Alfa Chemistry is an ISO 9001:2015 Certified Supplier of various building blocks, reagents, catalysts, nanomaterials, reference materials, and research chemicals. In-stock products can be shipped quickly.
8-Keto-berberine is a natural product that is extracted from the plant Berberis aristata. It has been used as a reference material for HPLC standards, and is used in the screening of secondary metabolites and phytochemicals. 8-Keto-berberine has been shown to be bioactive, with antioxidant and anti-inflammatory properties. It also inhibits protein kinase C (PKC) activity, which may lead to its anti-cancer effects. 8-Keto-berberine is a secondary metabolite isolated from plants, and can be found in the CAS Registry Number 81397-08-2. Group: Other alkaloids. CAS No. 81397-08-2. Molecular formula: C20H17NO5. Mole weight: 351.4 g/mol. Canonical SMILES: CN1CCOC(C1)C2=NC=C(C=C2)Br.Cl. Catalog: ACM81397082.
Heterocyclic Organic Compound. CAS No. 114865-68-8. Catalog: ACM114865688.
8-Methoxy-4-methylbenzo[g]coumarin
Alfa Chemistry offers high-purity 8-Methoxy-4-methylbenzo[g]coumarin products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: The unique fluorescence properties of a coumarin analog, 8-methoxy-4-methylbenzo[g]coumarin (mmbc). mmbc is almost nonfluorescent in aprotic solvents, whereas it strongly fluoresces at long wavelengths in protic solvents. in the protic solvents, mmbc has a large stokes shift. these unique features are convenient for developments of new fluorogenic sensors and devices. Group: Heterocyclic organic compound. Alternative Names: 8-Methoxy-4-methyl-2H-naphtho[2,3-b]pyran-2-one. CAS No. 69169-71-7. Molecular formula: C15H12O3. Mole weight: 240.26. Appearance: Light orange to Yellow to Green powder to crystal. Purity: >98.0%(HPLC)(N). IUPACName: 8-methoxy-4-methylbenzo[g]chromen-2-one. Canonical SMILES: CC1=CC(=O)OC2=C1C=C3C=CC(=CC3=C2)OC. Density: 1.243g/cm³. Catalog: ACM69169717-1.
8-Oxa-3-thiabicyclo[5.1.0]octane(9ci)
Heterocyclic Organic Compound. CAS No. 115187-02-5. Catalog: ACM115187025.
8-Oxoepiberberine
8-Oxoepiberberine is a protoberberine alkaloid that inhibits polymerization of DNA, RNA and proteins. It also has an inhibitory effect on the replication of pertussis toxin. 8-Oxoepiberberine has been shown to have anti-cancer properties in vitro and in vivo. This drug inhibits tumor growth by inhibiting cell proliferation and inducing apoptosis. 8-Oxoepiberberine also inhibits the growth of primary tumors in mice without affecting normal cells or healthy tissue. This drug is also effective against lung cancer cells and has been shown to be safe for use in humans. Group: Other alkaloids. CAS No. 19716-60-0. Molecular formula: C20H17NO5. Mole weight: 351.4 g/mol. Canonical SMILES: COC1=C (C=C2C (=C1)CCN3C2=CC4=C (C3=O)C5=C (C=C4)OCO5)OC. Catalog: ACM19716600-1.
9,10-Anthracenedicarboxylic acid
9,10-Anthracenedicarboxylic acid (H2L) is an anthracene based dicarboxylic compound, which has a larger conjugating π-system that enables the development of fluorescent materials. It has interesting magnetic and luminescent properties. It can be used as a bridging carboxylic acid ligand with a steric bulk due to the presence of its anthracene ring. Group: Heterocyclic organic compound. Alternative Names: H2ADC. CAS No. 73016-08-7. Molecular formula: C16H10O4. Mole weight: 266.25. Appearance: Yellow solid. Purity: 0.96. IUPACName: anthracene-9,10-dicarboxylic acid. Canonical SMILES: C1=CC=C2C (=C1)C (=C3C=CC=CC3=C2C (=O)O)C (=O)O. Catalog: ACM73016087-1.
Alfa Chemistry offers 9-(2,6-Dimethylphenyl)-10-methylacridinium Perchlorate products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: It can be used as a solar energy source. Group: Organic catalysts. CAS No. 1276539-32-2. Molecular formula: C22H20ClNO4. Mole weight: 397.86. Appearance: Light yellow to Yellow to Orange powder to crystal. Catalog: ACM1276539322.
Heterocyclic Organic Compound. Alternative Names: 9-FLUOROBENZO[K]FLUORANTHENE;9-fluoro-benzo(k)fluoranthen. CAS No. 113600-15-0. Molecular formula: C20H11F. Mole weight: 270.3. Density: 1.349 g/cm³. Catalog: ACM113600150.
9-Hydroxy-10(E),12(E)-octadecadienoic acid
Fatty Acids and Ester Derivatives. Alternative Names: trans-9-HODE; 9(R,S)-Hydroxy-10(E),12(E)-octadecadienoic acid. CAS No. 115185-06-3. Molecular formula: C18H32O3. Mole weight: 296.44. Purity: 98%+. Catalog: ACM115185063.
9-Mesityl-10-methylacridinium perchlorate
Alfa Chemistry offers 9-Mesityl-10-methylacridinium Perchlorate products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: It can be used as a solar energy source. Group: Heterocyclic organic compound. Alternative Names: 10-Methyl-9-(2,4,6-trimethylphenyl)acridinium Perchlorate. CAS No. 674783-97-2. Molecular formula: C23H22ClNO4. Mole weight: 411.88. Appearance: Light yellow to Amber to Dark green powder to crystal. Purity: >98.0%(HPLC). IUPACName: 10-methyl-9-(2,4,6-trimethylphenyl)acridin-10-ium;perchlorate. Catalog: ACM674783972.
9-Mesityl-2,7,10-trimethylacridinium Perchlorate
Alfa Chemistry offers 9-Mesityl-2,7,10-trimethylacridinium Perchlorate products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: It can be used as a solar energy source. Group: Other materials. CAS No. 1216909-33-9. Molecular formula: C25H26ClNO4. Mole weight: 439.94. Appearance: White to Yellow to Green powder to crystal. Purity: >98.0%(HPLC). IUPACName: 2,7,10-trimethyl-9-(2,4,6-trimethylphenyl)acridin-10-ium;perchlorate. Canonical SMILES: CC1=CC2=C (C=C1)[N+] (=C3C=CC (=CC3=C2C4=C (C=C (C=C4C)C)C)C)C. [O-]Cl (=O) (=O)=O. Catalog: ACM1216909339.
9-Methoxycamptothecin
9-Methoxycamptothecin (MCPT), isolated from Camptotheca acuminata, has antitumor activities through topoisomerase inhibition. 9-Methoxycamptothecin (MCPT) induces strong G2/M arrest and apoptosis in cancer. Group: Inhibitors. Alternative Names: (4S)-10-Methoxy-4α-ethyl-4β-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. CAS No. 39026-92-1. Molecular formula: C21H18N2O5. Mole weight: 378.4. Appearance: Solid. Purity: 95%+. Canonical SMILES: CC[C@@]1 (C2=C (COC1=O)C (N3C (C4=NC5=CC=CC (OC)=C5C=C4C3)=C2)=O)O. Catalog: ACM39026921.
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM) and myosin light chain kinase (MLCK) (Ki=7.4 μM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively. Group: Inhibitors. Alternative Names: A3, Hydrochloride, A3 hydrochloride, IN1547, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide, HCl, A-3HYDROCHLORIDE, A1980_SIGMA, SCHEMBL3503907, CHEMBL1255867, CTK7E9088, OR0890T, MolPort-001-756-823, CCG-222331, LP01027, NCGC00094317-01, 3B3-053691, N-(2-Aminoethyl)-5-chloronaphthalene-1-sulphonamide hydrochloride, N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, HYDROCHLORIDE, 78957-85-4. CAS No. 78957-85-4. Molecular formula: C12H14Cl2N2O2S. Mole weight: 321.22. Purity: 0.96. IUPACName: N-(2-aminoethyl)-5-chloronaphthalene-1-sulfonamide;hydrochloride. Catalog: ACM78957854.
A-485
A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs. SPR data indicates potent binding to p300 (KD=15 nM). In PC-3 cells A-485 reduces H3K27ac with IC50 of 73 nM while not affecting H3K9ac levels. Inhibition of cellular proliferation is observed in several cancer cell types, most notably AR+ prostate, multiple myeloma, and NHL. A-486 is a suitable control with 1000-fold higher IC50 in the p300 TR-FRET assay. Group: Inhibitors. Alternative Names: A-485; A 485; A485. CAS No. 1889279-16-6. Molecular formula: C25H24F4N4O5. Mole weight: 536.48. Appearance: Solid powder. Purity: >98%. IUPACName: N-(4-fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide. Canonical SMILES: O=C (N1CC (N ([C@H] (C (F) (F)F)C)CC2=CC=C (F)C=C2)=O)[C@@]3 (OC1=O)CCC4=CC (NC (NC)=O)=CC=C43. Catalog: ACM1889279166.
Prurisol, also known as abacavir hydroxyacetate and KM-133, is potentially for the treatment of plaque psoriasis. Group: Others. Alternative Names: KM-133; KM133; KM 133; Prurisol; Abacavir acetate; Abacavir hydroxyacetate. CAS No. 1446418-48-9. Molecular formula: C16H20N6O3. Mole weight: 344.37. Appearance: Solid powder. Purity: >98%. IUPACName: ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl 2-hydroxyacetate. Canonical SMILES: O=C (OC[C@@H]1C=C[C@H] (N2C=NC3=C (NC4CC4)N=C (N)N=C23)C1)CO. Catalog: ACM1446418489.
Aba Silicone Polyol Copolymer
The combination of polysiloxane and propylene oxide side chains can provide excellent lubricity and low surface tension, thereby improving the wettability, leveling and fluidity of solvent-based coatings. Uses: It mainly used as pigment dispersant and glass cleaner. Group: Siloxane polymers. CAS No. 102783-01-7. Appearance: Clear to slightly hazy, colorless to amber liquid. Catalog: ACM102783017.
abciximab
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors. Group: Inhibitors. CAS No. 143653-53-6. Purity: 0.99966. Catalog: ACM143653536.
Abecarnil
Abecarnil is a beta carboline and a partial benzodiazepine-receptor agonist that has demonstrated promise as an anxiolytic agent. It may be useful in treating generalized anxiety disorder. Group: Agonists. Alternative Names: Abecarnil; ZK 112119; ZK-112119; ZK112119. CAS No. 111841-85-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. Appearance: Solid powder. Purity: >98%. IUPACName: 6-(Benzyloxy)-4-(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylic acid 1-methylethyl ester. Canonical SMILES: O=C (C1=C (COC)C2=C (C=N1)NC3=C2C=C (OCC4=CC=CC=C4)C=C3)OC (C)C. Catalog: ACM111841851.
Abediterol
Abediterol, also known as LAS100977, is a novel potent, long-acting inhaled β(2)-adrenoceptor agonist in development for the treatment of asthma and chronic obstructive pulmonary disease. Abediterol shows subnanomolar affinity for the human β(2)-adrenoceptor and a functional selectivity over β(1)-adrenoceptors higher than that of formoterol and indacaterol in both a cellular model with overexpressed human receptors and isolated guinea pig tissue. Abediterol is a full agonist at the human β(2)-adrenoceptor (E(max) = 91 ± 5% of the maximal effect of isoprenaline). The potency and onset of action that abediterol shows in isolated human bronchi (EC(50) = 1.9 ± 0.4 nM; t½ onset=7-10 min) is not significantly different from that of formoterol, but its duration of action (t½ ~ 690 min) is similar to that of indacaterol. Group: Agonists. Alternative Names: LAS100977; LAS-100977; LAS 100977; Abediterol. CAS No. 915133-65-2. Molecular formula: C25H30F2N2O4. Mole weight: 460.52. Appearance: Solid powder. Purity: >98%. IUPACName: 5-((1R)-2-((6-(2,2-Difluoro-2-phenylethoxy)hexyl)amino)-1-hydroxyethyl)-8- hydroxyquinolin-2(1H)-one. Canonical SMILES: O=C1NC2=C (C ([C@@H] (O)CNCCCCCCOCC (F) (F)C3=CC=CC=C3)=CC=C2O)C=C1. Catalog: ACM915133652.
Ablukast
Ablukast is a leuktriene receptor antagonist that acts as an anti-asthmatic. Group: Antagonists. Alternative Names: Ablukast; Ro 23-3544; Ro-23-3544; Ro23-3544; Ro 233544; Ro-233544; Ro233544; Ro 23-3544/000. CAS No. 96566-25-5. Molecular formula: C28H34O8. Mole weight: 498.57. Appearance: Solid powder. Purity: >98%. IUPACName: 2H-1-Benzopyran-2-carboxylic acid, 6-acetyl-7-((5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl)oxy)-3,4-dihydro-, (+-)-. Canonical SMILES: O=C (C1CCC2=CC (C (C)=O)=C (OCCCCCOC3=CC=C (C (C)=O)C (O)=C3CCC)C=C2O1)O. Catalog: ACM96566255-1.
(+)-Absouline
Other Alkaloids. CAS No. 112513-33-4. Mole weight: 286.37. Purity: 95%+. Catalog: ACM112513334.
ABT-100
ABT-100 is an orally bioavailable farnesyltransferase inhibitor. ABT-100 inhibited proliferation of cells in vitro carrying oncogenic H-Ras (EJ-1 bladder; IC(50) 2.2 nmol/L), Ki-Ras (DLD-1 colon, MDA-MB-231 breast, HCT-116 colon, and MiaPaCa-2 pancreatic; IC(50) range, 3.8-9.2 nmol/L), and wild-type Ras (PC-3 and DU-145; IC(50), 70 and 818 nmol/L, respectively) as well as clonogenic potential. ABT-100 shows 70% to 80% oral bioavailability in mice. ABT-100 regressed EJ-1 tumors (2-12.5 mg/kg/d s.c., every day for 21 days) and showed significant efficacy in DLD-1, LX-1, MiaPaCa-2, or PC-3 tumor-bearing mice (6.25-50 mg/kg/d s.c. once daily or twice daily orally). Group: Inhibitors. Alternative Names: ABT100; ABT 100; ABT-100; A367074; A 367074; A-367074. CAS No. 450839-40-4. Molecular formula: C27H19F3N4O3. Mole weight: 504.46. Appearance: White solid powder. Purity: >98%. IUPACName: (S)-6-(2-(4-cyanophenyl)-2-hydroxy-2-(1-methyl-1H-imidazol-5-yl)ethoxy)-4'-(trifluoromethoxy)-[1, 1'-biphenyl]-3-carbonitrile. Canonical SMILES: N#CC1=CC (C2=CC=C (OC (F) (F)F)C=C2)=C (OC[C@] (O) (C3=CC=C (C#N)C=C3)C4=CN=CN4C)C=C1. Catalog: ACM450839404.
ABT-384
ABT-384 is an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. Group: Inhibitors. Alternative Names: ABT-384; ABT 384; ABT384. CAS No. 868623-40-9. Molecular formula: C25H34F3N5O2. Mole weight: 493.58. Appearance: Solid powder. Purity: >98%. IUPACName: 4-[[2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoyl]amino]adamantane-1-carboxamide. Canonical SMILES: O=C (C12CC3C (NC (C (N4CCN (C5=NC=C (C (F) (F)F)C=C5)CC4) (C)C)=O)C (C2)CC (C3)C1)N. Catalog: ACM868623409.
Acacia Extract
Extract obtained from Acacia stems (Acacia Senegel). Contains 20% extract dissolved in water and glycerin. Has excellent sooting and anti-irritant properties. Uses: Creams and lotions, masks and shampoos. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 90387-99-8 / 122-99-6. Appearance: Colorless to pale yellow liquid, characteristic odor. Catalog: CI-SC-0927.