Diagnosis and staging of tumors expressing somatostatin receptors. Alternative Names: DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OL;4,7,10-TRICARBOXYMETHYL-1,4,7,10-TETRAAZA-CYCLODODECAN-1-YL-ACETYL-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-L-THREONINOL, (DISULFIDE BOND). CAS No. 204318-14-9. Product ID: PIPB-0186. Molecular formula: C65H92N14O18S2. Mole weight: 1421.65. SMILES: C[C@H]([C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)[C@@H](CC5=CC=CC=C5)NC(=O)CN6CCN(CCN(CCN(CC6)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)N[C@H](CO)[C@@H](C)O)O. Category: Peptide.
Edoxaban Tosylate
Used (in the form of its monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism. It has a role as an anticoagulant, an EC 3.4.21.6 (coagulation factor Xa) inhibitor and a platelet aggregation inhibitor. Alternative Names: Edoxaban tosilate DU-176b Edoxaban (tosylate). CAS No. 480449-71-6. Product ID: API480449716. Molecular formula: C31H38ClN7O7S2. Mole weight: 720.3. EINECS: 852-705-5. SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C. Appearance: White to Off-White Solid. Standard: Facility GMP.
EGCG
(-)-epigallocatechin 3-gallate is a gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin. It has a role as an antineoplastic agent, an antioxidant, a Hsp90 inhibitor, a neuroprotective agent, a plant metabolite, a geroprotector and an apoptosis inducer. It is a gallate ester, a polyphenol and a member of flavans. It is functionally related to a (-)-epigallocatechin. Alternative Names: (-)-Epigallocatechin gallate. Epigallocatechin gallate. Epigallocatechin 3-gallate. CAS No. 989-51-5. Product ID: PIPE-0610. Molecular formula: C22H18O11. Mole weight: 458.4. EINECS: 479-560-7. SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O. Appearance: Off-white to Light Yellow Solid Powder. Category: Natural Extract.
Egg Yolk Phosphatidylcholines
Egg Phosphatide Extract can be used to prevent and treat atherosclerosis. Alternative Names: Yokuretopauda LP. Yolk lecithin. Yolkin IP Lecithin. Phospholipids egg. CAS No. 93685-90-6. Product ID: PIE-0387. Molecular formula: C5H5ClN2. SMILES: CCCCCCCCC(=O)OC(COC(=O)CCCCCCCC=CCC=CCCCCC)COP(=O)(CC[N+](C)(C)C)[O-]. Appearance: White to Light Yellow Powder. Category: Emulsifiers.
Elacestrant
Elacestrant. Alternative Names: 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6R)-;Venadaparib Impurity 54;(6R)-6-2-ethyl(4-2-(ethylamino)ethylphenylmethyl)amino-4-methoxyphenyl-5,6,7,8-tetrahydronaphthalen-2-ol. CAS No. 722533-56-4. Product ID: API722533564. Molecular formula: C30H38N2O2. Mole weight: 458.63. EINECS: 258-984-3. SMILES: CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)[C@@H]3CCC4=C(C3)C=CC(=C4)O. Category: Small Molecule APIs.
Elagolix
Elagolix is a Gonadotropin Releasing Hormone Receptor Antagonist. The mechanism of action of elagolix is as a Gonadotropin Releasing Hormone Receptor Antagonist, and Cytochrome P450 3A Inducer, and Cytochrome P450 2C19 Inhibitor, and P-Glycoprotein Inhibitor. The physiologic effect of elagolix is by means of Decreased GnRH Secretion. Alternative Names: (R)-Elagolix. NBI-56418. UNII-5B2546MB5Z. CAS No. 834153-87-6. Product ID: API834153876. Molecular formula: C32H30F5N3O5. Mole weight: 631.6. EINECS: 824-769-4. SMILES: CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)O)C4=C(C(=CC=C4)OC)F. Category: APIs for Endometriosis.
Elagolix Sodium
Elagolix is a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist with KD of 54 pM. It is in phase III clinical trials for the treatment of endometriosis and uterine leiomyoma. Elagolix was also under investigation for the treatment of prostate cancer and benign prostatic hyperplasia, but development for these indications was ultimately not pursued. Alternative Names: Elagolix sodium salt. Orlissa. Elagolix sodium [USAN]. CAS No. 832720-36-2. Product ID: API832720362. Molecular formula: C32H29F5N3NaO5. Mole weight: 653.6. EINECS: 692-765-8. SMILES: CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)CC(C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+]. Category: APIs for Endometriosis.
Eluxadoline is an orally-active drug used to reduce symptoms of irritable bowel syndrome such as diarrhea and abdominal pain. Alternative Names: JNJ 27018966;Eluxadoline;Benzoic acid, 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(5-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxy-;CS-2329;Eluxadoline (Viberzi);5-(((S)-2-amino-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoic acid;Eluxadolin;API-Diarrhea. CAS No. 864821-90-9. Product ID: API864821909. Molecular formula: C32H35N5O5. Mole weight: 569.65. EINECS: 1592732-453-0. SMILES: CC1=CC(=CC(=C1C[C@@H](C(=O)N(CC2=CC(=C(C=C2)OC)C(=O)O)[C@@H](C)C3=NC=C(N3)C4=CC=CC=C4)N)C)C(=O)N. Appearance: White to Off-White Solid. Category: Antidiarrheal APIs.
Elvitegravir
Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Alternative Names: GS-9137. JTK-303. Vitekta. CAS No. 697761-98-1. Product ID: API697761981. Molecular formula: C23H23ClFNO5. Mole weight: 447.9. EINECS: 691-248-4. SMILES: CC(C)C(CO)N1C=C(C(=O)C2=C1C=C(C(=C2)CC3=C(C(=CC=C3)Cl)F)OC)C(=O)O. Appearance: Off-White to Pale Yellow Solid. Category: Antivirus APIs.
Emamectin Benzoate
Emamectin benzoate (Proclaim) is an avermectin class insecticide developed for the control of lepidopteron insects. This class of pesticide consists of homologous semi-synthetic macrolides that are derived from the natural fermentation products of Streptomyces bacteria. It kills insects by disrupting neurotransmitters, causing irreversible paralysis. Alternative Names: Emamectin benzoate. Emamectin. 137512-74-4. MK-244. CAS No. 155569-91-8. Product ID: API155569918. Molecular formula: C56H81NO15. Mole weight: 1008.2. EINECS: 605-015-1. SMILES: CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)NC)OC)OC)\C)C.C1=CC=C(C=C1)C(=O)O. Appearance: White to off-white powder. Category: Active Pharmaceutical Ingredients.
Emodin
Emodin has antibacterial, antineoplastic and cathartic activity. Alternative Names: 1,3,8-TRIHYDROXY-6-METHYL-9-10-ANTHRACENEDIONE;1,3,8-TRIHYDROXY-6-METHYLANTHRAQUINONE;6-METHYL-1,3,8-TRIHYDROXYANTHRAQUINONE;6-METHYL-1,3,8-TRIHYDROXYANTHROQUINONE;9,10-ANTHRACENEDIONE, 1,3,8-TRIHYDROXY-6-METHYL-. CAS No. 518-82-1. Product ID: PIPE-0348. Molecular formula: C15H10O5. Mole weight: 270.24. EINECS: 208-258-8. SMILES: CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O. Appearance: Powder. Standard: EP. Category: Natural Extract.
Empagliflozin
It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies, for the management of type 2 diabetes mellitus. Alternative Names: JARDIANCE. BI 10773. BI10773. CAS No. 864070-44-0. Product ID: API864070440. Molecular formula: C23H27ClO7. Mole weight: 450.9. EINECS: 620-176-8. SMILES: C1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl. Appearance: White Solid. Category: Active Pharmaceutical Ingredients.
Enalapril Maleate
Enalapril Maleate is an angiotensin-converting enzyme inhibitor. CAS No. 76095-16-4. Product ID: API76095164. SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O.C(=C\C(=O)O)\C(=O)O. Category: Active Pharmaceutical Ingredients.
Enoxacin
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent that is structurally related to NALIDIXIC ACID. Alternative Names: Enoxacin Sesquihydrate. Enoxacin hydrate. I9CD31N8WB. 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid;trihydrate. CAS No. 84294-96-2. Product ID: API84294962. Molecular formula: C30H40F2N8O9. Mole weight: 694.7. SMILES: CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O.CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O.O.O.O. Appearance: Solid powder. Category: Antibacterial APIs.
Enoxaparin Sodium
As an anticoagulant/antithrombotic agent, enoxaprin's mechanism of action is similar to that of heparin, although it exhibits a higher ratio of anti-Factor Xa to anti-Factor IIa activity. This agent also has anti-inflammatory properties, inhibiting monocyte adhesion to tumor necrosis factor alpha- or lipopolysaccharide-activated endothelial cells. Compared to unfractionated heparins, the use of enoxaparin is associated with lower incidences of osteoporosis and heparin-induced thrombocytopenia. Alternative Names: Enoxaparin Sodium (Preservative Free). Lovenox (preservative free). Anoxaparine. CAS No. 679809-58-6. Product ID: API679809586. Molecular formula: C42H59N3Na4O35S2. Mole weight: 1322. Standard: USP/EP/BP/IP.
Enrofloxacin
A fluoroquinolone antibacterial and antimycoplasma agent that is used in veterinary practice. Alternative Names: Baytril. Enrofloxacine. CFPQ. CAS No. 93106-60-6. Product ID: API93106606. Molecular formula: C19H22FN3O3. Mole weight: 359.4. EINECS: 618-911-2. SMILES: CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F. Appearance: Pale yellow crystals. Category: Antibacterial APIs.
Entecavir Monohydrate
A synthetic analogue of 2'-deoxyguanosine, entecavir is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. It is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. Enteclavir is used for the treatment of chronic hepatitis B. It has a role as an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor and an antiviral drug. Alternative Names: Entecavir hydrate. entecavir monohydrate. Entecavir (monohydrate). Entecavir hydrate (JAN). CAS No. 209216-23-9. Product ID: API209216239. Molecular formula: C12H17N5O4. Mole weight: 295.29. EINECS: 606-668-5. SMILES: C=C1C(CC(C1CO)O)N2C=NC3=C2N=C(NC3=O)N.O. Appearance: White Powder. Category: Antivirus APIs.
ent-Ezetimibe
The lipid-lowering drug, the first and only cholesterol absorption inhibitor, effectively reduces intestinal cholesterol absorption and lowers plasma cholesterol levels as well as hepatic cholesterol stores through selective inhibition of small intestinal cholesterol transporter proteins. Alternative Names: (3S,4R)-1-(4-Fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. FST3D70Q0D. (3S,4R)-1-(4-FLUOROPHENYL)-3-[(3R)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-(4-HYDROXYPHENYL)AZETIDIN-2-ONE. CAS No. 1376614-99-1. Product ID: API1376614991. Molecular formula: C24H21F2NO3. Mole weight: 409.4. SMILES: C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O. Standard: USP/BP/EP. Category: Lipid-Lowering APIs.
Enzalutamide
Used for the treatment of of metastatic castration-resistant prostate cancer. It has a role as an antineoplastic agent and an androgen antagonist. Alternative Names: MDV3100 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide. CAS No. 915087-33-1. Product ID: API915087331. Molecular formula: C21H16F4N4O2S. Mole weight: 464.4. EINECS: 805-022-1. SMILES: CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C. Standard: Facility GMP. Category: Anti-Tumor APIs.
Epalrestat
Epalrestat is an orally available, a non-competitive, reversible inhibitor of aldose reductase (AR), with potential antineoplastic, antioxidant, and anti-inflammatory activities. Alternative Names: Kinedak. Epalrestatum. Epalrestat [INN]. CAS No. 82159-09-9. Product ID: API82159099. Molecular formula: C15H13NO3S2. Mole weight: 319.4. EINECS: 675-018-0. SMILES: C/C(=C\C1=CC=CC=C1)/C=C\2/C(=O)N(C(=S)S2)CC(=O)O. Appearance: Red Solid. Category: Anti-Tumor APIs.
Epiandrosterone
It has a role as an androgen and a human metabolite. It is a 17-oxo steroid, a 3beta-hydroxy steroid and an androstanoid. It is functionally related to a 5alpha-androstane. Alternative Names: trans-Androsterone. Isoandrosterone. iso-Androsterone. CAS No. 481-29-8. Product ID: INT481298. Molecular formula: C19H30O2. Mole weight: 290.4. EINECS: 207-563-3. SMILES: C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O. Category: Intermediates.
epicatechin gallate
(-)Epicatechin gallate is an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. CAS No. 1257-08-5. Product ID: API1257085. Mole weight: 442.37. SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O. Appearance: white powder. Category: Active Pharmaceutical Ingredients.
epigallocatechin
(-)-Epigallocatechin is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. CAS No. 970-74-1. Product ID: API970741. Mole weight: 306.267. SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O. Appearance: white powder. Category: Active Pharmaceutical Ingredients.
(-)-epigallocatechingallate
Tea polyphenol, also called green tea extract, is a chemical compound, such as flavanoids and tannins, found naturally in tea. These chemical compounds are believed to be beneficial to human health, and they are the basis of many claims made about the health benefits of tea. Polyphenols are powerful antioxidants, which can reduce the risk of developing coronary artery disease and a number of other health problems. The compounds found in tea have also been linked with cancer reduction. Tea polyphenol is a natural compound used in cosmetics material. Alternative Names: 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate. Tea, ext. [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate. CAS No. 84650-60-2. Product ID: PIPE-0700. Molecular formula: C22H18O11. Mole weight: 458.4. EINECS: 283-519-7. SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O. Appearance: Powder. Category: Natural Extract.
Epinephrine Bitartrate/Adrenaline Acid Tartrate
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS. Alternative Names: l-Adrenaline bitartrate. Bronitin. Epinephrine acid tartrate. CAS No. 51-42-3. Product ID: API51423. Molecular formula: C13H19NO9. Mole weight: 333.29. EINECS: 200-097-1. SMILES: CNCC(C1=CC(=C(C=C1)O)O)O.C(C(C(=O)O)O)(C(=O)O)O. Category: APIs for Chronic Cardiac Insufficiency.
Epirubiein Hydrochloride
Epirubicin hydrochloride is an antitumor antibiotic which is epimeric with doxorubicin a t the 4-position of the amino sugar moiety. Alternative Names: 5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-alpha-l-arabino-hexopyranosy;8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-l)oxy)-hyd;EPIRUBICIN HYDROCHLORIDE EP STANDARD. CAS No. 56390-09-1. Product ID: API56390091. Molecular formula: C27H30ClNO11. Mole weight: 579.98. InChIKey: MWWSFMDVAYGXBV-UAOJCOQHSA-N. EINECS: 260-145-2. SMILES: C12=C(O)C3=C(C(=O)C4=C(C3=O)C=CC=C4OC)C(O)=C1[C@@]([H])(O[C@H]1O[C@@H](C)[C@H](O)[C@@H](N)C1)C[C@](O)(C(=O)CO)C2.Cl. Appearance: Powder. Standard: EP. Category: Anti-Tumor APIs.
Eplerenone
Eplerenone is an aldosterone antagonist with more specificity for the mineralocorticoid receptor (MCR) than spironolactone, having lower affinity for progesterone, androgen, and glucocorticoid receptors. CAS No. 107724-20-9. Product ID: API107724209. SMILES: C[C@]12CCC(=O)C=C1C[C@H]([C@@H]3[C@]24[C@H](O4)C[C@]5([C@H]3CC[C@@]56CCC(=O)O6)C)C(=O)OC. Category: Active Pharmaceutical Ingredients.
Epoprostenol Sodium
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY). Alternative Names: Prostacyclin sodium salt. Flolan. Cyclo-Prostin. CAS No. 61849-14-7. Product ID: API61849147. Molecular formula: C20H31NaO5. Mole weight: 374.4. EINECS: 263-273-7. SMILES: CCCCCC(C=CC1C(CC2C1CC(=CCCCC(=O)[O-])O2)O)O.[Na+]. Appearance: White powder. Category: Antihypertensive APIs.
Eprinomectin
Eprinomectin is a semi-synthetic GABA signaling potentiator used to inhibit bacterial infections. It causes neuromuscular paralysis in microbes and parasites. Eprinomectin is an avermectin selected for development as a topical endectocide. Alternative Names: Eprinex. Ivomec Eprinex. MK 397. MK-397. MK397. CAS No. 123997-26-2. Product ID: API123997262. Molecular formula: C50H75NO14. Mole weight: 914.13. Standard: USP. Category: Antibacterial APIs.
Eptifibatide
Eptifibatide is a Platelet Aggregation Inhibitor. The physiologic effect of eptifibatide is by means of Decreased Platelet Aggregation. Alternative Names: Integrelin. Integrilin. Intrifiban. CAS No. 188627-80-7. Product ID: API188627807. Molecular formula: C35H49N11O9S2. Mole weight: 832. EINECS: 641-366-7. SMILES: C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N. Category: Peptide APIs.
Erdafitinib
Erdafitinib is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively. CAS No. 1346242-81-6. Product ID: API1346242816. SMILES: CC(C)NCCN(C1=CC2=NC(=CN=C2C=C1)C3=CN(N=C3)C)C4=CC(=CC(=C4)OC)OC. Category: Active Pharmaceutical Ingredients.
Ergothioneine
Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine. Alternative Names: ERGOLD;2-MERCAPTOHISTIDINE BETAINE;(S)-ALPHA-CARBOXY-2,3-DIHYDRO-N,N,N-TRIMETHYL-2-THIOXO-1H-IMIDAZOLE-4-ETHANAMINIUM INNER SALT;THIONEINE;(S)-[1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl]trimethylammonium hydroxide;1H-Imidazole-4-ethanaminium. alpha.-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, inner salt, (.alpha.S)-;3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-trimethylammonio-propanoate. CAS No. 497-30-3. Product ID: CIA497303. Molecular formula: C9H15N3O2S. Mole weight: 229.3. EINECS: 207-843-5. SMILES: C[N+](C)(C)[C@@H](CC1=CNC(=S)N1)C(=O)[O-]. Appearance: White Solid. Category: Cosmetic Ingredients and Additives.
Eribulin
Eribulin mesylate is a methanesulfonate salt obtained by reaction of eribulin with one equivalent of methanesulfonic acid. A fully synthetic macrocyclic ketone analogue of marine sponge natural products. Inhibits growth phase of microtubules via tubulin-based antimitotic mechanism, which leads to G2/M cell-cycle block, disruption of mitotic spindles, and, ultimately, apoptotic cell death after prolonged mitotic blockage. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It contains an eribulin(1+). Alternative Names: Halaven. Eribulin mesilate. Eribulin (mesylate). CAS No. 441045-17-6. Product ID: API441045176. Molecular formula: C41H63NO14S. Mole weight: 826. EINECS: 813-106-4. SMILES: CC1CC2CCC3C(=C)CC(O3)CCC45CC6C(O4)C7C(O6)C(O5)C8C(O7)CCC(O8)CC(=O)CC9C(CC(C1=C)O2)OC(C9OC)CC(CN)O.CS(=O)(=O)O. Appearance: Powder. Category: Anti-Tumor APIs.
Ertugliflozin
Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Alternative Names: PF-04971729. Steglatro. PF04971729. CAS No. 1210344-57-2. Product ID: API1210344572. Molecular formula: C22H25ClO7. Mole weight: 436.9. EINECS: 810-048-1. SMILES: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@@]34[C@@H]([C@H]([C@@H]([C@@](O3)(CO4)CO)O)O)O)Cl. Appearance: White to Off-white Solid. Category: Hypoglycemic APIs.
Erythritol
Erythritol is a sweetener (polyol) manufactured by fermentation of glucose, the glucose-rich substrate being obtained by the enzymatic hydrolysis of starch. it is 60-70% as sweet as sugar, has excellent heat and acid stability, a high digestive tolerance, and a caloric value of 0.2 kcal/g. it is the only polyol produced by fermentation. it can be used as a sugar replacement in confectioneries, beverages, and desserts. Alternative Names: 1,2,3,4-Butanetetrol, (R*,S*)-;2,3,4-Butanetetrol,(R*,S*)-1;3,4-butanetetrol,(theta,s)-2;Antierythrite;Butanetetrol;Erythrit;Erythritol, meso-;erythritol,meso-. CAS No. 149-32-6. Product ID: PIPE-0065. Molecular formula: C4H10O4. Mole weight: 122.12. EINECS: 205-737-3. SMILES: C([C@H]([C@H](CO)O)O)O. Appearance: Crystalline Powder or Crystals. Category: Natural Extract.
Escin
Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility. Alternative Names: beta-Escin. Aescin. AESCINE. CAS No. 6805-41-0. Product ID: PIPE-0790. Molecular formula: C55H86O24. Mole weight: 1131.3. EINECS: 229-880-6. SMILES: C/C=C(\C)/C(=O)O[C@H]1[C@@H]([C@@]2([C@@H](C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C.C/C=C(/C)\C(=O)O[C@H]1[C@@H]([C@@]2([C@@H](C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C. Category: Natural Extract.
Escitalopram Oxalate
S-enantiomer of CITALOPRAM. Belongs to a class of drugs known as SELECTIVE SEROTONIN REUPTAKE INHIBITORS, used to treat depression and generalized anxiety disorder. Alternative Names: Lexapro. (S)-Citalopram Oxalate. Escitalopram (oxalate). CAS No. 219861-08-2. Product ID: API219861082. Molecular formula: C22H23FN2O5. Mole weight: 414.4. EINECS: 620-544-8. SMILES: CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.C(=O)(C(=O)O)O. Appearance: White Solid. Category: Antidepressant APIs.
Esculin
Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark[1]. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti - oxidative stress and anti - inflammatory effects, via the MAPK signaling pathway. CAS No. 531-75-9. Product ID: API531759. Mole weight: 340.29. SMILES: C1=CC(=O)OC2=CC(=C(C=C21)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O. Appearance: Powder. Category: Active Pharmaceutical Ingredients.
Esmolol hydrochloride
Esmolol Hydrochloride is the hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation. Alternative Names: Esmolol HCL. Brevibloc. Esmolol (hydrochloride). CAS No. 81161-17-3. Product ID: API81161173. Molecular formula: C16H26ClNO4. Mole weight: 331.8. EINECS: 636-017-0. SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O.Cl. Appearance: White or off-white crystalline powder. Category: Antiarrhythmic APIs.
Esomeprazole
Esomeprazole is a Proton Pump Inhibitor. The mechanism of action of esomeprazole is as a Proton Pump Inhibitor, and Cytochrome P450 2C19 Inhibitor. Alternative Names: (S)-Omeprazole. (S)-(-)-Omeprazole. (-)-Omeprazole. CAS No. 119141-88-7. Product ID: API119141887. Molecular formula: C17H19N3O3S. Mole weight: 345.4. EINECS: 643-098-6. SMILES: CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C(N2)C=C(C=C3)OC. Appearance: Solid. Standard: EP/BP/USP/IP. Category: Inhibit Gastric Acid Secretion APIs.
Esomeprazole magnesium trihydrate acts as a gastric proton pump inhibitor (PPI). In adults, esomeprazole is indicated for the treatment and maintenance of healing of erosive esophagitis, relieving of GERD symptoms; reduction of the risk for NSAID-associated gastric acid production. Alternative Names: Esomeprazole (Magnesium trihydrate). (s)-omeprazole magnesium trihydrate. MFCD31807353. CAS No. 217087-09-7. Product ID: API217087097. Molecular formula: C34H42MgN6O9S2. Mole weight: 767.2. EINECS: 669-839-3. SMILES: CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.O.O.O.[Mg+2]. Appearance: White or almost white powder. Category: Anti-Acid APIs.
Esomeprazole Potassium
Esomeprazole potassium is a proton pump inhibitor which acts as selective inhibiton of H+/K+-ATPase. With antiulcerative effects in vivo, it treats or ameliorates peptic ulcer or irritation of the gastrointestinal tract. Alternative Names: (s)-omeprazole potassium. Esomeprazole potassium salt. Potassium;5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide. CAS No. 161796-84-5. Product ID: API161796845. Molecular formula: C17H18KN3O3S. Mole weight: 383.5. EINECS: 695-792-3. SMILES: CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[K+]. Category: Anti-Acid APIs.
Esomeprazole Sodium
Esomeprazole Sodium is the sodium salt of the S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell. Alternative Names: Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide. (s)-omeprazole sodium salt. sodium;5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-3-ide. CAS No. 161796-78-7. Product ID: API161796787. Molecular formula: C17H18N3NaO3S. Mole weight: 367.4. EINECS: 620-470-6. SMILES: CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Na+]. Appearance: Pale Beige to Beige Solid. Category: Anti-Acid APIs.
Estradiol Benzoate
Estradiol Benzoate is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. Alternative Names: Oestradiol benzoate. Benovocylin. Estradiol 3-benzoate. CAS No. 50-50-0. Product ID: API50500. Molecular formula: C25H28O3. Mole weight: 376.5. EINECS: 200-043-7. SMILES: CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)C5=CC=CC=C5. Appearance: White crystalline powder. Category: Hormone and Endocrine Regulation APIs.
Estradiol enanthate
A derivative of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Alternative Names: Oestradiol 17-heptanoate. Estradiol Enantate. Estradiol 17-heptanoate. CAS No. 4956-37-0. Product ID: API4956370. Molecular formula: C25H36O3. Mole weight: 384.6. EINECS: 225-599-8. SMILES: CCCCCCC(=O)OC1CCC2C1(CCC3C2CCC4=C3C=CC(=C4)O)C. Appearance: White crystal or crystalline powder. Category: APIs for Estrogens.
Estradiol hemihydrate
Estradiol Hemihydrate is the hemihydrate form of estradiol, the most potent, naturally produced estrogen. Estradiol hemihydrate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. Alternative Names: beta-Estradiol semihydrate. UNII-CXY7B3Q98Z. CXY7B3Q98Z. CAS No. 35380-71-3. Product ID: API35380713. Molecular formula: C36H50O5. Mole weight: 562.8. EINECS: 631-198-2. SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O.O. Category: APIs for Estrogens.
Estradiol valerate
Estradiol Valerate is the parenterally-administered synthetic valerate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. Alternative Names: Estradiol 17-valerate. Estradiol valerianate. Delestrogen. CAS No. 979-32-8. Product ID: API979328. Molecular formula: C23H32O3. Mole weight: 356.5. EINECS: 213-559-2. SMILES: CCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C3C=CC(=C4)O)C. Appearance: White crystalline powder. Category: APIs for Estrogens.
Estriol
Estriol is an estradiol metabolite shown to protect against mammary carcinogenisis. CAS No. 50-27-1. Product ID: API50271. SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H]([C@@H]2O)O)CCC4=C3C=CC(=C4)O. Category: Active Pharmaceutical Ingredients.
Etamsylate
Benzenesulfonate derivative used as a systemic hemostatic. Alternative Names: Cyclonamine. Aglumin. CAS No. 2624-44-4. Product ID: API2624444. Molecular formula: C10H17NO5S. Mole weight: 263.31. EINECS: 220-090-7. SMILES: CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O. Appearance: White crystalline powder. Category: Hemostatic APIs.
Ethambutol hydrochloride is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB) of the lungs. Alternative Names: Ethambutol dihydrochloride. Ethambutol HCL. Ethambutol Hydrochloride. Dadibutol. CAS No. 1070-11-7. Product ID: API1070117. Molecular formula: C10H26Cl2N2O2. Mole weight: 277.23. EINECS: 213-970-7. SMILES: CCC(CO)NCCNC(CC)CO.Cl.Cl. Appearance: White to Off-white Solid. Category: Antibacterial APIs.
Ethinylestradiol
17alpha-ethynylestradiol is a 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration. It has a role as a xenoestrogen. It is a 17-hydroxy steroid, a terminal acetylenic compound and a 3-hydroxy steroid. It is functionally related to a 17beta-estradiol and an estradiol. Alternative Names: ethinyl estradiol. Ethynylestradiol. ETHINYLESTRADIOL. Ethynyl estradiol. CAS No. 57-63-6. Product ID: API57636. Molecular formula: C20H24O2. Mole weight: 296.4. EINECS: 200-342-2. SMILES: CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)O. Appearance: fine white to creamy white powder. Category: APIs for Estrogens.
Sacubitril. Alternative Names: Ethyl 2-(triphenylphosphoranylidene)propionate. Ethyl 2-(triphenylphosphoranylidene)propanoate. (Carbethoxyethylidene)triphenylphosphorane. (1-Ethoxycarbonylethylidene)triphenylphosphorane. CAS No. 5717-37-3. Product ID: CHE5717373. Molecular formula: C23H23O2P. Mole weight: 362.4. EINECS: 227-215-4. SMILES: CCOC(=O)C(=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C. Category: Fine Chemicals.
Ethyl Ascorbic Acid
3-O-Ethyl ascorbic acid ether, also called VC ethyl ether, is an ascorbic acid derivative. Alternative Names: 3-O-Ethyl Ascorbyl Ether;ETHYL ASCORBIC ACID;3-o-ethyl-l-ascorbic acid;3-O-ETHYLASCORBICACID;(5R,1'S)-5-(1,2-Dihydroxy-ethyl)-4-ethoxy-3-hydroxy-5H-furan-2-one;(5r)-5-[(1s)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-5h-furan-2-one;(R)-5-((S)-1,2-dihydroxyethyl)-4-ethoxy-3-hydroxyfuran-2(5H)-one. CAS No. 86404-04-8. Product ID: CIA86404048. Molecular formula: C8H12O6. Mole weight: 204.18. EINECS: 617-849-3. SMILES: CCOC1=C(C(=O)O[C@@H]1[C@H](CO)O)O. Appearance: Solid. Category: Cosmetic Ingredients and Additives.
Ethylene glycol
Ethylene glycol. Alternative Names: 2-Hydroxyethanol;Aliphatic diol;Athylenglykol;Dihydroxyethane;dowtherm;Dowtherm SR 1;dowthermsr1;ethane-1. CAS No. 107-21-1. Product ID: CHE107211. Molecular formula: C2H6O2. Mole weight: 62.07. EINECS: 203-473-3. SMILES: C(CO)O. Appearance: Viscous Liquid. Category: Other Chemicals.
Ethylene glycol diacetate
Used in the manufacture of perfumes, printing ink, lacquers and resins. Alternative Names: ETHYLENE GLYCOL DIACETATE. 1,2-Diacetoxyethane. Glycol diacetate. Ethylene diacetate. CAS No. 111-55-7. Product ID: CHE111557. Molecular formula: CH3COOCH2CH2OCOCH3. Mole weight: 146.14. EINECS: 203-881-1. SMILES: CC(=O)OCCOC(=O)C. Appearance: colorless liquid with a mild pleasant odor. Category: Acetates.
Ethylene glycol monoethyl ether acetate(CAC)
CAC is mainly used as solvents for the metal, furniture spray paint and smear paint. It can also be used as solvents of protective paint, dyestuff, resin, leather, printing ink; used in the cleanser formula of hard surface of metal, glass, etc.; and used as chemical reagent. Alternative Names: 2-Ethoxyethyl acetate. ETHYLENE GLYCOL MONOETHYL ETHER ACETATE. Cellosolve acetate. Oxitol acetate. CAS No. 111-15-9. Product ID: CHE111159. Mole weight: 132.16. EINECS: 203-839-2. SMILES: CCOCCOC(=O)C. Appearance: Colorless and clear liquid. Category: Chemicals.
Ethylhexyl Triazone
Ethylhexyl Triazone. Alternative Names: LOTSORB UVT-150;Ethyl Hexyl Triazone/Octyl Triazone;Ethylhexy Triazone;LGB-T150;Octyl lriazone;Uvinul T 150;2,4,6-Trianilino(p-carbo-2-ethylhexyloxy)-1,3,5-triazine. CAS No. 88122-99-0. Product ID: INT88122990. Mole weight: 823.07. EINECS: 402-070-1. Category: Intermediates.
Ethyl lactate is a metabolite found in or produced by Saccharomyces cerevisiae. Alternative Names: ethyl 2-methylprop-2-enoate. 2-Propenoic acid, 2-methyl-, ethyl ester. Ethyl 2-methylacrylate. CAS No. 97-63-2. Product ID: CHE97632. Molecular formula: C6H10O2. Mole weight: 114.144. EINECS: 202-597-5. SMILES: CCOC(=O)C(=C)C. Appearance: colorless liquid. Category: Acrylates.
Ethyl-pyrrolidone (NEP). Alternative Names: 1-Ethylpyrrolidin-2-one. 1-ETHYL-2-PYRROLIDINONE. 1-Ethyl-2-pyrrolidone. N-Ethyl-2-pyrrolidone. CAS No. 2687-91-4. Product ID: CHE2687914. Molecular formula: C6H11NO. Mole weight: 113.16. EINECS: 220-250-6. SMILES: CCN1CCCC1=O. Appearance: Clear colorless to light yellow liquid. Category: Other Chemicals.
Etodolie acid
The non-steroidal anti-inflammatory drugs of Indole acetic acid class has the analgesic and anti-inflammatory effect. Alternative Names: (R)-2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid;22α-Hydroxyerythrodiol Solution, 100ppm;Etodolac Imp.(EP);Etodolac impurity;1,8-DIETHYL-1,3,4,9-TETRAHYDRO-PYRANO[3,4-B]INDOLE-1-ACETIC ACID. CAS No. 41340-25-4. Product ID: API41340254. Molecular formula: C17H21NO3. Mole weight: 287.35. InChIKey: NNYBQONXHNTVIJ-QGZVFWFLSA-N. EINECS: 629-689-1. Category: Nonsteroidal Anti-inflammatory (NSAID) APIs.
Etonogestrel
Etonogestrel is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin and a female contraceptive drug. Alternative Names: Implanon. 3-Oxodesogestrel. 3-Ketodesogestrel. CAS No. 54048-10-1. Product ID: API54048101. Molecular formula: C22H28O2. Mole weight: 324.5. EINECS: 258-936-2. SMILES: CC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34. Appearance: White to Off-White Solid. Category: APIs for Progestogens.
Etoricoxib
Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Alternative Names: Arcoxia. Tauxib. Nucoxia. CAS No. 202409-33-4. Product ID: API202409334. Molecular formula: C18H15ClN2O2S. Mole weight: 358.8. EINECS: 682-421-5. SMILES: CC1=NC=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C. Appearance: Off-White Solid. Category: Nonsteroidal Anti-inflammatory (NSAID) APIs.