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6-Cl-U
6-Cl-U is the potential biomarker for analysis of chlorine stressed RNA. Synonyms: 6- Chlorouridine. Grades: ≥ 98% by HPLC. CAS No. 2880-89-9. Molecular formula: C9H11ClN2O6. Mole weight: 278.6.
6-cPe-ATP-γ-S
6-cPe-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach). Synonyms: N6- Cyclopentyladenosine- 5'- O- (3- thiotriphosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C15H24N5O12P3S (free acid). Mole weight: 591.4 (free acid).
6-Ethylmercaptopurine, a pharmacological agent specialized for the therapeutic intervention of acute lymphoblastic leukemia (ALL), suppresses DNA biogenesis during cellular division, with consequential fatality of malignant cells. To achieve optimal therapeutic outcomes, 6-Ethylmercaptopurine is frequently combined with other chemotherapy agents in the treatment of ALL. Synonyms: 6-(ethylthio)purine; 6-(ethylthio)-7H-purine; 6-Ethylthiopurine; 6-Ethyl MP; 6-(ethylsulfanyl)-9H-purine; 1H-Purine, 6-(ethylthio)-; 6-(Ethylsulfanyl)-1H-purine. Grades: ≥98% by HPLC. CAS No. 5417-84-5. Molecular formula: C7H8N4S. Mole weight: 180.23.
6-FAM-11-dCTP
6-FAM-11-dCTP, a modified nucleotide employed in molecular biology experimentation, is a highly sought-after material for labeling DNA and RNA. Its employment is particularly useful in fluorescence in situ hybridization (FISH) and DNA sequencing. With use in DNA probe labeling, 6-FAM-11-dCTP is of interest in the detection of genes and mutations linked to diseases including genetic disorders and cancer. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]-2'-deoxycytidine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grades: ≥ 95%.
6-FAM-11-dUTP
6-FAM-11-dUTP is a highly sought-after fluorescent nucleotide derivative in the field of compound research, employed as a distinguished probe. It bestows the ability to proficiently label DNA and RNA fragments within versatile frameworks like DNA sequencing, PCR compound labeling and even in situ hybridization. Consequently, this exceptional compound unfailingly facilitates the visualization and detection of nucleic acids, thereby cementing its worthiness as an indispensable tool in both molecular biology and diagnostics. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]-2'-deoxyuridine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grades: ≥ 95%.
6-FAM-11-UTP
6-FAM-11-UTP is a fluorescent nucleotide analog, possessing the ability to be seamlessly integrated into RNA during the transcription process. This unique characteristic facilitates the visual exploration and identification of RNA molecules, empowering researchers to unravel the intricate workings of these vital biomolecules. Its diverse applications encompass a wide range of studies such as transcriptional investigations, RNA labeling endeavors and the real-time tracking of mRNA research and development. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]- uridine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grades: ≥ 95%.
6-FAM-dC-puromycin
6-FAM-dC-puromycin is a valuable tool in the biomedical industry for studying protein research and development and translation. This compound functions as an RNA mimic, incorporating 6-FAM and dC residues into nascent peptide chains during translation. It enables visualization and tracking of newly synthesized proteins in live cells. 6-FAM-dC-puromycin is particularly useful in researching diseases related to protein research and development and signaling pathways. Grades: ≥ 95% by HPLC. CAS No. 436083-76-0. Molecular formula: C58H65N11O20P2 (free acid). Mole weight: 1298.15 (free acid).
6-Fluo-10-NAD?
6-Fluo-10-NAD? is a fluorescent analogue of β-NAD+ (λexc494 nm, λem517 nm) used as a non-radioactive alternative to radio-labelled β-NAD+ for research on enzymes requiring β-NAD+. Synonyms: β- Nicotinamide- N6- (2- (6- [fluoresceinyl]aminohexanoyl) aminoethyl) adenine dinucleotide, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C50H53N9O21P2 (free acid). Mole weight: 1178 (free acid).
6-Fluorescein dT phosphoramidite
6-Fluorescein dT phosphoramidite can be inserted into the desired sequence as a replacement for a dT residue during oligonucleotides synthesis. Synonyms: Uridine, 5-[3-[[6-[[[3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]amino]hexyl]amino]-3-oxo-1-propen-1-yl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityloxy-5-[N-((3',6'-dipivaloylfluoresceinyl)-aminohexyl)-3-acrylimido]-2'-deoxyuridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Fluorescein-dT Phosphoramidite; Fluorescein dT CEP. Grades: ≥95%. CAS No. 1194507-30-6. Molecular formula: C79H89N6O17P. Mole weight: 1425.56.
6-Fluorescein phosphoramidite
6-Fluorescein phosphoramidite is prepared from 6-carboxyfluorescein derivatives and does not contain 4,4'-dimethoxytrityl (DMT) groups. It can only be added once at the 5'end to terminate the synthesis. Synonyms: FAM Phosphoramidite, 6-Isomer;6-fam phosphoramidite; FAM phosphoramidite, 6-isomer; DyLight FAM-6 CEP; 5'(6)-FAM; 5'-6-Fluorescein phosphoramidite. Grades: ≥90%. CAS No. 204697-37-0. Molecular formula: C46H58N3O10P. Mole weight: 843.94.
6-Fu-ADP
6-Fu-ADP is a precursor of the corresponding radio-labelled triphosphate that can be used for studies on kinase-substrate relationships (chemical genetics approach). Grades: ≥ 95% by HPLC. Molecular formula: C15H19N5O11P2 (free acid). Mole weight: 507.3 (free acid).
6-Fu-ATP
6-Fu-ATP is an analogue of ATP used to specifically interact with modified receptor proteins (chemical genetics approach). Synonyms: N6- Furfuryladenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1450894-16-2. Molecular formula: C15H20N5O14P3 (free acid). Mole weight: 587.3 (free acid).
6-Fu-ATP-γ-S
6-Fu-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach). Synonyms: N6- Furfuryladenosine- 5'- O- (3- thiotriphosphate), sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1400539-83-4. Molecular formula: C15H20N5O13P3S (free acid). Mole weight: 603.3 (free acid).
6-(Furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is a highly efficacious antiviral compound, finding significant utility within the biomedical sphere for research of viral infections. By impeding viral replication and dissemination, it attenuates the deleterious manifestations associated with these infections. Synonyms: 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine; (2R,3S,4S,5R)-4-Fluoro-2-(6-(furan-2-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol; 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furanyl)-. Grades: ≥95%. CAS No. 1612191-89-5. Molecular formula: C14H13FN4O4. Mole weight: 320.28.
6-(Furan-2-yl)purine-beta-D-riboside
6-(Furan-2-yl)purine-beta-D-riboside is an indispensable compound compound, exhibiting inhibitory potential in the research of diverse ailments such as leukemia and cancer. Synonyms: 9-(β-D-Ribofuranosyl)-6-(furan-2-yl)purine; 9-(beta-D-Ribofuranosyl)-6-(2-furyl)-9H-purine; (2R,3R,4S,5R)-2-[6-(2-furyl)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 352025-81-1. Molecular formula: C14H14N4O5. Mole weight: 318.28.
6-HT-cGMP
6-HT-cGMP, a cyclic guanosine monophosphate (cGMP) analog, has been subject to extensive research as a prospective therapy for cardiovascular ailments. With vasoconstriction being a leading cause of such diseases, extensive studies have shown that 6-HT-cGMP act as a vasodilator. Animal models have indicated that it can increase coronary blood flow, giving it potential clinical implications. Furthermore, 6-HT-cGMP is promising in the treatment of erectile dysfunction. A comprehensive understanding of its properties and mechanisms is imperative as it shows great potential in treating these prevalent conditions. Synonyms: 6- Hexylthioguanosine- 3', 5'- cyclic monophosphate. Molecular formula: C16H23N5O6PS · Na. Mole weight: 467.4.
6-Iodo-uridine
6-Iodo-uridine is a nucleoside analogue that has potential antiviral activity against herpes simplex virus-1. It has also been investigated for use in cancer treatment due to its ability to induce differentiation in tumor cells. Synonyms: 6-iodouridine; uridine, 6-iodo-. CAS No. 105967-11-1. Molecular formula: C9H11IN2O6. Mole weight: 370.10.
6-MBC-cAMP
6-MBC-cAMP is a selective activator of protein kinase A, the cAMP agonist, which has a preference for the A site of cAK II. It can be active to type II in combination of Sp-5,6-DCl-cBIMPS. Synonyms: 6-MBC-CAMP SODIUM SALT; 84433-46-5; sodium; N-[[9-(7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)purin-6-yl]carbamoyl]-2,2-dimethylpropanamide; 6-MBC-cAMP. Grades: ≥ 98% by HPLC. CAS No. 84433-46-5. Molecular formula: C15H20N6O7P · Na. Mole weight: 450.3.
6-Me-5'-AMP
6-Me-5'-AMP is an adenosine monophosphate analog, exhibiting remarkable versatility in the research of diverses as cancer, inflammation and cardiovascular diseases. This groundbreaking compound intricately influences specific biochemical pathways, thereby serving as a pivotal asset in the domains of drug discovery, development and screening. Grades: ≥ 97% by HPLC. CAS No. 81921-35-9. Molecular formula: C11H16N5O7P (free acid). Mole weight: 361.3 (free acid).
6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine
6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine, a remarkable antiviral compound extensively utilized in the biomedical field, demonstrates exceptional effectiveness against an array of diverse DNA and RNA viruses, encompassing hepatitis B and C, HIV, and herpes simplex viruses. By obstructing viral DNA/RNA synthesis and viral polymerase activity, this compound exerts a potent inhibitory effect on viral replication. Synonyms: 6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine; 2'-Deoxy-6-thioinosine; NSC 90557; 6-Mercaptopurine deoxyriboside; NSC 409366; 6-Mercaptopurine-2'-deoxyribonucleoside; 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thiol; 6-thio-2'-deoxyinosine; 6-Thiopurine-2'-deoxyriboside. Grades: ≥95%. CAS No. 2239-64-7. Molecular formula: C10H12N4O3S. Mole weight: 268.29.
6-Mercaptopurine Riboside
A substrate for adenosine deaminase. Uses: Antimetabolites, antineoplastic. Synonyms: 6-Thioinosine; Ribosyl-6-thiopurine; 6-Thio-9-β-D-ribofuranoside6-Thioinosine. Grades: 90%. CAS No. 574-25-4. Molecular formula: C10H12N4O4S. Mole weight: 284.29.
6-Mercaptopurine-riboside-5'-diphosphate
6-Mercaptopurine-riboside-5'-diphosphate is a metabolite of mercaptopurine, a thiopurine used as an immunosuppressive drug. Synonyms: 6-Thio-inosine-5'-diphosphate; 6-Mercaptopurine-riboside-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 805-63-0. Molecular formula: C10H14N4O10P2S (free acid). Mole weight: 444.25 (free acid).
6-Mercaptopurine-riboside-5'-monophosphate
6-Mercaptopurine-riboside-5'-monophosphate is a metabolite of 6-Mercaptopurine. Synonyms: 6-Thio-Inosine-5'-monophosphate; 6-Mercaptopurine-riboside-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 53-83-8. Molecular formula: C10H13N4O7PS (free acid). Mole weight: 364.26 (free acid).
6-Mercaptopurine-riboside-5'-triphosphate
6-Mercaptopurine-riboside-5'-triphosphate is a metabolite of mercaptopurine, a thiopurine used as an immunosuppressive drug. Synonyms: 6-Thio-Inosine-5'-triphosphate; 6-Mercaptopurine-riboside-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 27652-34-2. Molecular formula: C10H15N4O13P3S (free acid). Mole weight: 524.22 (free acid).
6-Methoxy-9-(2-C-methyl-beta-D-ribofuranosyl)purine is a potent antiviral compound used in the research of viral infections, particularly those caused by herpes viruses. It exhibits a high selectivity index and low toxicity towards host cells, making it an effective option for suppressing viral replication. This nucleoside analogue inhibits the viral DNA polymerase, thus preventing viral DNA research and development and subsequent viral replication. Synonyms: (2R,3R,4R,5R)-5-(hydroxymethyl)-2-(6-methoxy-9H-purin-9-yl)-3-methyltetrahydrofuran-3,4-diol; 2'-C-Methyl-6-O-methylinosine; Inosine, 2'-C-methyl-6-O-methyl-; 9H-Purine, 6-methoxy-9-(2-C-methyl-β-D-ribofuranosyl)-. Grades: ≥95%. CAS No. 565450-78-4. Molecular formula: C12H16N4O5. Mole weight: 296.28.
6-Methoxy-9-(3-deoxy-3-fluoro-b-D-ribofuranosyl)-9H-purine, an efficacious antiviral agent, is extensively employed to combat specific viral infections. By impeding viral replication and curtailing the spread of the infection, it manifests exceptional therapeutic potential. Synonyms: 6-Methoxypurine-9-β-D-(3'-deoxy-3'-fluoro)riboside. Grades: ≥95%. CAS No. 2072145-35-6. Molecular formula: C11H13FN4O4. Mole weight: 284.24.
6-Methoxy-9-(β-D-5(R)-methylribofuranosyl)-9H-purine is a profound and influential antiviral compound, finding application in research of diverse viral infections encompassing herpes simplex virus, varicella-zoster virus and Epstein-Barr virus. By focusing on viral enzymes, it suppresses viral replication. Synonyms: Methoxypurine-9-beta-D-5'(R)-methylriboside; 6-O-Methyl-5'(R)-methylinosine. Grades: ≥95%. Molecular formula: C12H16N4O5. Mole weight: 296.28.
6-Methyl-9-(beta-D-ribofuranosyl)-9H-purine
It is a natural antibiotic, antifungal and antiviral agent. Synonyms: 6-D-MPR; 9H-Purine, 6-methyl-9-b-D-ribofuranosyl-; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol; 6-Methylpurine-beta-D-ribonucleoside; 6-Methyl-9-β-D-ribofuranosylpurine; NSC 101619; 6-Methylpurine ribonucleoside. Grades: ≥95%. CAS No. 14675-48-0. Molecular formula: C11H14N4O4. Mole weight: 266.25.
6-Methyl-9-(beta-D-xylofuranosyl)purine
6-Methyl-9-(beta-D-xylofuranosyl)purine, coined as a paradigm-shifting biomedical compound, unveiling its prodigious potentiality in the research of viral afflictions like the influenza and the herpes. Synonyms: 6-Methyl-9-(β-D-xylofuranosyl)-9H-purine; NSC 102254; 9H-Purine, 6-methyl-9-β-D-xylofuranosyl-; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 16006-65-8. Molecular formula: C11H14N4O4. Mole weight: 266.25.
6-Methylaminopurine arabinoside
6-Methylaminopurine arabinoside, a nucleoside analogue lauded for its capacity in effectively treating viral infections, whether sly herpes simplex virus (HSV) or varicella-zoster virus (VZV) infections, reaps its rewards by preventing viral DNA synthesis and replication. Its impacts are significant in thwarting a multitude of diseases. Synonyms: 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-N-methyl-; Ara-map; 9-β-D-arabinofuranosyl-N-methyladenine; NSC 409168; 9-beta-D-Arabinofuranosyl-N-methyl-9H-purin-6-amine; 9H-Purin-6-amine, 9-β-D-arabinofuranosyl-N-methyl-. Grades: ≥95% by HPLC. CAS No. 60209-41-8. Molecular formula: C11H15N5O4. Mole weight: 281.27.
6-Methylpseudouridine
6-Methylpseudouridine is a powerful and discerning antiviral compound, boasting remarkable efficacy in the research of notorious RNA viruses like the Zika virus and hepatitis C. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 6-methyl-5-β-D-ribofuranosyl-; 6-Methyl-5-beta-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 1613530-10-1. Molecular formula: C10H14N2O6. Mole weight: 258.23.
6-Methylpurine-b-D-(3-azido-3-deoxy)riboside
6-Methylpurine-b-D-(3-azido-3-deoxy)riboside is a profoundly efficacious antiviral compound, displaying its prowess by curbing the replication of RNA viruses via its targeted interaction with the viral RNA-dependent RNA polymerase. Synonyms: 6-Methylpurine-β-D-(3-azido-3-deoxy)riboside. Grades: ≥95%. CAS No. 2095417-25-5. Molecular formula: C11H13N7O3. Mole weight: 291.27.
6-Methylthio-GDP
6-Methylthio-GDP, an intriguing nucleotide analog, is well-known for its application in synthesizing RNA and DNA. Capable of impeding RNA polymerase activity, this compound has been explored as a promising candidate for anti-cancer drugs. Furthermore, its antiviral activity against selective RNA viruses has been demonstrated. These properties render it an essential compound in biomedicine research. Synonyms: 6-Methylthioguanosine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H17N5O10P2S (free acid). Mole weight: 473.29 (free acid).
6-Methylthio-GMP
6-Methylthio-GMP, a highly potent nucleotide analog, exhibits remarkable efficacy against diverse viral infections and several cancers. This promising molecule significantly interferes with DNA synthesis, thereby repressing tumor growth and inhibiting viral replication. Moreover, cutting-edge research indicates its potential for treating inflammation. Synonyms: 6-Methylthioguanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H16N5O7PS (free acid). Mole weight: 393.31 (free acid).
6-Methylthio-GTP
6-Methylthio-GTP, a pivotal determinant in the bio-mechanisms modulating GTPase activity, renders itself an irreplaceable asset for biomedical studies analyzing post-translational modifications. By examining its interactions with effectors proteins in the context of diseases spanning from cancer to neurodegenerative disorders, this compound furthers our understanding of the intricate workings of the human body and aids in the fight against various ailments. Synonyms: 6-Methylthioguanosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 70318-62-6. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.27 (free acid).
6-Methylthio-guanosine
6-Methylthio-guanosine, a petite molecule, offers a vantage point for investigating the intricate interplay between post-transcriptional modification and gene expression. Its structural resemblance to S-adenosylmethionine, along with a demonstrated impact on mRNA transcript stabilization and translation regulation, hold immense value for scientific investigations. Furthermore, its potential therapeutic applications in treating viral infections and cancer open up new avenues of exploration for the scientific community. Grades: ≥ 98%. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
6-Methylthio-IDP
6-Methylthio-IDP is a pharmacologically powerful compound, exhibiting robust antiviral properties against a diverse range of viral pathogens, such as HIV/AIDS. Its mechanism of action involves impeding the viral replication cycle, thereby circumventing compound-resistant strains. Synonyms: 6-Methylthioinosine-5'-diphosphate, Sodium salt; 6-Methylmercapto-9-(β-D-ribofuranosyl)purine-5'-diphosphate. Grades: ≥ 95% by HPLC. Molecular formula: C11H16N4O10P2S (free acid). Mole weight: 458.27 (free acid).
6-Methylthio-IMP
6-Methylthio-IMP is an antimetabolite that inhibits de novo purine synthesis. It exhibits an antitumor effect in vivo. Synonyms: 6-Methylthioinosine-5'-monophosphate, Triethylammonium salt; 6-Methylmercapto-9-(β-D-ribofuranosyl)purine-5'-monophosphate. Grades: ≥ 95% by HPLC. CAS No. 7021-52-5. Molecular formula: C11H15N4O7PS (free acid). Mole weight: 378.29 (free acid).
6-Methylthio-inosine
6-Methylthio-inosine, a compound utilized in the biomedical sphere to heal cardiac ailments, has the unique ability to restrain enzymes implicated in purine metabolism. Its medicinal properties do not end there; research has also uncovered its potential in battling malignant tumors, such as leukemia and breast cancer. Grades: ≥ 98%. Molecular formula: C11H14N4O4S. Mole weight: 298.31.
6-Methylthio-ITP
6-Methylthio-ITP, a small molecule with potential biomedical significance, is utilized in the scientific investigation of purinergic signaling with regard to platelet activation and aggregation. Furthermore, its aptness extends to the comprehensive exploration of purinergic receptors and their involvement in diverse ailments, namely but not limited to cardiovascular disease and cancer. Synonyms: 6-Methylthioinosine-5'-triphosphate, Sodium salt; 6-Methylmercapto-9-(β-D-ribofuranosyl)purine-5'-triphosphate. Grades: ≥ 95% by HPLC. CAS No. 51464-82-5. Molecular formula: C11H17N4O13P3S (free acid). Mole weight: 538.25 (free acid).
6-Methyluridine
6-Methyluridine is an indispensable nucleoside analog, spearheading innovation in antiviral compound research and development. Synonyms: 6-Methyl-D-uridine; 4-p-aminobenzenesulphonamidopyridine; 4-amino-N-pyridin-4-yl-benzenesulfonamide; N1-6-methyluridine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione; NSC 112513. Grades: ≥95%. CAS No. 16710-13-7. Molecular formula: C10H14N2O6. Mole weight: 258.23.
6-N-Acyl-6-N-methyl-2'-deoxyadenosine
6-N-Acyl-6-N-methyl-2'-deoxyadenosine, a potential anti-cancer drug, has exhibited the ability to impede the growth of multiple cancer cell types inclusive of breast, lung, and colon cancer cells. The mechanism of action is believed to entail the inhibition of DNA synthesis and the induction of apoptosis. Further research is currently underway to investigate its viability as a cancer treatment. Grades: ≥ 95%. CAS No. 1377950-60-1. Molecular formula: C13H17N5O4. Mole weight: 307.31.
6'-NH2-Ado
6'-NH2-Ado is an inhibitor of adenosine kinase. Synonyms: 6'- Amino- 6'- deoxyadenosine. Grades: ≥ 96% by HPLC. CAS No. 14366-44-7. Molecular formula: C10H14N6O3. Mole weight: 266.3 (free base).
6-O-[2-(4-Nitrophenyl)ethyl]-2-(2-furanylmethylamino)-2'-deoxyinosine, an immensely powerful nucleoside analogue, stands as a quintessential substance extensively employed within the realm of biomedical research. With its profound efficacy in combating specific viral infections, it emerges as an exemplary specimen, streamlining the analysis of viral replication and paving the way for unprecedented therapeutic innovations. Grades: ≥95%. Molecular formula: C23H24N6O7. Mole weight: 496.47.
6-O-Ethylguanosine
6-O-Ethylguanosine is a guanosine derivative and have been studied as potential covalent carcinogenic lesions in DNA. Synonyms: O6-Ethylguanosine. CAS No. 39708-01-5. Molecular formula: C12H17N5O5. Mole weight: 311.29.
6-O-Methylinosine
6-O-Methylinosine is a groundbreaking biomedical compound, thwarting the relentless progression of malignant tumors by effectively obstructing the relentless propagation of cancerous cells. Synonyms: 6-Methoxypurine-9-beta-D-riboside; 6-Methoxy-9-(β-D-ribofuranosyl)-9H-purine; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methoxy-9H-purin-9-yl)tetrahydrofuran-3,4-diol; 6-Methoxypurine riboside; 6-Deamino-6-methoxyadenosine. Grades: ≥95%. CAS No. 5746-29-2. Molecular formula: C11H14N4O5. Mole weight: 282.25.
6-Phe-ATP-γ-S
6-Phe-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach). Synonyms: N6- Phenyladenosine- 5'- O- (3- thiotriphosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H20N5O12P3S (free acid). Mole weight: 599.4 (free acid).
6-Phe-cAMP
6-Phe-cAMP is a selective stimulator of protein kinase A preferring site A of both isozymes. Synonyms: N(6)-phenyl-cAMP; N6-phenyl-cAMP; 34051-30-4; Adenosine,N-phenyl-,cyclic 3',5'-(hydrogen phosphate); sodium; (4aR,6R,7R,7aS)-6-(6-anilinopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol. Grades: ≥ 98% by HPLC. CAS No. 34051-30-4. Molecular formula: C16H15N5O6P · Na. Mole weight: 427.3.
6-PhEt-dATP
6-PhEt-dATP is a potentiates activity of disease-associated CFTR channel mutants. Grades: ≥ 95% by HPLC. CAS No. 1239610-11-7. Molecular formula: C18H24N5O12P3 (free acid). Mole weight: 595.3 (free acid).
6-SH-PuR
6-SH-PuR, a fascinating chemical compound that is utilized in the examination of biological systems. The compound has been verified to lower the creation of protein conglomerations and diminish oxidative stress, therefore, transforming into a promising therapeutic agent for treating neurodegenerative illnesses such as Parkinson's and Alzheimer's. Further studies have even looked into its intriguing potential as an anticancer means. CAS No. 674-26-4. Molecular formula: C10H12N4O4S. Mole weight: 284.3.
6-SMe-PuR
6-SMe-PuR, a highly favored and discriminating agonist for the adenosine A3 receptor, has been instrumental in paving the way for biomedical exploration into the multifaceted roles of the A3 receptor in various ailments ranging from tumorous growth to neuro-degenerative complications. Such valued research apparatus not only opens doors for better comprehension of said pathologies, but also augment opportunities for creation of fresh drug prospects emphasizing the adenosine A3 receptor. Synonyms: 6-S-Methyl-6-thio-inosine; 6-Methylmercaptopurine Riboside; 6-Methylthiopurine Riboside; 6-MMPR; 6-Methyl MP riboside; 6-Methylthioinosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; 6-(Methylthio)-9-beta-D-ribofuranosyl-9H-purine. Grades: ≥95%. CAS No. 342-69-8. Molecular formula: C11H14N4O4S. Mole weight: 298.32.
6-Tetrachloro-Fluorescein Phosphoramidite
6-Tetrachloro-Fluorescein Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Synonyms: DyLight TET CEP; MFCD01940926; ZINC150664310. Grades: ≥95%. CAS No. 877049-90-6. Molecular formula: C46H54N3O10Cl4P. Mole weight: 981.72.
6-Thio-2'-deoxyguanosine-5'-Triphosphate
6-Thio-2'-deoxyguanosine-5'-Triphosphate, a nucleoside analog, presents a diverse range of cellular disease treatment applications. This product's specialty is its sulfur atom which facilitates thorough study of DNA repair enzymes and mechanisms, as well as adduct formation caused by an array of chemical agents. Consequently, this substrate routinely features in polymerase chain reactions to synthesize DNA fragments bearing specific mutationsa remarkable feat that cements its significance in scientific research. Synonyms: 6-Thio-dGTP; 2-Amino-9-{2-Deoxy-5-O-[ (R) -Hydroxy{[ (R) -Hydroxy (Phosphonooxy) phosphoryl]oxy}phosphoryl]-Beta-D-Erythro-Pentofuranosyl}-1, 9-Dihydro-6h-Purine-6-Thione. Grades: ≥ 95% by HPLC. CAS No. 17660-38-7. Molecular formula: C10H16N5O12P3S (free acid). Mole weight: 523.25 (free acid).
6-Thio-9-(b-D-arabinofuranosyl)purine
6-Thio-9-(b-D-arabinofuranosyl)purine, also known as 6-TG, is a prominent biomedicine applied extensively for treating a wide range of ailments. Renowned for its superior antimetabolite properties, this compound effectively hampers DNA synthesis, impeding the uncontrolled growth of malignant cells. Uses: Antineoplastic agents. Synonyms: 6-Mercapto-9-(b-D-arabinofuranosyl)purine. CAS No. 892-49-9. Molecular formula: C10H12N4O4S. Mole weight: 284.29.
6-Thio-dG
6-thio-dG is a nucleoside analog and telomerase substrate. Uses: Studies suggest that beta-tgdr is a latent form of tg. since resistance to antileukemic agent 6-thioguanine inevitably develops in animal tumors, this new agent beta-tgdr is of potential clinical use. Synonyms: 6-Thio-2'-Deoxyguanosine; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine; 2'-Deoxythioguanosine; 2'-Desoxy-6-thioguanosine; NSC 71261; TGdR; Thioguanine Deoxyriboside; β-Thioguanine Deoxyriboside. Grades: ≥97% by HPLC. CAS No. 789-61-7. Molecular formula: C10H13N5O3S. Mole weight: 283.31.
6-Thio-GMP
6-Thio-GMP, a bioactive compound employed for biomedical research, demonstrates inhibitory effects on numerous tumors, rendering it a prospective therapeutic intervention for leukemia and lymphoma. Moreover, it displays antiviral capability as validated by its potency to inhibit replication of viruses such as Ebola virus. Synonyms: 6-Thio-guanosine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 15867-02-4. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid).
6-Thio-GpCp
6-Thio-GpCp, a compound that exhibits inhibitory activities against viral replication as well as DNA synthesis in cancerous cells, is a compound with immense potential in the fight against viral infections and specific types of cancer. It has demonstrated compelling data in preclinical trials and is currently under development for further clinical investigation. Synonyms: (6-Thio-GMPCP); 6-Thio-guanosine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H17N5O9P2S (free acid). Mole weight: 457.29 (free acid).
6-Thio-GppCp
6-Thio-GppCp, a nucleotide analog widely used in molecular and cell biology research, functions as a potent competitive inhibitor of guanine nucleotides. With its ability to disrupt various signaling pathways, this compound is a crucial tool in studying cancer and infectious diseases. Beyond its impact on cell proliferation, it is also known to trigger apoptosis, thereby offering invaluable insight into disease progression. Synonyms: (6-Thio-GMPPCP); 6-Thio-guanosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H18N5O12P3S (free acid). Mole weight: 537.27 (free acid).
6-Thio-GppNHp
6-Thio-GppNHp - A Biochemical Product with Revolutionary potential! This product is indispensable in biosciences research and allows scientists to deeply probe the intricacies of G protein signaling pathways. An entirely non-hydrolyzable analog of GTP, 6-Thio-GppNHp has opened up a vast realm of investigations into the effects of G protein activation, intracellular signal transduction, and some of the most enigmatic diseases plaguing humankind - cardiac arrhythmias, immune response, and cancer. Join the path-breaking efforts today with your 6-Thio-GppNHp! Synonyms: (6-Thio-GMPPNP); 6-Thio-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N6O12P3S (free acid). Mole weight: 538.25 (free acid).
6-Thio-guanosine
6-Thio-guanosine is an esteemed pharmaceutical compound, unveiling its remarkable prowess in research of pervasive viral infections. It ingeniously inhibits viral replication and the intricate enhancement of nucleic acids within afflicted cell. Grades: ≥ 98%. Molecular formula: C10H13N5O4S. Mole weight: 299.3.
6-Thioguanosine-5'-O-monophosphate sodium salt
6-Thioguanosine-5'-O-monophosphate sodium salt is an indispensable element in biomedical research, demonstrating its significance as a precursor in the development of anti-viral and anti-neoplastic medications. Its prowess lies in accurately and efficiently targeting viral replication and cancer cell proliferation. Synonyms: Sodium ((2R,3S,4R,5R)-5-(2-amino-6-thioxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate; disodium; [(2R,3S,4R,5R)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate. Grades: ≥ 98% (HPLC). CAS No. 74686-78-5. Molecular formula: C10H13N5O7PS·xNa. Mole weight: 378.28 (free acid).
7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine, an intricate compound of paramount significance, finds extensive application in the biomedical sector for combating diverse viral infections. It unveils remarkable inhibitory potential against particular viruses through its precise engagement with vital viral enzymes or proteins, thereby impeding the replication and dissemination of the pathogens. Synonyms: (2R,3R,4R,5R)-2-(2-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol;443642-48-6;SCHEMBL731577;ZHRLTTOGZNAIAQ-FWSPBBIJSA-N;ZINC34003523;NU000308. Grades: 95%. CAS No. 443642-48-6. Molecular formula: C12H16N4O4. Mole weight: 280.28.
7-[3,5-Bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl-beta-D-ribofuranosyl]-4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine, a highly intricate and dynamic compound, exhibits remarkable antiviral properties. This remarkable pharmaceutical marvel has been harnessed specifically for combating viral infections, offering a powerful mechanism of action that disrupts viral replication by precisely targeting crucial enzymes involved in viral DNA synthesis. Synonyms: (3R,4R,5R)-2-(4-chloro-5-methylpyrrolo[2,3-d]pyrimidin-7-yl)-4-[(2,4-dichlorophenyl)methoxy]-5-[(2,4-dichlorophenyl)methoxymethyl]-3-methyloxolan-3-ol;NU008035;443642-54-4. Grades: 95%. CAS No. 443642-54-4. Molecular formula: C27H24Cl5N3O4. Mole weight: 631.76.
7,8-Dihydro-8-oxo-7-propargylguanosine
7,8-Dihydro-8-oxo-7-propargylguanosine, identified as a robust antiviral agent, finds extensive application within the biomedical sphere for combating RNA virus-induced infections. By impeding the synthesis of viral nucleic acid, its mechanism of action contributes to the inhibition of viral replication. Thus, notable efficacy is observed against conditions including hepatitis C and respiratory syncytial virus. Grades: ≥95%. Molecular formula: C13H15N5O6. Mole weight: 337.29.
7-Allyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine is a remarkably potent antiviral compound extensively used for studying a myriad of viral infections, with a particular emphasis on the herpes simplex viruses (HSV) as well as the varicella-zoster virus (VZV). Empowered by its ability to effectively impede viral DNA enhancement through strategic targeting of viral DNA polymerase. Synonyms: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-prop-2-enyl-1H-purine-6,8-dione; 7-Allyl-2-amino-9-(β-D-arabinofuranosyl)-7,9-dihydro-3H-purine-6,8-dione. Grades: ≥95%. CAS No. 2389988-25-2. Molecular formula: C13H17N5O6. Mole weight: 339.30.
7-Cyano-7-deaza-2'-deoxyadenosine
7-Cyano-7-deaza-2'-deoxyadenosine, a promising antineoplastic agent, is employed to combat solid tumors by thwarting DNA synthesis in neoplastic cells. As per various reports, this compound has displayed efficacy against several cancer forms, such as prostate cancer, colon cancer, and lung malignancies. Further, it has been seen to yield better outcomes when combined with other chemotherapy drugs. Synonyms: 4-Amino-5-cyano-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine. Grades: 95%. CAS No. 15676-19-4. Molecular formula: C12H13N5O3. Mole weight: 275.26.
7-Cyano-7-deaza-2'-deoxyguanosine
7-Cyano-7-deaza-2'-deoxyguanosine is a potent antiviral nucleoside analogue commonly used in the biomedical industry for the treatment of viral infections. It demonstrates promising activity against various viruses, including hepatitis B and C. It functions by inhibiting viral replication through targeting viral polymerase enzymes. Synonyms: 2-Amino-7-(2-deoxy-b-D-ribofuranosyl)-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one; 2'-Deoxytoyocamycin; 2-Amino-7-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile. Grades: ≥95%. CAS No. 199859-58-0. Molecular formula: C12H13N5O4. Mole weight: 291.26.
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine is a remarkable and influential antiviral agent of immense scientific significance. This potent reagent, revered for its remarkable efficacy, is indispensable in combatting viral infections caused by the notorious herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its mechanism of action revolves around the inhibition of viral DNA synthesis, serving as a formidable barricade against viral replication. Synonyms: 2-amino-7-(cyclopropylmethyl)-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-6,8-dione. Grades: ≥95%. CAS No. 2389988-23-0. Molecular formula: C14H19N5O6. Mole weight: 353.33.