BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
L-Lysine is a nutritional supplement containing the biologically active L-isomer of the essential amino acid lysine, with potential anti-mucositis activity. Upon oral intake, L-lysine promotes healthy tissue function, growth and healing and improves the immune system. L-Lysine promotes calcium uptake, is essential for carnitine production and collagen formation. As collagen is essential for connective tissue maintenance, this agent may also help heal mucosal wounds. This may help decrease and prevent mucositis induced by radiation or chemotherapy. Synonyms: L-Lys-OH H2O; (S)-2,6-Diaminohexanoic acid monohydrate; L-Lysine monohydrate; Lysine monohydrate; L(+)-Lysine monohydrate; L-Lysine, hydrate; (2S)-2,6-diaminohexanoic acid hydrate; L Lys OH H2O. Grades: ≥ 99% (Titration). CAS No. 39665-12-8. Molecular formula: C6H14N2O2·H2O. Mole weight: 164.20.
L-Lysine methyl ester dihydrochloride
Used in the synthesis of peptides containing histidine and lysine. Synonyms: L-Lys-OMe 2HCl; DL-lysine methyl ester dihydrochloride; L-2,6-diaminohexanoic acid methyl ester dihydrochloride; LysOMe dihydrochloride; L-Lysine methyl ester 2HCl; H-Lys-OMe 2HCl. Grades: ≥ 99% (HPLC). CAS No. 26348-70-9. Molecular formula: C7H16N2O2·2HCl. Mole weight: 233.10.
LL-Z 1220 is a natural antibiotic which contains a cyclohexene diepoxide ring system. Synonyms: Antibiotic LL-Z 1220; 2-[(1r,2r,4r,7r)-3,8-dioxatricyclo[5.1.0.02,4]oct-5-en-5-yl]-4h-pyran-4-one; (1alpha,2beta,4beta,7alpha)-(-)-2-(3,8-Dioxatricyclo(5.1.0.0(2,4))oct-5-en-5-yl)-4H-pyran-4-one. CAS No. 36431-52-4. Molecular formula: C11H8O4. Mole weight: 204.18.
LL Z1640-2
LL Z1640-2 is a macrolide antibiotic produced by the strain of Deuteromyces sp. It is an irreversible and highly selective TAK 1 inhibitor and a member of the MAPKKK family that activates JNK/p38 and NF-κB pro-inflammatory signaling pathways. It effectively prevents inflammation in animal models. LL Z1640-2 is a covalent inhibitor that acts against the several protein kinases (e.g. ERK2 and TAK1) which possess a free cysteine at the gatekeeper-2 position. Synonyms: C292; L 783278; Antibiotic LL Z1640-2; (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; (-)-LL-Z 1640-2; (5Z)-7-Oxozeaenol; (Z)-7-Oxozeaenol; C 292; F 152; f 152 A1; FR 148083; LL-Z 1640-2. Grades: >99% by HPLC. CAS No. 253863-19-3. Molecular formula: C19H22O7. Mole weight: 362.37.
LL Z1640-4
A cis-enol resorcylic acid lactone exhibiting antiviral and antiprotozoan activity. Synonyms: Zeaenol. Grades: >99% by HPLC. CAS No. 66018-41-5. Molecular formula: C19H24O7. Mole weight: 364.39.
L-Methionine methyl ester is a protected form of L-Methionine. L-Methionine is an essential amino acid that is obtained from our diet. L-Methionine can be found in grain legumes (such as lentils), and poultry. L-Methionine's main function is to act as the primary start sequence on mRNA so that the ribosomes can start translating the mRNA into proteins. Synonyms: L-Met-OMe HCl; H-Met-OMeCl; H-Met-Ome HCl; H-MET-OME HCl; Met-OMe HCl; L-methionine methyl ester hydrochloride salt. Grades: 98-102% (Assay). CAS No. 2491-18-1. Molecular formula: C6H13NO2S·HCl. Mole weight: 199.70.
L-Methionine-(S,R)-sulfoximine is an inhibitor of glutamine synthetase and a sulfoximine derivative of L-methionine. Synonyms: L-Methionine Sulfoximine. CAS No. 15985-39-4. Molecular formula: C5H12N2O3S. Mole weight: 180.23.
L-Methionine Sulfone is an impurity of L-Methionine which is an essential amino acid for human development. L-Methionine is a hepatoprotectant, an antidote (acetominophen poisoning) and a urinary acidifier. Synonyms: L-Met(O2)-OH; L-2-Amino-4-(methylsulfonyl)butanoic acid; methionine sulfone; L-METHIONINE SULFONE. Grades: ≥ 98% (Titration). CAS No. 7314-32-1. Molecular formula: C5H11NO4S. Mole weight: 181.20.
L-Methionine sulfoxide
An intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine. Synonyms: L-Met(O)-OH; L-2-Amino-4-(methylsulfoxyl)butanoic acid; (2S)-2-Amino-4-(methylsulfinyl)butanoic acid; L-2-Amino-4-(methylsulfinyl)butanoic acid; L-METHIONINE SULFOXIDE. Grades: ≥ 99% (HPLC). CAS No. 3226-65-1. Molecular formula: C5H11NO3S. Mole weight: 165.20.
L-Methionine tert-butyl ester hydrochloride
L-Methionine tert-butyl ester is a protected form of L-Methionine. L-Methionine is an essential amino acid that is obtained from our diet. L-Methionine can be found in grain legumes (such as lentils), and poultry. L-Methionine's main function is to act as the primary start sequence on mRNA so that the ribosomes can start translating the mRNA into proteins. Synonyms: L-Met-OtBu HCl; (S)-tert-Butyl 2-amino-4-(methylthio)butanoate hydrochloride; tert-butyl(2S)-2-amino-4-methylsulfanylbutanoate hydrochloride. Grades: ≥ 99% (HPLC). CAS No. 91183-71-0. Molecular formula: C9H19NO2S·HCl. Mole weight: 241.73.
L-Norleucine
L-Norleucine, an isomer of leucine, specifically affects skeletal muscle protein synthesis and has antiviral activity. Uses: A non-essential amino acid. used as internal standard in amino acid analysis. Synonyms: Norleucine, L-; (S)-2-Aminohexanoic acid; (S)-Norleucine; (S)-α-Aminohexanoic acid; 2-Aminocaproic acid; L-(+)-Norleucine; L-2-Aminohexanoic acid; Caprine; Glycoleucine; Hexanoic acid, 2-amino-, (S)-; Norleucine; NSC 10378; NSC 74430; α-Aminocaproic acid. Grades: ≥97%. CAS No. 327-57-1. Molecular formula: C6H13NO2. Mole weight: 131.18.
It is produced by the strain of Streptomyces argenteolus A-2. Longestin inhibited Ca2+ and CAM-PDE in bovine brain with an IC50 of 0.065 μmol/L. Synonyms: KS-505a; 2-((6-carboxy-4, 5-dihydroxy-3-methoxytetrahydro-2H-pyran-2-yl)oxy)-14-hydroxy-8a, 10a-bis(hydroxymethyl)-14-(3-methoxy-3-oxopropyl)-1, 4, 4a, 6, 6a, 17b, 19b, 21b-octamethyl-16-oxo-2, 3, 4, 4a, 4b, 5, 6, 6a, 6b, 7, 8, 8a, 8b, 9, 10, 10a, 14, 16, 17, 17a, 17b, 18, 19, 19a, 19b, 20, 21, 21a, 21b, 22, 23, 23a-dotriacontahydro-1H-benzo[9, 10]piceno[3, 4-a]furo[3, 4-j]xanthene-1-carboxylic acid. CAS No. 131774-53-3. Molecular formula: C61H88O17. Mole weight: 1093.34.
LONG R3 IGF-1 (human)
LONG R3 IGF-1 (human) is a recombinant analog of human insulin-like growth factor-I (IGF-I). Synonyms: long R3 igf-I. CAS No. 143045-27-6. Molecular formula: C400H619N111O115S9. Mole weight: 9111.45.
It is produced by the strain of Str. WK-4028. In the presence of 10-7 mol/L testosterone, it can significantly inhibit the growth of SC115 cells (IC50 is 0.6 μg/mL). It has no inhibitory effect on testosterone 5α-reductase, and it has no anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast effects. Synonyms: Louisianine A; 4-allyl-6,7-dihydro-1H-cyclopenta[c]pyridine-1,5(2H)-dione. CAS No. 171784-03-5. Molecular formula: C11H11NO2. Mole weight: 189.21.
Lovastatin (Mevinolin)
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent). Uses: Antioxidant / antihypercholesterolemic / antiarrhythmic. Synonyms: Mevacor; Monacolin K; Altoprev; MK 803; MK-803; MK803; Monacolin K; QAB149; MSD 803; Simvastatin EP Impurity E; Simvastatin USP Related Compound E; Desmethyl Simvastatin. Grades: >98%. CAS No. 75330-75-5. Molecular formula: C24H36O5. Mole weight: 404.54.
L-PHE(4-COCH3)
Synonyms: L-Phe(4-Ac)-OH; L-4-Acetylphe. Grades: ≥ 98% by Chiral HPLC. CAS No. 122555-04-8. Molecular formula: C11H13NO3. Mole weight: 207.23.
L-Phenylalanine 4-nitroanilide
A substrate for aminopeptidase M (microsomal alanyl aminopeptidase). Synonyms: L-Phe-pNA; L-phenylalanine N-(4-nitrophenyl)amide; H-Phe-pNA; L-phenylalanine p-nitroanilide; (S)-2-Amino-N-(4-nitrophenyl)-3-phenylpropanamide. Grades: ≥ 99% (HPLC). CAS No. 2360-97-6. Molecular formula: C15H15N3O3. Mole weight: 285.30.
L-Phenylalanine allyl ester 4-toluenesulfonate salt
L-Phenylalanine benzyl ester hydrochloride is a commonly used reactant for the synthesis of L-isoserine derivatives as aminopeptidase N inhibitors and PF-04449913 as a potent and orally bioavailable inhibitor of smoothened. Synonyms: L-Phe-OBzl HCl; H-L-Phe-Obzl HCl; H-Phe-OBn hydrochloride; PHE-OBZL HCl; H-Phe-OBzl HCl; L-Phenylalanine Benzyl Ester Hydrochloride. Grades: ≥ 99% (HPLC). CAS No. 2462-32-0. Molecular formula: C16H17NO2·HCl. Mole weight: 291.80.
L-Phenylalanine b-naphthylamide
A substrate for aminopeptidase M (microsomal alanyl aminopeptidase). Synonyms: L-Phe-bNA; L-Phenylalanine-B-Naphthylamide; N-L-Phenylalanyl-2-naphthylamin; L-Phenylalanine-Naphthylamide; L-Phenylalanin-[2]naphthylamid. Grades: ≥ 99% (TLC). CAS No. 740-57-8. Molecular formula: C19H18N2O. Mole weight: 290.32.
L-Phenylalanine chloromethylketone hydrochloride
An inhibitor of gramicidin S synthetase 2. Synonyms: L-Phenylalanine chloromethylketone hydrochloride; PHENYLALANINE-CHLOROMETHYLKETONE HCl; L-PHENYLALANINE CHLOROMETHYLKETONE HYDROCHLORIDE; H-PHE-CHLOROMETHYLKETONE HCl; H-PHE-CMK HCl. Grades: ≥ 99% (NMR). CAS No. 52735-71-4. Molecular formula: C10H12NOCl·HCl. Mole weight: 234.19.
Substrate for human kidney prolinase (prolyl dipeptidase). Synonyms: Pro-Ala-OH; Pro Ala OH. Grades: ≥ 99% (TLC). CAS No. 6422-36-2. Molecular formula: C8H14N2O3. Mole weight: 186.21.
L-Propargylglycine
It is produced by the strain of Streptomyces sp. It can inactivate many vitamin B6-enzymes, such as Cystathionine γ-synthase, Methionone γ-lyase and L-alanine aminotransferase. Synonyms: (S)-2-Aminopent-4-ynoic acid; (S)-2-Amino-4-pentynoic acid; L-2-Propynylglycine; (S)-Propargylglycine; (S)-2-Propargylglycine; L-Pra-OH; L-Propargyl-Gly-OH; 4-Pentynoic acid, 2-amino-, (2S)-; (2S)-2-Amino-4-pentynoic acid; 4-Pentynoic acid, 2-amino-, (S)-; 4-Pentynoic acid, 2-amino-, L-; (2S)-2-Azaniumylpent-4-ynoate; (S)-α-Propargylglycine; L-2-Amino-4-pentynoic acid. Grades: ≥95%. CAS No. 23235-01-0. Molecular formula: C5H7NO2. Mole weight: 113.11.
L-Serine 1,1-Dimethylethyl Ester Hydrochloride is used in the synthesis of diabetes type 2 inhibitors. Also used in the synthesis of bifunctional and trifunctional chelating agents. Synonyms: L-Ser-OtBu HCl; L-β-Hydroxyalanine tert-butyl ester hydrochloride; (S)-tert-Butyl 2-amino-3-hydroxypropanoate hydrochloride; tert-butyl(2S)-2-amino-3-hydroxypropanoate hydrochloride. Grades: ≥ 99% (TLC). CAS No. 106402-41-9. Molecular formula: C7H15O3N·HCl. Mole weight: 197.62.
L-Threonine Amide Hydrochloride is used as a reagent in the synthesis of N-monosubstituted [(pyridin-2-yl)methyl]amine and [(pyrimidin-4-yl)methyl]amine derivatives as transient receptor potential cation channel 3 (TRPV3) modulators. Synonyms: L-Thr-NH2 HCl; H-Thr-NH2 HCl; 2-Amino-3-hydroxy-(2S,3R)butanamide monohydrochloride; L-Threoninamide hydrochloride. Grades: ≥ 98%(HPLC). CAS No. 33209-01-7. Molecular formula: C4H10N2O2·HCl. Mole weight: 154.60.