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Our biochemicals, antibodies, recombinant proteins, cell culture media and molecular biology kits are used in virtually all scientific applications.From affordable research quantities to larger bulk amounts.
Product | Description | |
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(R)-Hydroxy Iloperidone Quick inquiry Where to buy | (R)-Hydroxy Iloperidone. Group: Biochemicals. Alternative Names: (αR)-4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy-α-methyl-benzenemethanol. Grades: Highly Purified. CAS No. 501373-87-1. Pack Sizes: 10mg. Molecular Formula: C24H29FN2O4, Molecular Weight: 428.5. US Biological Life Sciences. | Worldwide |
(R)-Hydroxy Iloperidone-d3 Quick inquiry Where to buy | (R)-Hydroxy Iloperidone-d3. Group: Biochemicals. Alternative Names: (αR)-4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxy-α-methyl-benzenemethanol-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C24H26D3FN2O4, Molecular Weight: 431.51. US Biological Life Sciences. | Worldwide |
Ribitol-1,2,3,4,5-13C5 Quick inquiry Where to buy | Ribitol-1,2,3,4,5-13C5. Group: Biochemicals. Alternative Names: Adonitol-1,2,3,4,5-13C5. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: 13C5H12O5, Molecular Weight: 157.11. US Biological Life Sciences. | Worldwide |
Ridane N-Carboxylic Acid tert-Butyl Ester Quick inquiry Where to buy | Protected Ridane (R495950), a piperidylpropanone derivative with anti-coccidiosis effect. Group: Biochemicals. Alternative Names: trans-1-(3-Methoxy-1-N-tert-butyloxycarbonyl-2-piperidinyl)-2-propanone. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
Rifabutin Impurity C Quick inquiry Where to buy | Rifabutin Impurity C is an impurity of Rifabutin (R505000), a semisynthetic derivative of Rifamycin S that inhibits nucleic acid synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1242076-45-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C46H60N4O11, Molecular Weight: 844.99. US Biological Life Sciences. | Worldwide |
Rimeporide-15N3 Hydrochloride Quick inquiry Where to buy | Rimeporide-15N3 Hydrochloride. Group: Biochemicals. Alternative Names: N- (Aminoiminomethyl) -2-methyl-4, 5-bis (methylsulfonyl) benzamide-15N3 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C11H16Cl15N3O5S2, Molecular Weight: 372.83. US Biological Life Sciences. | Worldwide |
Rimeporide Hydrochloride Quick inquiry Where to buy | Rimeporide Hydrochloride. Group: Biochemicals. Alternative Names: N- (Aminoiminomethyl) -2-methyl-4, 5-bis (methylsulfonyl) benzamide Hydrochloride. Grades: Highly Purified. CAS No. 187870-95-7. Pack Sizes: 10mg. Molecular Formula: C11H16ClN3O5S2, Molecular Weight: 369.84. US Biological Life Sciences. | Worldwide |
Riociguat Quick inquiry Where to buy | Riocguat is used in the treatment for pulmonary hypertension. Group: Biochemicals. Alternative Names: N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methylcarbamic Acid Methyl Ester; [4, 6-Diamino-2- [1- [ (2-fluorophenyl) methyl] -1H-pyrazolo [3, 4-b] pyridin-3-yl] -5-pyrimidinyl] methylcarbamic Acid Methyl Ester; BAY 63-2521; BAY 632521; Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate. Grades: Highly Purified. CAS No. 625115-55-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
(R)-Isoflurane Quick inquiry Where to buy | (R)-Isoflurane. Group: Biochemicals. Alternative Names: (2R)-2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane; (-)-Isoflurane; R-(-)-Isoflurane. Grades: Highly Purified. CAS No. 133098-04-1. Pack Sizes: 1mg. Molecular Formula: C3H2ClF5O, Molecular Weight: 184.49. US Biological Life Sciences. | Worldwide |
Risperidone 9-Ethylidenecarboxylate Quick inquiry Where to buy | Risperidone 9-Ethylidenecarboxylate. Group: Biochemicals. Alternative Names: (E)-2-(3-(2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-7,8-dihydro-4H-pyrido[1,2-a]pyrimidin-9(6H)-ylidene)acetic Acid. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H27FN4O4, Molecular Weight: 466.5. US Biological Life Sciences. | Worldwide |
Ritonavir Impurity (2S, 3S, 5S) -5-Amino-1, 6-diphenyl-2- ([[thiazol-5-ylmethoxy) carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Quick inquiry Where to buy | Ritonavir Impurity (2S, 3S, 5S) -5-Amino-1, 6-diphenyl-2- ([[thiazol-5-ylmethoxy) carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate. Group: Biochemicals. Alternative Names: Ritonavir Impurity. Grades: Highly Purified. CAS No. 959315-21-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?O?S? xHCl, Molecular Weight: 720.94. US Biological Life Sciences. | Worldwide |
Rizatriptan 1,2-(4-dimethylamino)butane Quick inquiry Where to buy | Rizatriptan 1,2-(4-dimethylamino)butane. Group: Biochemicals. Alternative Names: 3-[2-(Dimethylamino)ethyl]-δ-[3-[2-(dimethylamino)ethyl]-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-2-yl]-N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-1-butanamine. Grades: Highly Purified. CAS No. 1135479-41-2. Pack Sizes: 10mg. Molecular Formula: C36H49N11, Molecular Weight: 635.85. US Biological Life Sciences. | Worldwide |
Rizatriptan N,N,N-Trimethylethanammonium Chloride Quick inquiry Where to buy | Rizatriptan N,N,N-Trimethylethanammonium Chloride. Group: Biochemicals. Alternative Names: N,N,N-Trimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanaminium. Grades: Highly Purified. CAS No. 1030849-63-8. Pack Sizes: 10mg. Molecular Formula: C16H22ClN5, Molecular Weight: 319.83. US Biological Life Sciences. | Worldwide |
(R)-Ketamine-d6 L-Tartaric Acid Quick inquiry Where to buy | (R)-Ketamine-d6 L-Tartaric Acid is an intermediate in synthesizing (S)-Ketamine-d6 Hydrochloride (K165312), a labelled (S)-Ketamine (K165310, HCl salt) which is the more active enantiomer of the NMDA receptor antagonist and anesthetic agent Ketamine (K165300). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H10D6ClNO C4H6O6. US Biological Life Sciences. | Worldwide |
(R)-Levetiracetam Quick inquiry Where to buy | (R)-Levetiracetam. Group: Biochemicals. Alternative Names: (αR)-α-Ethyl-2-oxo-1-pyrrolidineacetamide; (R)-α-ethyl-2-oxo-1-pyrrolidineacetamide; (2R)-2-(2-Oxo-pyrrolidin-1-yl)butanamide; UCB-L 060. Grades: Highly Purified. CAS No. 103765-01-1. Pack Sizes: 2.5mg. Molecular Formula: C8H14N2O2, Molecular Weight: 170.21. US Biological Life Sciences. | Worldwide |
(R)-(-)-Littorine Hydrochloride Quick inquiry Where to buy | (R)-(-)-Littorine is a tropane alkaloid found in a variety of plants and have been found to potentially detoxify cells in overproducing conditions. Group: Biochemicals. Alternative Names: Littorine Hydrochloride; R(-)-3α-(2-Hydroxy-3-phenylpropionyloxy)-tropane Hydrochloride; [3 (R) -endo] - α -Hydroxy Benzene propanoic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl Ester Hydrochloride; 1αH,5αH-Tropan-3α-ol, 3-phenyl-L-lactate (ester) Hydrochloride; ( α R) - α -Hydroxy Benzene propanoic Acid (3-Endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl Ester Hydrochloride. Grades: Highly Purified. CAS No. free base: 21956-47-8. Pack Sizes: 100mg. Molecular Formula: C17H24ClNO3, Molecular Weight: 325.83. US Biological Life Sciences. | Worldwide |
R-Mevalonic Acid, Lithium Salt Quick inquiry Where to buy | Mevalonic acid is an intermediate in the mevalonate pathway, producing terpenes and steroids. This function provides treatment options metabolic disorders, R-mevalonate accumulates in patients with the autosomal recessively inherited mevalonic acidurias, an inborn error of cholesterol and nonsterol isoprene biosynthesis. Group: Biochemicals. Alternative Names: Lithium (R)-3,5-dihydroxy-3-methylpentanoate, Lithium (R)-3,5-dihydroxy-3-methylvalerate, R-MVA-Li. Grades: Highly Purified. CAS No. 1255502-07-8. Pack Sizes: 10mg. Molecular Formula: C6H11LiO4, Molecular Weight: 154.09. US Biological Life Sciences. | Worldwide |
(R)-Mevalonolactone Quick inquiry Where to buy | (R)-Mevalonolactone. Group: Biochemicals. Alternative Names: (-)-Mevalonolactone; (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one; (-)-(R)-Mevalonic Acid Lactone; (-)-(R)-Mevalonolactone. Grades: Highly Purified. CAS No. 19115-49-2. Pack Sizes: 25mg. Molecular Formula: C6H10O3, Molecular Weight: 130.139999999999. US Biological Life Sciences. | Worldwide |
(R)-N-[2-(2,6-dimethylphenoxy)-1-methylethyl]acetamide Quick inquiry Where to buy | (R)-N-[2-(2,6-dimethylphenoxy)-1-methylethyl]acetamide. Group: Biochemicals. Alternative Names: N-[(1R)-2-(2,6-dimethylphenoxy)-1-methylethyl]acetamide. Grades: Highly Purified. CAS No. 141552-89-8. Pack Sizes: 100mg. Molecular Formula: C13H19NO2, Molecular Weight: 221.3. US Biological Life Sciences. | Worldwide |
(R)-N-[(5-Cyano-2-aminophenyl)methyl]-N-[1-(hydroxymethyl)-2-phenylethyl]thiophene-2-sulfonamide Quick inquiry Where to buy | (R)-N-[(5-Cyano-2-aminophenyl)methyl]-N-[1-(hydroxymethyl)-2-phenylethyl]thiophene-2-sulfonamide is a reactant used in the preparation of 3,7-disubstituted-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine compounds, having farnesyl protein transferase inhibitory activity. Group: Biochemicals. Alternative Names: N-[(5-Cyano-2-aminophenyl)methyl]-N-[(1R)-1-(hydroxymethyl)-2-phenylethyl]-2-thiophenesulfonamide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
(R)-N-[(5-Cyano-2-nitrophenyl)methyl]-N-[1-(hydroxymethyl)-2-phenylethyl]thiophene-2-sulfonamide Quick inquiry Where to buy | (R)-N-[(5-Cyano-2-nitrophenyl)methyl]-N-[1-(hydroxymethyl)-2-phenylethyl]thiophene-2-sulfonamide is a reactant used in the preparation of 3,7-disubstituted-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine compounds, having farnesyl protein transferase inhibitory activity. Group: Biochemicals. Alternative Names: N-[(5-Cyano-2-nitrophenyl)methyl]-N-[(1R)-1-(hydroxymethyl)-2-phenylethyl]-2-thiophenesulfonamide. Grades: Highly Purified. CAS No. 530145-62-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
R)-(+)-N-Benzyl-1-phenylethylamine Quick inquiry Where to buy | R)-(+)-N-Benzyl-1-phenylethylamine. Group: Biochemicals. Alternative Names: (α R) -α -Methyl-N- (phenylmethyl) benzenemethanamine; (+)-Benzylphenethylamine; (+)-N-Benzyl-1-phenylethylamine; (+)-N-Benzyl-α-phenylethylamine; (R)-(+)-N-Benzyl-α-methylbenzylamine; (R)-Benzyl(α-methylbenzyl)amine; (R)-N-(α-Methylbenzyl)-N-benzylamine; (R)-N-Benzyl-1-phenyl-1-ethylamine; (R)-N-Benzyl-1-phenylethanamine; (R)-N-Benzyl-1-phenylethylamine; (R)-N-Benzyl-N-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; Benzyl((R)-1-phenylethyl)amine; N-Benzyl((R)-1-phenylethyl)amine; N-Benzyl-(R)-α-methylbenzylamine; N- [ (R) -1-Phenylethyl] benzylamine. Grades: Highly Purified. CAS No. 38235-77-7. Pack Sizes: 1g. Molecular Formula: C15H17N, Molecular Weight: 211.3. US Biological Life Sciences. | Worldwide |
(R)-N-Boc-pyrrolidine-3-methanol Quick inquiry Where to buy | (R)-N-Boc-pyrrolidine-3-methanol. Group: Biochemicals. Alternative Names: (3R)-3-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid 1,1-dimethylethyl Ester; (3R) -3- (Hydroxymethyl) pyrrolidine-1-carboxylic Acid tert-Butyl Ester; (R) -1-tert-Butoxycarbonyl pyrrolidine-3-methanol; (R)-N-Boc-pyrrolidine-3-methanol; (R)-tert-Butyl 3- (Hydroxymethyl) pyrrolidine-1-carboxylate; tert-Butyl (3R) -3- (hydroxymethyl) pyrrolidine-1-carboxylate; tert-Butyl (R) -3- (hydroxymethyl) pyrrolidine-1-carboxylate. Grades: Highly Purified. CAS No. 138108-72-2. Pack Sizes: 500mg. Molecular Formula: C10H19NO3, Molecular Weight: 201.26. US Biological Life Sciences. | Worldwide |
(R) -N-Ethyl-N- (1- (3- (trifluoromethyl) phenyl) propan-2-yl) benzamide Quick inquiry Where to buy | (R) -N-Ethyl-N- (1- (3- (trifluoromethyl) phenyl) propan-2-yl) benzamide is a benzoyl protected (R)-Fenfluramine (F247595), an anorexic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
(R)-N'-Nitrosonornicotine Quick inquiry Where to buy | (R)-N'-Nitrosonornicotine. Group: Biochemicals. Alternative Names: 3-[(2R)-1-Nitroso-2-pyrrolidinyl]pyridine; (R)-3-(1-Nitroso-2-pyrrolidinyl)pyridine. Grades: Highly Purified. CAS No. 61601-78-3. Pack Sizes: 5mg. Molecular Formula: C9H11N3O, Molecular Weight: 177.2. US Biological Life Sciences. | Worldwide |
(R)-N'-Nitrosonornicotine-d4 Quick inquiry Where to buy | (R)-N'-Nitrosonornicotine-d4. Group: Biochemicals. Alternative Names: 3-[(2R)-1-Nitroso-2-pyrrolidinyl]pyridine-d4; (R)-3-(1-Nitroso-2-pyrrolidinyl)pyridine-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(R)-Norapocodeine Quick inquiry Where to buy | (R)-Norapocodeine. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-10-methoxy-4H-dibenzo[de,g]quinolin-11-ol; N-Demethylapocodeine. Grades: Highly Purified. CAS No. 478-77-3. Pack Sizes: 1mg. Molecular Formula: C17H17NO2. US Biological Life Sciences. | Worldwide |
(R)-Nornicotine-d4 Quick inquiry Where to buy | (R)-Nornicotine-d4. Group: Biochemicals. Alternative Names: 3-(2R)-2-pyrrolidinylpyridine-d4; (+)-1'-demethylnicotine-d4; (R)-3-(2-pyrrolidinyl)pyridine; (+)-1'-Demethylnicotine; (+)-2-(3'-Pyridyl)pyrrolidine; (+)-Nornicotine; (R)-(+)-Nornicotine; (R)-(+)-Nornicotine. Grades: Highly Purified. CAS No. 1259761-67-5. Pack Sizes: 1mg. Molecular Formula: C9H8D4N2, Molecular Weight: 152.229999999999. US Biological Life Sciences. | Worldwide |
(R) -N- ( (R) -1- (naphthalen-1-yl) ethyl) -2- (3- (trifluoromethyl) phenyl) propan-1-amine Quick inquiry Where to buy | (R) -N- ( (R) -1- (naphthalen-1-yl) ethyl) -2- (3- (trifluoromethyl) phenyl) propan-1-amine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C22H22F3N, Molecular Weight: 357.41. US Biological Life Sciences. | Worldwide |
RO 20-1724, cAMP-specific Phosphodiesterase Inhibitor (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) Quick inquiry Where to buy | Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
RO-3306 Quick inquiry Where to buy | Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M. Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards. Group: Biochemicals. Alternative Names: (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one. Grades: Highly Purified. CAS No. 872573-93-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?OS?. US Biological Life Sciences. | Worldwide |
RO-3306, CDK 1 Inhibitor ((5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one) Quick inquiry Where to buy | Cell-permeable. A selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Arrests cell cycle at G1, S, and G2/M and induces apoptosis in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines, and suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Group: Biochemicals. Grades: Highly Purified. CAS No. 872573-93-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
Robotnikinin (N-2-acetamide) Quick inquiry Where to buy | Sonic hedgehog (Shh) signaling small molecule modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein. Group: Biochemicals. Alternative Names: N--2-acetamide. Grades: Highly Purified. CAS No. 1132653-79-2. Pack Sizes: 1mg. Molecular Formula: C25H27ClN2O4. US Biological Life Sciences. | Worldwide |
Rolitetracycline (Pyrrolidinyl methyl tetracycline, SQ 15659) Quick inquiry Where to buy | Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable. Group: Biochemicals. Alternative Names: (4S, 4aS, 5aS, 6S, 12aS) -4- (di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; 4- (Di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; Abricycline; Bristacin; N- (1-Pyrrolidinylmethyl) tetracycline; N- (Pyrrolidinomethyl) tetracycline; Pyrrolidinyl methyl tetracycline; Reverin; Rolitetracycline; SQ 15659; Superciclin; Synotodecin; Syntetrin; Tetraverin; Transcycline; Velacycline. Grades: Technical Grade. CAS No. 751-97-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 527.57. US Biological Life Sciences. | Worldwide |
Rosiglitazone Quick inquiry Where to buy | Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects on the cardiovascular system. Group: Biochemicals. Grades: Highly Purified. CAS No. 122320-73-4. Pack Sizes: 25mg, 100mg, 1g. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
Rosiglitazone maleate (BRL 49653, HSDB 7555, TDZ 01, Rosiglitazone XR, Avandia, PPAR Agonist X, PPARg Agonist IX) Quick inquiry Where to buy | Same activities as rosaglitazone but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects on the cardiovascular system. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs). Group: Biochemicals. Grades: Highly Purified. CAS No. 155141-29-0. Pack Sizes: 25mg, 100mg, 1g. Molecular Formula: C18H19N3O3S. C4H4O4. US Biological Life Sciences. | Worldwide |
Rosuvastatin Anhydro Lactone Quick inquiry Where to buy | Rosuvastatin Anhydro Lactone. Group: Biochemicals. Alternative Names: N- [5- [ (1E) -2- [ (2S) -3, 6-Dihydro-6-oxo-2H-pyran-2-yl] ethenyl] -4- (4-fluorophenyl) -6- (1- methyl ethyl) -2-pyrimidinyl] -N- methyl methanesulfonamide. Grades: Highly Purified. CAS No. 1246665-85-9. Pack Sizes: 5mg. Molecular Formula: C22H24FN3O4S, Molecular Weight: 445.51. US Biological Life Sciences. | Worldwide |
Rosuvastatin Isoamy Ester Quick inquiry Where to buy | Rosuvastatin Isoamy Ester. Group: Biochemicals. Alternative Names: (3R, 5S, 6E)-7-[4- (4-Fluorophenyl)-6- (1-methylethyl)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid 3-Methylbutyl Ester. Grades: Highly Purified. CAS No. 1197348-98-3. Pack Sizes: 1mg. Molecular Formula: C27H38FN3O6S, Molecular Weight: 551.669999999999. US Biological Life Sciences. | Worldwide |
Rosuvastatin tert-Butyl Ester Quick inquiry Where to buy | Rosuvastatin tert-Butyl Ester. Group: Biochemicals. Alternative Names: (3R, 5S, 6E)-7-[4- (4-Fluorophenyl)-6- (1-methylethyl)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester; (3R, 5S, 6E) -7-[4- (4-Fluorophenyl) -6-isopropyl-2-[ (methanesulfonyl) methylamino]pyrimidin-5-yl]-3, 5-dihydroxyhept-6-enoic Acid tert-Butyl Ester; tert-Butyl (6E) -7-[4- (4-fluorophenyl) -6-isopropyl-2-[methyl (methylsulfonyl) amino]pyrimidin-5-yl]- (3R, 5S) -3, 5-dihydroxyhept-6-enoate; tert-Butyl Rosuvastatin. Grades: Highly Purified. CAS No. 355806-00-7. Pack Sizes: 100mg. Molecular Formula: C26H36FN3O6S, Molecular Weight: 537.64. US Biological Life Sciences. | Worldwide |
Rotenone Quick inquiry Where to buy | Rotenone. Group: Biochemicals. Alternative Names: (-)-Rotenone; (-)-cis-Rotenone; 5' β-Rotenone; CFT Legumine; Cube-Pulver; Dactinol; Deril; Derrin; Derris; Derris (insecticide); Dri-kil; Liquid Derris; NSC 26258; NSC 8505; Nicouline; Noxfish; Paraderil; Ronone; Rotena; Rotenon; Rotenox; Rotocide; Tubatoxin; 1,2,12,12aα-Tetrahydro-2α-isopropenyl-8,9-dimethoxy-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aαH)-one; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: Highly Purified. CAS No. 83-79-4. Pack Sizes: 2.5g. Molecular Formula: C23H22O6, Molecular Weight: 394.42. US Biological Life Sciences. | Worldwide |
RPA 202248 Quick inquiry Where to buy | RPA 202248. Group: Biochemicals. Alternative Names: α-(Cyclopropylcarbonyl)-2-(methylsulfonyl)- β -oxo-4- (trifluoromethyl) benzenepropanenitrile. Grades: Highly Purified. CAS No. 143701-75-1. Pack Sizes: 5mg. Molecular Formula: C15H12F3NO4S, Molecular Weight: 359.32. US Biological Life Sciences. | Worldwide |
(R)-Pantoic Acid Sodium Salt Quick inquiry Where to buy | (R)-Pantoic Acid Sodium Salt. Group: Biochemicals. Alternative Names: (2R)-2,4-Dihydroxy-3,3-dimethylbutanoic Acid Sodium Salt; (R)-2,4-Dihydroxy-3,3-dimethylbutanoic Acid Monosodium Salt; D-Pantoic Acid Sodium Salt; Sodium (R)-Pantoate; Sodium D-Pantoate. Grades: Highly Purified. CAS No. 60979-68-2. Pack Sizes: 1g. Molecular Formula: C6H11NaO4, Molecular Weight: 170.14. US Biological Life Sciences. | Worldwide |
(R)-Phenprocoumon Quick inquiry Where to buy | (R)-Phenprocoumon. Group: Biochemicals. Alternative Names: (R)-4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one; (R)-(+)-3-(α-Ethylbenzyl)-4-hydroxy-coumarin; (+)-Phenprocoumon; (R)-(+)-Phenprocoumon. Grades: Highly Purified. CAS No. 599-27-9. Pack Sizes: 100mg. Molecular Formula: C18H16O3, Molecular Weight: 280.32. US Biological Life Sciences. | Worldwide |
rProtein A (4xZ), BioSeparation Quick inquiry Where to buy | BioSeparation rProtein A (4xZ) is a synthetic derivative of the native protein A molecule, produced by recombinant expression in E. coli and purified using a highly efficient, immunoglobulin-free process. rProtein A (4xZ) contains four identical copies of an Fc region-binding domain assembled in a single 29.88kD polypeptide, and can be coupled to solid supports to produce affinity media suitable for antibody capture and elution under standard conditions. Protein A is an immunoglobulin-binding cell wall protein naturally produced by Staphylococcus aureus and widely used as a generic ligand for the purification of monoclonal and recombinant antibodies. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
rProtein A Agarose Rapid Flow, BioSeparation Quick inquiry Where to buy | BioSeparation rProtein A Rapid Flow is an affinity medium coupled with Biomedal rProtein A (4xZ) and designed for immunoglobulin capture and purification. ProPure® rProtein A Rapid Flow medium is compatible with chromatography systems such as ÄKTA or FPLC, providing high binding capacity and a cost-efficient purification process. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
rProtein A-Cys, BioSeparation Quick inquiry Where to buy | BioSeparation rProtein A-Cys (4xZc) is a variant of rProtein A (4xZ) in which the C-terminal residue has been replaced with a cysteine residue that can be used for single-point coupling to solid supports, via the thioether bond, to produce affinity media suitable for antibody capture and elution. Like rProtein A (4xZ), rProtein A-Cys (4xZc) can also be attached to solid supports via multi-point coupling. rProtein A-Cys (4xZc) is produced by recombinant expression in E. coli and purified using a highly efficient, immunoglobulin-free process. rProtein A-Cys (4xZc) contains four identical copies of an Fc region-binding domain assembled in a single 29.87kD polypeptide. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
rProtein A LCL Agarose, BioSeparation Quick inquiry Where to buy | BioSeparation rProtein A LCL Agarose is an affinity medium coupled with rProtein A (4xZ) and designed for immunoglobulin capture and purification. This affinity medium can be packed in standard chromatography columns for antibody purification at any production scale. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
rProtein G Agarose Rapid Flow, BioSeparation Quick inquiry Where to buy | BioSeparation rProtein G Rapid Flow is an affinity medium coupled with rProtein G (3xC) and designed for immunoglobulin capture and purification. rProtein G Rapid Flow medium is compatible with chromatography systems such as ÄKTA or FPLC, providing high binding capacity and a cost-efficient purification process. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
rProtein G, Rapid Flow, Agarose, BioSeparation Quick inquiry Where to buy | BioSeparation rProtein A Rapid Flow are ready-to-use cartridges pre-packed with 1ml of rProtein A Rapid Flow and compatible with chromatography systems such as ÄKTA or FPLC, providing high binding capacity and a cost-efficient purification process. They are designed for rapid and cost-efficient immunoglobulin capture and purification. Group: Molecular Biology. US Biological Life Sciences. | Worldwide |
(R)-Pyrrolidine-2-carbonitrile Hydrochloride Quick inquiry Where to buy | (R)-Pyrrolidine-2-carbonitrile Hydrochloride. Group: Biochemicals. Alternative Names: (2R) -2-Pyrrolidinecarbonitri le Hydrochloride; (2R) -2-Pyrrolidinecarbonitri le Monohydrochloride. Grades: Highly Purified. CAS No. 675602-84-3. Pack Sizes: 250mg. Molecular Formula: C5H9ClN2, Molecular Weight: 132.59. US Biological Life Sciences. | Worldwide |
(R)-Ramelteon Quick inquiry Where to buy | (R)-Ramelteon. Group: Biochemicals. Alternative Names: N-[2-[(8R)-1, 6, 7, 8-Tetrahydro-2H-indeno[5, 4-b]furan-8-yl]ethyl]propanamide; (R)-N-[2-(1, 6, 7, 8-tetrahydro-2H-indeno[5, 4-b]furan-8-yl)ethyl]propanamide. Grades: Highly Purified. CAS No. 196597-27-0. Pack Sizes: 1mg. Molecular Formula: C16H21NO2, Molecular Weight: 259.339999999999. US Biological Life Sciences. | Worldwide |
(R)-Repaglinide Ethyl Ester Quick inquiry Where to buy | (R)-Repaglinide Ethyl Ester. Group: Biochemicals. Alternative Names: 2-Ethoxy-4-[2-[[ (1R) -3-methyl-1-[2- (1-piperidinyl) phenyl]butyl]amino]-2-oxoethyl]benzoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 147770-08-9. Pack Sizes: 1mg. Molecular Formula: C29H40N2O4, Molecular Weight: 480.64. US Biological Life Sciences. | Worldwide |
(R,R)-Hydroxy Des(boric Acid) Bortezomib Quick inquiry Where to buy | (R,R)-Hydroxy Des(boric Acid) Bortezomib. Group: Biochemicals. Alternative Names: N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
(R,R)-Hymeglusin Quick inquiry Where to buy | beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. Group: Biochemicals. Alternative Names: 1233A, F-244, L-659-699. Grades: Highly Purified. CAS No. 29066-42-0. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
(R, R) - [N, N'-Bis (3, 5-di-tert-butylsalicylidene) -1, 2-cyclohexanediamine] manganese (III) Chloride Quick inquiry Where to buy | (R, R) - [N, N'-Bis (3, 5-di-tert-butylsalicylidene) -1, 2-cyclohexanediamine] manganese (III) Chloride. Group: Biochemicals. Alternative Names: Jacobsen's Catalyst; Chloro[[2, 2'-[ (1R, 2R) -1, 2-cyclohexanediylbis[ (nitrilo-κ N) methylidyne]]bis[4, 6-bis (1, 1-dimethylethyl) phenolato-κ O]] (2-) ]manganese; (-) -Chloro{ (1R, 2R) -4, 4', 6, 6'-tetra-tert-butyl-2, 2'-[cyclohexane-1, 2-diylbis (nitrilomethylidyne) ]diphenolato}manganese (III) ; [SP-5-13- (1R-trans) ]-Chloro[[2, 2'-[1, 2-cyclohexanediylbis[ (nitrilo-κ N) methylidyne]]bis[4, 6-bis (1, 1-dimethylethyl) phenolato-κ O]] (2-) ]manganese; Chloro[[2, 2'-[1, 2-cyclohexanediylbis (nitrilomethylidyne) ]bis[4, 6-bis (1, 1-dimethylethyl) phenolato]] (2-) -N, N', O, O']manganese; (SP-5-13) -Chloro[[2, 2'-[ (1R, 2R) -1, 2-cyclohexanediylbis[ (nitrilo-κ N) methylidyne]]bis[4, 6-bis (1, 1-dimethylethyl) phenolato-κ O]] (2-) ]manganese. Grades: Highly Purified. CAS No. 138124-32-0. Pack Sizes: 5g. Molecular Formula: C36H52ClMnN2O2, Molecular Weight: 635.2. US Biological Life Sciences. | Worldwide |
(R)-Roscovitine Quick inquiry Where to buy | Potent and selective inhibitor of CDKs. More potent than olomoucine. Inhibits CDK1/cyclin B kinase (IC50 = 450nM), CDK2 (IC50 = 700nM) and CDK5/p35 (IC50 = 160nM). Inhibits M phase promoting factor (MPF) kinase activity. Arrests human fibroblasts in G1 phase. Antitumor compound. Activates the mitogen-activated protein kinase pathway. Targets both the p53 and NF-kappaB pathways. Has effects on calcium channel gating. Prevents DNA damage-induced cyclin A1 upregulation. Apoptosis inducer. As CYC202 in phase I clinical trials. Group: Biochemicals. Alternative Names: (2R)-2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; (R)-2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine; CYC 202; (R)-Roscovitine; R-Roscovitine; Roscovitin; Seliciclib. Grades: Highly Purified. CAS No. 186692-46-6. Pack Sizes: 1mg, 5mg, 50mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
(R,R)-Sertraline Quick inquiry Where to buy | (R,R)-Sertraline. Group: Biochemicals. Alternative Names: (1R,4R)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine; (1R-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-Naphthalenamine; (1R,4R)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine; CP 51973. Grades: Highly Purified. CAS No. 79617-98-4. Pack Sizes: 10mg. Molecular Formula: C17H17Cl2N, Molecular Weight: 306.23. US Biological Life Sciences. | Worldwide |
(R)-Rutheniumdiacetate-(DM-SEGPHOS) Quick inquiry Where to buy | (R)-Rutheniumdiacetate-(DM-SEGPHOS). Group: Biochemicals. Alternative Names: (OC-6-22) -Bis (acetato-κ O, κ O') [1, 1'- (4R) -[4, 4'-bi-1, 3-benzodioxole]-5, 5'-diylbis[1, 1-bis (3, 5-dimethylphenyl) phosphine-κ P]]ruthenium. Grades: Highly Purified. CAS No. 944450-49-1. Pack Sizes: 100mg. Molecular Formula: C50H50O8P2Ru, Molecular Weight: 941.95. US Biological Life Sciences. | Worldwide |
RS-1 Quick inquiry Where to buy | High affinity RAD51 activator (Kd range = 48-107nM, value depends on cofactors present). Enhances homologous recombination activity of hRAD51. Enhances homology-directed repair and increases CRISPR-mediated knock-in efficiencies in vitro and in vivo.RS-1 is an activator of DNA repair protein RAD51 (Kd = 48-107 for human RAD51 with different cofactors present).1 It stimulates homologous strand assimilation activity at least 5- to 11-old, enhancing homologous recombination activity of hRAD51.1 RS-1 is a potent enhancer of CRISPR-mediated genome editing, increasing homology directed repair 3- to 6-fold.2 It is used to increase CRISPR-mediated knock-in efficiencies in vitro and in vivo.3,2,4. Group: Biochemicals. Alternative Names: 4-Bromo-N- (4-bromophenyl) -3- [ [ (phenylmethyl) amino] sulfonyl] benzamide. Grades: Highly Purified. CAS No. 312756-74-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??Br?N?O?S, Molecular Weight: 524.23. US Biological Life Sciences. | Worldwide |
(R,S)-1-Tosyl Glycerol-d5 Quick inquiry Where to buy | Protected, labeled Glycerol. Group: Biochemicals. Alternative Names: 1-Tosyloxy-2,3-propanediol-d5; 2,3-Dihydroxypropyl Tosylate-d5; p-Toluenesulfonic Acid Glyceryl Ester-d5; 1-p-Toluenesulfonate Glycerol-d5; 1,2,3-Propanetriol 1- (4-Methyl Benzene sulfonate) -d5. Grades: Highly Purified. CAS No. 928623-32-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
(R, S) -3-[ (Tert-butyldimethylsilyl) oxy]-2-methyl-butanoic Acid Methyl Ester Quick inquiry Where to buy | (R, S) -3-[ (Tert-butyldimethylsilyl) oxy]-2-methyl-butanoic Acid Methyl Ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 155897-72-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
(R)-Telaprevir Quick inquiry Where to buy | (R)-Telaprevir is an enantiomer of Telaprevir , an inhibitor of the hepatitis C virus NS3-4A protease. Group: Biochemicals. Alternative Names: (1S, 3aR, 6aS) -2- [ (2S) -2- [ [ (2S) -2-cyclohexyl-2- [ (2-pyrazinylcarbonyl) amino] acetyl] amino] -3, 3-dimethyl-1-oxobutyl] -N- [ (1R) -1- [2- (cyclopropylamino) -2-oxoacetyl] butyl] octahydrocyclopenta [c] pyrrole-1-carboxamide. Grades: Purified. CAS No. 923270-50-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(R)-tert-Butyl 2-(tert-Butoxycarbonylamino)-5-oxo-5-phenylpentanoate Quick inquiry Where to buy | (R)-tert-Butyl 2-(tert-Butoxycarbonylamino)-5-oxo-5-phenylpentanoate. Group: Biochemicals. Alternative Names: α -[[ (1, 1-Dimethylethoxy) carbonyl]amino]-δ -oxo-benzenepentanoic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 1260616-34-9. Pack Sizes: 250mg. Molecular Formula: C20H29NO5, Molecular Weight: 363.45. US Biological Life Sciences. | Worldwide |
(R)-tert-Butyl 2-(tert-Butoxycarbonylamino)-5-oxo-5-phenylpentanoate-d5 Quick inquiry Where to buy | (R)-tert-Butyl 2-(tert-Butoxycarbonylamino)-5-oxo-5-phenylpentanoate-d5. Group: Biochemicals. Alternative Names: α -[[ (1, 1-Dimethylethoxy) carbonyl]amino]-δ -oxo-benzenepentanoic Acid 1,1-Dimethylethyl Ester-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C20H24D5NO5, Molecular Weight: 368.48. US Biological Life Sciences. | Worldwide |
RTI-111 Quick inquiry Where to buy | RTI-111. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(3, 4-Dichlorophenyl)-8-methyl-, 8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo, exo)]-3-(3, 4-Dichlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-111. Grades: Highly Purified. CAS No. 150653-91-1. Pack Sizes: 10mg. Molecular Formula: C16H20Cl3NO2 , Molecular Weight: 364.69. US Biological Life Sciences. | Worldwide |
RTI-111-d3 Quick inquiry Where to buy | RTI-111-d3. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(3, 4-Dichlorophenyl)-8-(methyl-d3)-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo, exo)]-3-(3, 4-Dichlorophenyl)-8-(methyl-d3)-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-111-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C16H17D3Cl3NO2 , Molecular Weight: 367.71. US Biological Life Sciences. | Worldwide |
(R)-Timolol Quick inquiry Where to buy | (R)-Timolol is an antihypertensive agent that increases ocular blood flow and reduces intraocular pressure. (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain. Group: Biochemicals. Alternative Names: (+)-Timolol; (R)-(+)-Timolol; L 714465; d-Timolol; (R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol; (+)-1-(tert-Butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol. Grades: Highly Purified. CAS No. 26839-76-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
(R)-(+)-Timolol Maleate Quick inquiry Where to buy | Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 26839-77-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
R-(+)-Tolterodine Quick inquiry Where to buy | A muscarinic receptor antagonist. Used in the treatment of urinary incontinence. Group: Biochemicals. Alternative Names: 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol; (R)-(+)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine; (R)-Tolterodine; Kabi 2234; PNU 200583; Tolterodine. Grades: Highly Purified. CAS No. 124937-51-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Rugulosin Quick inquiry Where to buy | Antibiotic. Antibacteriophage. Antiviral. Mycotoxin. DNA replication, transcription and repair inhibitor. Antibacterial. RNA polymerase and ribonuclease H inhibitor. Insecticidal. Cytotoxic. HIV-1 integrase inhibitor. Shows anti-MRSA (methicillin-resistant Staphylococcus aureus) activity. Source:Isolated from Penicillium sp. Group: Biochemicals. Alternative Names: (+)-Rugulosin, NSC 160880, NSC 249990, Radicalisin. Grades: Highly Purified. CAS No. 23537-16-8. Pack Sizes: 250ug, 1mg. Molecular Formula: C30H22O10, Molecular Weight: 542.5. US Biological Life Sciences. | Worldwide |