BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cotinine | Cotinine is the major metabolite of nicotine. It is an alkaloid commonly found in Nicotiana tabacum. It has a role as a biomarker, an antidepressant, a plant metabolite, and a human xenobiotic metabolite. Uses: A carcinogen as a a major metabolite of nicotine in humans. Synonyms: Nicotine Impurity C; Nicotine EP Impurity C; (5S)-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one; 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)-; S-(-)-Cotinine; NIH 10498; NIH10498; NIH-10498; (-)-Cotinine; (5S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone; (S)-(-)-1-Methyl-5-(3-pyridiyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-; (S)-Cotinine. Grade: ≥95%. CAS No. 486-56-6. Molecular formula: C10H12N2O. Mole weight: 176.22. |  |
| Cotinine-d7 | Cotinine-d7 is a labelled major metabolite of nicotine in humans. Grade: > 95%. Molecular formula: C10H5N2OD7. Mole weight: 183.28. | |
| Cotinine N-(4-deoxy-4,5-didehydro)-b-D-glucuronide | Cotinine N-(4-deoxy-4,5-didehydro)-b-D-glucuronide, a remarkable biomedicine employed for investigating nicotine metabolism's impact on human health, embodies this rewritten product description. It serves as a valuable tool to unravel the intricate intricacies of nicotine pharmacokinetics and elimination, shedding light on its potential involvement in multifarious ailments like tobacco-related disorders and drug addiction. Synonyms: N-(b-D-4-Deoxy-4,5-didehydroglucopyranosyl)uronate, cotinium inner salt; Pyridinium, 1-(4-deoxy-α-L-threo-hex-4-enopyranuronosyl)-3-(1-methyl-5-oxo-2-pyrrolidinyl)-, inner salt, (S)-. CAS No. 146275-15-2. Molecular formula: C16H18N2O6. Mole weight: 334.32. | |
| Cotinine N-β-D-Glucuronide | Cotinine N-β-D-Glucuronide is a major metabolite of Nicotine in humans. Synonyms: 1-β-D-Glucopyranuronosyl-3-[(2S)-1-methyl-5-oxo-2-pyrrolidinyl]pyridinium Inner Salt; Cotinine-N-glucuronide. Grade: > 95%. CAS No. 139427-57-9. Molecular formula: C16H20N2O7. Mole weight: 352.34. | |
| Cotinine-N-D-glucoside Chloride | Glucoside of Cotinine. Carcinogen. Synonyms: 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone-β-D-glucoside Chloride. Molecular formula: C16H23ClN2O6. Mole weight: 374.82. | |
| Cotosudil | Cotosudil is a Rho-associated (ROCK) kinase inhibitor. It can be used for glaucoma or ocular hypertension research. Synonyms: (R)-6-((2-Methyl-1,4-diazocan-1-yl)sulfonyl)isoquinoline. Grade: 99%. CAS No. 1258833-31-6. Molecular formula: C16H21N3O2S. Mole weight: 319.42. | |
| COT Serinol Phosphoramidite | COT Serinol Phosphoramidite is an indispensable compound, facilitating the intricate research and development of bespoke nucleosides and nucleotides. Profoundly pivotal, this compound assumes a critical function in the development of tailored oligonucleotides, particularly pertaining to the research of hereditary afflictions and the establishment of targeted pharmaceutical transport mechanisms. Synonyms: 3-Dimethoxytrityloxy-2-(3-(3-cyclooctatetraenylpropanamido)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C47H59N4O7P. Mole weight: 822.97. | |
| Coumaran | Coumaran is a natural product found in Trigonella foenum-graecum, Xylaria, and other organisms with data available. Coumaran is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Synonyms: 2,3-Dihydrobenzofuran; Benzofuran, 2,3-dihydro-; Kumaran; Dihydrocoumarone. CAS No. 496-16-2. Molecular formula: C8H8O. Mole weight: 120.15. | |
| Coumaric acid 4-O-glucoside | Coumaric Acid 4-O-glucoside is a compound extensively utilized in the biomedical sector, exhibiting diverse pharmacological attributes encompassing anti-inflammatory and antioxidant activities. Notably it is employed in studying specific ailments such as diabetes and cardiovascular disorders. Grade: 98%. CAS No. 14364-05-7. Molecular formula: C15H18O8. Mole weight: 326.30. | |
| COX-2-IN-1 | A potent and slective COX-2 inhibitor(IC50= 3.9 μM). Synonyms: 1-(4-Sulfamylphenyl)-3-trifluoromethyl-5-(7-chloroindol-3-yl)-2-pyrazoline; 4-[3-(7-chloro-1H-indol-3-yl)-5-(trifluoromethyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide. CAS No. 787623-48-7. Molecular formula: C18H14ClF3N4O2S. Mole weight: 442.84. | |
| COX-2-IN-2 | COX2-IN-1 is a selective and inducible COX2 inhibitor (IC50= 0.24 μM) with anti-inflammatory and analgesic activities. Synonyms: 1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrazole-3-carbonitrile. CAS No. 134729-13-8. Molecular formula: C17H12FN3O2S. Mole weight: 341.36. | |
| COX-2-IN-6 | COX-2-IN-6, a gut-restricted selective COX-2 inhibitor, is used for chemoprevention of colorectal cancer. CAS No. 2756347-91-6. Molecular formula: C20H27NO6S. Mole weight: 409.50. | |
| COX-2 Inhibitor I | An inhibitor of COX-2. Synonyms: Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate; LM-1685; LM 1685; LM1685. CAS No. 416901-58-1. Molecular formula: C18H16ClNO4S. Mole weight: 377.8. | |
| COX-2 Inhibitor II | A selective inhibitor of COX-2. Synonyms: SC-791; IN1371; 181696-33-3; 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide; SCHEMBL214781. CAS No. 181696-33-3. Molecular formula: C16H12F2N2O3S. Mole weight: 350.34. | |
| COX/5-LO-IN-1 | A dual inhibitor of cylooxygenase and 5-lipoxygenase. Synonyms: Urea, N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-; 1-[4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea. CAS No. 154355-75-6. Molecular formula: C16H15FN2O2S. Mole weight: 318.37. | |
| CP-?060 | CP-060 is a novel type of Ca(2+) antagonist possessing both Ca(2+) overload inhibition, with antioxidant and cardioprotective activities. Synonyms: CP-060; CP060; CP 060; 3-[3-[2-(1,3-benzodioxol-5-yloxy)ethyl-methylamino]propyl]-2-(3,5-ditert-butyl-4-hydroxyphenyl)-1,3-thiazolidin-4-one. CAS No. 180090-15-7. Molecular formula: C30H42N2O5S. Mole weight: 542.73. | |
| CP 100356 | CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grade: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64. | |
| CP 100356 hydrochloride | The hydrochloride salt form of CP-100356, which has been found to be an inhibitor of MDR1 (P-Gp) and show inactive in inhibiting multidrug resistance-associated protein 2 (MPR2). Synonyms: CP 100356 hydrochloride; CP100356 hydrochloride; CP-100356 hydrochloride; 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride. Grade: ≥98% by HPLC. CAS No. 142715-48-8. Molecular formula: C31H36N4O6.HCl. Mole weight: 597.10. | |
| CP-100829 | CP-100829, an indole derivative, could probably be useful in some biological studies. Synonyms: CP-100829; CP100829; CP 100829; UNII-X7Y3B8B649. X7Y3B8B649; 1H-Indole-1-carboxamide, 6-chloro-3-((4-chloro-2-thienyl)carbonyl)-5-fluoro-2,3-dihydro-2-oxo-; 1H-Indole-1-carboxamide, 6-chloro-3-((4-chloro-2-thienyl)hydroxymethylene)-5-fluoro-2,3-dihydro-2-oxo-, (Z)-. Grade: 98%. CAS No. 172618-05-2. Molecular formula: C14H7Cl2FN2O3S. Mole weight: 373.18. | |
| CP 101606 | CP 101606 is a potent and selective NR2B antagonist of N-Methyl-D-Aspartate (NMDA) glutamate receptors. It decreases pentylenetetrazol-induced seizures. Synonyms: CP-101606; CP 101606; CP101606; Traxoprodil; 1-((1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol. Grade: 99%. CAS No. 134234-12-1. Molecular formula: C20H25NO3. Mole weight: 327.42. | |
| CP-105696 | CP-105696, a chromen derivative, has been found to be a leukotriene B4 receptor antagonist that was once studied against sorts of nflammatory disease. Uses: Leukotriene antagonists. Synonyms: CP-105696; UNII-Z7354TW4BM; CP-105,696; CHEMBL51770; CP 105696; Z7354TW4BM; 1-[(3S,4R)-4-hydroxy-3-[(4-phenylphenyl)methyl]-3,4-dihydro-2H-chromen-7-yl]cyclopentane-1-carboxylic acid. Grade: 98%. CAS No. 158081-99-3. Molecular formula: C28H28O4. Mole weight: 428.53. | |
| CP-114271 | CP-114271, a thiazole derivative, has been found to be a β3 adrenergic receptor agonist that was once studied in obesity therapy. Synonyms: CP-114271; CP 114271; CP114271; UL-TG 307; UL-TG-307; UNII-CY8W406YBX.; UL-TG 307; UL-TG-307; CY8W406YBX; Acetic acid, (4-((2R)-2-(((2S)-2-hydroxy-2-(2-(trifluoromethyl)-4-thiazolyl)ethyl)amino)propyl)phenoxy)-. Grade: 98%. CAS No. 162326-86-5. Molecular formula: C17H19F3N2O4S. Mole weight: 404.40. | |
| CP 115953 | CP 115953 is a Type II DNA topoisomerase inhibitor originated by Pfizer. CP 115953 inhibits topoisomerase II activity via an interaction with the enzyme and not by DNA unwinding. It can stimulate cytokine production by lymphocytes. Research for treatment of cancer was discontinued. Uses: Cancer. Synonyms: CP 115953; CP115953; CP-115953; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-3-quinolinecarboxylic acid. Grade: 98%. CAS No. 136440-70-5. Molecular formula: C19H13F2NO4. Mole weight: 357.31. | |
| CP 117227 | CP 117227, a dibenzocyclohepten derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in studies of anticancer. Synonyms: CP 117227; CP-117227; CP117227; 1-Piperazineethanol, 4-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)-alpha-((5-quinolinyloxy)methyl)-, (S)-. Grade: 98%. CAS No. 154531-78-9. Molecular formula: C31H33N3O2. Mole weight: 479.61. | |
| CP-122721 | CP-122721, a phenylpiperidin derivative, has been found to be a NK1 receptor antagonist that could probably be effective as antidepressant and antiemetic agent. The result of Phase II clinical trial for depression of it has not been reported yet since 2003. Synonyms: CP122721; CP 122721; 3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-piperidine. Grade: 98%. CAS No. 145742-28-5. Molecular formula: C20H23F3N2O2. Mole weight: 380.40. | |
| CP 135807 | CP 135807, an indole derivative, has been found to be a selective 5-HT1D receptor agonist. Synonyms: CP135807; CP-135807; 3-(N-Methylpyrrolidin-2-ylmethyl)-5-(3-nitropyrid-2-ylamino)-1H-indole; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine. Grade: ≥98% by HPLC. CAS No. 151272-90-1. Molecular formula: C19H21N5O2. Mole weight: 351.40. | |
| CP 141938 | CP 141938 is a potent and selective neurokinin-1 (NK1) receptor antagonist with very different brain tendencies and potency in centrally mediated activity models. Synonyms: Methanesulfonamide, N-[4-methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methyl-, rel-; Methanesulfonamide, N-[4-methoxy-3-[[(2-phenyl-3-piperidinyl)amino]methyl]phenyl]-N-methyl-, cis-; rel-N-[4-Methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide; CP141938; CP-141938. Grade: ≥95%. CAS No. 182822-62-4. Molecular formula: C21H29N3O3S. Mole weight: 403.54. | |
| CP 154526 | The hydrochloride salt form of CP-154526, which has been found to be a non-peptide CRF1 receptor antagonist and could exhibit anxiolytic-like activity at some extent. Synonyms: CP 154526; CP154526; CP-154526; N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 257639-98-8. Molecular formula: C23H32N4.HCl. Mole weight: 400.99. | |
| CP-195494 | CP-195494, a benzothiazol derivative, was once studied as a leukotriene receptor antagonist. Synonyms: UNII-1D055URF6U; CHEMBL300701; CP195494; CP 195494; CP-195494; (+)-CP-195494; 1D055URF6U; BDBM50070919. Grade: 98%. CAS No. 158103-57-2. Molecular formula: C26H22F4N2O5S2. Mole weight: 582.59. | |
| CP-195543 | CP-195543 is a potent and selective leukotriene B4 antagonist developed as an oral treatment for for inflammatory diseases. Synonyms: 2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-chromen-7-yl]-4-(trifluoromethyl)benzoic acid; 2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid; CP 195543; CP-195543; CP195543. Grade: >98%. CAS No. 204981-48-6. Molecular formula: C24H19F3O4. Mole weight: 428.4. | |
| CP-199330 | CP-199330, a chromen derivative, has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330; CP 199330; CP199330; UNII-V4WYK6T8QA; CHEMBL96206; V4WYK6T8QA; SCHEMBL8890632; BDBM50081532; N-[3-[[(3R,4R)-6-[(7-chloroquinolin-2-yl)methoxy]-4-hydroxy-3,4-dihydro-2H-chromen-3-yl]methyl]-4-methoxyphenyl]-1,1,1-trifluoromethanesulfonamide. Grade: 98%. CAS No. 158102-92-2. Molecular formula: C28H24ClF3N2O6S. Mole weight: 609.01. | |
| CP-199330 Sodium | The sodium salt form of CP-199330 which is a chromen derivative and has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330 sodium; CP 199330 sodium; CP199330 sodium; CP-199330 monosodium salt; Methanesulfonamide, N-(3-((6-((7-chloro-2-quinolinyl)methoxy)-3,4-dihydro-4-hydroxy-2H-1-benzopyran-3-yl)methyl)-4-methoxyphenyl)-1,1,1-trifluoro-, monosodium salt, (3R-cis)-; UNII-74573Q728X component FZCWCSNK. Grade: 98%. CAS No. 158102-98-8. Molecular formula: C28H23ClF3N2NaO6S. Mole weight: 630.99. | |
| CP2 | CP2 is a cyclic peptide and it is an inhibitor of the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively. Grade: ≥97%. Molecular formula: C92H120N24O26S. Mole weight: 2010.15. | |
| CP21R7 | CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grade: >98%. CAS No. 125314-13-8. Molecular formula: C19H15N3O2. Mole weight: 317.34. | |
| CP-220629 | CP-220629, a Pyrazolopyridin derivative, has been found to be a Type 4 cyclic nucleotide phosphodiesterase inhibitor that was once studied as an anti-inflammatory as well as antiasthmatic agent. Synonyms: UNII-BAV9N49AFE; CP-220629; CP 220629; CP220629; BAV9N49AFE; SCHEMBL84865; CHEMBL75819; 1-cyclopentyl-3-ethyl-6-(2-methylphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one. Grade: 98%. CAS No. 162141-96-0. Molecular formula: C20H25N3O. Mole weight: 323.44. | |
| CP22185 | CP22185 is a catecholamine-uptake inhibitor. Synonyms: CP-22185; CP 22185; Sertraline hydrochloride specified impurity B; (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine; N-Methyl-4alpha-phenyltetralin-1alpha-amine. Grade: 98%. CAS No. 52758-03-9. Molecular formula: C17H19N. Mole weight: 237.34. | |
| CP 226269 | CP 226269 is a selective dopamine D4 agonist. Synonyms: CP-226269; CP 226269; CP226269; 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole. Grade: 99%. CAS No. 220941-93-5. Molecular formula: C18H19FN4. Mole weight: 310.37. | |
| CP 24,879 hydrochloride | CP 24,879 is an inhibitor of arachidonic acid biosynthesis by inhibition of Δ5/Δ6 desaturase. Synonyms: p-(Isopentyloxy)-aniline; 4-(3-methylbutoxy)-benzenamine monohydrochloride. Grade: ≥98%. CAS No. 10141-51-2. Molecular formula: C11H17NO·HCl. Mole weight: 215.8. | |
| CP-283097 | CP-283097 is NR2B N-Methyl-D-Aspartate receptor antagonist originated by Pfizer. Preclinical trials for the treatment of Migraine and Neurodegenerative disorders were discontinued. Uses: Migraine; neurodegenerative disorders. Synonyms: CP-283097; CP283097; CP 283097; UNII-WHL1Z3GN15; ; (3R,4S)-Rel-3,4-dihydro-3-(4-hydroxy-4-(phenylmethyl)-1-piperidinyl)-2H-1-benzopyran-4,7-diol. Grade: 98%. CAS No. 138047-56-0. Molecular formula: C21H25NO4. Mole weight: 355.43. | |
| CP-28888 | CP-28888, an interferon inducer, is more effective in mice, but less active in humans and lacks anti-rhinovirus effects. Synonyms: CP 28888-27; N,N-Dihexadecyl-1,3-benzenedi(methanamine); 1,3-Benzenedimethanamine, N1,N3-dihexadecyl-; N,N'-[1,3-Phenylenebis(methylene)]di(hexadecan-1-amine); N,N'-[1,3-Phenylenebis(methylene)]di(1-hexadecanamine). Grade: ≥95%. CAS No. 69938-75-6. Molecular formula: C40H76N2. Mole weight: 585.04. | |
| CP-289 | CP-289 is an effective C5a receptor antagonist with an IC50 of 1 μM. Grade: >98.0%. CAS No. 1349637-14-4. Molecular formula: C30H35ClN2O2. Mole weight: 491.07. | |
| Cp2C / CppC | Cp2C is an omnipresent chemical compound extensively employed in the realm of biomedical industry, recognized for its profound efficacy in restraining the proliferation of cancerous cells, primarily manifested in breast and lung malignancies. Synonyms: P1, P2- Di- (cytidine- 5')- diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 29789-88-6. Molecular formula: C18H26N6O15P2 (free acid). Mole weight: 628.4 (free acid). | |
| CP2 (Nic) | CP2 (Nic) is an efficacious and discriminating allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR), and exhibits potential utility as a treatment for cognitive deficits linked with Alzheimer's disease. Synonyms: Nicotinamide cytosine dinucleotide, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H27N5O15P2 (free acid). Mole weight: 639.40 (free acid). | |
| Cp2-SO4 | Cp2-SO4, a phenylalanine derivative, reverses interleukin 4 induced 1 (IL4I1)-dependent inhibition of T-cell proliferation with Ki of 21.2 μM. Molecular formula: C14H23NO6S. Mole weight: 333.40. | |
| CP 31398 | CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-; 1,3-Propanediamine, N'-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-; N3-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine; CP31398; CP-31398. Grade: ≥95%. CAS No. 259199-65-0. Molecular formula: C22H26N4O. Mole weight: 362.47. | |
| CP 31398 dihydrochloride | CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: CP31398 dihydrochloride; CP-31398 dihydrochloride; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride; 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride (1:2); PZ 0115; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1217195-61-3. Molecular formula: C22H26N4O.2HCl. Mole weight: 435.39. | |
| CP 31398 dihydrochloride hydrate | CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride, hydrate (1:2:1); CP31398 dihydrochloride hydrate; CP-31398 dihydrochloride hydrate; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride hydrate. Grade: ≥95%. CAS No. 1853109-76-8. Molecular formula: C22H26N4O.2HCl.H2O. Mole weight: 453.41. | |
| CP-316311 | CP-316311, a pyridine derivative, has been found to be a CRF 1 receptor antagonist and was once studied as an antidepressant agent by Pfizer. IC50: 6.8 nM. Synonyms: CP-316311; CP 316311; CP316311; CP-316,311; CP 316,311; CP316,311; Pyridine, 4-(1-ethylpropoxy)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-. Grade: 98%. CAS No. 175139-41-0. Molecular formula: C21H29NO2. Mole weight: 327.47. | |
| CP 316819 | CP 316819 has been found to be a glycogen phosphorylase inhibitor and could probably be used in the treatment for glycemic control in type 2 diabetes. Synonyms: CP 316819; CP316819; CP-316819; 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide. Grade: ≥98% by HPLC. CAS No. 186392-43-8. Molecular formula: C21H22ClN3O4. Mole weight: 415.87. | |
| CP-320626 | CP-320626, a carboxamide derivative, is a potent glycogen phosphorylase inhibitor and a possible target for type 2 diabetes therapy. CP-320626 is also a potent inhibitor of human muscle GPa. Synonyms: 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide; CP-320626; CP320626; CP 320626. Grade: >98%. CAS No. 186430-23-9. Molecular formula: C23H23ClFN3O3. Mole weight: 443.90. | |
| CP-331684 | CP-331684 is a β3-adrenergic receptor agonist used as antidiabetic drug. Synonyms: CP-331684; CP331684; CP 331684; UNII-9EY0MGZ7F8. 2-[4-[2-[[(2R)-2-(6-aminopyridin-3-yl)-2-hydroxyethyl]amino]ethoxy]phenyl]acetic acid. Grade: >98%. CAS No. 207922-70-1. Molecular formula: C17H21N3O4. Mole weight: 331.37. | |
| CP 339818 | CP 339818 is a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine; 1-Benzyl-N-pentylquinolin-4(1H)-imine; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine. Grade: ≥95%. CAS No. 185855-91-8. Molecular formula: C21H24N2. Mole weight: 304.43. | |
| CP 339818 hydrochloride | CP 339818 hydrochloride is the hydrochloride salt form of CP 339818, a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, hydrochloride (1:1); 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, monohydrochloride; Cp 339818 monohydrochloride; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine hydrochloride; 1-Benzyl-N-pentylquinolin-4(1H)-imine hydrochloride; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 478341-55-8. Molecular formula: C21H24N2.HCl. Mole weight: 340.89. | |
| CP 346086 | CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48. | |
| CP 376395 | CP 376395 is a potent and selective CRF1 receptor antagonist. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP-376395; CP376395. Grade: >99 %. CAS No. 175140-00-8. Molecular formula: C21H30N2O. Mole weight: 326.5. | |
| CP-376395 HCl | CP-376395 HCl is a potent and selective CRF1 receptor antagonist with Ki values of 12 and >10000 nM for CRF1 and CRF2 receptors respectively. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP376395 HCl; CP 376395 HCl; 2-(Mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine hydrochloride; 3,6-Dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine hydrochloride. Grade: >98 %. CAS No. 1013933-37-3. Molecular formula: C21H31ClN2O. Mole weight: 362.94. | |
| CP-394531 | CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-394531; CP 394531; CP394531; UNII-227D9ED2SI. (2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol. Grade: ≥95%. CAS No. 305822-63-3. Molecular formula: C23H23ClO2. Mole weight: 366.14. | |
| CP-409092 | CP-409092 is a GABA(A) partial agonist developed for the treatment of General Anxiety Disorder (GAD) and presents an interesting phenomenon of human pharmacokinetic predictions. In vitro, CP-409092 was abroadly metabolized in rat and human systems predominantly to acid metabolite formed by oxidative deamination of the N-methyl group of CP-409092 mediated by MAO-A (as deduced from inhibition experiments). Synonyms: N-[4-(methylaminomethyl)phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide; 4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (4-methylaminomethylphenyl)amide; CP 409,092; CP 409092; CP-409,092; CP-409092; CP409,092; CP409092. Grade: >98%. CAS No. 194098-25-4. Molecular formula: C17H19N3O2. Mole weight: 297.35. | |
| CP-409092 hydrochloride | CP-409092 hydrochloride is a GABAA receptor partial agonist for the treatment of general anxiety disorder (GAD). Synonyms: N-(4-((Methylamino)methyl)phenyl)-4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxamide hydrochloride; 1H-Indole-3-carboxamide, 4,5,6,7-tetrahydro-N-[4-[(methylamino)methyl]phenyl]-4-oxo-, hydrochloride (1:1). Grade: ≥95%. CAS No. 225240-86-8. Molecular formula: C17H20ClN3O2. Mole weight: 333.81. | |
| CP 424174 | CP 424174 has been found to be an inhibitor of stimulus-coupled IL-1β post-translational processing. Synonyms: CP-424174; CP 424174; CP424174; CP-424,174; CP 424,174; CP424,174; N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide. Grade: ≥98% by HPLC. CAS No. 210825-31-3. Molecular formula: C22H29ClN2O4S. Mole weight: 452.99. | |
| CP-432 | CP-432 is an EP4 prostaglandin agonist , potential useful for the treatment of glaucoma and ocular hypertension. Uses: An ep4 prostaglandin agonist. Synonyms: CP-432; CP 432; CP432; CP-734432; CP 734432; CP734432. 5-(3-((2S)-2-((3R)-3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxo-1-pyrrolidinyl)propyl)-2-Thiophenecarboxylic acid. Grade: ≥95%. CAS No. 431990-08-8. Molecular formula: C23H26F3NO4S. Mole weight: 469.52. | |
| CP-456773 sodium | CP-456773, also known as MCC950 and CRID3, is a potent, orally bioavailable NLRP3 inflammasome inhibitor and inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production for the treatment of inflammatory diseases. Synonyms: sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide; MCC950; MCC 950; MCC-950; CP-45677; CP45677; CP 45677; CRID-3; CRID3; CRID 3; CP-456773 sodium salt; CP 456773 sodium salt; CP456773 sodium salt; Cytokine release inhibitory drug 3. CAS No. 256373-96-3. Molecular formula: C20H24N2NaO5S. Mole weight: 427.46. | |
| CP-457677 | CP-457677, also called as TX006169, is a JNK inhibitor. Synonyms: 2-(4-fluorophenoxy)-N-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]pyridine-3-carboxamide; CP-457677; CP457677; CP 457677; UNII-5A83419M4U. Grade: >98%. CAS No. 214535-77-0. Molecular formula: C22H21FN2O3. Mole weight: 380.41. | |
| CP-457920 | CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the treatment of Vascular dementia but discontinued. Synonyms: N-benzyl-6-ethoxy-4-oxo-1H-1,5-naphthyridine-3-carboxamide; CP-457920; CP457920; CP 457920; UNII-13BME2F602; CP-457,920. Grade: >98%. CAS No. 220860-50-4. Molecular formula: C18H17N3O3. Mole weight: 323.35. | |
| CP 461 | CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; hydrochloride; CAS: 227619-92-3 (CP-461 free base). Grade: >98%. CAS No. 227619-96-7. Molecular formula: C25H22ClFN2O. Mole weight: 420.91. | |
| CP-461 free base | CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP-461 free base; CP 461 free base; CP461 free base; N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; UNII-824ZMS3BGL; OSI-461 free base. Grade: >98%. CAS No. 227619-92-3. Molecular formula: C25H21FN2O. Mole weight: 384.45. | |
| CP 465022 | CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons). CP 465022 provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models. Synonyms: 3-(2-chlorophenyl)-2-[2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-465022; CP 465022; CP465022; UNII-4582JTR93Y. Grade: >99 %. CAS No. 199655-36-2. Molecular formula: C26H24ClFN4O. Mole weight: 499.41. | |
| CP-465022 hydrochloride | CP-465022 hydrochloride, a potent, selective and non-competitive AMPA receptor antagonist with anticonvulsant activity, is against Kainate-induced response with an IC50 of 25 nM in rat cortical neurons. Synonyms: 3-(2-Chlorophenyl)-2-[(E)-2-{6-[(diethylamino)methyl]pyridin-2-yl}vinyl]-6-fluoroquinazolin-4(3H)-one hydrochloride (1:1); 4(3H)-Quinazolinone, 3-(2-chlorophenyl)-2-[(E)-2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-, hydrochloride (1:1); (E)-3-(2-chlorophenyl)-2-(2-(6-((diethylamino)methyl)pyridin-2-yl)vinyl)-6-fluoroquinazolin-4(3H)-one hydrochloride. CAS No. 1785666-59-2. Molecular formula: C26H25Cl2FN4O. Mole weight: 499.41. | |
| CP-465022 maleate | CP-465022 is a selective, non-competitive AMPA antagonist that displays potent anticonvulsant activity. Synonyms: CP-465022 (maleate); 199656-46-7; cp-465022 maleate; (Z)-but-2-enedioic acid; 3-(2-chlorophenyl)-2-[(E)-2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-392,110 (maleate); 3-(2-chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone-(2Z)-2-butenedioate; SCHEMBL8301393; CP465022(2Z)-2-butenedioate; ZHA65646; HY-18663A; AKOS037643494; CP 465022 (2Z)-2-butenedioate; AS-16611; CS-0013530. CAS No. 199656-46-7. Molecular formula: C26H24ClFN4O·C4H4O4. Mole weight: 579. | |
| CP 46665 | CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice. Uses: Anti-tumor. Synonyms: CP 46665; CP46665; CP-46665; CP-46,665. 4-Aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine. Grade: 98%. CAS No. 72618-10-1. Molecular formula: C35H66Cl2N2O2. Mole weight: 617.82. | |
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