BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
L-Aspartic acid 4-methyl ester is a protected form of L-Aspartic acid. L-Aspartic acid is a non-essential amino acid that is used to biosynthesize other amino acids within the human body. L-Aspartic acid also increases membrane conductance of mammalian neurons by voltage-dependent means, causing depolarization and nerve impulses that travel to key areas of the central nervous system. Synonyms: L-Aspartic acid, 4-methyl ester, hydrochloride (1:1); L-Aspartic acid, 4-methyl ester, hydrochloride; Aspartic acid, 4-methyl ester, hydrochloride, L-; (S)-2-Amino-4-methoxy-4-oxobutanoic acid hydrochloride; L-Aspartic acid β-methyl ester monohydrochloride; β-Methyl L-aspartate hydrochloride. Grades: ≥95%. CAS No. 16856-13-6. Molecular formula: C5H9NO4.HCl. Mole weight: 183.59.
L-Aspartic acid 4-tert-butyl ester is a protected form of L-Aspartic acid. L-Aspartic acid is a non-essential amino acid that is used to biosynthesize other amino acids within the human body. L-Aspartic acid also increases membrane conductance of mammalian neurons by voltage-dependent means, causing depolarization and nerve impulses that travel to key areas of the central nervous system. Synonyms: L-Aspartic acid β-tert-butyl ester; L-aspartic acid 4-tert-butyl ester; (2S)-2-amino-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid. Grades: ≥ 98% (Assay). CAS No. 3057-74-7. Molecular formula: C8H15NO4. Mole weight: 189.20.
L-Aspartic acid dibenzyl ester 4-toluenesulfonate salt
L-Aspartic acid dibenzyl ester p-toluenesulfonate salt is used in the preparation of Betulinic acid derivatives that show inhibition towards HIV. It is also used in the preparation of piperidine functional amides which act as potent and highly selective human β3 agonists. Synonyms: L-Asp(OBzl)-OBzl TosOH; L-aspartic acid dibenzyl ester p-toluenesulfonate salt; H-Asp(OBzl)-OBzl Tos-OH; 1,4-Dibenzyl L-Aspartate p-Toluenesulfonate; L-Aspartic Acid 1,4-Dibenzyl Ester p-Toluenesulfonate. Grades: ≥ 99% (HPLC). CAS No. 2886-33-1. Molecular formula: C18H19NO4·C7H8O3S. Mole weight: 485.60.
An unusual heterocyclic metabolite isolated from fusarium avenaceum with antibacterial and antifungal activity. Synonyms: Avenacein Y. Grades: >99% by HPLC. CAS No. 93752-78-4. Molecular formula: C15H10O8. Mole weight: 318.23.
Lavanducyanin
Lavanducyanin is a testosterone 5 alpha-reductase inhibitor isolated from Streptomyces sp. No. 9659. It exhibits weak activity against gram-positive bacteria. Synonyms: WS-9659 A; WS-9659A; WS 9659 A. CAS No. 122228-60-8. Molecular formula: C22H24N2O. Mole weight: 332.4.
Lavendamycin
It is produced by the strain of Str. lavendulae C-22030. It's a quinone antibiotic. It has anti-bacterial and fungal effect, but the anti-bacterial effect is weaker than Streptonigrin, while the anti-fungal effect is stronger than Streptonigrin. Synonyms: 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl-; Antibiotic K 82A. CAS No. 81645-09-2. Molecular formula: C22H14N4O4. Mole weight: 398.38.
Lavendomycin
It is produced by the strain of Str. lavendulae subsp. brasillicus. It has strong activity against Staphylococcus aureus, Staphylococcus epidermococcus and Streptococcus faecalis with ED50 (mg/kg) of 2.33, 1.68 and 13.2, respectively (In vivo test in mice, abdominal infection, subcutaneous administration). It has no anti-gram-negative bacteria and fungi activity. Synonyms: Antibiotic FR 900201; ( (Z) -2- ( (S) -1- ( (S) -1- ( (2S, 3R) -3-amino-2- ( (2S, 3R) -2-amino-5-guanidino-3-methylpentanamido) butanoyl) piperidine-2-carbonyl) pyrrolidine-2-carboxamido) but-2-enoyl) -L-serine. Grades: ≥95%. CAS No. 82987-09-5. Molecular formula: C29H50N10O8. Mole weight: 666.78.
It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Synonyms: Antibiotic A-130A; A-130A; Antibiotic Ro 21 6150; Dianemycin, 10-demethyl-19-de[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, [11(2R,5S,6R),12R]-; 6-Nonenoic acid, 8-[2,4',10,10'-tetramethyl-2'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy][2,7'-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-, [2S-[2a[2'S*, 4'R*, 5'S*, 7'S*[2R*, 5S*, 7R*(2R*, 4S*, 6E, 8R*), 9S*(2S*, 5R*, 6S*), 10S*], 10'S*], 3b, 5b, 6b]]-. CAS No. 51257-84-2. Molecular formula: C47H78O13. Mole weight: 851.11.
Lenoremycin sodium
It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Synonyms: Antibiotic A130 sodium salt; Dianemycin, 10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, monosodium salt, (11(2R,5S,6R),12R)-; Antibiotic A-130A Sodium salt. CAS No. 58399-44-3. Molecular formula: C47H77NaO13. Mole weight: 873.10.
Leptocillin
Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Synonyms: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34.
Leptofuranin A
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72.
Leptofuranin B
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75.
Leptofuranin C
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70.
Leptofuranin D
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73.
Leptolstatin
It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Synonyms: 2H-Pyran-2-one, 6-[(1E, 3Z, 5R, 7E, 9E, 11R, 13S, 14R, 15S, 17E)-14, 19-dihydroxy-3, 5, 9, 11, 13, 15, 17-heptamethyl-12-oxo-1, 3, 7, 9, 17-nonadecapentaen-1-yl]-5, 6-dihydro-, (6R)-; (R)-6-((1E, 3Z, 5R, 7E, 9E, 11R, 13S, 14R, 15S, 17E)-14, 19-dihydroxy-3, 5, 9, 11, 13, 15, 17-heptamethyl-12-oxononadeca-1, 3, 7, 9, 17-pentaen-1-yl)-5, 6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69.
Leptomycin A
a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Synonyms: Jildamycin; Antibiotic ATS 1287A; Antibiotic PD 118607; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-. Grades: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C32H46O6. Mole weight: 526.71.
Leptosin I
It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18, 22a-(Iminomethano)-10b, 23a-methano-10bH, 23aH-indolo[2'', 3'':2', 3'][1, 2, 3, 4, 6]tetrathiazocino[6'', 5'':1', 5']pyrrolo[3', 4':6, 7]pyrazino[2''', 1''':2, 3][1, 3]oxazepino[4, 5-b]indole-1, 4, 17, 25(18H)-tetrone, 2, 3, 5a, 6, 15, 15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2, 26-dimethyl-18-(1-methylethyl)-, (3a, 5ab, 10ba, 10cS*, 15ab, 18b, 22ab, 22ba, 23aa, 24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leptosin J
It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18, 22a-(Iminomethano)-10b, 23a-methano-10bH, 23aH-indolo[2'', 3'':2', 3'][1, 2, 3, 4, 6]tetrathiazocino[6'', 5'':1', 5']pyrrolo[3', 4':6, 7]pyrazino[2''', 1''':2, 3][1, 3]oxazepino[4, 5-b]indole-1, 4, 17, 25(18H)-tetrone, 2, 3, 5a, 6, 15, 15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2, 26-dimethyl-18-(1-methylethyl)-, (3a, 5aa, 10bb, 10cR*, 15aa, 18a, 22aa, 22bb, 23ab, 24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
L-Ethionine
Ethionine is an antimetabolite and methionine antagonist. It also produces liver neoplasms. Uses: Ethionine-induced inhibition of protein synthesis and lowering of atp level in the liver. Synonyms: H-Eth-OH; (S)-2-Amino-4-(ethylthio)butanoic acid. Grades: 98%. CAS No. 13073-35-3. Molecular formula: C6H13NO2S. Mole weight: 163.24.
Leu-Ala-OH
This dipeptide inhibits ubiquitin-mediated protein degradation. Synonyms: L-Leucyl-L-alanine. Grades: ≥ 97% (HPLC). CAS No. 7298-84-2. Molecular formula: C9H18N2O3. Mole weight: 202.25.
Leucanicidin
It is produced by the strain of Streptomyces. It is a potent nematocide and insecticide belonging to the bafilomycin class. It also has anti-fungal properties. Synonyms: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(6-deoxy-2-O-methyl-α-L-mannopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one; 21-O-De(3-carboxy-1-oxo-2-propenyl)-2-demethyl-21-O-(6-deoxy-2-O-methyl-α-L-mannopyranosyl)-2-methoxy-24-methylhygrolidin. Grades: >95% by HPLC. CAS No. 91021-66-8. Molecular formula: C42H70O13. Mole weight: 783.00.
It is produced by the strain of Paecilomyces lilacinus A-267. It's a peptide antibiotic. It has a strong anti-pathogenic and non-pathogenic yeast and fungi activity, but also has a medium anti-bacterial effect. It was previously reported that Leucinostatin A and B mixtures inhibited HeLa cells. 0.05 μg/mL of Leucinostatin A for a week (0.25 mg/kg?d) has inhibitory effect on the airy ascites carcinoma entity type, and for ascites type is invalid. Synonyms: Antibiotic 1907-VIII; Antibiotic CC 1014; Paecilotoxin A; Antibiotic P-168; beta-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-(2-(dimethylamino)-1-methylethyl)-, (1(S-(E)),9(S))-; Tryanocidin. Grades: >95% by HPLC. CAS No. 76600-38-9. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Leucinostatin B
It is produced by the strain of Paecilomyces lilacinus A-267. It's a peptide antibiotic. It has a strong anti-pathogenic and non-pathogenic yeast and fungi activity, but also has a medium anti-bacterial effect. It was previously reported that Leucinostatin A and B mixtures inhibited HeLa cells. 0.05 μg/mL of Leucinostatin B for a week (0.25 mg/kg?d) has inhibitory effect on the airy ascites carcinoma entity type, and for ascites type is invalid. Synonyms: Paecilotoxin B; Leucinostatin A, 9-[N-[1-methyl-2-(methylamino)ethyl]-b-alaninamide]-, [9(S)]-; Antibiotic 1907-II; b-Alaninamide, cis-4-methyl-1-(4-methyl-1-oxo-2-hexenyl)-L-prolyl-(4S,6S)-6-hydroxy-4-methyl-8-oxo-L-2-aminodecanoyl-threo-3-hydroxy-L-leucyl-2-methylalanyl-L-leucyl-L-leucyl-2-methylalanyl-2-methylalanyl-N-[1-methyl-2-(methylamino)ethyl]-, [1[S-(E)],9(S)]-. Grades: >95%. CAS No. 76663-52-0. Molecular formula: C61H109N11O13. Mole weight: 1204.58.
Leucinostatin D
It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. It has in vitro cytotoxic activity against HeLa 850, KB cells and sensitive leukemia cells P388 with ID50 of 1.00 ng/mL. Synonyms: Paecilotoxin D; (4R) -N- [1- [ [2-hydroxy-3-methyl-1- [2- [ [3-methyl-1- [ [3-methyl-1- [2- [2- [2- (1-methylaminopropan-2-ylcarbamoyl) ethylcarbamoyl] propan-2-ylcarbamoyl] propan-2-ylcarbamoyl] butyl] carbamoyl] butyl] carbamoyl] propan-2-ylcarbamoyl] butyl] carbamoyl] -3-methyl-butyl] -4-methyl-1- [ (E, 4S) -4-methylhex-2-enoyl] pyrrolidine-2-carboxamide. CAS No. 100334-47-2. Molecular formula: C56H101N11O11. Mole weight: 1104.47.
Leucinostatin H
It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. Synonyms: Paecilotoxin H; N-(1-(aminooxy)-26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28-octaoxo-5,9,12,15,18,21,24,27-octaazadotriacontan-29-yl)-4-methyl-1-((R,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide; Leucinostatin A, 2-L-leucine, N9-oxide. CAS No. 109539-58-4. Molecular formula: C57H103N11O12. Mole weight: 1134.49.