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Heterocyclic Organic Compound. Alternative Names: Nonyl hydride. CAS No. 111-84-2. Molecular formula: C9H20. Mole weight: 128.25. Catalog: ACM111842.
Nocodazole
Nocodazole (Oncodazole) is a rapidly-reversible inhibitor of microtubule. Nocodazole binds to β-tubulin and disrupts microtubule assembly/disassembly dynamics, which prevents mitosis and induces apoptosis in tumor cells. Nocodazole inhibits Bcr-Abl, and activates CRISPR/Cas9. Group: Inhibitors. Alternative Names: [5-(2-THIENYLCARBONYL)-1H-BENZIMIDAZOL-2-YL]CARBONIC ACID, METHYL ESTER;METHYL[5-(2-THIENYLCARBONYL)-1H-BENZIMADAZOL-2-YL]CARBAMATE;METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMIDAZOL-2-YL)CARBAMATE;METHYL [5-(2-THIENYLCARBONYL)-1H-BENZ-IMIDAZOLE-2-YL]-CARBAMATE;METHYL-(5-[2-THIENYLCARBONYL]-1H-BENZIMODAZOL-2YL)-CARBAMATE;METHYL N-(5-THENOYL-2-BENZIMIDAZOLYL)CARBAMATE; NOCODAZOLE; R 17934. CAS No. 31430-18-9. Molecular formula: C14H11N3O3S. Mole weight: 301.32. Appearance: powder. Purity: 0.9966. Density: 1.49. Catalog: ACM31430189.
n-Octylamine HydroBromide
Organohalide based perovskites have emerged as an important class of material for solar cell applications. The variations/substitution in organohalide cations and anions is employed for the optimization of the band gap, carrier diffusion length, and power conversion efficiency of perovskites based solar cells. Group: Bromide salts. Alternative Names: n-Octylammonium Bromide; OABr. CAS No. 14846-47-0. Molecular formula: C8H19N HBr. Mole weight: 210.16 g/mol. Appearance: White to Almost white powder to crystal. Purity: >98.0%(T). IUPACName: octan-1-amine;hydrobromide. Canonical SMILES: CCCCCCCCN.Br. Catalog: ACM14846470-1.
Nogalamycin is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer. Group: Inhibitors. Alternative Names: antibiotic205t3; nogalomycin; NOGALAMYCIN; NOGALAMYCIN,STREPTOMYCES NOGALATER. CAS No. 1404-15-5. Molecular formula: C39H53NO16. Mole weight: 787.8. Appearance: Solid. Purity: 0.96. IUPACName: nogalamycin. Canonical SMILES: CC1C (C (C (C (O1)OC2CC (C (C3=C2C (=C4C (=C3)C (=O)C5=C6C (=CC (=C5C4=O)O)C7 (C (C (C (C (O6)O7)O)N (C)C)O)C)O)C (=O)OC) (C)O)OC) (C)OC)OC. Density: 1.49g/cm³. Catalog: ACM1404155.
Nolatrexed dihydrochloride (AG 337) is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme, with a Ki of 11 nM for human thymidylate synthase. Nolatrexed dihydrochloride (AG 337) induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity. Group: Inhibitors. Alternative Names: Nolatrexed dihydrochloride. CAS No. 152946-68-4. Molecular formula: C14H12N4OS?2(HCl). Mole weight: 357.26. Appearance: Tan Solid. Purity: ≥98%. Canonical SMILES: [H]Cl. O=C1N=C (N)NC2=C1C (SC3=CC=NC=C3)=C (C)C=C2. [H]Cl. Density: g/cm³. Catalog: ACM152946684.
Norathyriol (Mangiferitin) is a natural metabolite of Mangifera. Norathyriol inhibits α-glucosidase in a noncompetitive manner with an IC50 of 3.12?μM. Norathyriol inhibits PPARα, PPARβ, and PPARγ with IC50s of 92.8 μM, 102.4 μM, and 153.5 μM, respectively. Antioxidant, anticancer, antimicrobial, anti-inflammatory, anti-bacterial activities. Group: Inhibitors. Alternative Names: norathyriol; 1, 3, 6, 7-Tetrahydroxy-9H-xanthen-9-one; 1, 3, 6, 7-Tetrahydroxyxanthone; Mangiferitin; rathyriol; 9H-Xanthen-9-one, 1,3,6,7-tetrahydroxy-. CAS No. 3542-72-1. Molecular formula: C13H8O6. Mole weight: 260.2. Purity: 0.9983. Catalog: ACM3542721.
Norbornyl methacrylate
Heterocyclic Organic Compound. Alternative Names: NORBORNYL METHACRYLATE;Norboronyl methacrylate. CAS No. 111965-24-3. Molecular formula: C11H16O2. Mole weight: 180.24. Catalog: ACM111965243.
Nori Complex
Nori is the Japanese name for edible seaweed species of the red algae genus Pyropia. It contains various active ingredients including amino acids, proteins and polysaccharides. Nori Complex is especially effective in hair treatments providing strength and vitality, while also reducing its frizz. Suitable to be formulated into any kind of hair treatment mainly aimed at reducing frizz and adding strength and vitality. Uses: Hair masks, hair shampoos, hair conditioners, but also useful in creams and lotions. Group: Hair actives. CAS No. 7732-18-5 / 56-81-5 / 223751-76-6 / 39300-88-4 / 532-32-1 / 24634-61-5. Catalog: CI-HC-0229.
Heterocyclic Organic Compound. Alternative Names: 3-Dibenzo[b,e]thiepin-11(6H)-ylidene-N-methyl-. CAS No. 1154-09-2. Molecular formula: C18H19NS. Mole weight: 281.42. Appearance: Pale Yellow Solid. Purity: 0.96. IUPACName: (3E)-3-(6H-benzo[c][1]benzothiepin-11-ylidene)-N-methylpropan-1-amine. Density: 1.161g/cm³. Catalog: ACM1154092.
Norway Spruce Extract
Extract obtained from Picea Excelsa (Norway Spruce) needles and shoots. Contains 20% extract dissolved in water and glycerin. Has tonic, cleansing and moisturizing properties. Uses: Soaps, cleansers and bath producsts. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 91770-69-3 / 122-99-6. Appearance: Light to medium amber liquid, characteristic odor. Catalog: CI-SC-0931.
Nosiheptide
Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth. Group: Inhibitors. Alternative Names: Nosiheptide ; N- [1- (Aminocarbonyl) ethenyl] -2- [ (11S, 14Z, 21S, 23S, 29S) -14-ethylide ne -9, 10, 11, 12, 13, 14, 19, 20, 21, 22, 23, 24, 26, 33, 35, 36-hexadeca hydro-3, 23-di hydroxy-11- [ (1R) -1- hydroxyethyl] -31- methyl -9, 12, 19, 24, 33, 43-hexaoxo-30, 32-imino-8, 5: 18, 15: 40, 37-tri nitri lo-21, 36- ( [2, 4] -endo-thiazolomethanimino) -5H, 15H, 37H-pyrido [3, 2-w] [2, 11, 21, 27, 31, 7, 14, 17] benzoxatetrathiatri azacyclohexatri acontin-2-yl] -4-thiazolecarboxamide ; Nosiheptide VETRANAL;priMofax. CAS No. 56377-79-8. Molecular formula: C51H43N13O12S6. Mole weight: 1222.38. Appearance: Solid. Purity: 0.9705. Canonical SMILES: OC1=C (C2=NC (C (NC (C (N) =O) =C) =O) =CS2) N=C (C3=CSC (C4NC (C5=CSC (C (CC (C (OCC6=C7C (C) =C (NC7=CC=C6) C (SC4) =O) =O) O) NC (C8=CSC (/C (NC (C (C (O) C) NC (C9=CSC%10=N9) =O) =O) =C\C) =N8) =O) =N5) =O) =N3) C%10=C1. Catalog: ACM56377798.
Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity. Group: Inhibitors. CAS No. 303-81-1. Molecular formula: C31H36N2O11. Mole weight: 612.628. Catalog: ACM303811.
N-Palmitoyl-Phytosphingosine
Sphingolipids. Alternative Names: N-hexadecanoylphytosphingosine. CAS No. 111149-09-8. Molecular formula: C34H69NO4. Mole weight: 555.916. Purity: 98%+. Catalog: ACM111149098.
NS-11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle. NS11021 enhances erectile responses in rats. Group: Activators. Alternative Names: NS-11021; NS 11021; NS11021. CAS No. 956014-19-0. Molecular formula: C16H9BrF6N6S. Mole weight: 511.24. Appearance: Solid powder. Purity: >98%. IUPACName: N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-thiourea. Canonical SMILES: S=C (NC1=CC (C (F) (F)F)=CC (C (F) (F)F)=C1)NC2=CC=C (Br)C=C2C3=NNN=N3. Catalog: ACM956014190.
N-((S)-1-Benzylpyrrolidin-3-yl)acetamide
Heterocyclic Organic Compound. Alternative Names: (S)-(-)-1-BENZYL-3-ACETAMIDOPYRROLIDINE;(S)-1-BENZYL-3-ACETYLAMINO PYRROLIDINE;(S)-N-Benzyl-3-AcetylaminoPyrrolidine;(S)-(-)-1-BENZYL-3-ACETAMIDOPYRROLIDINE , EE 99%;(S)-(-)-1-BENZYL-3-ACETAMIDOPYRROLIDINE, 98%, EE 99%;N-((S)-1-Benzylpyrrolidin-3-yl)acet. CAS No. 114636-30-5. Molecular formula: C13H18N2O. Mole weight: 218.29. Appearance: white or cream-colored solid. Purity: 0.96. IUPACName: N-(1-benzylpyrrolidin-3-yl)acetamide. Canonical SMILES: CC(=O)NC1CCN(C1)CC2=CC=CC=C2. Density: 1.1g/cm³. Catalog: ACM114636305.
Nsc 625987
NSC 625987 is a specific and high-affinity CDK4 inhibitor with an IC50 of 0.2 μM for CDK4:cyclin D1. NSC 625987 shows >500-fold selectivity for CDK4 over CDK2. Group: Inhibitors. CAS No. 141992-47-4. Molecular formula: C15H13NO2S. Mole weight: 271.339. Purity: >98 %. Catalog: ACM141992474.
Nsc 663284
NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM). Group: Inhibitors. CAS No. 383907-43-5. Molecular formula: C15H16ClN3O3. Mole weight: 321.762. Appearance: Solid. Purity: >99 %. Canonical SMILES: O=C (C (Cl)=C1NCCN2CCOCC2)C3=C (N=CC=C3)C1=O. Catalog: ACM383907435.
N-tert-Butylacrylamide (nTBA) belongs to the class of hydrophobic acrylamides which can be synthesized by Ritter reaction and optimized by using N-tert-butyl acetate and acetic acid. Uses: Ntba is temperature sensitive monomers that can be potentially used in drug delivery systems, dewatering of proteins, and immobilization of cells. it can be used in the preparation of poly(ntba) based copolymeric hydrogels for bovin serum albumin. Group: Polymer/macromoleculeacrylamide monomers. Alternative Names: N -(1,1-Dimethylethyl)-2-propenamide, N -t -Butylacrylamide. CAS No. 107-58-4. Molecular formula: C7H13NO. Mole weight: 127.19 g/mol. Appearance: White to Almost White Powder to Crystal. Purity: 98.0%(GC)(T). IUPACName: N-tert-butylprop-2-enamide. Canonical SMILES: CC(C)(C)NC(=O)C=C. ECNumber: 203-505-6. Catalog: ACM-MO-107584.
For a synthetic protocol using NMP initiators, contributed by Prof. Karen Wooley, please visit our technology spotlight. Uses: Block copolymer synthesis using a commercially available nmp inititator. Alternative Names: 2,2,5-Trimethyl-3-(1-phenylethoxy)-4-phenyl-3-azahexane, Alkoxyamine NMP initiator. CAS No. 227000-59-1. Molecular formula: C22H31NO. Mole weight: 325.49. Appearance: Colorless liquid. Canonical SMILES: CC (C)C (N (OC (C)c1ccccc1)C (C) (C)C)c2ccccc2. Density: 0.968 g/mL at 25 °C. Catalog: ACM227000591-1.
N,N-ditetradecyl-polysarcosine-25 Polysarcosine (pSar, a polypeptoid based on the amino acid sarcosine) lipids have become a promising alternative to PEGylated lipids. When formulating LNPs, pSar lipids of varying polymeric chain lengths have been used to tune physiochemical properties such as particle size, morphology, and internal structure. Aside from being able to change the physical nature of the LNP, pSar LNPs have also proven to be an excellent mRNA transfection agent. When compared to similar LNPs formulated with PEGylated lipids, LNPs formulated with pSar lipids exhibited a more robust mRNA transfection potency while also showing an improved safety profile. Group: Polymers & polymerizable lipids. CAS No. 2847775-93-1. Molecular formula: C103H184N26O25. Mole weight: 2186.76. Purity: >99%. Catalog: ACM2847775931.
N-tetradecyl-pSar25
N-tetradecyl polysarcosine-25 One promising alternative to PEGylated lipids is a polypeptide-lipid conjugate based on the amino acid sarcosine (pSar). pSar lipids of varying polymeric chain lengths have been used to tune the physical properties of LNPs such as particle size, morphology, and internal structure. Group: Polymers & polymerizable lipids. CAS No. 120468-71-5. Molecular formula: C89H156N26O25. Mole weight: 1990.38. Purity: >99%. Catalog: ACM120468715.
NTNCB HCl
NTNCB is a selective, non-peptide competitive NPY Y5 antagonist. NTNCB potently antagonizes NPY inhibition of forskolin-stimulated cAMP. NTNCB Displays some affinity for cloned human D2 and α2C receptors (Ki values are 63 and 100 nM respectively). Group: Antagonists. Alternative Names: NTNCB HCl; NTNCB hydrochloride. CAS No. 191931-56-3. Molecular formula: C25H34ClN3O4S. Mole weight: 508.07. Appearance: Solid powder. Purity: >98%. IUPACName: 2-Nitro-N- [ [trans-4- [ [ [ (1, 2, 3, 4-tetrahydro-2-naphthalenyl) methyl] amino] methyl] cyclohexyl] methyl] benzenesulfonamide hydrochloride. Canonical SMILES: O=S (C1=CC=CC=C1[N+] ([O-])=O) (NC[C@H]2CC[C@H] (CNCC3CC4=C (C=CC=C4)CC3)CC2)=O. [H]Cl. Catalog: ACM191931563.
N-Vinylformamide (NVF) is a class of N-vinylamide that is a precursor to amide and amine functional polymer. It has attractive properties that include high reactivity in polymerization and hydrolysis. Uses: Nvf can be used in the free radical polymerization formation of poly(nvf) with a molecular weight ranging from 104 to 106. Group: Polymer/macromoleculevinyl monomers. Alternative Names: n-ethenyl-formamid. CAS No. 13162-05-5. Molecular formula: C3H5NO. Mole weight: 71.08 g/mol. Purity: 0.98. Canonical SMILES: [H]C(=O)NC=C. Density: 1.014 g/mL at 25 °C (lit.). Catalog: ACM-MO-13162055.
NVR 3-778 is the first capsid assembly modulator (CAM) that has demonstrated antiviral activity in hepatitis B virus (HBV)-infected patients. NVR 3-778 inhibited the generation of infectious HBV DNA-containing virus particles with a mean antiviral 50% effective concentration (EC50) of 0.40?μM in HepG2.2.15 cells. The antiviral profile of NVR 3-778 indicates pan-genotypic antiviral activity and a lack of cross-resistance with nucleos(t)ide inhibitors of HBV replication. Group: Inhibitors. Alternative Names: NVR 3 778; NVR3 778; NVR-3-778; K-89; K 89; K89; NVR3778; NVR 3778; NVR-3778. CAS No. 1445790-55-5. Molecular formula: C18H16F4N2O4S. Mole weight: 432.39. Appearance: Solid powder. Purity: >98%. IUPACName: 4-Fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide. Canonical SMILES: O=C (NC1=CC (F)=C (F)C (F)=C1)C2=CC=C (F)C (S (=O) (N3CCC (O)CC3)=O)=C2. Catalog: ACM1445790555.
NVS-PAK1-1
NVS-PAK1-1 is a specific allosteric PAK1 inhibitor. Group: Inhibitors. Alternative Names: NVS-PAK1-1; NVSPAK11; NVS PAK1 1. CAS No. 1783816-74-9. Molecular formula: C23H25ClF3N5O. Mole weight: 479.93. Appearance: Solid powder. Purity: >98%. IUPACName: 3(S)-[2-Chloro-5-(2,2-difluoro-ethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino]-pyrrolidine-1-carboxylic acid isopropylamide. Canonical SMILES: O=C (N1C[C@@H] (NC2=NC3=CC (F)=CC=C3N (CC (F)F)C4=CC=C (Cl)C=C42)CC1)NC (C)C. Catalog: ACM1783816749.
Nylon 12 is a nylon polymer. It is made from omega-aminolauric acid or laurolactam monomers, each of which has 12 carbon atoms, hence the name "nylon 12". It is one of several nylon polymers. Uses: Nylon 12 has a wide range of applications as a polyamide additive. nylon 12 is mainly used for packaging material films in the food industry and sterilization films and bags in the pharmaceutical and medical fields. when added to polyethylene films, it improves water vapor permeability and aroma impermeability. it is also available in sheet and sintered powder for metal coating. Group: Biomaterials. Alternative Names: Polylauryllactam. CAS No. 24937-16-4. Molecular formula: (C12H23NO)n. Mole weight: 591.95. Canonical SMILES: O=C1CCCCCCCCCCCN1. Density: 1.01 g/mL at 25 °C (lit.). Catalog: ACM24937164-2.