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| Product | Description | |
|---|---|---|
| Drimentine A | It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity. Synonyms: (3S,5aS,10bS,11aS)-10b-[[(1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione; [3S-[3α, 5aα, 10bα(1R*, 4aR*, 8aR*), 11aβ]]-10b-[(Decahydro-5, 5, 8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-6, 10b, 11, 11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1', 2':1, 5]pyrrolo[2, 3-b]indole-1, 4(3H, 5aH)-dione. Grades: >98% by HPLC. CAS No. 204398-90-3. Molecular formula: C32H45N3O2. Mole weight: 503.72. |  |
| Drimentine B | It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity. Synonyms: [5aS-[5aα, 6aβ(1R*, 4aR*, 8aR*), 11aβ]]-6a-[(Decahydro-5, 5, 8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-6, 6a, 11, 11a-tetrahydro-3H-pyrrolo[1'', 2'':4', 5']pyrazino[1', 2':1, 5]pyrrolo[2, 3-b]indole-5, 13(2H, 5aH)-dione. Grades: >98% by HPLC. CAS No. 204398-91-4. Molecular formula: C31H39N3O2. Mole weight: 485.66. | |
| Drimentine C | It is produced by the strain of Actinomycete strain MST-8651. It belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibacterial, antifungal and anthelmintic activity. Synonyms: [5aS-[5aα, 6aβ(1R*, 4aR*, 8aR*), 11aβ, 13aα]]-6a-[(Decahydro-5, 5, 8a-trimethyl-2-methylene-1-naphthalenyl)methyl]-2, 3, 6, 6a, 11, 11a-hexahydro-1H-pyrrolo[1'', 2'':4', 5']pyrazino[1', 2':1, 5]pyrrolo[2, 3-b]indole-5, 13(5aH, 13aH)-dione; (5aS, 6aS, 11aS, 13aS)-6a-(((1S, 4aS, 8aS)-5, 5, 8a-trimethyl-2-methylenedecahydronaphthalen-1-yl)methyl)-1, 2, 3, 6, 6a, 11, 11a, 13a-octahydro-13H-pyrrolo[1'', 2'':4', 5']pyrazino[1', 2':1, 5]pyrrolo[2, 3-b]indole-5, 13(5aH)-dione. Grades: >98% by HPLC. CAS No. 204398-92-5. Molecular formula: C31H41N3O2. Mole weight: 487.68. | |
| Drosophilin A | It is produced by the strain of Drosophila subatrata. It is mainly anti-gram-positive bacterial activity, but also has an inhibitory effect on poliomyelitis Y-SK virus. Synonyms: p-Methoxytetrachlorophenol; Phenol,2,3,5,6-tetrachloro-4-methoxy-; 4-Methoxytetrachlorophenol; Tetrachloro-p-methoxyphenol. CAS No. 484-67-3. Molecular formula: C7H4Cl4O2. Mole weight: 261.92. | |
| Drosophilin C | It is produced by the strain of Drosophila subatrata. It is mainly anti-gram-positive bacterial activity. Synonyms: 3Z-Undecene-5,7,10-triynoic acid; cis-Undec-3-en-5,7,10-triinsaeure; Undec-3c-en-5,7,10-triinsaeure. CAS No. 506-00-3. Molecular formula: C11H8O2. Mole weight: 172.18. | |
| Drosophilin D | It is produced by the strain of Drosophila subatrata. It is mainly anti-gram-positive bacterial activity. Synonyms: 3Z,9,10-undecatriene-5,7-diynoic acid; Undeca-3c,9,10-trien-5,7-diinsaeure; cis-Undeca-3,9,10-trien-5,7-diinsaeure. CAS No. 506-01-4. Molecular formula: C11H8O2. Mole weight: 172.18. | |
| Duazomycin A | Duazomycin A is produced by the strain of Streptomyces ambofaciens. It has the activity of anti-gram-positive bacteria, yeast and yeast-like fungi, and has strong inhibitory effect on sarcoma 180 and adenocarcinoma 755. Synonyms: Duazomycine; Duazomycinum; N-Acetyl-6-diazo-5-oxo-L-norleucine. CAS No. 2508-89-6. Molecular formula: C8H11N3O4. Mole weight: 213.19. | |
| Duclauxin | It is produced by the strain of Penicillum stipitatum. It has inhibitory effect on Ehrlician ascites carcinoma, lymphoma L-5178 and sarcoma 37. Synonyms: 15H-8,15a-Methano-3H,13H-benzo[de]cycloocta[1,2-g_3,4,5-d'e']bis[2]benzopyran-3,9,13,16-tetrone,17-(acetyloxy)-6b,7,8,15b-tetrahydro-4,12-dihydroxy-6b-methoxy-6,10-dimethyl-. CAS No. 1732-37-2. Molecular formula: C29H22O11. Mole weight: 546.48. | |
| Dunaimycin A1 | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It's an immunosuppressant. Synonyms: (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11-trihydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione; 10-Deoxy-Dunaimycin C1. CAS No. 140221-72-3. Molecular formula: C42H72O9. Mole weight: 721.02. | |
| Dunaimycin C1 | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It's an immunosuppressant. Synonyms: (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11,12-tetrahydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione. CAS No. 140221-73-4. Molecular formula: C42H72O10. Mole weight: 737.02. | |
| Dunaimycin D4S | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It has weak anti-bacterial and anti-aspergillus Niger activity, and shows immunosuppressive effect in the mouse popliteal node model. CAS No. 140221-79-0. Molecular formula: C51H89NO14. Mole weight: 940.25. | |
| Duocarmycin A | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has strong antibacterial and antitumor activity. It can inhibit gram-positive bacteria such as Staphylococcus aureus and Streptococcus faecalis (MIC is less than 0.01 μg/mL), it can also inhibit klebsiella pneumoniae (MIC is 0.032 μg/mL), other bacteria and yeast (MIC is 1-10 μg/mL). Synonyms: Antibiotic DC 88A; methyl (6R,7bR,8aS)-6-methyl-4,7-dioxo-2-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,4,5,6,7,8,8a-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylate; Methyl (2R,3bR,4aS)-2-methyl-3,8-dioxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,4,4a,5,6,8-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-2-carboxylate; DUMA; (+)-Dunnione; (+)-duocarmycin A. Grades: ≥95%. CAS No. 118292-34-5. Molecular formula: C26H25N3O8. Mole weight: 507.49. | |
| Duocarmycin B1 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-gram-positive bacteria, gram-negative bacteria and tumor activity. Synonyms: Antibiotic DC 89B1; 1H-Pyrrolo3,2-fquinoline-2-carboxylic acid, 8-bromo-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-; Duocarmycin B(sub 1). Grades: ≥95%. CAS No. 124325-93-5. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Duocarmycin B2 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-tumor activity. Synonyms: DUMB2; Benzo1,2-b:4,3-bdipyrrole-2-carboxylic acid, 8-(bromomethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-. CAS No. 124325-94-6. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Dutomycin | It is produced by the strain of Streptomyces sp. 1725. Dutomycin has stronger cytotoxicity. 1 μg/mL of Dutomycin can completely inhibit P388 leukemia cells. Synonyms: 1,4,6,7(6aH,10H)-Naphthacenetetrone, 8-acetyl-10-((5-((2,6-dideoxy-4-O-(2,4-dimethyl-1-oxo-2-heptenyl)-3-C-methyl-alpha-L-xylo-hexopyranosyl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-10a,11-dihydro-5,6a,9,10a-tetrahydroxy-2-methoxy-12-methyl-, (2S-(2alpha(6aR*, 10S*, 10aS*), 5beta(2Z, 4S*), 6alpha))-. CAS No. 146663-67-4. Molecular formula: C44H54O17. Mole weight: 854.89. | |
| Dykellic acid | It is produced by the strain of Westerdykella multispora F50733. It is an immunologically active substance. It can strongly inhibit LPS-induced B cell proliferation and the production of B cell polyclonal IgM antibody, as well as T cell proliferation. The expression of IL-2 and IL-4 genes in Th cells was inhibited. CAS No. 1097679-78-1. Molecular formula: C14H16O4. Mole weight: 248.27. | |
| Dynamin inhibitory peptide | Has been found to be a peptide inhibitor of the GTPase dynamin and competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. Synonyms: Dynamin inhibitory peptide; 251634-21-6; L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-; QVPSRPNRAP; HY-P1083; AKOS024456770; MS-31983; CS-0027626. Grades: >98%. CAS No. 251634-21-6. Molecular formula: C47H80N18O14. Mole weight: 1121.26. | |
| Dynamin inhibitory peptide, myristoylated | An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Synonyms: AKOS024456771; Dynamin inhibitory peptide,myristoylated; PD079118; S-251634-22-7. Grades: >99%. CAS No. 251634-22-7. Molecular formula: C61H107N19O14. Mole weight: 1330.64. | |
| Dynemicin A | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grades: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47. | |
| Dynemicin L | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylic acid, 8-chloro-5,8,9,14,15,16-hexahydro-1,4,6,17-tetrahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9R,14S,17S,18S)-(9CI). CAS No. 127032-74-0. Molecular formula: C30H22NO9Cl. Mole weight: 575.95. | |
| Dynemicin M | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grades: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49. | |
| Dynemicin N | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylicacid,5,8,9,14,15,16-hexahydro-1,4,6,8,17-pentahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9S,14S,17S,18S)-(9CI). CAS No. 127003-55-8. Molecular formula: C30H23NO10. Mole weight: 557.50. | |
| Dynemicin O | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a,17-hexahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; (8R-(8alpha,9beta,14beta,17S*,18R*))-8,9,14,15-Tetrahydro-1,4,6,8,10,17-hexahydroxy-20-methoxy-18-methyl-9,8,14-(1)butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione. CAS No. 138370-12-4. Molecular formula: C29H23NO10. Mole weight: 545.49. | |
| Dynemicin P | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-3β,4a,6,8,11,14a-hexahydroxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione; 9,8,14-(1)Butanyl(4)ylideneanthra(1,2-b)benz(f)azocine-5,16,19-trione,8,9,14,15-tetrahydro-1,4,6,8,17,20-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*,18R*))-. CAS No. 138370-13-5. Molecular formula: C28H21NO9. Mole weight: 515.47. | |
| Dynemicin Q | It is produced by the strain of Micromonospora chersina M956-1. Although the activity of this antibiotic is lower than Dynemicin A, it still has strong anti-gram-positive bacterial activity, such as Staphylococcus aureus FDA 209P (MIC is 0.08 μg/mL). Synonyms: 9,8,14-(2)Buten(1)yl(4)ylideneanthra(1,2-b)benz(f)azocine-5,6,20-trione,8,9,14,15-tetrahydro-1,4,6,8,17,19-hexahydroxy-18-methyl-, (8R-(8alpha,9beta,14beta,17S*))-. CAS No. 138370-14-6. Molecular formula: C28H19NO9. Mole weight: 513.45. | |
| Ebelactone A | It is produced by the strain of Streptomyces aburaviensis. It has the inhibitory effect on Esterases (IC50 is 0.56 μg/mL), Pancreatic lipase (IC50 is 0.003 μg/mL) and Cutinase on fungal cells. Synonyms: 2-Oxetanone, 4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-3-methyl-, (3S-(3-alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-; (-)-ebelactone a. Grades: ≥98%. CAS No. 76808-16-7. Molecular formula: C20H34O4. Mole weight: 338.48. | |
| Echinocandin B | It is produced by the strain of Aspergillus rugulosus. Echinocandin can inhibit (1,3)-β-Glucan synthase, an essential component of the cell wall of susceptible fungi, and has anti-fungal activity against candida. Synonyms: NSC 287461; 5.1:6-anhydro{(4R,5R)-4,5-dihydroxy-N(2)-[(9Z,12Z)-octadeca-9,12-dienoyl]-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-proline}; Antibiotic A 22082; Antibiotic A 30912 factor A; Antibiotic A 30912A; Antibiotic SL 7810; Antibiotic SL 7810F. Grades: >95% by HPLC. CAS No. 54651-05-7. Molecular formula: C52H81N7O16. Mole weight: 1060.23. | |
| Echinomycin | It is produced by the strain of Streptomyces echinatus. It has the activity of anti-gram-positive bacteria and vaginal trichomonas, and also has the effect on influenza virus and sarcoma 180 cells in vitro. Synonyms: Quinomycin A; Levomycin; N,N'-((1R,4S,7R,11S,14R,17S,20R,24S)-11,24-diisopropyl-2,4,12,15,17,25-hexamethyl-27-(methylthio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28-thia-2,5,12,15,18,25-hexaazabicyclo[12.12.3]nonacosane-7,20-diyl)bis(quinoxaline-2-carboxamide); N-(2-Quinoxalinylcarbonyl)-O-[N-(2-quinoxalinylcarbonyl)-D-seryl-L-alanyl-3-mercapto-N,S-dimethylcysteinyl-N-methyl-L-valyl]-D-seryl-L-alanyl-N-methylcysteinyl-N-methyl-L-valine-(81)-lactone-cyclic(37)-thioether; Antibiotic A 654I; NSC 13502; NSC 526417. Grades: >99% by HPLC. CAS No. 512-64-1. Molecular formula: C51H64N12O12S2. Mole weight: 1101.25. | |
| Echinoserine | It is produced by the strain of Streptomyces tendae Tu 4031. It has anti-gram positive and negative bacteria activity, but lower than Echinomycin. CAS No. 167324-03-0. Molecular formula: C51H68N12O14S2. Mole weight: 1137.28. | |
| Edeine A1 | It is produced by the strain of Bacillus brevis Vm4. It can inhibit DNA replication and protein biosynthesis, and has anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast activities. Synonyms: Glycinamide, N8-[(3S)-3-(4-hydroxyphenyl)-b-alanyl-(2S)-2-hydroxy-b-alanyl-3-amino-L-alanyl]-(3R,4S,8R)-4,8-diamino-8-carboxy-3-hydroxyoctanoyl-N-[3-[(4-aminobutyl)amino]propyl]-(9CI); NSC 663297. CAS No. 27656-72-0. Molecular formula: C33H58N10O10. | |
| Edeine B1 | It is produced by the strain of Bacillus brevis Vm4. It can inhibit DNA replication and protein biosynthesis, and has anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast activities. Synonyms: Glycinamide, N8-[ (3S) -3- (4-hydroxyphenyl) -β -alanyl- (3S) -2-hydroxy-β -alanyl-3-amino-L-alanyl]- (3R, 4S, 8R) -4, 8-diamino-8-carboxy-3-hydroxyoctanoyl-N-[3-[[4- (aminominomethyl) amino]butyl]amino]propyl]-. CAS No. 27656-73-1. Molecular formula: C34H60N12O10. Mole weight: 796.91. | |
| Efrotomycin | It is produced by the strain of Streptomyces lavendulae. The combination of Efrotomycin with the prolonging factor Tu inhibits protein biosynthesis. It has anti-gram-positive bacteria and negative bacteria activity, and it can inhibit coccidiosis in mice and chickens and promote the growth of pigs. Synonyms: Producil; Antibiotic FR 02A; Efrotomicina; Efrotomycine; Mocimycin, 31-O-(6-deoxy-4-O-(6-deoxy-2,4-di-O-methyl-alpha-L-mannopyranosyl)-3-O-methyl-beta-D-allopyranosyl)-1-methyl-. CAS No. 56592-32-6. Molecular formula: C59H88N2O20. Mole weight: 1145.33. | |
| EI-1507-1 | EI-1507-1 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.23 μmol/L. Molecular formula: C20H18O6. Mole weight: 354.35. | |
| EI-1507-2 | EI-1507-2 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.42 μmol/L. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| EI-1511-3 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-3 inhibited recombinant human ICE with an IC50 of 0.09 μmol/L. Synonyms: (2E,4E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-7-methylocta-2,4-dienamide. Molecular formula: C27H30N2O7. Mole weight: 494.54. | |
| EI-1511-5 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-5 inhibited recombinant human ICE with an IC50 of 0.38 μmol/L. Synonyms: (2E,4E,6E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyldeca-2,4,6-trienamide. Molecular formula: C29H32N2O7. Mole weight: 520.57. | |
| EI-1625-2 | It is produced by the strain of Streptomyces sp. E-1625. EI-1625-2 inhibited recombinant human ICE with an IC50 of 0.2 μmol/L. Synonyms: (2E)-N-[(1S,5R,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-4-methyloct-2-enamide. Molecular formula: C27H32N2O7. Mole weight: 496.55. | |
| EI-1941-1 | It is originally isolated from Farrowia sp. E-1941. EI-1941-1 inhibited recombinant human ICE with an IC50 of 0.086 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 2,3-Dihydroxy-5-propyl-1a,5,6,7a-tetrahydro-2H-oxireno[g]isochromen-7(3H)-one. CAS No. 189828-31-7. Molecular formula: C12H16O5. Mole weight: 240.25. | |
| EI-1941-2 | It is originally isolated from Farrowia sp. E-1941. EI-1941-2 inhibited recombinant human ICE with an IC50 of 0.006 μmol/L. It also inhibits elastase and cathepsin. CAS No. 189828-32-8. Molecular formula: C12H14O5. Mole weight: 238.24. | |
| EI-2128-1 | EI-2128-1 is originally isolated from Penicillum sp. E-2128. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 0.59 μmol/L. It also has anti-Gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus and Enterococcus enterococcus. Synonyms: (2E)-N-[(1R,3S,4'S,5R,5'R,7S)-5'-Hydroxy-6-oxodihydro-3'H-spiro[4,8-dioxatricyclo[5.1.0.03,5]octane-2,2'-furan]-4'-yl]-4,6-dimethyl-2-dodecenamide. Molecular formula: C23H35NO6. Mole weight: 421.53. | |
| EI-2346 | EI-2346 is originally isolated from Streptomyces sp. E-2346. It selectively inhibited ICE, and the IC50 of recombinant human ICE was 3.9 μmol/L. It also inhibits elastase and cathepsin. Synonyms: 3,10-Dihydroxy-8-[5-hydroxy-4-(hydroxymethyl)-1,3-dioxan-2-yl]-3-methyl-1-propyl-3,4-dihydro-1H-benzo[g]isochromene-6,9-dione. Molecular formula: C22H26O9. Mole weight: 434.44. | |
| Ekatetrone | It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. | |
| Elaiomycin | It is produced by the strain of Streptomyces hepaticus. It has the activity of anti-gram-positive bacteria and negative bacteria, especially has strong effect on mycobacterium tuberculosis. It is a carcinogen. Synonyms: D-threo-4-Methoxy-3-(1-octenylazoxy)-2-butanol; D-threo-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; (2S,3S)-4-Methoxy-3-(1'-cis-octenyl-cis-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, D-threo-; (E,Z)-(2S,3S)-4-Methoxy-3-(1-octenyl-ONN-azoxy)-2-butanol; 2-Butanol, 4-methoxy-3-(1-octenyl-ONN-azoxy)-, (E,Z)-(2S,3S)-. CAS No. 23315-05-1. Molecular formula: C13H26N2O3. Mole weight: 258.36. | |
| Elasnin | Elasnin is isolated from certain strains of Streptomyces. Elasnin is a reversible inhibitor of elastase with IC50 values of 1.3 and 30 μg/ml for human granulocyte and pancreatic enzymes, respectively. It inhibits human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin with Ki values of 93, 69 and 224 μM, respectively. Synonyms: 3,5-dibutyl-2-hydroxy-6-(6-oxoundecan-5-yl)-4H-pyran-4-one; 3,?5-Dibutyl-6-(1-butyl-2-oxoheptyl)?-4-hydroxy-2H-pyran-2-one. Grades: ≥98%. CAS No. 68112-21-0. Molecular formula: C24H40O4. Mole weight: 392.57. | |
| Elcatonin | Elcatonin is a calcitonin derivative used as an anti-parathyroid agent. Synonyms: Elcatonin Acetate. Grades: 98%. CAS No. 60731-46-6. Molecular formula: C148H244N42O47. Mole weight: 3363.82. | |
| Elizabethin | It is produced by the strain of Streptomyces elizabethii. It has antifungal activity. CAS No. 78361-81-6. Molecular formula: C35H58O12. Mole weight: 670.83. | |
| Elloramycin | It is produced by the strain of Streptomyces olivaceus Tu 2353. It has weak activity against gram-positive bacteria, streptomycete and L-1210 leukemic cells, but has no effect on mouse leukemic P388 cells in vivo, and also has a strong inhibition of Streptomyces (including the production of bacteria themselves) activity. Synonyms: Elloramycin A; methyl (6aR,7S,10aR)-3-[(6-deoxy-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy]-6a,7,12-trihydroxy-8,10a-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate; (6aR)-3-[(2-O,3-O,4-O-Trimethyl-6-deoxy-α-L-mannopyranosyl)oxy]-6,6a,7,10,10a,11-hexahydro-6aα,7α,12-trihydroxy-8,10aα-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylic acid methyl ester. CAS No. 97218-42-3. Molecular formula: C32H36O15. Mole weight: 660.62. | |
| Elsamicin B | Elsamicin B is produced by the strain of Actinomycetes J904-21. It is an antitumor antibiotic in the Chartreusin group. Aminoglycogen-deficient Elsamicin B shows only minimal antitumor activity. Synonyms: 10-[(3-C-Methyl-6-deoxy-β-D-galactopyranosyl)oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione; Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methyl-; 6-Hydroxy-1-methyl-5,12-dioxo-5,12-dihydrobenzo[g][2]benzopyrano[5,4,3-cde][2]benzopyran-10-yl 6-deoxy-3-C-methylhexopyranoside. CAS No. 97068-31-0. Molecular formula: C26H22O10. Mole weight: 494.45. | |
| Elsinochrome A | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: (1r,2r)-1,2-diacetyl-4,11-dihydroxy-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-5,10-dione; 1alpha,2beta-Diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxybenzo[ghi]perylene-4,11-dione; Benzo(ghi)perylene-4,11-dione, 1,2-diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxy-, trans-. Grades: ≥98%. CAS No. 24568-67-0. Molecular formula: C30H24O10. Mole weight: 544.51. | |
| Elsinochrome B | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 1-Acetyl-5,10-dihydroxy-2-(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione. Grades: ≥98%. CAS No. 24512-58-1. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| Elsinochrome C | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 5,10-Dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione; Benzo[ghi]perylene-4,11-dione,1,2-dihydro-5,10-dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-. Grades: ≥98%. CAS No. 24512-87-6. Molecular formula: C30H28O10. Mole weight: 548.54. | |
| Elsinochrome D | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 12,13-Dihydro-2-hydroxy-12,13-bis(1-hydroxyethyl)-1,5,6-trimethoxybenzo[1,12]perylo[2,3-d][1,3]dioxole-3,8-dione. Grades: ≥98%. CAS No. 32500-05-3. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| EM2487 | EM2487 is produced by the strain of Streptomyces sp. Mer-2487. It inhibited HLV-1 replication in both chronically and acutely infected cells. The action occurs during the post-integration phase of the HIV-1 provirus DNA in the HIV-1 replication cycle. Molecular formula: C32H57N5O16P2. Mole weight: 829.76. | |
| Emamectin B1a | It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1a prepared by oxidation of the 4''-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: L 656748; (4''R)-5-O-Demethyl-4''-deoxy-4''-(methylamino)avermectin A1a; 4''-Deoxy-4''-epi-(methylamino)avermectin B1a. Grades: >99% by HPLC. CAS No. 121124-29-6. Molecular formula: C49H75NO13. Mole weight: 886.12. | |
| Emamectin B1b | It is a semi-synthetic 4-epimethylamino analogue of avermectin B1b. It is prepared by oxidation of the 4-hydroxy moiety and reductive amination. It has strong insecticidal efficacy. Synonyms: Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-4''-(methylamino)-25-(1-methylethyl)-, (4''R)-. Grades: >99% by HPLC. CAS No. 121424-52-0. Molecular formula: C48H73NO13. Mole weight: 872.09. | |
| Emerimicin ? | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria. Emerimicin II activity is stronger than the Emerimicin III and IV. Synonyms: samarosporin I; Stilbellin I. CAS No. 52931-43-8. Molecular formula: C77H120N16O19. Mole weight: 1573.87. | |
| Emerimicin IIA | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria and various protozoa. The activity of Emerimicin II is stronger than the Emerimicin III and IV. Synonyms: Ac-Trp-Ile-Gln-Aib-Ile-Thr-Aib-Leu-Aib-Hyp-Gln-Aib-Hyp-Aib-Unk; Zervamicin-II-A; Zervamicin IIA; Zervamicin IC, 3-L-glutamine-4-(2-methylalanine)-; L-Prolinamide, N-acetyl-L-tryptophyl-L-isoleucyl-L-glutaminyl-2-methylalanyl-L-isoleucyl-L-threonyl-2-methylalanyl-L-leucyl-2-methylalanyl-(4R)-4-hydroxy-L-prolyl-L-glutaminyl-2-methylalanyl-(4R)-4-hydroxy-L-prolyl-2-methylalanyl-N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-. CAS No. 79395-86-1. Molecular formula: C89H137N19O22. Mole weight: 1825.15. | |
| Emerimicin IIB | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria and various protozoa. The activity of Emerimicin II is stronger than the Emerimicin III and IV. Synonyms: Zervamicin IIB; N-acetyl-L-tryptophyl-L-isoleucyl-L-glutaminyl-L-isovalyl-L-isoleucyl-L-threonyl-alpha-methyl-alanyl-L-leucyl-alpha-methyl-alanyl-(4R)-4-hydroxy-L-prolyl-L-glutaminyl-alpha-methyl-alanyl-(4R)-4-hydroxy-L-prolyl-alpha-methyl-alanyl-L-prolyl-L-phenylalaninol; Ac-Trp-Ile-Gln-Iva-Ile-Thr-Aib-Leu-Aib-Hyp-Gln-Aib-Hyp-Aib-Pro-Phe-ol; Zervamicin IC, 3-L-glutamine-. CAS No. 79395-85-0. Molecular formula: C90H139N19O22. Mole weight: 1839.18. | |
| Emerimicin III | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria. Emerimicin II activity is stronger than the Emerimicin III and IV. Synonyms: samarosporin II; Stilbellin II; Antibiotic EM 3. CAS No. 52931-42-7. Molecular formula: C76H118N16O19. Mole weight: 1559.84. | |
| Emerimicins | It is produced by the strain of Emericellopsis microspora. It mainly has activity against gram-positive bacteria. Emerimicin II activity is stronger than the Emerimicin III and IV. Synonyms: Emerimicin; Peptaibols. CAS No. 71812-28-7. Molecular formula: C162H249N35O41. Mole weight: 3342.92. | |
| Emerin | It is produced by the strain of Aspergillus nidulans. Emerin is an antibiotic. Emerin is a protein that in humans is encoded by the EMD gene, also known as the STA gene. Mutations in emerin cause X-linked recessive Emery-Dreifuss muscular dystrophy, cardiac conduction abnormalities and dilated cardiomyopathy. Synonyms: Epurpurin C dimethyl ether; Emerin (Aspergillus); Butanedinitrile, bis((4-methoxyphenyl)methylene)-, (Z,Z)-. CAS No. 40581-18-8. Molecular formula: C20H16N2O2. Mole weight: 316.35. | |
| Emestrin | It is produced by the strain of Mycotoxin EQ-1 Emericella sp. It has strong antifungal activity. Synonyms: emestrin A; Emestrine. Grades: >95%. CAS No. 97816-62-1. Molecular formula: C27H22N2O10S2. Mole weight: 598.60. | |
| Emimycin | It is produced by the strain of Streptomyces sp. 2020-I. It has anti-gram-positive bacteria, negative bacteria and brewer's yeast and other fungal activities. Synonyms: Enimycin; Pyrazinol, 4-oxide; 2(1H)-Pyrazinone, 4-oxide; 2-Hydroxypyrazine 4-oxide; 1,2-Dihydro-2-oxopyrazine 4-oxide; 4-oxidanidyl-1H-pyrazin-4-ium-2-one. CAS No. 3735-46-4. Molecular formula: C4H4N2O2. Mole weight: 112.09. | |
| Empedopeptin | Empedopeptin is produced by the strain of Empedobacter haloabium G393-B445. It has anti-gram-negative bacterial activity. Synonyms: Antibiotic BMY 28117; Antibiotic BU2517. CAS No. 87551-98-2. Molecular formula: C49H79N11O19. Mole weight: 1126.22. | |
| Enactin Ia | It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Synonyms: EN-Ia; 19-hydroxyneoenactin B2; (S)-2-Amino-3,N-dihydroxy-N-(15-hydroxy-15-methyl-3,10-dioxo-hexadecyl)-propionamide. CAS No. 130640-30-1. Molecular formula: C20H38N2O6. Mole weight: 402.53. | |
| Enactin Ib | It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Synonyms: EN-Ib. CAS No. 137252-26-7. Molecular formula: C20H38N2O6. Mole weight: 402.53. | |
| Enactin-Va | It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Synonyms: EN-Va; 14-dihydroneoenactin M1; (S)-2-Amino-3,N-dihydroxy-N-(10-hydroxy-14-methyl-3-oxo-pentadecyl)-propionamide. CAS No. 130640-31-2. Molecular formula: C19H38N2O5. Mole weight: 374.52. | |
| Enacyloxin IIa | It is produced by the strain of Frateuria sp. W-315. It is a polyene antibiotic, which has the activity of anti-gram-positive bacteria and negative bacteria. the activity of anti-fungus is weak, and has no effect on yeast. Synonyms: (1S, 3R, 4S)-3-{[(2E, 4E, 6E, 8E, 10Z, 12S, 13R, 14S, 17R, 18S, 19R, 20E)-19-(carbamoyloxy)-11, 18-dichloro-13, 14, 17-trihydroxy-6, 12-dimethyl-15-oxotricosa-2, 4, 6, 8, 10, 20-hexaenoyl]oxy}-4-hydroxycyclohexanecarboxylic acid; Enacyloxin II; Enacyloxin iia; Enx iia. CAS No. 126518-41-0. Molecular formula: C33H45Cl2NO11. Mole weight: 702.62. | |
| Enamidonin | It is produced by the strain of Streptomyces sp. 91-75. It's a lipopeptide antibiotic. It inhibits EGF-dependent [3H] thymidine involvement in Balb/MK cells (IC50 is 10 μg/mL), and it can restore the deformed SRCTS-NRK form to the normal flat form (ED50 is 10 μg/mL). No antimicrobial activity. Synonyms: Antibiotic RK 75. CAS No. 162559-40-2. Molecular formula: C37H51N7O7. Mole weight: 705.84. | |
| Enaminomycin A | It is produced by the strain of Streptomyces baarnensis 13120. It has activity against gram-positive bacteria, gram-negative bacteria and plant pathogenic fungi (weak), and it has the inhibitory effect of L-1210. Synonyms: (1S,6R)-4-amino-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid. CAS No. 68330-49-4. Molecular formula: C7H5NO5. Mole weight: 183.12. | |
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