BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 2'-Chloro-N6-benzyladenosine | 2'-Chloro-N6-benzyladenosine, a diminutive molecule utilized in the biomedical sector, presents ample potential in treating numerous ailments, encompassing cancer, inflammation, and cardiovascular disorders via the regulation of cellular processes. Its mechanism of action happens by counteracting specific enzymes while stimulating others. This compound proves invaluable in gathering insights regarding disease mechanisms and treating conditions in research settings. Synonyms: (2R,3R,4S,5R)-2-[6-(benzylamino)-2-chloropurin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol. Grades: ≥95%. CAS No. 23558-62-5. Molecular formula: C17H18ClN5O4. Mole weight: 391.81. |  |
| 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine | 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is a revolutionary adenosine analog, boasting an impressive range of therapeutic capabilities. Employed in the treatment of blood, breast, and lung cancers, this powerful compound exerts its anticancer effect through the inhibition of DNA synthesis and induction of apoptosis in cancer cells. Widely regarded as an invaluable tool in the scientific community, this product is commonly implemented in research studies aimed at uncovering the elusive mechanisms of action of other promising anticancer drugs. Synonyms: 9H-Purin-6-amine, 2-chloro-N-cyclopentyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-; 2-Chloro-N6-cyclopentyl-2'-fluoro-β-D-arabinoadenosine; (2R,3R,4S,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-4-fluoro-2-(hydroxymethyl)oxolan-3-ol. Grades: ≥95%. CAS No. 2216764-33-7. Molecular formula: C15H19ClFN5O3. Mole weight: 371.79. | |
| 2-Chloro-N6-cyclopentyl 2'-deoxy-adenosine | 2-Chloro-N6-cyclopentyl 2'-deoxy-adenosine, a chemical compound used in the biomedical industry to research treatments for various diseases, including cancers and viral infections such as HIV and hepatitis B, has captivated the interest of researchers worldwide. However, its therapeutic potential extends far beyond infectious diseases- studies suggest that it may serve as a potent agent for treating neurodegenerative disorders such as Parkinson's and Alzheimer's. Synonyms: (2R,3S,5R)-5-(2-Chloro-6-cyclopentylamino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol; AAG125; (2R,3S,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol; 2-Chloro-N-cyclopentyl-2'-deoxyadenosine; 2-chloro-6-(cyclohexylamino)-9-(2'-deoxy-β-D-erythro-pentofuranosyl)-9H-purine. Grades: ≥95%. CAS No. 215108-39-7. Molecular formula: C15H20ClN5O3. Mole weight: 353.80. | |
| 2-Chloro-N6-cyclopentyladenosine | It is a selective adenosine receptor agonist and inhibits angiotensin II-induced cardiomyocyte hypertrophy through the calcineurin signaling pathway. Synonyms: CCPA; 2-Chloro-N-cyclopentyl-adenosine; (2R,3R,4S,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-chloro-N-cyclopentyl-9-pentofuranosyl-9H-purin-6-amine. Grades: ≥95% by HPLC. CAS No. 37739-05-2. Molecular formula: C15H20ClN5O4. Mole weight: 369.80. | |
| 2-Chloro-N6-iso-pentenyladenosine | 2-Chloro-N6-iso-pentenyladenosine is a remarkable adenosine receptor agonist, finding tremendous significance in the realm of biomedical research. By unlocking the intricate adenosine signaling pathways and deciphering its profound impact on cell proliferation, apoptosis, and immune response, this compound opens up a realm of uncharted possibilities. Thorough research and in-depth analysis shall unravel the enigmatic biochemical properties and mechanisms of action inherent to this intriguing compound. Synonyms: (2R,3R,4S,5R)-2-[2-chloro-6-(3-methylbut-2-enylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol; 2-Chloro-N-(3-methyl-2-buten-1-yl)adenosine; Adenosine, 2-chloro-N-(3-methyl-2-buten-1-yl)-. Grades: ≥95%. Molecular formula: C15H20ClN5O4. Mole weight: 369.80. | |
| 2-Chloro-N6-isopropyladenosine | 2-Chloro-N6-isopropyladenosine, a chemical compound employed in biomedical research, holds the unique ability to selectively augment cAMP levels. Coupled with its capacity to suppress the growth and proliferation of tumor cells, it envisions a promising therapeutic intervention strategy for specific types of cancer. Furthermore, research has unveiled its role in mitigating inflammation and toxicity in the liver. Grades: ≥95%. CAS No. 23541-30-2. Molecular formula: C13H18ClN5O4. Mole weight: 343.77. | |
| 2-Chloro-N6-methyladenosine | 2-Chloro-N6-methyladenosine, a powerful molecule utilized within the biomedicine sector, boasts an array of benefits that distinguish it as a top organic compound option for exploring cancer treatment methods. Research has revealed that this chemical entity exudes strong RNA methylation inhibiting qualities which generate a drastic reduction in cancer cell proliferation and tumor growth, particularly relevant in the case of breast and lung cancers. Additionally, due to its epigenetic regulatory nature centering around gene expression and RNA processing, it serves as an invaluable tool fueling researchers' investigations into these crucial realms. Synonyms: (2R,3R,4S,5R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenosine, 2-chloro-N-methyl-; 2-Chloro-N-methyladenosine. Grades: ≥95%. CAS No. 13406-50-3. Molecular formula: C11H14ClN5O4. Mole weight: 315.71. | |
| 2-Chloro-N6,N6-dimethyladenosine | 2-Chloro-N6,N6-dimethyladenosine, a modified nucleotide commonly employed in RNA splicing and processing analyses, has displayed promising results in elevating the effectiveness of chemotherapy drugs. Additionally, its utility in mitigating a plethora of critical ailments encompassing viral infections and malignant neoplasms renders it a viable therapeutic research candidate. Synonyms: (2R,3R,4S,5R)-2-[2-chloro-6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol; N,N-Dimethyl-2-chloroadenosine. Grades: ≥95%. CAS No. 13406-53-6. Molecular formula: C12H16ClN5O4. Mole weight: 329.74. | |
| 2-Cl-8-HA-cAMP | 2-Cl-8-HA-cAMP is a membrane-permeant cAMP analogue with a preference for site B I of PKA. It can be active to PKA type I in combination with AI-selective analogues. Synonyms: 2- Chloro- 8- n- hexylaminoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C16H23ClN6O6P · Na. Mole weight: 484.8. | |
| 2-Cl-cAMP | 2-Cl-cAMP is a selective cAMP analogue preferring the B sites of both protein kinase A type I and II. Synonyms: 2- Chloroadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 39023-65-9. Molecular formula: C10H10ClN5O6P · Na. Mole weight: 385.6. | |
| 2'-C-Methyl-2-thiouridine | 2'-C-Methyl-2-thiouridine, a modified nucleoside, exhibits antiviral properties and is utilized in the treatment of specific viral infections that include hepatitis C, HIV, and Zika virus. Additionally, investigations are underway for employing this compound in cancer therapy due to its promising outcomes. Synonyms: 2'-β-C-Methyl-2-thiouridine; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-2-sulfanylidenepyrimidin-4-one; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one. Grades: ≥95%. CAS No. 1678507-60-2. Molecular formula: C10H14N2O5S. Mole weight: 274.29. | |
| 2'-C-methyl-5-fluorouridine | 2'-C-methyl-5-fluorouridine, a modified nucleoside, is a compound that has generated substantial interest in the realm of cancer research due to its impressive performance against liver, breast, pancreatic, and colon cancer cells. Considered a promising therapeutic option, the compound's antitumor activity has been rigorously tested and documented, offering a potential solution to some of the deadliest cancers. Synonyms: 2'-β-C-methyl-5-fluorouridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-2'-C-methyluridine. Grades: ≥95%. CAS No. 23643-38-1. Molecular formula: C10H13FN2O6. Mole weight: 276.22. | |
| 2'-C-Methyl-5-methyluridine | 2'-C-Methyl-5-methyluridine is a vital compound in biomedicine used for the development of nucleoside analogs, having applications in the research of diseases like hepatitis C, West Nile virus, and yellow fever. Synonyms: 5-Methyl-2'-C-methyl-uridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-C-Methyl-beta-D-ribofuranosyl)thymine; 2'-β-C-Methyl-5-methyluridine. Grades: ≥95%. CAS No. 119410-84-3. Molecular formula: C11H16N2O6. Mole weight: 272.25. | |
| 2'-C-Methyl-6-S-methyl-6-thioinosine | 2'-C-Methyl-6-S-methyl-6-thioinosine is a robust antiviral compound. Through its potent inhibition of viral replication, it suppresses viral dissemination and diminishes the overall viral burden in the host. Synonyms: 9-(2-C-Methyl-beta-D-ribofuranosyl)-6-(methylsulfanyl)-9H-purine. Grades: 95%. CAS No. 172722-76-8. Molecular formula: C12H16N4O4S. Mole weight: 312.34. | |
| 2'-C-Methyladenosine | 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 μM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 μM. Synonyms: 2-CMA; (2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; 6-Amino-9-(2'-C-methyl-b-D-ribofuranosyl)purine. Grades: ≥95%. CAS No. 15397-12-3. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| 2'-C-Methylcytidine | A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one; 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one; 2'-C-methylcytidine; valopicitabine; Cytidine,2'-C-methyl. Grades: ≥ 95%. CAS No. 20724-73-6. Molecular formula: C10H15N3O5. Mole weight: 257.24. | |
| 2'-C-Methylisoguanosine | 2'-C-Methylisoguanosine, a modified nucleoside, has demonstrated significant antiviral efficacy against hepatitic C and West Nile virus, as well as promising potential in treating cancer, based on existing studies. This compound's effectiveness and distinct chemical structure highlight its potential value as a multifaceted therapeutic agent. Synonyms: 6-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one; 1,2-Dihydro-2'-C-methyl-2-oxoadenosine; Adenosine, 1,2-dihydro-2'-C-methyl-2-oxo-; 2'-β-C-Methyl isoguanosine. Grades: ≥95%. CAS No. 714249-83-9. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| 2'-C-Methyluridine | A2'-C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity. Synonyms: 2'-C-Methyl-1-β-D-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Methyl Uridine; 1,3-bis(N-cyclohexyl)guanidine; 1-(2-C-Methyl-β-D-ribofuranosyl)uracil; 2,4(1H,3H)-pyrimidinedione, 1-(2-C-methyl-β-D-ribofuranosyl)-. Grades: ≥95%. CAS No. 31448-54-1. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| 2'-CMP | 2'-CMP is a metabolite of cytidine-2',3'-cyclic monophosphate. Synonyms: Cytidine- 2'- O- monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 85-94-9. Molecular formula: C9H14N3O8P (free acid). Mole weight: 323.2 (free acid). | |
| 2'-CPC-cAMP | 2'-CPC-cAMP is an analogue of cAMP analogue used for coupling of different labels, dyes or supports with free amino groups. Synonyms: 2'- (5- Carboxypentylcarbamoyl)adenosine-3', 5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C17H23N6O9P. Mole weight: 486.4. | |
| 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -4-fluoro-5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite | 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -4-fluoro-5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite, a critical chemical reagent in the biomedicine industry, demonstrates immense value for the synthesis of nucleosides and nucleotides. Its pivotal role lies within the realm of research and development of pharmaceuticals, particularly anti-cancer and antiviral drugs. CAS No. 2376756-54-4. Molecular formula: C43H52FN8O6P. Mole weight: 826.9. | |
| 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite | 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite, a critical component within the biomedical industry, exhibits remarkable significance. Serving as an essential foundational unit for the synthesis of nucleoside phosphoramidites and diverse bioactive compounds, this compound profoundly impacts the realm of drug discovery, particularly towards the development of innovative antiviral and anticancer agents. CAS No. 182935-50-5. Molecular formula: C38H45FN5O6P. Mole weight: 717.77. | |
| 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite | 2-cyanoethyl ( ( (2S, 3R, 4R, 5R) -5- (2-isobutyramido-6-oxo-1, 6-dihydro-9H-purin-9-yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl) diisopropylphosphoramidite exhibits paramount significance within the biomedical industry. It serves as a vital ingredient in oligonucleotide synthesis for multifarious applications encompassing gene expression analysis, antisense technology, and the pioneering sector of drug development. CAS No. 2376756-55-5. Molecular formula: C44H55N8O7P. Mole weight: 838.93. | |
| 2-Cyanomethylthioadenosine | 2-Cyanomethylthioadenosine, a powerful inhibitor of S-adenosylhomocysteine hydrolase (SAHH), the regulator of methylation pressure and a participant in the development of cancer, is a highly effective modulator of extracellular metabolism, opening doors for therapeutic interventions in cancer, inflammation, and immunomodulation, illuminating its status as a multifaceted agent at the cutting-edge of biochemistry. Grades: ≥95%. CAS No. 2095417-67-5. Molecular formula: C12H14N6O4S. Mole weight: 338.34. | |
| 2'-dcGMP | 2'-dcGMP is an analogue of cGMP, which is a protein kinase G inactive agent. Synonyms: 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 93919-42-7. Molecular formula: C10H11N5O6P · Na. Mole weight: 351.2. | |
| 2'-Deoxy-1-methyl-adenosine Hydriodide | 2'-Deoxy-1-methyl-adenosine Hydriodide is an intermediate in the synthesis of 2'-Deoxy-N-methyladenosine. 2'-Deoxy-N-methyladenosine plays a role in catalytic activity and may promote proper folding of A730 loop. Synonyms: 6-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-1-methyl-9H-purinium Iodide; 2'-Deoxy-1-methyl-adenosine Monohydriodide; N-1-methyl-2'-deoxyribofuranosiladenine iodide; 2'-Deoxy-1-methyladenosine hydroiodide (1:1). CAS No. 74873-17-9. Molecular formula: C11H15N5O3.HI. Mole weight: 393.18. | |
| 2'-Deoxy-1,N6-ethenoadenosine | An etheno DNA-adduct of adenosine found in atherosclerotic lesions in aorta smooth muscle cells induced via lipid peroxidation. A biomarker for genotoxicity. Synonyms: Etheno-2'-deoxy-β-D-adenosine; 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine; 1,N6-Etheno-2'-deoxyadenosine; 1,N6-Etheno-dA; 1,N6-Ethenodeoxyadenosine; Ethenodeoxyadenosine; N1,N6-Etheno-2'-deoxyadenosine; (2R,3S,5R)-2-(hydroxymethyl)-5-(3H-imidazo[1,2-i]purin-3-yl)tetrahydrofuran-3-ol. Grades: ≥95%. CAS No. 68498-25-9. Molecular formula: C12H13N5O3. Mole weight: 275.26. | |
| 2-Deoxy-2,2-difluoroadenosine 5-triphosphate, tetra-lithium salt | | |
| 2-Deoxy-2-chloroadenosine 5-triphosphate, tetra-lithium salt | | |
| 2-Deoxy-2-fluoro-2,6-Diaminopurineriboside | | |
| 2-Deoxy-2-fluoro-2-fluoroadenosine | | |
| 2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine | 2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine is a crucial compound extensively used in biomedicine, acting as a potent nucleoside analog incorporated into RNA molecules to disrupt viral replication processes. This compound has demonstrated promising results in the reserch of RNA viruses, including SARS-CoV-2, Influenza, and Hepatitis C. Synonyms: Uridine, 2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-; 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3-fluorooxolan-2-yl]pyrimidine-2,4-dione; 3',5'-Bis-O-Tert-Butyl(Dimethyl)Silyl)-2'-Deoxy-2'-(R)-Fluoro-Uridine. Grades: ≥95%. CAS No. 139878-36-7. Molecular formula: C21H39FN2O5Si2. Mole weight: 474.71. | |
| 2'-Deoxy-2'-fluoro-3-Deaza-arabinouridine | 2'-Deoxy-2'-fluoro-3-Deaza-arabinouridine, a nucleoside analogue with broad-spectrum antiviral activity, is a promising agent for treating hepatitis B and C, as well as HIV. It acts as a potent inhibitor of viral replication, thereby reducing viral load and susceptibility to infection. Additionally, it exhibits anticancer activity by selectively impairing cancer cell growth and energetics, making it a potentially effective therapeutic for certain malignancies. Synonyms: 4-Hydroxy-1-(2-deoxy-2-fluoro-beta-D-arabinoribofuranosyl)-2(1H)-pyridinone. Grades: ≥95%. CAS No. 2095417-48-2. Molecular formula: C10H12FNO5. Mole weight: 245.20. | |
| 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine | 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine is a nucleoside analog used as an antiviral drug against hepatitis B virus (HBV) and hepatitis C virus (HCV). It inhibits viral polymerase activity and causes chain termination during viral genome replication, thus reducing viral load in infected individuals. This product has potential as a therapeutic agent against other RNA viruses such as Ebola and Zika. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinoribofuanosyl)-2(1H)-pyrimidinone; 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-Arafluorozebularine; 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)pyrimidin-2-(1H)-one. Grades: ≥95%. CAS No. 136675-88-2. Molecular formula: C9H11FN2O4. Mole weight: 230.19. | |
| 2'-Deoxy-2'-fluoro-4'-thio-a-D-arabinouridine | 2'-Deoxy-2'-fluoro-4'-thio-a-D-arabinouridine, a potent and efficacious agent, holds promise in the treatment of a variety of cancers. This treatment obstructs the growth and dissemination of malignant cells, a mechanism particularly effective in addressing hematological malignancies, notably lymphoma and leukemia. Synonyms: 2'-Deoxy-2'-fluoro-4'-thio-α-D-arabinouridine. Grades: ≥95%. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. | |
| 2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine | 2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine, a robust medication utilized in the treatment of various cancers spanning from pancreatic, breast, to colon cancer, ameliorates the condition by hindering DNA synthesis through the suppression of the enzyme ribonucleotide reductase. Furthermore, its multifaceted properties suggest it as an attractive immunosuppressant for tackling autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-; 2'-Deoxy-2'-fluoro-4'-thio-β-D-arabinouridine; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 941610-00-0. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. | |
| 2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine | 2'-Deoxy-2'-fluoro-4-thio-beta-D-arabinouridine, a powerful nucleoside analogue, is a potent antiviral drug with significant therapeutic potential. It is widely employed to combat serious hepatitis B and C virus infections due to its amazing ability to obstruct the reverse transcription of viral RNA to DNA. Hence, it effectively prevents the viral replication and considerably slows down the progression of this devastating condition. Synonyms: 2(1H)-Pyrimidinone, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,4-dihydro-4-thioxo-; 2'-Deoxy-2'-fluoro-4-thio-β-D-arabinouridine. Grades: ≥95%. CAS No. 892145-76-5. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. | |
| 2'-Deoxy-2'-fluoro-4-thiouridine | 2'-Deoxy-2'-fluoro-4-thiouridine, a nucleoside analog, has been shown to be efficacious against diverse cancers, notably pancreatic and liver cancer, owing to its potent RNA synthesis inhibition that halts cancer cells' growth and proliferation. Significantly, it has also exhibited some antiviral potential, especially against viruses such as HIV and hepatitis B, via viral replication inhibition. Synonyms: 1-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)-4-thiouracil; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyrimidin-2(1H)-one; 2'-fluoro-4-thio-2'-deoxy-uridine; 1-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone. Grades: ≥95%. CAS No. 10212-16-5. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. | |
| 2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine | 2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine is a potent antiviral nucleoside analog used in the treatment of viral infections, specifically targeting RNA viruses. It inhibits viral replication by incorporating into viral RNA and terminating its synthesis. This product is commonly used in biomedical research to study the mechanisms of viral replication and to develop new antiviral therapies. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione; 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil; 1-Dfafeu; FEAU; 5-ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 83546-42-3. Molecular formula: C11H15FN2O5. Mole weight: 274.25. | |
| 2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine | 2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine is an exceptional antiviral compound, exhibiting remarkable potential in the research of biomedicine for tackling viral afflictions. Its robustness lies in its ability to suppress viral replication through the selective inhibition of viral polymerase activity, impeding viral RNA synthesis. Uses: Enzyme inhibitors. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; FF-Ara-ura; 5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-fluorouracil. Grades: ≥95%. CAS No. 69123-95-1. Molecular formula: C9H10F2N2O5. Mole weight: 264.18. | |
| 2'-Deoxy-2'-fluoro-5-methoxy-arabinouridine | 2'-Deoxy-2'-fluoro-5-methoxy-arabinouridine is a fascinating and groundbreaking nucleoside analog with remarkable anti-tumor properties to combat multiple cancer types, including the notorious pancreatic cancer. Acting as a nucleoside analogue, this new molecule uniquely integrates into the RNA of malignant cells, thereby stimulating repressed apoptosis via inhibition of RNA synthesis. Remarkably, its remarkable effectiveness as an anticancer agent is currently being validated through heavily monitored clinical trials. Grades: ≥95%. CAS No. 2305415-76-1. Molecular formula: C10H13FN2O6. Mole weight: 276.22. | |
| 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-a-D-arabinouridine | 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-a-D-arabinouridine is a nucleoside analog used as an antiviral drug to treat hepatitis B and C virus infections. It inhibits viral replication by incorporating into viral DNA and terminating chain elongation. It also exhibits antitumor activity by inhibiting DNA synthesis in cancer cells. Synonyms: 1-[(2S,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-alpha-D-arabino-pentofuranosyl)-5-methyluracil; 1-(2-Deoxy-2-fluoro-4-thio-alpha-D-arabinofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-(2-Deoxy-2-fluoro-4-thio-α-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 294868-24-9. Molecular formula: C10H13FN2O4S. Mole weight: 276.28. | |
| 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-beta-D-arabinouridine | 2'-Deoxy-2'-fluoro-5-methyl-4'-thio-beta-D-arabinouridine, a nucleoside analogue with immense potential, has been leveraged to tackle malignant hematologic and solid tumors. Its action initiates with the disruption of cancer cell DNA synthesis, curbing their exuberance and metastasis. Clinical trials have hinted at its efficaciousness in suppressing the growth of leukemia, lymphoma and pancreatic carcinomas, inducing a ray of hope for patients suffering from these ailments. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-5-methyl-; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-5-methyl-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 135123-34-1. Molecular formula: C10H13FN2O4S. Mole weight: 276.28. | |
| 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine | It is an anticancer agent. Synonyms: 2'-Fluoro-5-methyl-1-beta-D-arabinosylcytosine; 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil; 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-; 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-imino-5-methyl-pyrimidin-2-one; 2'-fluoro-5-methylarabino-furanosylcytosine. Grades: ≥95%. CAS No. 78636-53-0. Molecular formula: C10H14FN3O4. Mole weight: 259.23. | |
| 2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine | 2'-Fluoro-5-methyl-1-β-D-arabinofuranosyluracil is the impurity of antiviral drug Clevudine, which is used for Hepatitis B treatment. Synonyms: FMAU; Clevudine; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-methyluracil; 2'-Fluoro-5-methyl-1-β-D-arabinofuranosyluracil; 5-Methyl-2'-fluoroarauracil; D-FMAU. Grades: ≥95%. CAS No. 69256-17-3. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| 2'-Deoxy-2'-fluoro-5'-O-MMT-uridine 3'-CE phosphoramidite | 2'-Deoxy-2'-fluoro-5'-O-MMT-uridine 3'-CE phosphoramidite is a modified uridine used in the synthesis of RNA oligonucleotides for treatment of viral infections, HIV being one such disease. It has strong base-pairing affinity and can be used to modify aptamers, siRNAs and other RNA species. Synonyms: 2'-Deoxy-2'-fluoro-5'-O-MMT-D-uridine 3'-CE phosphoramidite; 2'-Fluoro-5'-O-MMT-2'-deoxyuridine 3'-CE phosphoramidite. Molecular formula: C38H44FN4O7P. Mole weight: 718.77. | |
| 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite | 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite is an indispensable building block employed in the construction of short nucleic acid strands of immense therapeutic significance. This highly purified substance bears remarkable compatibility with diverse biological substrates, rendering it ideal for applications covering a broad spectrum ranging from genetic manipulation to drug discovery. Its profound utility is evidenced by the panacea it represents for numerous life-threatening ailments spanning the dreaded scourge of cancer to the most virulent of infections. Synonyms: 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite; 2'-Fluoro-5'-O-trityl-2'-deoxyuridine 3'-CE phosphoramidite. Molecular formula: C37H42FN4O6P. Mole weight: 688.74. | |
| 2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine | 2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine encapsulates tremendous potential as a powerful antiviral instrument, extensively employed within the biomedical sphere for its formidable prowess against a myriad of RNA viruses, spanning the notorious hepatitis C virus (HCV), the pernicious Zika virus, and the relentless norovirus. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(trifluoromethyl)-. Grades: ≥95%. CAS No. 114652-80-1. Molecular formula: C10H10F4N2O5. Mole weight: 314.19. | |
| 2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine | 2-Deoxy-2-fluoro-6-S-methyl-6-thio-arabino-inosine, a potent nucleoside analog, serves as an effective antiviral medication for treating hepatitis B and C among other viral infections. By suppressing viral polymerase activity, this drug effectively hinders viral replication and dispersal, thereby counteracting the progression of the targeted ailment. Synonyms: 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methylthiopurine; (2R,3R,4S,5R)-4-Fluoro-2-hydroxymethyl-5-(6-methylsulfanyl-purin-9-yl)-tetrahydro-furan-3-ol; (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)oxolan-3-ol; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)-6-(methylsulfanyl)-9H-purine. Grades: ≥95%. CAS No. 109304-12-3. Molecular formula: C11H13FN4O3S. Mole weight: 300.31. | |
| 2'-Deoxy-2'-fluoroadenosine | 2'-Deoxy-2'-fluoroadenosine (CAS# 64183-27-3) is a useful compound for the preparation of AB680, which is a potent and selective inhibitor of CD73. Synonyms: 2'-Fluoro-2'-deoxyadenosine; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9-(2-Fluoro-2-deoxy-beta-D-ribofuranosyl)-purin-6-amine; 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine; 6-Amino-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine. Grades: ≥ 95 %. CAS No. 64183-27-3. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 2-Deoxy-2-fluoroadenosine-3-CE-phosphoramidite | | |
| 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium | 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium is a complex nucleotide analog, frequently employed in advanced biomedical research. The compound has been observed to interact with several essential enzymes, specifically those catalyzing the removal of RNA molecule's 3'-end. Promisingly, 2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium has not only displayed inhibitory properties against viruses such as hepatitis C and HIV but has also shown potential as a therapeutic agent for these viral diseases. Synonyms: [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate di(triethylammonium). Grades: ≥95%. Molecular formula: C22H43FN7O6P. Mole weight: 551.59. | |
| 2-Deoxy-2-fluoroadenosine 5-triphosphate, tetra-lithium salt | | |
| 2-Deoxy-2-fluoroarabinoadenosine-3-CE-phosphoramidite | 2-Deoxy-2-fluoroarabinoadenosine-3-CE-phosphoramidite emerges as a pivotal entity, integrating itself into the intricate framework of nucleic acid solid-phase synthesis to act as an indispensable phosphoramidite building block. By facilitating the seamless incorporation of 2-deoxy-2-fluoroarabinoadenosine into oligonucleotides, it invigorates the therapeutic potential of such entities. Grades: ≥ 95%. | |
| 2-Deoxy-2-fluoroarabinoadenosine 5-triphosphate | | |
| 2-Deoxy-2-fluoroarabinocytidine-3-CE-phosphoramidite | 2-Deoxy-2-fluoroarabinocytidine-3-CE-phosphoramidite is used in biomedicine for the synthesis of modified oligonucleotides for research and diagnostics applications. This product enables the introduction of 2-deoxy-2-fluoroarabinocytidine residues into nucleic acid sequences, facilitating the study of drug resistance and cancer research. Grades: ≥ 95%. | |
| 2-Deoxy-2-fluoroarabinocytidine 5-triphosphate | | |
| 2-Deoxy-2-fluoroarabinoguanosine-3-CE-phosphoramidite | 2-Deoxy-2-fluoroarabinoguanosine-3-CE-phosphoramidite is a paramount instrument extensively utilized within the biomedical realm, facilitates the highly efficient amalgamation of altered oligonucleotides. Tailored meticulously towards the exploration and enhancement of nucleic acid-oriented therapeutics, this derivative of phosphoramidite serving as a pivotal adjunct in the synthesis of oligonucleotide probes. Grades: ≥ 95%. | |
| 2-Deoxy-2-fluoroarabinoguanosine 5-triphosphate | | |
| 2'-Deoxy-2'-fluoroarabinoinosine | 2'-Deoxy-2'-fluoroarabinoinosine is a nucleoside analog used in the treatment of viral infections such as hepatitis C and B. It exhibits potent antiviral activity by inhibiting viral RNA synthesis and acting as a chain terminator during viral genome replication. It has also been studied for its potential use in cancer treatment due to its ability to interfere with DNA synthesis. Synonyms: 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one; 9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine; 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-ol. Grades: ≥95%. CAS No. 98983-40-5. Molecular formula: C10H11FN4O4. Mole weight: 270.22. | |
| 2-Deoxy-2-fluoroarabinonucleoside 5-triphosphates Kit | | |
| 2'-Deoxy-2'-fluoroarabino-O6-methylinosine | 2'-Deoxy-2'-fluoroarabino-O6-methylinosine, a modified nucleoside utilized in RNA synthesis, presents with antiviral properties that have been established to combat hepatitis C virus. Due to this potent antiviral activity, it has been studied and explored as a potential solution for other viral infections such as HIV. Furthermore, research has indicated that the inclusion of this chemical in certain anti-cancer drug treatments may boost their efficacy. Synonyms: (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-methoxypurin-9-yl)oxolan-3-ol; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)-6-methoxy-9H-purine. Grades: ≥95%. Molecular formula: C11H13FN4O4. Mole weight: 284.24. | |
| 2-Deoxy-2-fluoroarabinouridine-3-CE-phosphoramidite | 2-Deoxy-2-fluoroarabinouridine-3-CE-phosphoramidite is a pivotal and fundamental substrate in the realm of biomedicine, finding extensive utility in the synthesis of RNA molecules endowed with alternative configurations. Grades: ≥ 95%. | |
| 2-Deoxy-2-fluoroarabinouridine 5-triphosphate | | |
| 2'-Deoxy-2'-fluoro-b-D-arabino-2-thiouridine | 2'-Deoxy-2'-fluoro-b-D-arabino-2-thiouridine is a potent antiviral nucleoside analogue used for the research of various viral infections. It exhibits inhibitory activity against hepatitis B virus and human immunodeficiency virus (HIV), making it an essential component in antiviral drug cocktails. This compound acts by selectively inhibiting viral reverse transcriptase activity, preventing viral replication and spreading. Synonyms: 4(1H)-Pyrimidinone, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2,3-dihydro-2-thioxo-; 2'-Deoxy-2'-fluoro-β-D-arabino-2-thiouridine. Grades: ≥95%. CAS No. 1006872-85-0. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. | |
| 2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine | 2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine is an pharmacological compound, always applied to research in counteracting a multitude of deleterious viral afflictions. Its remarkable attributes involve the potent suppression of both RNA and DNA viruses, bestowing potential efficacy against the herpes simplex virus, respiratory syncytial virus, and human immunodeficiency virus. Synonyms: 2'-Deoxy-2'-fluoro-β-D-arabino-6-azauridine; 6-Aza-2'-deoxy-2'-arabinofluorouridine; 2-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-1,2,4-triazine-3,5(2h,4h)-dione; 2-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione; 2-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione. Grades: ≥95%. CAS No. 908129-24-8. Molecular formula: C8H10FN3O5. Mole weight: 247.18. | |
| 2'-Deoxy-2'-fluoro-beta-D-arabinocytidine | It is a metabolite of FIAC and an impurity of Azvudine. It is also an anticancer agent. Synonyms: 4-Amino-1-(2-deoxy-2-fluoro-D-arabinofuranosyl)-2(1H)-pyrimidinone; 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine. Grades: ≥95%. CAS No. 56632-83-8. Molecular formula: C9H12FN3O4. Mole weight: 245.21. | |
| 2'-Deoxy-2'-fluorocytidine | 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine demonstrated to inhibit Borna Disease virus replication and spread. Synonyms: 2'-Fluoro-2'-deoxy-β-D-ribofuranosylcytosine; 2'-Fluoro-2'-deoxycytidine; NSC 529432; 4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 10212-20-1. Molecular formula: C9H12FN3O4. Mole weight: 245.21. | |
| 2-Deoxy-2-fluorocytidine-3-CE-phosphoramidite | | |
| 2'-Deoxy-2'-fluorocytidine 5'-monophosphate triethylammonium | 2'-Deoxy-2'-fluorocytidine 5'-monophosphate triethylammonium is a potential biomedical compound product with antiviral efficacy, which has been shown to excel in combating harmful viral invasions, especially those associated with hepatitis C and COVID-19. It is effective in controlling and containing these diseases by inhibiting viral replication and reducing viral burden. Synonyms: [(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate di(triethylammonium); 2'-Deoxy-2'-Fluorocytidine 5'-(Dihydrogen Phosphate) triethylammonium. Grades: ≥95%. Molecular formula: C21H43FN5O7P. Mole weight: 527.57. | |
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