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Ampicillin Beta-Lactamase Modified, 1000X
Ampicillin Beta-Lactamase Modified, is a unique antibiotic that is a stronger inhibitor of b-Lactamase than ampicillin, carbenicillin or methicillin. Ampicillin is modified utilizing a novel method that results in improved transformation efficiencies where higher cell density and longer incubation times traditionally result in the development of ampicillin sensitive satellite colonies. When used at a concentration of 1X, the presence of satellite colonies Identificatis reduced, even after prolonged incubation (2-4 days) and plating of competent cells at 20 fold higher density. Group: Biochemicals. Grades: Molecular Biology Grade. Pack Sizes: 3x1ml. US Biological Life Sciences.
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Ampicillin Sodium Salt
Ampicillin Sodium Salt is a readily-soluble form of ampicillin. It belongs to the group of beta-lactam antibiotics. These antibotics gram-negative bacteria to which E. coli and Salmonella belong. beta-lactam antibiotic prevent the formation of peptidoglycan, an essential building block of the cell membrane. Thus, preventing growth of cells. Used to select for drug-resistant, plasmid-bearing bacteria. Group: Biochemicals. Alternative Names: 6-[D-(-)-alpha-Aminophenylacetamido]-penicillanic acid, sodium salt; Sodium [2S-[2α,5α,6 β (S*)]]-6-(aminophenylacetamido)-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylate. Grades: Molecular Biology Grade. CAS No. 69-52-3. Pack Sizes: 5g, 25g, 100g, 250g, 500g. Molecular Formula: C16H18N3O4SNa, Molecular Weight: 371.4. US Biological Life Sciences.
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Ampicillin Solution 50mg/ml
Ampicillin Solution, 50mg/ml, is a convenient, ready to use concentrated solution for molecular biology selection applications. It belongs to the group of beta-lactam antibiotics. These antibotics gram-negative bacteria to which E. coli and Salmonella belong. Beta-lactam antibiotic prevent the formation of peptidoglycan, an essential building block of the cell membrane. Thus, preventing growth of cells. Group: Biochemicals. Alternative Names: 6-[D-(-)-alpha-Aminophenylacetamido]-penicillanic acid, sodium salt; Sodium [2S-[2α,5α,6 β (S*)]]-6-(aminophenylacetamido)-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylate. Grades: Molecular Biology Grade. CAS No. 69-52-3. Pack Sizes: 20ml, 5x20ml. US Biological Life Sciences.
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Ampicillin Thiazepine Analog (EP Impurity N)
Ampicillin Thiazepine Analog (EP Impurity N) is an analog and impurity of Ampicillin (A634300) and is also a useful intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H19N3O4S; (HCl), Molecular Weight: 349.4. US Biological Life Sciences.
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Amprenavir (141W94, KVX-478, Agenerase, Prozei,)
Amprenavir (141W94, KVX-478, Agenerase, Prozei,). Group: Biochemicals. Alternative Names: 141W94, KVX-478, Agenerase, Prozei. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Amprenavir-d4
Labeled Amprenavir, a selective HIV protease inhibitor. An analogue of Ritonavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Anabaseine (3,4,5,6-Tetrahydro-2,3-bipyridine)
A naturally occurring neurotoxin produced by hoplonemertine sea worms competes with the natural neurotransmitter acetylcholine when binding to nicotinic receptor sites. Group: Biochemicals. Alternative Names: 3,4,5,6-Tetrahydro-2,3-bipyridine. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Cell-permeable. A potent, non-competitive inhibitor of p300 and PCAF (p300/CBP-associated factor) histone acetyltransferase (HAT) activities (IC50~8.5uM and ~5uM, respectively. Inhibits SUMOylation of RanGAP1-C2 with an IC50=2.2uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 16611-84-0. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
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Anagrelide-13C3
Labeled Anagrelide, which is used as an antithrombocythemic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Used as an antithrombocythemic. Group: Biochemicals. Alternative Names: BL-4162A, BMY-26538-01, Agrylin. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Labelled Anastrozole, an aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Anastrozole (ZD-1033, ICI-D-1033, Arimidex)
An aromatase inhibitor. Used as an antineoplastic. Group: Biochemicals. Alternative Names: ZD-1033, ICI-D-1033, Arimidex. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Anatoxin-a (NRC Certified Calibration Solution). Concentration: 30 μmol/L of ATX in Methanol/Water (9:91 v/v) with 0.01% Acetic Acid
Anatoxin-a is a cyanobacterial toxin linked to animal deaths in North America and globally. Group: Biochemicals. Grades: Highly Purified. CAS No. 64285-06-9. Pack Sizes: 500ul. Molecular Formula: C10H15NO, Molecular Weight: 165.23. US Biological Life Sciences.
An aromatase inhibitor. Group: Biochemicals. Alternative Names: 4-Androsten-3, 6, 17-trione. Grades: Purified. CAS No. 2243-6-3. Pack Sizes: 25mg. US Biological Life Sciences.
Nomenclature: 1,4,6--Androstatriene-3,17-Dione. Group: Biochemicals. Alternative Names: 1, 4, 6-Androstariene-3, 17-dione. Grades: Purified. CAS No. 633-35-2. Pack Sizes: 500mg. US Biological Life Sciences.
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Anguinomycin A (5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A)
Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumour activity in mice against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of Leptomycin B, an inhibitor of nuclear export of proteins. Group: Biochemicals. Alternative Names: 5-Demethyl-leptomycin A, KR 2827A, Antibiotic KR 2827A. Grades: Highly Purified. CAS No. 111278-01-4. Pack Sizes: 100ug. US Biological Life Sciences.
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Anisaldehyde-[7-13C]
Anisaldehyde-[7-13C]. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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Anisole-d8
Anisole-d8 is the labeled analogue of Anisole (A673900), which is used in perfumery. Group: Biochemicals. Grades: Highly Purified. CAS No. 54887-54-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C7D8O, Molecular Weight: 116.19. US Biological Life Sciences.
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Anisomycin (Flagecidin, Antibiotic SA 3097C1, Antibiotic PA 106, Anhydroscopin A, NSC)
Anisomycin is a phenyl methyl enepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin acts as an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal models. More recently, anisomycin has been demonstrated to induce apoptosis, to be a selective signalling agonist, to activate mitogen-activated protein (MAP) kinases and to be immunomodulatory via its action on T cells. Group: Biochemicals. Alternative Names: ((2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate. Grades: Highly Purified. CAS No. 22862-76-6. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences.
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ANKTM1
ANKTM1 is a cold-activated channel found in sensory neurons. It is a member of the TRP family of temperature activated receptors. It has been shown to be localized in a sub-set of sensory neurons, where it is co-expressed with TRPV1 (Capsacian receptor), but not TRPM8, a TRPM cold-sensing channel. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1ml. US Biological Life Sciences.
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ANKTM1 (KLH)
ANKTM1 is a cold-activated channel found in sensory neurons. It is a member of the TRP family of temperature activated receptors. It has been shown to be localized in a sub-set of sensory neurons, where it is co-expressed with TRPV1 (Capsacian receptor), but not TRPM8, a TRPM cold-sensing channel. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1ml. US Biological Life Sciences.
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Annexin II, Positive Control, Bovine Lung, Binding Membrane Fraction
Annexin II, Positive Control, Bovine Lung, Binding Membrane Fraction. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1Vial. US Biological Life Sciences.
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Annexin II, Positive Control, Bovine Lung, Supernatant
Annexin II, Positive Control, Bovine Lung, Supernatant. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1Vial. US Biological Life Sciences.
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Annexin VI, p70, Control Fraction, Crude Membrane-binding Annexin Fragment
Control Fraction for A2296-61. Group: Molecular Biology. Pack Sizes: 1vial. US Biological Life Sciences.
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Ansatrienin A (Mycotrienin I, Antibiotic T 23I, T 23I)
Ansatrienin A, isolated from a Streptomyces sp., is closely related to the Cytotrienins. It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption. Ansatrienin A also significantly potentiates the action of several clinical anti-cancer agents. Group: Biochemicals. Alternative Names: Mycotrienin I, Antibiotic T 23I, T 23I. Grades: Highly Purified. CAS No. 82189-03-5. Pack Sizes: 1mg. US Biological Life Sciences.
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Ansatrienin B (Antibiotic T 23II, Mycotrienin II, T 23II)
Also know as Mycotrienin II and Antibiotic T 23II, Ansatrienin B isolated from a Streptomyces sp. is closely related to the Cytotrienins. It displays potent anticancer activity against cell lines and inhibits osteoclastic bone resorption. Ansatrienin B also significantly potentiates the action of several clinical anti-cancer agents. Group: Biochemicals. Alternative Names: Antibiotic T 23II, Mycotrienin II, T 23II. Grades: Highly Purified. CAS No. 82189-04-6. Pack Sizes: 1mg. US Biological Life Sciences.
Antibiotic A23187 is a calcium ionophore. It causes rapid influx of calcium in various cells across biological membranes. Calcimycin was isolated from Streptomyces chartreusis in 1974. Calcimycin is a spiroketal substituted by pyrollic and benzoxazolyl groups which afford its high affinity and selectivity for calcium. Calimycin exhibits broad biological activity against bacteria, fungi and protozoa. It has found wide application as a research tool for calcium regulated cellular events. Group: Biochemicals. Alternative Names: Calcimycin, Calcium Ionophore A23187. Grades: Molecular Biology Grade. CAS No. 52665-69-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C29H37N3O6, Molecular Weight: 523.6. US Biological Life Sciences.
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Antibiotic K252A (Antibiotic SF 2370)
Antibiotic K252A is a staurosporine analogue isolated from a Nocardiopsis strain as a potent inhibitor of protein kinase C. Antibiotic K252A exhibits potent antitumor activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents. More extensive investigation has demonstrated that while antibiotic K252A is a potent inhibitor of Ca2+/calmodulin kinase II, it is also active against other kinases, notably myosin light chain kinase, cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and cGMP-dependent protein kinase (PKG). Group: Biochemicals. Grades: Highly Purified. CAS No. 99570-78-2. Pack Sizes: 500ug. US Biological Life Sciences.
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Antibiotic L-681,217 (L 681217)
Antibiotic L 681,217 is a glycolipid-type antibiotic related to the efrotomycin class isolated from a Streptomyces sp. It inhibits bacterial protein synthesis at the elongation stage, its target being elongation factor Tu (EF-Tu). Antibiotic L 681,217 also shows broad spectrum antibiotic activity against gram-positive and gram-negative bacteria. Group: Biochemicals. Alternative Names: L 681217. Grades: Highly Purified. CAS No. 93522-10-2. Pack Sizes: 500ug. US Biological Life Sciences.
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Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010)
Antibiotic RK-682 is the calcium salt of one of a complex family of tetronic acids isolated from Streptomyces species. The formation of the salt is almost certainly an artefact of silica chromatography. RK-682 is the most extensively studied of the analogues, having been shown to inhibit protein tyrosine phosphatases and heparanase. Pharmacological studies with RK-682 demonstrated enhanced ATP-induced long-term potentiation using guinea-pig hippocampal slices. Investigation of the complex has also shown potent activity against HIV-1 protease. Group: Biochemicals. Alternative Names: Antibiotic TAN 1364B, Antibiotic CI 010. Grades: Highly Purified. CAS No. 154639-24-4(TAN1364B). Pack Sizes: 500ug. US Biological Life Sciences.
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Antibiotic TPU-0037-A (30-Demethyl-lydicamycin)
TPU-0037A, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037A is also closely related to Antibiotic BN 4515N isolated from a strain of Microtetraspora as a neuritogenic agent. Group: Biochemicals. Alternative Names: 30-Demethyl-lydicamycin. Grades: Highly Purified. CAS No. 485815-59-6. Pack Sizes: 500ug. US Biological Life Sciences.
TPU-0037C, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037C is also closely related to Antibiotic BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent. Group: Biochemicals. Alternative Names: 8-Dehydroxy-30-demethyl-lydicamycin. Grades: Highly Purified. CAS No. 485815-61-0. Pack Sizes: 500ug. US Biological Life Sciences.
Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and cyclin-dependent kinase 2 (CDK2) resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these anti-cancer agents. Group: Biochemicals. Alternative Names: 7-Hydroxystaurosporine, UCN-01. Grades: Highly Purified. CAS No. 112953-11-4. Pack Sizes: 1mg. US Biological Life Sciences.
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Antibiotic UCN-02 (UCN 02)
UCN-02 is isolated as a minor co-metabolite of high producing staurosporine strains of selected actinomycetes. Although less selective than its isomer UCN-01, UCN-02 exhibits comparable activity and probably acts by similar mechanisms. Group: Biochemicals. Alternative Names: UCN 02. Grades: Highly Purified. CAS No. 121569-61-7. Pack Sizes: 1mg. US Biological Life Sciences.
Analgesic. Group: Biochemicals. Alternative Names: 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; 2-Trideuteromethyl-3-methyl-1-phenyl-3-pyrazolin-5-one; Analgesine; Anodynine; Sedatine. Grades: Highly Purified. CAS No. 60-80-0. Pack Sizes: 1g. US Biological Life Sciences.
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a,O-Dimethyl tyrosine
a,O-Dimethyl tyrosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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Aorta, Bovine
Aorta, Bovine. Group: Biologicals. Grades: Tissue. Pack Sizes: 10Ea. US Biological Life Sciences.
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Aorta, Rabbit
Aorta, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences.
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Apicidin
Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis. A potent, cell permeable inhibitor of histone deacetylase (IC50 = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC50 = 50 - 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin. Group: Biochemicals. Alternative Names: Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]; Cyclo(8-oxo-L-2-aminodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-D-2-piperidinecarbonyl); Apicidin Ia; OSI 2040. Grades: Highly Purified. CAS No. 183506-66-3. Pack Sizes: 2mg. US Biological Life Sciences.
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Apigenin (4',5,7-Trihydroxyflavone)
Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignan. Group: Biochemicals. Alternative Names: 4',5,7-Trihydroxyflavone. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Apigenin 7- β-D-Gucopyranoside Triacetate Methyl Ester is an intermediate in synthesizing Isorhoifolin (I819700), a naturally occurring flavonoid that was shown to exhibit potential antidiabetic, antihyperlipidemic and antioxidant effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C28H28O14, Molecular Weight: 588.51. US Biological Life Sciences.
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Apoptolidin
Apoptolidin, originally isolated from a Nocardiopsis sp., induces apoptotic cell death in rat glial cells transformed with the adenovirus E1A oncogene at an IC50 = 11 ng/ml. It is among the most selective cytotoxic agents tested by the NCI in human cancer cell lines. Although the apoptotic activity of apoptolidin correlates with F0F1-ATPase inhibition, recent evidence suggests the existence of a secondary biological target or more complex mode of action. Group: Biochemicals. Grades: Highly Purified. CAS No. 194874-06-1. Pack Sizes: 100ug. US Biological Life Sciences.
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Aposcopolamine
A urinary metabolite of Scopolamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 535-26-2. Pack Sizes: 10mg. US Biological Life Sciences.
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Aposcopolamine, Hydrochloride Salt
A urinary metabolite of Scopolamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Aprepitant is a structurally n. Group: Biochemicals. Alternative Names: 5-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-1, 2-dihydro-3H-1, 2, 4-triazol-3-one, Emend. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Aquaporin 3, Control Peptide (AQP3, GLIP, Glycerol-transporting Integral Protein)
Control Antigen for A3000-10. Group: Molecular Biology. Grades: Purified. Pack Sizes: 40ug. US Biological Life Sciences.
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Arachidic Acid Methyl Ester-d3
Arachidic Acid Methyl Ester-d3 is an isotope analog of Arachidic Acid Methyl Ester. Arachidic Acid Methyl Ester is used in biological studies to evaluate the antioxidant activity and chemical compounds of Capsicum annuum acuminatum during fruit ripening. This is the methyl analog of arachidic acid, which is used for the production of detergents, photographic materials and lubricants. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C21H39D3O2, Molecular Weight: 329.58. US Biological Life Sciences.
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AR-C155858
AR-C155858. Group: Biochemicals. Alternative Names: (S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; 2-[[6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxothieno[2,3-d]pyrimidin-5-yl]carbonyl]-4-isoxazolidinol;(S)-6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[(4-hydroxyisoxazolidin-2-yl)carbonyl]-1-isobutyl-3-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AR-C 155858. Grades: Highly Purified. CAS No. 496791-37-8. Pack Sizes: 1mg. US Biological Life Sciences.
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Arecoline-d5, Hydrobromide Salt (1,2,5,6-Tetrahydro-1-(methyl-d3)-3-pyridine-2,6-d2-carboxylic Acid, Methyl Ester Hydrobromide)
Labelled Arecoline, which is reported to be a cholinergic agonist that readily crosses the blood-brain barrier. Group: Biochemicals. Alternative Names: 1,2,5,6-Tetrahydro-1-(methyl-d3)-3-pyridine-2,6-d2-carboxylic Acid, Methyl Ester Hydrobromide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Aristolochic acids occur in Aristolochiaceae and in butterflies feeding on these plants. Group: Biochemicals. Alternative Names: 8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic Acid; Aristolochine. Grades: Highly Purified. CAS No. 313-67-7. Pack Sizes: 25mg. US Biological Life Sciences.
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Arsenic Oxide (As2O3)
Arsenic Oxide ((As2O3)) is used as a precursor to forestry products, in colorless glass production, and in electronics. In combination with copper(II), acetate arsenic trioxide gives Copper Acetoarsenite (C685255) as a rodenticide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1327-53-3. Pack Sizes: 10g, 25g. Molecular Formula: As2O3, Molecular Weight: 197.84. US Biological Life Sciences.
Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinhao. Group: Biochemicals. Alternative Names: Artemisine, Arteannuin, Huanghuahaosu, QHS. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
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Ascochlorin (Antibiotic LL-Z 1272 gamma)
The antitumour fungal metabolite ascochlorin specifically inhibits matrix metalloproteinase-9 (MMP9) activity through suppression of activator protein-1 (AP-1) dependent induction of MMP-9 gene expression. Via AP-1 suppression ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses. Group: Biochemicals. Alternative Names: Antibiotic LL-Z 1272 gamma. Grades: Highly Purified. CAS No. 26166-39-2. Pack Sizes: 500ug. US Biological Life Sciences.
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Ascomycin
Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells.Ascomycin (also known as Immunomycin, FR 900520, and FK-520) is an analog of tacrolimus (FK-506) with immunosuppressive, neurotrophic and antifungal activities. Ascomycin can be used to prevent rejection after an organ transplant, and to treat autoimmune diseases and skin diseases.Ascomycin inhibits the production of T helper type 1 (Th1) (interferon and IL-2) and Th2 (IL-4 and IL-10) cytokines in target cells. Paul, C., et al. "Ascomycins: promising agents for the treatment of inflammatory skin diseases." Expert Opin. Investig. Drugs. 9: 69-77 (2000). Moll...the compounds." J. Infect. Dis. 191: 1342-1349 (2005).FK-520 might be a substrate for P-glycoprotein; expression of P-glycoprotein in yeast cells resulted in resistance to growth inhibition by FK-520. Raymond, M., et al. "Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520." Mol. Cell Biol. 14: 277-286 (1994). Group: Biochemicals. Alternative Names: Immunomycin; FK-520; FR-520; NSC-106410; FR 900520; L 683590; Changchuanmycin. Grades: Highly Purified. CAS No. 104987-12-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C43H69NO12, Molecular Weight: 792.01. US Biological Life Sciences.
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Ascorbic Acid USP (L-Ascorbic acid, Vitamin C)
Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs. Group: Biochemicals. Alternative Names: (+)-Ascorbic Acid; 100M; L-threo-Ascorbic Acid. Grades: Cell Culture Grade. CAS No. 50-81-7. Pack Sizes: 100g, 250g, 500g, 1Kg, 2.5Kg, 5Kg. US Biological Life Sciences.
Cholinesterase reactivator. A potential antidote for organophosphate poisoning. Group: Biochemicals. Alternative Names: 1 [ [ [4- (Aminocarbonyl) pyridinio] methoxy] methyl] -2- [ (hydroxyimino) methyl] pyridinium Dichloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Aspercolorin
Aspercolorin is an atypical cyclic tetrapeptide in which one of the amino acids is an 5-methoxyanthranilic acid. Recently, aspercolorin has found application as a secondary metabolite standard for polyphasic taxonomy for the identication of Aspergillus versicolor. No reports of any investigation of the pharmacology of aspercolorin are available in the literature. Group: Biochemicals. Grades: Highly Purified. CAS No. 29123-52-2. Pack Sizes: 1mg. US Biological Life Sciences.
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Assay Buffer (10X)
Assay Buffer (10X). Group: Molecular Biology. Alternative Names: For Human Topoisomerase I, Cat#T8065A. US Biological Life Sciences.
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Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)
A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells. Group: Biochemicals. Alternative Names: Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A. Grades: Highly Purified. CAS No. 577-64-0. Pack Sizes: 1mg. US Biological Life Sciences.