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Used in the solid phase synthesis of peptides which are difficult to make. Synonyms: Fmoc-Ala-Thr[y(Me,Me)Pro]-OH; (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylic acid; Fmoc-Ala-Thr(psi(Me,Me))-OH; Fmoc-Ala-Thr(y(Me,Me))-OH; (4S,5R)-3-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoyl]-2,2,5-trimethyl-1,3-oxazolidine-4-carboxylic acid. Grades: 95-105% (Assay by titration). CAS No. 252554-79-3. Molecular formula: C25H28N2O6. Mole weight: 452.51.
Fmoc-Ile-Ser[Psi(Me,Me)Pro]-OH is used as a reactant in the synthesis of peptides and receptor targeting ligands. Synonyms: Fmoc-Ile-Ser[Psi(Me,Me)Pro]-OH; (S)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-isoleucinyl]-2,2-dimethyloxazolidine-4-carboxylic acid; Fmoc-Ile-Ser(Psime,Mepro)-OH; 6904AH; (4S)-3-[(2S,3S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid. Grades: 99-101% (Assay by titration). CAS No. 1147996-34-6. Molecular formula: C27H32N2O6. Mole weight: 480.56.
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH is used as a reactant in the synthesis of peptides and proteins. Synonyms: Fmoc-Ser(tBu)-Ser[Ψ(Me,Me)Pro]-OH; (S)-3-[Nα-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-serinyl]-2,2-dimethyloxazolidine-4-carboxylic acid; Fmoc-Ser(Tbu)-Ser(Psime,Mepro)-OH; (4S)-3-[(2S)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid; Fmoc-L-Ser(tBu)-L-Ser(Psi(Me,Me)pro)-OH; (S)-3-((S)-2-(((E)-((9H-fluoren-9-yl)methoxy)(hydroxy)methylene)amino)-3-(tert-butoxy)propanoyl)-2,2-dimethyloxazolidine-4-carboxylic acid. Grades: ≥ 98.5% (HPLC). CAS No. 1000164-43-1. Molecular formula: C28H34N2O7. Mole weight: 510.58.
Folipastatin is a fungal metabolite that is produced by A. unguis. Folipastatin is also an inhibitor of phospholipase A2 (PLA2) with an IC50 of 39 μM. Synonyms: 3,8-dihydroxy-4,9-dimethyl-1,6-bis[(1Z)-1-methyl-1-propen-1-yl]-11H-dibenzo[b,e][1,4]dioxepin-11-one; E323392EAO. Grades: ≥95%. CAS No. 139959-71-0. Molecular formula: C23H24O5. Mole weight: 380.43.
Forchlorfenuron
Forchlorfenuron is a plant growth regulator that increases the size of the fruit. It acts synergistically with auxin hormones to promote growth. It is considered a dangerous product. Uses: Plant growth regulator (pgr). Synonyms: CPPU. CAS No. 68157-60-8. Molecular formula: C12H10ClN3O. Mole weight: 247.68.
It is produced by the strain of Flexibacter alginolique faciens sp. It has strong activity against kinds of pseudomonas, proteobacteria and alkaline-producing bacilli. Synonyms: (3S, α R) -3- [ [ (R) - [4- [ (R) -3-Amino-3-carboxypropoxy] phenyl] hydroxyacetyl] amino] -3-formylamino-α - [4- [ (β -D-glucopyranuronosyl) oxy] phenyl] -2-oxo-1-azetidineacetic acid; Antibiotic PA-42702B; Antibiotic TAN-585A. CAS No. 99150-60-4. Molecular formula: C30H34N4O16. Mole weight: 706.61.
Formamicin
Formamicin is produced by the strain of Saccharothrix sp. MK27-91F2. It has broad spectrum and strong anti-plant pathogenic fungi activity, with MIC of 0.39-12.5μg/mL. It also has moderate gram-positive bacterial activity. It is cytotoxic. Synonyms: (1S,3E,5E,7S,8R,11E,13E,15S,19S,20S)-8-[(1S,2R,3S)-3-[(2R,4R,5R,6R)-4-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2-hydroxy-5,6-dimethyl-tetrahydropyran-2-yl]-2-hydroxy-1-methyl-butyl]-20-hydroxy-7-methoxy-3,13,15-trimethyl-19-pentyl-9,16,18-trioxabicyclo[13.4.1]icosa-3,5,11,13-tetraen-10-one. Molecular formula: C44H72O13. Mole weight: 809.03.
For-Met-Ala-Ser-OH
For-Met-Ala-Ser-OH is a peptide that binds to a formyl-peptide receptor on neutrophils. Synonyms: Formyl-MAS; N-Formyl-Met-Ala-Ser; formyl methionyl alanyl serine; N-formyl-L-methionyl-L-alanyl-L-serine; (S)-2-((S)-2-((S)-2-formamido-4-(methylthio)butanamido)propanamido)-3-hydroxypropanoic acid. Grades: ≥97% by HPLC. CAS No. 17351-32-5. Molecular formula: C12H21N3O6S. Mole weight: 335.38.
Formyl-L-methionine is a protein amino acid present in the organelles of bacteria and related eukaryotes. It is a derivative of the amino acid methionine, in which a formate is added to the amino group of the methionine. It plays a crucial role in protein biosynthesis in bacteria, Mitochondria and chloroplasts. But it is not used for protein biosynthesis in Eukaryotic Cytosol, in which only the nuclear genes are translated. It's also not used in ARCHAEA. In humans, it is recognized by the immune system as a foreign substance and stimulates the body to fight potential infections. Synonyms: For-L-Met-OH; N-Formyl-L-methionine; 2-formamido-4-methylsulfanylbutanoic acid; N-Formyl-L -Methionine; L-Methionine, N-formyl-;(S)-2-Formamido-4-(methylthio)butanoic acid. Grades: ≥ 98% (HPLC). CAS No. 4289-98-9. Molecular formula: C6H11NO3S. Mole weight: 177.22.
Produced by the strain of Micromonospora olivoasterospora, it has a weak antibacterial activity. Synonyms: Astromicin B; 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol. CAS No. 54783-95-8. Molecular formula: C15H32N4O5. Mole weight: 348.44.
Fosfadecin
Fosfadecin is produced by the strain of Pseudomonas fluorescens PK-5. It has a weak antibacterial activity, the ED50 of Escherichia coli O-111 and Staphylococcus aureus 308A-1 was 800mg/kg and 566mg/kg (mice, oral). Synonyms: Tan 930; 9-[5-O- (Hydroxy{[hydroxy (3-methyloxiran-2-yl) phosphoryl]oxy}phosphoryl) pentofuranosyl]-9H-purin-6-amine. CAS No. 120909-50-4. Molecular formula: C13H19N5O10P2. Mole weight: 467.27.
Fosfazinomycin A
Fosfazinomycin A is produced by the strain of Streptomyces lavendofoliae. It has the activity of resisting plant pathogenic fungi such as Xanthomonas oryzae. Molecular formula: C15H32N7O7P. Mole weight: 453.43.
Fosfazinomycin B
Fosfazinomycin B is produced by the strain of Streptomyces lavendofoliae. It has the activity of resisting plant pathogenic fungi such as Xanthomonas oryzae. Synonyms: L-Arginine 2-[hydroxy(1-hydroxy-2-methoxy-2-oxoethyl)phosphinyl]-2-methyl hydrazide. CAS No. 87423-11-8. Molecular formula: C10H23N6O6P. Mole weight: 354.30.
Fosfocytocin
It is produced by the strain of Pseudomonas fluorescens PK-52. It has very weak antibacterial activity. Synonyms: Tan 1022; Cytidine 5'-(trihydrogen diphosphate), P'-(2-(formylhydroxyamino)ethyl) ester; 1-{5-O-[{[{2-[Formyl (hydroxy)amino]ethoxy} (hydroxy)phosphoryl]oxy} (hydroxy)phosphoryl]pentofuranosyl}-4-imino-1, 4-dihydropyrimidin-2-ol. CAS No. 126986-25-2. Molecular formula: C12H20N4O13P2. Mole weight: 490.25.
Fosfomycin calcium
Fosfomycin calcium is the calcium salt form of Fosfomycin, produced by Streptomyces. Fosfomycin is an antibiotic that is primarily used to treat bladder infections. Fosfomycin inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. Synonyms: Phosphomycin calcium; Phosphonomycin calcium; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt; Phosphonic acid, (1,2-epoxypropyl)-, calcium salt, cis-(-)-; Phosphonic acid, (3-methyloxiranyl)-, calcium salt, (2R-cis)-. Grades: ≥98%. CAS No. 26472-47-9. Molecular formula: C3H7O4P.xCa. Mole weight: 138.06 (free acid).
Fosfonochlorin
It is produced by the strain of Talaromyces flavus SANK 15680 and Fusarium oxysporum SANK 10182. Chloroacetylphosphoric acid only has the activity of anti-proteus bacteria, but in the presence of glucose-6-phosphate (G-6-P), it is also effective against Staphylococcus aureus, Escherichia coli, Haemophilus haemophilus, some Shigella and Salmonella bacteria. The mechanism of antibacterial action is to inhibit cell wall biosynthesis and affect the formation of plasmoglobin. Synonyms: (chloroacetyl)phosphonic acid; Chloroacetylphosphonate. Grades: 98%. CAS No. 89699-33-2. Molecular formula: C2H4ClO4P. Mole weight: 158.48.
Fosmidomycin sodium salt
Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grades: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08.
Fostriecin
The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Synonyms: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grades: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39.
FR-182877
FR-182877 is produced by the strain of Streptomyces sp. No. 9885. It has a strong effect on rat ascites and solid tumors in vivo, and has no antibacterial activity. Molecular formula: C24H32O5. Mole weight: 400.51.
FR-191512
It is a polyphenolic compound with anti-influenza A virus effect. Synonyms: FR191512. Molecular formula: C38H38O16. Mole weight: 750.70.
FR-198248
FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Synonyms: fr198248; 1,3-Dihydro-4-methyl-1,5,6,7-isobenzofurantetraol. Grades: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17.
FR225659
FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21.
FR-235222
FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Synonyms: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69.
FR 252921
FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67.
FR-252922
FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72.
FR-29038
It is originally isolated from Nocardia uniformis subsp. tsuyamanensis. FR-29038 has anti-Bacillus, Escherichia, Klebsiella, Pseudomonas, Salmonella, Shigella and other family bacteria activities. Synonyms: Antibiotic FR 29038; BRN 3578863; O-{4-[1-Amino-2-({1-[carboxy(4-hydroxyphenyl)methyl]-2-oxoazetidin-3-yl}imino)-2-hydroxyethyl]phenyl}homoserine. CAS No. 59511-12-5. Molecular formula: C23H26N4O8. Mole weight: 486.47.
FR 32863
FR 32863 is produced by the strain of Streptomyces lavendulae 8006. FR 32863 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 32863; Antibiotic FR 900136; BRN 2092108; FR-32863; (E)-(3-(Formylhydroxyamino)-1-propenyl)phosphonic acid. CAS No. 66508-88-1. Molecular formula: C4H8NO5P. Mole weight: 181.08.
FR-33289
FR-33289 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-33289 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 33289; (R)-(3-(Acetylhydroxyamino)-2-hydroxypropyl)phosphonic acid. CAS No. 73240-15-0. Molecular formula: C5H12NO6P. Mole weight: 213.13.
FR 65814
FR 65814 is originally isolated from Penicillum jensenii F-2883. It has a strong immunosuppressive effect, and the IC50 of inhibiting mixed lymphocyte reaction (MLR) in mice is 34 nmol/L. Synonyms: 4-(2-Methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2.5)octane-5,6-diol. CAS No. 103470-60-6. Molecular formula: C15H24O4. Mole weight: 268.35.
FR 66979
FR 66979 is produced by the strain of Streptomyces sandaensis No. 6897. It has inhibitory activity against tumor cells, including leukemia P388 cells and melanoma B16 cells. Synonyms: [7,9-Dihydroxy-5-(hydroxymethyl)-1,1a,2,8,9,9a-hexahydro-3,9-epoxyazireno[2,3-c][1]benzazocin-8-yl]methyl hydrogen carbonimidate. Grades: 97%. CAS No. 102409-60-9. Molecular formula: C14H17N3O6. Mole weight: 323.30.
FR 900109
It is produced by the strain of Streptomyces prunicolor. FR 900109 has anti-gram-positive bacteria activity. Synonyms: Antibiotic FR900109; FR900109. CAS No. 83512-61-2. Molecular formula: C27H32O9. Mole weight: 500.54.
FR 900130
FR 900130, isolated from Streptomyces catenulae, is an antibiotic easily to decompose. It has anti-gram-positive and anti-gram-negative activities, and has a synergistic effect with D-cycloserine. Synonyms: L-2-amino-3-butynoic acid; Antibiotic FR 900130; (S)-2-Amino-3-butynoic acid. Grades: >95%. CAS No. 73537-09-4. Molecular formula: C4H5NO2. Mole weight: 99.09.
FR 900137
FR 900137 is produced by the strain of Streptomyces unzenensis 2050. It has a broad spectrum of antibacterial activity and has a strong effect on Pseudomonas aeruginosa ?. Synonyms: Antibiotic FR 900137; L-Leucine, 2-(hydroxymethoxyphosphinyl)-2-methylhydrazide; 2-Amino-N-[hydroxy(methoxy)phosphoryl]-N,4-dimethylpentanehydrazonic acid. CAS No. 73706-58-8. Molecular formula: C8H20N3O4P. Mole weight: 253.24.