BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Illudin M | Illudin M is a natural sesquiterpene agent with strong anti-tumour activity. Synonyms: (-)-Illudin M; (3'S-trans)-2',3'-Dihydro-3'b,6'a-dihydroxy-2',2',4',6'-tetramethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one; (-)-1alpha,7beta-dihydroxy-2,9-illudadien-8-one. Grades: ≥95%. CAS No. 1146-04-9. Molecular formula: C15H20O3. Mole weight: 248.32. |  |
| Inactone | Inactone is a bioactive molecule of 3-glutarimidyl group that inhibits large ribosomal subunit. CAS No. 487-34-3. Molecular formula: C15H21NO4. Mole weight: 279.33. | |
| Indanomycin | Indanomycin is an antibiotic of the pyrroloketoindane class produced by Streptomyces sp. It is an unusual pyrollic ionophore that is active against gram-positive bacteria and insects. It has antihypertensive properties. It is a growth promoter in ruminants. Synonyms: X-14547A; X 14547A; 2H-Pyran-2-acetic acid, 6-(1-ethyl-4-(1-ethyl-2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)tetrahydro-alpha, 5-dimethyl-, (1S-(1-alpha,3-alpha,beta,4-beta,5-beta(1E(2S*(S*),5R*,6S*),3E),7a-alpha))-; Antibiotic X-14547A. Grades: >95% by HPLC. CAS No. 66513-28-8. Molecular formula: C31H43NO4. Mole weight: 493.68. | |
| Indolmycin | A highly selective antibiotic which acts as a tryptophan anti-metabolite; active against mycobacteria and H. Pylori, and can stimulate transcription in escherichia coli. Synonyms: Indolemycin; PA 155 A; (-)-indolmycin; (1R,5S)-(-)-5-(1-Indol-3-ylethyl)-2-(methylamino)-2-oxazolin-4-one. Grades: >99% by HPLC (total diastereoisomers). CAS No. 21200-24-8. Molecular formula: C14H15N3O2. Mole weight: 257.29. | |
| Indomethacin Morpholinylamide | BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor. Synonyms: BML-190; BML 190; BML190; LM-4131; LM4131; LM 4131; IMMA; Indomethacin Morpholinylamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole. Grades: >98%. CAS No. 2854-32-2. Molecular formula: C23H23ClN2O4. Mole weight: 426.89. | |
| Ingenol-3-mebutate | Ingenol-3-mebutate is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death. It is effective for field treatment of actinic keratoses, significantly reduced head and non-head actinic keratosis lesions. Synonyms: PEP005; PEP-005; PEP 005; ingenol-3-angelate; Ingenol mebutate. Grades: >98%. CAS No. 75567-37-2. Molecular formula: C25H34O6. Mole weight: 430.53. | |
| Inosamycin A | Inosamycin A is a broad-spectrum antimicrobial antibiotic originally isolated from Str. hygroscopicus No. J296-21. Its antibacterial activity was comparable to that of neomycin, and about twice that of ribomycin. Synonyms: Bu 2659A; 6-Amino-2-{[3-O- (2, 6-diamino-2, 6-dideoxyhexopyranosyl) pentofuranosyl]oxy}-3, 4-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxyhexopyranoside. CAS No. 91421-97-5. Molecular formula: C23H45N5O14. Mole weight: 615.63. | |
| Inosamycin B | Inosamycin B is a broad-spectrum antimicrobial antibiotic originally isolated from Str. hygroscopicus No. J296-21. Its antibacterial activity is about half that of Inosamycin A. Synonyms: Bu 2659B; BMY-28163; 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-3-amino-2,3-dideoxy-D-myo-inositol. CAS No. 91465-52-0. Molecular formula: C23H45N5O14. Mole weight: 615.63. | |
| Ionomycin | Ionomycin is a selective calcium ionophore antibiotic isolated from Streptomyces species. Anti-Gram-positive activity. Synonyms: 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2'R, 5S, 5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2, 5'-dimethyl[2, 2'-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic acid; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, [2S-[2α[2'S*, 5'R*(S*)], 5β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-; [2S-[2α[2'S*, 5'R*(S*)], 5β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2, 5'-dimethyl[2, 2'-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic acid; SQ 23377; EM 94. Grades: >98% by HPLC. CAS No. 56092-81-0. Molecular formula: C41H72O9. Mole weight: 709.00. | |
| Ionomycin Calcium Salt | The Calcium Salt of Ionomycin, a kind of polyether antibiotic, is a selective calcium ionophore obtained from Streptomyces conglobatus by solvent extraction. It is more effective than A23187 as a calcium ionophore. It is used to study the transport of calcium ions on biological membranes. It can induce apoptotic degeneration of embryonic cortical neurons. Synonyms: Calcium ionophore; Calcium Ionomycin; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2'R, 5S, 5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2, 5'-dimethyl[2, 2'-bifuran]-5-yl]-9-oxo-10, 16-Docosadienoic Acid Calcium Salt; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, calcium salt (1:1), (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-; Ionomycin, calcium salt (1:1). Grades: ≥98%. CAS No. 56092-82-1. Molecular formula: C41H70O9Ca. Mole weight: 747.07. | |
| Iromycin A | It is produced by the strain of Streptomyces sp. NK26588. Iromycin A is a bacterial pyridone metabolite that acts as a nitric oxide synthase (NOS) inhibitor with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS). Synonyms: NK 26588; Antibiotic NK 26588; 2(1H)-Pyridinone, 6-[(2E,5E)-3,7-dimethyl-2,5-octadien-1-yl]-4-hydroxy-3-methyl-5-propyl-. Grades: ≥98%. CAS No. 213137-53-2. Molecular formula: C19H29NO2. Mole weight: 303.44. | |
| Isariin B | Isariin B is originally isolated from Isaria felina. Synonyms: 19-hexyl-6-methyl-9-(2-methylpropyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10,13,16-pentaazacyclononadecane-2,5,8,11,14,17-hexone. CAS No. 80111-95-1. Molecular formula: C30H53N5O7. Mole weight: 595.77. | |
| Isoaltenuene | Isoaltenuene is isolated from the solid cultures of the fungus Colletotrichum sp, and it shows antibacterial activity against gram-positive bacteria and exhibits cytotoxic activity against sevral cancer cells. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2α,3β,4aα)-; 6H-Dibenzo[b,d]pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2R,3R,4aS)-rel-; rel-(2R,3R,4aS)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one; (2α,3β,4aα)-(±)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grades: 97.5%. CAS No. 126671-80-5. Molecular formula: C15H16O6. Mole weight: 292.28. | |
| Isoapoptolidin | It is a ring expanded isomer of apoptolidin originally isolated from Nocardiopsis sp. It demonstrates 10-fold reduced F1FO-ATP synthase inhibitory activity compared to apoptolidin (IC50s = 17 and 0.7 μM, respectively). Synonyms: (3E, 5E, 7E, 9R, 10R, 11E, 13E, 17S, 18S, 20S, 21R)-10-[(6-Deoxy-4-O-methyl-α-L-glucopyranosyl)oxy]-21-[O-2, 6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1?4)-O-2, 6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1?7)-2, 4, 6-trideoxy-1-C-hydroxy-2, 4-dimethyl-8-O-methyl-L-glycero-β-D-galacto-octopyranosyl]-17, 20-dihydroxy-18-methoxy-3, 5, 7, 9, 13-pentamethyloxacycloheneicosa-3, 5, 7, 11, 13-pentaen-2-one; Isoapoptolidin A. Grades: >90% by HPLC. CAS No. 476647-30-0. Molecular formula: C58H96O21. Mole weight: 1129.38. | |
| Isobutyl 1,2-dihydro-2-isobutoxy-1-quinolinecarboxylate | Synonyms: IIDQ; 1-Isobutoxycarbonyl-2-isobutoxy-1,2-dihydroquinoline; 2-Isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline; Isobutyl 2-isobutoxyquinoline-1(2H)-carboxylate. Grades: 95% (HPLC). CAS No. 38428-14-7. Mole weight: 303.40. | |
| Isochlortetracycline | A metabolite of chlortetracycline, a tetracycline antibiotic. Synonyms: Isoaureomycin; 7-Chloroisotetracycline. Grades: 98%. CAS No. 514-53-4. Molecular formula: C22H23ClN2O8. Mole weight: 478.88. | |
| Isochromophilone III | Isochromophilone III is produced by the strain of Pen. multicolor FO-3216 and FO-2328. It inhibited the ACAT of rat hepatocellular microsome and the B-16 melanoma cell with the IC50 (μmol/L) of 110 and 33. Synonyms: 6H-2-Benzopyran-6-one, 5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-1,7,8,8a-tetrahydro-7,8-dihydroxy-7-methyl. CAS No. 167173-89-9. Molecular formula: C19H25ClO4. Mole weight: 352.85. | |
| Isochromophilone IV | Isochromophilone IV is produced by the strain of Pen. multicolor FO-3216 and FO-2328. It inhibited the ACAT of rat hepatocellular microsome with the IC50 (μmol/L) of 50. Synonyms: 6H-2-Benzopyran-6-one, 5-(acetyloxy)-5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-1,7,8,8a-tetrahydro-7-hydroxy-7-methyl; 3-[(1E,3E,5S)-3,5-Dimethyl-1,3-heptadienyl]-5-chloro-7-methyl-7alpha-hydroxy-8alpha-acetoxy-1,7,8,8aalpha-tetrahydro-6H-2-benzopyran-6-one. Grades: >98%. CAS No. 167173-90-2. Molecular formula: C21H27ClO5. Mole weight: 394.89. | |
| Isochromophilone V | Isochromophilone III is produced by the strain of Pen. multicolor FO-3216 and FO-2328. It inhibited the ACAT of rat hepatocellular microsome and the B-16 melanoma cell with the IC50 (μmol/L) of 50 and 36. Synonyms: 6H-2-Benzopyran-6-one, 5-chloro-3-(3,5-dimethyl-1,3-heptadienyl)-7,8-dihydro-7,8-dihydroxy-7-methyl. Grades: >98%. CAS No. 167355-56-8. Molecular formula: C19H23ClO4. Mole weight: 350.84. | |
| Isocycloheximide | It is produced by the strain of Str. griseus. Isocycloheximide has antifungal effect, and its activity to Barbiturates is only 30% of that of actinomyces. Synonyms: D-Isocycloheximide; Caswell No. 504C; (+)-3-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; Aktidion. CAS No. 6746-42-5. Molecular formula: C15H23NO4. Mole weight: 281.35. | |
| Isohematinic acid | It is produced by the strain of Actinoplanes philippinensis SANK 61681. Isohematinic acid has weak anti-anaerobic bacteria action. Synonyms: (+-)-2,5-Dioxo-4-methylene-3-pyrrolidinepropanoic acid; 3-(5-Hydroxy-4-methylidene-2-oxo-3,4-dihydro-2H-pyrrol-3-yl)propanoic acid. CAS No. 86408-37-9. Molecular formula: C8H9NO4. Mole weight: 183.16. | |
| Isoquinocycline A | Isoquinocycline A is originally isolated from Str. aureofaciens. It has strong anti-mycobacterium activity. Molecular formula: C33H34N2O10. Mole weight: 618.63. | |
| Isosativenediol | Isosativenediol is produced from the culture filtrates of a Bipolaris species pathogenic to Johnson grass. Synonyms: 2,4-Methano-1H-indene-3,8-diol, octahydro-7a-methyl-1-methylene-5-(1-methylethyl)-, (2R,3R,3aR,4R,5S,7aS,8R)-rel-(-)-; 2,4-Methano-1H-indene-1,3-diol, octahydro-4-methyl-8-methylene-7-(1-methylethyl)-, (1α, 2α, 3β, 3aβ, 4α, 7α, 7aβ)-(-)-. Grades: 98.5%. CAS No. 57079-92-2. Molecular formula: C15H24O2. Mole weight: 236.35. | |
| Isosulfazecin | Isosulfazecin is a beta-lactam antibiotic produced by the strain of Pseudomonas mesoacidophila sp. nov. Its anti-gram-positive bacteria effect is similar to SZ (Sulfazecin), but its anti-gram-negative bacteria activity is weaker than SZ. Synonyms: (R)-D-gamma-Glutamyl-N-(3-methoxy-2-oxo-1-sulfo-3-azetidinyl)-L-alaninamide; (3R) -2-Oxo-3-methoxy-3beta- [ [N- [ (4R) -4-amino-4-carboxybutyryl] alanyl] amino] azetidine-1-sulfonic acid. Grades: >98%. CAS No. 77900-75-5. Molecular formula: C12H20N4O9S. Mole weight: 396.38. | |
| Istamycin A | Istamycin A is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: Sannamycin A; Antibiotic KA 7038I; L-chiro-Inositol, 4-amino-1-((aminoacetyl)methylamino)-3-O-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-1,4,5-trideoxy-6-O-methyl-. CAS No. 72503-79-8. Molecular formula: C17H35N5O5. Mole weight: 389.49. | |
| Istamycin B | Istamycin B is produced by the strain of Str. tenjimariensis S5-939. It has strong anti-gram positive and negative bacteria action, and Istamycin B has stronger antibacterial activity than A. Synonyms: L-chiro-Inositol, 4-amino-1-(2-amino-N-methylacetamido)-3-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-beta-D-lyxo-hexopyranosyl)-6-O-methyl-1,4,5-trideoxy-. CAS No. 72523-64-9. Molecular formula: C17H35N5O5. Mole weight: 389.49. | |
| IT-143-A | IT-143-A is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Synonyms: IT-143A. Molecular formula: C29H43NO4. Mole weight: 469.65. | |
| IT-143-B | IT-143-B is produced by the strain of Streptomyces sp.IT-143. It has activity against individual gram-positive bacteria (Micrococcus gaminerae) and individual fungi (Aspergillus fumigatus). And it is also cytotoxic to KB cells. Synonyms: IT-143B. Grades: ≥95%. CAS No. 183485-34-9. Molecular formula: C28H41NO4. Mole weight: 455.63. | |
| Ivdde-OH | Synonyms: 2-(3-Methylbutyryl)-5,5-dimethyl-1,3-cyclohexandione. CAS No. 172611-72-2. Molecular formula: C13H20O3. Mole weight: 224.3. | |
| Ivermectin B1b | Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Dihydroavermectin B1b; 22,23-Dihydroavermectin B1b; Avermectin H2B1b. Grades: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C47H72O14. Mole weight: 861.06. | |
| Izumenolide | It is produced by the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC50 concentration of TEM-2 β-lactamase was 0.01 μg/mL. Synonyms: EM-4615-A; Oxacyclotriacont-3-en-2-one, 16,18-bis(sulfooxy)-30-(2-(sulfooxy)-9-undecenyl)-. CAS No. 76265-39-9. Molecular formula: C40H74O14S3. Mole weight: 875.20. | |
| Jadomycin B | Jadomycin B is an angucyclic natural product produced by Streptomyces venezuelae ISP5230. It exhibits antimicrobial, antitumor activity and inhibits aurora-B kinase and DNA cleaving. It was also shown to be effective against a variety of staphylococci. Synonyms: 1-(sec-butyl)-12-((4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-hydroxy-5-methyl-8H-benzo[b]oxazolo[3,2-f]phenanthridine-2,8,13(1H,3aH)-trione; 8H-Benzo(b)oxazolo(3,2-f)phenanthridine-2,8,13(1H,3aH)-trione, 12-((2,6-dideoxyhexopyranosyl)oxy)-7-hydroxy-5-methyl-1-(1-methylpropyl)-. Grades: ≥98% by HPLC. CAS No. 149633-99-8. Molecular formula: C30H31NO9. Mole weight: 549.6. | |
| Janthinocin A | It is produced by the strain of Janthinobacterium lividum. Janthinocin A has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. CAS No. 131086-52-7. Molecular formula: C57H84N12O16. Mole weight: 1193.34. | |
| Janthinocin B | It is produced by the strain of Janthinobacterium lividum. Janthinocin B has strong activity of anti-gram-positive bacteria and moderate anti-gram-negative bacteria, and has strong inhibitory effect on drug-resistant staphylococcus such as penicillin, tetracycline, erythromycin, methicillin and gentamicin. Synonyms: 8-(alpha,beta-Didehydro-beta-hydroxytryptophan)janthinocin A; Janthinocin A, 8-(alpha,beta-didehydro-beta-hydroxytryptophan)-. CAS No. 131086-53-8. Molecular formula: C57H82N12O16. Mole weight: 1191.33. | |
| Janthitrem B | It is a tremorgenic mycotoxin produced by the strain of Penicillium Janthinellum. Synonyms: 34-deoxy-34,35-didehydro-janthitrem E; (2R, 3R, 4bS, 6aS, 9S, 9aR, 15bS, 15cR, 17aS)-10, 10, 12, 12, 15b, 15c-hexamethyl-2-(prop-1-en-2-yl)-2, 3, 5, 6, 6a, 7, 9, 9a, 10, 12, 15, 15b, 15c, 16, 17, 17a-hexadecahydro-4bH-chromeno[5', 6':6, 7]indeno[1, 2-b]pyrano[4', 3':3, 4]cyclopenta[1, 2-f]indole-3, 4b, 9-triol; 4bH-Pyrano[2'', 3'':5', 6']benz[1', 2':6, 7]indeno[1, 2-b]pyrano[4', 3':3, 4]cyclopent[1, 2-f]indole-3, 4b, 9-triol, 2, 3, 5, 6, 6a, 7, 9, 9a, 10, 12, 15, 15b, 15c, 16, 17, 17a-hexadecahydro-10, 10, 12, 12, 15b, 15c-hexamethyl-2-(1-methylethenyl)-, (2R, 3R, 4bS, 6aS, 9S, 9aR, 15bS, 15cR, 17aS)-. CAS No. 73561-90-7. Molecular formula: C37H47NO5. Mole weight: 585.77. | |
| JBIR-15 | JBIR-15 is an aspochracin derivative metabolized from Aspergillus sclerotiorum. It exhibits antifungal activity against C. albicans. Synonyms: Antibiotic JBIR-15; (2E,4E,6E)-N-[(3S,6S,9S)-3,7-dimethyl-6-(1-methylethyl)-2,5,8-trioxo-1,4,7-triazacyclododec-9-yl]-2,4,6-octatrienamide. Grades: ≥95%. CAS No. 1198588-57-6. Molecular formula: C22H34N4O4. Mole weight: 418.53. | |
| Jenamidine A | It inhibited K-562 proliferation of chronic myeloid leukemia cells with Gl50 of 1.9 μg/mL. Molecular formula: C13H18N2O3. Mole weight: 250.29. | |
| Jietacin A | Jietacin A is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. Synonyms: Jietacine A; BRN 5538455; 1-(Ethenyl-ONN-azoxy)-14-methyl-8-pentadecanone. CAS No. 109766-61-2. Molecular formula: C18H34N2O2. Mole weight: 310.47. | |
| Jietacin B | Jietacin B is originally isolated from Str. sp. KP-197. It is found to be resistant to nematode, it can 100% kill Burs helenchus Lignicolus with the concentration of 0.25μg/mL, which is 10 times stronger than Avermectin B1a. CAS No. 109766-62-3. Molecular formula: C19H36N2O2. Mole weight: 324.50. | |
| JMV 390-1 | JMV 390-1 has been found to be an inhibitor of the major neurotensin and neuromedin N degrading enzymes and could probably show analgesic activities. Synonyms: Jmv-390-1; Jmv390-1; N-[(2R)-4-Hydroxyamino)-1,4-dioxo-2-(phenylmethyl)butyl]-L-isoleucyl-L-leucine. Grades: ≥95% by HPLC. CAS No. 148473-36-3. Molecular formula: C23H35N3O6. Mole weight: 449.54. | |
| Josamycin | Josamycin is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Synonyms: YL-704A3; YL 704A3; YL 704 A3; Leucomycin A3; Turimycin A5; Kitasamycin A3; Josamycine. Grades: 95%. CAS No. 16846-24-5. Molecular formula: C42H69NO15. Mole weight: 828. | |
| Juglomycin A | Juglomycin A is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (-)-Juglomycin A; 1,4-Naphthalenedione,5-hydroxy-2-[(2R,3R)-tetrahydro-3-hydroxy-5-oxo-2-furanyl]-. CAS No. 38637-88-6. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Juglomycin B | Juglomycin B is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (+/-)-juglomycin A. CAS No. 38637-89-7. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Juvenimicin A2 | It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A2 can resist gram-positive bacteria and individual gram-negative bacteria. Synonyms: BRN 1413776; 6-De(2-oxoethyl)-4'-deoxy-6-methylcirramycin A1. CAS No. 61417-47-8. Molecular formula: C30H51NO8. Mole weight: 553.73. | |
| K-1115A | It is produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115A inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide (IC50 = 100 microM), and the production of collagenase in IL-1 alpha-stimulated rat synovial cells (IC50 = 60 microM). Synonyms: K1115 A; 2-Anthracenecarboxylic acid, 9,10-dihydro-3,8-dihydroxy-9,10-dioxo-1-propyl-. CAS No. 208525-17-1. Molecular formula: C18H14O6. Mole weight: 326.30. | |
| K1115 B1 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B1 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Synonyms: XR-573. Molecular formula: C22H24O8. Mole weight: 416.42. | |
| K1115 B2 | It is a co-produced compound of K-1115A produced by the strain of Streptomyces griseorubiginosus Mer-K1115. K1115 B2 inhibited the direct binding of activator protein-1 (AP-1) to AP-1 oligonucleotide, and the production of collagenase in IL-1 alpha-stimulated rat synovial cells. Molecular formula: C23H26O9. Mole weight: 446.45. | |
| K-13 | K-13 is a noncompetitive inhibitor of angiotensin I converting enzyme from Micromonospora halophytica subsp. exilisia K-13. Synonyms: L-Tyrosine, N-acetyl-L-tyrosyl-L-tyrosyl-3-hydroxy-, cyclic (1-3(sup 3))-ether. CAS No. 108890-90-0. Molecular formula: C29H29N3O8. Mole weight: 547.55. | |
| K-252b | A staurosporine analogue isolated from a nocardiopsis strain; a potent inhibitor of protein kinase C. K-252b exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents; also active against other kinases, notably myosin light chain kinase, camp-dependent protein kinase (PKA), protein kinase C (PKC) and cgmp-dependent protein kinase (PKG). Synonyms: (9r,10s,12s)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid. Grades: >98% by HPLC. CAS No. 99570-78-2. Molecular formula: C26H19N3O5. Mole weight: 453.45. | |
| K-252c | K252c, a metabolite product of Nocardiopsis Sp., has been found to be a protein kinase C inhibitor and exhibit antiviral activities against GCV-sensitive and-resistant strains at some extent. Uses: K252c inhibits protein kinase c. its reported ic50 value of 214 nm on rat brain enzyme k252c is cytotoxic for a549 and p388 cancer celllines showing ic50 = 2-3 μm. Synonyms: Staurosporine aglycone; K252C; 6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one. Grades: ≥97%. CAS No. 85753-43-1. Molecular formula: C20H13N3O. Mole weight: 311.34. | |
| K 259-2 | K-259-2, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase, was isolated from the cultured broth of Micromonospora olivasterospora K-259. IC50 values for the effect of K-259-2 against Ca2+ and calmodulin-stimulated activity of the enzyme preparations from bovine brain and heart were 6.6 and 2.9 microM, respectively. Synonyms: K-259-2; 1,6,8-Trihydroxy-3-[(Z)-2-ethyl-2-butenyl]-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid. CAS No. 102819-46-5. Molecular formula: C21H18O7. Mole weight: 382.36. | |
| K 41 | K 41 is originally isolated from Streptomyces hygroscopicus K-41 with anti-gram-positive bacteria activity. Synonyms: (29S)-9,13:17,20:21,24-trianhydro-4,8,10,12,14,18,19,22,23,26,28,30-dodecadeoxy-4,12,14,26,28-pentamethyl-6,16-di-C-methyl-5,6,11,15-tetra-O-methyl-27-O-[(2R,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]-L-xylo-L-manno-α-D-gluco-L-ribo-α-L-gluco-D-glycero-3,13,29-triacontotriulo-13,16-furanose-3,7:29,25-dipyranosonic acid. CAS No. 53026-37-2. Molecular formula: C48H82O18. Mole weight: 947.15. | |
| KA 7038IV | KA 7038IV is originally isolated from Streptomyces sp. KA-7038 with anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity. Synonyms: Antibiotic KA 7038IV; BRN 1387553; 2-Amino-3,6-dihydroxy-4-methoxy-5-(methylamino)cyclohexyl 2,6-diamino-2,3,4,6-tetradeoxyhexopyranoside. CAS No. 73491-60-8. Molecular formula: C14H30N4O5. Mole weight: 334.41. | |
| Kalafungin | Kalafungin is a quinone antibiotic produced by the strain of Str. tanashiensis Kala (NRRL 3215). It has anti-gram-positive bacterial and fungal effects as well as anti-parasite activity. Synonyms: Kalamycin; NSC137443; Antibiotic U-19,718; 3,3a,5,11b-Tetrahydro-7-hydroxy-5-methyl-2H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione. Grades: ≥95%. CAS No. 11048-15-0. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Kalimantacin A | Kalimantacin A is originally isolated from Alcaligenes sp. YL-02632S. It has anti-Gram-positive bacteria (including multi-drug resistant bacteria) and some gram-negative bacteria activities. CAS No. 174513-95-2. Molecular formula: C30H48N2O7. Mole weight: 548.71. | |
| Kanamycin acid disulfate | Kanamycin acid sulfate is an aminoglycoside antibiotic produced by Streptomyces. Synonyms: Kanamycin A disulfate. CAS No. 64013-70-3. Molecular formula: C18H40N4O19S2. Mole weight: 680.65. | |
| Kanamycin B | Kanamycin B is an aminoglycoside antibiotic produced by the strain of Str. kanamyceticus. It is used to treat the infection of gram-positive bacteria, gram-negative bacteria and mycobacterium tuberculosis. Uses: Aminoglycoside antibiotic. Synonyms: Bekanamycin; NK-1006; NK1006; NK 1006; Nebramycin V; Aminodeoxykanamycin; (1R,2S,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside. Grades: ≥95%. CAS No. 4696-76-8. Molecular formula: C18H37N5O10. Mole weight: 483.51. | |
| Kanchanamycin C | Kanchanamycin C is originally isolated from Str. olivaceus TU4018. It has anti-gram positive and negative bacteria, yeast and filamentous fungus action. Molecular formula: C54H91N3O17. Mole weight: 1054.31. | |
| Kanglemycin A | Kanglemycin A (KglA) is related to rifampicin, an antibiotic that functions by binding to bacterial RNA polymerase. KglA binds bacterial RNA polymerase at the rifampicin-binding pocket but maintains potency against RNA polymerases containing rifampicin-resistant mutations. KglA has antibiotic activity against rifampicin-resistant Gram-positive bacteria and multidrug-resistant Mycobacterium tuberculosis. Synonyms: Antibiotic 1747; Rifamycin, 20-(1-(3-carboxy-2,2-dimethyl-1-oxopropoxy)ethyl)-20-demethyl-27-O-demethyl-1,4-dideoxy-27-O-(2,6-dideoxy-3,4-O-methylene-beta-D-ribo-hexopyranosyl)-1,4-dihydro-1,4-dioxo-; Kanglemeisu A; KglA. CAS No. 114153-91-2. Molecular formula: C50H63NO19. Mole weight: 982.03. | |
| Kapurimycin A1 | It is originally isolated from Str. sp. DO-15. Kapurimycin A1 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: [8-(Acetyloxy)-12-hydroxy-2-(2-methyl-3-propyloxiran-2-yl)-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. CAS No. 132412-65-8. Molecular formula: C27H26O9. Mole weight: 494.49. | |
| Kapurimycin A2 | It is originally isolated from Str. sp. DO-15. Kapurimycin A2 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: 8-Acetyloxy-2-(3-ethyl-2-methyloxiran-2-yl)-8,9,10,11-tetrahydro-12-hydroxy-4,11-dioxo-4H-anthra[1,2-b]pyran-5-acetic acid; [8-(Acetyloxy)-2-(3-ethyl-2-methyloxiran-2-yl)-12-hydroxy-4,11-dioxo-8,9,10,11-tetrahydro-4H-anthra[1,2-b]pyran-5-yl]acetic acid. Grades: ≥98%. CAS No. 132412-64-7. Molecular formula: C26H24O9. Mole weight: 480.46. | |
| Kapurimycin A3 | It is originally isolated from Str. sp. DO-15. Kapurimycin A3 can resist gram-positive bacteria and a few gram-negative bacteria. Synonyms: 4H-Anthra(1,2-b)pyran-5-acetic acid, 8-(acetyloxy)-8,9,10,11-tetraahydro-12-hydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,11-dioxo-. Grades: >98%. CAS No. 129966-45-6. Molecular formula: C27H24O9. Mole weight: 492.47. | |
| Karalicin | Karalicin is produced by the strain of Pseudomonus fluorescens/putida SS-3. It inhibits herpes simplex virus HSV-1, HSV-2, vaccinia virus, polio virus type I with the IC50 (μg/mL) of 0.004, 0.008, 0.016 and 0.016. Synonyms: 3-O-Acetyl-1-deoxy-1-(4-methoxyphenyl)pentitol. Molecular formula: C14H20O6. Mole weight: 284.30. | |
| Kasugamycin hydrochloride | Kasugamycin hydrochloride is an aminoglycoside antibiotic produced by Streptomyces. It is a broad spectrum antifungal used against yeast and pathogenic fungi such as M. Grisea. Synonyms: D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, hydrochloride (1:1); D-chiro-Inositol, 3-O-[2-amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-α-D-arabino-hexopyranosyl]-, monohydrochloride; Kasugamycin, monohydrochloride; Kasumin. Grades: ≥73.5%. CAS No. 19408-46-9. Molecular formula: C14H26ClN3O9. Mole weight: 415.82. | |
| Katanosin A | Katanosin A is a peptide antibiotic originally isolated from Cytophaga sp. PBJ-5356. It has anti-gram-positive bacterial effect. Synonyms: L-Serine, N-[threo-3-hydroxy-N2-[N-[N-[N-[N2-[N-[threo-3-hydroxy-N-[threo-b-hydroxy-N-(N-D-leucyl-L-leucyl)-L-phenylalanyl]-L-leucyl]-L-leucyl]-D-arginyl]-L-valyl]-L-allothreonyl]glycyl]-L-asparaginyl]-,b1-lactone. CAS No. 116103-86-7. Molecular formula: C57H95N15O17. Mole weight: 1262.45. | |
| Kazusamycin A | A minor member of the leptomycin complex isolated from some streptomyces species; an hydroxylated analogue of leptomycin B, a nuclear export inhibitor; exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity. Synonyms: 3-HYDROXYLEPTOMYCIN B; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-; CL 1957B, PD 114721. Grades: >95% by HPLC. CAS No. 92090-94-3. Molecular formula: C33H48O7. Mole weight: 556.73. | |
| Kazusamycin B | A minor component of the leptomycin complex produced by some streptomyces sp.; an hydroxylated analogue of leptomycin A, a nuclear export inhibitor; displays potent antitumour activity against L1210 and human colon adenocarcinoma, and in vivo activity against P388 lymphocytic leukemia in mice; also possesses strong antibacterial and antifungal activity. Synonyms: PD 124895; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15,17-hexamethyl-8-oxo-. Grades: >95% by HPLC. CAS No. 107140-30-7. Molecular formula: C32H46O7. Mole weight: 542.70. | |
| Kendomycin | Kendomycin is an endothelin receptor antagonist and proteasome inhibitor. It induces apoptosis in lymphoma. It is a potent antibacterial agent against gram-positive and gram-negative bacteria, including MRSA strains. Synonyms: TAN 2162. Grades: >95% by HPLC. CAS No. 183202-73-5. Molecular formula: C29H42O6. Mole weight: 486.64. | |
| Kerriamycin A | Produced by the strain of Str. Violaceolatus, Kerriamycin A has anti-gram-positive bacterial effect and can also prolong the survival time of patients with Ai's ascites cancer. Synonyms: Benz(a)anthracene-1,7,12(2H)-trione, 9-(2,6-dideoxy-3-O-((2S-(2alpha,5beta,6beta))-5-((2,6-dideoxy-beta-L-erythro-hexopyranos-3-ulos-1-yl)oxy)tetrahydro-6-methyl-2H-pyran-2-yl)-beta-D-arabino-hexopyranosyl)-3,4,4a,12b-tetrahydro-3,4a,8-trihydrox. CAS No. 98474-20-5. Molecular formula: C43H54O17. Mole weight: 842.88. | |
| Kerriamycin C | It is produced by the strain of Str. Violaceolatus. Kerriamycin C has anti-gram-positive bacterial effect and can also prolong the survival time of patients with Ai's ascites cancer. Synonyms: Antibiotic A 32Y3; Benz[a]anthracene-1,7,12(2H)-trione,9-[2,6-dideoxy-3-O-[[2S-(2a,5b,6b)]-5-[(2,6-dideoxy-b-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-,[3R-(3a,4aa,12ba)]-. CAS No. 98495-38-6. Molecular formula: C37H46O15. Mole weight: 730.75. | |
Our database is helping our users find suppliers everyday.
