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D-[UL-13C6]glucose
D-[UL-13C6]glucose. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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Duloxetine Hydrochloride
An antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence. Group: Biochemicals. Alternative Names: (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine Hydrochloride; LY-248686. Grades: Highly Purified. CAS No. 136434-34-9. Pack Sizes: 10mg. US Biological Life Sciences.
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Dupracine
Dupracine. Group: Biochemicals. Alternative Names: (2E)-3-(3,4-Dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-2-propenoic Acid; Drupacin. Grades: Highly Purified. CAS No. 12772-83-7. Pack Sizes: 500mg. Molecular Formula: C14H16O3, Molecular Weight: 232.28. US Biological Life Sciences.
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D-Valacyclovir Hydrochloride
Acyclovir impurity. The D-Valine ester prodrug of Acyclovir. Group: Biochemicals. Alternative Names: D-Valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl Ester Hydrochloride; Acyclovir D-Valinate Hydrochloride; D-VACV Hydrochloride. Grades: Highly Purified. CAS No. 124832-28-6. Pack Sizes: 50mg, 500mg. US Biological Life Sciences.
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D-Valganciclovir-d5 Hydrochloride
D-Valganciclovir-d5 Hydrochloride. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine-d5 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H18D5ClN6O5, Molecular Weight: 398.85. US Biological Life Sciences.
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D-Valganciclovir Hydrochloride
D-Valganciclovir Hydrochloride. Group: Biochemicals. Alternative Names: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester D-Valine Hydrochloride. Grades: Highly Purified. CAS No. 1393911-57-3. Pack Sizes: 10mg. Molecular Formula: C14H23ClN6O5, Molecular Weight: 390.82. US Biological Life Sciences.
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D-Xylose-1,2,3,4,5,5'-C-d6
D-Xylose-1,2,3,4,5,5'-C-d6. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C5H4D6O5, Molecular Weight: 156.169999999999. US Biological Life Sciences.
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D-Xylose-1-C-d
D-Xylose-1-C-d. Group: Biochemicals. Grades: Highly Purified. CAS No. 288846-89-9. Pack Sizes: 10mg. Molecular Formula: C5H9DO5, Molecular Weight: 151.139999999999. US Biological Life Sciences.
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D-Xylose-2-C-d
D-Xylose-2-C-d. Group: Biochemicals. Grades: Highly Purified. CAS No. 288846-91-3. Pack Sizes: 10mg. Molecular Formula: C5H9DO5, Molecular Weight: 151.139999999999. US Biological Life Sciences.
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D-Xylose-5-C-d2
D-Xylose-5-C-d2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C5H9DO5, Molecular Weight: 151.139999999999. US Biological Life Sciences.
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Dynasore
Dynamin GTPase inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Group: Biochemicals. Grades: Highly Purified. CAS No. 304448-55-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H14N2O4. 0.5H2O. US Biological Life Sciences.
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E-1-Methylthio-1-propene
E-1-Methylthio-1-propene. Group: Biochemicals. Alternative Names: (1E)-1-(Methylthio)-1-propene; (E)-Methyl 1-propenyl Sulfide. Grades: Highly Purified. CAS No. 42848-06-6. Pack Sizes: 10mg. Molecular Formula: C4H8S, Molecular Weight: 88.17. US Biological Life Sciences.
Intermediate in the preparation of Ramelteon. Group: Biochemicals. Grades: Highly Purified. CAS No. 196597-61-2. Pack Sizes: 5mg. US Biological Life Sciences.
(E)-2-(2-Aminoethyl)but-2-enoic Acid Hydrochloride. Group: Biochemicals. Alternative Names: Vigabatrin Related Compound B. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C6H12ClNO2, Molecular Weight: 165.62. US Biological Life Sciences.
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(E)-2-Thiopheneacrylic Acid
(E)-2-Thiopheneacrylic Acid is used in the synthesis of anti-HIV HEPT analogs. Also used in the synthesis of benzimidazole and caffeine (C080100) analogs as inhibitors of monoamine oxidase B. Group: Biochemicals. Alternative Names: (E)-3-(Thiophen-2-yl)-2-propenoic Acid; (E)-3-(Thiophen-2-yl)acrylic Acid; trans-3-Thiopheneacrylic Acid; (E)-2-Thiopheneacrylic Acid; (E)-3-(2-Thienyl)-2-propenoic Acid. Grades: Highly Purified. CAS No. 15690-25-2. Pack Sizes: 10g. US Biological Life Sciences.
Intermediate in the preparation of (E)-Cefdinir. Group: Biochemicals. Alternative Names: (E) -α -[ (Triphenylmethoxy) imino]-2-[ (triphenylmethyl) amino]-4-thiazoleacetic Acid. Grades: Highly Purified. CAS No. 69689-81-2. Pack Sizes: 25mg. US Biological Life Sciences.
(E)-3-(3,4-Bis(benzyloxy)phenyl)-2-methylacrylic Acid Ethyl Ester is an benzyl protected intermediate in the synthesis of Carbidopa (C175915), an inhibitor of aromatic amino acid decarboxylase. Group: Biochemicals. Alternative Names: (E)-ethyl 3-(3,4-bis(benzyloxy)phenyl)-2-methylacrylate; α-Methyl-3,4-dibenzyloxy-2-propanoic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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(E)-3,7-Dimethyl-2-octenoic Acid Ethyl Ester
(E)-3,7-Dimethyl-2-octenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: Ethyl (E)-3,7-Dimethyl-2-octenoate. Grades: Highly Purified. CAS No. 59060-59-2. Pack Sizes: 1g. Molecular Formula: C12H22O2, Molecular Weight: 198.3. US Biological Life Sciences.
(E) -4-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-2-butenoic Acid Ethyl Ester is an protected intermediate in the synthesis of 4-Amino-γ-butyrolactones via asymmetrical synthesis. Group: Biochemicals. Alternative Names: Ethyl (E) -4-[ (tert-Butyldimethylsilyl) oxy]but-2-enoate; (2E) -4-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-2-butenoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 94844-37-8. Pack Sizes: 100mg. US Biological Life Sciences.
(E) -4-[4-[Bis (2-chloroethyl) amino]phenyl]-3-butenoic Acid. Group: Biochemicals. Alternative Names: 3,4-Dehydro Chlorambucil. Grades: Highly Purified. CAS No. 73027-06-2. Pack Sizes: 5mg. Molecular Formula: C14H17Cl2NO2, Molecular Weight: 302.2. US Biological Life Sciences.
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(E)-4-Hydroxycrotonoic Acid Ethyl Ester
(E)-4-Hydroxycrotonoic Acid Ethyl Ester is an intermediate in the preparation of unusual amino acids that are potential Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors. Group: Biochemicals. Alternative Names: Ethyl trans-4-Hydroxy-2-butenoate; (2E)-4-Hydroxy-2-butenoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 10080-68-9. Pack Sizes: 250mg. US Biological Life Sciences.
(E) -4- ( (tert-Butyldimethylsilyl) oxy) but-2-enoic Acid Benzyl Ester is an protected intermediate in the synthesis of Clavulanic Acid (C563750), an β-lactamase inhibitor that is added to amoxicillin (A634235) to increase its effectiveness. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
(E)-5,6-Dihydro-4-hydroxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one is a kawapyrones isolated from Fijian kawa. Group: Biochemicals. Alternative Names: 5,6-Dihydro-4-hydroxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one. Grades: Highly Purified. CAS No. 62378-65-8. Pack Sizes: 250mg. US Biological Life Sciences.
Impurity of Ebastine (E320000), which is a nonsedating type histamine H1-receptor antagonist. Antihistaminic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C33H41NO2, Molecular Weight: 483.68. US Biological Life Sciences.
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Ebrotidine.
Ebrotidine. Group: Biochemicals. Alternative Names: [N (E) ] -N- [ [ [2- [ [ [2- [ (Aminoiminomethyl) amino] -4-thiazolyl] methyl] thio] ethyl] amino] methylene] -4-bromo Benzene sulfonamide; Ebrodin; FI 3542; Ulsanic. Grades: Highly Purified. CAS No. 100981-43-9. Pack Sizes: 50mg. Molecular Formula: C14H17BrN6O2S3, Molecular Weight: 477.42. US Biological Life Sciences.
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Ebselen
Glutathione peroxidase mimetic. Peroxynitrite scavenger. Anti-inflammatory Antioxidant. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor. Antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 60940-34-3. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C13H9NOSe. US Biological Life Sciences.
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(+)-Echimidine
(+)-Echimidine. Group: Biochemicals. Alternative Names: 1,5-Dideoxy-2-C-methyl-3-C-[[[(1R,7aR)-2,3,5,7a-tetrahydro-1-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-1H-pyrrolizin-7-yl]methoxy]carbonyl]-L-threo-pentitol; Echimidine. Grades: Highly Purified. CAS No. 520-68-3. Pack Sizes: 1mg. Molecular Formula: C20H31NO7, Molecular Weight: 397.46. US Biological Life Sciences.
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Echinocandin B
Echinocandin B is the major analogue of a family of lipopeptides isolated from several species of Aspergillus, reported in 1974. Echinocandin B is a potent antifungal and acts by inhibition of the synthesis of b(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Group: Biochemicals. Grades: Highly Purified. CAS No. 54651-05-7. Pack Sizes: 1mg. US Biological Life Sciences.
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(E)-Cinnamoyl Chloride
(E)-Cinnamoyl Chloride is used in the preparation of aminodihydroquinoline analogs displaying anticancer activity. It is also used in the preparation of lysergol and related derivatives for use as antibacterials. Group: Biochemicals. Alternative Names: (2E)-3-Phenyl-2-propenoyl Chloride; (2E)-3-Phenylprop-2-enoyl Chloride; (E)-3-Phenyl-2-propenoyl chloride; (E)-Cinnamoyl Chloride; trans-3-Phenyl-2-propenoyl chloride; trans-Cinnamic Acid Chloride; trans-Cinnamoyl Chloride. Grades: Highly Purified. CAS No. 17082-09-6. Pack Sizes: 5g. US Biological Life Sciences.
(E, E, E) -[ (12-Bromo-3, 7, 11-trimethyl-2, 6, 10-dodecatrienyl) oxy]methyl]benzene
Used in the preparation of Vitamin K2. Group: Biochemicals. Alternative Names: [ [ [ (2E, 6E, 10E) -12-Bromo-3, 7, 11-trimethyl-2, 6, 10-dodecatrienyl] oxy] methyl] benzene. Grades: Highly Purified. CAS No. 71135-56-3. Pack Sizes: 2.5mg. US Biological Life Sciences.
P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Eltrombopag Amide
Eltrombopag Amide. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H23N5O3, Molecular Weight: 441.48. US Biological Life Sciences.
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Eltrombopag Ethyl Ester
Eltrombopag Ethyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C27H26N4O4, Molecular Weight: 470.52. US Biological Life Sciences.
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Eltrombopag Glucuronide
Eltrombopag Glucuronide. Group: Biochemicals. Alternative Names: 1-[3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene-3-14C]hydrazinyl]-2'-hydroxy[1,1'-biphenyl]-3-carboxylate]- β-D-glucopyranuronic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C31H30N4O10, Molecular Weight: 618.59. US Biological Life Sciences.
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Eltrombopag Methyl Ester
Eltrombopag Methyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1246929-01-0. Pack Sizes: 5mg. Molecular Formula: C26H24N4O4, Molecular Weight: 456.49. US Biological Life Sciences.
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EM574
Shows strong gastrointestinal motor stimulating (GMS) activity. Motilin receptor agonist. Stimulates smooth muscle cell contraction. Stimulates cholinergic neurons in a non-vagal pathway. Enhances gastrointestinal contractile activity and accelerates gastric emptying. Shows orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, ghrelin receptor). Group: Biochemicals. Grades: Highly Purified. CAS No. 110480-13-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C39H69NO12. US Biological Life Sciences.
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Emetine Hydrochloride Hydrate
Hydrochloride salt of Emetine is the principal alkaloid of ipecac, the ground roots of Uragoga ipecacuanha. Group: Biochemicals. Alternative Names: 3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[(1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl]-2H-Benzo[a]quinolizine Dihydrochloride Hydrate; (2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine Dihydrochloride Hydrate; 6',7',10,11-Tetramethoxyemetan Dihydrochloride; Emetine Dihydrochloride Hydrate; (-)-Emetine Dihydrochloride; Emetine Hydrochloride Hydrate; Hemometina Hydrate; l-Emetine Dihydrochloride Hydrate. Grades: Highly Purified. CAS No. 7083-71-8. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??Cl?N?O? xH?O, Molecular Weight: 553.56. US Biological Life Sciences.
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EMPA
EMPA. Group: Biochemicals. Alternative Names: N-Ethyl-2-[ (6-methoxy-3-pyridinyl) [ (2-methylphenyl) sulfonyl]amino]-N- (3-pyridinylmethyl) -acetamide. Grades: Highly Purified. CAS No. 680590-49-2. Pack Sizes: 10mg. Molecular Formula: C23H26N4O4S, Molecular Weight: 454.54. US Biological Life Sciences.
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Enalaprilat Butyl tert-Butyl Diester
Protected Enalaprilat (E555375) a metabolite of Enalapril (E555245). Group: Biochemicals. Alternative Names: N- [ (1S) -3-phenyl-1- [butyloxycarbonyl] propyl] -L-alanyl-L-proline 1,1-Dimethylethyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Enalaprilat tert-Butyl Ester
Protected Enalaprilat (E555375) a metabolite of Enalapril (E555245). Group: Biochemicals. Alternative Names: 1-[N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl]-L-proline tert-Butyl Ester. Grades: Highly Purified. CAS No. 674796-29-3. Pack Sizes: 10mg. US Biological Life Sciences.
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Enalapril tert-Butyl Ester
Protected Enalapril (E555250), an antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor. Group: Biochemicals. Alternative Names: N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 108428-39-3. Pack Sizes: 25mg. US Biological Life Sciences.
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endo-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-ol
endo-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-ol. Group: Biochemicals. Alternative Names: 3α-Hydroxytrop-6-ene; 6,7-Dehydrotropine; Tropenol; 6,7-Didehydro-1αH,5αH-Tropan-3α-ol. Grades: Highly Purified. CAS No. 20513-09-1. Pack Sizes: 250mg. Molecular Formula: C8H13NO, Molecular Weight: 139.19. US Biological Life Sciences.
Enniatins are a family of depsipeptides produced several Fusarium species. The enniatins have been shown to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex and has previously not been available for investigation. Group: Biochemicals. Alternative Names: 2-(N-Methyl-L-valine) Enniatin A. Grades: Highly Purified. CAS No. 4530-21-6. Pack Sizes: 1mg. US Biological Life Sciences.
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Enniatin A (Lateritin I)
Enniatins are a family of depsipeptides produced several Fusarium species. The enniatins have been shown to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A is one of four major analogs of the enniatin complex and has previously not been available for investigation. Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms dimeric structures that transport monovalent ions across the membrane (especia...:Fusarium sp. MST-FP1765. Group: Biochemicals. Alternative Names: Lateritin I; Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl]; N-(D-2-Hydroxy-3-methylbutyryl)-N-methyl-Isoleucine Trimol. Cyclic Ester; 1,7,13-Trioxa-4,10,16-triazacyclooctadecane Cyclic Peptide Deriv.;Cyclo(D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl). Grades: Highly Purified. CAS No. 2503-13-1. Pack Sizes: 500ug. Molecular Formula: C??H??N?O?, Molecular Weight: 681.9. US Biological Life Sciences.
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Enniatin B
Enniatins are a complex of family produced several Fusarium species. The enniatins have been shown to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin B is the most studied of four major analogues of the enniatin complex. Group: Biochemicals. Grades: Highly Purified. CAS No. 917-13-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Enniatin B1 (2-(N-Methyl-L-isoleucine) Enniatin B)
Enniatins are a family of depsipeptides produced several Fusarium species. The enniatins have been shown to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin B1 is one of four major analogues of the enniatin complex and has not previously been available for investigation. Group: Biochemicals. Alternative Names: 2-(N-Methyl-L-isoleucine) Enniatin B. Grades: Highly Purified. CAS No. 19914-20-6. Pack Sizes: 1mg. US Biological Life Sciences.
Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3nm for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits alpha-synuclein aggregation in an in vitro assay; blocks alpha-synuclein-induced cell death in PC-12 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 130929-57-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Entacapone-3-sulfate Sodium Salt
Entacapone-3-sulfate Sodium Salt. Group: Biochemicals. Alternative Names: (E)-2-Cyano-N,N-diethyl-3-[4-hydroxy-3-nitro-5-(sulfooxy)phenyl]-2-propenamide Sodium Salt. Grades: Highly Purified. CAS No. 158069-72-8. Pack Sizes: 5mg. Molecular Formula: C14H14N3NaO8S, Molecular Weight: 407.33. US Biological Life Sciences.
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ent-Dorzolamide
ent-Dorzolamide. Group: Biochemicals. Alternative Names: 4R,6R-Dorzolamide; (4R-trans)-4-(ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide. Grades: Highly Purified. CAS No. 120279-95-0. Pack Sizes: 2.5mg. Molecular Formula: C10H16N2O4S3, Molecular Weight: 324.44. US Biological Life Sciences.