminodil. Grades: 97%. CAS No. 55921-65-8. Molecular formula: C8H13N5O. Mole weight: 195.22. | |
| PZM-21 | PZM-21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM. PZM21 is an experimental opioid analgesic that is being studied for the treatment of pain. Synonyms: PZM21. Grades: ≥95%. CAS No. 1997387-43-5. Molecular formula: C19H27N3O2S. Mole weight: 361.5. | |
| Qc 1 | Qc 1 is a reversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50 ~500 nM), with no detectable inhibition of other dehydroxygenase enzymes at concentrations up to 10 mM. It induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells. Synonyms: Qc1; Qc-1; Qc 1; 1,2,3,4-Tetrahydro-4-oxo-N-(phenylmethyl)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-7-quinazolinecarboxamide; Qc1; Qc-1; Qc 1. Grades: ≥98% by HPLC. CAS No. 403718-45-6. Molecular formula: C23H16F3N3O2S. Mole weight: 455.45. | |
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