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10,11-Dihydro-10,11-Dihydroxy Carbamazepine (Mixture of Isomers)
An impurity of Carbamazepine. Grades: > 95%. CAS No. 1217528-81-8. Molecular formula: C15H14N2O3. Mole weight: 270.29.
10,11-Dihydro Carbamazepine
10,11-Dihydro Carbamazepine is a dihydro impurity of Carbamazepine. Uses: A dihydro impurity of carbamazepine (c175840). Synonyms: 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide; GP 26-301; Carbamazepine EP Impurity A. CAS No. 3564-73-6. Molecular formula: C15H14N2O. Mole weight: 238.28.
10-(2,2,2-Trichloroethyloxycarbonyl)-10-deacetylbaccatin III
10-(2,2,2-Trichloroethyloxycarbonyl)-10-deacetylbaccatin III is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C32H37Cl3O12. Mole weight: 719.99.
10-Chloro Carbamazepine is a derivative of Carbamazepine, which is used in treatment of pain associated with trigeminal neuralgia. Synonyms: 10-Chloro-5H-dibenz[b,f]azepine-5-carboxamide; CGP 9055. CAS No. 59690-92-5. Molecular formula: C15H11ClN2O. Mole weight: 270.71.
10-Deacetyl-13-Oxo-Baccatin III
13-Oxo-10-deacetyl Baccatin III is a novel stable derivative of 10-Deacetylbaccatin III with antitumor and antimitotic activity. Synonyms: (2aR,4S,4aS,6R,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,4,4a,10,11,12,12a,12b-octahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-5,9(3H,6H)-dione; 10-Deacetyl-13-oxobaccatin III. Grades: > 95%. CAS No. 92950-42-0. Molecular formula: C29H34O10. Mole weight: 542.59.
2-Debenzoyl-2-tigloyl 10-Deacetyl Baccatin III is a new analog of 10-Deacetylbaccatin III. Synonyms: (2E)-2-Methyl-2-butenoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)- 12b-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-12-yl Ester; 2-Debenzoyl-2-t. Grades: > 95%. CAS No. 171926-87-7. Molecular formula: C27H38O10. Mole weight: 522.6.
10-Deacetyl Cephalomannine
10-Deacetyl Cephalomannine is a derivative of Cephalomannine. Synonyms: (αR,βS)-α-Hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-meth. Grades: > 95%. CAS No. 76429-85-1. Molecular formula: C43H51NO13. Mole weight: 789.88.
10-Deacetyl Paclitaxel Ethyl Analogue
An impurity of Paclitaxel which is the first taxane in clinical trials as a chemotherapy medicine. Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-4,6,11-trihydroxy-9-(((2R,3S)-2-hydroxy-3-phenyl-3-propionamidopropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate; 10-Deacetyl-3'-debenzoyl-3'-propanoylpaclitaxel. Grades: > 95%. CAS No. 173101-59-2. Molecular formula: C41H49NO13. Mole weight: 763.85.
10-Deacetyl Paclitaxel Propyl Analogue
An impurity of Paclitaxel which induces the expression of the gene for tumor necrosis factor &alpha. Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-butyramido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate; 10-Deacetyl-3'-debenzoyl-3'-butanoylpaclitaxel. Grades: > 95%. CAS No. 173101-47-8. Molecular formula: C42H51NO13. Mole weight: 777.87.
10-Hydroxy Amitriptyline Oxalate
Amitriptyline Related Compound. Synonyms: 5-[3-(Dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol Oxalate. Grades: > 95%. CAS No. 1246833-15-7. Molecular formula: C20H23NO. C2H2O4. Mole weight: 383.44.
10-Hydroxy Protriptyline
A metabolite of Protriptyline. Protriptyline is a tricyclic antidepressant for the treatment of depression and ADHD. Synonyms: 5-[3-(Methylamino)propyl]-5H-dibenzo[a,d]cyclohepten-10-ol; 10-Hydroxy-N-methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine. Grades: > 95%. CAS No. 27462-57-3. Molecular formula: C19H23NO. Mole weight: 281.4.
10-Methoxy Carbamazepine
Intermediate in the preparation of dibenzazepine derivatives. Synonyms: 10-Methoxy-5H-dibenz[b,f]azepine-5-carboxamide. Grades: > 95%. CAS No. 28721-09-7. Molecular formula: C16H14N2O2. Mole weight: 266.3.
10-Methoxyiminostilbene
an impurity of Carbamazepine. Synonyms: 10-Methoxy-5H-dibenz[b,f]azepine. Grades: > 95%. CAS No. 4698-11-7. Molecular formula: C15H13NO. Mole weight: 223.28.
10-O-Deacetyl-7-Acetoacetyl Paclitaxel is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C49H53NO15. Mole weight: 895.94.
(10R,12S) Caspofungin
(10R,12S) Caspofungin is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H88N10O15. Mole weight: 1093.31.
11,13-Di-cis-retinoic Acid
11,13-Di-cis-retinoic Acid is an impurity of Isotretinoin as per European Pharmacopoeia. Synonyms: (11-cis,13-cis)-Retinoic Acid; Isotretinoin EP Impurity C. CAS No. 3555-80-4. Molecular formula: C20H28O2. Mole weight: 300.44.
1-[1-(4-Benzyloxyphenyl)-2-dimethylaminoethyl]-cyclohexanol is a reactant used in the synthesis of O-desmethylvenlafaxine succinate. Synonyms: 1-[2- (Dimethylamino) -1-[4- (phenylmethoxy) phenyl]ethyl]cyclohexanol. CAS No. 93413-61-7. Molecular formula: C23H31NO2. Mole weight: 353.51.
11β,17α-Dihydroxy-17-[(phosphonooxy)methyl]-D-homoandrosta-1,4-diene-3,17a-dione is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: 11-beta,17-alfa-Dihydroxy-17-[(phosphonooxy)methyl]-D-homoandrosta-1,4-diene-3,17a-dione; Prednisolone Sodium Phosphate USP Impurity A. Grades: > 95%. Molecular formula: C21H29O8P. Mole weight: 440.42.
(11β,17Z)-11-Hydroxy-3-oxo-pregna-1,4,17(20)-trien-21-al 20-O-Phosphate Disodium Salt
(11β,17Z)-11-Hydroxy-3-oxo-pregna-1,4,17(20)-trien-21-al 20-O-Phosphate Disodium Salt is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: Prednisolone Impurity. Molecular formula: C21H25Na2O7P. Mole weight: 466.37.
(11β,17Z)-20-(Acetyloxy)-11-hydroxy-3-oxopregna-1,4,17(20)-trien-21-al, is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: (11?,17Z)-20-(Acetyloxy)-11-hydroxy-3-oxopregna-1,4,17(20)-trien-21-al; 118866-09-4. CAS No. 118866-09-4. Molecular formula: C23H28O5. Mole weight: 384.46.
(11β)-9-Fluoro-11-hydroxy-16-methyl-3-oxo-androsta-1,4,16-triene-17-carboxylic Acid is one of Clobetasol propionate impurities. Clobetasol propionate is a glucocorticoid that induces monooxygenase activity in vivo. It alters the structure of tight junctions in epidermis and smoothened hedgehog pathway receptor agonist. It can be used as an anti-inflammatory, immunosuppressive and antimitotic agent. Active in vivo. CAS No. 59861-00-6. Molecular formula: C21H25FO4. Mole weight: 360.42.
11β-Hydroxy-3-oxo-androsta-1,4-diene-17β-carboxylic Acid is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. CAS No. 75448-51-0. Molecular formula: C20H26O4. Mole weight: 330.42.
11β-Hydroxy-6α-methyl-1,4-androstadiene-3,17-dione is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: (6α,11β)-11-Hydroxy-6-methylandrosta-1,4-diene-3,17-dione; 1β-Hydroxy-6α-methylandrosta-1,4-diene-3,17-dione; Methylprednisolone EP Impurity C. CAS No. 61919-52-6. Molecular formula: C20H26O3. Mole weight: 314.42.
11-beta-Prostaglandin E1
11β-Prostaglandin E1 (11β-PGE1) is an epimerized form of PGE1 at the C-11 position. 11β-PGE1 is a less potent isomer of PGE1. Prostaglandin E1 is a naturally occurring prostaglandin. It is used to treat erectile dysfunction. Synonyms: 9-oxo-11β,15S-dihydroxy-prost-13E-en-1-oic acid. Grades: > 95%. CAS No. 24570-01-2. Molecular formula: C20H34O5. Mole weight: 354.49.
11-epi-Prednisolone-21-Disodium Phosphate
11-epi-Prednisolone-21-Disodium Phosphate is an impurity of Prednisolone which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Molecular formula: C21H27O8PNa2. Mole weight: 484.39.
1,1'-[Iminobis(carbonimidoyliminohexane-6,1-dil)]bis[5-(4-chlorophenyl)biguadine] is one of chlorhexidine impurities. Chlorhexidine is a disinfectant and topical anti-infective agent for reduction of pocket depth in patients with adult periodontitis. Synonyms: Chlorhexidine Impurity H. Molecular formula: C30H47Cl2N15. Mole weight: 688.70.
11-(N-Hydroxy) Loratadine 1-Oxide
11-(N-Hydroxy) Loratadine 1-Oxide is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Molecular formula: C19H19ClN2O2. Mole weight: 342.82.
An isomer of Trandolaprilat, which is an impurity of Trandolapril. Trandolaprilat is an angiotensin converting enzyme inhibitor. Synonyms: 1H-Indole-2-carboxylicacid, 1-[2-[(1-carboxy-3-phenylpropyl)amino]-1-oxopropyl]octahydro-; 1-(2-((1-Carboxy-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid; SCHEMBL678354; DTXSID90868979; 1H-Indol-2-carboxylic acid, 1-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)octahydro-; 1-{2-[ (1-carboxy-3-phenylpropyl) amino]propanoyl}octahydro-1H-indole-2-carboxylic acid (non-preferred name); FT-0687175. CAS No. 83601-86-9. Molecular formula: C22H30N2O5. Mole weight: 402.491.
1,2,3,4,7,8,9-Heptachlorodibenzofuran
1,2,3,4,7,8,9-Heptachlorodibenzofuran is a common environmental pollutant. Synonyms: 1,2,3,4,7,8,9-HPCDF; 1,2,3,4,7,8,9-HCDF; Heptachlorodibenzofuran, 1,2,3,4,7,8,9; 1,2,3,4,7,8,9-CDF; F 134; PCDF 134. Grades: > 95%. CAS No. 55673-89-7. Molecular formula: C12H1Cl7O. Mole weight: 409.31.
1,2,3,6,7,8-Hexachlorodibenzofuran
1,2,3,6,7,8-Hexachlorodibenzofuran is a toxic polychlorinated dibenzofurans (PCDD/F), detected in domestic meat and poultry. It can be used as purified standards for analytical, toxic, and biological studies of these environmental contaminants. Synonyms: 1,2,3,6,7,8-HXCDF; 1,2,3,6,7,8-HCDF; Hexachlorodibenzofuran, 1,2,3,6,7,8-; 2,3,4,7,8,9-Hexachlorodibenzofuran; F 121; PCDF 121. Grades: > 95%. CAS No. 57117-44-9. Molecular formula: C12H2Cl6O. Mole weight: 374.87.
1,2,3,7,8,9-Hexachlorodibenzofuran
1,2,3,7,8,9-Hexachlorodibenzofuran is a common environmental pollutant. Synonyms: 1,2,3,7,8,9-HCDF; 1,2,3,7,8,9-HXCDF; Hexachlorodibenzofuran, 1,2,3,7,8,9-; PCDF 122; 1,2,3,7,8,9-HxCDF; PCDF 122. Grades: > 95%. CAS No. 72918-21-9. Molecular formula: C12H2Cl6O. Mole weight: 374.87.
1,2,4-Triazole-3-carboxylic acid
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: 1H-1,2,4-Triazole-3-carboxylic acid; s-Triazole-3-carboxylic acid; 4H-1,2,4-Triazole-3-carboxylic acid; NSC 165527; NSC 202574; Ribavirin EP Impurity C; Ribavirin Impurity C. Grades: ≥95%. CAS No. 4928-87-4. Molecular formula: C3H3N3O2. Mole weight: 113.07.
(1,2,6,7,-Tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Ramelteon. Synonyms: 2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile; Dihydro-1H-indeno[5,4-B]furan-8(2H)-ylidene)acetonitrile. Grades: >95%. CAS No. 221530-44-5. Molecular formula: C13H11NO. Mole weight: 197.23.
1-(2-aminoethyl)-6-methoxyindan
1-(2-aminoethyl)-6-methoxyindan is an impurity of Ramelteon. Ramelteon is a potent and selective agonist at melatonin MT1/MT2 receptor. Ramelteon is a sleep agent medication used to treat sleeplessness (insomnia). Uses: Intermediate in the production of ramelteon. Synonyms: 2,3-Dihydro-6-methoxy-1H-indene-1-ethanamine; rac-2,3-Dihydro-6-methoxy-1H-indene-1-ethanamine. Grades: 95%. CAS No. 108048-37-9. Molecular formula: C12H17NO. Mole weight: 191.27.
An impurity of Prasugrel.Prasugrel is a platelet inhibitor. It can be used to prevent formation of blood clots. Grades: > 95%. CAS No. 79927-21-2. Molecular formula: C8H10N2OS. Mole weight: 182.25.
12-Fluoro Dihydroloratadine
12-Fluoro Dihydroloratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(8-Chloro-10,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-yl)-4-fluoro-ethyl Ester 1-Piperidinecarboxylic Acid; 1-Piperidinecarboxylic acid, 4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-4-fluoro-, ethyl ester; 1-Piperidinecarboxylic acid, 4-(8-chloro-10,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-yl)-4-fluoro-, ethyl ester; Ethyl 4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-4-fluoropiperidine-1-carboxylate. Grades: ≥95%. CAS No. 125743-79-5. Molecular formula: C22H24ClFN2O2. Mole weight: 402.89.
1-(2-Furoyl)piperazine
One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergicblocker. Synonyms: furan-2-yl(piperazin-1-yl)methanone. Grades: > 95 %. CAS No. 40172-95-0. Molecular formula: C9H12N2O2. Mole weight: 180.20.
12-Hydoxy Loratadine
12-Hydoxy Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Molecular formula: C22H25ClN2O3. Mole weight: 400.90.
1-(2-Methoxyphenoxy)-3-chloro-2-propanol is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Synonyms: 1-chloro-3-(2-methoxyphenoxy)-2-Propanol; 1-chloro-3-(o-methoxyphenoxy)-2-Propanol (6CI,8CI); 1-Chloro-3-(2-methoxyphenoxy)-2-propanol; 1-Chloro-3-(o-methoxyphenoxy)-2-propanol; 2-Hydroxy-3-(2-methoxyphenoxy)propyl chloride; Ranolazine Impurity 7. Grades: > 98%. CAS No. 25772-81-0. Molecular formula: C10H13ClO3. Mole weight: 216.66.
1-(2-Pyrimidyl)piperazine
The major metabolite of Tandospirone. Synonyms: 2-piperazin-1-ylpyrimidine. Grades: > 95 %. CAS No. 20980-22-7. Molecular formula: C8H12N4. Mole weight: 164.21.
13,14-Anhydro-10-desacetyl Baccatin
13,14-Anhydro-10-desacetyl Baccatin is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: Docetaxel Impurity 24. CAS No. 1217248-58-2. Molecular formula: C29H34O9. Mole weight: 526.57.
13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III
13-{[(3-N-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(triethylsilyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-{(3xi,5beta,7alpha,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-[(triethylsilyl)oxy]-5,20-epoxytax-11-en-13-yl} 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grades: 98%. CAS No. 143527-71-3. Molecular formula: C54H73NO15Si. Mole weight: 1004.24.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7α-dihydroxy Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7α-dihydroxy Baccatin III is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C48H59NO16. Mole weight: 905.98.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7β-dihydroxy Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-6α,7β-dihydroxy Baccatin III is one of Paclitaxel intermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Molecular formula: C48H59NO16. Mole weight: 905.98.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III is one of Paclitaxel precursors. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: (4S,5R)-2,2-Dimethyl-4-phenyl-3,5-oxazolidinedicarboxylic Acid 5-[(2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-6, 12b-Bis(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-11-hydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-4-[[(2, 2, 2-trichloroethoxy)carbonyl]oxy]-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl] 3-(1,1-dimethylethyl) Ester; 5-[(3xi,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-9-oxo-7-{[(2,2,2-trichloroethoxy)carbonyl]oxy}-5,20-epoxytax-11-en-13-yl] 3-tert-butyl (4S,5R)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate. Grades: > 98%. CAS No. 143527-73-5. Molecular formula: C51H60Cl3NO17. Mole weight: 1065.38.
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl} Δ6,7-Baccatin III
13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl} Δ6,7-Baccatin III is one of Paclitaxelintermediates. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: N-Desbenzoyl-N-tert-butoxycarbonyl-N,O-isopropylidene-6,7-dehydro Taxol; N-Desbenzoyl-N-tert-butoxycarbonyl-N,O-isopropylidene-6,7-dehydro Paclitaxel. Molecular formula: C48H57NO14. Mole weight: 871.96.
An impurity of Nebivolol, which selectively inhibits β1-adrenoceptor with IC50 of 0.12 nM. Synonyms: 1-(3,4-dihydro-2H-chromen-2-yl)-2-(methylamino)ethanol. Grades: > 95%. Molecular formula: C12H17NO2. Mole weight: 207.27.
1,3,5-triazine-2,4-diamine
Related product of Decitabine. Synonyms: 1,3,5-triazine-2,4-diamine; 1,3,5-triazine-2,4-diamine. Grades: > 95 %. CAS No. 504-08-5. Molecular formula: C3H5N5. Mole weight: 111.108.
1,3-Bis(6-chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C25H14Cl2F4N2O. Mole weight: 505.29.
1-(3-Carboxypropyl)-3,7-dimethylxanthine
1-(3-Carboxypropyl)-3,7-dimethylxanthine is a metabolite of Pentoxifylline. Synonyms: 2,3,6,7-Tetrahydro-3,7-dimethyl-2,6-dioxo-1H-purine-1-butanoic Acid; 3,6-Dihydro-3,7-dimethyl-2,6-dioxopurine-1(2H)-butyric Acid; 1-(3-Carboxypropyl)theobromine; 1-(3'-Carboxypropyl)-3,7-dimethylxanthine; 3,7-Dimethyl-1-(3-carboxypropyl)xanthine. Grades: > 95%. CAS No. 6493-7-8. Molecular formula: C11H14N4O4. Mole weight: 266.26.
One of the impurities of Trazodone, which has been found to be effective as an antidepressant agent. Synonyms: 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine; hydrochloride. CAS No. 52605-52-4. Molecular formula: C13H18Cl2N2 ยท HCl. Mole weight: 309.66.
1-(3-chlorophenyl)-piperazine (m-CPP)
meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class. It was initially developed in the late-1970s and used in scientific research before being sold as a designer drug in the mid-2000s.[1][2] It has been detected in pills touted as legal alternatives to illicit stimulants in New Zealand and pills sold as "ecstasy" in Europe and the United States. Uses: Serotonin receptor agonists. Synonyms: Piperazine, 1-(3-chlorophenyl)-; Piperazine, 1-(m-chlorophenyl)-; 1-(m-Chlorophenyl)piperazine; 4-(3-Chlorophenyl)piperazine; m-CPP; mCPP (pharmaceutical); N-(3-Chlorophenyl)piperazine; N-(m-Chlorophenyl)piperazine; NSC 49307. Grades: ≥95%. CAS No. 6640-24-0. Molecular formula: C10H13ClN2. Mole weight: 196.68.
1,3''-Di-HABA Kanamycin A Sulfate
1,3''-Di-HABA Kanamycin A Sulfate is a synthetic byproduct of Amikacin. Amikacin is an antibacterial compound used in the treatment of diseases and illnesses arising from gram-negative bacterium. Synonyms: O-6-Amino-6-deoxy-α-D-glucopyranosyl-(1?4)-O-[3-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-3-deoxy-α-D-glucopyranosyl-(1?6)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D-streptamine Sulfate; 1,3''-Di-N-(L-4-amino-2-hydroxybutyryl) Kanamycin A Sulfate. Grades: 95%. Molecular formula: C26H50N6O15.xH2SO4. Mole weight: 686.70 (free base).
1,3-Dimethylbarbituric acid
1,3-Dimethyl Barbituric acid is a derivative of Barbituric acid. Barbituric acid is mainly used as as a central nervous system depressant. Synonyms: 1,3-dimethyl-1,3-diazinane-2,4,6-trione. Grades: 98%. CAS No. 769-42-6. Molecular formula: C6H8N2O3. Mole weight: 156.14.
1,3-Diphenyl-1,3-propanedione
Dibenzoylmethan is a kind of aromatic compound ahd has been found to restrain tumorigenesis in mice. Synonyms: 1,3-diphenylpropane-1,3-dione. CAS No. 120-46-7. Molecular formula: C15H12O2. Mole weight: 224.25.
1-(3-Methoxyphenyl)ethanol
A impurity of Rivastigmine.Rivastigmine is a cholinesterase inhibitor. It works by increasing the amount of a certain substance (acetylcholine) in the brain, which may help reduce symptoms of dementia in patients with Alzheimer disease. Synonyms: 1-(3-methoxyphenyl)ethanol; 1-(3-methoxyphenyl)ethanol. Grades: 99 %. CAS No. 23308-82-9. Molecular formula: C9H12O2. Mole weight: 152.19.
14,15-Dehydro Triamcinolone Acetonide
Cas No. 1260149-96-9.
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol; 4-[4-(4-aminophenyl)-1-piperazinyl]phenol. Grades: >95%. CAS No. 74853-08-0. Molecular formula: C16H19N3O. Mole weight: 269.34.
1-(4-Chloro-3-(trifluoromethyl)phenyl)urea
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]urea; Sorafenib Impurity 1; Sorafenib related compound 1; 1-[3-(Trifluoromethyl)-4-chlorophenyl]urea; Sorafenib Related Compound 9. Grades: > 95%. CAS No. 343247-69-8. Molecular formula: C8H6ClF3N2O. Mole weight: 238.59.
1-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide D-Gluconic Acid Salt
15-cis-Phytoene
15-cis-Phytoene is an intermediate in the biosynthesis of carotenoids. Synonyms: y,y-Carotene,7,7,8,8,11,11,12,12-octahydro-, 15-cis-. Grades: > 95%. CAS No. 13920-14-4. Molecular formula: C40H64. Mole weight: 544.96.
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester. CAS No. 1420791-14-5. Molecular formula: C26H35F3O6. Mole weight: 500.56.
15-epi-Travoprost Epoxide
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Molecular formula: C26H35F3O7. Mole weight: 516.56.