BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
×
Product
Description
Suppliers Website
(-)-cis-3-Aminocyclopentanecarboxylic acid
(-)-(1R,3S)-3-Aminocyclopentanecarboxylic acid is used in the synthesis of aminocyclopentanecarboxylic acid-containing cyclic RGD peptides. It is also used to prepare BMS-457, a potent and selective CCR1 antagonist. Synonyms: (-)-(1R,3S)-3-Aminocyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 3-amino-, (1R,3S)-; (1R,3S)-3-Aminocyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 3-amino-, (1R-cis)-; (1R,3S)-3-Aminocyclopentanecarboxylic acid. Grades: ≥95%. CAS No. 71830-08-5. Molecular formula: C6H11NO2. Mole weight: 129.16.
cis-4-Hydroxy-lomustine
cis-4-Hydroxy-lomustine is an impurity of lomustine which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine. Synonyms: 1-(2-Chloroethyl)-3-(cis-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-(cis-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239724; cis-4-Hydroxy CCNU. Grades: > 95%. CAS No. 52049-26-0. Molecular formula: C9H16ClN3O3. Mole weight: 249.69.
cis-4-Hydroxymellein
It is produced by the strain of Aspergillus ochraceus and Lasiodiplodia theobromae. Synonyms: (3S-cis)-4-hydroxymellein; (3S,4S)-4,8-dihydroxy-3-methylisochroman-1-one; cis-3S,4S-4-Hydroxymellein; 4-Hydroxymellein, (3S-cis-(+))-; 3,4-Dihydro-4beta,8-dihydroxy-3beta-methyl-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3S,4S)-; 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3S-cis)-. CAS No. 60132-20-9. Molecular formula: C10H10O4. Mole weight: 194.18.
cis-Ibuprofen Impurity G
cis-Ibuprofen Impurity G is an impurity of cis-Ibuprofen, an analgesic, anti-inflammatory and antipyretic nonsteroidal drug (NSAID). Grades: > 95%. Molecular formula: C26H32O4. Mole weight: 408.54.
cis-Lacidipine
Z-Isomer of Lacidipine; a dihydropyridine calcium channel blocker. Antihypertensive. Synonyms: (Z)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester. Grades: > 95%. CAS No. 103890-79-5. Molecular formula: C26H33NO6. Mole weight: 455.55.
cis-Montelukast
Cas No. 774538-96-4.
Citreomontanin
A metabolite of penicillium pedemontanum. Synonyms: all-E-citreomontanin; Citreomontanine; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-(7,9,11-trimethyl-1,3,5,7,9,11-tridecahexaenyl)-, (all-E)-; 4-methoxy-5-methyl-6-((1E,3E,5E,7E,9E,11E)-7,9,11-trimethyltrideca-1,3,5,7,9,11-hexaen-1-yl)-2H-pyran-2-one. Grades: 95%. CAS No. 74474-66-1. Molecular formula: C23H28O3. Mole weight: 352.47.
Cladospirone bisepoxide
It is produced by the strain of Cladosporium sp. F-24707. Cladospirone bisepoxide has the ability to inhibit yeast, filamentous fungi, and bacterial, and can inhibit germination of Lepidium sativum at low concentrations. Synonyms: Cladospirone bisepoxide. CAS No. 155866-40-3. Molecular formula: C20H14O7. Mole weight: 366.32.
Clavulanate Potassium (1:1 mixture with silicon dioxide)
Clavulanate Potassium is a semi-synthetic beta-lactamase inhibitor isolated from streptomyces. It contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site. It is used in conjunction with beta-lactamase susceptible penicillins to treat infections caused by beta-lactamase producing organisms. It is commonly combined with amoxicillin or ticarcillin to increase its effectiveness. Uses: Beta-lactamase inhibitors. Synonyms: Amonate; MM-14151; MM14151. Grades: 91.2 % - 107.1 %. CAS No. 61177-45-5. Molecular formula: C8H8KNO5. Mole weight: 237.25.
Clavulanic acid
It is produced by the strain of Streptomyces clavuligerus. Clavulanic acid has a strong inhibition of β-lactamase activity, almost no antibacterial effect. Synonyms: Acido clavulanico; Acide clavulanique; acidum clavulanicum; Clavulansaeure. Grades: 95%. CAS No. 58001-44-8. Molecular formula: C8H9NO5. Mole weight: 199.16.
Clazamycin B
It is produced by the strain of Streptomyces No. NF990-BF4. Clazamycin A has weak activity against gram-positive bacteria, gram-negative bacteria and L1210 cell. Synonyms: Antibiotic 354; (2S-cis)-2-Chloro-5-imino-2,3-dihydro-1H-pyrrolizin-7a(5H)-ol. CAS No. 71774-49-7. Molecular formula: C7H9ClN2O. Mole weight: 172.61.
Clindamycin
Clindamycin is produced by the strain of semi-synthetic lincomycin. The antibacterial spectrum of chloralincomycin is the same as that of Lincomycin, but its antibacterial activity is stronger, and its effect on anaerobic bacteria such as fragile Bacteroides is equivalent to 3-4 times of that of Lincomycin. It can be injected or administered orally, and oral absorption is obviously superior to lincomycin. Synonyms: Dalacine; Chlolincocin; Dalacin C; 7-Chlorolincomycin. Grades: >98%. CAS No. 18323-44-9. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98.
Clindamycin 2-Phosphate
Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat protozoal diseases, such as malaria. It is a common drug used to treat topical acne and can be effective against some methicillin-resistant Staphylococcus aureus (MRSA) infections. An impurity of Clindamycin. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidine-carboxamido)-1-thio-L-threo-α-D-galactooctopyranoside 2-(Dihydrogen Phosphate); 7(S)-Chloro-7-deoxylincomycin 2-Phosphate; Cleocin T; Cleocin Phosphate; Clinadac; Clindagel; Clindesse; Clindets; Dalacin P; Dalacin T; NSC 618653. Grades: >98%. CAS No. 24729-96-2. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96.
Clindamycin Cyclomonophosphate
Clindamycin Cyclomonophosphate is an impurity of Clindamycin, which is a semi-synthetic antibiotic prepared from Lincomycin. Synonyms: [(1R,2R)-1-Methyl-4-propyl-2-pyrrolidinyl]{(2S)-1-[(4R,7S)-2-hydroxy-7-hydroxy-4-(methylthio)-2-oxo-1,3,5-trioxa-2-phosphahexahydroinden-6-yl]-2-chloropropylamino}formaldehyde. Molecular formula: C18H32ClN2O7PS. Mole weight: 486.95.
CLIP 86-100 acetate
CLIP (86-100) is the 86-100 amino acid fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain in the HLA-II antigen binding slots, which is considered to play a key role in the assembly and transport of MHC class II alphabetaII complexes by interacting with the binding sites of class II peptides. Synonyms: L-Prolyl-L-valyl-L-seryl-L-lysyl-L-methionyl-L-arginyl-L-methionyl-L-alanyl-L-threonyl-L-prolyl-L-leucyl-L-leucyl-L-methionyl-L-glutaminyl-L-alanine acetate; H-Pro-Val-Ser-Lys-Met-Arg-Met-Ala-Thr-Pro-Leu-Leu-Met-Gln-Ala-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C74H132N20O21S3. Mole weight: 1734.17.
Clomocycline
It is produced by the strain of Streptomyces aureofaciens. Clomocycline has anti-gram-positive and negative bacteria activity. Synonyms: Chlormethylenecycline; N'-Methylolo-chlortetracycline; 7-Chloro-N-(hydroxymethyl)tetracycline; Megaclor. Grades: 95%. CAS No. 1181-54-0. Molecular formula: C23H25ClN2O9. Mole weight: 508.91.
Clonostachin
Clonostachin is a peptide amino alcohol produced by Clonostachys sp. F5898. It has the effect of inhibiting platelet aggregation. Molecular formula: C78H134N14O25. Mole weight: 1667.97.
Cloxacillin
It is produced by the strain of semisynthetic isoxazole penicillin. Cloxacillin is a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. It is a chlorinated derivative of oxacillin and is an antibiotic useful for the treatment of a number of bacterial infections. It binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thus preventing the cross-linkage of peptidoglycans, which leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. It is used against staphylococci that produce beta-lactamase, due to its large R chain, which does not allow the beta-lactamases to bind. It was discovered and developed by Beecham. Uses: Cloxacillin is an antibiotic useful for the treatment of a number of bacterial infections. Synonyms: Cloxacillinum; Cloxacilina; Syntarpen; Tegopen; (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin. Grades: 98%. CAS No. 61-72-3. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
CMD178 TFA
CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grades: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05.
Cochinmicin I is produced by the strain of Microbispora sp. Cochinmicin I has the antagonistic effect of endothelin and it is the most active of all components. CAS No. 143728-97-6. Molecular formula: C46H47N7O12. Mole weight: 889.90.
Cochinmicin II
Cochinmicin II is produced by the strain of Microbispora sp. Cochinmicin II has the antagonistic effect of endothelin. CAS No. 143728-98-7. Molecular formula: C46H46ClN7O12. Mole weight: 924.35.
Cochinmicin III
Cochinmicin III is produced by the strain of Microbispora sp. Cochinmicin III has the antagonistic effect of endothelin. CAS No. 143728-99-8. Molecular formula: C46H46ClN7O12. Mole weight: 924.35.
Cochinmicin IV
Cochinmicin IV is produced by the strain of Microbispora sp. Cochinmicin IV has the antagonistic effect of endothelin. Molecular formula: C46H46ClN7O13. Mole weight: 940.35.
Cochinmicin V
Cochinmicin V is produced by the strain of Microbispora sp. Cochinmicin V has the antagonistic effect of endothelin. CAS No. 146925-27-1. Molecular formula: C46H47N7O12. Mole weight: 889.90.
Coenzyme A
Coenzyme A is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. Coenzyme A plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. About 4% of cellular enzymes utilize CoA as a substrate. Synonyms: CoASH; Coenzyme A (free acid); Depot-Zeel; Coenzyme ASH; 3'-phosphoadenosine 5'-{3-[ (3R) -3-hydroxy-2, 2-dimethyl-4-oxo-4- ({3-oxo-3-[ (2-sulfanylethyl) amino]propyl}amino) butyl] dihydrogen diphosphate}. Grades: >85%. CAS No. 85-61-0. Molecular formula: C21H36N7O16P3S. Mole weight: 767.53.
COG 133 acetate
COG 133 acetate is a fragment of ApoE that exhibits anti-inflammatory and neuroprotective effects and could also be an antagonist at α7 nicotinic acetylcholine receptors. Synonyms: Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-NH2.CH3CO2H; N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-L-leucinamide acetic acid; L-Leucinamide, N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-, acetate (1:1). Grades: ≥95%. CAS No. 2763583-75-9. Molecular formula: C99H185N37O21. Mole weight: 2229.76.
COG 133 TFA
COG133 is a peptide fragment of ApoE that corresponds to residues 133-149 of the ApoE LDL receptor-binding domain and an antagonist of α7 nicotinic acetylcholine receptors (nAChRs; IC50 = 720 nM). It suppresses TNF-α and nitric oxide (NO) release in BV-2 microglia when used at concentrations ranging from 10 to 50 μM. Synonyms: L-Leucinamide, N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-, 2,2,2-trifluoroacetate (1:1); Ac-Leu-Arg-Val-Arg-Leu-Ala-Ser-His-Leu-Arg-Lys-Leu-Arg-Lys-Arg-Leu-Leu-NH2.TFA; N-acetyl-L-leucyl-L-arginyl-L-valyl-L-arginyl-L-leucyl-L-alanyl-L-seryl-L-histidyl-L-leucyl-L-arginyl-L-lysyl-L-leucyl-L-arginyl-L-lysyl-L-arginyl-L-leucyl-L-leucinamide trifluoroacetic acid. Grades: 98%. CAS No. 2828432-37-5. Molecular formula: C99H182F3N37O21. Mole weight: 2283.78.
Collagenase Chromophore Substrate Test Substance is an enzyme substrate. Synonyms: 4-phenylazobenzyl-oxycarbonyl-l-prolyl-l-leucine; 1-[ ({4-[ (E) -Phenyldiazenyl]phenyl}methoxy) carbonyl]-L-prolyl-L-leucine. CAS No. 98640-71-2. Molecular formula: C25H30N4O5. Mole weight: 466.53.
Collagen Type I α1 chain (502-516)
Collagen Type I α1 chain (502-516) corresponds to the integrin alpha2beta1 binding site of collagen I. The GER motif is crucial for recognition. Synonyms: Collagen α1(l) (502-516); H-Gly-Phe-Hyp-Gly-Glu-Arg-Gly-Val-Glu-Gly-Pro-Hyp-Gly-Pro-Ala-NH2. Grades: ≥95%. Molecular formula: C63H95N19O21. Mole weight: 1454.54.
Collagen Type II Fragment
Collagen Type II Fragment, the collagen II fragment, is a peptide analog of the antigenic determinant of type II collagen, which can prevent the onset of collagen-induced arthritis in vivo. Synonyms: (Ala260,Hyp261,Asn263)-Collagen Type II (245-270); H-Pro-Thr-Gly-Pro-Leu-Gly-Pro-Lys-Gly-Gln-Thr-Gly-Glu-Leu-Gly-Ala-Hyp-Gly-Asn-Lys-Gly-Glu-Gln-Gly-Pro-Lys-OH; L-prolyl-L-threonyl-glycyl-L-prolyl-L-leucyl-glycyl-L-prolyl-L-lysyl-glycyl-L-glutaminyl-L-threonyl-glycyl-L-alpha-glutamyl-L-leucyl-glycyl-L-alanyl-(4R)-4-hydroxy-L-prolyl-glycyl-L-asparagyl-L-lysyl-glycyl-L-alpha-glutamyl-L-glutaminyl-glycyl-L-prolyl-L-lysine; L-Lysine, L-prolyl-L-threonylglycyl-L-prolyl-L-leucylglycyl-L-prolyl-L-lysylglycyl-L-glutaminyl-L-threonylglycyl-L-α-glutamyl-L-leucylglycyl-L-alanyl-(4R)-4-hydroxy-L-prolylglycyl-L-asparaginyl-L-lysylglycyl-L-α-glutamyl-L-glutaminylglycyl-L-prolyl-. Grades: ≥95%. CAS No. 144703-90-2. Molecular formula: C106H174N32O37. Mole weight: 2488.74.
Collinin
Collinin is a coumarin isolated from Flindersia maculosa and other species. Collinin induces apoptosis of human Jurkat T cells and is active against drug-resistant strains of Mycobacterium tuberculosis. Grades: >95% by HPLC. CAS No. 34465-83-3. Molecular formula: C20H24O4. Mole weight: 328.41.
Confluentic acid
It is produced by the strain of lichens Lecidea confluens, Pertusaria tuberculifera and P. globularis. It is also isolated from L. tumida, L. macrocarpa and Herpothallon sanguineum. Synonyms: NSC 249982; Benzoic acid, 2-hydroxy-4-methoxy-6-(2-oxoheptyl)-, 4-carboxy-3-methoxy-5-pentylphenyl ester; 2-Hydroxy-4-methoxy-6-(2-oxoheptyl)benzoic acid 4-carboxy-3-methoxy-5-pentylphenyl ester; 2-Methoxy-4-[2-(2-oxoheptyl)-4-methoxy-6-hydroxybenzoyloxy]-6-pentylbenzoic acid; Confluentinsaeure; Confluentin. Grades: ≥95%. CAS No. 6009-12-7. Molecular formula: C28H36O8. Mole weight: 500.58.
Congrayanic acid
It has been shown to be a constituent of the Australian lichen Gymnoderma melacarpum (Wils.) Yoshim. Synonyms: Benzoic acid, 3-(2-carboxy-5-methoxy-3-methylphenoxy)-2-heptyl-4,6-dihydroxy-; 2-(3'-carboxy-2'-heptyl-4',6'-dihydroxyphenoxy)-4-methoxy-6-methylbenzoic acid. CAS No. 74683-08-2. Molecular formula: C23H28O8. Mole weight: 432.46.
Conophylline
Cas No. 142741-24-0.
Conopressin G
Conopressin G is a vasotocin-like peptide isolated from the venom of the worm-hunting snail (conus imperialis). Synonyms: Glycinamide, L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1?6)-disulfide; Conopressin G (Conus geographus); Conopressin L1; Lysine-conopressin (Erpobdella octoculata); Lysine-conopressin (Lymnaea stagnalis); H-Cys-Phe-Ile-Arg-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-phenylalanyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Lys-Conopressin-G. Grades: 95%. CAS No. 111317-91-0. Molecular formula: C44H71N15O10S2. Mole weight: 1034.26.
Conopressin S acetate
Conopressin S acetate, isolated from Conus striatus, has a high affinity with vasopressin V1b receptor (AVPR1B) with a Ki of 8.3 nM. Synonyms: Con-S acetate; Conopressin A1 acetate; H-Cys-Ile-Ile-Arg-Asn-Cys-Pro-Arg-Gly-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-isoleucyl-L-isoleucyl-L-arginyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide acetate. Grades: ≥95%. Molecular formula: C43H77N17O12S2. Mole weight: 1088.32.
Conorlobaridone
It is the depsidone isolated from the lichen Xanthoparmelia xanthosorediata. Synonyms: 3,8-Dihydroxy-1-pentanoyl-6-propyl-dibenzo[b,e][1,4]dioxepin-11-one; Conlorlobaridon; 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 3,8-dihydroxy-1-(1-oxopentyl)-6-propyl-. CAS No. 71521-80-7. Molecular formula: C21H22O6. Mole weight: 370.40.
Conphysodalic acid
Conphysodalic acid is a secondary metabolite of the lichen Hypogymnia physodes. CAS No. 111720-42-4. Molecular formula: C20H18O10. Mole weight: 418.35.
Conprotocetraric acid
Conprotocetraric acid, the β-orcinol depsidone, has been identified in the lichen, Usnea trichodeoides. Synonyms: 6,14-dihydroxy-7,15-bis(hydroxymethyl)-4,12-dimethyl-10-oxo-2,9-dioxatricyclo[9.4.0.0(3,8)]pentadeca-1(11),3(8),4,6,12,14-hexaene-5-carboxylic acid; 3,8-dihydroxy-4,9-bis(hydroxymethyl)-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. Molecular formula: C18H16O9. Mole weight: 376.31.
Constipatic acid, a fatty acid found in several lichen species, has been isolated from Xanthoparmelia constipata, Parmelia xanthosorediata, Heterodermia appendiculata, Lepraria coriensis, Punctelia negata and Rhizoplaca melanophthalma and so on. Synonyms: 2-(14'-hydroxypentadecyl)-4-methyl-5-oxo-2,5-dihydrofuran-3-carboxylic acid. CAS No. 73036-28-9. Molecular formula: C21H36O5. Mole weight: 368.51.
Consuccinprotocetraric acid
Consuccinprotocetraric acid, the β-orcinol depsidone, has been identified in the lichen, Flavoparmelia succinprotocetrarica. Synonyms: 9-(((3-carboxypropanoyl)oxy)methyl)-3,8-dihydroxy-4-(hydroxymethyl)-1,6-dimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. Molecular formula: C22H20O12. Mole weight: 476.39.
Contortin
It was the first intestinal antigen of the sheep parasite Haemonchus contortus and was used to induce significant levels of protection when inoculated in lambs. Synonyms: 1,1'-(2,2'-dihydroxy-4,4',6,6'-tetramethoxy-5,5'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(ethan-1-one); Ethanone, 1,1'-(2,2'-dihydroxy-4,4',6,6'-tetramethoxy-5,5'-dimethyl(1,1'-biphenyl)-3,3'-diyl)bis-. CAS No. 91925-83-6. Molecular formula: C22H26O8. Mole weight: 418.44.
Convirensic acid
Convirensic acid, a β-orcinol depsidone, has been identified in the lichens, Sulcaria virens. Synonyms: 3,9-dihydroxy-10-(hydroxymethyl)-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid. CAS No. 79586-42-8. Molecular formula: C18H16O8. Mole weight: 360.32.
Copal resin
Copal resin is an aromatic resin from the Copal tree Protium Copal (Burseraceae) used for the ceremonial burning of incense and other purposes.
Copeptin (human)
Copeptin (CT-ProAVP) initially produces the same amount of (Arg8)-Vasopressin (AVP), which has become a prognostic indicator for a variety of diseases, such as sepsis, community-acquired pneumonia, chronic obstructive pulmonary failure, heart failure, and myocardial infarction. Synonyms: H-Ala-Ser-Asp-Arg-Ser-Asn-Ala-Thr-Gln-Leu-Asp-Gly-Pro-Ala-Gly-Ala-Leu-Leu-Leu-Arg-Leu-Val-Gln-Leu-Ala-Gly-Ala-Pro-Glu-Pro-Phe-Glu-Pro-Ala-Gln-Pro-Asp-Ala-Tyr-OH; L-Alanyl-L-seryl-L-α-aspartyl-L-arginyl-L-seryl-L-asparaginyl-L-alanyl-L-threonyl-L-glutaminyl-L-leucyl-L-α-aspartylglycyl-L-prolyl-L-alanylglycyl-L-alanyl-L-leucyl-L-leucyl-L-leucyl-L-arginyl-L-leucyl-L-valyl-L-glutaminyl-L-leucyl-L-alanylglycyl-L-alanyl-L-prolyl-L-α-glutamyl-L-prolyl-L-phenylalanyl-L-α-glutamyl-L-prolyl-L-alanyl-L-glutaminyl-L-prolyl-L-α-aspartyl-L-alanyl-L-tyrosine; CT-ProAVP. Grades: ≥95%. CAS No. 78362-34-2. Molecular formula: C177H279N49O58. Mole weight: 4021.46.
It is produced by the strain of Paecilomyces variotii SANK 21086. It has the activity of removing annual weeds (0.5 kg/he) and has no antibacterial effect. Synonyms: 14-Dihydroxycornestin; (4R,5S,8S,9Z)-9-ethylidene-5,8-dihydroxy-4-propyl-4,5,7,8,9,10-hexahydro-1H-cyclonona[c]furan-1,3,6-trione. CAS No. 123068-35-9. Molecular formula: C16H20O6. Mole weight: 308.33.
Coronatoquinone
Coronatoquinone is a pyranonaphthazarin from the Lichen Pseudocyphellaria coronata. CAS No. 299190-12-8. Molecular formula: C15H12O8. Mole weight: 320.25.
Coronopilin
Coronopilin is a sesquiterpene lactone. Synonyms: 10αH-Ambros-11(13)-en-12-oic acid, 1,6β-dihydroxy-4-oxo-, γ-lactone (8CI). CAS No. 2571-81-5. Molecular formula: C15H20O4. Mole weight: 264.32.
Cortistatin-17 (human)
Cortistatin-17, a structural analogue of somatostatin, binds to all somatostatin receptor subtypes (SSTR) in a manner similar to rat cortistatin. Its inhibition on the cAMP production of forskolin-stimulated in chinese hamster ovary cells expressing SSTR2-5 are dose-dependent, but slightly less efficient than somatostatin-14. Like rat cortistatin, it affects sleep and wake patterns in rats. It reduces light slow wave sleep (SWS1) and increases deep slow wave sleep (SWS2) in a dose-dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms. Synonyms: H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys5-Cys16); L-alpha-aspartyl-L-arginyl-L-methionyl-L-prolyl-D-cysteinyl-D-arginyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (5->16)-disulfide; L-α-Aspartyl-L-arginyl-L-methionyl-N-[(4R, 7S, 10R, 13R, 16S, 19S, 22R, 25S, 28S, 31S, 34R, 37S)-19-(4-aminobutyl)-4-{[(1S)-5-amino-1-carboxypentyl]carbamoyl}-31-(2-amino-2-oxoethyl)-13, 25, 28-tribenzyl-34-(3-carbamimidamidopropyl)-16-[(1R)-1-hydroxyethyl]-7, 10-bis(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36-undecaoxo-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35-undecaazacyclooctatriacontan-37-yl]-L-prolinamide. Grades: 95%. CAS No. 189450-19-9. Molecular formula: C96H139N27O24S3. Mole weight: 2151.53.
Cortistatin-29 (human)
Cortistatin-29 (human), an anti-inflammatory and immunomodulatory factor, has potential multistep therapeutic effects in the treatment of septic shock and Crohn's disease. Synonyms: Pyr-Glu-Gly-Ala-Pro-Pro-Gln-Gln-Ser-Ala-Arg-Arg-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys17-Cys28); L-Lysine, 5-oxo-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-prolyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-seryl-L-alanyl-L-arginyl-L-arginyl-L-α-aspartyl-L-arginyl-L-methionyl-L-prolyl-L-cysteinyl-L-arginyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-, cyclic (17?28)-disulfide; CST (human). Grades: ≥95%. CAS No. 1815618-16-6. Molecular formula: C149H223N47O42S3. Mole weight: 3440.86.
Cortistatin-29 (rat)
Cortistatin-29 is a neuropeptide that has structurally similarity to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Synonyms: Pyr-Glu-Arg-Pro-Pro-Leu-Gln-Gln-Pro-Pro-His-Arg-Asp-Lys-Lys-Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bridge: Cys17-Cys28); 5-oxo-L-prolyl-L-α-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-α-aspartyl-L-lysyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-L-lysine, cyclic (17?28)-disulfide; L-pyroglutamyl-L-alpha-glutamyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-prolyl-L-prolyl-L-histidyl-L-arginyl-L-alpha-aspartyl-L-lysyl-L-lysyl-L-prolyl-D-cysteinyl-D-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-phenylalanyl-D-seryl-L-seryl-L-cysteinyl-L-lysine (17->28)-disulfide. Grades: ≥95%. CAS No. 1815618-17-7. Molecular formula: C161H240N46O41S2. Mole weight: 3540.05.
Cotylenin F
It is produced by the strain of Cladosporium sp. It has the function of plant growth regulation. CAS No. 58045-03-7. Molecular formula: C33H54O11. Mole weight: 626.77.
CovidyteTM ED450
CovidyteTM ED450, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Dabcyl (quencher) at the N-terminus and Edans (donor) at the C-terminus, respectively, and the fluorescence of Edans is effectively quenched by Dabcyl when the peptide is intact. When it is hydrolyzed by the coronavirus protease, the fluorescence of the Edans fragment is significantly enhanced because its fluorescence is no longer quenched by Dabcyl. Edans fluorescence intensity can effectively monitor the activity of coronavirus protease. It is a handy tool for screening coronavirus protease inhibitors. (excitation at 336, emission at 455 nm). Synonyms: EDANS-Val-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys(DABCYL)-Met-OH. Molecular formula: C82H125N23O22S2. Mole weight: 1849.14.
CovidyteTM EN450
CovidyteTM EN450, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Dabcyl (quencher) at the N-terminus and Edans (donor) at the C-terminus, respectively, and the fluorescence of Edans is effectively quenched by Dabcyl when the peptide is intact. When it is hydrolyzed by the coronavirus protease, the fluorescence of the Edans fragment is significantly enhanced because its fluorescence is no longer quenched by Dabcyl. Edans fluorescence intensity can effectively monitor the activity of coronavirus protease. It is a handy tool for screening coronavirus protease inhibitors. (excitation at 350, emission at 460 nm). Synonyms: H-Lys(DABCYL)-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-EDANS. Molecular formula: C95H141N25O24S2. Mole weight: 2081.42.
CovidyteTM IF670
CovidyteTM IF670, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide QuencherTM 5 (TQ5) as a quencher at the N-terminal and iFluorTM 670 as a fluorescent donor at the C-terminal, respectively. When the peptide is intact, the fluorescence of iFluorTM 670 is effectively quenched by TQ5. When the peptide is hydrolyzed by the coronavirus proteases, the fluorescence of the iFluorTM 670 fragment is no longer quenched by TQ5, and the fluorescence is significantly enhanced. The fluorescence intensity of iFluorTM 670 can be used to effectively monitor the activity of coronavirus proteases. It is a powerful high-throughput screening tool for searching inhibitors of coronavirus protease. Compared to commonly used EDANS substrates, such as CovidyteTM ED450, the iFluorTM 670 substrate has stronger and longer fluorescence and is less disturbed by colored compounds that often cause false positive hits. (excitation at 656, emission at 670 nm). Synonyms: H-Cys(iFluor 647)-Val-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys(TQ5)-Met-OH. Molecular formula: C58H105N19O19S2 + dye. Mole weight: 3068.
CovidyteTM TF670
CovidyteTM TF670, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide QuencherTM 5 (TQ5) as a quencher at the N-terminal and Tide FluorTM 5 (TF5) as a fluorescence donor at the C-terminal, respectively. When the peptide is intact, the fluorescence of TF5 is effectively quenched by TQ5. When the peptide is hydrolyzed by the coronavirus proteases, the fluorescence of the TF5 fragment is no longer quenched by TQ5, and the fluorescence is significantly enhanced. The fluorescence intensity of TF5 can be used to effectively monitor the activity of coronavirus proteases. It is a powerful high-throughput screening tool for searching inhibitors of coronavirus protease. TQ5-TF5 pair has proved to be an extremely effective FRET pair for the development of FRET protease substrates. Compared to commonly used EDANS substrates, such as CovidyteTM EN450, the TF670 substrate has stronger, longer fluorescence and is less disturbed by colored compounds that often cause false positive hits. (excitation at 640, emission at 680 nm). Synonyms: H-Lys(TQ5)-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Cys(TF5)-OH. Molecular formula: C71H121N21O22S2 + dye. Mole weight: 3620.
CP 31398 dihydrochloride hydrate
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride, hydrate (1:2:1); CP31398 dihydrochloride hydrate; CP-31398 dihydrochloride hydrate; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride hydrate. Grades: ≥95%. CAS No. 1853109-76-8. Molecular formula: C22H26N4O.2HCl.H2O. Mole weight: 453.41.
C-Peptide 1 (rat)
C-Peptide 1 (rat) specifically binds to G-protein-coupled membrane receptors in the nanomolar concentration range, and subsequently activates Ca2+-dependent intracellular signaling pathways. This leads to a stimulation of the activity of both Na+-K+-ATPase, and endothelial nitric oxide synthase. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover. Synonyms: Insulin 1 Precursor (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-prolyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-L-alpha-glutamyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine. Grades: ≥95%. CAS No. 41475-27-8. Molecular formula: C140H228N38O51. Mole weight: 3259.53.
C-Peptide 2 (rat)
C-Peptide 2 (rat), a peptide composed of 31 amino acid residues, can effectively improve glucose utilization in streptozotocin induced diabetic rats. It is a component of proinsulin, and can inhibit glucose-induced insulin secretion. Synonyms: Preproinsulin 2 (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Ala-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-alanyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine; Insulin 2 Precursor (57-87) (rat); Proinsulin 2 (33-63) (rat). Grades: ≥95% by HPLC. CAS No. 41594-08-5. Molecular formula: C135H222N38O49. Mole weight: 3161.43.
CRAMP-18 (mouse)
CRAMP-18 (mouse) corresponds to the functional region of the antimicrobial peptide CRAMP and has strong antibacterial activity against a variety of bacteria, with no hemolytic activity (MIC = 12.5-50 μM). Synonyms: H-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-OH; glycyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-lysyl-L-lysyl-L-isoleucyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-glutaminyl-L-lysyl-L-leucine. Grades: 95%. CAS No. 256639-17-5. Molecular formula: C101H171N27O24. Mole weight: 2147.64.
C-Reactive Protein (CRP) 201-206 acetate
C-Reactive Protein (CRP) 201-206 acetate is the 201-206 fragment of C-Reactive Protein, a prototype marker of inflammation and a cardiovascular risk marker that may promote atherosclerosis. Synonyms: H-Lys-Pro-Gln-Leu-Trp-Pro-OH.CH3CO2H; L-lysyl-L-prolyl-L-glutaminyl-L-leucyl-L-tryptophyl-L-proline acetic acid. Grades: ≥95%. CAS No. 2918771-38-5. Molecular formula: C40H61N9O10. Mole weight: 827.98.
C-Reactive Protein (CRP) 77-82 acetate
C-Reactive Protein (CRP) 77-82 acetate is the 77-82 fragment of C-Reactive Protein, a prototype marker of inflammation and a cardiovascular risk marker that may promote atherosclerosis. Synonyms: H-Val-Gly-Gly-Ser-Glu-Ile-OH.CH3CO2H; L-valyl-glycyl-glycyl-L-seryl-L-alpha-glutamyl-L-isoleucine acetic acid. Grades: ≥95%. CAS No. 2918768-27-9. Molecular formula: C25H44N6O12. Mole weight: 620.66.
CREBtide acetate
CREBtide acetate, a synthetic substrate for PKA (Km = 3.9 μM), is a synthetic peptide consisting of 13 amino acids that is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein). Synonyms: H-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH.CH3CO2H; L-lysyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-seryl-L-arginyl-L-arginyl-L-prolyl-L-seryl-L-tyrosyl-L-arginine acetic acid. Grades: ≥95%. Molecular formula: C75H133N29O21. Mole weight: 1777.07.