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Dopastin
It is produced by the strain of Pseudomonas sp. It has the effect of lowering blood pressure and inhibiting barley germination. Synonyms: NSC252927; N-(2(S)-Nitrosohydroxylamino-3-methylbutyl)crotonamide; (S-(E))-N-(2-(Hydroxynitrosoamino)-3-methylbutyl)-2-butenamide. Grades: 95%. CAS No. 37134-80-8. Molecular formula: C9H17N3O3. Mole weight: 215.25.
DOPG
DOPG is a phosphatidylglycerol in which the phosphatidyl acyl groups are both oleoyl. It has been used to physically stabilize emulsions and suspensions. It is also used in formulations of pulmonary surfactants, intravenous fat emulsions, and oral solutions. Synonyms: Dioleoyl phosphatidylglycerol; 1,2-Dioctadecenoyl-sn-glycero-3-[phospho-rac-(1-glycerol)]; C18:1 phosphatidylglycerol; C18:1 PG; DOPG; 3-{[ (2, 3-dihydroxypropoxy) (hydroxy)phosphoryl]oxy}-2-[ (9Z)-octadec-9-enoyloxy]propyl (9Z)-octadec-9-enoate. Grades: ≥95% by HPLC. CAS No. 62700-69-0. Molecular formula: C42H79O10P. Mole weight: 775.04.
DOTA(allyl ester)3, a protected DOTA derivative, is used for coupling to acid- or base-sensitive compounds. Synonyms: DOTA(OAll)3; 4,7,10-Tri-(allyloxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-yl-acetic acid; 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7-triallyl ester; 2-(4,7,10-tris(2-(allyloxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetic acid; {4,7,10-Tris[2-(allyloxy)-2-oxoethyl]-1,4,7,10-tetraazacyclododecan-1-yl}acetic acid. Molecular formula: C25H40N4O8. Mole weight: 524.61.
DOTAP
DOTAP is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. DOTAP is a good immunomodulator, the antigen presenting capacity of antigen presenting cells can be obviously improved by preparing cationic liposome by packaging polypeptide or protein antigens and the DOTAP, and the DOTAP can activate the antigen presenting cells through a mitogen-activated protein kinase (MAP) pathway to induce specific immune response, unlike the traditional adjuvant which activates the antigen presenting cells through a Toll-like receptor pathway. Synonyms: 1,2-Dioleoyloxy-3-(trimethylammonium)propane; 1,2-Dotap; N,N,N-Trimethyl-2,3-bis((-1-oxo-octadecenyl)oxy)-(Z,Z)-1-propanaminium; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium. CAS No. 113669-21-9. Molecular formula: C42H80NO4. Mole weight: 663.09.
Dowex AG 1-X2
Anion exchange resin. Synonyms: AG 1-X2 Resin.
Doxorubicinone
Cas No. 24385-10-2.
Doxycycline EP Impurity A
Doxycycline EP Impurity A is an impurity of Doxycycline, which is a semisynthetic, broad-spectrum tetracycline antibiotic used in the treatment of infections caused by bacteria and certain parasites. Synonyms: 6-Epidoxycycline; Doxycycline hyclate EP impurity A; Doxycycline monohydrate EP impurity A; 6β-Deoxy-5-hydroxytetracycline; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6S,12aS)-; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, 6-epimer; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α, 4aα, 5α, 5aα, 6β, 12aα)]-; 6-epi-Doxycycline; 6-epi-Oxytetracycline, 6-deoxy-; 6-Epioxytetracycline, 6-deoxy-; epi-Doxycycline; β-6-Deoxy-5-hydroxytetracycline; Doxycycline Related Compound A; Doxycycline USP Related Compound A. Grades: ≥95%. CAS No. 3219-99-6. Molecular formula: C22H24N2O8. Mole weight: 444.43.
Doxycycline EP Impurity B
Meclocycline is a semi-synthetic tetracycline prepared by dehydrating the 6-hydroxyl group of oxytetracycline. It has a wide range of antibacterial and antiprotozoal activities. Meclocycline is an impurity of Doxycycline, which is a semisynthetic, broad-spectrum tetracycline antibiotic used in the treatment of infections caused by bacteria and certain parasites. Uses: Antibiotics, tetracycline. Synonyms: Doxycycline hyclate EP impurity B; Doxycycline monohydrate EP impurity B; 6-Methyleneoxytetracycline; Metacycline; Rondomycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4S,4aR,5S,5aR,12aS)-; (4S,4aR,5S,5aR,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, [4S-(4α, 4aα, 5α, 5aα, 12aα)]-; 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline; 6-Deoxy-6-methylene-6-demethyl-5-hydroxytetracycline; 6-Methylene-5-hydroxytetracycline; 6-Methyleneoxytetracycline; Bialatan; GS 2876; Oxytetracycline, 6-methylene-; Rondomycin; Tri-methacycline. Grades: >98% by HPLC. CAS No. 914-00-1. Molecular formula: C22H22N2O8. Mole weight: 442.42.
Doxycycline hydrochloride
It is produced by the strain of Oxytetracycline or Methacycline. It is regarded as the third generation of tetracycline. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Its antibacterial spectrum is similar to Tetracycline, its antibacterial activity is 2-8 times of Tetracycline, its plasma elimination half-life is as long as 18-22h, and it has little effect on renal function. It can be used for the prevention and treatment of domestic animal respiratory diseases and mixed infection of bacterial diseases when respiratory diseases occur. Uses: Anti-bacterial agents. Synonyms: Doxylin; samecin; 6-deoxy-5-oxytetracycline hydrochloride; novadox; liomycin; retens; Doxycycline HCl; tecacin; mespafin; Doxigalumicina; Doxylin; Deoxy-5-hydroxytetracycline hydrochloride. Grades: >98%. CAS No. 10592-13-9. Molecular formula: C22H25ClN2O8. Mole weight: 480.89.
DP-b 99
DP-b 99 is a zinc and calcium ions chelating agent potentially for the treatment of acute pancreatitis. DP-b99 is a newly developed lipophilic, cell-permeable derivative of BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid), that is under development as a neuroprotectant for the potential treatment of stroke, head trauma and neurological damage associated with coronary artery bypass graft. Synonyms: Glycine, N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-, 1,1'-bis[2-(octyloxy)ethyl] ester; DP-b99; DP-b-99; 2,2'-(((Ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis((2-(2-(octyloxy)ethoxy)-2-oxoethyl)azanediyl))diacetic acid; 1,2-Bis(2-aminophenoxy)ethane-N,N-di(2-octyloxyethyl acetate)-N,N-diacetic acid; N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester; DP-BAPTA-99. Grades: ≥95%. CAS No. 222315-88-0. Molecular formula: C42H64N2O12. Mole weight: 788.96.
(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide, a synthetic somatostatin analogue, is selective for human somatostatin receptor subtype 5 (hsst5) and has similar binding affinity to somatostatin-28, with Kd±SEM values of 1200, 23.5±3.92, 11.05±1.03, >1000 and 0.61±0.36 nM for hsst1, hsst2, hsst3, hsst4 and hsst5, respectively. Synonyms: (N-Me-D-Trp4,Thr8)-Octreotide amide; H-D-Phe-Cys-Phe-N-Me-D-Trp-Lys-Thr-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7); D-phenylalanyl-L-cysteinyl-L-phenylalanyl-N-methyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninamide (2->7)-disulfide. Grades: ≥95% by HPLC. CAS No. 340821-13-8. Molecular formula: C50H67N11O10S2. Mole weight: 1046.26.
D-(+)-Phenyllactic acid, an antibacterial agent excreted by Geotrichum candidum, inhibits a range of gram-positive bacteria in humans and foodstuffs as well as gram-negative bacteria found in humans. Synonyms: D-3-Phenyllactic acid; D-(+)-3-Phenyllactic Acid; (+)-2-Hydroxy-3-phenylpropanoic Acid; (+)-2-Hydroxy-3-phenylpropionic Acid; (+)-β-Phenyllactic Acid; (2R)-2-Hydroxy-3-phenylpropionic Acid; (2R)-3-Phenyl-2-hydroxypropanoic Acid; (R)-2-Hydroxy-3-phenylpropionic Acid; (R)-3-Phenyl-2-hydroxypropanoic Acid; (R)-3-Phenyl-2-hydroxypropionic Acid; (R)-3-Phenyllactic Acid; (R)-Phenyllactic Acid; (R)-α-Hydroxy-3-phenylpropionic Acid; (R)-β-Phenyllactic Acid; D-2-Hydroxy-3-phenylpropionic Acid; D-β-Phenyllactic Acid; β-Phenyl-D-lactic Acid. Grades: ≥95%. CAS No. 7326-19-4. Molecular formula: C9H10O3. Mole weight: 166.17.
(D-Pro7)-Angiotensin I/II (1-7)
(D-Pro7)-Angiotensin I/II (1-7) is a selective antagonist of angiotensin (1-7). Synonyms: DPro7-angiontensin-(1-7); H-Asp-Arg-Val-Tyr-Ile-His-D-Pro-OH; L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-D-proline; L-α-Aspartyl-N5-(diaminomethylene)-L-ornithyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-D-proline. Grades: ≥95%. CAS No. 586962-44-9. Molecular formula: C41H62N12O11. Mole weight: 899.02.
Dregamine
Dregamine is a naturally occurring monoterpene indole alkaloid found in Tabernaemontana. Synonyms: 20-Epitabernemontanine; Tabernaemontanine; Vobasan-17-oic acid, 19,20-dihydro-3-oxo-, methyl ester, (20α)- (9CI). CAS No. 2299-26-5. Molecular formula: C21H26N2O3. Mole weight: 354.44.
Drimendiol
Drimendiol is a polyploid sesquiterpene diol, which is reported to be a quorum sensing inhibitor. Synonyms: Drim-7-ene-11,12-diol; (-)-drim-7-ene-11,12-diol; (-)-11,12-dihydroxy-7-drimene. Grades: >95% by HPLC. CAS No. 34437-62-2. Molecular formula: C15H26O2. Mole weight: 238.37.
Drosophilin E
It is produced by the strain of Drosophila subatrata. Synonyms: cis-Non-4-en-6,8-diinsaeure. CAS No. 505-87-3. Molecular formula: C9H8O2. Mole weight: 148.16.
(D-Ser1)-ACTH (1-24) (human, bovine, rat)
(D-Ser1)-ACTH (1-24) (human, bovine, rat) is a seminal peptide hormone within the scientific community, plays the role of an adrenocorticotropic hormone (ACTH) receptor agonist. Its diverse applications in both research and therapy encompass disorders characterized by adrenal insufficiency, the formidable Cushing's syndrome and an array of conditions impacting the adrenal cortex. Synonyms: (D-Ser1)-Tetracosactide; H-D-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; α1-24-Corticotropin, 1-D-serine-; Proline, D-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-; D-Ser1-Met4-tetracosapeptide; Ba 38522. Grades: ≥95%. CAS No. 18067-65-7. Molecular formula: C136H210N40O31S. Mole weight: 2933.44.
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is the impurity A of the Goserelin. Synonyms: (D-Ser4)-Goserelin; Pyr-His-Trp-D-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2; Goserelin EP Impurity A; Goserelin Impurity 1; (2S)-N-[(2S,5S,8R,11S,14R,17S,20S)-25-Amino-20-({(2S)-2-[(2-carbamoylhydrazino)carbonyl]-1-pyrrolidinyl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-5-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-isobutyl-14-{[(2-methyl-2-propanyl)oxy]methyl}-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxo-2-pyrrolidinecarboxamide; L-pyroglutamyl-L-histidyl-L-tryptophyl-D-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N'-carbamoyl-L-prolinehydrazide. Grades: ≥95%. CAS No. 1926163-39-4. Molecular formula: C59H84N18O14. Mole weight: 1269.41.
(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is the impurity L of the Goserelin. Synonyms: (D-Leu7)-Goserelin; Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-D-Leu-Arg-Pro-Azagly-NH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-D-leucyl-L-arginyl-N'-carbamoyl-L-prolinehydrazide; Goserelin EP Impurity L; Goserelin Impurity 12; (2S)-N-[(2S,5S,8S,11S,14R,17R,20S)-25-Amino-20-({(2S)-2-[(2-carbamoylhydrazino)carbonyl]-1-pyrrolidinyl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-4-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-isobutyl-14-{[(2-methyl-2-propanyl)oxy]methyl}-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxo-2-pyrrolidinecarboxamide. Grades: ≥90%. CAS No. 1926163-38-3. Molecular formula: C59H84N18O14. Mole weight: 1269.41.
D-Threoninamide
Cas No. 2280-40-2. Molecular formula: C4H10N2O2. Mole weight: 118.1.
[D-Trp7,9,10]-Substance P acetate is an analogue of substance P. Substance P inhibits ion conductance through nicotinic acetylcholine receptors. Molecular formula: C81H109N21O15S. Mole weight: 1648.93.
[D-Trp8]-γ-MSH acetate
[D-Trp8]-γ-MSH acetate is a selective melanocortin 3 (MC3) receptor agonist (IC50 = 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors, respectively). It displays antiinflammatory efficacy in mice bearing a non-functional MC1R (recessive yellow e/e mouse) and these effects are abrogated in the presence of the HO-1 inhibitor ZnPPIX. Synonyms: CTX-1100 acetate; L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycine acetate; H-Tyr-Val-Met-Gly-His-Phe-Arg-D-Trp-Asp-Arg-Phe-Gly-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C76H103N21O18S. Mole weight: 1630.82.
[D-Trp8]-γ-MSH TFA
[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). It displays anti-inflammatory efficacy. Synonyms: CTX-1100 trifluoroacetate; L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycine trifluoroacetate; H-Tyr-Val-Met-Gly-His-Phe-Arg-D-Trp-Asp-Arg-Phe-Gly-OH.TFA. Grades: ≥95%. Molecular formula: C76H100F3N21O18S. Mole weight: 1684.79.
(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH is the impurity F of the Goserelin. Synonyms: (D-Tyr5)-Goserelin; Pyr-His-Trp-Ser-D-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-D-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N'-carbamoyl-L-prolinehydrazide; Goserelin Impurity 6; Goserelin EP Impurity F; (2S)-N-[(2S,5S,8S,11R,14R,17S,20S)-25-Amino-20-({(2S)-2-[(2-carbamoylhydrazino)carbonyl]-1-pyrrolidinyl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-5-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-isobutyl-14-{[(2-methyl-2-propanyl)oxy]methyl}-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxo-2-pyrrolidinecarboxamide. Grades: ≥95%. CAS No. 1426173-74-1. Molecular formula: C59H84N18O14. Mole weight: 1269.41.
Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro. Synonyms: (+)-duocarmycin SA; Antibiotic DC113; methyl (1R, 12S)-7-oxo-10-(5, 6, 7-trimethoxy-1H-indole-2-carbonyl)-5, 10-diazatetracyclo[7.4.0.01, 12.02, 6]trideca-2(6), 3, 8-triene-4-carboxylate. Grades: 98.0%. CAS No. 130288-24-3. Molecular formula: C25H23N3O7. Mole weight: 477.47.
Dustanin
Dustanin is a hopane isolated from Aschersonia. Synonyms: 15alpha,22-dihydroxyhopane; Hopane-15α,22-diol. CAS No. 3607-96-3. Molecular formula: C30H52O2. Mole weight: 444.73.
D-Valinamide
Cas No. 32526-16-2. Molecular formula: C5H12N2O. Mole weight: 116.2.
DX600 TFA
DX600 TFA is an inhibitor of angiotensin-converting enzyme 2 (ACE2) and does not cross-react with ACE. Synonyms: Glycinamide, N-acetylglycyl-L-α-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-α-aspartyl-L-prolyl-L-α-glutamylglycylglycyl-, cyclic (6?17)-disulfide, trifluoroacetate salt (1:1); Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2.TFA (Disulfide bridge: Cys6-Cys17); N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide trifluoroacetic acid. Grades: ≥95%. Molecular formula: C123H169F3N32O39S2. Mole weight: 2841.01.
Dynorphin A 1-10 acetate
Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide that binds to the extracellular loop 2 of the κ-opioid receptor. It also blocks the NMDA activation current with an IC50 of 42.0 μM. Synonyms: H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-OH.CH3CO2H; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-proline acetic acid; 1-10-Dynorphin A (swine) acetate; α-Neoendorphin (pig), 7-L-arginine-8-L-isoleucine-9-L-arginine-10-L-proline-, acetate (1:1); Porcine dynorphin A (1-10) acetate. Grades: ≥95%. Molecular formula: C59H95N19O14. Mole weight: 1294.53.
Dynorphin A (1-13) amide
Dynorphin A (1-13) amide is an antagonist of human MC1, MC3 and MC4 receptors. Synonyms: Dynorphin A (1-13), amide, porcine; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2; L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide; Linear Dyn A-(1-13)NH2; L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N5-(diaminomethylene)-L-ornithyl-N5-(diaminomethylene)-L-ornithyl-L-isoleucyl-N5-(diaminomethylene)-L-ornithyl-L-prolyl-L-lysyl-L-leucyl-L-lysinamide. Grades: ≥95%. CAS No. 79515-34-7. Molecular formula: C75H127N25O14. Mole weight: 1602.97.
Dynorphin A acetate
Dynorphin A acetate is a heptadecapeptide derived from the cleavage of prodynorphin and found widely distributed in the central nervous system. It acts as an endogenous kappa receptor agonist with nanomolar binding affinity. It also activates the human novel opioid receptor-like receptor of ORL1. It is resistant to enzymatic degradation and may have antinociceptive functions. Synonyms: Dynorphin (1-17) acetate; Dynorphin A (human, pig, rat, Bos taurus) acetate; Porcine dynorphin (1-17) acetate; L-Glutamine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-isoleucyl-L-arginyl-L-prolyl-L-lysyl-L-leucyl-L-lysyl-L-tryptophyl-L-α-aspartyl-L-asparaginyl-, acetate; H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C101H159N31O25. Mole weight: 2207.58.
(E)-3-(5-Nitro-2-furyl)acrylaldehyde
(E)?-3-(5-Nitrofuran-2-yl)?acrylaldehyde can be used as reactant/reagent for starting material and preparation of hydrazone and diacylhydrazine derivatives as ERAD inhibitors useful in the treatment of diseases. Synonyms: (E)-3-(5-Nitrofuran-2-yl)acrylaldehyde. Grades: 95%. CAS No. 52661-56-0. Molecular formula: C7H5NO4. Mole weight: 167.12.
(E)-3-O-Methyl Entacapone
An impurity of Entacapone. Entacapone is a medication commonly used in combination with other medications for the treatment of Parkinson's disease. Synonyms: (2E)-2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamide. Grades: > 95%. CAS No. 857629-78-8. Molecular formula: C15H17N3O5. Mole weight: 319.32.
E-76, a potent anticoagulant, is an inhibitor of coagulation factor VIIa. It acts by binding to an exosite on the VIIa protease domain and non-competitively inhibits the activation of factor X and amide hydrolytic activity. Synonyms: E-76; Acetyl-ALCDDPRVDRWYCQFVEG-amide; Ac-Ala-Leu-D-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH2 (Disulfide bridge: Cys3-Cys13); N-acetyl-L-alanyl-L-leucyl-D-cysteinyl-L-alpha-aspartyl-L-alpha-aspartyl-L-prolyl-L-arginyl-L-valyl-L-alpha-aspartyl-L-arginyl-L-tryptophyl-L-tyrosyl-L-cysteinyl-L-glutaminyl-L-phenylalanyl-L-valyl-L-alpha-glutamyl-glycinamide (3->13)-disulfide. Grades: ≥95% by HPLC. CAS No. 1926163-13-4. Molecular formula: C97H139N27O29S2. Mole weight: 2211.47.
9-oxononyl (E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-((3-hydroxy-4,5-dimethyltetrahydrofuran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoate is an impurity of Mupirocin, which is a carboxylic acid bacteriostatic/bactericidal antibiotic. Synonyms: Mupirocin USP Impurity 4; 9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-((3-hydroxy-4,5-dimethyltetrahydrofuran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyloxy)nonanoic Acid. Grades: 98%. Molecular formula: C26H44O8. Mole weight: 484.62.
EAK16-II
EAK16-II is a self-assembled peptide that can form a stable β-sheet structure and can be used as a carrier or matrix for cell culture. Synonyms: Ac-Ala-Glu-Ala-Glu-Ala-Lys-Ala-Lys-Ala-Glu-Ala-Glu-Ala-Lys-Ala-Lys-NH2; L-Lysinamide, N-acetyl-L-alanyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-alanyl-L-lysyl-L-alanyl-L-α-glutamyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-alanyl-. Grades: ≥95%. CAS No. 157675-61-1. Molecular formula: C70H121N21O25. Mole weight: 1656.84.
Ebecryl 3708 resin
Ebecryl 3708 resin is a modified bisphenol A epoxy bisacrylate with low viscosity and excellent curing reaction. Ebecryl 3708 resin films cured by ultraviolet light (UV) or electron beam (EB) show good flexibility, high gloss, toughness and excellent impact resistance. It can be used in clear coatings for paper, wood, flexible and rigid plastics, topcoats for wood and metal trim vehicles, adhesives for paper or film laminating, and lithography and screen ink vehicles.
Ebelactone B
It is produced by the strain of Streptomyces aburaviensis. It has the inhibitory effect on Esterases (IC50 is 0.00035 μg/mL), Pancreatic lipase (IC50 is 0.0008 μg/mL) and Cutinase on fungal cells. Synonyms: 2-Oxetanone, 3-ethyl-4-(8-hydroxy-1,3,5,7,9-pentamethyl-6-oxo-3-undecenyl)-, (3S-(3-alpha,4-beta(1R*,3E,5S*,7R*,8S*,9S*)))-; Ebelactone; Nsc 335651. CAS No. 76808-15-6. Molecular formula: C21H36O4. Mole weight: 352.51.
Ebenatide
Ebenatide is a long-acting glucagon-like peptide-1 recceptor agonist (GLP-1RA). Ebenatide is undergoing the clinical trial for the treatment of type 2 diabetes mellitus (T2DM).
EcAMP3
EcAMP3, a plant hairpin-like defense polypeptide isolated from the seeds of latent barnyard grass (Echinochloa crusgalli L.), has in vitro antifungal and antibacterial activities. Synonyms: H-Gly-Ala-Asp-Arg-Cys-Arg-Glu-Arg-Cys-Glu-Arg-Arg-His-Arg-Gly-Asp-Trp-Gln-Gly-Lys-Gln-Arg-Cys-Leu-Met-Glu-Cys-Arg-Arg-Arg-Glu-Gln-Glu-Glu-Asp-OH (Disulfide bridge: Cys5-Cys27, Cys9-Cys23). Grades: ≥95%. CAS No. 2243219-65-8. Molecular formula: C172H282N72O57S5. Mole weight: 4430.91.
Echinocarpic acid
It has been isolated from the lichen Pamelia norcrambidiocarpa together with atranorin and chloroatranorin. Synonyms: Benzoic acid, 2,4-dihydroxy-3,6-dimethyl-, (1,3-dihydro-1,4-dihydroxy-6-methoxy-3-oxo-5-isobenzofuranyl)methyl ester; 1',4'-dihydroxy-6'-methoxy-3'-oxo-1',3'-dihydroisobenzofuran-5'-ylmethyl 2,4-dihydroxy-3,6-dimethylbenzoate. CAS No. 79586-50-8. Molecular formula: C19H18O9. Mole weight: 390.34.
Echinosporin
It is produced by the strain of Bacillus brevis Vm4, Streptomyces echinos porus MK-213. It has weak anti-gram-positive bacteria and tumor activity. Synonyms: (1S,4aS,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-8-oxo-1,5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide; (-)-Echinosporin; Antibiotic XK 213; NSC 357683; XK 213; [1S-(1α, 4aβ, 5β, 7aβ)]-1, 4a, 5, 7a-Tetrahydro-5-hydroxy-8-oxo-1, 5-(epoxymethano)cyclopenta[c]pyran-3-carboxamide. Grades: >98%. CAS No. 79127-35-8. Molecular formula: C10H9NO5. Mole weight: 223.18.
(E, E, E)-2,4,6-Nonatrienal
(2E,4E,6E)-2,4,6-Nonatrienal is an unsaturated aldehyde that is a natural volatile constituent of aggregation pheromones produced by male flea beetles. Synonyms: (2E,4E,6E)-2,4,6-Nonatrienal; (E,E,E)-2,4,6-Nonatrienal; (E,E,E)-Nona-2,4,6-trienal; trans,trans,trans-Nona-2,4,6-trienal. Grades: > 95%. CAS No. 57018-53-8. Molecular formula: C9H12O. Mole weight: 136.2.
Efpeglenatide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA). Efpeglenatide has been developed as an injection for type 2 diabetes mellitus (T2DM). Synonyms: efpeg. CAS No. 1296200-77-5.
EGF Receptor (985-996) (human)
EGF Receptor (985-996) (human) exists on the cell surface and is activated by the binding of its specific ligands. EGFR belongs to the tyrosine kinase receptor (RTK) ErbB family. Synonyms: L-Glutamine, L-α-aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-; L-Glutamine, N2-[1-[N-[N-[N-[N-[N-[N-[N-[N-(N-L-α-aspartyl-L-valyl)-L-valyl]-L-α-aspartyl]-L-alanyl]-L-α-aspartyl]-L-α-glutamyl]-L-tyrosyl]-L-leucyl]-L-isoleucyl]-L-prolyl]-; L-α-Aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-L-glutamine; H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH; Epidermal Growth Factor Receptor Peptide. Grades: ≥95%. CAS No. 96249-43-3. Molecular formula: C61H93N13O23. Mole weight: 1376.46.
ELA-14 (human) acetate
ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grades: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09.
Elaiophylin
It is produced by the strain of Streptomyces melanosporofacien. It has the activity of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as insect repellent and growth promoter for ruminants. Elaiophylin is an autophagy inhibitor, which exerts antitumor activity as a single agent in ovarian cancer cells. Synonyms: Azalomycin B; Salbomycin; Azalomycin B; Antibiotic 5001B; Antibiotic 56-62; Elaiofilin. Grades: ≥95%. CAS No. 37318-06-2. Molecular formula: C54H88O18. Mole weight: 1025.26.
Elamipretide triacetate
Elamipretide triacetate is an aromatic-cationic tetrapeptide that targets the mitochondrial intima and is an inhibitor of cardiolipin peroxidase. It easily penetrates cell membranes and has been used in therapeutic trials investigating Leber's Hereditary Optic Neuropathy. Synonyms: L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-, acetate (1:3); SS-31 triacetate; H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2.3CH3CO2H; D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide acetic acid; D-Arg-2',6'-Dmt-Lys-Phe-NH2 triacetate. Grades: ≥95%. CAS No. 1849610-71-4. Molecular formula: C32H49N9O5.3C2H4O2. Mole weight: 819.95.
Eledoisin Related Peptide 2TFA
Eledoisin Related Peptide 2TFA, a substance P analogue, is a tachykinin receptor ligand. Synonyms: H-Lys-Phe-Ile-Gly-Leu-Met-NH2.2TFA; L-lysyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid. Grades: ≥95%. CAS No. 2918768-25-7. Molecular formula: C34H58N8O6S.2C2HF3O2. Mole weight: 934.99.
Eledoisin trifluoroacetate
Eledoisin was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi. It is a potent natural tachykinin receptor ligand, and a potent vasodilator that increases capillary permeability. Synonyms: H-Pyr-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2.TFA; L-pyroglutamyl-L-prolyl-L-seryl-L-lysyl-L-alpha-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucyl-glycyl-L-leucyl-L-methioninamide trifluoroacetic acid; Eledoisin, mono(trifluoroacetate) (salt); 5-Oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide trifluoroacetate; Eledoisin, trifluoroacetate (1:1). Grades: ≥95%. CAS No. 10129-92-7. Molecular formula: C54H85N13O15S.C2HF3O2. Mole weight: 1302.42.
Elsamitrucin
Elsamitrucin is produced by the strain of Actinomycetes J904-21. It has strong anti-tumor activity of mouse tumor cells such as leukemia P388, L1210 and melanoma B16, and its anti-tumor activity is 10-30 times stronger than Chartreusin. Uses: Antibiotics, antineoplastic. Synonyms: Elsamicin A. Grades: >95%. CAS No. 97068-30-9. Molecular formula: C33H35NO13. Mole weight: 653.63.