BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CMP-9-fluoresceinyl-NeuAc | CMP-9-fluoresceinyl-NeuAc, is shown to be a suitable donor substrate for sialyltransferase, which belongs to glycosyltransferase family 29. Synonyms: N-Acetyl-9-deoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-2-(hydrogen 5'-cytidylate) β-Neuraminic Acid; 5-(Acetylamino)-3,5,9-trideoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-D-glycero-β-D-galacto-2-Nonulopyranosonic Acid 2-(Hydrogen 5'-cytidylate); Spiro[isobenzofuran-1(3H),9'-[9H]xanthene] D-glycero-β-D-galacto-2-nonulopyranosonic acid Deriv. CAS No. 118720-35-7. Molecular formula: C41H43N6O20PS. Mole weight: 1002.85. |  |
| CMP-9-O-acetyl-N-acetylneuraminic acid | CMP-9-O-acetyl-N-acetylneuraminic acid is an indispensable compound, having multifarious utilities in an array of maladies, ranging from influenza to viral infections and autoimmune disorders. The distinctive attributes it possesses render it an imperative constituent for investigating sialic acid metabolism and glycoconjugate. Synonyms: CMP-9-O-Ac-Neu5Ac. Molecular formula: C22H33N4O16P. Mole weight: 640.49. | |
| CMP-C9-Azido-Sialic Acid sodium | CMP-C9-Azido-Sialic Acid is a synthetic derivative belonging to the sialic acid family found in many types of glycoproteins and glycolipids. Grade: ≥85%. Molecular formula: C20H31N7NaO15P. Mole weight: 663.47. | |
| CMP-CP | CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Cytidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 101536-15-6. Molecular formula: C10H17N3O10P2 (free acid). Mole weight: 401.2 (free acid). | |
| CMPD-1 | CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4. | |
| CMPD101 | CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors. Synonyms: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide. Grade: 98%. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.46. | |
| CMPDA | CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. Synonyms: CMPDA; 380607-77-2; N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide; A36XX25K37; N-[2-[4-[2-(propan-2-ylsulfonylamino)ethyl]phenyl]ethyl]propane-2-sulfonamide; N,N'-(Benzene-1,4-Diyldiethane-2,1-Diyl)dipropane-2-Sulfonamide; 2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis-; UNII-A36XX25K37; SCHEMBL6565144; BCP23929; AKOS024458123; CS-3632; HY-12508; MS-26117; E99011; Q27465085; N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonamide; RNN. Grade: >98%. CAS No. 380607-77-2. Molecular formula: C16H28N2O4S2. Mole weight: 376.53. | |
| CMP - lyophilized | CMP - lyophilized is an extensively employed biomolecule in the field of biomedical sciences due to its pivotal involvement in the intricate processes of DNA research and development and repair. Through serving as a fundamental constituent for nucleic acids, CMP assuming a critical role in facilitating cellular functions. Synonyms: Cytidine-5'-monophosphate, Disodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N3O8P (free acid). Mole weight: 323.20 (free acid). | |
| CMP-N-acetylneuraminic acid sodium salt | CMP-N-acetylneuraminic acid sodium salt, a fundamental compound employed in the field of biomedicine, exhibits immense utility in the management of diverse ailments associated with compromised sialic acid metabolism, including sialuria and sialic acid storage diseases. Synonyms: CMP-NANA; Cytidine 5-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid; CMP-Neu5Ac. CAS No. 3063-71-6. Molecular formula: C20H30N4NaO16P. Mole weight: 636.43. | |
| CMP-Neu5,9Ac2 | CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Synonyms: β-Neuraminic acid, N-acetyl-, 9-acetate 2-(hydrogen 5'-cytidylate), ammonium salt (1:2). CAS No. 1045785-97-4. Molecular formula: C22H33N4O17P.2NH3. Mole weight: 690.55. | |
| CMP-Neu5Ac sodium salt | CMP-Neu5Ac sodium salt, a vital compound in the biomedical sector, is intricately involved in numerous biological processes, aiding in the synthesis of sialylated compounds. Notably, its indispensable role as a substrate for sialyltransferases facilitates the treatment of ailment manifestations characterized by aberrant sialylation. Afflicting individuals are plagued by a range of conditions, including cancer, neurological disorders, and autoimmune diseases, wherein CMP-Neu5Ac sodium salt assumes significance. Synonyms: CMP-NANA; Cytidine 5'-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid. Grade: 85%. CAS No. 1007117-62-5. Molecular formula: C20H30N4O16P·Na. Mole weight: 636.43. | |
| CMP-Neu5Az sodium | CMP-Neu5Az is a modified sialic acid nucleotide commonly used in glycosylation research, particularly for bioorthogonal labeling and metabolic engineering of sialic acids. Grade: ≥85%. Molecular formula: C20H28N7Na2O16P. Mole weight: 699.43. | |
| CMP-N-glycolylneuraminic acid | CMP-N-glycolylneuraminic acid is a fundamental compound extensively used in the biomedical field, serving as an indispensable precursor in the research and development of diverse sialic acid derivatives, which wield significant influence over a plethora of intricate biological mechanisms. Synonyms: N-(2-hydroxyacetyl)-b-neuraminic acid 2-(hydrogen 5-cytidylate); CMP-NeuGc. CAS No. 98300-80-2. Molecular formula: C20H31N4O17P. Mole weight: 630.45. | |
| CMP-Pseudaminic acid | CMP-Pseudaminic acid is a compound of immense value, serving as a fundamental building block for the bioresearch and development of pseudaminic acid, a vital constituent of bacterial glycosylated proteins. By impeding enzymatic development, CMP-Pseudaminic acid reveals promising prospects for research of bacterial infections triggered by notorious pathogens like Campylobacter jejuni and Helicobacter pylori. Synonyms: CMP-Pse. Molecular formula: C22H34N5O15P. Mole weight: 639.5. | |
| CMX 001 | CMX 001 is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells.An alkoxyalkyl ester prodrug containing the synthetic, acyclic nucleoside monophosphate analog cidofovir linked, through its phosphonate group, to a lipid, 3-hexadecyloxy-1-propanol, with antiviral activity against double-stranded DNA viruses. Uses: Broad spectrum antiviral drug. Synonyms: CMX 001; CMX-001; CMX001; HDP-CDV; HDPCDV; Brincidofovir; [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethyl-(3-hexadecoxypropoxy)phosphinic acid. Grade: ≥98%. CAS No. 444805-28-1. Molecular formula: C27H52N3O7P. Mole weight: 561.70. | |
| c-Myc inhibitor 4 | c-Myc inhibitor 4 is a potent and orally bioavailable c-MYC-reducing compound. Synonyms: 2-[6-[(2S,5S)-2,5-dimethylpyrrolidin-1-yl]pyridin-3-yl]-4-fluoro-7-methoxy-N-methyl-1-[[(2S)-morpholin-2-yl]methyl]benzimidazole-5-carboxamide. Molecular formula: C26H33FN6O3. Mole weight: 496.58. | |
| CNQX | CNQX, also known as FG9065, is a potent and competitive AMPA/kainate receptor antagonist and also an antagonist at glycine modulatory site on NMDA receptor complex. Uses: Excitatory amino acid antagonists. Synonyms: FG 9065; FG-9065; FG9065; 6-Cyano-2,3-dihydroxy-7-nitroquinoxaline; 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile. Grade: 98%. CAS No. 115066-14-3. Molecular formula: C9H4N4O4. Mole weight: 232.15. | |
| CNQX disodium salt | The sodium salt form of CNQX, which is an AMPA/kainate antagonist and could be used in studies of neurological disorders or damage. Synonyms: 6-Cyano-7-nitroquinoxaline-2,3-dione disodium. Grade: ≥99% by HPLC. CAS No. 479347-85-8. Molecular formula: C9H2N4O4Na2. Mole weight: 276.12. | |
| CNS-5161 | CNS-5161, a novel NMDA ion-channel antagonist, interacts with NMDA receptor/ion channel sites to produce a non-competitive blocking effect on glutamate. Synonyms: 3-(2-Chloro-5-(methylthio)phenyl)-1-methyl-1-(3-(methylthio)phenyl)guanidine; Guanidine, N'-(2-chloro-5-(methylthio)phenyl)-N-methyl-N-(3-(methylthio)phenyl)-; N''-(2-Chloro-5-methylsulfanyl-phenyl)-N-methyl-N-(3-methylsulfanyl-phenyl)-guanidine. Grade: 95%. CAS No. 160754-76-7. Molecular formula: C16H18ClN3S2. Mole weight: 351.92. | |
| CNS-5161 hydrochloride | CNS-5161 hydrochloride, a novel NMDA ion-channel antagonist, interacts with NMDA receptor/ion channel sites to produce a non-competitive blocking effect on glutamate. Synonyms: CNS 5161A; Guanidine, N''-[2-chloro-5-(methylthio)phenyl]-N-methyl-N-[3-(methylthio)phenyl]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 160756-38-7. Molecular formula: C16H19Cl2N3S2. Mole weight: 388.38. | |
| CNV-2197944 | CNV-2197944, a selective, state-dependent Cav2.2 calcium channel blocker, can reverse hyperalgesia associated with injury or inflammation in conjunction with the opioid. (Extracted from patent WO2017046581A1, compound 1). Synonyms: Cav 2.2 blocker 2; CNV2197944; Methanone, (2-methyl-3-pyridinyl)((2S)-2-methyl-4-((4-(trifluoromethyl)phenyl)sulfonyl)-1-piperazinyl)-; (S)-(2-Methyl-4-((4-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(2-methylpyridin-3-yl)methanone. Grade: ≥98%. CAS No. 1204535-44-3. Molecular formula: C19H20F3N3O3S. Mole weight: 427.44. | |
| CNX-1351 | CNX-1351 is a selective covalent Inhibitor of PI3Kα. In an end point assay, CNX-1351 potently inhibited PI3Kα and was 20-400 times less potent against β, γ, and δ. CNX-1351 inhibit PI3Kα signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX-1351 inhibits growth of cells dependent on PI3Kα. CNX-1351 also inhibits PI3Kα signaling in vivo and bonds to p110α. Synonyms: CNX-1351; CNX 1351; CNX1351. Grade: 0.98. CAS No. 1276105-89-5. Molecular formula: C30H35N7O3S. Mole weight: 573.716. | |
| CNX-2006 | CNX-2006 is a potent and mutant-selective EGFR inhibitor with excellent in vitro activity in cells with activating EGFR mutations, as well as in cells harbouring the T790M mutation. CNX-2006 is the prototype for CO-1686, which is currently in a Phase I clinical trial for the treatment of EGFR-mutant lung cancer. Synonyms: CNX2006; CNX 2006; N-[3-[[2-[4-[[1-(2-fluoroethyl)azetidin-3-yl]amino]-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide. Grade: 98%. CAS No. 1375465-09-0. Molecular formula: C26H27F4N7O2. Mole weight: 545.543. | |
| CNX-500 | CNX-500, a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin, still has inhibitory activity against Btk (IC50 = 0.5 nM) and forms a covalent bond with Btk. CNX-500 has a low inhibitory effect on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn. Synonyms: N1-[19-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-4,7,10-trioxa-14-azanonadec-1-yl]-N5-[3-[3-[[5-methyl-4-[[3-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-2-pyrimidinyl]amino]phenoxy]propyl]pentanediamide; N-(3-{3-[(4-{[3-(Acryloylamino)phenyl]amino}-5-methyl-2-pyrimidinyl)amino]phenoxy}propyl)-N'-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}pentanediamide. Grade: ≥98%. CAS No. 1202758-21-1. Molecular formula: C48H68N10O9S. Mole weight: 961.18. | |
| CNX-774 | CNX-774 is a potent Btk inhibitor (IC50 < 1 nM). Synonyms: CNX-774; CNX 774; CNX774. CAS No. 1202759-32-7. Molecular formula: C26H22FN7O3. Mole weight: 499.49638. | |
| Co 101244 | Co 101244 is an N-methyl-D-aspartate NR2B subtype antagonist. Synonyms: 1-[2-(4-Hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol; PD 174494; Ro 63-1908; Co 101244; PD 174494; Ro63-1908; Co101244; PD174494; Ro-63-1908; Co-101244. CAS No. 193359-26-1. Molecular formula: C21H27NO3. Mole weight: 341.45. | |
| Co 101244 hydrochloride | Co 101244 hydrochloride, with strongly neuroprotective effect in vivo and in vitro, is an ifenprodil-like noncompetitive, highly selective antagonist of NR2B-containing NMDA receptors (IC5= 43 nM). Synonyms: 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol; hydrochloride; 4-hydroxy-N-(2-(4-hydroxyphenoxy)ethyl)-4-(4-methylbenzyl)piperidine; Co 101244; 193359-26-1 (Co 101244 free base); Co-101244; Co101244; PD 174494; PD-174494; PD174494. Grade: >98%. CAS No. 193356-17-1. Molecular formula: C21H27NO3.HCl. Mole weight: 377.91. | |
| Co 102862 | Co 102862, also known as V102862, an orally active anticonvulsant with robust activity, is a potent, broad-spectrum state-dependent inhibitor of mammalian voltage-gated Na+ channels with ~ 80-fold higher affinity for inactivated Na+ channels compared to channels in the resting state. Synonyms: CO-102862; CO 102862; CO102862; [[4-(4-fluorophenoxy)phenyl]methylideneamino]urea; 4-(4-fluorophenoxy)benzaldehyde semicarbazone; Co 102862; Co-102862; FPhOBal semicarbazone; 181144-66-1; 2-(4-(4-Fluorophenoxy)benzylidene)hydrazinecarboxamide; Hydrazinecarboxamide, 2-[[4-(4-fluorophenoxy)phenyl]methylene]-. Grade: >99 %. CAS No. 181144-66-1. Molecular formula: C14H12FN3O2. Mole weight: 273.26. | |
| CO-1686 hydrobromide | CO-1686 hydrobromide is the hydrobromide salt form of CO-1686. CO-1686, also called as Rociletinib, is an oral tyrosine kinase inhibitor that irreversibly and selectively inhibits mutation of EGFR for treating Non-small cell lung cancer.Non-small cell lun. Synonyms: N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide; hydrobromide CO-1686 (hydrobromide) CO-1686 hydrobromide HY-15729A CS-5247 KB-310894 1446700-26-0. CAS No. 1446700-26-0. Molecular formula: C27H29BrF3N7O3. Mole weight: 636.46. | |
| CO23 | CO23, a selective thyroid hormone receptor α (TRα) agonist, regulates growth and development and can be transported across the blood-brain barrier. Synonyms: 2,4-Imidazolidinedione, 5-[[4-[4-hydroxy-3-(1-methylethyl)phenoxy]-3,5-diiodophenyl]methyl]-; 5-(3,5-Diiodo-4-(3-isopropyl-4-hydroxyphenoxy)benzyl)imidazolidine-2,4-dione; 5-[4-(4-Hydroxy-3-isopropylphenoxy)-3,5-diiodobenzyl]-2,4-imidazolidinedione; 5-{4-[4-hydroxy-3-(propan-2-yl)phenoxy]-3,5-diiodobenzyl}imidazolidine-2,4-dione. Grade: ≥95%. CAS No. 1370363-74-8. Molecular formula: C19H18I2N2O4. Mole weight: 592.17. | |
| CoA-S-acetyl-tryptamine | CoA-S-acetyl-tryptamine is a biomedical product exerting vital influence over specialized receptors implicated in neurotransmission. Molecular formula: C33H48N9O17P3S. Mole weight: 967.77. | |
| Cobalamin | One of the analog of Vitamin B12, which has been found to be related to the metabolism of cells in human body, especially DNA synthesis, amino acid as well as fatty acid metabolism. Synonyms: Cobinamide, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), ion(1+); Cobinamide, hydroxide, ion(1+), dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole; Cobinamide, hydroxide, ion(1+), dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole; Cobinamide, ion(1+), dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole; Cobalamine. Grade: 95%. CAS No. 13408-78-1. Molecular formula: C62H88CoN13O14P. Mole weight: 1329.35. | |
| Cobamamide | Cobamamide is a biologically active form of vitamin B12. It is a cofactor for various enzymes. Synonyms: Adenosine Cobalamin; Cobinamide, Co-(5'-deoxyadenosin-5'-yl)-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3); Cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-Dribofuranosyl-1H-benzimidazole; Cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrog. Grade: ≥95%. CAS No. 13870-90-1. Molecular formula: C72H100CoN18O17P. Mole weight: 1579.58. | |
| Cobicistat | Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate. Uses: Anti-hiv agents. Synonyms: Cobicistat, GS-9350; GS 9350; GS9350. Grade: 98%. CAS No. 1004316-88-4. Molecular formula: C40H53N7O5S2. Mole weight: 776.028. | |
| Cobicistat Impurity ((2S)-2-Amino-4-Meorpholine-4-yl-Butanoic Acid) | Cobicistat Impurity serves as an impurity for the drug Cobicistat, which is frequently prescribed to treat human immunodeficiency virus (HIV) infection. Synonyms: 2-Amino-4-morpholinobutanoic acid; 2-amino-4-(morpholin-4-yl)butanoic acid; 770684-35-0; 2-amino-4-morpholin-4-ylbutanoic acid; (2S)-2-Amino-4-morpholinebutanoicAcidDihydrochloride; 854893-19-9; SCHEMBL1889261; 2-Amino-4-morpholinobutanoicacid; MFCD07786927; AKOS000212411; BS-9757; 2-Amino-4-(mopholin-4-yl) butanoic acid; EN300-91881. Grade: > 95%. CAS No. 854893-19-9. Molecular formula: C8H16N2O3. Mole weight: 188.23. | |
| Cobicistat Impurity HCl | α,α-Dimethyl-4-[(methylamino)methyl]-2-thiazolemethanol Hydrochloride is a Cobicistat impurity. Cobicistat is a HIV protease inhibitor and have been coadministered with low-dose ritonavir as a pharmacoenhancer, significantly increasing their plasma concentrations. Synonyms: α,α-Dimethyl-4-[(methylamino)methyl]-2-thiazolemethanol Hydrochloride. Grade: > 95%. Molecular formula: C8H15ClN2OS. Mole weight: 222.74. | |
| Cobimetinib | Cobimetinib (GDC-0973, RG7420) is a potent, orally available and highly selective MEK1 inhibitor with IC50 of 4.2 nM. It shows more than 100-fold selectively for MEK1 over MEK2 when tested against a panel of more than 100 serine-threonine and tyrosine kinases and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Synonyms: XL518; GDC-0973; RG7420. Grade: ≥98%. CAS No. 934660-93-2. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
| Cobimetinib hemifumarate | Cobimetinib, also known as GDC-0973 and XL-518, is a novel selective MEK inhibitor, and the IC50value against MEK1 is 4.2 nM, with potential antineoplastic activity. Synonyms: Methanone, [3,?4-difluoro-2-[(2-fluoro-4-iodophenyl)?amino]?phenyl]?[3-hydroxy-3-(2S)?-2-piperidinyl-1-azetidinyl]?-, (2E)?-2-butenedioate (2:1). CAS No. 1369665-02-0. Molecular formula: C21H21F3IN3O2.1/2C4H4O4. Mole weight: 589.35. | |
| Cobimetinib racemate | Cobimetinib racemate is a selective inhibitor of MEK. It is also known as mitogen activated protein kinase kinase (MAPKK) and is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Synonyms: GDC-0973 racemate; XL-518; GDC 0973 racemate; XL 518; GDC0973 racemate; XL518. Grade: >98%. CAS No. 934662-91-6. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
| Cobimetinib (R-enantiomer) | Cobimetinib (R-enantiomer) is a selective inhibitor of MEK. It is also known as mitogen activated protein kinase kinase (MAPKK) and is a key component of the RAS/RAF/MEK/ERK pathway, which is frequently activated in human tumors. Synonyms: GDC-0973 R-enantiomer; XL-518 R-enantiomer; GDC0973 R-enantiomer; XL518 R-enantiomer; GDC 0973 R-enantiomer; XL 518 R-enantiomer. Grade: >98%. CAS No. 934660-94-3. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. | |
| Cobolimab | Cobolimab is a monoclonal antibody directed against the inhibitory T-cell receptor, T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), with potential immune checkpoint inhibitory and antineoplastic activities. Cobolimab has the potential for the treatment of non-small cell lung cancer (NSCLC). Synonyms: TSR-022; TSR 022; TSR022; GSK-4069889; GSK 4069889; GSK4069889. Grade: 95%. CAS No. 2022215-65-0. | |
| Cocamidopropyl Betaine | Cocamidopropyl betaine is an organic compound derived from coconut oil and dimethylaminopropylamine. It is used as a surfactant in personal care products. Uses: Cosmetic raw materials. Synonyms: 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts; NorfoxCapb; 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., inner salts; N-Cocamidopropyl-N,N-dimethylglycine inner salt. Grade: Active Content: 30±2%. CAS No. 61789-40-0. | |
| Cocarboxylase Tetrahydrate | Cocarboxylase Tetrahydrate is a bioactive compound, operating as a proficient biomedical remedy for diverse metabolic intricacies, predominantly encompassing thiamine insufficiency. Operating in tandem with metabolic courses within the organism, this remarkable coenzyme actively facilitates the vital conversion of carbohydrates into substantial energy units. Synonyms: Thiamine diphosphoric acid ester. Grade: > 95%. CAS No. 68684-55-9. Molecular formula: C12H18N4O7P2S 4H2O. Mole weight: 496.37. | |
| Cochineal | Cochineal is a natural red dye derived from insects commonly used in the biomedical industry for its unique properties. It is utilized in various medications and studies involving cell imaging, histology, and immunology. Uses: Food coloring agents. Synonyms: Carmine. CAS No. 1343-78-8. Molecular formula: C22H20O13. Mole weight: 492.39. | |
| Cochlioquinone D | Cochlioquinone D is a flavonoid that acts as an antibacterial and antioxidant, and it increases the resistance of rice to the white-backed planthopper (WBPH). CAS No. 173355-88-9. Molecular formula: C28H38O6. Mole weight: 470.60. | |
| Coclaurine Related Compound 1 | (S)-3'-Hydroxy-N-methylcoclaurine is an structure analog of Coclaurine, a benzyltetrahydroisoquinoline alkaloid extracted from Magnolia salicifolia. Synonyms: (S)-3'-Hydroxy-N-methylcoclaurine Hydrochloride; (S)-4-[(1,2,3,4-Tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl)methyl]-1,2-benzenediol Hydrochloride. Grade: > 95%. CAS No. 138644-99-2. Molecular formula: C18H22ClNO4. Mole weight: 351.8. | |
| Coco Alkyldimethyl Betaine | Coco Alkyldimethyl Betaine is a remarkable compound prevailing in the pharmaceutical sector exhibiting its notable presence as a prime constituent in personal care commodities, specifically shampoos and body washes. By virtue of its innate prowess, it imparts unparalleled conditioning and moisturizing attributes. Synonyms: Betaines, coco alkyldimethyl; Alkyl(C8-C18) aminobetaine; Betaine, Kokos-alkyldimethyl-; N-(Cocoalkyl)-N,N-dimethylbetaine; N-coco-N-dimethylcarboxymethylene betaines. CAS No. 68424-94-2. | |
| Codergocrine mesilate | Codergocrine mesilate is a mixture of the methanesulfonate salts of three dihydrogenated ergot alkaloids. It binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site. It also interacts with central dopaminergic, serotonergic and adrenergic (α1) receptors. It displays antiproliferative activity and cognition-enhancing, anticonvulsant and sedative activity in vivo. It has been used to treat dementia and age-related cognitive impairment, such as in Alzheimer disease, as well as to aid in recovery after stroke. It may be used in conjunction with other cerebral enhancers like piracetam, with which it may act synergistically. It was developed by Albert Hofmann for Sandoz (now part of Novartis). Uses: Codergocrine mesilate displays antiproliferative activity and cognition-enhancing, anticonvulsant and sedative activity in vivo. it has been used to treat dementia and age-related cognitive impairment, such as in alzheimer disease, as well as to aid in recovery after stroke. it may be used in conjunction with other cerebral enhancers like piracetam, with which it may act synergistically. Synonyms: CCK 179, CCK-179, CCK179; Dihydroergotoxine mesylate; Dihydroergotoxine methanesulfonate; Dihydroergotoxine methanesulphonate; Dihydroergotoxine monomethanesulfonate(salt); Ergoloid mesylates. Grade: 95%. CAS No. 8067-24-1. Molecular formula: C20H29N3O5S. Mole | |
| Codrituzumab | Codrituzumab is a humanized monoclonal antibody against Glypican-3 (GPC3). Codrituzumab binds to GPC3 and suppresses GPC3-expressing tumor cell growth. Synonyms: GC33; RO5137382. CAS No. 1365267-33-9. | |
| Coenzyme A, S-(2E)-2-butenoate, tetralithium salt | Coenzyme A, S-(2E)-2-butenoate, tetralithium salt. Synonyms: Coenzyme A, S-2-butenoate, tetralithium salt, (E)-. CAS No. 102680-35-3. Molecular formula: C25H36N7O17P3S.4Li. Mole weight: 859.34. | |
| Coenzyme A S-(2-Ethyl-3-oxobutanoate) | Coenzyme A S-(2-Ethyl-3-oxobutanoate) is an derivative of Coenzyme A, a cofactor in enzymatic acetyl transfer reactions. Molecular formula: C27H44N7O18P3S. Mole weight: 879.6. | |
| Coenzyme A S-Pyrazinecarboxylate-d3 | Coenzyme A S-Pyrazinecarboxylate-d3 is the isotope labelled analog of Coenzyme A S-Pyrazinecarboxylate, which is a derivative of Coenzyme A. Molecular formula: C26H35D3N9O17P3S. Mole weight: 876.63. | |
| Coenzyme A S-Pyrazinecarboxylate Trisodium Salt | Coenzyme A S-Pyrazinecarboxylate is a derivative of Coenzyme A; a cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase. Synonyms: S-(2-(3-((2R)-4-(((((((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)-2-hydroxy-3,3-dimethylbutanamido)propanamido)ethyl) Pyrazine-2-carbothioate Trisodium Salt. Molecular formula: C26H35N9Na3O17P3S. Mole weight: 939.56. | |
| Coenzyme A Trilithium Salt | A cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase. Synonyms: CoA Trilithium Salt; Trilithium Coenzyme A. Grade: 95%. CAS No. 18439-24-2. Molecular formula: C21H33Li3N7O16P3S. Mole weight: 785.33. | |
| COH000 | COH000 is an allosteric and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme). COH000 targets a cryptic pocket distinct from the active site that is completely buried in all previous SUMO E1 structures. Synonyms: (1R,4S)-Dimethyl 1-((R)-1-(phenylamino)-2-(p-tolyl)ethyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate. CAS No. 1534358-79-6. Molecular formula: C25H25NO5. Mole weight: 419.47. | |
| COH-29 | COH-29 is a potent inhibitor of ribonucleotide reductase (RNR). It inhibits recombinant RNR small subunit (RRM1/RRM2) activity in vitro with IC50 of 16 μM. Synonyms: RNR Inhibitor COH29. CAS No. 1190932-38-7. Molecular formula: C22H16N2O5S. Mole weight: 420.44. | |
| COH34 | COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor that binds to the catalytic domain of PARG, thereby prolonging PARylation at DNA lesions and trapping DNA repair factors. Synonyms: COH-34; COH 34. Grade: >98%. CAS No. 906439-72-3. Molecular formula: C18H15NOS. Mole weight: 293.38. | |
| Cohumulone | Cohumulone is one of three major analogues of hop a-acids, the others being adhumulone and humulone. Synonyms: Cohumulone; 511-25-1; 142628-20-4; 2Y34G4NIC8; (+/-)-cohumulone; 3,5,6-trihydroxy-4,6-bis(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one; 5-(alpha,beta-Dibromophenethyl)-5-methylhydantoin; UNII-2Y34G4NIC8; 2,5-Cyclohexadien-1-one, 3,4,5-trihydroxy-2-isobutyryl-4,6-bis(3-methyl-2-butenyl)-; COHUMULONE, (-)-; SCHEMBL317724; SCHEMBL13629034; GTPL12422; DTXSID20931549; CHEBI:175443; DRSITEVYZGOOQG-UHFFFAOYSA-N; DTXSID701318500; Q2981886; Q27893896; (-)-3,4,5-TRIHYDROXY-2,4-BIS(3-METHYL-2-BUTEN-1-YL)-6-(2-METHYL-1-OXOPROPYL)-2,5-CYCLOHEXADIEN-1-ONE; 2,5-CYCLOHEXADIEN-1-ONE, 3,4,5-TRIHYDROXY-2,4-BIS(3-METHYL-2-BUTEN-1-YL)-6-(2-METHYL-1-OXOPROPYL)-, (-)-; 3,4,5-Trihydroxy-2,4-bis(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-2,5-cyclohexadien-1-one, 9CI; 3,5,6-TRIHYDROXY-4,6-BIS(3-METHYLBUT-2-EN-1-YL)-2-(2-METHYLPROPANOYL)CYCLOHEXA-2,4-DIEN-1-ONE. Grade: > 95%. CAS No. 511-25-1. Molecular formula: C20H28O5. Mole weight: 348.44. | |
| Col003 | Col003 is a potent and selective collagen-heat-shock protein 47 (Hsp47) interaction inhibitor with IC50 of 1.8 μM. Synonyms: 5-benzyl-2-hydroxy-3-nitro-benzaldehyde. Grade: 99%. CAS No. 328565-16-8. Molecular formula: C14H11NO4. Mole weight: 257.24. | |
| Colchicine EP Impurity A | Colchicine EP Impurity A is a Colchicine derivative. It is a new alkaloid from Gloriosa superba. Synonyms: N-Deacetyl-N-formyl Colchicine; Gloriosine; N-Formyldeacetylcolchicine; N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]formamide. Grade: > 95%. CAS No. 7411-12-3. Molecular formula: C21H23NO6. Mole weight: 385.41. | |
| Colchicine EP Impurity B | Colchicine EP Impurity B is a Colchicine derivative. It is a new alkaloid from Gloriosa superba. Synonyms: Colchicine Conformational Isomer; N-[(7S,12aP)-1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide; (-)-N-[(7S,12aSa)-1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| Colchicine EP Impurity D | Colchicoside is a significantly toxic Colchicine analog with no anti-inflammatory properties. Synonyms: (S)-N-[3-(b-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; N-[(7S)-3-(b-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; 3-Demethylcolchicine glucoside. Grade: > 95%. CAS No. 477-29-2. Molecular formula: C27H33NO11. Mole weight: 547.55. | |
| Colchicine EP Impurity E | 3-Demethyl Colchicine is a metabolite of Colchicine. Synonyms: 3-Demethyl Colchicine; O3-Demethylcolchicine; 3-Demethyl-(-)-colchicine; 3-Demethylcolchicine; N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-acetamide. Grade: > 95%. CAS No. 7336-33-6. Molecular formula: C21H23NO6. Mole weight: 385.41. | |
| Colchicine EP Impurity F | Colchicine EP Impurity F is a Colchicine derivative. It is a new alkaloid from Gloriosa superba. Uses: A metabolite of colchicine. Synonyms: Colchiceine; 10-O-Demethylcolchicine; O10-Demethylcolchicine; N-Acetyl trimethylcolchicinic acid; N-[(7S,12aM)-10-Hydroxy-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide. Grade: 95%. CAS No. 477-27-0. Molecular formula: C21H23NO6. Mole weight: 385.41. | |
| Colesevelam Aminoquat Impurity HBr | (6-Aminohexyl)trimethylammonium Bromide is a potent inhibitor and acts as substrate for pig kidney diamine oxidase. Synonyms: (6-Aminohexyl)trimethylammonium Bromide Hydrobromide. Grade: > 95%. CAS No. 33968-67-1. Molecular formula: C9H24N2Br2. Mole weight: 320.11. | |
| Colesevelam Hydroxyquat Impurity | Colesevelam Hydroxyquat Impurity is an impurity of colesevelam hydroxyquat, a pharmaceutical agent efficacious in treating hyperlipidemia and type 2 diabetes. Grade: > 95%. CAS No. 676578-21-5. Molecular formula: C9H22NOCl. Mole weight: 195.73. | |
| Colesevelam Methoxyquat Impurity | Colesevelam Methoxyquat Impurity is an impurity of Colesevelam, paramount pharmaceutical drug serving to ameliorate cholesterol levels and optimize glycemic regulation amidst individuals afflicted by type 2 diabetes mellitus. Grade: > 95%. CAS No. 863031-14-5. Molecular formula: C10H24NOI. Mole weight: 301.21. | |
| Colibactin 742 | Colibactin 742 is a stable colibactin derivative that induces DNA interstrand-cross-links, activates the Fanconi anemia DNA repair pathway and leads to G2/M arrest. Synonyms: N-((4-(2-(4-(3-hydroxy-4-(6-((S)-2-methyl-3,4-dihydro-2H-pyrrol-5-yl)-5-oxo-4-azaspiro[2.4]hept-6-en-7-yl)-5-oxopyrrolidin-3-yl)thiazol-2-yl)ethyl)thiazol-2-yl)methyl)-2-(6-((S)-2-methyl-3,4-dihydro-2H-pyrrol-5-yl)-5-oxo-4-azaspiro[2.4]hept-6-en-7-yl)acetamide. Molecular formula: C37H42N8O5S2. Mole weight: 742.91. | |
| Colistimethate sodium | Colistimethate sodium is a polymyxin B antibiotic that inhibits bacterial growth by binding to the cell membrane. It is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options. Synonyms: Colistin-1,3,5,9-tetramethanesulfonic A acid. CAS No. 30387-39-4. Molecular formula: C57H108N16O25S4. Mole weight: 1545.82. | |
| Colistin adjuvant-1 | Colistin adjuvant-1 shows increased colistin potentiation activity against Gram-negative bacteria. It inhibits NF-κB with an IC50 of 0.209 μM. Molecular formula: C16H7F9N2O. Mole weight: 414.22. | |
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