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| Product | Description | |
|---|---|---|
| Kibdelin A | Kibdelin A is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin A is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-50-3. Molecular formula: C81H84Cl4N8O29. Mole weight: 1775.38. |  |
| Kibdelin B | Kibdelin B is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin B is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-49-0. Molecular formula: C82H86Cl4N8O29. Mole weight: 1789.41. | |
| Kibdelin C1 | Kibdelin C1 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C1 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((10-methyl-1-oxoundecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103549-47-9. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43. | |
| Kibdelin C2 | Kibdelin C2 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C2 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-85-1. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43. | |
| Kibdelin D | Kibdelin D is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin D is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Synonyms: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-86-2. Molecular formula: C81H82Cl4N8O29. Mole weight: 1773.36. | |
| Kibdelone A | It is a potent antitumour metabolite isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. It's cytotoxic. Synonyms: (10S,12S,13R)-4-Chloro-10,11,12,13-tetrahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-77-4. Molecular formula: C29H24ClNO10. Mole weight: 581.96. | |
| Kibdelone B | It is a minor analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10R,12R,13S)-rel-(+)-4-Chloro-6,7,10,11,12,13-hexahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-78-5. Molecular formula: C29H26ClNO10. Mole weight: 583.97. | |
| Kibdelone C | It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Synonyms: (10S,12S,13R)-4-Chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione; (+)-Kibdelone C. Grades: >95% by HPLC. CAS No. 934464-79-6. Molecular formula: C29H28ClNO10. Mole weight: 585.99. | |
| Kigamicin A | Kigamicin A is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C34H35NO13. Mole weight: 665.64. | |
| Kigamicin B | Kigamicin B is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C40H45NO15. Mole weight: 779.78. | |
| Kigamicin C | Selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions; active in vivo against a human pancreatic cancer xenograft model; also inhibits the growth of gram positive bacteria including MRSA, but is not active against gram negative bacteria. Synonyms: (1S, 3R, 4S, 8aR, 11aR)-3-[[(2S, 5S, 6R)-5-[(2, 6-dideoxy-3-O-methyl-b-D-arabinohexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1, 2, 3, 4, 8a, 9, 11, 11a, 13, 14-decahydro-1, 4, 17, 18-tetrahydroxy-11a-methyl-oxazolo[3, 2-b]xantheno[4', 3', 2':4, 5][1, 3]benzodioxino[7, 6-g]isoquinoline-16, 19-dione. Grades: >98% by HPLC. CAS No. 680571-51-1. Molecular formula: C41H47NO16. Mole weight: 809.81. | |
| Kigamicin D | Kigamicin D is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. It also shows effect against L-1210 LB32T and other genera tumor cells with IC50 of 1 μg/mL. Synonyms: 1,2,3a,4,6,7,10,11,12,13-Decahydro-11-[[5-[[5-[(tetrahydro-5-hydroxy-4-methoxy-6-methyl-2H-pyran-2-yl)oxy]tetrahydro-4-methoxy-6-methyl-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-10,13,15,16-tetrahydroxy-3a-methyl-7,8-(methylenedioxy)-17a-aza-3,9-dioxa-17aH-cyclopenta[b]hexaphene-14,17-dione. Molecular formula: C48H59NO19. Mole weight: 953.98. | |
| Kijanimicin | A tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin; contains an unusual nitroaminoglycoside; a potent antibacterial, antimalarial and antitumour active; inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). Synonyms: NSC 329515; Sch 25663. Grades: >99% by HPLC. CAS No. 78798-08-0. Molecular formula: C67H100N2O24. Mole weight: 1317.51. | |
| Kinamycin A | Kinamycin A is produced by the strain of Str. murayamaensis. Kinamycin A has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Synonyms: BRN 0505520; 2,3,4-Tri(acetyloxy)-1,2,3,4,6,11-hexahydro-1,7-dihydroxy-3-methyl-6,11-dioxo-5H-benzo(b)carbazole-5-nitrile; 1,2,3-Tris(acetyloxy)-11-diazonio-4,9-dihydroxy-2-methyl-10-oxo-2,3,4,10-tetrahydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-12-9. Molecular formula: C24H20N2O10. Mole weight: 496.42. | |
| Kinamycin B | Kinamycin B is produced by the strain of Str. murayamaensis. Kinamycin B has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Synonyms: BRN 0503790; (1R,2R,3R,4S)-2-acetyloxy-11-diazonio-1,3,4,10-tetrahydroxy-2-methyl-9-oxo-3,4-dihydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-13-0. Molecular formula: C20H16N2O8. Mole weight: 412.35. | |
| Kirromycin | Kirromycin is an antibiotic originally isolated from Streptomyces. It was shown to inhibit protein biosynthesis via acting on elongation factor Tu (EF-Tu). Synonyms: Mocimycin; Delvomycin. Grades: ≥95%. CAS No. 50935-71-2. Molecular formula: C43H60N2O12. Mole weight: 796.94. | |
| Kistamicin A | Kistamicin A is produced by the strain of Microtetraspora parvasata subsp. kistna. It has antiviral effect, and its ID50 (μg/mL) against influenza virus MDCK cells and herpes simplex virus are respectively 3.6 and 44. It also has anti-gram-positive bacterial effects. Synonyms: Kistamycin A. CAS No. 155683-50-4. Molecular formula: C61H51ClN8O15. Mole weight: 1171.55. | |
| Kistamicin B | Kistamicin B is produced by the strain of Microtetraspora parvasata subsp. kistna. It has antiviral effect, and its ID50 (μg/mL) against influenza virus MDCK cells and herpes simplex virus are respectively 1.8 and 30. Synonyms: Kistamycin B. CAS No. 155683-51-5. Molecular formula: C70H60ClN9O16. Mole weight: 1318.73. | |
| Kitamycin A | It is originally isolated from Strptomyces sp. K385. Kitamycin A can inhibit the activity of plant growth. Molecular formula: C23H32N2O8. Mole weight: 464.51. | |
| Kodaistatin A | Kodaistatin A is originally isolated from Asperrgilus terreus Thom DSM 11237. It inhibits the glucose-6-phosphotransferase T1 (G-6-P-T1) with the IC50 of 80 nmol/L. Molecular formula: C35H34O11. Mole weight: 630.64. | |
| Kodaistatin C | Kodaistatin B is originally isolated from Asperrgilus terreus Thom DSM 11237. It inhibits the glucose-6-phosphotransferase T1 (G-6-P-T1) with the IC50 of 130 nmol/L. Synonyms: Kodaistatin B. Molecular formula: C35H34O12. Mole weight: 646.64. | |
| Korormicin | It has the effect of resisting Marine gram-negative bacteria, but not against the marine gram-positive bacteria and general bacteria. Synonyms: (3R,4Z,6E)-N-[(5S)-5-Ethyl-5-methyl-2-oxo-2,5-dihydro-3-furanyl]-3-hydroxy-8-[(2S,3R)-3-octyl-2-oxiranyl]-4,6-octadienamid. Molecular formula: C25H39NO5. Mole weight: 433.58. | |
| Kosinostatin | Kosinostatin is originally isolated from Paecilomyces sp. FO-3184. It showed strong anti-gram-positive bacterial activity (MIC of 0.039 μg/mL) and moderate anti-gram-negative bacterial and yeast activity (MIC of 1.56-12.5 μg/mL). It is also poisonous to the cells of a wide variety of tumor cells with the IC50 of 0.02-0.6 μmol/L. And the IC50 of inhibition of DNA topoisomerase IIα is 3-10 μmol/L. Synonyms: Isoquinocycline B. Molecular formula: C33H32N2O10. Mole weight: 616.61. | |
| KS-501 | It is produced by the strain of Sporothrix sp. KAC-1989. KS-501 inhibited Ca2+ and calmodulin dependent cyclic-nucleotide phosphodiesterase with an IC50 of 1.8 μmol/L. Synonyms: KS 501; 3-Heptyl-5-hydroxyphenyl 2-heptyl-6-(hexofuranosyloxy)-4-hydroxybenzoate. CAS No. 120634-86-8. Molecular formula: C33H48O10. Mole weight: 604.73. | |
| KS 502 | It is produced by the strain of Sporothrix sp. KAC-1989. KS 502 inhibited Ca2+ and calmodulin dependent cyclic-nucleotide phosphodiesterase with an IC50 of 4.4 μmol/L. Synonyms: Benzoic acid, 2-(beta-D-galactofuranosyloxy)-6-heptyl-4-hydroxy-, 4-carboxy-3-heptyl-5-hydroxyphenyl ester. Grades: >98%. CAS No. 120634-85-7. Molecular formula: C34H48O12. Mole weight: 648.74. | |
| KS 504a | It is produced by the strain of Mollisia ventosa KAC-1148. KS 504a inhibited Ca2+ and calmodulin dependent cyclic-nucleotide phosphodiesterase with an IC50 of 122 μmol/L. Synonyms: KS-504a; KS-504b; BRN 4354490; 1-Oxaspiro(2.4)heptan-5-ol, 2,4,4,6,6-pentachloro-7-(dichloromethylene)-. CAS No. 122022-77-9. Molecular formula: C7H3Cl7O2. Mole weight: 367.27. | |
| KS-504d | It is produced by the strain of Mollisia ventosa KAC-1148. KS-504d inhibited Ca2+ and calmodulin dependent cyclic-nucleotide phosphodiesterase with an IC50 of >500 μmol/L. Synonyms: KS 504d; BRN 4322179; (+)-1-(Dichloromethyl)-5-(dichloromethylene)-2,2,4,4-tetrachloro-1,3-cyclopentanediol. CAS No. 122005-23-6. Molecular formula: C7H4Cl8O2. Mole weight: 403.73. | |
| KS-504e | It is produced by the strain of Mollisia ventosa KAC-1148. KS-504e inhibited Ca2+ and calmodulin dependent cyclic-nucleotide phosphodiesterase with an IC50 of 139 μmol/L. Synonyms: KS 504e; BRN 4321107; (+)-4-Hydroxy-3,3,5,5-tetrachloro-2-(trichloromethyl)-1-cyclopentene-1-carboxaldehyde; 1-Cyclopentene-1-carboxaldehyde, 3,3,5,5-tetrachloro-4-hydroxy-2-(trichloromethyl)-, (+)-. CAS No. 122006-32-0. Molecular formula: C7H3Cl7O2. Mole weight: 367.27. | |
| KS-619-1 | It is produced by the strain of Streptomyces californicus KS-619-1. KS-619-1 inhibited Ca2+ and CAM-PDE in bovine brain and heart with an IC50 of 2.0 and 1.5 μmol/L. Synonyms: KS 619-1; Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-1,7,9,11-tetrahydroxy-8,13-dioxo-3-(2-oxopropyl)-. CAS No. 103370-21-4. Molecular formula: C26H18O9. Mole weight: 474.41. | |
| KT5720 | KT 5720, an anti-bacterial agent synthesized by the fungus Nocardiopsis sp, specifically blocks PKA signaling through competitive inhibition of ATP with a Ki value of 60 nM. Uses: Anti-bacterial agents. Synonyms: 2,3,9,10,11,12-hexahydro-10S-hydroxy-9-methyl-1-oxo-9R,12S-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester; KT 5720; KT5720; KT-5720. Grades: 98%. CAS No. 108068-98-0. Molecular formula: C32H31N3O5. Mole weight: 537.60. | |
| KT5823 | KT 5823 is a cell-permeable, selective inhibitor of cGMP-dependent protein kinase (PKG) (Ki values are 0.23, 4 and > 10 μM for inhibition of PKG, PKC and PKA respectively). KT 5823 is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells. Uses: Kt5823 induces apoptotic fragmentation of dna. Synonyms: KT 5823; KT-5823; KT5823; 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9S,12R-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester. Grades: ≥98%. CAS No. 126643-37-6. Molecular formula: C29H25N3O5. Mole weight: 495.52. | |
| Kumbicin C | Kumbicin C is a bis-indolyl benzenoid fungal metabolite produced by A. kumbius FRR6049. Kumbicin C was found to inhibit the growth of mouse myeloma cells (IC50 = 0.74 μg/mL) and the Gram-positive bacterium Bacillus subtilis (MIC = 1.6 μg/mL). Synonyms: 5,8-di-1H-indol-3-yl-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-ol. Grades: ≥95%. CAS No. 1878151-58-6. Molecular formula: C28H24N2O3. Mole weight: 436.50. | |
| Kurasoin A | It is produced by the strain of Paecilomyces sp. FO-3184, Kurasoin A has the effect of inhibiting the protein fannicyl transferase. Synonyms: (+)-Kurasoin A; (S)-3-Hydroxy-4-(4-hydroxyphenyl)-1-phenyl-2-butanone. CAS No. 182232-62-8. Molecular formula: C16H16O3. Mole weight: 256.30. | |
| Kurasoin B | It is produced by the strain of Paecilomyces sp. FO-3184, Kurasoin B has the effect of inhibiting the protein fannicyl transferase. Synonyms: (+)-Kurasoin B. Molecular formula: C18H17NO2. Mole weight: 279.33. | |
| Kynapcin-12 | It is produced by the strain of Polyozellus multiplex. It has the activity of inhibiting proline endopeptidase (PEP, EC 3.4.21.26) with IC50 of 1.25 μg/mL. Synonyms: kynapcin 12. Molecular formula: C22H18O8. Mole weight: 410.37. | |
| Kynapcin-13 | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 76.80 μmol/L. It has a little inhibitory effect on other serine proteases. Synonyms: kynapcin 13. Molecular formula: C12H10O7. Mole weight: 266.20. | |
| Kynapcin-28 | It is produced by the strain of Polyozellus multiplex. It can non-competitively inhibit the activity of PEP with IC50 of 0.98 μmol/L. It has little inhibitory effect on other serine proteases. Synonyms: kynapcin 28. Molecular formula: C19H12O10. Mole weight: 400.29. | |
| L-156602 | L-156602 is extracted from Streptomyces sp. MA6348, and it is the antagonist of Anaphylatoxin C5a. It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria. Synonyms: Antibiotic L 156602; Antibiotic PD-124966; GNF-Pf-75; L 156602; PD-124966; (3S)-3-hydroxy-N-[(2S)-2-hydroxy-1-oxo-2-[(2R,5R,6R)-tetrahydro-2-hydroxy-6-methyl-5-[(2S)-2-methylbutyl]-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-L-alanylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-D-alanine, (6?13)-lactone. Grades: >95% by HPLC. CAS No. 125228-51-5. Molecular formula: C38H64N8O13. Mole weight: 840.96. | |
| L-2,3-Diaminopropionic acid hydrochloride | Synonyms: L-Dap-OH HCl; (S)-2,3-Diaminopropionic acid hydrochloride. Grades: ≥ 98% (Assay by titration). CAS No. 1482-97-9. Molecular formula: C3H8N2O2·HCl. Mole weight: 140.60. | |
| L-2,4-Diaminobutyric acid dihydrochloride | . Uses: A pharmacological tool and potential chiral building block. it is also used as an internal standard for amino acid analysis. also found to inhibit gaba transaminase, thus producing an elevation of gaba level, and to have an antitumor activity in vitro a. Synonyms: L-Dab-OH 2HCl; (S)-2,4-Diaminobutyric acid dihydrochloride. Grades: ≥ 98% (HPLC). CAS No. 1883-09-6. Molecular formula: C4H10N2O2·2HCl. Mole weight: 191.14. | |
| L-2,4-Dichlorophenylalanine | Synonyms: L-Phe(2,4-DiCl)-OH; H-L-Phe(2,4-Cl2)-OH; (S)-2-Amino-3-(2,4-dichlorophenyl)propionic acid. Grades: ≥ 99% (HPLC). CAS No. 111119-36-9. Molecular formula: C9H9NO2Cl2. Mole weight: 234.20. | |
| L-2,4-Dimethylphe | Grades: 98%. CAS No. 259726-65-2. Molecular formula: C11H15NO2. Mole weight: 193.24. | |
| L-2,4-Dinitrophenylalanine | Synonyms: H-Phe{2,4-(NO2)2}-OH; L-2,4-Dinitrophe. Grades: ≥ 99% (HPLC). CAS No. 49607-21-8. Molecular formula: C9H9N3O6. Mole weight: 255.18. | |
| L-2,5-Dihydrophenylalanine | It is produced by the strain of Streptomyces sp. L-2,5-Dihydrophenylalanine can cause apoptosis of HL-60 in human myeloblastoid leukemia cells. Synonyms: 2,5-Dihydrophenylalanine; 2,5-dihydrophenyl-L-alanine; L-3-(2,5-Cyclohexadienyl)alanine. CAS No. 16055-12-2. Molecular formula: C9H13NO2. Mole weight: 167.20. | |
| L-2-Amino-4-bromo-4-pentenoic acid | Synonyms: (S)-2-Amino-4-bromo-4-pentenoic acid; (S)-2-Amino-4-bromopent-4-enoic acid; L-2-Amino-4-bromo-4-pentenoic acid; (2S)-2-amino-4-bromopent-4-enoic acid; 4-Pentenoic acid, 2-amino-4-bromo-, (S)-(9CI). Grades: ≥ 99% (HPLC, Chiral purity). CAS No. 151144-96-6. Molecular formula: C5H8BrNO2. Mole weight: 194.03. | |
| L-2-Aminomethylphenylalanine | Synonyms: L-Phe(2-CH2NH2)-OH. Grades: ≥ 99% by HPLC. CAS No. 158149-99-6. Molecular formula: C10H14N2O2. Mole weight: 194.23. | |
| L-(+)-2-Cyclohexylglycine hydrochloride | Synonyms: L-Chg-OH HCl; H-Cyclohexyl-L-Gly-OH HCl; (S)-Cyclohexylglycine hydrochloride. Grades: ≥ 99% (Titration). CAS No. 14328-51-9. Molecular formula: C8H15NO2·HCl. Mole weight: 193.70. | |
| L-2-Cyclohexylglycine tert-butyl ester hydrochloride | Synonyms: L-Chg-OtBu HCl; H-L-Cyclohexyl-Gly-OtBu HCl. Grades: ≥ 98% (Assay). CAS No. 213475-52-6. Molecular formula: C12H23NO2·HCl. Mole weight: 249.82. | |
| L-2-Hydroxybutyric acid | L-2-Hydroxybutyric acid (CAS# 3347-90-8) is used in method for preparing Cationic Electrodeposition coating compounds. Synonyms: S-2-hydroxybutyric acid. CAS No. 3347-90-8. Molecular formula: C4H8O3. Mole weight: 104.1. | |
| L-2-Hydroxyphenylalanine | . Uses: A metabolite of phenylalanine. Synonyms: L-o-Tyrosine; (S)-3-(2-Hydroxyphenyl)alanine. Grades: ≥ 98% (Chiral HPLC). CAS No. 7423-92-9. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
| L-2-Methoxyphenylalanine | Synonyms: L-Phe(2-OMe)-OHo-Methoxy-L-phenylalanine; (S)-2-Amino-3-(2-methoxyphenyl)propionic acid. Grades: ≥ 98% (Chiral HPLC). CAS No. 193546-31-5. Molecular formula: C10H13NO3. Mole weight: 195.20. | |
| L-3,4-Dichlorophenylalanine | Synonyms: L-Phe(3,4-DiCl)-OH; (S)-2-Amino-3-(3,4-dichlorophenyl)propionic acid; H-L-Phe(3,4-Cl2)-OH. Grades: ≥ 99% (HPLC). CAS No. 52794-99-7. Molecular formula: C9H9NO2Cl2. Mole weight: 234.20. | |
| L-3,5-Diiodotyrosine ethyl ester hydrochloride | Synonyms: 3,5-Diiodo-L-Tyr-OEt HCl. Grades: ≥ 97% (HPLC). CAS No. 74051-47-1. Molecular formula: C11H13NO3I2Cl. Mole weight: 496.51. | |
| L-3,5-Diiodotyrosine methyl ester hydrochloride | Synonyms: H-3,5-Diiodo-L-Tyr-OMe HCl. Grades: ≥ 98% (HPLC). CAS No. 151266-48-7. Molecular formula: C10H11NO3I2·HCl. Mole weight: 483.50. | |
| L-3-Methoxyphenylalanine | Synonyms: L-Phe(3-OMe)-OH; m-Methoxy-L-phenylalanine; (S)-2-Amino-3-(3-methoxyphenyl)propionic acid. Grades: 99%. CAS No. 33879-32-2. Molecular formula: C10H13NO3. Mole weight: 195.2. | |
| L-681176 | L-681176 is originally isolated from Streptomyces sp. MA 5143a. It has the activity of inhibiting angiotensin transferase. Synonyms: L-681,176. CAS No. 91386-17-3. Molecular formula: C12H23N5O7. Mole weight: 349.34. | |
| L-681217 | A glycolipid-type antibiotic related to the efrotomycin class; isolated from a streptomyces sp.; shows broad spectrum antibiotic activity against gram positive and gram negative bacteria. Synonyms: L 681217; Antibiotic L-681217; 2,4,6-Heptatrienoic acid, 7-(tetrahydro-3-hydroxy-5-(2-methoxy-1,3-dimethyl-7-((1-oxo-2-(tetrahydro-2,4,5-trihydroxy-5-methyl-6-(1,3-pentadienyl)-2H-pyran-2-yl)butyl)amino)-3,5-heptadienyl)-2-furanyl)-. Grades: >95% by HPLC. CAS No. 93522-10-2. Molecular formula: C36H53NO10. Mole weight: 659.80. | |
| L 687781 | L 687781, an inhibitor of β-1,3-D-glucan synthase, is originally isolated from Dictyochaeta simplex. It also has anti-Candida fungal activity and has some effects on Pneumocystis carinii. Synonyms: Hexopyranose, 1,6'-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4-decadienyl)hexopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-1-oxo-2,4,6,8,10-hexadecapentaenoate). CAS No. 130304-58-4. Molecular formula: C47H66O17. Mole weight: 903.01. | |
| L-696474 | L-696474 is extracted from Hypoxylon fragiforme MF5511. It can competitively inhibit the action of HIV-1 protease with an IC50 of 3 μmol/L. Synonyms: L-696,474; 18-dehydroxycytochalasin H. Grades: >98% by HPLC. CAS No. 141994-72-1. Molecular formula: C30H39NO4. Mole weight: 477.63. | |
| L-783277 | L-783277 is originally isolated from Phoma sp. It inhibits MEK2 with an IC50 of 4 nmol/L. Synonyms: (3S,5Z,8S,9S)-3,4,9,10,11,12-Hexahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione; LL-783277. Grades: ≥95%. CAS No. 791807-02-8. Molecular formula: C19H24O7. Mole weight: 364.39. | |
| LA-1 | LA-1 is an aliphatic unsaturated ketonic acid produced by Streptomyces kitasatoensis NU-4-4-2. It has anti-gram-positive bacteria activity. CAS No. 61947-93-1. Molecular formula: C10H10O3. Mole weight: 178.18. | |
| Labilomycin | It is produced by the strain of Str. albospoeus var. labilomyceticus A955-y3. It's a sugar antibiotic. It has anti-gram-positive bacteria, mycobacterium activity. It had cytotoxic effect on HeLa cells and Yoshida sarcoma cells. Each rat (Transplantation of airy ascites carcinoma in mice) is given Labilomycin of 250 μg/d, it can inhibit tumor and prolong life. It has a protective effect on mice infected with S. aureus. Serum does not affect its antibacterial activity. Synonyms: Pulvomycin; Oxacyclodocosa-4,7,9,11,15,17,19-heptaene-2,13-dione, 22-[(1S,2S,3S,5E,7E,9E,11S,12S)-12-[(6-deoxy-2,4-di-O-methyl-β-D-galactopyranosyl)oxy]-2,11-dihydroxy-1,3-dimethyl-4-oxo-5,7,9-tridecatrien-1-yl]-6,14-dihydroxy-5,8,12-trimethyl-, (4E, 6R, 7E, 9E, 11E, 14S, 15E, 17E, 19E, 22S)-; (4E, 6R, 7E, 9E, 11E, 14S, 15E, 17E, 19E, 22S)-22-[(1S, 2S, 3S, 5E, 7E, 9E, 11S, 12S)-12-[(6-Deoxy-2, 4-di-O-methyl-β-D-galactopyranosyl)oxy]-2, 11-dihydroxy-1, 3-dimethyl-4-oxo-5, 7, 9-tridecatrien-1-yl]-6, 14-dihydroxy-5, 8, 12-trimethyloxacyclodocosa-4, 7, 9, 11, 15, 17, 19-heptaene-2, 13-dione; (-)-Pulvomycin; Antibiotic 1063Z. CAS No. 11006-66-9. Molecular formula: C47H66O13. Mole weight: 839.02. | |
| Laccaridione A | It is produced by the strain of Laccaria amethystea. It can inhibit the activity of antiserine protease. It inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50 (μg/mL) of 14.7, 2.5, 18.8, 7.2 and 18.2, respectively. Synonyms: 10-hydroxy-1,7-dimethoxy-3-[(2E)-4-methylhex-2-en-2-yl]-1H-benzo[g]isochromene-8,9-dione; 1H-Naphtho(2,3-C)pyran-8,9-dione, 3-((1E)-1,3-dimethyl-1-penten-1-yl)-10-hydroxy-1,7-dimethoxy-. CAS No. 320369-80-0. Molecular formula: C22H24O6. Mole weight: 384.42. | |
| Laccaridione B | It is produced by the strain of Laccaria amethystea. It can inhibit the activity of antiserine protease. It inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50 (μg/mL) of 10.9, 5.1, 8.4, 5.7 and 3.0, respectively. It also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50 (μg/mL) of 2.4, 1.8 and 13.9, respectively. Synonyms: 1-ethoxy-10-hydroxy-7-methoxy-3-[(2E)-4-methylhex-2-en-2-yl]-1H-benzo[g]isochromene-8,9-dione; 1H-Naphtho[2,3-c]pyran-8,9-dione, 3-[(1E)-1,3-dimethyl-1-pentenyl]-1-ethoxy-10-hydroxy-7-methoxy-. CAS No. 320369-81-1. Molecular formula: C23H26O6. Mole weight: 398.45. | |
| Lachnone A | It is a chromone isolated from the filamentous fungus, lachnum sp. It possesses weak activity against bacteria but has not been extensively investigated. Synonyms: Lanchnone A; 3,?5-Dihydroxy-2,?7-dimethyl-4H-1-benzopyran-4-one. Grades: >95% by HPLC. CAS No. 903892-99-9. Molecular formula: C11H10O4. Mole weight: 206.19. | |
| Lachnumol A | It is produced by the strain of Lachnum papyraceum. It has weaker activity against bacteria, yeast and filamentous fungi. It has cytotoxic activity against L1210, HeLa, KB and other cell lines. Synonyms: La; 1-chloro-6-[(Z)-1-chloroprop-1-enyl]-4-methoxy-7-oxabicyclo[4.1.0]hept-3-ene-2,5-diol; 7-Oxabicyclo(4.1.0)hept-3-ene-2,5-diol, 6-chloro-1-(1-chloro-1-propenyl)-3-methoxy-. CAS No. 150671-03-7. Molecular formula: C10H12Cl2O4. Mole weight: 267.11. | |
| Lachnumon | It is produced by the strain of Lachnum papyraceum. It has weaker activity against bacteria, yeast and filamentous fungi. It has cytotoxic activity against L1210, HeLa, KB and other cell lines. Synonyms: Ln; 7-Oxabicyclo(4.1.0)hept-3-en-2-one, 1-chloro-6-(1-chloro-1-propenyl)-5-hydroxy-4-methoxy-; 6-chloro-1-[(Z)-1-chloroprop-1-enyl]-2-hydroxy-3-methoxy-7-oxabicyclo[4.1.0]hept-3-en-5-one. CAS No. 150671-02-6. Molecular formula: C10H10Cl2O4. Mole weight: 265.09. | |
| Lactaroviolin | It is produced by the strain of Lactarius deliciosus. It is an aromatic derivative antibiotic. It can inhibit the growth of Mycobacterium tuberculosis, but the effect is not strong. Synonyms: Lactarioviolin; 1-Azulenecarboxaldehyde, 4-methyl-7-(1-methylethenyl)-; 1-Formyl-7-isopropenyl-4-methylazulene; 1,3,5,7,9,11-Guaiahexaen-15-al; 7-Isopropenyl-4-methyl-1-Azulenecarboxaldehyde. CAS No. 85-33-6. Molecular formula: C15H14O. Mole weight: 210.27. | |
| Lactonamycin Z | It is produced by the strain of Streptomyces sp. AK 623. It's an antitumor antibiotic. It has weak anti-gram-positive bacterial activity. It can inhibit human tumor cells HMO2, MCF7 and Hep G2 with GI50 (μg/mL) of 1.9, 0.85 and 5.11, respectively. Molecular formula: C28H27NO13. Mole weight: 585.51. | |
| Lactoquinomycin B | It is produced by the strain of Str. tanashiensis IM 8442T. It's a quinone antibiotic. It has the activity of anti-gram-positive bacteria and some gram-negative bacteria, but the effect of anti-gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A has stronger antibacterial activity than Lactoquinomycin B. It inhibits a variety of cell lines including lymphoma L5178Y progenitor, adriamycin resistant, bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively. Synonyms: 3a,11b-Dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-β-D-arabino-hexopyranosyl]-5a,11a-epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione; 5a,11a-Epoxy-5H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11(3H)-trione, 3a,11b-dihydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-b-D-arabino-hexopyranosyl]-. CAS No. 101342-94-3. Molecular formula: C24H27NO9. Mole weight: 473.48. | |
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