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d(+)-Carnitinenitrile chloride,97
Heterocyclic Organic Compound. Alternative Names: (3-cyano-2-hydroxypropyl) trimethyl-, chloride, d-ammoniu; 3-cyano-2-hydroxy-n, n, n-trimethyl-, chloride, (s) -1-propanaminiu; d- (3-cyano-2-hydroxypropyl) trimethylammoniumchloride; d-carnitinnitrilchlorid; D (+) -CARNITINENITRILE CHLORIDE, 97. CAS No. 1116-95-6. Molecular formula: C7H15ClN2O. Mole weight: 178.6598. Catalog: ACM1116956.
dCBP-1
dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and can abolish the enhancer that drives MYC oncogene expression. As an efficient degrader of this unique class of acetyltransferases, dCBP-1 is a useful tool alongside domain inhibitors for dissecting the mechanism by which these factors coordinate enhancer activity in normal and diseased cells. Group: Others. Alternative Names: dCBP-1; dCBP 1; dCBP1. CAS No. 2484739-25-3. Molecular formula: C51H63F2N11O10. Mole weight: 1028.13. Appearance: Solid powder. Purity: >98%. IUPACName: 5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1Hpyrazol-4-yl)-1(2H)-quinolinyl]-1-[1-[15-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-4-piperidinyl]-1,4,6,7-tetrahydro-N-methyl-. Canonical SMILES: O=C (N1CCC (N (C2CCN (C (CCOCCOCCOCCOCCNC3=CC4=C (C (N (C (CC5) C (NC5=O) =O) C4=O) =O) C=C3) =O) CC2) N=C6N7CCCC8=C7C=C (C (F) F) C (C9=CN (C) N=C9) =C8) =C6C1) NC. Catalog: ACM2484739253.
DCJTB
Alfa Chemistry offers high-purity DCJTB products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Uses: Red dopant for white organic light emitting diodes (oleds). Group: Organic light emitting diode (oled). Alternative Names: 4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran. CAS No. 200052-70-6. Molecular formula: C30H35N3O. Mole weight: 453.62 g/mol. Appearance: Orange to Brown to Dark red powder to crystal. Purity: >98.0%(HPLC)(N). IUPACName: 2-[2-tert-butyl-6-[(E)-2-(4,4,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-7-yl)ethenyl]pyran-4-ylidene]propanedinitrile. Canonical SMILES: CC (CC1) (C)C2=C (N1CCC3 (C)C)C3=CC (/C=C/C4=CC (C=C (C (C) (C)C)O4)=C (C#N)C#N)=C2. Catalog: ACM200052706.
DC-S239
DC-S239 is a potent and selective histone methyltransferase SET7 inhibitor. Group: Inhibitors. Alternative Names: DC-S239; DC S239; DCS239. CAS No. 303141-21-1. Molecular formula: C15H15N3O5S. Mole weight: 349.36. Appearance: Solid powder. Purity: >98%. IUPACName: Ethyl 2-Amino-4-methyl-5-((3-nitrophenyl)carbamoyl)-thiophene-3-carboxylate. Canonical SMILES: O=C (C1=C (N)SC (C (NC2=CC=CC ([N+] ([O-])=O)=C2)=O)=C1C)OCC. Catalog: ACM303141211.
D-Cysteine,s,2-dimethyl-(9ci)
Heterocyclic Organic Compound. Alternative Names: D-Cysteine, S,2-dimethyl- (9CI). CAS No. 111003-28-2. Molecular formula: C5H11NO2S. Mole weight: 149.21134. Catalog: ACM111003282.
DDD85646
DDD85646 is a T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. DDD85646 has potent activity against the enzyme (IC(50) = 2 nM) and T. brucei (EC(50) = 2 nM) in culture. DDD85646 has good oral pharmacokinetics and cures rodent models of peripheral HAT infection. DDD85646 provides an excellent tool for validation of T. brucei NMT as a drug target for HAT as well as a valuable lead for further optimization. Group: Others. Alternative Names: DDD85646; DDD-85646; DDD 85646. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.42. Appearance: Solid powder. Purity: >98%. IUPACName: 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide. Canonical SMILES: O=S (C1=C (Cl)C=C (C2=CC (N3CCNCC3)=NC=C2)C=C1Cl) (NC4=C (C)N (C)N=C4C)=O. Catalog: ACM1215010551.
Dde-Lys(Fmoc)-OH
Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Also available Fmoc-Lys(Dde)-OH 852057. This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Dde-Lys(Fmoc)-OH, N-α-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-ε-Fmoc-L-lysine. CAS No. 156648-40-7. Mole weight: 532.63. Catalog: ACM156648407.
DEACETYL-10-OXO-7-EPI-TAXOL, 10-
Yew Tree. Group: Taxanes. CAS No. 105377-71-7. Mole weight: 809.85. Appearance: Off white Powder. Catalog: ACM105377717.
DEACETYL-7-XYLOSLYTAXOL, 10-
Yew Tree. Group: Taxanes. CAS No. 90332-63-1. Mole weight: 943.98. Appearance: White powder. Purity: 95%/ 93.7%. Catalog: ACM90332631.
Deacetylakuammiline
Deacetylakuammiline is a monoterpenoid indole alkaloid that has been shown to have anticancer activity. It is structurally related to strictine and apocynin, which are also found in the Apocynaceae family of plants. Deacetylakuammiline has been shown to be effective against leukemia cells, colorectal carcinoma, and colon cancer cells. The anticancer properties of deacetylakuammiline may be due to its ability to reduce blood pressure and inhibit platelet aggregation. Deacetylakuammiline has shown cytotoxic effects on tumor cells by binding and inhibiting the enzyme ATP synthase, which is essential for energy production in the cell. This binding leads to increased reactive oxygen species production, which can cause DNA damage or apoptosis (cell death). Group: Indole alkaloids. Alternative Names: RhazimolErcinaminine. CAS No. 1897-30-9. Molecular formula: C21H24N2O3. Mole weight: 352.43 g/mol. Canonical SMILES: C / C=C \ 1 / CN2CC [C@@]34C5=CC=CC=C5N=C3 [C@@H]2C [C@@H]1C4 (CO) C (=O) OC. Catalog: ACM1897309.
Debromohymenialdisine is a pyrrole alkaloid. Group: Heterocyclic organic compound. Alternative Names: (Z)-2-Debromohymenialdisine. CAS No. 75593-17-8. Molecular formula: C11H11N5O2. Mole weight: 245.24. Appearance: Yellow Solid. Purity: 95%+. IUPACName: (4Z)-4-(2-Amino-5-oxo-1H-imidazol-4-ylidene)-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one. Canonical SMILES: C1CNC (=O)C2=C (C1=C3C (=O)NC (=N3)N)C=CN2. Density: 1.82g/cm³. Catalog: ACM75593178.
Decamethylcyclopentasiloxane
Decamethylcyclopentasiloxane (D5) is an organosilicon compound with the formula [(CH3)2SiO]5. It is a colorless and odorless liquid that is slightly volatile. The compound is classified as a cyclomethicone. Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products. It is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage. It is also used as part of silicone based personal lubricants. D5 is considered an emollient. In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products. Uses: It widely used in cosmetics and body care products, such as skin care, sunscreen,makeup, hair conditioning products, good compatibility with most of the alcohol and other cosmetic solvents. be directly used as the carrier, the main raw material, also can be used as an additive; and be used in aqueous systems by the method of emulsification. Group: Siloxanes. Alternative Names: Cyclopentasiloxane, decamethyl-; DecaMethylcyclopentasiloxane; 2, 2, 4, 4, 6, 6, 8, 8, 10, 10-decamethyl-1, 3, 5, 7, 9, 2, 4, 6, 8, 10-pentaoxapentasilecane; D5 Cyclomethicone. CAS No. 541-02-6. Molecular formula: C10H30O5Si5. Mole weight: 370.77 g/mol. Appearance: Liquid. Purity: ≥99%. IUPACName: Decamethylcyclopentasiloxane. Density: 0.958. ECNumber: 208-764-9. Catalog: ACM541026.
Decyl alcohol appears as a clear colorless liquid with a sweet fat-like odor. Flash point 180°F. Less dense than water and insoluble in water. Vapors are heavier than air.; Liquid; Liquid; Liquid; Liquid; COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.;colourless liquid/floral, waxy, fruity odour. Group: Fatty alcohols. Alternative Names: Capric alcohol. CAS No. 112-30-1. Molecular formula: C10H22O. Mole weight: 158.27. Appearance: Liquid. Purity: 99%+. IUPACName: decan-1-ol. Canonical SMILES: CCCCCCCCCCO. Density: 0.84 at 68 °F (USCG, 1999);0.8297 g/cu cm at 20 °C;0.83 g/cm³;Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.01;0.826-0.831. ECNumber: 203-956-9; 266-367-6; 287-621-2; 253-173-1; 613-644-8. Catalog: ACM112301.
Decyl glucoside is a mild, plant-derived surfactant that is commonly used in personal care and household products as a cleansing agent, foaming agent, and emulsifier. It is a natural, non-ionic surfactant made from renewable raw materials such as coconut oil and corn starch. Decyl glucoside is biodegradable, eco-friendly, and gentle on the skin, making it ideal for use in natural and organic cosmetics, shampoos, body washes, lotions, and other skincare products. It is also commonly used in household cleaning products such as dish soaps, laundry detergents, and surface cleaners due to its ability to effectively clean dirt and grime without causing harm to the environment. Uses: 1. decyl glucoside is commonly used as a surfactant in personal care and household products. 2. it is a mild and gentle surfactant, suitable for use in baby products such as shampoos and body washes. 3. decyl glucoside is often used in formulations as a primary or co-surfactant to improve foam quality and stability. 4. it shows excellent biodegradability, making it an environmentally friendly opti. Group: Natural nonionics alkylpolyglucosides. CAS No. 54549-25-6. Appearance: clear, colorless to pale yellow liquid or gel-like substance. Catalog: CI-HC-0032.
Decyl Glucoside Sodium Lauroyl Lactylate
All natural, non-ionic mild surfactant blend consisting of decyl glucoside and sodium lauroyl lactylate. Decyl glucoside is made from coconut and corn starch. Sodium lauroyl lactylate is the sodium salt of lactic acid and an effective emulsifier widely used in foods. Uses: Body washes, shampoos, bubble baths, cleansing lotions, hand soaps, baby products, cream rinses. Group: Natural nonionics alkylpolyglucosides. CAS No. 58846-77-8 / 68515-73-1 / 141464-42-8 / 13557-75-0. Appearance: Clear to slightly hazy yellow to amber viscous liquid, mild odor. Catalog: CI-HC-0033.
Decyl Oleate
Lubricant emollient for cosmetic applications. It is soluble in most hydrophobic solvents such as silicones, esters, mineral oils, vegetable oils and mineral spirits. Uses: Skin and hair care products, color cosmetics. Group: Non-ionic surfactants. Alternative Names: 9-Octadecenoic acid, decyl ester, (Z)-. CAS No. 3687-46-5. Molecular formula: C28H54O2. Mole weight: 422.73. Appearance: Clear yellow liquid. IUPACName: Decyl (Z)-octadec-9-enoate. Canonical SMILES: CCCCCCCCCCOC(=O)CCCCCCC/C=C\CCCCCCCC. Density: 0.862g/ml. ECNumber: 222-981-6. Catalog: ACM3687465.
Deferasirox-d4 is the deuterium labeled Deferasirox. Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload. Group: Inhibitors. Alternative Names: 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid-d4; Exjade-d4; ICL-670-d4; ICL-670A-d4; CGP-72670-d4. CAS No. 1133425-75-8. Molecular formula: C21H11D4N3O4. Mole weight: 377.39. Appearance: Yellow Solid. Canonical SMILES: OC1=C (C=CC=C1)C2=NC (C3=C (C=CC=C3)O)=NN2C4=C ([2H])C ([2H])=C (C ([2H])=C4[2H])C (O)=O. Catalog: ACM1133425758.
Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Group: Inhibitors. Alternative Names: UNII-0X50BP49M1, Dehydroandrographolide succinate, 14-Deoxy-11,12-didehydroandrographolide bis(hemisuccinate), 786593-06-4, Butanedioic acid, 1-(((1R,2R,4aR,5R,8aS)-2-(3-carboxy-1-oxopropoxy)-5-((1E)-2-(2,5-dihydro-2-oxo-3-furanyl)ethenyl)decahydro-1,4a-dimethyl-6-methylene-1-naphthalenyl)methyl) ester. CAS No. 786593-06-4. Molecular formula: C28H36O10. Mole weight: 532.582. Appearance: Solid. Purity: 0.96. IUPACName: 4-[[(1R,2R,4aS,5R,8aS)-2-(3-carboxypropanoyloxy)-1,4a-dimethyl-6-methylidene-5-[(2E)-2-(2-oxofuran-3-ylidene)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methoxy]-4-oxobutanoic acid. Canonical SMILES: CC12CCC (C (C1CCC (=C)C2C=CC3=CCOC3=O) (C)COC (=O)CCC (=O)O)OC (=O)CCC (=O)O. Density: 1.29g/cm³. Catalog: ACM786593064.
Dehydroanonaine
Dehydroanonaine is a dietary supplement that is used for the treatment of pain. It inhibits the activity of creatine kinase, which is an enzyme that breaks down adenosine triphosphate (ATP) to produce energy. Dehydroanonaine also inhibits acetate extract from fatty acids and has been shown to have an inhibitory effect on tyrosinase, an enzyme involved in the production of melanin. The effective dose for dehydroanonaine is not known. Dehydroanonaine can be used cosmetically by increasing the skin's elasticity and reducing wrinkles and age spots. Group: Other alkaloids. CAS No. 41679-82-7. Molecular formula: C17H13NO2. Mole weight: 263.29 g/mol. Canonical SMILES: C1CNC2= CC3= CC= CC= C3C4= C2C1= CC5= C4OCO5. Catalog: ACM41679827.
Dehydrocorydaline
Dehydrocorydaline (13-Methylpalmatine) is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability?>?90%) using P. falciparum 3D7 strain. Group: Inhibitors. Alternative Names: 13-Methylpalmatine. CAS No. 30045-16-0. Mole weight: 366.4. Purity: 95%+. Catalog: ACM30045160.
Dehydrocorydaline nitrate
Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50?=38 nM), and low cytotoxicity (cell viability?>?90%) using P. falciparum 3D7 strain. Group: Inhibitors. Alternative Names: Hydrocortisonenitrate. CAS No. 13005-09-9. Molecular formula: C22H24N2O7. Mole weight: 428.4. Appearance: Solid. Purity: 95%+. Canonical SMILES: [O-][N+] ([O-])=O. CC1=C (C=CC (OC)=C2OC)C2=C[N+]3=C1C4=CC (OC)=C (OC)C=C4CC3. Catalog: ACM13005099.
Dehydroevodiamine hydrochloride
Other Alkaloids. Alternative Names: 14-Methyl-7,8-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(14H)-one hydrochloride. CAS No. 111664-82-5. Mole weight: 337.80284. Purity: 95%+. Catalog: ACM111664825.
Dehydrojuncusol
Dehydrojuncusol, a potent HCV inhibitor, targets HCV NS5A and is able to inhibit RNA replication of replicons harboring resistance mutations to anti-NS5A direct-acting antivirals. Dehydrojuncusol significantly inhibits HCV infection when added after virus inoculation of HCV genotype 2a (EC50=1.35?μM). Group: Inhibitors. CAS No. 117824-04-1. Molecular formula: C18H16O2. Mole weight: 264.3. Appearance: Powder. Purity: 0.98. IUPACName: 5-ethenyl-1,6-dimethylphenanthrene-2,7-diol. Canonical SMILES: CC1=C (C=CC2=C1C=CC3=CC (=C (C (=C32)C=C)C)O)O. Catalog: ACM117824041.
Dehydro Mefloquine-d5
Dehydro Mefloquine-d5 is the deuterium labeled Dehydro Mefloquine. Group: Isotope-labeled synthetic intermediates. CAS No. 1246819-32-8. Molecular formula: C17H5D5F6N2O. Mole weight: 377.3. Canonical SMILES: FC (F) (C1=CC=CC2=C1N=C (C (F) (F)F)C=C2C (C3=C ([2H])C ([2H])=C ([2H])C ([2H])=N3) ([2H])O)F. Catalog: ACM1246819328.
Dehydroroemerine
Dehydroroemerine is a cyclic peptide that inhibits the enzyme Cox-2, which is involved in the production of inflammatory prostaglandins. This drug has been shown to have anti-inflammatory effects and has been used as a food additive in Japan. Dehydroroemerine has also been reported to have anti-inflammatory properties, which are demonstrated by its ability to inhibit tyrosinase activity. The effective dose of this drug is not yet known; however, it can be administered orally at a concentration of 3 mg/kg body weight. This drug may be used for the treatment of pain models. Group: Other alkaloids. CAS No. 36285-03-7. Molecular formula: C18H15NO2. Mole weight: 277.32 g/mol. Canonical SMILES: CN1CCC2=CC3=C (C4=C2C1=CC5=CC=CC=C54)OCO3. Catalog: ACM36285037.
DEL22379
DEL22379, also known as NPX800, is ERK dimerization inhibitor. DEL-22379 has been reported to inhibit ERK dimerization which was unaffected by drug-resistant mechanism reactivating the ERK signaling. Group: Inhibitors. Alternative Names: DEL22379; DEL-22379; DEL 22379; NPX800; NPX 800; NPX-800. CAS No. 1693734-80-3. Molecular formula: C26H28N4O3. Mole weight: 444.53. Appearance: To be determined. Purity: >98%. IUPACName: N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide. Canonical SMILES: O=C (NC1=CC2=C (NC (/C2=C/C3=CNC4=C3C=C (OC)C=C4)=O)C=C1)CCN5CCCCC5. Catalog: ACM1693734803.
Deleobuvir
Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including faldaprevir. Deleobuvir showed that a triple combination of deleobuvir, faldaprevir, and ribavirin performed well in HCV genotype 1b patients. Efficacy fell below 50%, however, for dual regimens without ribavirin and for genotype 1a patients. In December 2013, deleobuvir was discontinued since recent findings from phase III trials did not suggest sufficient efficacy. Group: Inhibitors. Alternative Names: BI207127; BI-207127; BI 207127; Deleobuvir; BI-207127NA; BI-207127Na. CAS No. 863884-77-9. Molecular formula: C34H33BrN6O3. Mole weight: 653.58. Appearance: Solid powder. Purity: >98%. IUPACName: (E)-3-(2-(1-(2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carboxamido)cyclobutyl)-1-methyl-1H-benzo[d]imidazol-6-yl)acrylic acid. Canonical SMILES: O=C (O)/C=C/C1=CC=C2N=C (C3 (NC (C4=CC5=C (C=C4)C (C6CCCC6)=C (C7=NC=C (Br)C=N7)N5C)=O)CCC3)N (C)C2=C1. Catalog: ACM863884779.
Delgocitinib
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation. Group: Inhibitors. Alternative Names: Delgocitinib; LEO-124249; LEO124249; LEO 124249; JTE-052; JTE 052; JTE052. CAS No. 1263774-59-9. Molecular formula: C16H18N6O. Mole weight: 310.36. Appearance: Solid powder. Purity: >98%. IUPACName: 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile. Canonical SMILES: N#CCC (N1C[C@H] (C)[C@]12CN (C3=C4C (NC=C4)=NC=N3)CC2)=O. Catalog: ACM1263774599.
Delphinidin chloride
Delphinidin chloride, an anthocyanidin, is isolated from berries and red wine. Delphinidin chloride shows endothelium-dependent vasorelaxation. Delphinidin chloride also can modulate JAK/STAT3 and MAPKinase signaling to induce apoptosis in HCT116 cells. Group: Inhibitors. CAS No. 528-53-0. Molecular formula: C15H11ClO7. Mole weight: 338.7. Appearance: Solid. Purity: PRACTICAL. Canonical SMILES: OC1=CC2=C (C=C (C (C3=CC (O)=C (O)C (O)=C3)=[O+]2)O)C (O)=C1. [Cl-]. Catalog: ACM528530.
Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin is the most toxic to insects among the pyrethroid insecticides. It has contact and stomach poisoning effects and is a moderate insecticide. Group: Isotope-labeled environmental contaminants. Alternative Names: Decamethrin-d5. CAS No. 2140301-99-9. Molecular formula: C22H14D5Br2NO3. Mole weight: 510.23. Canonical SMILES: N#C[C@H] (C1=CC (OC2=C ([2H])C ([2H])=C ([2H])C ([2H])=C2[2H])=CC=C1)OC ([C@@H]3[C@@H] (C3 (C)C)/C=C (Br)\Br)=O. Catalog: ACM2140301999.
Demethyleneberberine is a natural drug that inhibits the Cox-2 enzyme, which is involved in the production of prostaglandins. It also inhibits the activity of various receptors and has been shown to decrease the level of dextran sulfate in blood plasma. Demethyleneberberine has been shown to have hypoglycemic effects by improving insulin sensitivity and increasing glucose uptake. This drug has been found to be useful for treating bowel disease, as well as metabolic disorders such as congestive heart failure. Demethyleneberberine is a pro-apoptotic protein that binds to polycyclic aromatic hydrocarbons and coumarin derivatives through its polyphenolic group, which are metabolized by oxidative reactions or reductive reactions. These reactions can be analyzed using liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) methods. Group: Other alkaloids. Alternative Names: 2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium. CAS No. 25459-91-0. Molecular formula: C19H18NO4. Mole weight: 324.35 g/mol. Appearance: Powder. Purity: 0.98. IUPACName: 9,10-Dimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-2,3-diol. Canonical SMILES: COC1=C (C2=C[N+]3=C (C=C2C=C1)C4=CC (=C (C=C4CC3)O)O)OC. Catalog: ACM25459910-1.
DEMETHYLSIMMONDSIN-2'-FERULATE, 4-
Jojoba. Group: Steroids. CAS No. 162290-39-3. Mole weight: 537.51. Appearance: Off white Powder. Catalog: ACM162290393.
Heterocyclic Organic Compound. Alternative Names: demoxytocin;Demossitocina [DCIT];deaminooxytocin;1-(3-Mercaptopropionic acid)oxytocin;Deaminoxytocin;1-[4-(2-amino-2-keto-ethyl)-7-(3-amino-3-keto-propyl)-13-(4-hydroxybenzyl)-3,6,9,12,15-pentaketo-10-sec-butyl-18,19-dithia-2,5,8,11,14-pentazacycloicosan. CAS No. 113-78-0. Molecular formula: C43H65N11O12S2. Mole weight: 992.183. Catalog: ACM113780.
Denudatine
Denudatine is an alkaloid found in the plant families, Aconitum and Veratrum. It is a diterpenoid alkaloid with a structural skeleton that contains an asymmetric carbon atom. Denudatine can be synthesized by reacting acetylacetone with acetic acid and hydrogen chloride gas in a reaction solution. The nmr spectra of denudatine show signals at δ 5.6 (1H), 3.2 (3H), 1.32 (3H) and 1.06 ppm (3H). The chemical reactions of denudatine involve the formation of fatty acids, which are used to produce various substances such as carotenoids, steroids, and vitamin D2. Denudatine has been shown to have receptor binding activity, similar to that of aconitine alkaloids from the genus Aconitum or c19-diterpenoid alkaloids from the genus Ver. Group: Other alkaloids. CAS No. 26166-37-0. Molecular formula: C22H33NO2. Mole weight: 343.5 g/mol. Canonical SMILES: CCN1C[C@@]2 (CCC[C@@]34[C@@H]2C[C@@H] (C31)[C@]56[C@H]4[C@H] ([C@H] (CC5)C (=C)[C@H]6O)O)C. Catalog: ACM26166370.
DeoConcentrate Personal Care
Naturally renewable odor neutralizer that traps & absorbs odors. Contains zinc ricinoleate a zinc salt of ricinoleic acid, derived from zinc and a purified fatty acid from castor seed oil. Is not a masking agent. Liquid form for ease of use. Non-toxic and for safe use. Uses: Odor-neutralizing (deodorant) agent in natural deodorants, sticks, sprays, roll-ons, deodorant agent in cleansers & shampoos. odor control in pet cleansers & shampoos. Group: Sensory modifiers. CAS No. 13040-19-2/137-16-6/102-60-3. Appearance: Clear to slightly hazy, light amber liquid. Catalog: CI-SC-0112.
Deoxy arteether
Heterocyclic Organic Compound. Alternative Names: (2S,3R,3aS,6R,6aS,9S,10aR,10bR)-2-Ethoxydecahydro -3,6,9-trimethyl-0aH-9,10b-Epoxypyrano[4,3,2-jk][2]benzoxepin; Chemal 331; Desoxyarteether A. CAS No. 112297-79-7. Molecular formula: C17H28O4. Mole weight: 296.4. Appearance: White Solid. Purity: 0.96. IUPACName: desoxyarteether. Canonical SMILES: CCOC1C (C2CCC (C3C24C (O1)OC (O4) (CC3)C)C)C. Catalog: ACM112297797.
Deoxybrevianamide e
Deoxybrevianamide E, an indole alkaloid, is a biosynthetic precursor for advanced metabolites isolated from the marine-derived Aspergillus sp. Group: Heterocyclic organic compound. Alternative Names: L-Prolyl-2-(1,1-diMethylallyl)-L-tryptophan anhydride. CAS No. 34610-68-9. Molecular formula: C21H25N3O2. Mole weight: 351.4. Appearance: Oily solid. Purity: 95%+. IUPACName: (3S,8aS)-3-[[2-(2-Methylbut-3-en-2-yl)-1H-indol-3-yl]methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Canonical SMILES: CC (C) (C=C)C1=C (C2=CC=CC=C2N1)CC3C (=O)N4CCCC4C (=O)N3. Catalog: ACM34610689.
Deoxycholic acid (DCA) is a bile acid that plays an important role in the digestion and absorption of dietary fats and fat-soluble vitamins. Uses: It is a natural component of the human body and is produced in the liver from cholesterol. it is also used in laboratory experiments to study the effects of bile acids on cell physiology, metabolism, and gene expression. Group: Heterocyclic organic compound. Alternative Names: Choleic acid. CAS No. 83-44-3. Molecular formula: C24H40O4. Mole weight: 392.58. Appearance: White to off-white solid. Purity: 0.98. IUPACName: (4R)-4-[(3R, 5R, 8R, 9S, 10S, 12S, 13R, 14S, 17R)-3, 12-Dihydroxy-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC (CCC (=O)O)C1CCC2C1 (C (CC3C2CCC4C3 (CCC (C4)O)C)O)C. Density: 1.1±0.1 g/mL. ECNumber: 201-478-5. Catalog: ACM83443-1.
Deoxypodophyllotoxin
Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis. Deoxypodophyllotoxin induces cell autophagy and apoptosis. Deoxypodophyllotoxin evokes increase of intracellular Ca2+ concentrations in DRG neurons. Group: Inhibitors. CAS No. 19186-35-7. Molecular formula: C22H22O7. Mole weight: 398.4. Appearance: Powder. Purity: 0.98. IUPACName: (5R,5aR,8aR)-5-(3,4,5-trimethoxyphenyl)-5a,8,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one. Canonical SMILES: COC1=CC (=CC (=C1OC)OC)C2C3C (CC4=CC5=C (C=C24)OCO5)COC3=O. Catalog: ACM19186357.
Deoxyshikonin
Deoxyshikonin is isolated from Arnebia euchroma with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro. Deoxyshikonin shows significant synergic antimicrobial activity against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA. Group: Inhibitors. CAS No. 43043-74-9. Molecular formula: C16H16O4. Mole weight: 272.3. Appearance: Solid. Purity: 0.9996. Canonical SMILES: O=C1C (CC/C=C (C)/C)=CC (C2=C1C (O)=CC=C2O)=O. Catalog: ACM43043749.
Derrone
Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity. Group: Inhibitors. CAS No. 76166-59-1. Molecular formula: C20H16O5. Mole weight: 336.34. Canonical SMILES: O=C1C2=C (O)C=C3C (C=CC (C) (C)O3)=C2OC=C1C4=CC=C (O)C=C4. Catalog: ACM76166591.
Deruxtecan
Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivative) with a cleavable pepetide linker and a maleimide group. The maleimide group in Deruxtecan can react with antibody to form antibody-drug conguates (ADC) such as Trastuzumab deruxtecan (DS-8201a), which is a HER2-targeting antibody-drug conjugate. DS-8201a significantly suppressed tumor growth in an immunocompetent mouse model with human HER2-expressing CT26.WT (CT26.WThHER2) cells. DS-8201a is currently in clinical trials. Group: Inhibitors. Alternative Names: Deruxtecan, Trastuzumab deruxtecan; DS-8201a; DS8201a; DS 8201a; exatecan derivative; DX-8951 derivative; DX 8951; DX8951. CAS No. 1599440-13-7. Molecular formula: C52H56FN9O13. Mole weight: 1034.07. Appearance: Solid powder. Purity: >98%. IUPACName: Glycinamide, N-[6-(2, 5-dihydro-2, 5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[[2-[[(1S, 9S)-9-ethyl-5-fluoro-2, 3, 9, 10, 13, 15-hexahydro-9-hydroxy-4-methyl-10, 13-dioxo-1H, 12Hbenzo[de]pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]-. Canonical SMILES: CC[C@@]1 (O) C (OCC2=C1C=C3N (C2=O) CC (C3=NC4=CC (F) =C5C) =C6C4=C5CC[C@@H]6NC (COCNC (CNC ([C@@H] (NC (CNC (CNC (CCCCCN7C (C=CC7=O) =O) =O) =O) =O) CC8=CC=CC=C8) =O) =O) =O) =O. Catalog: ACM1599440137.
D-erythro-N,N-Dimethylsphingosine-d6
Labelled D-erythro-N,N-Dimethyl sphingosine. A general modulator of protein kinases. D-erythro-N,N-Dimethylsphingosine is implicated in neuropathic pain. Blocking overproduction of the metabolite N,Ndimethylsphingosine (DMS) in the spinal cord could feasibly represent a therapeutic option for treating neuropathic pain, researchers claim. Group: 2h labeled compounds. CAS No. 171827-65-9. Molecular formula: C20H35D6NO2. Mole weight: 333.58. Catalog: ACM171827659.
Desacetyl diltiazem-d4
Heterocyclic Organic Compound. Alternative Names: (2S-cis)-. CAS No. 112259-40-2. Molecular formula: C20H20D4N2O3S. Mole weight: 376.51. Appearance: ff-White to Pale Yellow Solid. Purity: 0.96. IUPACName: (2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-5-[1,1,2,2-tetradeuterio-2-(dimethylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one. Canonical SMILES: CN (C)CCN1C2=CC=CC=C2SC (C (C1=O)O)C3=CC=C (C=C3)OC. Catalog: ACM112259402.
Desaminotyrosine
Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. Group: Inhibitors. Alternative Names: 3-(4-Hydroxyphenyl)Propionic Acid. CAS No. 501-97-3. Molecular formula: C9H10O3. Mole weight: 166.18. Purity: 0.99. Catalog: ACM501973.
Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity. Group: Inhibitors. Alternative Names: DESETHYL CHLOROQUINE; Deethylchloroquine; Monodeethylchloroquine; N4-(7-Chloro-4-quinolinyl)-N1-ethyl-1, 4-pentanediamine; NSC 13254;WR 29623;4-[[1-Methyl-4-(ethylamino)butyl]amino]-7-chloroquinoline;N'-(7-Chloroquinolin-4-yl)-N-ethyl-1,4-pentanediamine. CAS No. 1476-52-4. Molecular formula: C16H22ClN3. Mole weight: 291.82. Appearance: Tan Solid. Catalog: ACM1476524.
Heterocyclic Organic Compound. Alternative Names: Desmethyl amolodipine;2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl ester;Amlodipine iMpurity J. CAS No. 113994-37-9. Molecular formula: C19H23ClN2O5. Mole weight: 394.85. Density: 1.283. Catalog: ACM113994379.
Desmethylglycitein
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities.Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes. Group: Inhibitors. CAS No. 17817-31-1. Molecular formula: C15H10O5. Mole weight: 270.24. Purity: 0.95. Catalog: ACM17817311.
Desoxo-Narchinol A
Desoxo-narchinol A is an orally active and potent anti-inflammatory agent. Desoxo-narchinol A can be isolated from the roots and rhizomes of Nardostachys jatamansi. Desoxo-narchinol A can be used for septic shock and inflammatory diseases research. Group: Inhibitors. CAS No. 53859-06-6. Molecular formula: C12H16O2. Mole weight: 192.25. Appearance: Powder. Purity: 0.98. IUPACName: (4R,4aS,5R)-4-hydroxy-4a,5-dimethyl-4,5,6,7-tetrahydronaphthalen-1-one. Canonical SMILES: CC1CCC=C2C1(C(C=CC2=O)O)C. Catalog: ACM53859066.