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6-Deoxy-L-talitol
6-Deoxy-L-talitol, a remarkable sugar alcohol with immense potential, finds widespread application in the biomedical realm. Championed for its vital role in drug development targeting diabetes, metabolic disorders, and cardiovascular ailments, this compound stands as a cornerstone of scientific progress. Synonyms: L-Altritol, 1-deoxy-; 1-Deoxy-L-altritol; Talitol, 6-deoxy-. CAS No. 73804-38-3. Molecular formula: C6H14O5. Mole weight: 166.17.
6-Deoxy-L-talose
6-Deoxy-L-talose, an imperative entity within the biomedical sphere, finds application in the progression of pharmaceutical interventions aiming to combat a myriad of ailments. With its ubiquitous integration in medicinal exploration, 6-Deoxy-L-talose assumes a pivotal function, propelling the advancement of biomedical therapies and enhancing health-related consequences for individuals. Synonyms: 2-Deoxy-1,3-myo-inosadiame. CAS No. 7658-10-8. Molecular formula: C6H12O5. Mole weight: 164.16.
6-Deoxypenciclovir
6-Deoxypenciclovir is a metabolite of Famciclovir, an antiviral used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: Famciclovir related compound A; 2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,3-propanediol; Di-desacetyl Famciclovir; BRL 42359; 2-(2-(2-Amino-9H-purin-9-yl)ethyl)propane-1,3-diol; 2-amino-9-(4-hydroxy-3-(hydroxymethyl)but-1-yl)purine. Grade: ≥98% by HPLC. CAS No. 104227-86-3. Molecular formula: C10H15N5O2. Mole weight: 237.26.
6-Desacetyl-6-Bromo Palbociclib
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 6-Bromo-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one; Pyrido-[2,3-d]-pyrimidin-7-one 41. CAS No. 851067-56-6. Molecular formula: C22H26BrN7O. Mole weight: 484.402.
6-Desacetyl-6-Bromo Palbociclib Hydrochloride
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 6-bromo-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride. CAS No. 850918-83-1. Molecular formula: C22H27ClBrN7O. Mole weight: 520.86.
6-Desacetyl Palbociclib
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-; Pyrido-[2,3-d]-pyrimidin-7-one 38. CAS No. 571190-22-2. Molecular formula: C22H27N7O. Mole weight: 405.506.
6-Desacetyl Palbociclib Hydrochloride
An impurity of Palbociclib, a selective inhibitor of cyclin-dependent kinases CDK4 and CDK6. Palbociclib is developed for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride. CAS No. 571189-66-7. Molecular formula: C22H28ClN7O. Mole weight: 441.96.
6-Desamino-6-[4-chlorophenyl]-sulfinyladenosine 2'3'-O-(Methylethylidene) is an intermediate in the synthesis of Succinoadenosine, a biochemical marker of adenylosuccinase deficiency-the genetic defect of purine de novo synthesis. Molecular formula: C19H19ClN4O5S. Mole weight: 450.9.
6-Desamino-6-(4-Chlorophenyl)-thioadenosine 2',3'-O-(1-Methylethylidene) is an intermediate in the synthesis of Succinoadenosine, a biochemical marker of adenylosuccinase deficiency-the genetic defect of purine de novo synthesis. Molecular formula: C19H19ClN4O4S. Mole weight: 434.9.
6-Desaminoethyl Pixantrone
6-Desaminoethyl Pixantrone is a derivative of Pixantrone, which is a synthetic and noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Synonyms: 6-Amino-9-[(2-aminoethyl)amino]benz[g]isoquinoline-5,10-dione; Benz[g]isoquinoline-5,10-dione, 6-amino-9-[(2-aminoethyl)amino]-. Grade: ≥95%. CAS No. 1430561-04-8. Molecular formula: C15H14N4O2. Mole weight: 282.30.
6-Desfluoro-6-hydroxy-risperidone
An impurirty of Risperidone,Risperidone is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Synonyms: 6,7,8,9-Tetrahydro-3-[2-[4-(6-hydroxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Grade: > 95%. CAS No. 106266-11-9. Molecular formula: C23H28N4O3. Mole weight: 408.5.
6-(des-t-butyl-D-serine)-goserelin
6-(des-t-butyl-D-serine)-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser-Tyr-D-Ser-Leu-Arg-Pro-NHNHCONH2; (S)-N-((6S,9S,12S,15S,18S,21S,24S)-21-((1H-indol-3-yl)methyl)-1-amino-6-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-12,18-bis(hydroxymethyl)-25-(1H-imidazol-5-yl)-1-imino-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-yl)-5-oxopyrrolidine-2-carboxamide. Molecular formula: C55H76N18O14. Mole weight: 1213.33.
6-(Diethylamino)spiro[isobenzofuran-1(3H),9-[9H]xanthen]-3-yl b-D-galactopyranoside, also known as DEASIBFXG, is an essential biomedical tool in the realm of pharmaceutical innovation. Primarily engineered for unravelling the elusive cellular targets, it propels the research of oncology, infectious ailments and enigmatic neurological disorders. Synonyms: HMDER-bGAL; (2S,3R,4S,5R,6R)-2-((3'-(diethylamino)-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 6'-(Diethylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl β-D-galactopyranoside. CAS No. 1326231-95-1. Molecular formula: C30H33NO8. Mole weight: 535.58.
6-(Diethylamino)spiro[isobenzofuran-1(3H),9-[9H]xanthen]-3-yl b-D-glucopyranoside is a vital compound, possessing prodigious potential for investigating the intricate mechanisms underlying glucose metabolism across diverse pathological states and the advancement of pharmaceuticals. It is endowed with the remarkable capability to modulate designated enzymes and receptors implicated in glucose regulation. Synonyms: (2S,3R,4S,5S,6R)-2-((3'-(diethylamino)-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 6'-(Diethylamino)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl β-D-glucopyranoside. Molecular formula: C30H33NO8. Mole weight: 535.58.
6-Dimethylaminopurine
6-Dimethylaminopurine is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes. Uses: Protein kinase inhibitors. Synonyms: N6,N6-Dimethyladenine; N,N-Dimethyl-1H-purin-6-amine; N,N-Dimethyl-adenine; 6-DMAP; DMAP; N,N-Dimethyladenine. Grade: > 98%. CAS No. 938-55-6. Molecular formula: C7H9N5. Mole weight: 163.18.
6-Epi-castanospermine
6-Epi-castanospermine is a remarkably efficacious suppressant of α-glucosidases and glycosidase, exhibiting unparalleled potential for studying afflictions including cancer, diabetes and viral infections. Synonyms: (1S,6R,7R,8R,8aR)-Octahydroindolizine-1,6,7,8-tetraol; 6-Epicastanospermine; 1,6,7,8-Indolizinetetrol, octahydro-, (1S,6R,7R,8R,8aR)-; (+)-6-Epicastanospermine; (+)-6-epi-Castanospermine; 1,6,7,8-Indolizinetetrol, octahydro-, (1S-(1alpha,6alpha,7alpha,8beta,8abeta))-. Grade: 95%. CAS No. 107244-34-8. Molecular formula: C8H15NO4. Mole weight: 189.21.
6-epi-Ophiobolin C
6-epi-Ophiobolin C is a remarkable compound, used in studying a myriad of afflictions with unparalleled antifungal and antibacterial might. Synonyms: epi-6-Ophiobolin C. CAS No. 178152-19-7. Molecular formula: C25H38O3. Mole weight: 386.57.
6-Ethoxy-2-benzothiazolesulfonamide
Ethoxzolamide is used in the treatment of glaucoma, and is also used as a diuretic, acting as a carbonic anhydrase inhibitor. Uses: Acting as a carbonic anhydrase inhibitor. Synonyms: 6-ethoxy-1,3-benzothiazole-2-sulfonamide. Grade: ≥ 98 %. CAS No. 452-35-7. Molecular formula: C9H10N2O3S2. Mole weight: 258.32.
6-Ethylmercaptopurine
6-Ethylmercaptopurine, a pharmacological agent specialized for the therapeutic intervention of acute lymphoblastic leukemia (ALL), suppresses DNA biogenesis during cellular division, with consequential fatality of malignant cells. To achieve optimal therapeutic outcomes, 6-Ethylmercaptopurine is frequently combined with other chemotherapy agents in the treatment of ALL. Synonyms: 6-(ethylthio)purine; 6-(ethylthio)-7H-purine; 6-Ethylthiopurine; 6-Ethyl MP; 6-(ethylsulfanyl)-9H-purine; 1H-Purine, 6-(ethylthio)-; 6-(Ethylsulfanyl)-1H-purine. Grade: ≥98% by HPLC. CAS No. 5417-84-5. Molecular formula: C7H8N4S. Mole weight: 180.23.
6-Ethynyl-4,4-Dimethyl Thiochroman
One of the impurities of Tazarotene, which is an active metobolite of Tazarotene and could be used in the treatment of photodamaged skin. Synonyms: 6-ethynyl-4,4-dimethyl-thiochroman. Grade: > 95%. CAS No. 118292-06-1. Molecular formula: C13H14S. Mole weight: 202.32.
6'-Exomethylene Lovastatin
6'-Exomethylene Lovastatin is a metabolite of Lovastatin which is an antihypercholesterolemic agent. Synonyms: (2S)-2-Methyl-butanoic Acid (1S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-7-methyl-3-methylene-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; 2-Methyl-butanoic acid [1S-[1α(R*),7β,8β(2S*,4S*),8aβ]]-1,2,3,7,8,8a-Hexahydro-7-met. Grade: > 95%. CAS No. 121624-17-7. Molecular formula: C24H34O5. Mole weight: 402.52.
6-FAM-11-dCTP
6-FAM-11-dCTP, a modified nucleotide employed in molecular biology experimentation, is a highly sought-after material for labeling DNA and RNA. Its employment is particularly useful in fluorescence in situ hybridization (FISH) and DNA sequencing. With use in DNA probe labeling, 6-FAM-11-dCTP is of interest in the detection of genes and mutations linked to diseases including genetic disorders and cancer. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]-2'-deoxycytidine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grade: ≥ 95%.
6-FAM-11-dUTP
6-FAM-11-dUTP is a highly sought-after fluorescent nucleotide derivative in the field of compound research, employed as a distinguished probe. It bestows the ability to proficiently label DNA and RNA fragments within versatile frameworks like DNA sequencing, PCR compound labeling and even in situ hybridization. Consequently, this exceptional compound unfailingly facilitates the visualization and detection of nucleic acids, thereby cementing its worthiness as an indispensable tool in both molecular biology and diagnostics. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]-2'-deoxyuridine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grade: ≥ 95%.
6-FAM-11-UTP
6-FAM-11-UTP is a fluorescent nucleotide analog, possessing the ability to be seamlessly integrated into RNA during the transcription process. This unique characteristic facilitates the visual exploration and identification of RNA molecules, empowering researchers to unravel the intricate workings of these vital biomolecules. Its diverse applications encompass a wide range of studies such as transcriptional investigations, RNA labeling endeavors and the real-time tracking of mRNA research and development. Synonyms: 5-[3-(6-(fluoresceinyl-6-carboxamido)hexanoylamido)-propenyl]- uridine-5'-triphosphate, triethylammonium or tetralithium (optional) salt. Grade: ≥ 95%.
6-FAM-dC-puromycin
6-FAM-dC-puromycin is a valuable tool in the biomedical industry for studying protein research and development and translation. This compound functions as an RNA mimic, incorporating 6-FAM and dC residues into nascent peptide chains during translation. It enables visualization and tracking of newly synthesized proteins in live cells. 6-FAM-dC-puromycin is particularly useful in researching diseases related to protein research and development and signaling pathways. Grade: ≥ 95% by HPLC. CAS No. 436083-76-0. Molecular formula: C58H65N11O20P2 (free acid). Mole weight: 1298.15 (free acid).
6-FAM-DMT-phosphoramidite
6-FAM-DMT Phosphoramidite is a phosphoramidite derivative used to introduce 6-carboxyfluorescein (6-FAM) into oligonucleotides during solid-phase synthesis. It includes a 6-FAM fluorophore and a dimethoxytrityl (DMT) protecting group, which facilitates efficient incorporation and subsequent deprotection during synthesis. This reagent enables the production of fluorescently labeled oligonucleotides for applications such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays. Synonyms: 6-Fluorescein Phosphoramidite; 2-Dimethoxytrityloxymethyl-6-(3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-6-Fluorescein phosphoramidite (with DMT); Propanoic acid, 2,2-dimethyl-, 6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; DMT-6-FAM phosphoramidite. Grade: 95%. CAS No. 316121-60-5. Molecular formula: C68H78N3O13P. Mole weight: 1176.33.
6-Fluo-10-NAD?
6-Fluo-10-NAD? is a fluorescent analogue of β-NAD+ (λexc494 nm, λem517 nm) used as a non-radioactive alternative to radio-labelled β-NAD+ for research on enzymes requiring β-NAD+. Synonyms: β- Nicotinamide- N6- (2- (6- [fluoresceinyl]aminohexanoyl)aminoethyl)adenine dinucleotide, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C50H53N9O21P2 (free acid). Mole weight: 1178 (free acid).
6-Fluorescein CE Phosphoramidite
6-Fluorescein CE Phosphoramidite, a fluorescent tagging reagent utilized in the synthesis of nucleoside modifications for oligonucleotide labeling, boasts high quantum yield and fluorescence stability. Biomedical research yields various applications for this reagent, specifically including DNA sequencing, genotyping, and PCR analysis. Fluorescent labeling additionally assists in drug discovery research for identifying and characterizing candidates. With its ability to support real-time PCR, microarray analysis, and gene expression, this flexible reagent remains an indispensable tool for scientists seeking to enhance their experimental outcomes. Grade: >95% by HPLC. Molecular formula: C67H76N3O14P. Mole weight: 1178.33.
6-Fluorescein dT phosphoramidite
6-Fluorescein dT phosphoramidite can be inserted into the desired sequence as a replacement for a dT residue during oligonucleotides synthesis. Synonyms: Uridine, 5-[3-[[6-[[[3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]amino]hexyl]amino]-3-oxo-1-propen-1-yl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityloxy-5-[N-((3',6'-dipivaloylfluoresceinyl)-aminohexyl)-3-acrylimido]-2'-deoxyuridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Fluorescein-dT Phosphoramidite; Fluorescein dT CEP; 6-FAM-dT Phosphoramidite. Grade: ≥95%. CAS No. 1194507-30-6. Molecular formula: C79H89N6O17P. Mole weight: 1425.56.
6-Fluorescein phosphoramidite
6-Fluorescein phosphoramidite is prepared from 6-carboxyfluorescein derivatives and does not contain 4,4'-dimethoxytrityl (DMT) groups. It can only be added once at the 5'end to terminate the synthesis. Synonyms: FAM Phosphoramidite, 6-Isomer; 6-FAM phosphoramidite; FAM phosphoramidite, 6-isomer; DyLight FAM-6 CEP; 5'(6)-FAM; 5'-6-Fluorescein phosphoramidite; 6-((6-(((2-Cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate). Grade: ≥90%. CAS No. 204697-37-0. Molecular formula: C46H58N3O10P. Mole weight: 843.94.
6-Fluorescein Serinol Phosphoramidite
6-Fluorescein Serinol Phosphoramidite, a high-potency biocompatible fluorescent probe, finds extensive application in bioconjugation and labeling strategies for DNA and RNA synthesis. With its lucid capability to detect DNA and RNA oligonucleotides in fluorescence microscopy experiments, it has become a quintessential tool for hybridization assays. Its immense potential in modern biological research has termed it as a breakthrough innovation in the field of biochemistry and biophysics. Synonyms: 3-Dimethoxytrityloxy-2-(3-(6-carboxy-(di-O-pivaloyl-fluorescein)propanamido)propyl)-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1,5-dioxo-9,11-dioxa-2,6-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[7-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1,5-dioxo-9,11-dioxa-2,6-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate). CAS No. 1275574-87-2. Molecular formula: C67H75N4O14P. Mole weight: 1191.30.
6-Fluoro-1-(5-fluoro-2-pyridinyl)-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid is an analogue of Fandofloxacin, which is an oral difluoroquinolone antibacterial. Synonyms: 3-Quinolinecarboxylic acid, 6-fluoro-1-(5-fluoro-2-pyridinyl)-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-; 6-Fluoro-1-(5-fluoropyridin-2-yl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid. CAS No. 164151-00-2. Molecular formula: C20H18F2N4O3. Mole weight: 400.38.
6-Fluoro-3-indolyl b-D-galactopyranoside
6-Fluoro-3-indolyl b-D-galactopyranoside, a highly esteemed compound within the biomedical industry, serves as an invaluable asset for various scientific endeavors. Its paramount role lies in its utilization as a substrate for the enzyme β-galactosidase, enabling profound advancements in gene expression analysis and protein localization studies. Synonyms: Rouge-gal; 6-Fluoro-3-indoxyl b-D-galactoside; 6-Fluoro-1H-indol-3-yl β-D-galactopyranoside; (2S,3R,4S,5R,6R)-2-((6-Fluoro-1H-indol-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 6-Fluoro-3-indolyl-β-D-galactopyranoside. CAS No. 207727-11-5. Molecular formula: C14H16FNO6. Mole weight: 313.28.
6-Fluoro-6-deoxy-D-glucopyranose
6-Fluoro-6-deoxy-D-glucopyranose is a biomedical product widely used in the treatment of various diseases. It serves as a crucial component in the synthesis of antiviral drugs, specifically targeting influenza viruses. Synonyms: 6-Deoxy-6-fluoro-glucopyranose; Glucose 6-Fluorohydrin; 6-Fluoro-6-deoxy-glucopyranose; (3R,4S,5S,6S)-6-(Fluoromethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol. Grade: ≥95%. CAS No. 447-25-6. Molecular formula: C6H11FO5. Mole weight: 182.15.
6-Formamidopenicillanic Acid is a penicillin related compound. Synonyms: [2S-(2α,5α,6β)]-6-(formylamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; Hypericum; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(formylamino)-3,3-dimethyl-7-oxo-, (2S,5R,6R)-; 6-Formamido-2,2-dimethylpenam-3α-carboxylic acid. Grade: 98%. CAS No. 64527-04-4. Molecular formula: C9H12N2O4S. Mole weight: 244.27.
6-Formylpterin
6-Formylpterin is a pteridine derivative that acts as a xanthine oxidase inhibitor. Synonyms: Pterin-6-aldehyde; 2-Amino-4-hydroxy-6-formylpteridine. Grade: 95%. CAS No. 712-30-1. Molecular formula: C7H5N5O2. Mole weight: 191.15.
6-Fu-ADP
6-Fu-ADP is a precursor of the corresponding radio-labelled triphosphate that can be used for studies on kinase-substrate relationships (chemical genetics approach). Grade: ≥ 95% by HPLC. Molecular formula: C15H19N5O11P2 (free acid). Mole weight: 507.3 (free acid).
6-Fu-ATP
6-Fu-ATP is an analogue of ATP used to specifically interact with modified receptor proteins (chemical genetics approach). Synonyms: N6- Furfuryladenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1450894-16-2. Molecular formula: C15H20N5O14P3 (free acid). Mole weight: 587.3 (free acid).
6-Fu-ATP-γ-S
6-Fu-ATP-γ-S is an analogue used to specifically interact with modified receptor proteins (chemical genetics approach). Synonyms: N6- Furfuryladenosine- 5'- O- (3- thiotriphosphate), sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1400539-83-4. Molecular formula: C15H20N5O13P3S (free acid). Mole weight: 603.3 (free acid).
6'-Fucosyllactose
6'-Fucosyllactose, an indispensable compound in the realm of biomedicine, has garnered considerable attention due to its profound therapeutic capabilities. By virtue of its remarkable capacity to modulate the gastrointestinal microbiota, it exhibits encouraging prospects in mitigating afflictions besieging the gastrointestinal tract and curtailing susceptibility to infections. Furthermore, its hypothesized immunomodulatory properties may offer viable avenues for the management and prophylaxis of specific maladies. Synonyms: Fuc(a1-6)Gal(b1-4)aldehydo-Glc; 6-Deoxy-alpha-L-galacto-hexopyranosyl-(1->6)-beta-D-galacto-hexopyranosyl-(1->4)-aldehydo-D-gluco-hexose; O-6-Deoxy-α-L-galactopyranosyl-(1→6)-O-β-D-galactopyranosyl-(1→4)-D-glucose; 6'-O-α-L-Fucopyranosyllactose; 6'-O-α-L-Fucosyllactose; (2R,3R,4R,5R)-2,3,5,6-Tetrahydroxy-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-((((2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal. Grade: 95%. CAS No. 80756-86-1. Molecular formula: C18H32O15. Mole weight: 488.44.
6-(Furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is a highly efficacious antiviral compound, finding significant utility within the biomedical sphere for research of viral infections. By impeding viral replication and dissemination, it attenuates the deleterious manifestations associated with these infections. Synonyms: 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(furan-2-yl)purine; (2R,3S,4S,5R)-4-Fluoro-2-(6-(furan-2-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol; 9H-Purine, 9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furanyl)-. Grade: ≥95%. CAS No. 1612191-89-5. Molecular formula: C14H13FN4O4. Mole weight: 320.28.
6-(Furan-2-yl)purine-beta-D-riboside
6-(Furan-2-yl)purine-beta-D-riboside is an indispensable compound compound, exhibiting inhibitory potential in the research of diverse ailments such as leukemia and cancer. Synonyms: 9-(β-D-Ribofuranosyl)-6-(furan-2-yl)purine; 9-(beta-D-Ribofuranosyl)-6-(2-furyl)-9H-purine; (2R,3R,4S,5R)-2-[6-(2-furyl)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 352025-81-1. Molecular formula: C14H14N4O5. Mole weight: 318.28.
6'-Galactosyllactose
β6'-Galactosyllactose is a carbohydrate compound with applications as a prebiotic to promote the growth of beneficial gut bacteria. Synonyms: Galb1-6Galb1-4Glc; D-Glucose, O-β-D-galactopyranosyl-(1→6)-O-β-D-galactopyranosyl-(1→4)-; alpha-D-GLCP-(1->6)-alpha-D-GLCP-(1->4)-D-GLCP; O-β-D-Galactopyranosyl-(1→6)-O-β-D-galactopyranosyl-(1→4)-D-glucose; β6'-Galactosyllactose; β-6'-D-Galactosyllactose. Grade: 95%. CAS No. 32581-31-0. Molecular formula: C18H32O16. Mole weight: 504.43.
6-Gingerdiol
6-Gingerdiol is a naturally occurring compound sourced from ginger, widely utilized in the biomedical sector. Renowned for its anti-inflammatory attributes, this compound demonstrates considerable potential for studying an array of ailments, including cancer and cardiovascular maladies. Grade: > 95%. CAS No. 53318-09-5. Molecular formula: C17H28O4. Mole weight: 296.41.
6-Gingerdione
6-Gingerdione is a powerful compound derived from ginger, possessing remarkable anti-inflammatory and anticancer attributes. Renowned for its exceptional bioactivity, this molecule exhibits significant efficacy in studying a diverse range of ailments, encompassing cancer , arthritis and neurodegenerative afflictions. Synonyms: Gingerdione; [6]-Gingerdione; 1-(4-Hydroxy-3-methoxyphenyl)-3,5-decanedione; 3,5-Decanedione, 1-(4-hydroxy-3-methoxyphenyl)-; 4,7-Dichloro-Benzo(b)thiophen-3(2h)-one; 3,5-Decadione, 1-(4-hydroxy-3-methoxyphenyl). Grade: >95%(Mixture of Tautomeric Isomers). CAS No. 61871-71-4. Molecular formula: C17H24O4. Mole weight: 292.30.
6'-GNTI dihydrochloride
6'-GNTI dihydrochloride is a potent and selective κ/δ-opioid heterodimer receptor agonist (EC50 = 39.8, 112.5 and > 1000 nM for κ/δ, κ/μ and δ/μ, respectively) without effecting on opioid receptor homodimers (EC50 > 1000 nM). 6'-GNTI exhibits tissue-specific analgesic effects in vitro. Synonyms: 6''-Guanidinyl-17-(cyclopropylmethyl)-6,7-dehydro-4,5a-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinan dihydrochloride. Grade: ≥97% by HPLC. Molecular formula: C27H29N5O3.2HCl. Mole weight: 544.48.
6H05
6H05 is a selective inhibitor of oncogenic mutant K-Ras(G12C) without affecting wild-type K-Ras. Synonyms: 1-[2-(4-chlorophenyl)sulfanylacetyl]-N-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide6H051469338-01-9GTPL8023s7330ZINC205778612CS-3429; CS 3429; CS3429BC600592HY-12408; HY 12408; HY124081-{2-[(4-chlorophenyl)sulfanyl]acetyl}-N-(2-{[2-(dimethylamino)ethyl]disulf. CAS No. 1469338-01-9. Molecular formula: C20H30ClN3O2S3. Mole weight: 476.12.
6H05 TFA
6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C). Synonyms: 6H05 trifluoroacetate; 6H05 (trifluoroacetate); 2061344-88-3; 6H05 (TFA); 6H05 TFA; 1-[2-(4-chlorophenyl)sulfanylacetyl]-N-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]piperidine-4-carboxamide; 2,2,2-trifluoroacetic acid; s7330; HMS3653E14; 1469338-01-9(free base); HY-12408A; AKOS026750271; CCG-270161; CS-3428; MS-30517; FT-0742955; SW219399-1; F85070; 1-(2-((4-chlorophenyl)thio)acetyl)-n-(2-((2-(dimethylamino)ethyl)dithio)ethyl)-4-piperidinecarboxamide 2,2,2-trifluoroacetate. Grade: ≥97%. CAS No. 2061344-88-3. Molecular formula: C20H30ClN3O2S3·CF3COOH. Mole weight: 590.14.
6-Hexachloro-Fluorescein Phosphoramidite
6-Hexachloro-Fluorescein Phosphoramidite is a fluorescent dye used for oligonucleotide labeling. Synonyms: HEX phosphoramidite, 6-isomer; DyLight HEX CEP; 6-(4,7,2',4',5',7'-Hexachloro-3',6'-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[10-[Bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); Hex-C6-amidite. Grade: ≥95%. CAS No. 1360547-55-2. Molecular formula: C46H52N3O10Cl6P. Mole weight: 1050.61.
6-Hexadecanoate-β-D-fructofuranosyl-α-D-glucopyranoside, a carbohydrate molecule with potential anti-diabetic properties, has been found to significantly reduce blood glucose levels and improve insulin sensitivity in animal studies. Its promising therapeutic potential for the treatment of diabetes and related metabolic disorders warrants further research and development. Synonyms: Sucrose, 6-palmitate; Sucrosepalmitate; ((2R,3S,4S,5R,6R)-6-(((2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl palmitate; α-D-Glucopyranoside, β-D-fructofuranosyl, 6-hexadecanoate; Palmitic acid, 6-ester with sucrose; 6-O-Palmitoylsucrose; Ryoto Sugar Ester P 1695. CAS No. 13039-41-3. Molecular formula: C28H52O12. Mole weight: 580.71.
It is a specific fluorescent substrate for galactosidase in the diagnosis of Krabb's disease. Synonyms: 6-HMU galactoside; N-[7-(β-D-Galactopyranosyloxy)-4-methyl-2-oxo-2H-1-benzopyran-6-yl]-hexadecanamide; HMGal. Grade: ≥95%. CAS No. 94452-17-2. Molecular formula: C32H49NO9. Mole weight: 591.73.
6-Hexanoylamino-4-methylumbelliferyl b-D-galactopyranoside is an imperative compound that is indispensable in the realm of detecting and investigating diverse β-galactosidase enzymes. Functioning as a fluorogenic substrate, it seamlessly facilitates the discernment and scrutiny of said enzymes that frequently intertwine with an array of genetic afflictions and ailments. Synonyms: N-[7-(β-D-Galactopyranosyloxy)-4-methyl-2-oxo-2H-1-benzopyran-6-yl]hexanamide. Molecular formula: C22H29NO9. Mole weight: 451.47.
KP372-1 is a specific Akt inhibitor that demonstrates at least 10-fold selectivity against a panel of additional kinase targets, including CDK1, ERK1, GSK3β, LCK, MEK1, PKA, PKC, and S6K. It blocks Akt signalling through the PI3K pathway, and inhibits cell proliferation while inducing apoptosis of thyroid cancer cells. Synonyms: 6H-Indeno[1,2-e]tetrazolo[1,5-b][1,2,4]triazin-6-one. Grade: ≥95%. CAS No. 1374996-60-7. Molecular formula: C20H8N12O2. Mole weight: 448.4.
HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. Synonyms: 6H-Purin-6-one, 2-amino-9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-, [1R-(1α,2β,3β,4α)]-; 2-Amino-9-[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-6H-purin-6-one; D-Carbocyclic-2'-deoxyguanosine. Grade: ≥98% (HPLC). CAS No. 111687-37-7. Molecular formula: C11H15N5O4. Mole weight: 281.27.
6H-Purin-6-one, 2-amino-9-[(1S,2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hex-2-yl]-1,9-dihydro- is an incredible chemical compound of great interest to researchers and healthcare providers alike. Its potential as a therapeutic for a vast array of medical conditions is undeniable, with its immunosuppressive qualities rendering it particularly useful in treating autoimmune disorders. Furthermore, studies have shown that it can be effective in treating viral infections such as hepatitis B and C, and even certain types of malignancies. The intricate structure of this molecule must be meticulously studied in order to fully grasp its potential applications in the field of biomedicine. CAS No. 374593-66-5. Molecular formula: C12H15N5O4. Mole weight: 293.28.
6H-Purin-6-one, 2-amino-9-[(2R)-2,5-dihydro-5,5-bis(hydroxymethyl)-2-furanyl]-1,9-dihydro, known for its intricate molecular composition, is a remarkably efficacious antiviral compound extensively employed in the biomedical realm. Its distinctive architecture bestows it with momentous proficiency against a wide array of viral variants, primarily for research of entrenched viral maladies such as hepatitis B and C. CAS No. 1238972-34-3. Molecular formula: C11H13N5O4. Mole weight: 279.25.
An effective inhibitior of ERK5, could probably be used as an antitumor agent. IC50: 0.19μM(EC50 for cellular),of 0.087 μM(for enzymatic) and 0.087 μM(for LRRK2). Uses: An effective inhibitior of erk5 and could probably be used as an antitumor agent. Synonyms: ERK5-IN-1; ERK5 IN 1; ERK5IN1; CHEMBL1673039; SCHEMBL618262; BDBM50337127; ZINC66066276; CS-4938; HY-14403. Grade: 98%. CAS No. 1234479-76-5. Molecular formula: C25H29N7O2. Mole weight: 459.54.
6-HT-cGMP
6-HT-cGMP, a cyclic guanosine monophosphate (cGMP) analog, has been subject to extensive research as a prospective therapy for cardiovascular ailments. With vasoconstriction being a leading cause of such diseases, extensive studies have shown that 6-HT-cGMP act as a vasodilator. Animal models have indicated that it can increase coronary blood flow, giving it potential clinical implications. Furthermore, 6-HT-cGMP is promising in the treatment of erectile dysfunction. A comprehensive understanding of its properties and mechanisms is imperative as it shows great potential in treating these prevalent conditions. Synonyms: 6- Hexylthioguanosine- 3', 5'- cyclic monophosphate. Molecular formula: C16H23N5O6PS · Na. Mole weight: 467.4.
6-Hydroxy-4-isobutyl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile is an intriguing compound embraced by the biomedical industry, holding immense promise in research of an array of diseases. Synonyms: 3,5-Pyridinedicarbonitrile, 1,2-dihydro-6-hydroxy-4-(2-methylpropyl)-2-oxo-; 6-Hydroxy-4-isobutyl-2-oxo-1,2-dihydro-3,5-pyridinedicarbonitrile. Grade: ≥95%. CAS No. 861318-48-1. Molecular formula: C11H11N3O2. Mole weight: 217.22.
6-Hydroxy-5-methoxy-1-indanone
An impurity of Donepezil, a medication for the treatment of Alzheimer's disease. Uses: 6-hydroxy-5-methoxy-1-indanone (cas# 90843-62-2) is a compound useful in organic synthesis. Synonyms: 6-hydroxy-5-methoxy-2,3-dihydroinden-1-one; 6-hydroxy-5-methoxy-2,3-dihydroinden-1-one. CAS No. 90843-62-2. Molecular formula: C10H10O3. Mole weight: 178.18.
6-Hydroxy Alosetron
A derivative of Alosetron. Synonyms: 2,3,4,5-Tetrahydro-6-hydroxy-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; 2,3,4,5-Tetrahydro-6-hydroxy-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; 6-Hydroxy Lotronex. Grade: > 95%. CAS No. 128486-89-5. Molecular formula: C17H18N4O2. HCl. Mole weight: 310.36.
6-Hydroxy Bexarotene
6-Hydroxy Bexarotene is a metabolite of Bexarotene. Synonyms: 4-[1-(5,6,7,8-Tetrahydro-6-hydroxy-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid. Grade: > 95%. CAS No. 368451-07-4. Molecular formula: C24H28O3. Mole weight: 364.49.
6-Hydroxy Buspirone
a major active metabolite of Buspirone. Synonyms: 6-Hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9- dione; 6'-Hydroxybuspirone. Grade: > 95%. CAS No. 125481-61-0. Molecular formula: C21H31N5O3. Mole weight: 401.51.
6-Hydroxybuspirone hydrochloride
A major active metabolite of Buspirone, a 5-HT1A partial agonist, with higher bioavailability than that of buspirone. Synonyms: BMS 528215 hydrochloride; 6OHB; 6-OH-Bu; 6-hydroxy-8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro[4.5]decane-7,9-dione hydrochloride. Grade: 98%. CAS No. 2108825-99-4. Molecular formula: C21H31N5O3.HCl. Mole weight: 437.96.
6-Hydroxy Chlorzoxazone
A major metabolite of chlorzoxazone. Formed by the actions of cytochrome P450IIE1. Synonyms: 5-Chloro-6-hydroxy-2(3H)-benzoxazolone; 6-Hydroxychlorzoxazone; NSC 24955. Grade: > 95%. CAS No. 1750-45-4. Molecular formula: C7H4ClNO3. Mole weight: 185.57.
6-Hydroxy Coumarin
6-Hydroxy Coumarin is a noteworthy biomedical entity manifesting indispensable potential in the research of diverse afflictions encompassing cancer and cardiovascular disorders. Synonyms: 2H-1-Benzopyran-2-one, 6-hydroxy-; 6-hydroxy-2H-1-Benzopyran-2-one. Grade: >98%. CAS No. 6093-68-1. Molecular formula: C9H6O3. Mole weight: 162.14.
6-Hydroxycytidine
6-Hydroxycytidine is a remarkable nucleoside analog with potent antiviral properties, emerging as a prospective compound in the research of various viral strains encompassing coronaviruses, influenza viruses and even the notorious hepatitis C virus. Its mode of action entails the inhibition of viral RNA research and development. CAS No. 15477-67-5. Molecular formula: C9H13N3O6. Mole weight: 259.22.
6-Hydroxy Desloratadine
6-Hydroxy Desloratadine is a hydroxylated metabolite of Desloratadine. Synonyms: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)- 5H-benzo[5,6]cyclohepta[1,2-b]pyridin-6-ol; Sch 39090. Grade: > 95%. CAS No. 119410-05-8. Molecular formula: C19H19ClN2O. Mole weight: 326.82.
6-Hydroxy Dexamethasone (Mixture of Diastereomers)
6-Hydroxy Dexamethasone (Mixture of Diastereomers) is an impurity of Desoxymetasone which is an anti-inflammatory agent. Molecular formula: C22H29FO6. Mole weight: 408.46.